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Bianca Lee, Kevin Yeroushalmi, Hay Me Me, Paresh Sojitra, Usman Jilani, Syed Iqbal, Shadab Ahmed, Janice Verley, Jagadish Akella
Introduction: Klebsiella pneumoniae meningitis is most commonly seen as a nosocomial infection and in post-neurosurgical patients. Reports of community acquired Klebsiella pneumoniae meningitis cases are rare in the United States. The objective of this case report is to discuss an uncommon pathogen causing meningitis, Klebsiella pneumoniae , its risk and prognostic factors and to emphasize the importance of early recognition and appropriate antibiotic treatment. Case report: We report a clinical case of adult community acquired Klebsiella pneumoniae meningitis with recovery...
June 2018: Germs
Steev Loyola, Luz Gutierrez, Estrella Avendaño, Nixon Severino, Jesus Tamariz
Introduction: Cell phones are susceptible to bacterial contamination. The aim of this study was to characterize the bacterial isolates and to explore their dispersion in five Intensive Care Units (ICUs) over the time. Methods: We performed a secondary analysis of non-fermenting Gram-negative bacteria and Gram-positive cocci isolated from a 5-month observational cohort study developed among health care workers' cell phones in five ICUs. Cell phones were sampled using a swab every 15 days...
June 2018: Germs
Aziz Bouymajane, Fouzia Rhazi Filali, Said Oulghazi, Abdelaziz Ed-Dra, Faouzia Benhallam, Abdallah El Allaoui, Jawad Anissi, Khalid Sendide, Bouchra Ouhmidou, Mohieddine Moumni
Background: Enterococcus spp. belongs to a group of pathogens which are responsible for serious infections. This study aims at highlighting the raw milk microbiological contamination and at providing data for prevalence and antimicrobial resistance of Enterococcus spp. isolated from raw cow's milk marketed (without any pasteurization) by street traders. Methods: During the period of May 2015 through April 2016, 150 cow's raw milk samples were collected from street traders in Meknes city...
June 2018: Germs
Bazim V Ojeh, Isaac O Abah, Placid Ugoagwu, Patricia A Agaba, Oche O Agbaji, Steven S Gyang
Introduction: The use of tenofovir disoproxil fumarate (TDF) in the treatment of HIV infection has been associated with renal dysfunction. In Nigeria, data on the incidence and risk factors of TDF nephrotoxicity is sparse. We determined the cumulative incidence of and risk factors for TDF-induced renal impairment in HIV-infected individuals accessing care at the antiretroviral therapy (ART) clinic of Jos University Teaching Hospital, Nigeria. Methods: This retrospective cohort analysis included patients aged ≥16 years that initiated ART between January 2008 and December 2011...
June 2018: Germs
Margherita Scapaticci, Andrea Bartolini, Federica Del Chierico, Cristel Accardi, Francesco Di Girolamo, Andrea Masotti, Maurizio Muraca, Lorenza Putignani
Introduction: Yeast pathogens are emerging agents of nosocomial as well as community-acquired infections and their rapid and accurate identification is crucial for a better management of high-risk patients and for an adequate treatment. Methods: We performed a retrospective review of 156 yeast isolates collected during a 17 months' period of regular clinical practice at the Microbiology Department of San Camillo Hospital in Treviso, Italy and analyzed by the traditional culture-based method combined with matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS)...
June 2018: Germs
Padraig M C McGettrick, Elena Alvarez Barco, Greg Kaminskiy, Patrick W G Mallon
No abstract text is available yet for this article.
June 2018: Germs
Heba Y Al Dawodeyah, Nathir Obeidat, Luay F Abu-Qatouseh, Asem A Shehabi
Introduction: Pseudomonas aeruginosa is a common agent causing community acquired and nosocomial respiratory tract infections, with particularly life-threatening manifestations in patients who are immunocompromised of who have cystic fibrosis. This study investigated the occurrence of extended-spectrum β-lactamases (ESBLs) and metallo β-lactamase (MBL) in association with important putative virulence genes and genotypes variation among P. aeruginosa isolates from respiratory tract infection of Jordanian patients...
March 2018: Germs
Zarizal Suhaili, Putri 'Amira Rafee, Norhidayah Mat Azis, Chew Chieng Yeo, Syafinaz Amin Nordin, Abdul Rachman Abdul Rahim, Mazen M Jamil Al-Obaidi, Mohd Nasir Mohd Desa
Introduction: This study aims to assess the antimicrobial susceptibility profiles of Staphylococcus aureus strains isolated from university students and to determine the prevalence of constitutive and inducible clindamycin resistance, the latter being able to cause therapeutic failure due to false in vitro clindamycin susceptibility. Methods: S. aureus strains were isolated from the nasal swabs of 200 health sciences students of a Malaysian university. Twelve classes of antibiotics were used to evaluate the antimicrobial susceptibility profiles with the macrolide-lincosamide-streptogramin B (MLSB ) phenotype for inducible clindamycin resistance determined by the double-diffusion test (D-test)...
March 2018: Germs
Paraskevi Chra, Joseph Papaparaskevas, Eleni Papadogeorgaki, George Panos, Michalis Leontsinidis, George Arsenis, Athanassios Tsakris
Background: The aim of the present study was to determine the prevalence of Mycoplasma genitalium (MG) infection among individuals at high risk for sexually-transmitted diseases (STDs) at a major urban STD clinic in Athens, in view of the lack of data pertaining to this infection in Greece. Methods: Urethral and cervical samples from 176 individuals consecutively attending the clinic and agreeing to participate were prospectively collected and tested for MG infection using conventional PCR and TaqMan Real-Time PCR...
March 2018: Germs
Jean Uwingabiye, Abdelhay Lemnouer, Sabina Baidoo, Mohammed Frikh, Jalal Kasouati, Adil Maleb, Yassine Benlahlou, Fatna Bssaibis, Albert Mbayo, Nawfal Doghmi, Khalil Abouelalaa, Abdelouahed Baite, Azeddine Ibrahimi, Mostafa Elouennass
Introduction: The objective of this study was to examine the epidemiology, risk factors and outcome associated with Acinetobacter baumannii infections in the intensive care units (ICUs) in a Moroccan teaching hospital. Methods: This is a matched case-control study conducted as a joint collaboration between the clinical Bacteriology department and the two ICUs of Mohammed V Military Teaching Hospital from January 2015 to July 2016. Results: Among 964 patients hospitalized in the ICUs, 81 (8...
December 2017: Germs
Siti-Noor-Adnalizawati Adnan, Nazlina Ibrahim, Wan Ahmad Yaacob
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a worldwide public health threat, displaying multiple antibiotic resistance that causes morbidity and mortality. Management of multidrug-resistant (MDR) MRSA infections is extremely difficult due to their inherent resistance to currently used antibiotics. New antibiotics are needed to combat the emergence of antimicrobial resistance. Methods: The in vitro effect of tannins was studied against MRSA reference strain (ATCC 43300) and MRSA clinical strains utilizing antimicrobial assays in conjunction with both scanning and transmission electron microscopy...
December 2017: Germs
George Mondinde Ikomey, Marie Claire Okomo Assoumou, Josiah Otwoma Gichana, Duncan Njenda, Sello Given Mikasi, Martha Mesembe, Emilia Lyonga, Graeme Brendon Jacobs
Introduction: The emergence of drug resistance mutations (DRMs) has been a major threat for successful lifelong combination antiretroviral therapy (cART), especially for HIV-vertically infected children within the context of the prevention of mother-to-child transmission (PMTCT). This study aimed to evaluate DRMs amongst immune competent treatment-naïve children in Cameroon. Methods: A cross-sectional study was conducted between 2015 and 2016 amongst 55 proxy consented HIV-1 positive children, aged 9 months to 6 years...
December 2017: Germs
Zahra Pakbaz, Mohammad Ali Sahraian, Samira Sabzi, Mahmood Mahmoodi, Mohammad Reza Pourmand
Background: Microbial superantigens might initiate or exacerbate autoimmune responses against particular tissues, organs or systems. This study aimed to examine the prevalence of sea, seb, sec, sed, and tsst-1 genes of Staphylococcus aureus in nasal carriage and their association with multiple sclerosis (MS). Methods: Nasal swabs were collected from 150 MS patients and 150 healthy individuals (control group) to isolate S. aureus and investigate their superantigen genes ( sea, seb, sec, sed and tsst-1 ) using PCR...
December 2017: Germs
Richard A Stein
No abstract text is available yet for this article.
December 2017: Germs
Beuy Joob, Viroj Wiwanitkit
No abstract text is available yet for this article.
September 2017: Germs
Eloy E Ordaya, Sulieman Abu Jarir, Robert Yoo, Pranatharthi H Chandrasekar
INTRODUCTION: Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome of hyperinflammation leading to an uncontrolled and ineffective immune response, associated with high mortality. CASE REPORT: A 26-year-old woman with acute lymphoblastic leukemia, 8 months in remission, was found to have HLH. Without any improvement, stem cell transplantation was considered. Then, Mycobacterium avium complex (MAC) infection was identified as cause of her HLH. With appropriate therapy for infection, HLH improved and transplantation was averted...
September 2017: Germs
Nnennaya Anthony Ajayi, Chiedozie Kingsley Ojide, Immanuel Anthony Ajayi, Kingsley Nnanna Ukwaja
INTRODUCTION: Ebola virus disease (EVD) is a highly contagious infection with a high case fatality rate. Thus, there is a crucial need for early detection and reporting of any individual suspected to have EVD in order to facilitate containment strategies. The aim of our study was to evaluate clinicians' reporting proficiency and their risk perceptions of EVD in Ebonyi State, Nigeria. METHODS: We performed a descriptive cross-sectional study conducted among clinicians...
September 2017: Germs
Jayaweera Arachchige Asela Sampath Jayaweera, Wikum Widuranga Kumbukgolla
INTRODUCTION: The animal husbandry comes to play an important role according to new economic reforms of the rural economy in South Asia including Sri Lanka, and the rural farming community has a poor knowledge about hygienic issues of animal husbandry, which can lead to spread of pathogenic bacterial strains from animals to humans. Our study was conducted to evaluate methicillin susceptible Staphylococcus aureus (MRSA) colonization and its antimicrobial resistance pattern among livestock (n=188) and related farmers (n=94) in Anuradhapura District, Sri Lanka...
September 2017: Germs
Masoumeh Bagheri-Nesami, Mohammad Sadegh Rezai, Fatemeh Ahangarkani, Alireza Rafiei, Attieh Nikkhah, Gohar Eslami, Kheironesa Shafahi, Azin Hajalibeig, Rezvan Khajavi
INTRODUCTION: Ventilator-associated pneumonia (VAP) due to non-fermenting Gram-negative bacilli (NFGNB), especially Pseudomonas aeruginosa and Acinetobacter spp., is one of the main hospital-acquired infections leading to mortality and morbidity, especially in intensive care units (ICUs). This study seeks to determine the multidrug and co-resistance (MDR) patterns of NFGNB that are agents of VAP, and assess the presence of class 1 integron in these bacteria. METHODS: This cross-sectional study involved VAP patients admitted in the ICUs of 18 hospitals in the Mazandaran province, located in the North of Iran...
September 2017: Germs
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