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Gastroenterology and Hepatology From Bed to Bench

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https://www.readbyqxmd.com/read/28702142/recent-advances-in-nutrition
#1
Dominic King, David Aldulaimi
No abstract text is available yet for this article.
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702141/the-necessity-of-gut-microbiome-characterization-in-diseases-prevention-and-therapy
#2
Sama Rezasoltani, Ehsan Nazemalhosseini Mojarrad, Mohsen Norouzinia, Hamid Asadzadeh Aghdaei
No abstract text is available yet for this article.
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702140/acute-epstein-barr-virus-hepatitis-without-mononucleosis-syndrome-a-case-report
#3
Afshin Moniri, Payam Tabarsi, Majid Marjani, Zahra Doosti
Elevated liver enzymes accompanied by Infectious Mononucleosis syndrome are widely seen in primary Epstein-Barr virus infection while acute symptomatic hepatitis without typical presentations of EBV is extremely rare. In the following report, we present a patient with acute isolated hepatitis due to laboratory confirmed Epstein-Barr virus.
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702139/ramipril-associated-cholestasis-in-the-setting-of-recurrent-drug-induced-liver-injury
#4
David Forner, Tasha Kulai, Thomas Arnason, Steven E Gruchy, Magnus MacLeod
Aim: Angiotensin-converting enzyme inhibitors (ACEIs) are commonly used to treat hypertension. Although generally well tolerated, the adverse effects of ACEIs include hypotension, cough, acute kidney injury and hyperkalemia. Rare reports of ACEI-induced hepatotoxicity have been described, most notably a cholestatic pattern of injury related to captopril. A 67-year-old male presented to the emergency department with a three-week history of jaundice, pruritis and weakness. Eight weeks before, he began taking ramipril and clopidogrel...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702138/prevalence-and-clinical-features-of-cryptosporidium-infection-in-hemodialysis-patients
#5
Mohammad Ali Mohaghegh, Seyed Hossein Hejazi, Mohsen Ghomashlooyan, Hamed Kalani, Farzaneh Mirzaei, Mehdi Azami
AIM: This cross-sectional study aims to assess the prevalence of Cryptosporidium in hemodialysis patients compared with healthy individuals in central Iran from August 2014 to January 2015. BACKGROUND: Cryptosporidiosis is a major cause of acute and persistent diarrhea with significant morbidity and mortality in immunocompromised patients such as those undergoing renal dialysis. METHODS: Three stool samples were collected from 330 hemodialysis patients and 150 healthy individuals on 3 consecutive days...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702137/phage-therapy-assessment-of-the-efficacy-of-a-bacteriophage-isolated-in-the-treatment-of-salmonellosis-induced-by-salmonella-enteritidis-in-mice
#6
Farhad Nikkhahi, Mohammad Mehdi Soltan Dallal, Mahmood Alimohammadi, Abbas Rahimi Foroushani, Zahra Rajabi, Fatemeh Fardsanei, Seyed Mostafa Imeni, Parisa Torabi Bonab
AIM: This work aims to isolate and perform comparative studies of a phages active against a Salmonella enteritidis strain from Iran. Also, suitable phage candidates for therapy of mice will be selected. BACKGROUND: Bacteriophage is of particular interest as a biocontrol agent in the prevention of food-borne illnesses. In recent years tend to use bacteriophages to control pathogenic bacteria has increased. A bacteriophage is considered to be a potent antibiotic alternative for treating bacterial infections...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702136/chronic-cholecystitis-in-the-pediatric-population-an-underappreciated-disease-process
#7
Brian P Blackwood, Julia Grabowski
AIM: We hypothesize that chronic cholecystitis accounts for the majority of inflammatory diseases in the pediatric population and it is difficult to predict with preoperative ultrasound. BACKGROUND: Despite the increase in gallbladder disease, there is a paucity of data on pediatric cholecystitis. Most pediatric studies focus on cholelithiasis and biliary dyskinesia rather than inflammatory gallbladder disease. METHODS: We performed a single center retrospective review of all patients who underwent cholecystectomy from 1/1/10 - 1/1/15...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702135/effect-of-tgf-%C3%AE-smad-signaling-pathway-blocking-on-expression-profiles-of-mir-335-mir-150-mir-194-mir-27a-and-mir-199a-of-hepatic-stellate-cells-hscs
#8
Parivash Davoodian, Mehrdad Ravanshad, Seyed Younes Hosseini, Sayyad Khanizadeh, Mohammad Almasian, Azim Nejati Zadeh, Hamed Esmaiili Lashgarian
AIM: The aim of this study was to determine the effect of inhibition of TGF-β/smad signaling on the expression profiles of miR-335, miR-150, miR-194, miR-27a, miR-199a of hepatic stellate cells (HSCs). BACKGROUND: Liver fibrosis is excessive deposition of extracellular matrix proteins due to ongoing inflammation and HSC activation that occurs in most types of chronic liver diseases. Recent studies have shown the importance of microRNAs in the pathogenesis of chronic liver diseases...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702134/evaluating-the-frequency-of-mlh-1-loss-in-serrated-polyps-of-colon-a-single-center-study-from-southern-iran
#9
Bita Geramizadeh, Nooshin Dindar, Samirasadat Hasheminasab, Tahere Haeidari
AIM: Evaluation of the role of MLH-1 loss in serrated polyps of colon in a population of South of Iran. BACKGROUND: There has been extensive change in classification and pathogenesis of serrated polyps of the colon during the last 10 years. The new classification is mostly based on the knowledge of the molecular pathogenesis and the rate of progression to colorectal cancer in these types of polyps. One of the most common and early lesions in molecular pathogenesis of serrated colorectal cancer is loss of MLH-1...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702133/cytotoxic-effect-of-rosemary-extract-on-gastric-adenocarcinoma-ags-and-esophageal-squamous-cell-carcinoma-kyse30-cell-lines
#10
Neamat Karimi, Jalil Rashedi, Behroz Mahdavi Poor, Sepideh Arabi, Maryam Ghorbani, Nahideh Tahmasebpour, Mohammad Asgharzadeh
AIM: The present study was conducted to survey the potential cytotoxic influence of freeze-dried aqueous extract of its fruits on gastrointestinal cell lines, namely AGS (human gastric carcinoma) and KYSE30 (human esophageal squamous cell carcinoma. BACKGROUND: Rosemary (Rosmarinus officinalis) is a wild medicinal plant shown to have anticancer activity. Carnosic and rosmarinic acids are compounds, obtained from it through several extraction methods. METHODS: The aqueous extract of the fruits of R...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702132/measuring-levels-of-osteopontin-as-potential-biomarker-for-hepatocellular-carcinoma-in-syrian-patients
#11
Sara Al-Zoubi, Ahmad Wassouf, Almoutassem Billah Zetoune
AIM: This study aims to evaluate plasma osteopontin (OPN) levels as a potential biomarker for hepatocellular carcinoma (HCC). BACKGROUND: Osteopontin (OPN) is a secreted glycoprotein that is associated with tumorigenesis and metastasis. METHODS: We measured plasma levels of OPN in 26 HCC patients, 27 patients with chronic liver diseases (CLD), and 15 healthy control individuals using a standardized ELISA kit. RESULTS: The mean plasma OPN level was significantly higher in the HCC group than the CLD group or the normal control group (p-value =0...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702131/distribution-pattern-of-colorectal-diseases-based-on-2300-total-colonoscopies
#12
Yousef Bafandeh, Fereshteh Yazdanpanah
AIM: We conducted a cross-sectional study to estimate the prevalence of CRD in our area in East Azerbaijan, Iran. BACKGROUND: Colorectal diseases (CRD) include a broad spectrum that varies from benign lesions to malignant and cancerous masses. CRD can be investigated by colonoscopy. Some of these diseases are highly preventable with timely screening and appropriate planning by the healthcare system. METHODS: This is a hospital-based, cross-sectional study by the Gastroenterology Department on patients who underwent colonoscopy between June 2013 and March 2015 in outpatient clinics at private Shahriyar medical center and Imam Reza University Hospital in Tabriz, East Azerbaijan province, Iran...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28702130/new-insights-in-ibs-like-disorders-pandora-s-box-has-been-opened-a-review
#13
REVIEW
Raffaele Borghini, Giuseppe Donato, Domenico Alvaro, Antonio Picarelli
The most complained gastrointestinal symptoms are chronic diarrhea, bloating and abdominal pain. Once malignancies and inflammatory bowel diseases are excluded, irritable bowel syndrome (IBS) and the so called "IBS-like disorders" should be taken into account. The relationship between IBS as defined by Rome IV criteria and these clinical conditions is sometimes obscure, since many IBS patients identify food as a possible trigger for their symptoms. Here, we discuss IBS and the most common IBS-like disorders (celiac disease, non-celiac gluten sensitivity, fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs), lactose intolerance, small intestinal bacterial overgrowth (SIBO), α-amylase/trypsin inhibitor (ATIs), nickel allergic contact mucositis), focusing on epidemiologic, clinical, diagnostic and therapeutic aspects...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28496942/tgf-%C3%AE-1-polymorphisms-509-c-t-and-915-g-c-and-risk-of-pancreatic-cancer
#14
Faegheh Behboudi Farahbakhsh, Ehsan Nazemalhosseini Mojarad, Pedram Azimzadeh, Faezeh Goudarzi, Amir Houshang Mohammad Alizadeh, Mehrdad Haghazali, Reza Mahmoudi Lamoki, Hamid Asadzadeh Aghdaei
BACKGROUND: Ninety percent of pancreatic cancer patients have less than 5-year overall survival and approximately 50% of cases were diagnosed with metastasis in the time of admission. Previous evidences have demonstrated the strong association between TGF-β1 variations and cancer susceptibility so far. METHODS: A total of 78 patients with pancreatic cancer and 94 healthy controls were enrolled in this case- control study between 2007 and 2012. Genomic DNA was isolated from peripheral blood samples according to phenol chloroform extraction...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28331570/recent-advances-in-endoscopy
#15
Dominic King, David Al Dulaimi
No abstract text is available yet for this article.
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28331569/an-unusual-diagnosis-for-persistent%C3%A2-diarrhoea-and-vomiting
#16
James Nott, Asad Khan, Ravi Madhotra, George MacFaul, Kamran Rostami
Identifying the etiology of chronic diarrhoea might be challenging in some patients, and before a diagnosis is made these patients may spend a substantial length of time with unresolved symptoms leading to uncertainty and anxiety that is severely impairing their life quality. A 45-year-old female was referred by her general practitioner with a 5-year history of increasingly frequent episodes of cyclical diarrhoea, vomiting, abdominal pain and intermittent palpitations. Contrast CT Abdomen/Pelvis revealed a 36x33x46 mm mass in the aorto caval region of her retro-peritoneum, just above the bifurcation...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28331568/lithophagia-as-a-clue-for-celiac-disease-a-case-report-and-literature-review
#17
Mosayeb Shahryar, Iraj Shahramian, Seyed Mohsen Dehghani, NoorMohammad Noori, Maryam Ataollahi
Lithophagia is a type of pica that might be resulted from Iron Deficiency Anemia (IDA) which is the frequent presenting signs of Celiac Disease (CD). A 5-year-old child with a two year history of the lithophagia with a, refractory IDA, abdominal distention and constipation. The child did not grow well and had failure to thrive. With suspicion to CD, TTg IgA level was measured and due to an incearse of TTg IgA level the patients were undergone esophagogastrodeudonoscpy and jejunal biopsy. The biopsy showed severe villous atrophy and an increase in limphoplasma cells...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28331567/what-is-the-best-algorithm-for-investigation-of-acute-lower-gastrointestinal-haemorrhage
#18
Ainkaran Santhirasekaram, Sherif Latif, Easha Arooj, Kamran Rostami, Sauid Ishaq
An 81-year-old male presented with multiple episode of severe PR bleeding over 2 days. CTA done prior to catheter angiography that enabled successful intervention. This case emphasises the importance of CTA prior to catheter angiography in acute LGIB.
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28331566/person-centered-prediction-of-survival-in-population-based-screening-program-by-an-intelligent-clinical-decision-support-system
#19
Reza Safdari, Elham Maserat, Hamid Asadzadeh Aghdaei, Amir Hossein Javan Amoli, Hamid Mohaghegh Shalmani
AIM: To survey person centered survival rate in population based screening program by an intelligent clinical decision support system. BACKGROUND: Colorectal cancer is the most common malignancy and major cause of morbidity and mortality throughout the world. Colorectal cancer is the sixth leading cause of cancer death in Iran. In this survey, we used cosine similarity as data mining technique and intelligent system for estimating survival of at risk groups in the screening plan...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28331565/evaluation-of-prognostic-factors-effect-on-survival-time-in-patients-with-colorectal-cancer-based-on-weibull-competing-risks-model
#20
Soraya Moamer, Ahmadreza Baghestani, Mohamad Amin Pourhoseingholi, Nastaran Hajizadeh, Farzaneh Ahmadi, Mohsen Norouzinia
AIM: The aim of this study was to assess the association between survival of patients with colorectal cancer and prognostic factors in a competing risk parametric model using Weibull distribution. BACKGROUND: The prognosis of colorectal cancer is relatively good in terms of survival time. In many prognostic studies, patients may be exposed to several types of competing events. These different causes of death are called competing risks. METHODS: Data was recorded from 372 patients with colorectal cancer who registered in the Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences (Tehran, Iran) from 2004 to 2015 in a retrospective study...
2017: Gastroenterology and Hepatology From Bed to Bench
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