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Journal of Traditional and Complementary Medicine

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https://www.readbyqxmd.com/read/27774432/inhibitory-effect-of-curcumin-on-angiogenesis-in-a-streptozotocin-induced-diabetic-rat-model-an-aortic-ring-assay
#1
Mohammad Hossein Dehghan, Hossein Mirmiranpour, Sara Faghihi-Kashani, Kourosh Kabir, Mehrdad Larry, Ehsan Zayerzadeh, Salume Salehi
BACKGROUND: Curcumin (diferuloylmethane) has been associated with the inhibition of angiogenesis, as well as the prevention of cancers and inflammatory processes. The aim of this study was to assess the efficacy of curcumin in suppressing angiogenesis in the cultured endothelial cells of rat aortic rings. METHODS: Eight-week-old male Wistar rats were randomized into five groups each with a different treatment and cell culturing paradigm: controls cultured in the absence of VEGF (vascular endothelial growth factor) (C), controls cultured in the presence of VEGF (C-V), controls treated with curcumin and then cultured in media lacking VEGF (C-TC), diabetics cultured in media supplemented with VEGF (D-V) and diabetics treated with curcumin and then cultured in media supplemented with VEGF (D-V-TC)...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774431/diuretic-and-antiurolithiatic-activities-of-an-ethanolic-extract-of-acorus-calamus-l-rhizome-in-experimental-animal-models
#2
Hardik Ghelani, Maunik Chapala, Pinakin Jadav
Acorus calamus is a plant commonly used as a traditional herbal medicine and possesses the wide range of pharmacological applications. The present study investigated the diuretic and antiurolithiatic activities of an ethanolic extract of Acorus calamus L. (Family: Araceae) rhizome (EEAC). For diuretic activity, three doses of EEAC (250, 500 and 750 mg/kg) were studied, and measurement of the urinary volume and electrolytes (Na(+) and K(+)) concentration were taken as evaluation parameters. On the other hand, ethylene glycol induced urolithiasis (0...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774430/enhancement-of-the-th1-phenotype-immune-system-by-the-intake-of-oyster-mushroom-tamogitake-extract-in-a-double-blind-placebo-controlled-study
#3
Aiko Tanaka, Mie Nishimura, Yuji Sato, Hiroki Sato, Jun Nishihira
Pleurotus cornucopiae (Oyster mushroom, Tamogitake) has long been eaten as a functional food for enhancement of the immune system, but its effectiveness has not been well confirmed in humans. To this end, we set up a double-blind placebo-controlled human clinical trial to investigate the potential of Oyster mushrooms with respect to the up-regulation of the immune system. The subjects ingested Oyster mushroom extract for 8 weeks. We measured the serum cytokine levels involved in regulation of the immune system, including interferon (IFN)-γ, interleukin (IL)-4, IL-5, IL-10, IL-12, IL-13, and tumor-necrosis factor (TNF)-α...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774429/preventive-potentials-of-piperlongumine-and-a-piper-longum-extract-against-stress-responses-and-pain
#4
Vaishali Yadav, Shyam Sunder Chatterjee, Muhammed Majeed, Vikas Kumar
AIM: To compare stress resistance increasing and analgesic activities of piperlongumine and a methanolic Piper longum fruit extract (PLE). METHODS: Efficacies of a single and repeated daily oral doses (1-256 mg/kg/day) of PLE, piperlongumine, and 50 mg/kg/day doxycycline against foot shock stress triggered alteration in body weights and core temperatures, and of their 11 daily doses on antidepressants like activity in tail suspension test and on pentobarbital induced sedation in male mice were compared...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774428/acupuncture-combined-with-chinese-herbs-for-the-treatment-in-hemivertebral-french-bulldogs-with-emergent-paraparesis
#5
Ching Ming Liu, G Reed Holyoak, Chung Tien Lin
This study follows the treatment of six French bulldogs with paraparesis caused by congenital hemivertebra which were structurally mild but clinically severe. A standardized acupuncture ( zhēn jiǔ) treatment using Hua-Tuo-Jiaji (HTJJ) as local points and other distant points combined with Chinese herbs improved the clinical signs. Few, if any, published papers mention Traditional Chinese Veterinary Medicine (TCVM) for treatment of hemivertebral paraparesis in French bulldogs. Based on the rapid treatment outcome, we encourage practitioners to integrate this form of conservative management into emergency treatment...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774427/influence-of-traditional-chinese-medicine-syndrome-groups-on-quality-of-life-in-women-with-metabolic-syndrome
#6
Li-Wen Huang, I-Ju Chen, Chung-Hua Hsu
Traditional Chinese medicine (TCM; zhōng yī) syndrome groups are based on the symptoms of human diseases and guide the use of Chinese herbs. The aim of this study was to examine the effects of TCM syndrome groups on biochemical characteristics and quality of life (QOL) in women with metabolic syndrome (MS). Among the 1080 registered female patients screened at our outpatient clinic, a total of 322 women aged between 18 and 65 years and meeting the requirements of MS were enrolled. All the patients were asked to fill out a questionnaire on metabolic TCM syndrome groups and a questionnaire on the QOL, the Medical Outcomes Study (MOS) Short Form-12 (SF-12)...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774426/antibacterial-and-antibiotic-potentiating-activity-of-vangueria-madagascariensis-leaves-and-ripe-fruit-pericarp-against-human-pathogenic-clinical-bacterial-isolates
#7
M Fawzi Mahomoodally, Schajeed Dilmohamed
This study aimed to assess the antibacterial and antibiotic potentiating property of Vangueria madagascariensis (VM) (fruit and leaf extracts) against 10 clinical isolates. A microdilution broth susceptibility assay for bacteria was used for the determination of the minimum inhibitory concentration (MIC) and associated with antibiotics to evaluate any synergistic effect. VM extracts were found to potentiate the activity of 3 conventional antibiotics. Chloramphenicol and Ciprofloxacin showed no activity against Acinetobacter spp...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774425/a-case-series-of-the-effects-of-a-novel-composition-of-a-traditional-natural-preparation-for-the-treatment-of-psoriasis
#8
A Michalsen, O Eddin, A Salama
The objective of this study was to assess the effectiveness of a specific composition of a traditional herbal preparation (DurrDerma) in adult patients with moderate to severe skin psoriasis. The preparation is a newly developed topical combination containing plant-based extracts traditionally used in skin disease as black cumin, olive oil, tea tree oil, cocoa butter completed by vitamin A and vitamin B12. We documented the effectiveness of the preparation in a first case series. A total of 12 patients (8 males and 4 females, 21-86 y) with manifest and treatment-resistant psoriasis were included and treated for 12 weeks...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774424/anti-arthritic-activity-of-a-classical-ayurvedic-formulation-vatari-guggulu-in-rats
#9
Madhavi G Patel, Kilambi Pundarikakshudu
In India, Vatari Guggulu has been traditionally used in the Ayurvedic system of medicine to treat rheumatoid arthritis (RA). The current study was undertaken to evaluate anti-arthritic activity of alcoholic extract of Vatari Guggulu in rats. Arthritis was induced by administration of formaldehyde (2%v/v) or Complete Freund's Adjuvant (CFA) into the sub-plantar surface of left hind paw of the animals. The extract was administered to the rats by oral gavages in different doses. Joint swelling was measured in formaldehyde induced arthritis...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774423/evaluation-of-in%C3%A2-vivo-antitumor-activity-of-cleistanthin-b-in-swiss-albino-mice
#10
Vipul R Thummar, Subramani Parasuraman, Debdatta Basu, Ramasamy Raveendran
To evaluate the in vivo antitumor activity of cleistanthin B in Ehrlich's ascites carcinoma (EAC) and Dalton's ascites lymphoma (DAL) cell lines induced malignant ascites mouse models and DAL cell line induced solid tumor mouse model. All animals were injected with 2 × 10(6) EAC/DAL cells i.p./s.c. to induce malignant ascites and solid tumor and treated with 5-fluorouracil (5-FU) 20 mg/kg or cleistanthin B for 10 days. Cleistanthin B was given at three doses viz. 25, 50 and 100 mg/kg. The percentage increase in life span and the overall survival in malignant ascites animals and the tumor volume in solid tumor animals were measured...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774422/complementary-and-alternative-medicine-in-indian-parkinson-s-disease-patients
#11
Awadh Kishor Pandit, Deepti Vibha, Achal Kumar Srivastava, Garima Shukla, Vinay Goyal, Madhuri Behari
Use of complementary and alternative medicine (CAM; bǔ chōng yǔ tì dài yī xué) in Parkinson disease (PD) ranged 40-70%. The objective of this study was to determine the frequency, types and factors associated with the use of CAM in Indian PD patients. PD patients, fulfilling UKPD-Society brain-bank diagnostic-criteria, attending Movement-disorders clinic of a tertiary-care teaching hospital in India from 1st May to 15th December 2012 were enrolled. Information on socio-demographic, clinical data and treatment along with factors (source of information, benefits, harms, reason for use and cost) associated with CAM use were recorded...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774421/synergistic-hepatoprotective-potential-of-ethanolic-extract-of-solanum-xanthocarpum-and-juniperus-communis-against-paracetamol-and-azithromycin-induced-liver-injury-in-rats
#12
Hem Singh, Atish Prakash, A N Kalia, Abu Bakar Abdul Majeed
Previously explored combination therapies mostly involved the use of bioactive molecules. It is believed that herbal compounds containing multiple plant products have synergistic hepatoprotective effects and could enhance the desired actions. To investigate the combination of ethanolic fruits extract of Solanum xanthocarpum (SX) and Juniperus communis (JC) against Paracetamol (PCM) and Azithromycin (AZM) induced liver toxicity in rats. Liver toxicity was induced by combine oral administration of PCM (250 mg/kg) and AZM (200 mg/kg) for 7 days in Wistar rats...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774420/centella-asiatica-extract-protects-against-amyloid-%C3%AE-1-40-induced-neurotoxicity-in-neuronal-cells-by-activating-the-antioxidative-defence-system
#13
Chien-Li Chen, Wen-Hao Tsai, Chun-Jen Chen, Tzu-Ming Pan
Centella asiatica ( léi gōng gēn) is a traditional medicinal herb with high antioxidant activity, which decreases amyloid-β (Aβ) deposition in the brain. At the same time, aggregated Aβ-induced oxidative stress is the trigger in the pathogenesis of Alzheimer's disease (AD). Here, we investigated the ability of C. asiatica ethanol extract (CAE) to protect PC12 and IMR32 cells from Aβ1-40-induced production of reactive oxygen species (ROS) and concomitant neurotoxicity. Aggregated Aβ1-40 treatment resulted in reduced cell viability, which can be reversed by cotreatment with 25, 50, and 100 μg/mL CAE...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774419/evaluation-of-anti-inflammatory-activity-of-selected-medicinal-plants-used-in-indian-traditional-medication-system-in%C3%A2-vitro-as-well-as-in%C3%A2-vivo
#14
Rafik U Shaikh, Mahesh M Pund, Rajesh N Gacche
The present study was carried out to evaluate in vivo and in vitro anti-inflammatory potential of selected medicinal plants used in Indian traditional medication. The sequentially extracted plant samples as, Cissus quadrangularis, Plumbago zeylanica, Terminalia bellarica and Terminalia chebula in water, ethanol and hexane were evaluated in-vitro for COX-1 and 2 inhibitory and antioxidant activities. The in vivo anti-inflammatory activity of selected samples showing promising COX-2 inhibition was assessed using carrageenan and Phorbol Myristate Acetate (PMA) induced mice edema animal model...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774418/nephroprotective-effect-of-ethanolic-extract-of-azima-tetracantha-root-in-glycerol-induced-acute-renal-failure-in-wistar-albino-rats
#15
Venugopala Rao Konda, Ruckmani Arunachalam, Madhavi Eerike, Ramesh Rao K, Arun Kumar Radhakrishnan, Lakshmipathy Prabhu Raghuraman, Vinayak Meti, Sobita Devi
The gravity of the impact of renal failure on human health is well known and as there is no specific pharmacotherapy for renal failure, the current study was undertaken to evaluate the effect of root extract of Azima tetracantha, an ancient medicinal plant used in Siddha and Ayurvedhic systems of medicine. The experiment was done in glycerol-induced acute renal failure in Wistar albino rats. Thirty rats were divided into five groups. Group 1 was given normal saline (10 ml/kg) per oral, group 2 with single dose of hypertonic glycerol (8 ml/kg) by intramuscular injection into the hind limbs, group 3 with glycerol and ethanolic extract of A...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774417/green-tea-catechin-inhibits-the-activity-and-neutrophil-release-of%C3%A2-matrix-metalloproteinase-9
#16
Wan K Kim-Park, Eman S Allam, Jadesada Palasuk, Michael Kowolik, Kichuel K Park, L Jack Windsor
Green tea (Camellia sinensis; lǜ chá) extracts have been shown to possess anti-oxidant and anti-inflammatory effects in various cell types. Green tea extract (GTX) has been shown to significantly inhibit the activity of collagenase-3 (matrix metalloproteinase-13 (MMP-13)) in vitro. MMPs, such as MMP-9, are known to be involved in many inflammatory diseases including periodontal disease. GTX and a major catechin, epigallocatechin-gallate (EGCG), were examined for their ability to inhibit purified MMP-9 activity and its release from stimulated neutrophils...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774416/a-randomized-ethnomedicinal-survey-of-snakebite-treatment-in-southwestern-parts-of-bangladesh
#17
Md Nazmul Hasan, Nur Kabidul Azam, Md Nasir Ahmed, Akinori Hirashima
Snakebite is the single most important toxin-related injury, causing substantial mortality in many parts of the Africa, Asia and the Americas. Incidence of snakebite is usually recorded in young people engaged in active physical work in rural areas. The various plant parts used to treat snakebite included whole plant, leaves, barks, roots and seeds. Most bites in Bangladesh are recorded between May and October with highest number in June. Lower and upper limbs are most common sites of snakebite, but it may happen in other sites as well...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774415/cinnamon-extract-lowers-glucose-insulin-and-cholesterol-in-people-with-elevated-serum-glucose
#18
Richard A Anderson, Zhiwei Zhan, Rencai Luo, Xiuhua Guo, Qingqing Guo, Jin Zhou, Jiang Kong, Paul A Davis, Barbara J Stoecker
Cinnamon ( ròu guì) has in vitro insulin potentiating activity, and proanthocyanidins from cinnamon prevent in vitro formation of advanced glycation end products. Some human studies were equivocal, but several have shown beneficial effects of cinnamon supplementation on circulating glucose, lipids, and/or insulin. This placebo-controlled double-blind trial tested the effects of a dried water extract of cinnamon (Cinnamomum cassia) on circulating glucose, lipids, insulin, and insulin resistance. Men and women from Beijing and Dalian, China, were invited to participate if they had fasting serum glucose >6...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774414/antioxidant-effects-of-spirulina-supplement-against-lead-acetate-induced-hepatic-injury-in-rats
#19
Walid Hamdy El-Tantawy
Lead is a toxic metal that induces a wide range of behavioral, biochemical and physiological effects in humans. Oxidative damage has been proposed as a possible mechanism involved in lead toxicity. The current study was carried out to evaluate the antioxidant activities of Spirulina supplement against lead acetate -induced hepatic injury in rats. Five groups of rats were used in this study, Control, Lead acetate (100 mg/kg), Lead acetate (100 mg/kg) + 0.5 g/kg Spirulina, Lead acetate (100 mg/kg) + 1 g/kg Spirulina and Lead acetate + 25 mg/100 g Vitamin C (reference drug)...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27774413/use-of-complementary-and-alternative-medicines-among-malaysian-cancer-patients-a-descriptive-study
#20
Maryam Farooqui, Mohamed Azmi Hassali, Aishah Knight Abdul Shatar, Muhammad Aslam Farooqui, Fahad Saleem, Noman Ul Haq, Che Noriah Othman
The use of Complementary and Alternative Medicine (CAM; bǔ chōng yǔ tì dài yī xué) has been rapidly increasing among cancer patients. However, this pervasiveness is still largely unexplored among Malaysian cancer patients. The current study aimed to evaluate the patterns of CAM use among cancer patients from a local hospital in Malaysia. In addition, the study focused on the information-seeking behavior and CAM use disclosure to doctors. Of 393 patients, 184 (46.1%) had used CAM for their cancers. CAM usage was significantly associated with gender (p = 0...
October 2016: Journal of Traditional and Complementary Medicine
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