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Global Cardiology Science & Practice

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https://www.readbyqxmd.com/read/30083548/cardiac-amyloidosis-the-great-masquerader
#1
Jubran Rind, Nagib Chalfoun, Richard McNamara
Cardiac amyloidosis is an elusive condition that is notorious for mimicking various cardiovascular conditions that present with left ventricular hypertrophy (LVH). The hypertrophy in amyloidosis is typically diffuse; however, rare reports of echocardiographic resemblances with hypertrophic cardiomyopathy (HCM) exist, such as asymmetric septal hypertrophy and left ventricular outflow tract obstruction. Cardiac MRI can help differentiate amyloidosis from hypertrophic cardiomyopathy in unclear situations. This differentiation from HCM and other forms of cardiomyopathy has important treatment implications...
June 30, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/30083547/cerebral-hemorrhagic-infarction-as-the-initial-manifestation-of-deep-venous-thrombosis-in-a-child-with-patent-foramen-ovale
#2
Dimitrios Panagopoulos, Sofia Loukopoulou, Evagelos Karanasios, Georgia Grigoriadou, Nikolaos Eleftherakis
Arterial ischemic stroke (AIS), with an estimated incidence of 1.1-4.3 per 100,000, is an important cause of morbidity and mortality in children and the risk of recurrence is high. We present the case of an 11-year-old child who presented with a symptomatology of acute ischemic stroke of unknown etiology. The radiological investigation did not reveal any underlying brain abnormality that could cause the event. The diagnostic work up included an echocardiogram, which revealed a thrombus in the right atrium, in conjunction with a patent foramen ovale...
June 30, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/30083546/massive-transient-pulmonary-air-embolism-during-permanent-cardiac-pacemaker-implantation
#3
Emre Ozdemir, Fatma Kayaalti Esin, Cem Nazli
Pulmonary air embolism is a rare complication with a high probability of death. We present an air embolism case during permanent cardiac pacemaker implantation procedure. When the patient worsened hemodynamically, we saw a large air embolism in the main pulmonary trunk. Air embolism can be fatal, it is always iatrogenic, but is an avoidable complication.
June 30, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/30083545/heparin-induced-thrombocytopenia-hit-identification-and-treatment-pathways
#4
REVIEW
Mahmoud Fathi
Heparin-induced thrombocytopenia (HIT) is a major health problem, especially in cardiac surgery theaters, cardiac catheterization labs, and intensive care units. Some patients with HIT develop serious thrombotic complications like limb ischemia and gangrene, while others may not develop such complications and have only mild thrombocytopenia. Current laboratory diagnostic tools incur significant time delays before confirming HIT, therefore upon clinical suspicion, treatment of HIT should start immediately while awaiting laboratory results...
June 30, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/30083544/macrophage-migration-inhibitory-factor-mif-in-the-development-and-progression-of-pulmonary-arterial-hypertension
#5
REVIEW
Mohamed Ahmed, Edmund Miller
Macrophage migration inhibitory factor (MIF) has been described as a pro-inflammatory cytokine and regulator of neuro-endocrine function. It plays an important upstream role in the inflammatory cascade by promoting the release of other inflammatory cytokines such as TNF-alpha and IL-6, ultimately triggering a chronic inflammatory immune response. As lungs can synthesize and release MIF, many studies have investigated the potential role of MIF as a biomarker in assessment of patients with pulmonary arterial hypertension (PAH) and using anti-MIFs as a new therapeutic modality for PAH...
June 30, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/30083543/the-north-karelia-project-cardiovascular-disease-prevention-in-finland
#6
REVIEW
Erkki Vartiainen
The extremely high cardiovascular mortality in an eastern province North Karelia in Finland caused great concern among the local population. Action to reduce the problem was demanded in a petition to the Finnish government signed by local representatives of the population. In response, the North Karelia project was launched in 1972 to carry out a comprehensive community based prevention program. After the first five years, prevention activities were also started nationally. The main aim was to reduce the extremely high serum cholesterol, blood pressure and smoking levels with lifestyle changes and improved drug treatment, especially for hypertension...
June 30, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/30083542/a-systematic-approach-to-3d-echocardiographic-assessment-of-the-aortic-root
#7
REVIEW
Andreas Hagendorff, Stephan Stoebe, Bhupendar Tayal
No abstract text is available yet for this article.
June 30, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/30083541/christiaan-barnard-the-surgeon-who-dared-the-story-of-the-first-human-to-human-heart-transplant
#8
REVIEW
David K C Cooper
In 2017, we celebrated the 50th anniversary of the first human heart transplant that had been carried out by the South African surgeon, Christiaan ('Chris') Barnard at Groote Schuur Hospital in Cape Town on December 3rd , 1967. The daring operation and the charismatic surgeon received immense public attention around the world. The patient's progress was covered by the world's media on an almost hourly basis. Although the patient, Mr. Louis Washansky, died after only 18 days, Barnard soon carried out a second transplant, and this patient led an active life for almost 19 months...
June 30, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/30083540/heart-transplantation-at-50-celebrations-and-challenges
#9
EDITORIAL
Magdi Yacoub, Asghar Khaghani
No abstract text is available yet for this article.
June 30, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644236/hypertrophic-cardiomyopathy-with-a-large-apical-ventricular-aneurysm-and-mural-thrombus
#10
Munis Raza, Nagib Chalfoun, Abdallah Wissam, Hamza Hashmi, Richard McNamara
Hypertrophic cardiomyopathy (HCM) is characterized by increased left ventricular wall thickness in the absence of any other identifiable cause of thickness. It predisposes the patient to increased risk of sudden cardiac death (SCD) due to fatal arrhythmias. Approximately 2% of the HCM patients have left ventricular apical aneurysm. CMR imaging is better in identifying this apical aneurysm as compared to echocardiogram. This apical aneurysm, which can be akinetic or dyskinetic, increases the risk of disease-related adverse events as compared to general HCM...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644235/endograft-rescue-of-compromised-interposition-aortic-graft-in-an-adult-patient-with-congenital-heart-disease
#11
Jesse W Lee, Kanishka Ratnayaka, Howaida G El-Said, John W Moore
In a 19-year-old male with interrupted aortic arch and complex congenital heart disease, we report percutaneous repair of a compromised aortic conduit. The patient had aortic arch repair in childhood utilizing a 12 mm Hemashield Dacron conduit. CT angiography showed multiple segments of this conduit were dilated to 16 mm suggesting conduit degeneration and failure with pseudoaneurysm formation. We utilized a self-expanding aortic endograft supported by internal placement of bare metal stents to repair the conduit...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644234/modelling-coronary-flow-after-the-norwood-operation-influence-of-a-suggested-novel-technique-for-coronary-transfer
#12
Mohammed K Al-Jughiman, Maryam A Al-Omair
Background: The dynamic behavior of the aortic sinuses has an important function in the specific characteristics of coronary blood flow. Several publications have confirmed suboptimal myocardial perfusion after the Norwood procedure. Our study was undertaken to confirm four hypotheses. First, we hypothesized that there is more resistance to coronary flow due to coronary attachments to hypoplastic aortic root and sinuses. Also, as the amalgamation of the ascending aorta with the pulmonary artery occurs above the aortic root, the coronary blood flow is not fully in antegrade pattern...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644233/prevalence-awareness-treatment-control-and-risk-factors-associated-with-hypertension-in-lebanese-adults-a-cross-sectional-study
#13
Bouchra Bakr Mouhtadi, Reem Mohamad Najib Kanaan, Mohammad Iskandarani, Mohamad Khaled Rahal, Dalal Hammoudi Halat
Background: The prevention and control of hypertension is an essential component for reducing cardiovascular disease burden. Hypertension is an important public health issue, yet few studies have examined its current status among the Lebanese population. Objective: To examine the prevalence, awareness, treatment and control of hypertension and its associated risk factors among Lebanese adults. Methods: A cross-sectional study was conducted between December 2014, and May 2015, on adults from the five districts of Lebanon...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644232/individualizing-immunosuppression-in-lung-transplantation
#14
REVIEW
Jennifer K McDermott, Reda E Girgis
Immunosuppression management after lung transplantation continues to evolve, with an increasing number of agents available for use in various combinations allowing for more choice and individualization of immunosuppressive therapy. Therapeutic developments have led to improved outcomes including lower acute rejection rates and improved survival. However, a one size fits all approach for any immunosuppressive strategy may not be best suited to the individual patient and ultimately patient specific factors must be considered when designing the immunosuppressive regimen...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644231/mechanistic-insights-of-the-left-ventricle-structure-and-fibrosis-in-the-arrhythmogenic-mitral-valve-prolapse
#15
REVIEW
Leticia Fernández-Friera, Rafael Salguero, Luca Vannini, Ana Fidalgo Argüelles, Fernando Arribas, Jorge Solís
Mitral valve prolapse (MVP) is a common and benign condition. However, some anatomic forms have been recently associated with life-threatening ventricular arrhythmias and sudden cardiac death. Imaging MVP holds the promise of individualized MVP risk assessment. Noninvasive imaging techniques available today are playing an increasingly important role in the diagnosis, prognosis and monitoring of MVP. In this article, we will review the current evidence on arrhythmogenic MVP, with special focus on the utility of echocardiography and CMR for identifying benign and "malignant" forms of MVP...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644230/noble-and-excel-the-debate-for-excellence-in-dealing-with-left-main-stenosis
#16
Hamood Al Kindi, Amir Samaan, Hatem Hosny
Left main coronary artery (LMCA) disease is associated with increased morbidity and mortality. Coronary artery bypass grafting surgery (CABG) has always been the standard revascularization strategy for this group of patients. However, with the recent developments in stents design and medical therapy over the past decade, several trials have been designed to evaluate the safety and efficacy of percutaneous coronary intervention (PCI) as an alternative to CABG surgery in patients with LMCA disease. Recently, the results of two major trials, EXCEL and NOBLE, comparing CABG versus PCI in this patient population have been released...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644229/cantos-a-breakthrough-that-proves-the-inflammatory-hypothesis-of-atherosclerosis
#17
Mohamed Hassan
Atherosclerosis is no longer considered solely a disorder of subintimal deposition of modified low-density lipoprotein particles in the arterial wall. Rather, it is known to be a chronic inflammatory disorder. No evidence has shown that reducing vascular inflammation in the absence of concomitant lowering of lipoproteins levels reduces the rates of adverse cardiovascular (CV) events. Canakinumab, a fully human monoclonal antibody that neutralizes interleukin (IL)-1β, significantly reduced the rate of recurrent CV events in patients with prior myocardial infarction in the Canakinumab Anti-inflammatory Thrombosis Outcome Study (CANTOS)...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644228/how-are-countries-dealing-with-their-current-cardio-vascular-disease-burden-a-snapshot-from-the-who-eastern-mediterranean-region-emr
#18
EDITORIAL
Asmus Hammerich
In recent years, a number of global commitments have been made in the area of noncommunicable diseases (NCD). These include the UN NCD Political Declaration in 2011, and the UN Comprehensive Review on NCDs and Outcome Document in 2014. Nine global targets have been agreed in the area of NCDs, and NCDs have been addressed in the Sustainable Development Goals (SDG). Another UN high-level meeting will take place in September 2018 to assess country progress across the globe. At the regional level, a number of initiates have taken place to deliver on these global commitments...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564353/pseudo-normalization-of-a-coronary-artery-aneurysm-detected-by-ivus
#19
Sherif Rizk, Waseem Amin, Hala Hamza, Karim Said, Galal El Said
No abstract text is available yet for this article.
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564352/management-of-sequelae-of-kawasaki-disease-in-adults
#20
REVIEW
John B Gordon, Jane C Burns
Background: A growing population of young adults is presenting to cardiologists with late manifestations of Kawasaki disease (KD) that include cardiomyopathy, ischemia, and infarction. The management of these conditions differs in important ways from atherosclerotic heart disease, and yet there is little awareness in the adult cardiology community regarding the special challenges posed by the cardiovascular sequelae of KD. Methods: Observations were made on a population of 140 adult KD patients enrolled in the San Diego Adult KD Collaborative Study...
October 31, 2017: Global Cardiology Science & Practice
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