journal
MENU ▼
Read by QxMD icon Read
search

Frontiers in Pediatrics

journal
https://www.readbyqxmd.com/read/30109220/carbonic-anhydrase-ii-deficiency-a-rare-case-of-severe-obstructive-sleep-apnea
#1
Emanuela di Palmo, Marcella Gallucci, Elena Tronconi, Rosalba Bergamaschi, Salvatore Cazzato, Claudio La Scola, Giampaolo Ricci, Andrea Pession
The term osteopetrosis describes a group of rare hereditary diseases of the skeleton, characterized by an increase in bone density, caused by a defect in the development or function of osteoclasts. It comprises a clinically and genetically heterogeneous conditions ranging from infantile onset life-threatening forms to mildest adult onset forms. "Malignant" osteopetrosis is characterized by bone fragility, short stature, compressive neuropathies, hypocalcaemia, pancytopaenia. The deficiency of carbonic anhydrase II causes a moderate form, presenting classically as a triad of osteopetrosis, renal tubular acidosis (RTA), and cerebral calcification...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30109219/editorial-pediatric-hypertension-update
#2
EDITORIAL
Ibrahim F Shatat, Tammy M Brady
No abstract text is available yet for this article.
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30105222/editorial-extra-corporeal-membrane-oxygenation-in-pediatric-cardiac-patients
#3
EDITORIAL
Antonio F Corno, Tara Karamlou
No abstract text is available yet for this article.
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30101141/incomplete-refractory-kawasaki-disease-in-an-infant-a-case-report-and-a-review-of-the-literature
#4
Cristina O Mărginean, Lorena E Meliț, Liliana Gozar, Cristian Dan Mărginean, Maria O Mărginean
Kawasaki disease (KD) is a febrile vasculitis, which is commonly defined by fever and at least four specific clinical symptoms. Incomplete KD is defined by suggestive echocardiographic findings with an incomplete clinical picture. Refractory KD is diagnosed in patients resistant to intravenous immunoglobulin (IVIG). We report the case of a 6-month-old male infant admitted to our clinic for persistent fever and onset of a generalized polymorphous rash, accompanied by high fever, rhinorrhea, and cough for the past 7 days...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30087887/disparities-in-utilization-of-social-determinants-of-health-referrals-among-children-in-immigrant-families
#5
Omolara T Uwemedimo, Hanna May
Objective: Children in immigrant families (CIF) are at elevated risk of experiencing adverse social determinants of health (SDH), particularly material hardship, which contribute to disparate health outcomes. Previous studies have found that SDH screening programs integrated into pediatric practices have increased receipt of social service resources. Few studies have examined use of social services in these programs among ethnically-diverse patient populations and associations with caregiver immigrant status or limited English proficiency (LEP)...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30073157/comics-as-a-medium-for-parent-health-education-improving-understanding-of-normal-9-month-old-developmental-milestones
#6
Eduardo D Rosas-Blum, Hector M Granados, Brandy W Mills, Marie Leiner
Multimodal literacy, a product of modern technology, can aid in the recall of simple-to-complex information for both children and adults. Health education information presented using educational comics takes advantage of multimodal formats and designs based on theoretical models of learning. In this study, we utilized a quasi-experimental design with both pre- and post-intervention testing. The parents of every other patient that attended the well-child appointments of their child aged <9 months were invited to participate in this study...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30073156/immunomodulation-to-prevent-or-treat-neonatal-sepsis-past-present-and-future
#7
REVIEW
Simone S Schüller, Boris W Kramer, Eduardo Villamor, Andreas Spittler, Angelika Berger, Ofer Levy
Despite continued advances in neonatal medicine, sepsis remains a leading cause of death worldwide in neonatal intensive care units. The clinical presentation of sepsis in neonates varies markedly from that in older children and adults, and distinct acute inflammatory responses results in age-specific inflammatory and protective immune response to infection. This review first provides an overview of the neonatal immune system, then covers current mainstream, and experimental preventive and adjuvant therapies in neonatal sepsis...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30065917/cantrell-syndrome-a-rare-complex-congenital-anomaly-a-case-report-and-literature-review
#8
Claudiu Mărginean, Cristina Oana Mărginean, Liliana Gozar, Lorena Elena Meliţ, Horaţiu Suciu, Horea Gozar, Andrada Crişan, Manuela Cucerea
Cantrell syndrome (CS) or pentalogy of Cantrell is defined as a rare condition involving a midline anterior abdominal wall defect, a distal sternal cleft, a defect of the anterior diaphragm, and a defect of the apical pericardium with pericardio-peritoneal communication, as well as intracardiac anomalies. We report the case of a male newborn with type 2 CS diagnosed during intrauterine life based on ultrasonographic evaluation. Clinical examination at birth revealed an abdominal wall defect with extrathoracic displacement of the heart and a diastasis of the sagittal suture...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30065916/exploring-the-clinical-and-genetic-spectrum-of-steroid-resistant-nephrotic-syndrome-the-podonet-registry
#9
REVIEW
Agnes Trautmann, Beata S Lipska-Ziętkiewicz, Franz Schaefer
Background: Steroid resistant nephrotic syndrome (SRNS) is a rare condition, accounting for 10-15% of all children with idiopathic nephrotic syndrome. SRNS can be caused by genetic abnormalities or immune system dysfunction. The prognosis of SRNS varies from permanent remission to progression to end-stage kidney disease, and post-transplant recurrence is common. Objectives: The PodoNet registry project aims to explore the demographics and phenotypes of immune-mediated and genetic forms of childhood SRNS, to assess genotype-phenotype correlations, to evaluate clinical management and long-term outcomes, and to search for novel genetic entities and diagnostic and prognostic biomarkers in SRNS...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30062090/prevalence-of-hearing-impairment-among-high-risk-newborns-in-ibadan-nigeria
#10
Adeyemi A Labaeka, Olukemi O Tongo, Babatunde O Ogunbosi, James A Fasunla
The burden of severe hearing impairment is increasing with two-thirds of these hearing impaired people residing in developing countries. Newborn hearing screening helps to identify early, babies who need intervention in order to prevent future disability. Neither universal nor targeted hearing screening programme is available in Nigeria. Objectives: This study was carried out to assess the prevalence of hearing impairment among high-risk newborns in UCH and the associated risk factors. Materials and Methods: Two hundred one newborns in the neonatal unit of UCH with risk factors for hearing impairment had hearing screening done using automated auditory brainstem response (AABR) at 30, 45, and 70 dB at admission and discharge, and those that failed screening at discharge were rescreened at 6 weeks post-discharge...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30057894/experimental-models-to-study-podocyte-biology-stock-taking-the-toolbox-of-glomerular-research
#11
REVIEW
Henning Hagmann, Paul T Brinkkoetter
Diseases affecting the glomeruli of the kidney, the renal filtration units, are a leading cause of chronic kidney disease and end-stage renal failure. Despite recent advances in the understanding of glomerular biology, treatment of these disorders has remained extraordinarily challenging in many cases. The use of experimental models has proven invaluable to study renal, and in particular, glomerular biology and disease. Over the past 15 years, studies identified different and very distinct pathogenic mechanisms that result in damage, loss of glomerular visceral epithelial cells (podocytes) and progressive renal disease...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30042935/kawasaki-disease
#12
REVIEW
Christian M Hedrich, Anja Schnabel, Toni Hospach
Kawasaki disease (KD) is an acute-onset systemic vasculitis of medium-sized vessels that mostly affects infants and toddlers. Globally, it is the most common form of childhood primary vasculitis. Delayed diagnosis and treatment results in coronary artery aneurysms in up to 25% of all affected individuals. Thus, KD is the most common acquired heart disease in developed countries. Here, the current understanding of clinical presentations, pathophysiological concepts, disease-associated complications, and available pharmaceutical treatment is provided and discussed in the context of available literature...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30042934/successful-resuscitation-in-a-model-of-asphyxia-and-hemorrhage-to-test-different-volume-resuscitation-strategies-a-study-in-newborn-piglets-after-transition
#13
Marc R Mendler, Stephan Schwarz, Lisbeth Hechenrieder, Steven Kurth, Birte Weber, Severin Höfler, Miriam Kalbitz, Benjamin Mayer, Helmut D Hummler
Background: Evidence for recommendations on the use of volume expansion during cardiopulmonary resuscitation in newborn infants is limited. Objectives: To develop a newborn piglet model with asphyxia, hemorrhage, and cardiac arrest to test different volume resuscitation on return of spontaneous circulation (ROSC). We hypothesized that immediate red cell transfusion reduces time to ROSC as compared to the use of an isotonic crystalloid fluid. Methods: Forty-four anaesthetized and intubated newborn piglets [age 32 h (12-44 h), weight 1,220 g (1,060-1,495g), Median (IQR)] were exposed to hypoxia and blood loss until asystole occurred...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30042933/pulmonary-regurgitation-is-the-future-percutaneous-or-surgical
#14
REVIEW
Gareth J Morgan
For decades, surgical replacement of the pulmonary valve has been seen as the gold-standard technique. Until the advent of Medtronic's Melody valve, it was the only option. Whilst radical changes in surgical techniques have not been forthcoming, rapid and substantial developments in the techniques and available technology for percutaneous valves now cause us to ask if the gold-standard moniker now belongs in the cath lab. This manuscript explores the recent history and future of a revolution in this large area of congenital cardiac practice...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30035104/measuring-airway-inflammation-in-asthmatic-children
#15
REVIEW
Laura Tenero, Marco Zaffanello, Michele Piazza, Giorgio Piacentini
Asthma is the most common chronic respiratory disease in children characterized by airways inflammation, bronchial hyperresponsiveness, recurrent reversible airways obstruction, and respiratory symptoms. The diagnosis of the disease is based on clinical history, airways obstruction at spirometry, and bronchial reversibility. Asthma treatment is aimed to disease control, through the use of controller treatment and monitoring lung function. However, lung function and symptoms not always reflect the underlying airways inflammation and response to the therapy...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30035103/predicting-body-height-in-a-pediatric-intensive-care-unit-using-ulnar-length
#16
Melody A Rasouli, Christopher J L Newth, Robinder G Khemani, Patrick A Ross
Objective: To determine if ulnar length obtained by the bedside nurse can be used to estimate patient length. To compare our findings to previous predictive equations of height and ulnar length. To evaluate the performance of predictive equations for height and ulnar length on patients with syndromes that affect height. Design: Retrospective observational study of prospectively collected data. Settings: Multidisciplinary Pediatric Intensive Care Unit in a university teaching hospital. Patients: 1,177 patients, ages 1 month to 23 years...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30023355/growth-mindset-moderates-the-effect-of-the-neonatal-resuscitation-program-on-performance-in-a-computer-based-game-training-simulation
#17
Maria Cutumisu, Matthew R G Brown, Caroline Fray, Georg M Schmölzer
This study examines for the first time the moderating role of growth mindset on the association between the time elapsed since participants' last refresher neonatal resuscitation program (NRP) course and their performance on neonatal resuscitation tasks in the RETAIN computer game training simulation. Participants were n = 50 health-care providers affiliated with a large university hospital. Results revealed that growth mindset moderated the relation between participants' task performance in the game and the time since their latest refresher NRP course...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30018948/the-shisong-cardiac-center-in-cameroon-an-example-of-a-long-term-collaboration-cooperation-toward-autonomy
#18
Alessandro Giamberti, Gianfranco Butera, Charles Mve Mvondo, Silvia Cirri, Alessandro Varrica, Nadia Moussaidi, Giuseppe Isgrò, Jean Claude Ambassa, Cabral Tantchou, Giovanni Giamberti, Alessandro Frigiola
Congenital heart diseases (CHD) are present in nearly 1% of live births; according to WHO, there are 1. 5 million newborns affected by CHD per year and more than 4 million children waiting for cardiac surgery treatment worldwide. The majority of these children (~90%) could be treated, saved and subsequently have a good quality of life but unfortunately, in developing countries with a suboptimal care or no access to care, they are destined to die. Cameroon, one of the 40 poorest countries in the world, is a typical example of this dramatic scenario and this is why we started a collaboration project with a local religious partner (Tertiary Sisters of Saint Francis) in 2001 with the aim of establishing the first cardiac surgery center in this country...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30018947/vesicoamniotic-shunting-improves-outcomes-in-a-subset-of-prune-belly-syndrome-patients-at-a-single-tertiary-center
#19
Jeffrey T White, Kunj R Sheth, Aylin E Bilgutay, David R Roth, Paul F Austin, Edmond T Gonzales, Nicolette K Janzen, Duong D Tu, Angela G Mittal, Chester J Koh, Sheila L Ryan, Carolina Jorgez, Abhishek Seth
Objective: Review outcomes of Prune Belly Syndrome (PBS) with the hypothesis that contemporary management improves mortality. Methods: A retrospective chart review of inpatient and outpatient PBS patients referred between 2000 and 2018 was conducted to assess outcomes at our institution. Data collected included age at diagnosis, concomitant medical conditions, imaging, operative management, length of follow-up, and renal function. Results: Forty-five PBS patients presented during these 18 years. Prenatal diagnoses were made in 17 (39%); 65% of these patients underwent prenatal intervention...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30013962/hhv-6-specific-t-cell-immunity-in-healthy-children-and-adolescents
#20
Christine M Schwarz, Volker Strenger, Heimo Strohmaier, Georg Singer, Margarita Kaiser, Andrea Raicht, Wolfgang Schwinger, Christian Urban
Objective: Primary infection with human herpes virus 6 (mainly HHV-6B) commonly occurs in the first 2 years of life leading to persistence and the possibility of virus reactivation later in life. Consequently, a specific cellular immune response is essential for effective control of virus reactivation. We have studied cell-mediated immune response to HHV-6 (U54) in healthy children and adolescents. Materials and Methods: By flow cytometry, the amount of cytokine (interferon gamma-IFN- γ, interleukin 2-IL-2, tumor necrosis factor alpha-TNF-α) secreting T-cells were measured after 10 days of pre-sensitization and 6 h of re-stimulation with mixtures of pooled overlapping peptides from U54, staphylococcal enterotoxin B (SEB, positive control), or Actin (negative control) in healthy children and adolescents without any underlying immune disorder or infectious disease...
2018: Frontiers in Pediatrics
journal
journal
48236
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"