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United European Gastroenterology Journal

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https://www.readbyqxmd.com/read/29774164/young-gi-angle-how-to-write-a-good-conference-abstract
#1
Julia Krajewska, Louis Vermeulen
No abstract text is available yet for this article.
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774163/in-response-to-fluid-resuscitation-with-lactated-ringer-s-solution-vs-normal-saline-in-acute-pancreatitis-a-triple-blind-randomized-controlled-trial
#2
Bernardo Calamo-Guzman, Luis De Vinatea-Serrano, Alejandro Piscoya
No abstract text is available yet for this article.
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774162/a-large-proportion-of-fecal-immunochemical-test-positive-participants-in-colorectal-cancer-screening-is-symptomatic
#3
Clasine M de Klerk, Manon van der Vlugt, Patrick M Bossuyt, Evelien Dekker
Background: Symptomatic invitees are advised not to participate in colorectal cancer (CRC) screening but to directly consult their general practitioner (GP), because fecal immunochemical test (FIT) sensitivity for cancer is not optimal. This recommendation may not always be followed in daily practice. We evaluated how many FIT-positive participants had CRC-related symptoms and whether the presence of symptoms was associated with the presence and location of CRC/advanced neoplasia. Methods: We prospectively collected data on CRC-related symptoms in all FIT-positive participants in the Dutch CRC screening program, referred to our endoscopy centers between 2014 and 2016, and evaluated whether symptoms were associated with detected CRC/advanced neoplasia at colonoscopy...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774161/endoscopic-full-thickness-resection-eftr-of-colorectal-neoplasms-with-the-full-thickness-resection-device-ftrd-clinical-experience-from-two-tertiary-referral-centers-in-switzerland
#4
Patrick Aepli, Dominique Criblez, Stephan Baumeler, Jan Borovicka, Remus Frei
Background: Endoscopic full thickness resection (EFTR) by the Full Thickness Resection Device (FTRD) has recently been introduced as a method to allow resection of certain lesions such as adenomatous polyps that would not be resectable by standard polypectomy techniques. We report our clinical experience with FTRD procedures, assessing technical success, completeness of resection (R0 status), rate of histologically proven FTR and safety. Patients and methods: We conducted a retrospective analysis of 33 consecutive patients with colonic polyps treated with FTRD from May 2015 to November 2016...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774160/underwater-endoscopic-colorectal-polyp-resection-feasibility-in-everyday-clinical-practice
#5
Sergio Cadoni, Mauro Liggi, Paolo Gallittu, Donatella Mura, Lorenzo Fuccio, Malcolm Koo, Sauid Ishaq
Background: Endoscopic mucosal resection is well-established for resecting flat or sessile benign colon polyps. The novel underwater endoscopic mucosal resection eschews submucosal injection prior to endoscopic mucosal resection. Reports about underwater endoscopic mucosal resection were limited to small series of single and/or tertiary-care referral centers, with single or supervised operators. Objective: The purpose of this study was to determine feasibility and efficacy of underwater resection of polyps of any morphology (underwater polypectomy, here includes underwater endoscopic mucosal resection) in routine clinical practice...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774159/toll-like-receptors-2-and-4-modulate-intestinal-il-10-differently-in-ileum-and-colon
#6
Eva Latorre, Elena Layunta, Laura Grasa, Julián Pardo, Santiago García, Ana I Alcalde, José E Mesonero
Background: Inflammatory bowel diseases are consequence of an intestinal homeostasis breakdown in which innate immune dysregulation is implicated. Toll-like receptor (TLR)2 and TLR4 are immune recognition receptors expressed in the intestinal epithelium, the first physical-physiological barrier for microorganisms, to inform the host of the presence of Gram-positive and Gram-negative organisms. Interleukin (IL)-10 is an essential anti-inflammatory cytokine that contributes to maintenance of intestinal homeostasis...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774158/efficacy-of-vedolizumab-for-induction-of-clinical-response-and-remission-in-patients-with-moderate-to-severe-inflammatory-bowel-disease-who-failed-at-least-two-tnf-antagonists
#7
Martine De Vos, Barbara Dhooghe, Severine Vermeire, Edouard Louis, Fazia Mana, Ann Elewaut, Peter Bossuyt, Filip Baert, Catherine Reenaers, Marc Van Gossum, Elisabeth Macken, Marc Ferrante, Pieter Hindryckx, Olivier Dewit, Tom Holvoet, Denis Franchimont
Background: Vedolizumab is a recently available monoclonal antibody targeting α4β7 integrin for the treatment of ulcerative colitis (UC) and Crohn's disease (CD). Objective: The objective of this article is to evaluate the efficacy of vedolizumab induction therapy in anti-TNF-refractory/intolerant UC and CD patients in real life. Methods: A cohort of 149 moderately to severely active UC and CD patients who failed or showed intolerance to at least two TNF antagonists participated in a medical need program and received vedolizumab in 37 Belgian centers (April-September 2015)...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774157/risk-assessment-of-choledocholithiasis-prior-to-laparoscopic-cholecystectomy-and-its-management-options
#8
Ausra Aleknaite, Gintaras Simutis, Juozas Stanaitis, Jonas Valantinas, Kestutis Strupas
Background: Accurate risk evaluation of choledocholithiasis prior to laparoscopic cholecystectomy is essential to determine optimal management strategy. Objective: Our study aimed to evaluate the accuracy of separate predictors and Vilnius University Hospital Index (VUHI = A/30 + 0.4 × B; A = total bilirubin concentration (µmol/l), B = common bile duct (CBD) diameter (mm) measured by ultrasound) diagnosing choledocholithiasis and to assess different management strategies (cholecystectomy with intraoperative cholangiography and endoscopic retrograde cholangiopancreatography (ERCP))...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774156/pilot-study-of-orphenadrine-as-a-novel-treatment-for-muscle-cramps-in-patients-with-liver-cirrhosis
#9
Sherief Abd-Elsalam, Ferial El-Kalla, Lobna A Ali, Samah Mosaad, Walaa Alkhalawany, Berihan Elemary, Rehab Badawi, Asmaa Elzeftawy, Amr Hanafy, Asem Elfert
Background and aims: Muscle cramps markedly affect the quality of life in cirrhotic patients with no available highly effective treatment. The aim of this study was to assess the safety and efficacy of orphenadrine in the treatment of muscle cramps in cirrhotic patients. Methods: The study enrolled 30 liver cirrhosis patients complaining of frequent muscle cramps (≥3 per week), who were randomized to receive either orphenadrine 100 mg or calcium carbonate 500 mg twice daily as a control for one month...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774155/is-de-novo-hepatocellular-carcinoma-after-transjugular-intrahepatic-portosystemic-shunt-increased
#10
A Hüsing-Kabar, T Meister, M Köhler, W Domschke, I Kabar, C Wilms, B Hild, H H Schmidt, H S Heinzow
Background: Portal hypertension is a major complication of liver cirrhosis. Transjugular intrahepatic portosystemic shunt is effective in treatment of portal hypertension. However, decreased parenchymal portal venous flow after transjugular intrahepatic portosystemic shunt insertion favours ischaemic liver injury which has been discussed to induce hepatocarcinogenesis causing hepatocellular cancer. Aim: This study aimed to explore the association between transjugular intrahepatic portosystemic shunt placement and the development of hepatocellular cancer...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774154/benzodiazepines-and-risk-for-hepatic-encephalopathy-in-patients-with-cirrhosis-and-ascites
#11
Lisbet Grønbæk, Hugh Watson, Hendrik Vilstrup, Peter Jepsen
Background: There is limited evidence to support the belief that benzodiazepines increase cirrhosis patients' risk of hepatic encephalopathy (HE). Objective: We aimed to examine the association between benzodiazepine use and HE development in cirrhosis patients. Methods: We used data on 865 cirrhosis patients with ascites from three trials to study the effect of benzodiazepine use on development of first-time HE. For each patient, we classified periods of benzodiazepine use by the number of days since initiation...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774153/burden-of-impaired-sleep-quality-on-work-productivity-in-functional-dyspepsia
#12
Juntaro Matsuzaki, Hidekazu Suzuki, Koji Togawa, Tsuyoshi Yamane, Hideki Mori, Takahiro Komori, Tatsuhiro Masaoka, Takanori Kanai
Background: Impaired sleep quality is common, and can reduce work productivity in patients with functional dyspepsia (FD). Objective: The objective of this article is to evaluate whether there is a direct association between the presence of FD and the severity of impaired sleep quality, and to calculate the economic loss due to the decreased work productivity associated with sleep quality. Methods: In Study 1, using a web-based survey completed by workers with and without FD, we evaluated impaired sleep quality, work and daily productivity, and the severity of reflux and bowel symptoms...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774152/acquisition-of-double-mutation-in-gyra-caused-high-resistance-to-sitafloxacin-in-helicobacter-pylori-after-unsuccessful-eradication-with-sitafloxacin-containing-regimens
#13
Hideki Mori, Hidekazu Suzuki, Juntaro Matsuzaki, Tatsuhiro Masaoka, Takanori Kanai
Background and aim: Although sitafloxacin (STFX)-containing regimens are effective rescue treatments for Helicobacter pylori infection, prevalence of fluoroquinolone resistance in H. pylori has increased rapidly worldwide. The change in resistance levels and gyrA mutations, a major cause of fluoroquinolone resistance, after unsuccessful STFX-containing treatment has not been investigated. Methods: We conducted a retrospective, non-randomized study to compare the minimum inhibitory concentrations (MICs) of STFX and the location of gyrA mutations in H...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774151/gastrointestinal-endoscopy-under-sedation-is-associated-with-pneumonia-in-older-inpatients-results-of-a-retrospective-case-control-study
#14
Christopher M Kollmann, Wolff Schmiegel, Thorsten Brechmann
Background and aims: Apparent aspiration is a notable adverse event during gastrointestinal endoscopy under sedation (GIES), but data about inapparent aspiration are scarce. Generally, particularly older patients are at higher risk of suffering from adverse events. Objective: The objective of this article is to determine the risk of pneumonia, lower respiratory tract infection (LRI) and systemic inflammatory activation after GIES, especially in patients of at least 65 years...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774150/the-effect-of-off-hours-hospital-admission-on-mortality-and-clinical-outcomes-for-patients-with-upper-gastrointestinal-hemorrhage-a-systematic-review-and-meta-analysis-of-20-cohorts
#15
Xian Feng Xia, Philip Wai Yan Chiu, Kelvin Kam Fai Tsoi, Francis Ka Leung Chan, Joseph Jao Yiu Sung, James Yun Wong Lau
Objective: The objective of this article is to evaluate the relationship between off-hours hospital admission (weekends, public holidays or nighttime) and mortality for upper gastrointestinal hemorrhage (UGIH). Methods: Medline, Embase, Scopus, and the Chinese Biomedical Literature were searched through December 2016 to identify eligible records for inclusion in this meta-analysis. A random-effects model was applied. Results: Twenty cohort studies were included for analysis...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774149/the-rome-iv-versus-rome-iii-criteria-for-heartburn-diagnosis-a-comparative-study
#16
Mengyu Zhang, Minhu Chen, Sui Peng, Yinglian Xiao
Background: The phenotypes of heartburn patients are heterogeneous. Objective: The objective of this study was to investigate the proportion of heartburn phenotypes in a Chinese population and to compare the Rome IV and III criteria for heartburn diagnosis. Methods: A retrospective study was performed among heartburn patients referred for upper endoscopy and esophageal function tests in a tertiary hospital. Their symptoms fulfilled Rome IV and III criteria...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774148/genetic-variations-in-the-tlr3-locus-are-associated-with-eosinophilic-esophagitis
#17
Robledo Ávila-Castellano, José-Raúl García-Lozano, Stefan Cimbollek, Alfredo J Lucendo, Juan-Manuel Bozada, Joaquín Quiralte
Background: Eosinophilic esophagitis (EoE) is an antigen-driven disease mediated by an abnormal immune Th2 response. Objective: The objective of this article is to investigate genes associated with regulating immune responses leading to disease susceptibility. Methods: Twenty-seven tag single nucleotide polymorphisms (tSNPs) selected in five candidate genes ( TLR3, TLR4, FOXP3, FLG and TSLP ) were genotyped in 218 EoE patients and 376 controls...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774147/social-group-disparities-in-the-incidence-and-prognosis-of-oesophageal-cancer
#18
REVIEW
Shao-Hua Xie, Jesper Lagergren
There are substantial disparities in the incidence and prognosis of oesophageal cancer across social population groups, including sex, race/ethnicity, geographical location and socio-economic status. Both squamous cell carcinoma and adenocarcinoma of the oesophagus are more common in men than in women, but the male predominance in adenocarcinoma is stronger and less well understood. The varying incidence and prognosis of oesophageal cancer across racial/ethnic groups show distinct patterns by histological type...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29774146/endoscopic-and-angiographic-management-of-lower-gastrointestinal-bleeding-review-of-the-published-literature
#19
REVIEW
David J Werner, Hendrik Manner, Marc Nguyen-Tat, Roman Kloeckner, Ralf Kiesslich, Nael Abusalim, Johannes W Rey
Lower gastrointestinal bleeding is common and occurs often in elderly patients. In rare cases it is associated with hemorrhagic shock. A large number of such bleedings, which are often caused by colon diverticula, subside spontaneously. Alternatively they can be treated by endoscopic procedures successfully. Given the aging population of our society, the rising incidence of lower gastrointestinal tract bleeding and new anticoagulant therapies, some of the bleedings tend to be severe. Colonoscopy is the established standard procedure for the diagnosis and treatment of lower gastrointestinal bleeding...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29511563/young-gi-angle-boosting-your-career-development-with-fellowship-experience
#20
Paula Mosinska, Raquel Abalo
No abstract text is available yet for this article.
March 2018: United European Gastroenterology Journal
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