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Facts, Views & Vision in ObGyn

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https://www.readbyqxmd.com/read/29209490/the-importance-of-recognizing-paraneoplastic-symptoms-a-case-report-of-neuroendocrine-small-cell-carcinoma-of-the-endometrium-presenting-as-paraneoplastic-cushing-s-syndrome
#1
A Doukhopelnikoff, G Debrock, T Steelandt, Etm De Jonge
This is the second well documented case of paraneoplastic Cushing's syndrome arising from a small cell carcinoma of the endometrium described in English literature. This tumour has an aggressive biological behaviour and early detection provides the only opportunity for long-term survival. In that regard recognition of associated paraneo- plastic features might be helpful.
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29209489/primary-umbilical-endometriosis-a-case-report
#2
Dpa Van den Nouland, M Kaur
Primary umbilical endometriosis is a rare phenomenon accounting for 0,4-1,0% of extragenital endometriosis. Despite the fact that it mostly presents as a typical cyclic umbilical discharge coincidental with a palpable mass, the diagnosis is often delayed due to its low prevalence, as was seen in the presented case. The exact pathogenesis is still unclear. The golden standard for diagnosis is histopathological examination, but diagnostic tools like ultrasound, MRI or CT scan can be helpful. The differential diagnosis includes a wide range of disorders...
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29209488/education-early-screening-and-treatment-of-stis-could-reduce-infertility-among-women-in-kenya
#3
EDITORIAL
S M Musundi
In Kenya, sexually transmitted infections (STIs) such as Chlamydia trachomatis, Neisseria gonorrhoea, HIV, herpes simplex virus type 2 (HSV-2), syphilis and trichomoniasis tend to be prevalent, especially in women. Further, the research shows that women who test positive for STIs (other than HIV), have little knowledge of these infections. Of particular concern, is that there has been little attention on the part of government to educate the general public about STIs, yet these diseases can have devastating consequences on women's and men's health...
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29209487/first-steps-of-laparoscopic-surgery-in-a-sub-saharan-african-setting-a-nine-month-review-at-the-douala-gynaeco-obstetric-and-pediatric-hospital-cameroon
#4
J T Fouogue, F Y Fouelifack, J H Fouedjio, R Tchounzou, Z Sando, E T Mboudou
Objectives: To describe the first laparoscopic surgeries in a tertiary hospital in Cameroon. Methods: We carried out a descriptive study at the Douala Gynaeco-Obstetric and Pediatric Hospital (DGOPH). We examined the files of the 45 patients who underwent laparoscopic surgery from November 1, 2015 to July 31, 2016. Descriptive statistics were computed for patients' characteristics and surgical parameters. Results: Mean (SD) age was 36.8(11...
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29209486/impact-of-the-angle-used-in-2d-ultrasonography-on-the-foetal-femur-diaphysis-measurement
#5
Anouck Lincé, Xavier Capelle, SyLvie Lepage, Frédéric Kridelka, Christine Van Linthout
Objective: The purpose of this pilot study is to compare the 2D scanning measurement of the foetal femoral diaphysis using anterior or lateral/external incidence at ultrasound. Methods: In August 2016, 30 consecutive patients underwent a second trimester morphology ultrasound between 21 and 24 weeks of gestation by a senior sonographist. In each case, the femur length was measured either with an anterior angle, estimating the straight aspect of the diaphysis or with a lateral angle, assessing its curved aspect...
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29209485/influence-of-bmi-and-smoking-on-iui-outcome-with-partner-and-donor-sperm
#6
S Huyghe, A Verest, A Thijssen, W Ombelet
There is limited literature on the influence of smoking and BMI on success rates after intrauterine insemination (IUI). As a result of a prospective cohort study we could investigate data from 1401 IUI cycles with partner semen and 1264 IUI cycles with donor semen, primary outcome being clinical pregnancy rate (CPR). Univariate statistical analysis showed significant influence of female BMI on clinical pregnancy in the partner insemination group (CPR of 6,5%, 8%, 16,3% and 9,4% for a female BMI < 20, 20-24...
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29209484/correlation-between-saliva-and-serum-concentrations-of-estradiol-in-women-undergoing-ovarian-hyperstimulation-with-gonadotropins-for-ivf-icsi
#7
C Dielen, T Fiers, S Somers, E Deschepper, J Gerris
Aim of the study: To examine saliva- and serum concentrations correlation of estradiol (E2) in women undergoing ovarian hyperstimulation for IVF/ICSI. Saliva measurements could simplify stimulation follow up. A 'home' test for E2 could be useful. Methods: Prospective interventional academic monocentric study at the Centre for Reproductive Medicine of the University Hospital of Ghent, Belgium. Between November 2014 and August 2015 thirty-one patients were included after random selection (inclusion criteria: < 41 years of age, any rank of IVF/ICSI cycle, serum anti- Müllerian hormone concentration ≥ 1 μg/L, treatment completely at the University Hospital...
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29209483/guiding-histological-assessment-of-uterine-lesions-using-3d-in-vitro-ultrasonography-and-stereotaxis
#8
Lieselore Vandermeulen, Ann Cornelis, Christina Kjaergaard Rasmussen, Dirk Timmerman, Thierry Van den Bosch
Objective: To compare ultrasonographic features of uterine lesions with the findings at macroscopy and microscopy. Methods: Case series of ten consecutive women undergoing a hysterectomy for uterine pathology. A preoperative transvaginal ultrasound examination was performed. After hysterectomy, the uterus was re-evaluated by 3D in vitro ultrasonography and in vitro gel instillation sonography (iGIS). The lesion of interest was pinpointed by inserting an intramuscular injection needle using a free-hand 2D-ultrasound guided technique to focus the macroscopic and the microscopic examination by the pathologist...
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29209482/the-place-for-prophylactic-cerclage-in-the-infertile-patient-with-established-cervical-incompetence-who-conceived-twins-after-septum-reduction
#9
Jennifer Deanna, Omar Abuzied, Fahmi Islam, Ivana Vettriano, Frederico Rocha, Mostafa Abuzeid
Introduction: It is well known that cervical incompetence and associated preterm birth confers greater morbidity and mortality on birth outcomes, with an additional increased risk of cervical incompetence in higher order gestations. While the pathophysiology of cervical incompetence has yet to be elucidated, research has identified risk factors and assessed outcomes of numerous interventions. Cervical cerclage has been shown, in certain situations involving singleton pregnancies, to improve outcomes...
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29209481/endoscopic-surgery-one-picture-worth-thousand-words
#10
EDITORIAL
Arnoud Wattiez
No abstract text is available yet for this article.
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/29209480/the-introduction-of-a-video-corner-in-facts-view-vision-why-and-when
#11
EDITORIAL
Vasilis Tanos, Rudi Campo, Willem Ombelet
No abstract text is available yet for this article.
June 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28721185/the-smooth-and-bumpy-road-of-trastuzumab-administration-from-intravenous-iv-in-a-hospital-to-subcutaneous-sc-at-home
#12
Waa Tjalma, M T Huizing, K Papadimitriou
Trastuzumab has become standard of care in the treatment of early and metastatic HER2-positive breast cancer. Initially trastuzumab could only be administered intravenously (IV), however since a few years there is also a subcutaneous (SC) formulation. The efficacy and the safety profile of both formulations is the comparable. The administration logistics however have an impact on the patients, the health care professionals (HCPs), the hospital and the government. The preference for the patients (89%) and the HCPs (77%) is in favour of the SC formulation...
March 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28721184/axillary-lymph-node-dissection-on-the-run
#13
N Maeseele, J Faes, T Van de Putte, J Vlasselaer, E de Jonge, J C Schobbens, K Deraedt, G Debrock, G Van de Putte
The standard approach of performing a completion axillary lymph node dissection (cALND) after a positive sentinel node for breast cancer patients is no longer generally accepted. This study applied the criterion of a 27% risk of having residual positive lymph nodes calculated by the MD Anderson nomogram to perform a cALND. This 27% cut-off is based on the number of positive non-sentinels in the Z0011 trial. A cohort of 166 cN0, sentinel positive breast cancer patients was used to validate the MD Anderson nomogram...
March 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28721183/infertility-in-the-global-south-raising-awareness-and-generating-insights-for-policy-and-practice
#14
T Gerrits, F Van Rooij, T Esho, W Ndegwa, J Goossens, A Bilajbegovic, A Jansen, B Kioko, L Koppen, S Kemunto Migiro, S Mwenda, H Bos
Infertility is a highly prevalent reproductive health condition in the global South, which often has a devastating impact on the people concerned. Yet, thus far it hardly received any attention from policy makers, Non-Governmental Organizations (NGOs) or donors working in the field of Sexual and Reproductive Health and Rights (SRHR). For this reason we have set up a project to increase knowledge and awareness about infertility and childlessness among those stakeholders and organizations and to generate insight into (possible) interventions in this field...
March 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28721182/mitochondria-in-oocyte-aging-current-understanding
#15
REVIEW
D Zhang, D Keilty, Z F Zhang, R C Chian
The oocyte is the largest cell found in multicellular organisms. Mitochondria, as the energy factories for cells, are found in high numbers in oocytes, as they provide the energy for oocyte maturation, fertilization, and embryo formation via oxidative phosphorylation. Failure of assisted reproduction is mainly attributed to oocyte aging and increased aneuploidy. As the most numerous organelle in the oocyte, the mitochondrion has been confirmed as a crucial player in the process of oocyte aging, which is highly influenced by mitochondrion dysfunction...
March 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28721181/adding-sildenafil-vaginal-gel-to-clomiphene-citrate-in-infertile-women-with-prior-clomiphene-citrate-failure-due-to-thin-endometrium-a-prospective-self-controlled-clinical-trial
#16
A N Fetih, D M Habib, I I Abdelaal, M Hussein, G N Fetih, E R Othman
We aimed to investigate the effect of adding sildenafil vaginal gel to clomiphene citrate (CC) in infertile women with prior CC failure. METHODS: This is a self- controlled clinical trial. Women with CC failure (in prior 5 cycles) and thin endometrium were recruited (N = 42). In their 6th (CC only) cycle, women continued on CC 100 mg/ day for 5 days, and had measurement of endometrial thickness and Doppler assessment of uterine arteries on day of HCG administration. In the 7th cycle, women (N = 36) were given usual dose of CC supplemented with sildenafil vaginal gel (5 gm, containing 50 mg sildenafil) twice daily from cycle day 8 to day of HCG administration...
March 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28721180/adenomyosis-back-to-the-future
#17
Z Ferraz, N Nogueira-Martins, F Nogueira-Martins
Adenomyosis is a benign invasion of endometrium into the myometrium. It produces a diffusely enlarged uterus and predominantly affects women in the late reproductive age. It has recently been associated with a negative impact on female fertility. Diagnosis is challenging because nonspecific symptoms can be present. However, it is asymptomatic in the majority of women. Medical treatment with GnRH agonist seems to be promising, particularly in subfertile women. A retrospective study was performed (182 patients) by examination of histopathological results with "adenomyosis" between January/2013 and September/2016...
March 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28721179/early-and-late-onset-complications-of-gynaecologic-surgery-a-multimodality-imaging-approach
#18
REVIEW
I De Blasis, V Vinci, M E Sergi, F Capozza, M Saldari, F Moro, M C Moruzzi, A C Testa, L Manganaro
The role of imaging after surgery is pivotal to drive clinical management of early and/or late onset complications. Most frequently used imaging technique after pelvic surgery is Ultrasound (US), Magnetic Resonance Imaging (MRI) and Computed Tomography (CT). While Ultrasound is a standard procedure, using grey scale and/or colour Doppler evaluation, MRI and CT scan protocols should be derived on the basis of the specific indication of the exam. Correct evaluation of female pelvis after gynaecologic surgery, having in mind the most frequent complications, is based on the correct use of the instruments and on the experience of the examiner, who should be aware of the history of the patient, type of surgery and clinical symptoms for which the exam is required; the clinician should be aware of the possibilities and limits of the different techniques, in order to choose the most appropriate imaging modality and promptly make a correct diagnosis...
March 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28721178/global-reproductive-health-why-do-we-persist-in-neglecting-the-undeniable-problem-of-childlessness-in-resource-poor-countries
#19
EDITORIAL
W Ombelet, J Goossens
The consequences of involuntary childlessness in developing countries create more wide-ranging societal problems compared to Western societies, particularly for women. Negative psychosocial and economical consequences for childless couples are often severe and underestimated by the local and international society. Infertility treatment is often limited to certain procedures and certain costumers. Most common arguments against supporting infertility care in resource-poor countries are the "overpopulation" and the "limited resources" argument, but they totally neglect the reproductive rights and systematic exclusion of millions of women from the right to reproduce...
March 2017: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28210484/in-the-arab-bedroom-the-sex-life-of-arabs
#20
P Dupont
The sex life of Arabs is terra incognita for scientists and policy makers. Shereen El Feki's book "Sex and the Citadel" is the first serious attempt to chart sexual intimacy in the rapidly changing Arab world.
December 2016: Facts, Views & Vision in ObGyn
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