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Global Cardiology Science & Practice

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https://www.readbyqxmd.com/read/29644236/hypertrophic-cardiomyopathy-with-a-large-apical-ventricular-aneurysm-and-mural-thrombus
#1
Munis Raza, Nagib Chalfoun, Abdallah Wissam, Hamza Hashmi, Richard McNamara
Hypertrophic cardiomyopathy (HCM) is characterized by increased left ventricular wall thickness in the absence of any other identifiable cause of thickness. It predisposes the patient to increased risk of sudden cardiac death (SCD) due to fatal arrhythmias. Approximately 2% of the HCM patients have left ventricular apical aneurysm. CMR imaging is better in identifying this apical aneurysm as compared to echocardiogram. This apical aneurysm, which can be akinetic or dyskinetic, increases the risk of disease-related adverse events as compared to general HCM...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644235/endograft-rescue-of-compromised-interposition-aortic-graft-in-an-adult-patient-with-congenital-heart-disease
#2
Jesse W Lee, Kanishka Ratnayaka, Howaida G El-Said, John W Moore
In a 19-year-old male with interrupted aortic arch and complex congenital heart disease, we report percutaneous repair of a compromised aortic conduit. The patient had aortic arch repair in childhood utilizing a 12 mm Hemashield Dacron conduit. CT angiography showed multiple segments of this conduit were dilated to 16 mm suggesting conduit degeneration and failure with pseudoaneurysm formation. We utilized a self-expanding aortic endograft supported by internal placement of bare metal stents to repair the conduit...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644234/modelling-coronary-flow-after-the-norwood-operation-influence-of-a-suggested-novel-technique-for-coronary-transfer
#3
Mohammed K Al-Jughiman, Maryam A Al-Omair
Background: The dynamic behavior of the aortic sinuses has an important function in the specific characteristics of coronary blood flow. Several publications have confirmed suboptimal myocardial perfusion after the Norwood procedure. Our study was undertaken to confirm four hypotheses. First, we hypothesized that there is more resistance to coronary flow due to coronary attachments to hypoplastic aortic root and sinuses. Also, as the amalgamation of the ascending aorta with the pulmonary artery occurs above the aortic root, the coronary blood flow is not fully in antegrade pattern...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644233/prevalence-awareness-treatment-control-and-risk-factors-associated-with-hypertension-in-lebanese-adults-a-cross-sectional-study
#4
Bouchra Bakr Mouhtadi, Reem Mohamad Najib Kanaan, Mohammad Iskandarani, Mohamad Khaled Rahal, Dalal Hammoudi Halat
Background: The prevention and control of hypertension is an essential component for reducing cardiovascular disease burden. Hypertension is an important public health issue, yet few studies have examined its current status among the Lebanese population. Objective: To examine the prevalence, awareness, treatment and control of hypertension and its associated risk factors among Lebanese adults. Methods: A cross-sectional study was conducted between December 2014, and May 2015, on adults from the five districts of Lebanon...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644232/individualizing-immunosuppression-in-lung-transplantation
#5
REVIEW
Jennifer K McDermott, Reda E Girgis
Immunosuppression management after lung transplantation continues to evolve, with an increasing number of agents available for use in various combinations allowing for more choice and individualization of immunosuppressive therapy. Therapeutic developments have led to improved outcomes including lower acute rejection rates and improved survival. However, a one size fits all approach for any immunosuppressive strategy may not be best suited to the individual patient and ultimately patient specific factors must be considered when designing the immunosuppressive regimen...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644231/mechanistic-insights-of-the-left-ventricle-structure-and-fibrosis-in-the-arrhythmogenic-mitral-valve-prolapse
#6
REVIEW
Leticia Fernández-Friera, Rafael Salguero, Luca Vannini, Ana Fidalgo Argüelles, Fernando Arribas, Jorge Solís
Mitral valve prolapse (MVP) is a common and benign condition. However, some anatomic forms have been recently associated with life-threatening ventricular arrhythmias and sudden cardiac death. Imaging MVP holds the promise of individualized MVP risk assessment. Noninvasive imaging techniques available today are playing an increasingly important role in the diagnosis, prognosis and monitoring of MVP. In this article, we will review the current evidence on arrhythmogenic MVP, with special focus on the utility of echocardiography and CMR for identifying benign and "malignant" forms of MVP...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644230/noble-and-excel-the-debate-for-excellence-in-dealing-with-left-main-stenosis
#7
Hamood Al Kindi, Amir Samaan, Hatem Hosny
Left main coronary artery (LMCA) disease is associated with increased morbidity and mortality. Coronary artery bypass grafting surgery (CABG) has always been the standard revascularization strategy for this group of patients. However, with the recent developments in stents design and medical therapy over the past decade, several trials have been designed to evaluate the safety and efficacy of percutaneous coronary intervention (PCI) as an alternative to CABG surgery in patients with LMCA disease. Recently, the results of two major trials, EXCEL and NOBLE, comparing CABG versus PCI in this patient population have been released...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644229/cantos-a-breakthrough-that-proves-the-inflammatory-hypothesis-of-atherosclerosis
#8
Mohamed Hassan
Atherosclerosis is no longer considered solely a disorder of subintimal deposition of modified low-density lipoprotein particles in the arterial wall. Rather, it is known to be a chronic inflammatory disorder. No evidence has shown that reducing vascular inflammation in the absence of concomitant lowering of lipoproteins levels reduces the rates of adverse cardiovascular (CV) events. Canakinumab, a fully human monoclonal antibody that neutralizes interleukin (IL)-1β, significantly reduced the rate of recurrent CV events in patients with prior myocardial infarction in the Canakinumab Anti-inflammatory Thrombosis Outcome Study (CANTOS)...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29644228/how-are-countries-dealing-with-their-current-cardio-vascular-disease-burden-a-snapshot-from-the-who-eastern-mediterranean-region-emr
#9
EDITORIAL
Asmus Hammerich
In recent years, a number of global commitments have been made in the area of noncommunicable diseases (NCD). These include the UN NCD Political Declaration in 2011, and the UN Comprehensive Review on NCDs and Outcome Document in 2014. Nine global targets have been agreed in the area of NCDs, and NCDs have been addressed in the Sustainable Development Goals (SDG). Another UN high-level meeting will take place in September 2018 to assess country progress across the globe. At the regional level, a number of initiates have taken place to deliver on these global commitments...
March 14, 2018: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564353/pseudo-normalization-of-a-coronary-artery-aneurysm-detected-by-ivus
#10
Sherif Rizk, Waseem Amin, Hala Hamza, Karim Said, Galal El Said
No abstract text is available yet for this article.
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564352/management-of-sequelae-of-kawasaki-disease-in-adults
#11
REVIEW
John B Gordon, Jane C Burns
Background: A growing population of young adults is presenting to cardiologists with late manifestations of Kawasaki disease (KD) that include cardiomyopathy, ischemia, and infarction. The management of these conditions differs in important ways from atherosclerotic heart disease, and yet there is little awareness in the adult cardiology community regarding the special challenges posed by the cardiovascular sequelae of KD. Methods: Observations were made on a population of 140 adult KD patients enrolled in the San Diego Adult KD Collaborative Study...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564351/frequently-asked-questions-regarding-treatment-of-kawasaki-disease
#12
REVIEW
Jane C Burns
No abstract text is available yet for this article.
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564350/computational-blood-flow-simulations-in-kawasaki-disease-patients-insight-into-coronary-artery-aneurysm-hemodynamics
#13
Noelia Grande Gutierrez, Andrew Kahn, Jane C Burns, Alison L Marsden
No abstract text is available yet for this article.
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564349/computed-tomography-coronary-angiography-is-the-way-forward-for-evaluation-of-children-with-kawasaki-disease
#14
REVIEW
Manphool Singhal, Pankaj Gupta, Surjit Singh, Niranjan Khandelwal
Kawasaki disease (KD) is an acute idiopathic vasculitis affecting infants and children. Coronary artery abnormalities and myocarditis are the major cardiovascular complications of KD. Coronary artery abnormalities develop in 15-25% of untreated KD. Two-dimensional transthoracic echocardiography has hitherto been considered the modality of choice for evaluation of children with KD. There are, however, several limitations inherent to echocardiography - including limited evaluation of distal vessels, left circumflex artery and poor acoustic window in growing children...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564348/acute-kawasaki-disease-with-emphasis-on-the-echocardiographic-profile-a-single-center-experience
#15
Hala S Hamza, Wessam A Raouf, Asmaa Z Zaher, Hala M Agha
Background: Echocardiographic features of acute Kawasaki disease (KD) have not been well characterized in Egyptian children. This study aimed to provide insight into the pattern of cardiac involvement in Egyptian children with Kawasaki disease, focusing on echocardiographic coronary abnormalities and their associated risk predictors. Methods and Results: Medical records of 64 KD patients from 2012 to 2016 were retrospectively analyzed with recalculation of coronary artery z-scores during the first eight weeks after fever onset...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564347/aneurysmal-coronary-artery-disease-an-overview
#16
REVIEW
Mohamed S ElGuindy, Ahmed M ElGuindy
Aneurysmal coronary artery disease (ACAD) comprises both coronary artery aneurysms (CAA) and coronary artery ectasia (CAE). The reported prevalence of ACAD varies widely from 0.2 to 10%, with male predominance and a predilection for the right coronary artery (RCA). Atherosclerosis is the commonest cause of ACAD in adults, while Kawasaki disease is the commonest cause in children and adolescents, as well as in the Far East. Most patients are asymptomatic, but when symptoms do exist, they are usually related to myocardial ischemia...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564346/kawasaki-disease-among-egyptian-children-a-case-series
#17
Tarek Hamed Attia, Saed M Morsy, Bashier A Hassan, Al Shymaa A Ali
Kawasaki disease is an acute vasculitis of early childhood. Its incidence varies among different ethnic groups with higher rates among Asians. In this case series, we presented four cases of Kawasaki disease with incomplete or atypical presentations in Egyptian children. Two cases presented with meningitis, which is not a criteria for the diagnosis of Kawasaki disease. The other two cases presented with pharyngitis and fever, which did not respond to antibiotics. The clinical criteria for diagnosis of Kawasaki disease were either incomplete or appeared sequentially...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564345/incomplete-kawasaki-disease-in-egypt
#18
Hala M Agha, Hala S Hamza
No abstract text is available yet for this article.
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564344/cardiovascular-outcomes-following-kawasaki-disease-in-moscow-russia-a-single-center-experience
#19
Galina Lyskina, Olga Bockeria, Olga Shirinsky, Alena Torbyak, Anna Leontieva, Nina Gagarina, Anna Satyukova, Julia Kostina, Olga Vinogradova
Background: Awareness of Kawasaki disease (KD) is emerging in Russia but the diagnosis is still often missed. Methods: This is a retrospective study of 303 children with KD who received care at a single center in Moscow over the period from 2004 to 2016. Results: Overall, coronary artery aneurysms were documented in 91 (30,0%) of 303 patients and transient ectasia in 40 (13,2%). Intracoronary thrombi were found in 12 of 15 patients with giant aneurysms and in 3 patients with medium-sized aneurysms. Conclusion: The patients with KD in the Moscow region had typical features of the disease described in the literature but the proportion of patients with coronary artery aneurysms was higher than reported from other countries...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564343/remote-sensing-observation-of-annual-dust-cycles-and-possible-causality-of-kawasaki-disease-outbreaks-in-japan
#20
Hesham El-Askary, Nick LaHaye, Erik Linstead, William A Sprigg, Magdi Yacoub
Kawasaki disease (KD) is a rare vascular disease that, if left untreated, can result in irreparable cardiac damage in children. While the symptoms of KD are well-known, as are best practices for treatment, the etiology of the disease and the factors contributing to KD outbreaks remain puzzling to both medical practitioners and scientists alike. Recently, a fungus known as Candida, originating in the farmlands of China, has been blamed for outbreaks in China and Japan, with the hypothesis that it can be transported over long ranges via different wind mechanisms...
October 31, 2017: Global Cardiology Science & Practice
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