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South Asian Journal of Cancer

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https://www.readbyqxmd.com/read/29600240/neoadjuvant-chemotherapy-in-locally-advanced-invasive-lobular-carcinoma-a-limited-institutional-experience
#1
Ajay Gogia, Vinod Raina, S V S Deo, N K Shukla, Sandeep Mathur, D N Sharma
No abstract text is available yet for this article.
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600239/clinical-outcome-study-of-crizotinib-in-immunohistochemistry-proven-echinoderm-microtubule-associated-protein-like-4-anaplastic-lymphoma-kinase-fusion-gene-among-indian-patients-with-adenocarcinoma-lung
#2
Ullas Batra, Mohit Aggarwal, Parveen Jain, Pankaj Goyal, Abhishek Yadav, Udip Maheshwari, Anurag Mehta
Aims: The anaplastic lymphoma kinase (ALK) Break Apart FISH Probe Kit and Ventana anti-ALK (D5F3) CDx immunohistochemistry (IHC) assay are the Food and Drug Administration-approved companion diagnostic for targeted therapy with the ALK inhibitor crizotinib in lung cancers. The aim of this study was to assess the efficacy and safety of twice daily crizotinib tablet (250 mg) in IHC-proven echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion gene among Indian patients with adenocarcinoma lung in the routine clinical practice...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600238/efficacy-and-tolerability-of-bortezomib-and-dexamethasone-in-newly-diagnosed-multiple-myeloma
#3
Mir Sadaqat Hassan Zafar, Afaq Ahmed Khan, Shyam Aggarwal, Manorama Bhargava
Background: Outcome in multiple myeloma (MM) has improved substantially over recent years as a result of the availability of multiple novel agents with acceptable safety profile. Study Design: Prospective observational study at a tertiary care institute. Methods: Twenty-five newly diagnosed patients of MM were treated with bortezomib and dexamethasone induction with monitoring for response and safety, followed by peripheral blood autologous stem cell transplant (PBASCT) in eligible patients or maintenance...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600237/prospective-study-of-sequential-volumetric-changes-of-parotid-gland-in-early-oropharyngeal-carcinoma-patients-treated-by-intensity-modulated-radiation-therapy-an-institutional-experience
#4
Pooja Nandwani Patel, Sumit Goyal, Anand Shah, Mehul Gohel, Unnikrishnan Suryanarayana
Aims and Objectives: During course of radiation therapy, anatomical variations occur risking overdose of parotid gland. We tried to quantify volume of parotid gland and mean dose to parotid gland after every 10 fractions (#). Materials and Methods: We conducted the prospective study from July 2016 to May 2017 in 25 patients of early-stage oropharyngeal carcinoma. Patients had Karnofsy Performance Score of 80-100, median age was 54 years, and 18 patients were males...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600236/squamous-cell-carcinoma-of-buccal-mucosa-an-analysis-of-prognostic-factors
#5
Saurabh Bobdey, Jignasa Sathwara, Aanchal Jain, Sushma Saoba, Ganesh Balasubramaniam
Introduction: Carcinoma of the buccal mucosa is the most common oral cavity cancer in the Indian subcontinent. The aim of this study was to analyze the outcome and evaluate prognostic factors in surgically treated buccal mucosa squamous cell carcinoma (BMSCC) patients. Materials and Methods: A retrospective study was performed by reviewing the medical records of 409 pathologically proven buccal mucosa cancer patients, who were diagnosed and surgically treated in Tata Memorial Hospital between January 1, 2006, and December 31, 2008...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600235/assessment-of-oral-mucositis-during-concurrent-chemoradiation-of-head-and-neck-cancers-using-patient-reported-measurement-scale
#6
Nallan Csk Chaitanya, Arvind Muthukrishnan, P Karunakar, Manchala Himani, Neeharika Satya Jyothi Allam, Neha Jain
Introduction: Oral mucositis (OM) is a major challenge encountered in concurrent radiochemotherapy for the treatment of head and neck cancers. The patient reported OM symptoms scale (PROMS) was administered on these patients. The objective was to develop the similar scale in an Indian language and prescribe it population undergoing cancer treatment. Materials and Methods: PROMS scale was converted to Telugu language. Fifty-one patients took part in the study. All of them answered the 10-point questions marked their responses on 100 mm visual analog scale after thorough oral examination using WHO grading by the same examiner...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600234/prophylactic-salpingectomy-and-ovarian-cancer-an-evidence-based-analysis
#7
Tricia Dewi Anggraeni, Adly Nanda Al Fattah, Raymond Surya
Introduction: One of the ovarian carcinogenesis theories was the presence of premalignant cells in the epithelium of the fallopian tube. Therefore, the prophylactic salpingectomy during benign gynecological surgery is now expected as the attempt to reduce the ovarian cancer incidence. We studied the effect of prophylactic bilateral salpingectomy (PBS) in reducing the ovarian cancer incidence. Methods: This evidence-based report resulted from critical appraisal of 5 articles...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600233/translation-and-validation-of-european-organization-for-research-and-treatment-for-cancer-quality-of-life-questionnaire-ov-28-module-into-indian-languages-hindi-and-marathi-to-study-quality-of-life-of-ovarian-cancer-patients-from-a-tertiary-care-cancer-center
#8
Jyoti Bajpai, Pankaj Kumar Panda, Shraddha Kagwade, Madhavi Govilkar, Shruti Velaskar, Yogesh Kembhavi, Sudeep Gupta, Jaya Ghosh, Jayita Deodhar
Aim: The aim is to translate and validate the European Organization for Research and Treatment for Cancer (EORTC) ovarian cancer (OC) module (OV-28) into Hindi and Marathi to use for patients and scientific community. Methods and Results: The EORTC OV-28 was translated into Hindi and Marathi languages using prescribed guidelines by the EORTC. The process included forward translation by four translators (2 each for Hindi and Marathi). The questionnaires obtained were then given to independent backward-translators who then translated them back into English...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600232/geographical-distribution-of-cervical-cancer-in-odisha-a-5-year-retrospective-study-at-a-regional-cancer-center
#9
Pradeep Kumar Hota, Niharika Panda, Bhagyalaxmi Nayak, Sagarika Samantaray
Background: Cancer cervix and breast are the two major female health problems in India. A hospital-based, 5-year (2010-2014) retrospective study was conducted at a regional cancer center of Odisha to analyze the present burden of cancer cervix in this state, which has a population of more than 45.5 million at present. Materials and Methods: All the patients suffering from cancer cervix that was treated by radiotherapy during 2010-2014 at this center were analyzed year wise for age, stage of disease, and native area...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600231/outcomes-of-carcinosarcoma-in-a-tertiary-care-institution-in-india
#10
Anne George Cherian, Anitha Thomas, Ajit Sebastian, Tunny Sebastian, Vinotha Thomas, Rachel G Chandy, Abraham Peedicayil
Background: Carcinosarcoma is a rare malignancy, and reports are often mixed along with other sarcomas. The literature on uterine carcinosarcoma per se is sparse. Aims: This study aims to evaluate the demography, survival, and optimal treatment strategy of uterine carcinosarcoma. Settings and Design: A tertiary care center in India. The study design was descriptive with survival analysis. Materials and Methods: The medical records of all 18 patients admitted with uterine carcinosarcoma between January 2011 and December 2015 were reviewed...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600230/standard-dose-versus-high-dose-radiotherapy-with-concurrent-chemotherapy-in-esophageal-cancer-a-prospective-randomized-study
#11
Navin Nayan, M Bhattacharyya, Vikas K Jagtap, A K Kalita, R Sunku, P S Roy
Objective: The objective of this study is comparision of local and distant control rates with high-dose versus standard-dose radiotherapy along with concurrent chemotherapy in esophageal cancer - a prospective randomized study. Materials and Methods: Histologically proven Stage I-III patients with carcinoma esophagus were randomized into two groups. One group has been treated with standard-dose radiotherapy, i.e., a total dose of 50.4 Gy (1.8 Gy/day, 28#, 5 days/week)...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600229/epidemiology-of-liver-cancer-in-nile-delta-over-a-decade-a-single-center-study
#12
Sherief Abd-Elsalam, Nadia Elwan, Hanan Soliman, Dina Ziada, Walaa Elkhalawany, Marwa Salama, Nehad Hawash, Mona Arafa, Rehab Badawi, Walaa M Shehata, Haidy S Khalil, Nehal Elmashad
Background: In Egypt, there has been a remarkable increase in the proportion of hepatocellular carcinoma (HCC) among chronic liver diseases patients. This rising proportion may be explained by the increasing risk factors as hepatitis C virus (HCV) infection, hepatitis B virus (HBV) infection, improvement of the diagnostic tools of HCC as well as the extended survival among patients with cirrhosis to allow time for some of them to develop HCC. The aim of this study was to study the epidemiology of HCC in Nile delta over the last decade...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600228/incidental-gallbladder-carcinoma-utility-of-histopathological-evaluation-of-routine-cholecystectomy-specimens
#13
Vidya Jha, Preeti Sharma, K Ashish Mandal
Background: Incidental gallbladder carcinoma (IGBC) is rare cancer diagnosed during or after cholecystectomy done for benign gallbladder disease. The concern whether routine histopathological examination is needed for all cholecystectomy specimens still remains debatable. Materials and Methods: Twenty patients diagnosed with IGBC over a period of 2 years were retrospectively reviewed. Clinical details including clinical presentation, preoperative ultrasound (USG) findings, and macroscopic features were retrieved...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600227/pulmonary-artery-pseudoaneurysm-secondary-to-metastatic-breast-cancer
#14
Pey Ling Shum, Brian Ngo, Xiao Chen, Robert Jarvis
No abstract text is available yet for this article.
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600226/assessment-of-quality-of-life-in-resectable-gastric-cancer-patients-undergoing-chemoradiotherapy-as-adjuvant-treatment
#15
Deep Shankar Pruthi, Mushtaq Ahmad, Meenu Gupta, Saurabh Bansal, Vipul Nautiyal, Sunil Saini
Introduction: Quality of life (QOL) is increasingly recognized as an important endpoint in cancer therapies. However, few data are available on QOL in patients who have received radiotherapy as adjuvant treatment for cancer stomach. Methods: Thirty patients who underwent curative resection were enrolled and received chemoradiotherapy (45 Gy in 25 fractions using three-dimensional conformal radiotherapy technique), together with 5-fluorouracil and leucovorin. The European Organization for Research and Treatment of Cancer QOL questionnaire C30 and STO Q22 was assessed at four time points: pre- and postchemoradiotherapy and at 1-month and 6-month follow-up...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600225/comparison-of-health-related-quality-of-life-with-epirubicin-cisplatin-plus-5-fluorouracil-and-docetaxel-cisplatin-plus-5-fluorouracil-chemotherapy-regimens-as-first-line-systemic-therapy-in-locally-advanced-inoperable-or-metastatic-gastric-or-gastro-esophageal
#16
K Govind Babu, Tamojit Chaudhuri, K C Lakshmaiah, Lokanatha Dasappa, Linu Abraham Jacob, M C Suresh Babu, A H Rudresha, K N Lokesh, L K Rajeev
Background: Health-related quality of life (HRQOL) is an important oncologic end point for upper gastrointestinal malignancies. Unfortunately, till date, there is no published prospective data from India, comparing the HRQOL parameters between first-line chemotherapy regimens in advanced/metastatic gastric cancer. Materials and Methods: The present study aimed to compare the HRQOL of first-line systemic chemotherapy with epirubicin, cisplatin plus 5-FU (ECF) and docetaxel, cisplatin plus 5-FU (DCF) regimens in patients with locally advanced inoperable or metastatic gastric or gastro-esophageal junction adenocarcinoma...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600224/estrogen-receptor-progesterone-receptor-and-human-epidermal-growth-factor-receptor-2-status-in-breast-cancer-a-retrospective-study-of-5436-women-from-a-regional-cancer-center-in-south-india
#17
Rekha Vijay Kumar, Dipti Panwar, Usha Amirtham, Chennagiri Srinivasmurthy Premalata, Champaka Gopal, Suma Mysore Narayana, Geetha Vikram Patil Okaly, K C Lakshmaiah, S Krishnamurthy
Aim: The aim of the study was to analyze the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) status over 7 years in South Indian women with breast cancer. Further analysis of a subgroup was done to study clinically defined subtypes and the role of preanalytical factors in needle core biopsies (NCBs) and excised specimens. Materials and Methods: This was a retrospective study from January 2010 to December 2016...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600223/estrogen-receptor-and-progesterone-receptor-status-of-breast-cancer-patients-of-eastern-india-a-multi-institutional-study
#18
Koushik Chatterjee, Gautam Bhaumik, Bhargab Chattopadhyay
Context: There is a paucity of any significant data on the estrogen receptor (ER) and progesterone receptor (PR) status of breast cancer patients from the eastern part of India. Aims: This study aims to document the ER and PR status of breast cancer patients in the eastern Indian population, as catered by two premier tertiary care hospitals in Kolkata. Subjects and Methods: All breast cancer patients registered between January 1, 2013 and December 31, 2015, in the Departments of Oncology, of IPGMER and SSKM Hospitals and R...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600222/a-large-cystic-gastrointestinal-stromal-tumor-within-lesser-sac-a-diagnostic-dilemma
#19
Anup Sunil Tamhankar, Tanuja Anup Tamhankar
No abstract text is available yet for this article.
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29600221/prognostic-factors-and-outcomes-in-anaplastic-gliomas-an-institutional-experience
#20
Deepthi Valiyaveettil, Monica Malik, Deepa Joseph, Syed Fayaz Ahmed, Syed Akram Kothwal
Background: There is lack of clear evidence and treatment guidelines for anaplastic gliomas (AGs) with very few studies focusing exclusively on these patients. The aim of the study was to analyze the clinical profile and survival in these patients. Materials and Methods: Patients of AGs treated with radiation and concurrent ± adjuvant chemotherapy from January 2010 to December 2015 were analyzed. Statistical analysis was done using SPSS version 20 software. Results: A total of 100 patients were included in the study...
January 2018: South Asian Journal of Cancer
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