Pezhman Alavinejad, Morteza Nayebi, Abazar Parsi, Eman Abdelsameea, Mohammed Hussien Ahmed, Ahmad Hormati, Dao Viet Hang, Mehdi Pezeshgi Modarres, Bahman Cheraghian, Siamak Baghaee, Tahmine Farbod Ara, Quang Trung Tran, Nitin Shanker Behl, Seyed Jalal Hashemi, Mohammed Alboraie, Saif Salman, Le Nha, Árpád V Patai, Eskandar Hajiani, Ali Akbar Abravesh
Background: The ideal combination regimen for Helicobacter pylori (HP) eradication has not yet been determined and the success rate of HP eradication has been extensively reduced worldwide due to increasing antibiotic resistance. So this multinational multi-center randomized controlled trial was designed to evaluate the efficacy of tetracycline +levofloxacin for HP eradication. Methods: During a 6-month period, all of the cases with HP infection in eight referral tertiary centers of three countries were included and randomly allocated to receive either tetracycline + levofloxacin or clarithromycin plus amoxicillin quadruple regimen for two weeks...
January 2023: Middle East Journal of Digestive Diseases