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https://www.readbyqxmd.com/read/29201660/operational-aspects-of-bedaquiline-implementation-in-swaziland-report-from-the-field
#1
D Vambe, T Dlamini, J Furin, C Gracia-Edwards, K Keus, K Kunene, A Shabangu, S N Dlamini, W Sikhondze
Bedaquiline (BDQ) has been recommended by the World Health Organization for the treatment of multi-drug-resistant tuberculosis (MDR-TB) since 2013, but experience using the drug in high-burden, lower-income countries is limited and case studies are needed. Swaziland started using BDQ under national TB programme conditions in 2015 in four pilot sites. As of 1 December 2016, 93 patients had been initiated on BDQ, i.e., 19% of MDR-TB patients treated in the country. Swaziland has developed a systematic and efficient model for BDQ introduction in collaboration with several partners...
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29201659/mental-disorders-and-drug-alcohol-use-in-patients-commencing-extensively-drug-resistant-tuberculosis-treatment
#2
J Scuffell, D Boccia, F Garcia Velarde, S R Leon, G Raviola, L Lecca, J T Galea
Mental disorders and alcohol/drug use worsen treatment outcomes for multidrug-resistant tuberculosis (TB), but data are lacking for extensively drug-resistant (XDR) TB. We investigated the association of baseline mental disorders and alcohol/drug use on XDR-TB treatment outcomes in a retrospective study of 53 XDR-TB Peruvian patients during 2010-2012. Logistic regression estimated the odds ratios for unfavourable XDR-TB treatment outcomes. Overall treatment success was 25%. Mental disorders and drug/alcohol use were found in respectively 22...
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29201658/closing-the-gap-decentralising-mental-health-care-to-primary-care-centres-in-one-rural-district-of-rwanda
#3
B Nyirandagijimana, J K Edwards, E Venables, E Ali, C Rusangwa, H Mukasakindi, R Borg, M Fabien, M Tharcisse, A Nshimyiryo, P H Park, G J Raviola, S L Smith
Setting: Programmes that integrate mental health care into primary care settings could reduce the global burden of mental disorders by increasing treatment availability in resource-limited settings, including Rwanda. Objective: We describe patient demographics, service use and retention of patients in care at health centres (HC) participating in an innovative primary care integration programme, compared to patients using existing district hospital-based specialised out-patient care. Design: This was a retrospective cohort study using routinely collected data from six health centres and one district hospital from October 2014 to March 2015...
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29201657/tuberculosis-among-migrants-in-bishkek-the-capital-of-the-kyrgyz-republic
#4
O Goncharova, O Denisiuk, R Zachariah, K Davtyan, D Nabirova, C Acosta, A Kadyrov
Setting: Twenty-two first-line, two second-line and one tertiary health facility in Bishkek, the capital of Kyrgyzstan. Objectives: Among migrants, a marginalised population at risk for acquiring and transmitting tuberculosis (TB), we determined the proportion with TB among all registered TB cases. For those registered at primary-level facilities, we then reported on their demographic and clinical profiles and TB treatment outcomes. Design: This was a retrospective cohort analysis of 2012-2013 programme data...
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29201656/age-stratified-tuberculosis-treatment-outcomes-in-zimbabwe-are-we-paying-attention-to-the-most-vulnerable
#5
R T Ncube, K C Takarinda, C Zishiri, W van den Boogaard, N Mlilo, C Chiteve, N Siziba, F Trinchán, C Sandy
Setting: A high tuberculosis (TB) incidence, resource-limited urban setting in Zimbabwe. Objectives: To compare treatment outcomes among people initiated on first-line anti-tuberculosis treatment in relation to age and other explanatory factors. Design: This was a retrospective record review of routine programme data. Results: Of 2209 patients included in the study, 133 (6%) were children (aged <10 years), 132 (6%) adolescents (10-19 years), 1782 (81%) adults (20-59 years) and 162 (7%) were aged ⩾60 years, defined as elderly...
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29201655/childhood-tuberculosis-in-mauritania-2010-2015-diagnosis-and-outcomes-in-nouakchott-and-the-rest-of-the-country
#6
B Aw, S Ade, S G Hinderaker, N Dlamini, K C Takarinda, K Chiaa, A Feil, A Traoré, T Reid
Setting: The National Tuberculosis Programme, Mauritania. Objective: To compare the diagnosis and treatment outcomes of childhood tuberculosis (TB) cases (aged <15 years) registered between 2010 and 2015 inside and outside Nouakchott, the capital city. Design: This was a retrospective comparative cohort study. Results: A total of 948 children with TB were registered. The registration rate was 10 times higher in Nouakchott. The proportion of children among all TB cases was higher inside than outside Nouakchott (7...
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29201654/increasing-isoniazid-preventive-therapy-uptake-in-an-hiv-program-in-rural-papua-new-guinea
#7
A Carmone, C A Rodriguez, T D Frank, M Kiromat, P W Bongi, R G Kuno, T Palou, M F Franke
Setting: Tuberculosis (TB) is the leading cause of death among people living with the human immunodeficiency virus (PLHIV) in Papua New Guinea. Despite a policy for isoniazid preventive therapy (IPT) among PLHIV, implementation has been slow. Objective: We prospectively evaluated a standardized guided screening process, including TB diagnostic support, to increase IPT initiation in adult PLHIV on antiretro-viral treatment. Design: The guided process included a paper-based IPT screening tool that prompted review of patient history and TB symptoms and sputum analysis by smear microscopy and Xpert® MTB/RIF...
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29201653/why-are-hiv-infected-people-not-started-on-antiretroviral-therapy-a-mixed-methods-study-from-gujarat-india
#8
S Chawla, K Shringarpure, B Modi, R Sharma, B B Rewari, A N Shah, P B Verma, A R Dongre, A M V Kumar
Setting: Five purposively selected antiretroviral therapy (ART) centres in Gujarat, India. Objectives: To assess the proportion of ART-eligible people living with the human immunodeficiency virus (PLHIV) who were not initiated on ART within 2 months of being recorded as eligible, to identify factors associated with non-initiation and to explore reasons from the provider's perspective. Design: We used a mixed-methods design (triangulation) of 1) a quantitative phase involving record reviews and cohort analysis (Poisson regression) of PLHIV registered during April 2014-March 2015, and 2) a qualitative phase involving one-to-one interviews with 25 providers...
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29201652/tackling-latent-tuberculous-infection-as-part-of-a-strategy-for-achieving-tuberculosis-elimination-targets-in-china
#9
EDITORIAL
Lixia Wang, Lin Zhou, Jun Cheng, Yan Lin
No abstract text is available yet for this article.
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29201651/mental-disease-alcoholism-and-xdr-tb-loss-to-follow-up-and-resistance-the-cost-of-an-inadequate-approach
#10
EDITORIAL
Ignacio Monedero
No abstract text is available yet for this article.
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/29018769/homeless-shelter-context-and-tuberculosis-illness-experiences-during-a-large-outbreak-in-atlanta-georgia
#11
W J Connors, S A Hussen, D P Holland, O Mohamed, K L Andes, N D Goswami
Setting: Persons experiencing homelessness (PEH) represent a population at high risk for tuberculosis (TB). While quantitative studies have characterized some important features of this key group, less has been captured directly from PEH about how they experience TB illness itself and the prevention and control measures implemented in response to an outbreak. This qualitative study aimed to explore PEH's TB disease experiences in the context of a large TB outbreak involving homeless shelters in Atlanta, Georgia, USA...
September 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/28913174/research-ethics-committees-in-the-pacific-islands-gaps-and-opportunities-for-health-sector-strengthening
#12
J T Denholm, K Bissell, K Viney, A M Durand, H L Cash, C Roseveare, O E Merilles, A D Harries, S Biribo
There has been a range of developments in recent years to stimulate increasing public health research activity throughout the Pacific. Development of local capacity for ethics committee review and oversight is, however, frequently underdeveloped. This is reflected in the number of Pacific Island nations where ethics committees have not been established or where only informal processes exist for ethics review and oversight. This is problematic for the optimal development of relevant and culturally appropriate research, and building up local ethics committees should be part of continued research development in the Pacific...
March 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/28913173/-leaving-no-one-behind-how-community-health-workers-can-contribute-to-achieving-the-sustainable-development-goals
#13
EDITORIAL
Dermot Maher
No abstract text is available yet for this article.
March 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/28913172/finding-tuberculosis-in-prisons-in-india-who-benefits
#14
EDITORIAL
Nevin Wilson
No abstract text is available yet for this article.
March 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/28913171/development-of-capacity-for-research-ethics-review-in-low-and-middle-income-countries-need-for-a-systems-approach
#15
EDITORIAL
Vijayaprasad Gopichandran
No abstract text is available yet for this article.
March 21, 2017: Public Health Action
https://www.readbyqxmd.com/read/28123967/the-effects-of-placing-an-operational-research-fellow-within-the-viet-nam-national-tuberculosis-programme
#16
N B Hoa, N V Nhung, A M V Kumar, A D Harries
In April 2009, an operational research fellow was placed within the Viet Nam National Tuberculosis Control Programme (NTP). Over the 6 years from 2010 to 2015, the OR fellow co-authored 21 tuberculosis research papers (as principal author in 15 [71%]). This constituted 23% of the 91 tuberculosis papers published in Viet Nam during this period. Of the 21 published papers, 16 (76%) contributed to changes in policy (n = 8) and practice (n = 8), and these in turn improved programme performance. Many papers also contributed important evidence for better programme planning...
December 21, 2016: Public Health Action
https://www.readbyqxmd.com/read/28123966/universal-institutional-delivery-among-mothers-in-a-remote-mountain-district-of-nepal-what-are-the-challenges
#17
D Joshi, S C Baral, S Giri, A M V Kumar
Setting: Eight village development committees of Mugu District, a remote mountainous district of Nepal that has poor maternal health indicators. Objectives: 1) To assess the proportion of mothers who delivered in health facilities (institutional delivery); 2) among mothers who delivered at home, to understand their reasons for doing so; and 3) among mothers who delivered in health facilities, to understand their challenges. Design: Cross-sectional study involving semi-structured interviews with mothers conducted in 2015...
December 21, 2016: Public Health Action
https://www.readbyqxmd.com/read/28123965/should-kiribati-continue-to-aim-for-100-voluntary-non-remunerated-blood-donation-as-recommended-by-the-who
#18
G Tauma, A D Harries, O E A Merilles, R Tekoaua, B Teriboriki
Setting: Tungaru Central Hospital Blood Bank Laboratory, Nawerewere, Tarawa, Kiribati. Objective: To determine characteristics, deferrals and reasons for deferral amongst blood donors from 2011 to 2016. Design: A cross-sectional study using routinely collected data. Results: From January 2011 to March 2016, 8531 potential blood donors were registered. For each full year, the proportion of voluntary non-remunerated blood donors (VNRBD) was below 10%, although it increased to 13% in 2015. The overall proportion of blood donors deferred increased each year over the 5-year period, from 44% to 57%, with similar increases in deferrals in VNRBD and family replacement donors (FRD)...
December 21, 2016: Public Health Action
https://www.readbyqxmd.com/read/28123964/evaluation-of-the-integrated-clinic-model-for-hiv-aids-services-in-ho-chi-minh-city-viet-nam-2013-2014
#19
V Hung, S T Nguyen, V T T Tieu, T T T Nguyen, T H Duong, S Lyss, J E Oeltmann
Setting: Ho Chi Minh City (HCMC), Viet Nam. Objective: To evaluate a new integrated service model for human immunodeficiency virus/acquired immune-deficiency syndrome (HIV/AIDS) care. Design: In HCMC, co-located services, including voluntary HIV counseling and testing (VCT), HIV treatment at out-patient clinics (OPC), and methadone maintenance therapy (MMT) for persons who inject drugs, have operated under different administrative structures. In the context of decreasing international financial support, integration of these services into one administrative structure with reduced staff occurred in seven districts in HCMC between October 2013 and June 2014...
December 21, 2016: Public Health Action
https://www.readbyqxmd.com/read/28123963/administrative-interventions-associated-with-increased-initiation-on-antiretroviral-therapy-in-irkutsk-siberia
#20
O B Ogarkov, A Ebers, S Zhdanova, E Moiseeva, M E Koshcheyev, E Zorkaltseva, S Shugaeva, S Vitko, G Lyles, E R Houpt, S K Heysell
A bundle of initiatives to integrate human immunodeficiency virus (HIV) and tuberculosis (TB) services was assessed for the impact on antiretroviral therapy (ART) initiation at a TB referral hospital in Irkutsk, Russian Federation, from February 2014 to December 2015. The ART initiation rates in 166 ART-naïve patients undergoing anti-tuberculosis treatment (34.1% with multidrug or extensively drug-resistant TB) increased significantly from 14 (17%) pre-intervention to 44 (54%) post-intervention (P < 0.001)...
December 21, 2016: Public Health Action
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