Read by QxMD icon Read

Canadian Journal of Gastroenterology & Hepatology

Tamara Milovanovic Alempijevic, Milica Stojkovic Lalosevic, Igor Dumic, Nevena Jocic, Aleksandra Pavlovic Markovic, Sanja Dragasevic, Ivana Jovicic, Snezana Lukic, Dragan Popovic, Tomica Milosavljevic
Objective: Keeping in mind the rising prevalence of nonalcoholic fatty liver disease (NAFLD) and the need to establish noninvasive tests for its detection, the aim of our study was to investigate whether platelet count (PC), mean platelet volume (MPV), and platelet distribution width (PDW) can predict the presence of liver fibrosis in this group of patients. Methods: In 98 patients with NAFLD and 60 healthy volunteers, complete blood counts with automated differential counts were performed and values of PC, PDW, MPV, and PCT were analyzed...
2017: Canadian Journal of Gastroenterology & Hepatology
Mahmud Mahamid, Omar Abu-Elhija, Tarik Yassin, William Nseir
[This corrects the article DOI: 10.1155/2017/2054871.].
2017: Canadian Journal of Gastroenterology & Hepatology
Vi Nguyen, Jiawei Li, Jaslyn Gan, Paul Cordero, Shuvra Ray, Alessandro Solis-Cuevas, Mai Khatib, Jude A Oben
Background: The incidence of nonalcoholic fatty liver disease (NAFLD) continues to parallel the rise in obesity rates. Endobariatric devices such as the intragastric balloon (IGB) may provide an alternative treatment option. Methods: Outcomes following IGB treatment in 135 patients with obesity and NAFLD (mean baseline weight 117.9 kg; BMI 41.7 kg/m 2 ; HOMA-IR 3.6) were retrospectively examined. Clinical, anthropometric, and biochemical changes were analysed at six months and after consecutive treatment with two and three serial IGBs...
2017: Canadian Journal of Gastroenterology & Hepatology
Xue Bing, Liu Xuelei, Dong Wanwei, Liang Linlang, Chen Keyan
Objective: To observe the protective effect of epigallocatechin gallate (EGCG) on dextran sulfate sodium- (DSS-) induced ulcerative colitis in rats and to explore the roles of TLR4/MyD88/NF-κB signaling pathway. Methods: Rat models of ulcerative colitis were established by giving DSS. EGCG (50 mg/kg/d) was given to assess disease activity index. HE staining was applied to observe histological changes. ELISA and qPCR detected the expression of inflammatory factors...
2017: Canadian Journal of Gastroenterology & Hepatology
Kianoosh Dadashzadeh, Maikel P Peppelenbosch, Akyala Ishaku Adamu
Background: Although the causal relationship between Helicobacter pylori infection and the development of gastric cancer is firmly established, the exact nature of the pathogenicity factors of H. pylori that predispose to gastric oncogenesis remains incompletely characterized. We investigated the association between H. pylori virulence genotypes and disease in a well-characterized cohort consisting of 109 H. pylori isolates from gastric biopsies originating from patients. Methods: The prevalence of genotype was assessed by PCR and related to clinical histopathological parameters...
2017: Canadian Journal of Gastroenterology & Hepatology
Thirumazhisai S Gunasekaran, Christopher Chu, Nemencio Ronquillo, Rohini Chennuri, Brian Adley, Kristina Borgen, Alan Schwartz, Robert Newberry, James Berman
EoE in children presents with four main symptoms. Most common symptoms exhibited by our clinic population are dysphagia (D) and abdominal pain (AP). Despite similar treatments, we found in an earlier study that the outcomes between these two groups were different. Therefore, we investigated if there exist any histological differences between these groups that could further our knowledge of EoE. Aim. To compare esophageal histology in detail, apart from the eosinophil count, between EoE-D and EoE-AP. Method...
2017: Canadian Journal of Gastroenterology & Hepatology
Davide Giuseppe Ribaldone, Giorgio Maria Saracco, Rinaldo Pellicano
No abstract text is available yet for this article.
2017: Canadian Journal of Gastroenterology & Hepatology
Majid Alsahafi, Paula Cramer, Nazira Chatur, Fergal Donnellan
Background: The inpatient status is a well-known risk factor for incomplete video capsule endoscopy (VCE) examinations due to prolonged transit time. We aimed to evaluate the effect of prucalopride on small bowel transit time for hospitalized patients undergoing VCE. Methods: We included all hospitalized patients who underwent VCE at a tertiary academic center from October 2011 through September 2016. A single 2 mg dose of prucalopride was given exclusively for all patients who underwent VCE between March 2014 and December 2015...
2017: Canadian Journal of Gastroenterology & Hepatology
Seogsong Jeong, Lei Gao, Ying Tong, Lei Xia, Ning Xu, Meng Sha, Jianjun Zhang, Xiaoni Kong, Jinyang Gu, Qiang Xia
Background: Prognostic impact of cirrhosis in patients with intrahepatic cholangiocarcinoma (ICC) upon hepatic resection remains unclear due to lack of studies in the literature. Methods: A total of 106 resected patients with ICC were reviewed, including 25 patients (23.6%) with cirrhosis and 81 noncirrhotic patients (76.4%). Subgroups of cirrhotic patients with and without hepatitis B virus (HBV) infection were studied. Results: The impact of cirrhosis on the overall survival (OS) (hazard ratio [HR], 0...
2017: Canadian Journal of Gastroenterology & Hepatology
Bin Zhang, Yu Pan, Ke Chen, Hendi Maher, Ming-Yu Chen, He-Pan Zhu, Yi-Bin Zhu, Yi Dai, Jiang Chen, Xiu-Jun Cai
Objective: To assess the feasibility, safety, and potential benefits of laparoscopy-assisted living donor hepatectomy (LADH) in comparison with open living donor hepatectomy (ODH) for liver transplantation. Background: LADH is becoming increasingly common for living donor liver transplant around the world. We aim to determine the efficacy of LADH and compare it with ODH. Methods: A systematic search on PubMed, Embase, Cochrane Library, and Web of Science was conducted in May 2017...
2017: Canadian Journal of Gastroenterology & Hepatology
Preya J Patel, David Smith, Jason P Connor, Leigh U Horsfall, Kelly L Hayward, Fabrina Hossain, Suzanne Williams, Tracey Johnson, Katherine A Stuart, Nigel N Brown, Nivene Saad, Andrew D Clouston, Katharine M Irvine, Anthony W Russell, Patricia C Valery, Elizabeth E Powell
Aim: To examine the association between lifetime alcohol consumption and significant liver disease in type 2 diabetic patients with NAFLD. Methods: A cross-sectional study assessing 151 patients with NAFLD at risk of clinically significant liver disease. NAFLD fibrosis severity was classified by transient elastography; liver stiffness measurements ≥8.2 kPa defined significant fibrosis. Lifetime drinking history classified patients into nondrinkers, light drinkers (always ≤20 g/day), and moderate drinkers (any period with intake >20 g/day)...
2017: Canadian Journal of Gastroenterology & Hepatology
Dawesh P Yadav, Saurabh Kedia, Kumble Seetharama Madhusudhan, Sawan Bopanna, Sandeep Goyal, Saransh Jain, Naval K Vikram, Raju Sharma, Govind K Makharia, Vineet Ahuja
Background: Results on body composition in Crohn's disease (CD) and ulcerative colitis (UC) have been heterogeneous and are lacking from Asia. Present study assessed body composition in CD/UC and correlated it with disease severity/duration. Methods: Patients of CD/UC following between Dec 2014 and Dec 2015 who consented for bioimpedance analysis for body fat measurement were included. Lean mass and fat-free mass index (FFMI) were calculated with standard formulae...
2017: Canadian Journal of Gastroenterology & Hepatology
Glynis Byrne, Greg Rosenfeld, Yvette Leung, Hong Qian, Julia Raudzus, Carlos Nunez, Brian Bressler
Background: Inflammatory bowel disease (IBD) patients are not routinely screened for depression and anxiety despite knowledge of an increased prevalence in people with chronic disease and negative effects on quality of life. Methods: Prevalence of anxiety and depression was assessed in IBD outpatients through retrospective chart review. The presence of anxiety and/or depression was determined using the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 self-report questionnaires or by diagnosis through psychiatric interview...
2017: Canadian Journal of Gastroenterology & Hepatology
Wandong Hong, Suhan Lin, Maddalena Zippi, Wujun Geng, Simon Stock, Zarrin Basharat, Bicheng Cheng, Jingye Pan, Mengtao Zhou
Background and Aims: To investigate the association between serum albumin levels within 24 hrs of patient admission and the development of persistent organ failure in acute pancreatitis. Methods: A total of 700 patients with acute pancreatitis were enrolled. Multivariate logistic regression and subgroup analysis determined whether decreased albumin was independently associated with persistent organ failure and mortality. The diagnostic performance of serum albumin was evaluated by the area under Receiver Operating Characteristic (ROC) curves...
2017: Canadian Journal of Gastroenterology & Hepatology
Tao Jiang, Zhao-Chong Zeng, Ping Yang, Yong Hu
Purpose: To evaluate the efficacy and safety of hypofractioned image-guided intensity modulated radiation therapy (IG-IMRT) for unresectable but confined intrahepatic hepatocellular carcinoma in comparison with conventional 3-dimensional conformal radiotherapy (3D-CRT). Methods: Ninety patients with unresectable but confined intrahepatic hepatocellular carcinoma without distant metastasis and tumor thrombosis received external beam radiation therapy. Of these patients, 45 received IG-IMRT and 45 received 3D-CRT...
2017: Canadian Journal of Gastroenterology & Hepatology
Bogdan Malkowski, Pawel Wareluk, Tomasz Gorycki, Katarzyna Skrobisz, Michal Studniarek
PURPOSE: (11)C-Acetate is radiotracer being considered an alternative to (18)F-fluorodeoxyglucose. Evaluation of (11)C-acetate biodistribution in human parenchymal organs is described. METHODS AND MATERIALS: 60 consecutive patients referred to (11)C-acetate PET CT suspected of renal or prostate cancer relapse with negative results (no recurrent tumor) were included in the study. Acquisition from the base of skull to upper thigh was made 20 min after i.v. injection of 720 MBq of (11)C-acetate...
2017: Canadian Journal of Gastroenterology & Hepatology
Lawrence Paszat, Rinku Sutradhar, Nancy N Baxter, Jill Tinmouth, Linda Rabeneck
BACKGROUND: The goal of this study is to examine utilization of early repeat colonoscopy ≤ 6 months after an index procedure. METHODS: We identified persons having repeat colonoscopy ≤ 6 months following outpatient colonoscopy without prior colonoscopy ≤ 5 years or prior diagnosis of colorectal cancer (CRC). We modeled repeat colonoscopy using a generalized estimating equation with an exchangeable correlation structure to account for clustering of patients by endoscopist...
2017: Canadian Journal of Gastroenterology & Hepatology
Mohammad Golriz, Maryam Ashrafi, Elias Khajeh, Ali Majlesara, Christa Flechtenmacher, Arianeb Mehrabi
BACKGROUND: Small for size syndrome (SFSS) is responsible for a high proportion of mortalities and morbidities following extended liver resection. AIM: The aim of this study was to establish a porcine model of SFSS. METHODS: Twenty-four Landrace pigs underwent liver resection with a remnant liver volume of 50% (group A, n = 8), 25% (group B, n = 8), and 15% (group C, n = 8). After resection, the animals were followed up for 8 days and clinical, laboratory, and histopathological outcomes were evaluated...
2017: Canadian Journal of Gastroenterology & Hepatology
Yan Hu, Xiaoting Chen, Xiaojing Chen, Shuang Zhang, Tianyan Jiang, Jing Chang, Yanhong Gao
OBJECTIVE: The purpose of this study was to evaluate the effect of bisphosphonates in improving bone mineral density (BMD) and decreasing the occurrence rate of fractures and adverse events in patients with inflammatory bowel disease (IBD). METHODS: Randomized controlled trials (RCTs) which use bisphosphonates in IBD patients were identified in PubMed, MEDLINE database, EMBASE database, Web of Knowledge, and the Cochrane Databases between 1990 and June 2016. People received bisphosphonate or placebos with a follow-up of at least one year were also considered...
2017: Canadian Journal of Gastroenterology & Hepatology
Matthew Cwinn, Gordon Walsh, Sheikh Hasibur Rahman, Michele Molinari
BACKGROUND: Studies on treatment modalities for primary hepatic neoplasms (PHN) in Canada are lacking. Our primary aim was to analyze the age-standardized incidence of hepatic resection, ablation, transplantation, and embolization for PHN between 2002 and 2013. Secondary aim was to evaluate temporal trends for these treatment modalities. STUDY DESIGN: National Canadian Cancer Registries were accessed for relevant epidemiological data. Age-standardized incidence of treatment ratios (SIRs) was calculated and comparisons were performed for Atlantic Canada, Ontario, the Prairies, and British Columbia...
2017: Canadian Journal of Gastroenterology & Hepatology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"