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International Journal of Fertility & Sterility

Ardeshir Bahmanimehr, Shahryar Zeighami, Bahia Namavar Jahromi, Zahra Anvar, Mohammad Ebrahim Parsanezhad, Maryam Davari, Somayeh Montazeri
Background: Y chromosome deletions (YCDs) in azoospermia factor (AZF) region are associated with abnormal spermatogenesis and may lead to azoospermia or severe oligozoospermia. Assisted reproductive technologies (ART) by intracytoplasmic sperm injection (ICSI) and testicular sperm extraction (TESE) are commonly required for infertility management of patients carrying YCDs. The aim of this study was to estimate the frequency of YCDs, to find the most frequent variant in infertile men candidate for ART and to compare YCD distribution with a control fertile group...
July 2018: International Journal of Fertility & Sterility
Meysam Jangkhah, Faramarz Farrahi, Mohammad Ali Sadighi Gilani, Seyed Jalil Hosseini, Farid Dadkhah, Reza Salmanyazdi, Mohammad Chehrazi
Background: The main purpose of this study is to evaluate the effects of varicocelectomy on serum testosterone levels and semen quality in infertile men who suffer from varicocele. MATERIALS AND METHODS: This prospective study enrolled 115 subjects with clinical varicocele grades II and III and 240 fertile men as the control group. Total volume of testosterone serum level (ng/dl) and semen quality were compared before and after microscopic varicocelectomy. We normalized testosterone serum levels for age, grade, and testis size basis...
July 2018: International Journal of Fertility & Sterility
Nafiye Yilmaz, Ebru Ersoy, Aytekin Tokmak, Ayla Sargin, A Seval Ozgu-Erdinc, Salim Erkaya, Halil Ibrahim Yakut
Background: Recent studies have shown that vitamin D has an essential role in the reproductive system. In this study, we aimed to investigate the effect of vitamin D levels in patients undergoing ovulation induction (OI), and subsequent intrauterine insemination (IUI) procedure. MATERIALS AND METHODS: One hundred and four infertile and one hundred and three fertile women were recruited in this cross-sectional study which was conducted in a tertiary level maternity hospital...
July 2018: International Journal of Fertility & Sterility
Saghar Saeedabadi, Amir Hossein Abazari-Kia, Hoda Rajabi, Kazem Parivar, Mohammad Salehi
Background: DNA methylation is one the epigenetic mechanisms, which is critically involved in gene expression. This phenomenon is mediated by DNA methyl-transferases and is affected by environmental stress, including in vitro maturation (IVM) of oocytes. Melatonin, as an antioxidant, may theoretically be involved in epigenetic regulation via reductions of reactive oxygen species. This study was performed to investigate DNA methylation and the possibility of goat oocyte development after treatment with different concentrations of melatonin...
July 2018: International Journal of Fertility & Sterility
Sahar Bagheri, Rasoul Roghanian, Naser Golbang, Pouran Golbang, Mohammad Hossein Nasr Esfahani
Background: Chlamydia trachomatis (CT) infection is the most common sexually transmitted disease in the world that can persist and also ascend in the genital tract. This intracellular and silent infection is related to some adverse pregnancy outcomes, such as miscarriage. The aims of this study were to explore the best CT screening tests using blood and vaginal samples and to investigate the correlation between CT infection and the incidence of miscarriage. MATERIALS AND METHODS: This case-control study was done in October 2013 through June 2014, using purposive sampling from 157 female participants with or without a history of miscarriage...
July 2018: International Journal of Fertility & Sterility
Zohreh Rahimi, Foroogh Chamaie-Nejad, Shohreh Saeidi, Ziba Rahimi, Ali Ebrahimi, Ebrahim Shakiba, Asad Vaisi-Raygani
Background: The aim of present study was to clarify the role of the peroxisome proliferator-activated receptor (PPAR) ╬│ Pro12Ala and C161T polymorphisms in the pathogenesis of polycystic ovary syndrome (PCOS) and their influence on lipid and lipoprotein profiles of patients. MATERIALS AND METHODS: The present cross-sectional study consisted of 50 women with PCOS, who referred to the Kermanshah University of Medical Sciences Clinic between April and October 2015, and 233 unrelated age-matched healthy women from the same region (West Iran)...
July 2018: International Journal of Fertility & Sterility
Abdelhafid Benksim, Noureddine Elkhoudri, Rachid Ait Addi, Abdellatif Baali, Mohamed Cherkaoui
Background: The main objective of this survey was to determine the difference between primary and secondary infertility in Morocco and the associated factors among women, who are referred to public and private health centers in Morocco. MATERIALS AND METHODS: In this cross-sectional study, 619 infertile women referring to public and private health centers in Marrakech-Safi region, were selected by simple random sampling method. This study was conducted between 1 October 2013 and 31 December 2015...
July 2018: International Journal of Fertility & Sterility
Mohammad Sahebalzamani, Zahra Mostaedi, Hojjatollah Farahani, Mobin Sokhanvar
Background: Health science and technology today is a rapidly growing field. Health is a multifaceted concept influenced by several factors, and health literacy is essential to deal properly with the current situation. In this study, the association between health literacy and sexual function and sexual satisfaction were investigated in 2016. MATERIALS AND METHODS: This descriptive and correlational study was conducted on 193 couples in the Royan Institute, Tehran...
July 2018: International Journal of Fertility & Sterility
Asma Tiyuri, Seyyed Abolfazl Vagharseyyedin, Marziyeh Torshizi, Najmeh Bahramian, Morteza Hajihosseini
Background: Infertility is a common clinical problem. Psychological adjustment to infertility refers to changing the viewpoint and attitude of an infertile person toward infertility problems, treatments and possible outcomes. The present study aims to prepare a valid and reliable scale for assessing the psychological adjustment to infertility, by determining the cultural adaptation, validity and reliability of the Persian version of the Fertility Adjustment Scale. MATERIALS AND METHODS: This is a cross-sectional study performed to localize and validate the Fertility Adjustment Scale, in which 40 infertile women and 40 healthy subjects (fertile or having children) were detected by a gynecologist and the subjects who completed the Fertility Adjustment Scale (FAS) questionnaire were recruited...
July 2018: International Journal of Fertility & Sterility
Somayeh Alirezaei, Gity Ozgoli, Hamidreza Alavi Majd
Background: Infertility is a major and problem influencing different aspects of couples life, especially those of women. Sexual dysfunction is the silent partner of infertility. This study aimed to identify the above-mentioned factors to make necessary decisions and perform efficient interventions to improve the sexual health of infertile women. This study investigated the factors influencing sexual dysfunction in infertile women in Mashhad, Iran. MATERIALS AND METHODS: This cross-sectional study was conducted on 85 infertile women visiting governmental Infertility Clinic and Research Center in Mashhad, Iran...
July 2018: International Journal of Fertility & Sterility
Behnaz Navid, Maryam Mohammadi, Saman Maroufizadeh, Payam Amini, Zahra Shirin, Reza Omani-Saman
Background: Many infertile couples experience psychological distress and suffer from impaired quality of life. Generally, when couples are dealing with uncontrolled events such as infertility, it is important to manage it well and to use the suitable coping style; so this can represent an example of attribution style. The purpose of this study is to investigate the quality of life, relationship beliefs and attribution style in infertile couples. MATERIALS AND METHODS: This cross-sectional study consisted of 50 infertile couples, who were at least 18 years of age and could read and write in Persian...
July 2018: International Journal of Fertility & Sterility
Samira Vesali Vesali, Elaheh Karimi, Maryam Mohammadi, Reza Omani-Samani
Background: Among the young generation, medical and law students' attitude towards third party reproduction is very important because they will be directly involved in restricting or developing the programs that will support it in the future. The aim of this survey was to investigate attitude of law and medical students to oocyte donation and key aspects of this kind of third party. MATERIALS AND METHODS: In analytical cross-sectional study, 345 medical and law students were randomly selected using stratified sampling...
July 2018: International Journal of Fertility & Sterility
Payam Amini, Abbas Moghimbeigi, Farid Zayeri, Hossein Mahjub, Saman Maroufizadeh, Reza Omani-Samani
Background: Abnormalities in birth weight and gestational age cause several adverse maternal and infant outcomes. Our study aims to determine the potential factors that affect birth weight and gestational age, and their association. MATERIALS AND METHODS: We conducted this cross-sectional study of 4415 pregnant women in Tehran, Iran, from July 6-21, 2015. Joint multilevel multiple logistic regression was used in the analysis with demographic and obstetrical variables at the first level, and the hospitals at the second level...
July 2018: International Journal of Fertility & Sterility
Arezoo Shayan, Masumeh Taravati, Maryam Garousian, Narges Babakhani, Javad Faradmal, Seyedeh Zahra Masoumi
Background: Marital quality reflects the individual's overall evaluation of marital relationship. The aim of study was examine the effect of cognitive behavioral counseling on marital quality among women. MATERIALS AND METHODS: The experimental study was a randomized clinical trial with two groups, on 198 qualified women who referred to selected health care centers in Hamadan, Iran in 2016. The intervention participants attended four 90-minute sessions of cognitive behavioral counseling...
July 2018: International Journal of Fertility & Sterility
Maryam Barekat, Shahnaz Ahmadi
Hypertensive disorders (HDs) as the most prevalent medical problem during pregnancy, predispose the patient to a lot of comorbidities and may even cause maternal or fetal death. The rate of infertility has been increasing in recent decades. So, we collected and summarized data about the co-existence of these two entities and found that HDs are somewhat more common in women receiving fertility treatments regardless of pathophysiologic correlation of infertility and hypertension or older age and chance of multiple pregnancies...
July 2018: International Journal of Fertility & Sterility
Mania Kaveh, Kobra Tahermanesh, Abolfazl Mehdizadeh Kashi, Banafsheh Tajbakhsh, G Hazal Mansouri, Kambiz Sadegi
Endometriosis affects about 10% of women of reproductive age. Its main feature is the presence of stroma and endometrial glands in sites other than the uterus, mainly in pelvis. Pelvic peritoneum, ovaries, uterine ligaments, bladder, intestines, andcul-de-sac are among the affected areas. Sometimes endometriosis can be found outside of the pelvis and even above abdominal cavity, like indiaphragm.Herein, we present a case of an asymptomatic diaphragmatic endometriosis that was discovered incidentally during laparoscopy of pelvic endometriosis, as well as our appropriately proposed treatment protocol...
June 2018: International Journal of Fertility & Sterility
Manouchehr Safari, Houman Parsaie, Hamid Reza Sameni, Mohammad Reza Aldaghi, Sam Zarbakhsh
BACKGROUND: Apigenin is a plant-derived compound belonging to the flavonoids category and bears protective effects on different cells. The aim of this study was to evaluate the effect of apigenin on the number of viable and apoptotic blastomeres, the zona pellucida (ZP) thickness and hatching rate of pre-implantation mouse embryos exposed to H2 O2 and actinomycin D. MATERIALS AND METHODS: In this experimental study, 420 two-cell embryos were randomly divided into six groups: i...
June 2018: International Journal of Fertility & Sterility
Amir M Bassam Elnagar, Abdelnasser Ibrahim, Amro Mohamed Soliman
BACKGROUND: Titanium dioxide (TiO2 ) is a white pigment which is used in paints, plastics, etc. It is reported that TiO2 induces oxidative stress and DNA damage. N-acetylcysteine (NAC) has been used to fight oxidative stress-induced damage in different tissues. The objective of this study was to evaluate the toxic effects of orally administered TiO2 nanoparticles and the possible protective effect of NAC on the testes of adult male albino rats. MATERIALS AND METHODS: In this experimental study, 50 adult male albino rats were classified into five groups...
June 2018: International Journal of Fertility & Sterility
Malihe Soltani, Maryam Moghimian, Seyed Hossein Abtahi-Eivari, Hamed Shoorei, Arash Khaki, Majid Shokoohi
BACHGROUND: There is some evidence indicating that Matricaria chamomile (MC) had protective effects on ischemiareperfusion. In the present study, a rat model was used to investigate the effect of hydroalcoholic extract of MC on torsion/detorsion-induced testis tissue damage. MATERIALS AND METHODS: In this experimental study, 28 male Wistar rats were randomly divided into 4 groups as follows: G1, Sham operated; G2, testicular torsion/detorsion (T/D); G3, rats with testicular torsion/detorsion that received 300 mg/kg of MC extracts 30 minutes before detorsion (T/DMC); and G4, healthy rats that received 300 mg/kg of MC extracts (MC)...
June 2018: International Journal of Fertility & Sterility
Mahnaz Poorhassan, Fatemeh Navae, Simin Mahakizadeh, Mahshid Bazrafkan, Banafshe Nikmehr, Farid Abolhassani, Sahar Ijaz, Nazila Yamini, Nasrin Dashti, Kobra Mehrannia, G holamReza Hassanzadeh, Mohammad Akbari
BACHGROUND: Hypoxia causes detrimental effects on the structure and function of tissues through increased production of reactive oxygen species that are generated during the re-oxygenation phase of intermittent and continuous hypobaric hypoxia. This study was carried out to evaluate the effects of flaxseed (Fx) in reducing the incidence of hypoxia in rat testes. MATERIALS AND METHODS: In this experimental study, 24 adult Wistar rats were randomly divided into four groups: i...
June 2018: International Journal of Fertility & Sterility
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