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Journal of Traditional and Complementary Medicine

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https://www.readbyqxmd.com/read/29034205/kaempferia-parviflora-rhizome-extract-and-myristica-fragrans-volatile-oil-increase-the-levels-of-monoamine-neurotransmitters-and-impact-the-proteomic-profiles-in-the-rat-hippocampus-mechanistic-insights-into-their-neuroprotective-effects
#1
Waluga Plaingam, Siriporn Sangsuthum, Wannee Angkhasirisap, Tewin Tencomnao
Potentially useful in the treatment of neurodegenerative disorders, Kaempferia parviflora and Myristica fragrans have been shown to possess a wide spectrum of neuropharmacological activities and neuroprotective effects in vivo and in vitro. In this study, we determined whether and how K. parviflora ethanolic extract and M. fragrans volatile oil could influence the levels of neurotransmitters and the whole proteomic profile in the hippocampus of Sprague Dawley (SD) rats. The effects of K. parviflora and M...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034204/studies-on-analgesic-anti-inflammatory-activities-of-stem-and-roots-of-inula-cuspidata-c-b-clarke
#2
Sarvesh Kumar Paliwal, Bhawana Sati, Samriti Faujdar, Swapnil Sharma
The present study was carried out to evaluate analgesic and anti-inflammatory activities in Inula cuspidata stem and root extracts along with heavy metals estimation in stem and root powder. Stem and roots were extracted with chloroform (ICSCE, ICRCE) and methanol (ICSME, ICRME). Acute oral toxicity of all extracts was determined by OECD guidelines 425. Analgesic activity was investigated by using hot plate and acetic acid induced writhing models. Anti-inflammatory activity (acute) of all extracts was evaluated by carrageenan induced paw edema model...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034203/immediate-effect-of-bitter-gourd-ash-gourd-knol-khol-juices-on-blood-sugar-levels-of-patients-with-type-2-diabetes-mellitus-a-pilot-study
#3
G Selvakumar, G Shathirapathiy, R Jainraj, P Yuvaraj Paul
AIM: The aim of this study was to investigate the immediate effect of bitter gourd, Knol-khol, and ash gourd juices on blood glucose level among Type II diabetes mellitus patients. METHODS: In 2015, pilot study was conducted randomly enrolling 30 patients with type 2 diabetes mellitus into three groups in SRK college, India. The first group received bitter gourd juice at FBS range between 120 to 300 mg per dl. The second, third group received Knol-khol, ash gourd juice respectively in the same range of fasting blood sugar level...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034202/wound-healing-potentials-of-thevetia-peruviana-antioxidants-and-inflammatory-markers-criteria
#4
Nazneen Rahman, Haseebur Rahman, Mir Haris, Riaz Mahmood
Thevetia peruviana is a medicinal plant used in the treatment of external wounds, infected area, ring worms, tumours etc. in traditional system of medicine. The aim of the study was to evaluate the wound healing potentials of T. peruviana leaves hexane (LH) and fruit rind (FW) water extracts and to prove the folkloric claims. The antimicrobial, antioxidant and anti-inflammatory potentials could be important strategies in defining potent wound healing drug. Based on these approaches the current study was designed using incision, excision and dead space wound models with the biochemical, antioxidant enzymes and inflammatory marker analysis...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034201/evaluation-of-zanthoxylum-armatum-roxb-for-in%C3%A2-vitro-biological-activities
#5
Fiaz Alam, Qazi Najam Us Saqib
Zanthoxylum armatum fruits are used traditionally as a spice in various food preparations. The aim of this study was analysis of antimicrobial, cytotoxic, phytotoxic, insecticidal, and anti-leishmanial activity. The crude extract showed 86 ± 10% antifungal activity (Agar tube dilution method) against Trichophyton longifusis while n-hexane, chloroform, and aqueous-methanol fractions inhibited this pathogen by 90 ± 7, 85 ± 10 and 70 ± 9% respectively. The n-hexane and aqueous-methanol fraction also, respectively, showed 40 ± 10 and 87 ± 9% inhibition of Microsporum canis...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034200/promising-effect-of-rosa-damascena-extract-on-high-fat-diet-induced-nonalcoholic-fatty-liver
#6
Ida Davoodi, Roja Rahimi, Mohammad Abdollahi, Fatemeh Farzaei, Mohammad Hosein Farzaei, Zahra Memariani, Fariba Najafi
NAFLD is a chronic liver disease that affects a high proportion of the world's population which causes metabolic and hepatic damages. Rosa damascena Mill is traditionally used as a dietary supplement for liver disorders. This study was carried out to determine the beneficial effect of standardized extract of R. damascena on animal model of nonalcoholic fatty liver disease (NAFLD). NAFLD was induced by high-fat diet (HFD) in Wistar rats. HFD rats showed an increase (p < 0.05) in the plasma lipid levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), and reduced the high-density lipoprotein (HDL) levels...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034199/cardioprotective-effects-of-achillea-wilhelmsii-on-the-isolated-rat-heart-in-ischemia-reperfusion
#7
M Mahmoudabady, M Lashkari, S Niazmand, M Soukhtanloo
CONTEXT: There are some reports about protective effects of Achillea on the heart. OBJECTIVE: We investigated the effect of Achillea wilhelmsii extract on cardiac function during ischemia-reperfusion (I/R) injury in the isolated rat heart. MATERIALS AND METHODS: 60 male Wistar rats were randomly divided into 6 groups; 1: Control group, 2: Control-ischemia (CI) 3: vitamin C (10 mg/kg), 4-6: Extract groups (E 100, E 200 and E 400 mg/kg). The animals received normal saline, vitamin C or A...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034198/phenolic-constituents-and-modulatory-effects-of-raffia-palm-leaf-raphia-hookeri-extract-on-carbohydrate-hydrolyzing-enzymes-linked-to-type-2-diabetes
#8
Felix A Dada, Sunday I Oyeleye, Opeyemi B Ogunsuyi, Tosin A Olasehinde, Stephen A Adefegha, Ganiyu Oboh, Aline A Boligon
This study sought to investigate the effects of Raffia palm (Raphia hookeri) leaf extract on enzymes linked to type-2 diabetes mellitus (T2DM) and pro-oxidant induced oxidative stress in rat pancreas. The extract was prepared and its α-amylase and α-glucosidase inhibitory effects were determined. Radical [2,2-diphenyl-1-picrylhydrazyl (DPPH)] scavenging and Fe(2+)-chelating abilities, and inhibition of Fe(2+)-induced lipid peroxidation in rat pancreas homogenate were assessed. Furthermore, total phenol and flavonoid contents, reducing property, and high performance liquid chromatography diode array detector (HPLC-DAD) fingerprint of the extract were also determined...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034197/characterization-of-calcined-jade-and-its-immunomodulatory-effect-on-macrophage-isolated-from-swiss-albino-mice
#9
Asif Elahi, Deeba S Jairajpuri, Farah Khan
Calcined Jade (CJ) is a metasilicate frequently used in traditional system of medicine as tonic to vital organs with several other pharmacological activities. X-ray powder diffraction (XRPD), inductively coupled plasma mass spectrometry (ICP-MS), atomic absorption spectroscopy (AAS) and CHNS analyzer techniques were used to characterize CJ sample. CJ was administered orally to Swiss albino mice at a dose of 50, 75, 100 and 200 μg/kg body weight for 10 days and modulation of the macrophage mediated innate immune responses was studied...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034196/protective-effect-of-ethyl-acetate-fraction-of-biophytum-sensitivum-extract-against-sodium-oxalate-induced-urolithiasis-in-rats
#10
Anil T Pawar, Niraj S Vyawahare
The methanolic whole plant extract of Biophytum sensitivum (gǎnyìng cǎo) has been found to possess antiurolithiatic effect. The present study was undertaken to evaluate the antiurolithiatic effect of some fractions of methanolic whole plant extract of B. sensitivum (MBS) in rats as a step toward activity-directed isolation of antiurolithiatic component. The MBS was successively extracted with dichloromethane, ethyl acetate, ethanol and water to obtain fractions. Sodium oxalate (70 mg/kg, i.p.) was administered to rats for seven days to develop calcium oxalate urolithiasis...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034195/protective-effect-of-hydro-alcoholic-extract-of-salvia-haematodes-wall-root-on-cognitive-functions-in-scopolamine-induced-amnesia-in-rats
#11
Mohammad Shawwal, Badruddeen, Mohammad Khushtar, Md Azizur Rahman
Diminished cholinergic transmission may be responsible for development of amnesia. Hence, the present study was undertaken to investigate the possible protective effect of hydro-alcoholic extract of Salvia haematodes Wall root (HESH) on cognitive functions in scopolamine-induced amnesia in adult Sprague Dawley rats. The rats were divided randomly into five groups each consisting of five rats (n = 5). Rats of the groups I, II, III, IV, and V received orally normal saline (10 ml/kg b. wt.), normal saline (10 ml/kg), standard drug rivastigmine (1...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034194/evidence-based-study-of-antidiabetic-potential-of-c-maxima-seeds%C3%A2-%C3%A2-in%C3%A2-vivo
#12
Devesh Kumar Kushawaha, Manjulika Yadav, Sanjukta Chatterji, Amrita Kumari Srivastava, Geeta Watal
OBJECTIVE: In vitro antidiabetic efficacy of Cucurbita maxima seed extract (CMSE) has already been studied in our previous findings. Thus, in order to validate these findings in biological system, in vivo antidiabetic activity of aqueous extract was investigated in normal as well as diabetic experimental models. METHODS: Variable doses of extract were administered orally to normal and STZ induced mild diabetic rats during fasting blood glucose (FBG) and glucose tolerance test (GTT) studies...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034193/comparative-study-of-herbal-plants-on-the-phenolic-and-flavonoid-content-antioxidant-activities-and-toxicity-on-cells-and-zebrafish-embryo
#13
Hassan Fahmi Ismail, Zanariah Hashim, Wong Tet Soon, Nur Syukriah Ab Rahman, Ain Nabihah Zainudin, Fadzilah Adibah Abdul Majid
Natural antioxidants derived from plants have shown a tremendous inhibitory effect on free radicals in actively metabolizing cells. Overproduction of free radicals increases the risk factor of chronic diseases associated with diabetes, cancer, arthritis and cardiovascular disease. Andrographis paniculata, Cinnamon zeylanicum, Curcuma xanthorrhiza, Eugenia polyantha and Orthosiphon stamineus are ethnomedicinal plants used in the Asian region to treat various illnesses from a common fever to metabolic disease...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034192/evaluation-of-analgesic-and-anti-inflammatory-activity-of-bridelia-retusa-spreng-bark
#14
Anil U Tatiya, Ajay K Saluja, Mohan G Kalaskar, Sanjay J Surana, Prakash H Patil
Several species of Bridelia have been used in the condition of pain & arthritis in Indian folk medicine. Present study revealed the preliminary phytochemical investigation and evaluation of analgesic, anti-inflammatory and anti-arthritic activity as well as underlying mechanism of bark of Bridelia retusa Spreng. (Euphorbiaceae). The bark was subjected to extraction using pet.ether, ethyl acetate and acetone. All the extracts were significantly inhibit abdominal writhings response and licking time in late phase of formalin test...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034191/pharmacological-properties-of-salvia-officinalis-and-its-components
#15
Ahmad Ghorbani, Mahdi Esmaeilizadeh
Salvia officinalis (Sage) is a plant in the family of Labiatae/Lamiaceae. It is native to Middle East and Mediterranean areas, but today has been naturalized throughout the world. In folk medicine, S. officinalis has been used for the treatment of different kinds of disorders including seizure, ulcers, gout, rheumatism, inflammation, dizziness, tremor, paralysis, diarrhea, and hyperglycemia. In recent years, this plant has been a subject of intensive studies to document its traditional use and to find new biological effects...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034190/antiasthmatic-related-properties-of-abrus-precatorius-leaves-on-various-models
#16
Dnyaneshwar J Taur, Rajendra N Patil, Ravindra Y Patil
OBJECTIVE: Asthma is a multifaceted inflammatory disorder which results into narrowing of airway with broncho-constriction and spasm. As the complex pathophysilogy of asthma, various animal models are generally used to investigate the immunological and physiological pathogenesis of disease. Abrus precatorius Linn (Fabacease) is a climbing shrub. The leaves and roots are sweet in taste and traditionally used for the treatment of asthma, bronchititis, and inflammation. A. precatorius possesses different pharmacological activities...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034189/antidiabetic-activity-of-extracts-of-anacardium-occidentale-linn-leaves-on-n-streptozotocin-diabetic-rats
#17
Y S Jaiswal, P A Tatke, S Y Gabhe, A B Vaidya
Anacardium occidentale L. (Anacardiaceae) is used in South Cameroon as well as in other tropical countries by traditional practitioners as a folk remedy for treatment of diabetes mellitus. We demonstrated the antidiabetic potential of the plant extracts in n-streptozotocin diabetic rats. The aim of the current study was to investigate the antidiabetic effects of ethanol extract of leaves of A. occidentale on neonatal streptozotocin diabetic rats. Two day old neonates were injected with 100 mg/kg of streptozotocin...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034188/validation-of-therapeutic-anti-inflammatory-potential-of-arjuna-ksheera-paka-a-traditional-ayurvedic-formulation-of-terminalia-arjuna
#18
Nivedita Dube, Chetan Nimgulkar, Dinesh Kumar Bharatraj
Arjuna Ksheera Paka (AKP), a traditional Ayurvedic formulation of Terminalia arjuna (T. arjuna) bark powder is used for its cardioprotective effects. However, its anti-inflammatory efficacy remained unexplored. In the present study, AKP was prepared in cow milk (as per standard Ayurvedic procedure) and compared with standard hydroalcoholic extract (HA) of T. arjuna. The extracts were analyzed for gross phytoconstituents levels, and their antioxidant activity was assayed by DPPH free radical scavenging activity and inhibition of lipid peroxidation...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034187/electrical-nerve-stimulation-for-xerostomia-a-meta-analysis-of-randomised-controlled-trials
#19
REVIEW
Gowri Sivaramakrishnan, Kannan Sridharan
BACKGROUND: Xerostomia leads to caries, infection and overall psychological discomfort. Salivary substitutes and pharmacological agents have been tried only with temporary relief. The use of transcutaneous electrical nerve stimulation (TENS) has been contemplated on by various researchers for treatment of xerostomia. We carried out the present review as a systematic compilation and quantitative synthesis of the existing evidence related to the utility of TENS in patients with xerostomia...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29034186/medicinal-biological-and-phytochemical-properties-of-gentiana-species
#20
REVIEW
Fatemeh Mirzaee, Amirsaeed Hosseini, Hossein Bakhshi Jouybari, Ali Davoodi, Mohammad Azadbakht
Gentiana, a cosmopolitan and important genus of the Gentianaceae family, comprises 400 species distributed among the world. Based on the studies of Iranian traditional medicine texts, there are some promising bioactivities for this genus that is unknown in modern medicine and some of them are still the basis of new remedies. In traditional medicine texts, Gentiana's different exclusive forms of preparations are effective for treatment of some disorders such as menstrual over-bleeding, conjunctivitis, vitiligo, animals venom poisoning, injuries, infected wounds, pain and swelling of liver, spleen, stomach and sprains of muscles...
October 2017: Journal of Traditional and Complementary Medicine
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