journal
Journals International Journal of Hemat...

International Journal of Hematology-oncology and Stem Cell Research

https://read.qxmd.com/read/38076783/myeloid-sarcoma-case-series-with-unusual-locations
#1
Akram Abedi, Nasrin Namdari, Ahmad Monabati, Akbar Safaei, Parvin Rajabi, Maral Mokhtari
Myeloid sarcoma (MS) or chloroma is a localized mass composed of blastic cells of granulocytic lineage. It is a subtype of acute myeloid leukemia and usually presents as a complication of acute myeloid leukemia, myeloid dysplastic syndrome, or myeloproliferative disorder. MS occurs in 2.5-9.1% of patients with AML, precedes the clinical disease, coincidence with the onset or at relapse and in rare conditions, it can occur with no evidence of hematologic disorders. Here, we presented seven cases of MS in unusual locations or with rare presentations at presentation or relapse...
October 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/38076782/adherence-to-immunosuppressants-among-adult-patients-after-allogeneic-hematopoietic-stem-cell-transplantation-allo-hsct-a-cross-sectional-study
#2
JOURNAL ARTICLE
Atefe Derakhshan, Ava Mansouri, Aarefeh Jafarzadeh Kohneloo, Molouk Hadjibabaie
Background: The level of adherence to drug therapy after allogeneic hematopoietic stem-cell transplantation (Allo-HSCT) can affect the patient's outcome, and poor adherence is one of the factors in first-year mortality after HSCT. Material and Methods: This study assessed adherence to cyclosporine and prednisolone as the immunosuppressant regimen in 110 post-HSCT patients (> 18 years). Demographic characteristics, clinical information, and cyclosporine levels were obtained. A validated Persian medication adherence scale was used to assess adherence to cyclosporine and prednisolone...
October 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/38076781/combined-haploidentical-hematopoetic-stem-cell-transplantation-and-liver-transplantation-in-a-pediatric-patient
#3
Vedat Uygun, İbrahim Aliosmanoğlu, Hayriye Daloğlu, Seda Öztürkmen, Koray Yalçın, Gülsün Karasu, Akif Yeşilipek
Solid organ transplantation from the same donor is an established procedure for end-stage organ failure that developed after a previous hematopoietic stem cell transplantation (HSCT); however, it is rarely done in patients transplanted with unmanipulated haplo-HSCT. There are no pediatric reports regarding the long-term performance of organ transplantation after haplo-HSCT with post-transplant cyclophosphamide (PTCY). A juvenile myelomonocytic leukemia patient, who underwent unmanipulated haplo-HSCT with PTCY from her mother at the age of 3 years, developed chronic liver graft versus host disease (GvHD) which was refractory to specific GvHD treatment...
October 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/38076780/cytoplasmic-ccr7-ccr7c-immunoexpression-is-associated-with-tumor-invasion-in-gastric-cancer
#4
JOURNAL ARTICLE
Laleh Vahedi, Somayeh Sheidaei, Maryam Ghasemi, Kolsumeh Ebrahimi, Jamshid Yazdani Cherati
Background : This study investigates the CCR7 chemokine receptor's prognostic value in gastric cancer and its relationship to metastasis. Materials and Methods : Normal and adjacent tumor cells in 70 patients with gastric cancer were evaluated for CCR7 expression using immunohistochemical staining. The prognostic values of high and low levels of expression of CCR7 were also evaluated by multivariate and univariate analyses. Results : Analysis indicated high expression of CCR7 in 52.9% of tumor tissue. Moreover, high expression of CCR7 was significantly related to metastasis of lymph nodes (p = 0...
October 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/38076779/antitumor-activity-of-ziziphus-jujube-fruit-extracts-in-kg-1-and-nalm-6-acute-leukemia-cell-lines
#5
JOURNAL ARTICLE
Shiva Mosadegh Manshadi, Mohammad Reza Shams Ardekani
Background : Ziziphus jujube Mill . belongs to the Rhamnaceae family. It has been reported to have a variety of biological activities such as antitumor, antioxidant, and anti-inflammatory effects. This study investigates the antiproliferative effect of Ziziphus jujube on KG-1 and NALM-6 acute leukemia cell lines. Materials and Methods : In this experimental study, the aqueous, ethyl acetate, and hydroalcoholic extracts of the Ziziphus jujube were prepared. Total phenolic and flavonoid components were detected because the presence of these compounds is associated with antioxidant and anticancer effects...
October 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/38076778/a-study-of-association-of-abo-and-rh-blood-group-with-colorectal-cancer-in-khuzestan-province-iran
#6
JOURNAL ARTICLE
Hosein Jodat, Javad Jodat, Ali Khodadadi, Abdolhassan Talaiezadeh, Nazanin Joudaki, Ali Asadirad
Background : Colorectal cancer, a solid tumor with a high prevalence, contributes significantly to annual mortality rates. Various factors, including blood groups, may influence cancer risk. Multiple studies have suggested a potential connection between ABO and Rh blood groups and colorectal cancer risk. This study aims to investigate the role of ABO and Rh blood groups as risk factors in colorectal cancer patients. Materials and Methods: We conducted a retrospective study involving 71 colorectal cancer patients diagnosed between 2018 and 2020 in Khuzestan province, Iran, with known ABO blood types...
October 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/38076777/no-association-of%C3%A2-as3mt-gene-polymorphisms-with-susceptibility-to-hepatotoxicity-in-apl-patients-treated-with-as2o3-a-single-center-study
#7
JOURNAL ARTICLE
Zeinab Joneidi, Yousef Mortazavi, Bahram Chahardouli, Shahrbano Rostami, Mohammad Vaezi, Majid Nabipour, Alireza Biglari, Ardeshir Ghavamzadeh
Background: Arsenic three oxide (As2O3) is the treatment choice for acute promyelocytic leukemia (APL). Little is known about possible risk factors with predictive value for toxicity caused by As2O3. Biomethylation is considered to be a major pathway of detoxification for inorganic arsenics (iAs). Arsenic Methyltransferase (AS3MT) is one of the key enzymes involved in the transfer of a methyl group from S-adenosyl-L-methionine to trivalent arsenical and plays a critical role in arsenic detoxification...
October 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/38076776/developing-a-multichannel-bioreactor-with-a-collagen-scaffold-ecm-and-cryoprecipitate-to-significantly-produce-platelets-from-umbilical-cord-blood-stem-cells
#8
JOURNAL ARTICLE
Mohamad Hosein Derakhty Gonbad, Ali Baradar Khoshfetrat, Ali Akbar Movassaghpour, Zohre Sanaat, Hojjatollah Nozad Charoudeh
Background: Platelets play a key role in the treatment of thrombocytopenia. Nowadays, platelets (PLTs) are only obtained through blood donation. However, due to the limitations in their preparation and storage, they are produced in laboratories, especially through bioreactors that convert megakaryocytes from stem cells into large-scale injectable PLTs. Materials and Methods: In this study, the CD34 cells isolated from cord blood were differentiated into megakaryocytes. A 6-chamber bioreactor with a two-layer collagen scaffold, several ECM factors, and human cryoprecipitate were used to simulate the structure of the bone marrow...
October 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/38076775/evaluation-of-serum-vitamin-b12-levels-in-patients-with-colon-and-breast-cancer-a-case-control-study
#9
JOURNAL ARTICLE
Ghazaleh Haghighat, Ahmad Khajeh-Mehrizi, Hossein Ranjbar
Background: It has been shown that increased serum levels of vitamin B12 may be associated with some malignancies. This study aimed to compare the serum levels of vitamin B12 in patients with colon and breast cancer and healthy individuals. Materials and Methods: In this case-control study, 140 patients with colon and breast cancer were compared with 140 healthy individuals matched in age, gender, and socioeconomic status. Serum levels of vitamin B12 were measured through the Electrochemiluminescence method in both groups...
October 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/38076774/correlation-of-magnesium-level-with-cardiac-and-hepatic-hemosiderosis-measured-by-t2-mri-technique-and-age-in-patients-with-thalassemia-major
#10
JOURNAL ARTICLE
Ali Ghasemi, Kazem Ghaffari, Fatemeh Hoseini, Aziz Eghbali, Nooshin Sajadei, Vahid Falahati, Yazdan Ghandi
Background: Given the association of hypomagnesemia with cardiac arrhythmia, the aim of this study was to investigate the relationship between serum magnesium levels with age and T2* magnetic resonance imaging (MRI) findings of the heart and liver in patients with thalassemia major (TM). Materials and Methods: In a descriptive cross-sectional study, a total of 62 patients with β-thalassemia major aged 11-48 years were selected at the Amir-Kabir Hospital, Arak, Iran. Serum magnesium, ferritin, and iron levels of patients were measured, and the rate of cardiac and hepatic hemosiderosis of patients was extracted according to the routine T2*MRI method...
October 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/37817975/prevalence-of-androgen-receptor-in-invasive-breast-cancer-and-its-association-with-clinicopathologic-features-in-east-azarbaijan-province-of-iran-a-cross-sectional-study
#11
JOURNAL ARTICLE
Alireza Nikanfar, Mahsa Nikanfar, Ashraf Fakhrjou
Background: Breast cancer is the most common malignancy and the leading cause of cancer-related deaths in females. Accordingly, the evaluation of new prognostic markers and therapeutic targets is of vital importance. Here, we aimed to detect androgen receptor (AR) status and define its association with clinicopathologic parameters in patients with invasive breast cancer. Materials and Methods: In this study, AR status was studied in 104 patients with invasive breast carcinoma by immunohistochemistry. Besides, its association with clinicopathologic factors, i...
July 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/37817974/assessment-of-standard-operating-procedures-sops-preparing-hygienic-condition-in-the-blood-donation-centers-during-the-outbreak-of-covid-19
#12
JOURNAL ARTICLE
Saeed Mohammadi, Seyed Morteza Tabatabaei Yazdi, Sahar Balagholi, Saeid Saremi, Rasul Dabbaghi, Shirin Ferdowsi, Peyman Eshghi
Background: The coronavirus disease 2019 (COVID-19) outbreak has led to an alteration in hygienic conditions. In this situation, improving standard operating procedures (SOPs) in blood donation centers is critical. The purpose of this study was the assessment of SOPs in the blood donation centers during the outbreak of COVID-19 by regular blood donors as external audits. Materials and Methods: Regular donors were selected as external inspectors in 31 provinces of Iran. The questionnaire containing 10 closed questions was provided to assess the hygienic SOPs of blood transfusion centers in the prevention of COVID-19 transmission...
July 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/37817973/association-of-high-serum-leptin-level-with-papillary-thyroid-carcinoma-a-case-control-study
#13
JOURNAL ARTICLE
Roya Refahi, Zahra Heidari, Mohammadali Mashhadi
Background: Recently, the prevalence of thyroid cancer has increased. Although there are known risk factors for thyroid cancer, none of them can justify this recent increase. In addition to the known risk factors, other risk factors have been proposed. Leptin can be considered as one of these risk factors due to the recent increase in the prevalence of obesity in the population. Leptin is a common factor in obesity and thyroid cancer. Leptin exerts anti-apoptotic and mitogenic effects on cancer cells and also acts as an angiogenic factor...
July 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/37817972/assessment-of-effectiveness-and-adverse-effect-of-new-combination-chemotherapy-irinotecan-cisplatin-and-dexamethasone-in-relapse-and-refractory-hodgkin-lymphoma
#14
JOURNAL ARTICLE
Mahdi Tabarraee, Atefeh Rezaee, Sara Abolghasemi, Mojtaba Ghadiany, Maria Tavakoli Ardakani, Mahshid Mahdizadeh, Neda Hamidi, Katayoon Ghasemi
Background: Chemotherapy with Adriamycin, Bleomycin, Vinblastine, and Dacarbazine (ABVD regimen) cannot cure all patients with Hodgkin lymphoma. In this study, we evaluated the efficacy and adverse effect of a new regimen consist Irinotecan, Cisplatin, and Dexamethasone (ICD) in relapsed and refractory Hodgkin lymphoma as the second to fifth line of treatment. Materials and Methods: We performed a retrospective study in 26 relapsed or refractory patients with Hodgkin lymphoma receiving at least the first-line chemotherapy regimen (ABVD) and (ICD) as salvage therapy in Thaleghany Hospital from 2012 to 2018...
July 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/37817971/the-association-of-methylation-status-and-expression-level-of-myod1-with-dnmt1-expression-level-in-breast-cancer-patients
#15
JOURNAL ARTICLE
Sahar Khojastehpour, Farshad Foroughi, Nematollah Gheibi, Zahra Mohammadi, Mohammad Hossein Ahmadi, Neda Nasirian, Amirhosein Maali, Mehdi Azad
Background: Breast cancer (BC) is the most common malignancy in women worldwide. The methylation status of MyoD1 , a tumor suppressor gene, is enrolled in various cancers, i.e., BC. Various studies showed the impact of MyoD1 epigenetic dysregulation in BC. This study aimed to investigate the methylation status and expression level of MyoD1 in BC patients and its association with the expression of DNMT1 . Materials and Methods: This case-control study was conducted on 30 cases (pathology-confirmed ductal carcinoma) and 18 controls (fibroadenoma and fibrocystic masses), referred to Velayat Hospital, Qazvin, Iran...
July 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/37817970/clinical-features-and-risk-factors-of-relapse-and-mortality-in-thrombotic-thrombocytopenic-purpura-patients-a-seven-year-experience
#16
JOURNAL ARTICLE
Sahar Tavakoli Shiraji, Mohammad Reza Rostami, Hosein Kamranzadeh Foumani, Seied Asadollah Mousavi, Mohammad Vaezi, Soroush Rad, Davood Babakhani, Maryam Barkhordar, Tanaz Bahri, Ghasem Janbabaei, Ashraf Malekmohammadi, Saeed Mohammadi, Vahid Mansouri
Background : Thrombotic thrombocytopenic purpura (TTP) is associated with microangiopathic hemolytic anemia, thrombocytopenia, and microvascular thrombosis. No comprehensive report exists on clinical characteristics and risk factors of relapse and mortality in Iranian TTP patients. In this study, we aimed to report clinical features of Iranian TTP patients, to evaluate disease relapse and mortality rate and their associated risk factors. Materials and Methods : This study was a cohort study of patients diagnosed with microangiopathic hemolytic anemia admitted to the Shariati Hospital, Tehran, a referral center for TTP patients, from 2010 to 2017...
July 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/37817969/pernicious-anemia-following-covid-19-vaccination-a-report-of-two-cases
#17
Hamidreza Soltani, Saeb Taghizade, Abdolrahim Sadeghi, Ali Farahat, Mohammad Bagher Owlia
Since December 2019 and the global epidemic of COVID-19 different countries have focused on vaccines, and one of the inactivated produced vaccines was the Sinopharm COVID-19 vaccine. Some side effects of this vaccine were reported previously, including pain at the vaccination site, fatigue, lethargy, headache, and tenderness, which were more prevalent among individuals <49 years old. Herein, we reported two patients aged 45 and 51 years old. Both patients have different signs and symptoms after receiving the second dose of the vaccine...
July 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/37817968/involvement-value-of-flt-3-c-myc-stat3-p27-and-hotair-gene-expression-in-acute-myeloid-leukemia-patients-a-molecular-perspective-to-a-novel-leukemogenesis-mechanism
#18
JOURNAL ARTICLE
Naser Shagerdi Esmaeli, Shahin Asadi, Davood Bashash, Sina Salari, Mohsen Hamidpour
Background: The identification of long non-coding RNAs (lncRNAs) in the pathogenesis of acute myeloid leukemia (AML) has marked a new era in the molecular understating of the disease. This study investigated the correlation between the changes in the expression of lncRNAs, including HOTAIR, PVT-1, and CRNDE, and the alteration in the expression profile of FLT-3, c-Myc, STAT3, STAT5, and p27 in AML patients. Materials and Methods: Blood samples were collected from forty-one newly diagnosed AML patients and ten healthy individuals to evaluate the expression levels of the study genes using qRT-PCR analysis...
July 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/37817967/blood-products-utilization-status-in-off-pump-cardiac-surgery-patients
#19
JOURNAL ARTICLE
Azita Chegini, Mastaneh Alaei, Afsaneh Jahangiryan, Maryam Zadsar
Background: Transfusion support has an essential role in coronary artery bypass graft (CABG). The time-honored gold standard for CABG is the on-pump procedure (ONCAB); however, off-pump coronary artery bypass (OPCAB) is also a safe, cost-benefit procedure with fewer blood transfusion requirements. This study was performed to evaluate transfusion patterns in OPCAB due to the diversity of transfusion practices. Materials and Methods: This retrospective study was performed to determine the transfusion rate and triggers in OPCAB patients...
July 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
https://read.qxmd.com/read/37817966/the-effect-of-the-persian-gulf-jellyfish-cassiopea-andromeda-venom-on-the-expression-of-p15-p21-p53-dnmt1-and-bcl-2-in-acute-lymphoblastic-leukemia-jurkat-cells
#20
JOURNAL ARTICLE
Reza Dehghani, Ali Amrooni, Fatemeh Hosseinpour-Soleimani, Gholamhossein Mohebbi, Narges Obeidi
Background: One of the acute hematologic malignancies is acute lymphoblastic leukemia (ALL), which is formed in B or T lymphocyte stem cells. Regarding the increasing tendency to herbal and marine studies and unclear characteristics of Cassiopea andromeda Venom, this study was performed to determine its effects on Jurkat cells as a model for T-ALL. Materials and Methods: In this experimental study, the cells were treated with a variety of concentrations of Cassiopea andromeda venom at different periods and times...
July 1, 2023: International Journal of Hematology-oncology and Stem Cell Research
journal
journal
48123
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.