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Journal of Pharmaceutical Policy and Practice

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https://www.readbyqxmd.com/read/29034096/evaluating-the-impact-of-brexit-on-the-pharmaceutical-industry
#1
REVIEW
Fawz Kazzazi, Cleo Pollard, Paul Tern, Alejandro Ayuso-Garcia, Jack Gillespie, Inesa Thomsen
INTRODUCTION: The UK Pharmaceutical Industry is arguably one of the most important industries to consider in the negotiations following the Brexit vote. Providing tens of thousands of jobs and billions in tax revenue and research investment, the importance of this industry cannot be understated. At stake is the global leadership in the sector, which produces some of the field's most influential basic science and translation work. However, interruptions and losses may occur at multiple levels, affecting patients, researchers, universities, companies and government...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/29026611/branded-prescription-drug-spending-a-framework-to-evaluate-policy-options
#2
Jeromie Ballreich, G Caleb Alexander, Mariana Socal, Taruja Karmarkar, Gerard Anderson
BACKGROUND: High drug spending is a concern for policy makers due to limits on access for patients. Numerous policies have been proposed to address high drug spending. The existence of multifarious proposals makes it difficult for policy makers to consider all the alternatives. We developed an approach to select the most viable options to present to policy makers. METHODS: We identified 41 different proposals in the peer-reviewed literature to reduce the level of spending or change the incentives for branded prescription drugs; ten of which we identified as promising proposals...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28948025/does-access-to-credit-services-influence-availability-of-essential-child-medicines-and-licensing-status-among-private-medicine-retail-outlets-in-uganda
#3
Lorraine Nabbanja Kabunga, Paschal Mujasi
BACKGROUND: Despite making great progress in reducing under five mortality in the last three decades. Uganda still ranks high among countries with the highest under five mortality rates. More than a third (36%) of these deaths are caused by pneumonia (15%), malaria (12%), or diarrhea (9%). For many mothers and caregivers, private drug shops are a point of care seeking for these illnesses. However, many drug-shops, are unlicensed and do not stock essential commodities due to insufficient capital and operational funds...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28919978/controlled-substance-agreements-for-opioids-in-a-primary-care-practice
#4
Lindsey M Philpot, Priya Ramar, Muhamad Y Elrashidi, Raphael Mwangi, Frederick North, Jon O Ebbert
BACKGROUND: Opioids are widely prescribed for chronic non cancer pain (CNCP). Controlled substance agreements (CSAs) are intended to increase adherence and mitigate risk with opioid prescribing. We evaluated the demographic characteristics of and opioid dosing for patients with CNCP enrolled in CSAs in a primary care practice. METHODS: We conducted a retrospective cohort study of 1066 patients enrolled in CSAs between May 9, 2013 and August 15, 2016 for CNCP in a Midwest primary care practice...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28904801/hypnotics-use-in-children-0-18%C3%A2-months-moderate-agreement-between-mother-reported-survey-data-and-prescription-registry-data
#5
Ingvild Holdø, Jørgen G Bramness, Marte Handal, Leila Torgersen, Ted Reichborn-Kjennerud, Eivind Ystrøm, Hedvig Nordeng, Svetlana Skurtveit
BACKGROUND: Different methods in pharmacoepidemiology can be used to study hypnotic use in children. But neither questionnaire-based data nor prescription records can be considered a "gold standard". This study aimed to investigate the agreement between mother-reported questionnaire-based data and prescription record data for hypnotic drugs in children aged 0-18 months. The agreement was compared to the agreement for a group of antiepileptic drugs. METHODS: Prescription record data were collected from the Norwegian prescription database for 47,413 children also surveyed in the Norwegian mother and child cohort between 2005 and 2009...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28878929/antimicrobial-resistance-in-india
#6
Isha Patel, Rabia Hussain, Anam Khan, Akram Ahmad, Muhammad Umair Khan, Mohamed Azmi Ahmed Hassalai
No abstract text is available yet for this article.
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28878928/evaluation-of-a-guided-continuous-quality-improvement-program-in-community-pharmacies
#7
Chanadda Chinthammit, Michael T Rupp, Edward P Armstrong, Tara Modisett, Rebecca P Snead, Terri L Warholak
BACKGROUND: The importance of creating and sustaining a strong culture of patient safety has been recognized as a critical component of safe medication use. This study aims to assess changes in attitudes toward patient safety culture and frequency of quality-related event (QRE) reporting after guided implementation of a continuous quality improvement (CQI) program in a panel of community pharmacies in the United States (U.S.). METHODS: Twenty-one community pharmacies volunteered to participate in the project and were randomly assigned to intervention or control groups...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28852529/evaluating-insulin-information-provided-on-discharge-summaries-in-a-secondary-care-hospital-in-the-united-kingdom
#8
Amie Bain, Lois Nettleship, Sallianne Kavanagh, Zaheer-Ud-Din Babar
BACKGROUND: Prescribing errors at the time of hospital discharge are common and could potentially lead to avoidable patient harm, especially when they involve insulin, a high-risk medicine widely used for the treatment of diabetes mellitus. When information regarding insulin therapy is not sufficiently communicated to a patient's primary care provider, continuity of care for patients with diabetes may be compromised. The objectives of this study were to investigate the nature and prevalence of insulin-related medication discrepancies contained in hospital discharge summaries for patients with diabetes...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28808578/antibiotic-use-during-pregnancy-a-retrospective-study-of-prescription-patterns-and-birth-outcomes-at-an-antenatal-clinic-in-rural-ghana
#9
Kwesi Boadu Mensah, Kwame Opoku-Agyeman, Charles Ansah
BACKGROUND: Babies are increasingly being exposed to antibiotics intrapartum in the bid to reduce neonatal and maternal deaths. Intrapartum antibiotic exposure, including even those considered safe in pregnancy, have been associated with childhood obesity and compromised immunity. Data on the extent of antibiotic use, safety and its impact on birth outcomes and neonatal health in Sub-Saharan Africa is very limited. This study sought to ascertain the extent of antibiotic use in pregnancy and its effects on birth outcomes in a rural hospital in Ghana...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28785413/drug-utilization-patterns-among-elderly-hospitalized-patients-on-poly-pharmacy-in-punjab-pakistan
#10
Muhammad Rehan Sarwar, Muhammad Atif, Shane Scahill, Anum Saqib, Muhammad Qamar-Uz-Zaman, Zaheer Babar
BACKGROUND: Reports from drug utilization reviews are important tools employed in the assessment of healthcare practices. The objective of this study was to evaluate drug utilization patterns among elderly hospitalized patients on poly-pharmacy regimens in Pakistan. METHODS: A descriptive, non-experimental, cross-sectional study was carried out from December 2015 to March 2016 in six tertiary-care hospitals in the Punjab province of Pakistan. The population under study were patients aged ≥60 years, taking ≥5 medicines per day (i...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28725441/taking-the-lead-from-our-colleagues-in-medical-education-the-use-of-images-of-the-in-vivo-setting-in-teaching-concepts-of-pharmaceutical-science
#11
Louise E Curley, Julia Kennedy, Jordan Hinton, Ali Mirjalili, Darren Svirskis
Despite pharmaceutical sciences being a core component of pharmacy curricula, few published studies have focussed on innovative methodologies to teach the content. This commentary identifies imaging techniques which can visualise oral dosage forms in-vivo and observe formulation disintegration in order to achieve a better understanding of in-vivo performance. Images formed through these techniques can provide students with a deeper appreciation of the fate of oral formulations in the body compared to standard disintegration and dissolution testing, which is conducted in-vitro...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28702204/exploring-the-status-of-retail-private-drug-shops-in-bangladesh-and-action-points-for-developing-an-accredited-drug-shop-model-a-facility-based-cross-sectional-study
#12
Syed Masud Ahmed, Nahitun Naher, Tarek Hossain, Lal Bahadur Rawal
BACKGROUND: The private retail drug shops market in Bangladesh is largely unregulated and unaccountable, giving rise to irrational use of drugs and high Out-of-pocket expenditure on health. These shops are served by salespersons with meagre or no formal training in dispensing. METHOD: This facility-based cross-sectional study was undertaken to investigate how the drug shops currently operate vis-a-vis the regulatory regime including dispensing practices of the salespersons, for identifying key action points to develop an accredited model for Bangladesh...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28702203/the-effectiveness-of-naltrexone-combined-with-current-smoking-cessation-medication-to-attenuate-post-smoking-cessation-weight-gain-a-literature-review
#13
REVIEW
Raewyn Rees, Ali Seyfoddin
BACKGROUND: Smoking is the number one cause of preventable morbidity and mortality globally and although many countries have invested heavily in smoking cessation programs, 21% of the global population still smoke. Post cessation weight gain has been identified as a barrier to attempting cessation and is implicated in the high rates of relapse. Naltrexone has been touted as a possible solution to address post smoking cessation weight gain. RESULTS: The results from seven original studies assessing the effectiveness of naltrexone in combination with existing smoking cessation medications to attenuate post smoking cessation weight gain were obtained and critically reviewed...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28670455/data-exclusivity-exceptions-and-compulsory-licensing-to-promote-generic-medicines-in-the-european-union-a-proposal-for-greater-coherence-in-european-pharmaceutical-legislation
#14
REVIEW
Ellen F M 't Hoen, Pascale Boulet, Brook K Baker
The challenge of providing access to high-priced patented medicines is a global problem affecting all countries. A decade and a half ago the use of flexibilities contained in the World Trade Organization Agreement on Trade Related Aspects of Intellectual Property Rights, in particular compulsory licensing, was seen as a mechanism to respond to high-price medicines for the treatment of HIV/AIDS in low- and middle-income countries. Today a number of upper-income European Union (EU) Member States are contemplating the use of compulsory licensing in their efforts to reduce expenditure on pharmaceutical products...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28588896/promoting-transparency-accountability-and-access-through-a-multi-stakeholder-initiative-lessons-from-the-medicines-transparency-alliance
#15
Taryn Vian, Jillian C Kohler, Gilles Forte, Deirdre Dimancesco
BACKGROUND: Barriers to expanding access to medicines include weak pharmaceutical sector governance, lack of transparency and accountability, inadequate attention to social services on the political agenda, and financing challenges. Multi-stakeholder initiatives such as the Medicines Transparency Alliance (MeTA) may help overcome these barriers. Between 2008 and 2015, MeTA engaged stakeholders in the pharmaceutical sectors of seven countries (Ghana, Jordan, Kyrgyzstan, Peru, Philippines, Uganda, and Zambia) to promote access goals through greater transparency...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28523128/comparison-of-medicines-management-strategies-in-insurance-schemes-in-middle-income-countries-four-case-studies
#16
Warren A Kaplan, Paul G Ashigbie, Mohamad I Brooks, Veronika J Wirtz
BACKGROUND: Many middle-income countries are scaling up health insurance schemes to provide financial protection and access to affordable medicines to poor and uninsured populations. Although there is a wealth of evidence on how high income countries with mature insurance schemes manage cost-effective use of medicines, there is limited evidence on the strategies used in middle-income countries. This paper compares the medicines management strategies that four insurance schemes in middle-income countries use to improve access and cost-effective use of medicines among beneficiaries...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28503310/individual-capacity-building-approaches-in-a-global-pharmaceutical-systems-strengthening-program-a-selected-review
#17
Niranjan Konduri, Megan Rauscher, Shiou-Chu Judy Wang, Tanya Malpica-Llanos
BACKGROUND: Medicines use related challenges such as inadequate adherence, high levels of antimicrobial resistance and preventable adverse drug reactions have underscored the need to incorporate pharmaceutical services to help achieve desired treatment outcomes, and protect patients from inappropriate use of medicines. This situation is further constrained by insufficient numbers of pharmaceutical personnel and inappropriate skill mix. Studies have addressed individual capacity building approaches of logistics, supply chain or disease specific interventions but few have documented those involving such pharmacy assistants/professionals, or health workers/professionals charged with improving access and provision of pharmaceutical services...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28465829/two-years-post-affordable-medicines-facility-for-malaria-program-availability-and-prices-of-anti-malarial-drugs-in-central-ghana
#18
Alexander Freeman, Anthony Kwarteng, Lawrence Gyabaa Febir, Seeba Amenga-Etego, Seth Owusu-Agyei, Kwaku Poku Asante
BACKGROUND: The Affordable Medicines Facility for malaria (AMFm) Program was a subsidy aimed at artemisinin-based combination therapies (ACTs) in order to increase availability, affordability, and market share of ACTs in 8 malaria endemic countries in Africa. The WHO supervised the manufacture of the subsidized products, named them Quality Assured ACTs (QAACT) and printed a Green Leaf Logo on all QAACT packages. Ghana began to receive the subsidized QAACTs in 2010. METHODS: A cross-sectional stock survey was conducted at 63 licensed chemical shops (LCS) and private pharmacies in two districts of the Brong-Ahafo region of Ghana to determine the availability and price of all anti-malarial treatments...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28405339/ethiopian-patients-perceptions-of-anti-diabetic-medications-implications-for-diabetes-education
#19
Bruck Messele Habte, Tedla Kebede, Teferi Gedif Fenta, Heather Boon
BACKGROUND: The purpose of this study is to explore medication-related perceptions of adult patients with type 2 diabetes attending treatment in public hospitals of urban centers in central Ethiopia. METHODS: Qualitative in-depth interviews were held with 39 participants selected to represent a range of treatment experiences and socio-demographic characteristics who were attending their treatment in 3 public hospitals. Interviews continued until key themes were saturated...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28392925/antibiotic-knowledge-attitudes-and-behaviours-of-albanian-health-care-professionals-and-patients-a-qualitative-interview-study
#20
Susanne Kaae, Admir Malaj, Iris Hoxha
BACKGROUND: The inappropriate use of antimicrobials is a problem worldwide. To target future interventions, a thorough understanding of the reasons behind this current behaviour is needed. Within the EU, the culture of antimicrobial use has been intensely studied, but this is not the case in non-EU southeastern European countries, despite the frequent use of (broad-spectrum) antibiotics (ABs) in this region. The aim of this study was to explore AB knowledge, attitudes and behaviours of health care professionals (HCPs) and patients in one southeastern European country, Albania...
2017: Journal of Pharmaceutical Policy and Practice
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