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Current Urology

Mathew Fakhoury, Richard R Hwang, Joseph Silletti, Marc A Bjurlin
It remains evident in the literature that leiomyosarcomas of the bladder have continuously been regarded as highly aggressive tumors associated with a poor prognosis. Immediate surgical therapy by radical cystectomy with wide margins is warranted as an effective treatment modality and has been associated with longer survival rates. Herein, we present the case of a high-grade leiomyosarcoma primarily treated with anterior pelvic exenteration and urinary diversion.
October 2016: Current Urology
William S Gange, Robert H Blackwell, John Biemer, Güliz A Barkan, Maria M Picken, Marcus L Quek
Growing teratoma syndrome is an infrequent presentation of testicular cancer. We present a case of growing teratoma syndrome in a patient who initially presented with clinical stage I nonseminomatous testicular germ cell tumor, who subsequently developed large volume oligometastases to the retroperitoneum, thorax, and thigh. Despite two regimens of chemotherapy, his disease progressed. Complete surgical extirpation of all gross tumors confirmed mature teratoma. An aggressive surgical approach, including postchemotherapy resection of all known metastatic sites, can provide long-term disease-free survival...
October 2016: Current Urology
(no author information available yet)
[This corrects the article DOI: 10.1159/000442846.].
October 2016: Current Urology
Dina J Ludwig, Hossain Roshani, Martijn G Steffens, Frederik C Moll, Robertus G Teepe
Pyoderma gangrenosum is a rare non-infectious skin disorder. It is often associated with systemic diseases, like the inflammatory bowel disease, rheumatological disease and (hematological) malignancy. The diagnosis is affirmed through a process of elimination and is principally based on clinical presentation and course. We present a 59-year-old male with T-cell large granular lymphocyte leukemia and pyoderma gangrenosum of penis and scrotum. Finally the patient was successfully treated with systemic prednisolone...
October 2016: Current Urology
Ali H Yilmaz, Elif Ziypak, Tevfik Ziypak, Mehmet Aksoy, Senol Adanur, Hüseyin Kocakgol, Saban O Demirdogen, Ozkan Polat
INTRODUCTION: To determine whether a combination of the long acting local anesthetic, bupivacaine, and lidocaine is better than lidocaine alone in the long-term pain control, which is a short-acting anesthetic. MATERIALS AND METHODS: In group 1, periprostatic nerve block was applied to both neurovascular areas with 2% lidocaine (5 ml) in an isotonic solution (5 ml). In group 2, the combination of 2% lidocaine (5 ml) and 5mg/ml bupivacaine (5 ml) was used for the PPNB...
October 2016: Current Urology
Saad Elzanaty, Babak Rezanezhad, Rasmus Borgquist
INTRODUCTION: This study was aimed to determine the association between PSA levels and biomarkers of subclinical systemic inflammation based on data from 119 middle-aged healthy men from the general population. MATERIALS AND METHODS: Serum levels of PSA and biomarkers of systemic inflammation (CRP and fibrinogen) were measured. Demographic data were also collected. Subjects were divided into two groups according to PSA levels; < 2 ng/ml and ≥ 2 ng/ml. RESULTS: The mean (SD) age of men was 55 ± 4...
October 2016: Current Urology
Gregory J Nason, Asadullah Aslam, Subhasis K Giri
INTRODUCTION: The aim of this study was to assess whether preoperative multiple detector computed tomography (MDCT) accurately predicts adrenal involvement for patients undergoing non-adrenal sparing radical nephrectomy for renal cell carcinoma. METHODS AND MATERIALS: A retrospective observational study based on a composite patient population of two university teaching hospitals who underwent radical nephrectomy. Sensitivity, specificity, overall accuracy, positive and negative predictive values and likelihood ratios were calculated from radiological reports...
October 2016: Current Urology
Carlo C Passerotti, José A Cruz, Sabrina T Reis, Marcelo T Okano, Ricardo J Duarte, Miguel Srougi, Hiep T Nguyen
OBJECTIVES: Currently, there is no standardized training protocol to teach surgeons how to deal with vascular injuries during laparoscopic procedures. The purpose of this study is to develop and evaluate the effectiveness of a standardized algorithm for managing vascular injury during laparoscopic nephrectomies. MATERIALS AND METHODS: The performance of 6 surgeons was assessed during 10 laparoscopic nephrectomies in a porcine model. During the first and tenth operations, an injury was made in the renal vein without warning the surgeon...
October 2016: Current Urology
Boris Chertin, Alexander Zeldin, Stanislav Kocherov, Alexander Ioscovich, Israel A Ostrovsky, Yaacov Gozal
INTRODUCTION: To test the efficacy and safety of caudal anesthesia (CA) supplemented by low dose morphine in children who undergo renal surgery. MATERIALS AND METHODS: Forty patients aged 2 months-14 years were enrolled and randomly divided into two groups of 20 patients each: Group A (bupivacaine 0.2% with fentanyl); Group B (bupivacaine with morphine). The duration of surgery and hospitalization time were recorded. Postoperative pain score was measured by Face Legs Activity Cry Consolability scale and Wong-Baker Faces scale for those who are older...
October 2016: Current Urology
Kirill V Kosilov, Sergay A Loparev, Marina A Ivanovskaya, Liliya V Kosilova
OBJECTIVE: This study was conducted to compare overactive bladder (OAB) prevalence among people greater than 60 years of age who intake various doses of caffeine, as well as those who abstain from caffeine. PATIENTS AND METHODS: A randomized observational study was carried out in Vladivostok Gerontological Hospital. A total of 1,098 retired people greater than 60 years of age (659 women and 439 men, average age 67.1 years) took part in the study. They were admitted to the in-patient department with the purpose of annual physical examination performed in accordance with the order of the Ministry of Public Health of the Russian Federation...
October 2016: Current Urology
Saad Elzanaty, Babak Rezanezhad, Ronnie Willenheimer, Rasmus Borgquist
INTRODUCTION: Epidemiological studies suggest atherosclerosis as a common risk factor between cardiovascular diseases and erectile dysfunction (ED). We aimed to determine the association between erectile function and the biomarkers of subclinical atherosclerosis in 119 middle-aged healthy men from the general population. METHODS: Erectile function was assessed using the International Index of Erectile Function-5 (IIEF-5). Serum levels of biomarkers of atherosclerosis: Apolipoprotein A, Apolipoprotein B, fibrinogen, and C-reactive protein (CRP) were measured...
October 2016: Current Urology
Gautam Dagur, Kelly Warren, Yimei Miao, Navjot Singh, Yiji Suh, Sardar A Khan
INTRODUCTION: Glomus tumors are benign neoplasms commonly found in subungual regions of the extremities and rarely located in the penis. Misdiagnosis of glomus tumors is common; therefore, symptoms and clinical presentations should be reviewed. OBJECTIVE: The primary objective of this review article is to emphasize the pathogenesis, pathology, clinical presentation, symptoms, diagnosis, and treatment methods of glomus tumors in order to better identify and manage the condition...
October 2016: Current Urology
Mesut Altan, Burak Çıtamak, Hakan Bahadır Haberal, Emrullah Söğütdelen, Ali Cansu Bozaci, Dilek Ertoy Baydar, Hasan Serkan Doğan, Serdar Tekgül
Bladder exstrophy is a complex abnormality and is traditionally treated within the early years of life. It is associated with an increased risk of bladder cancer, with 95% of the arising tumors being adenocarcinomas and 3 to 5% being squamous cell carcinomas. HPV infections are also associated with an increased risk of bladder cancer. This case represents a patient with bladder exstrophy that gave rise to coinciding squamous cell carcinoma and adenocarcinoma. Final pathology results showed an infection with HPV...
May 2016: Current Urology
Matthew Honore, Ross Fowler, Anthony J Kiosoglous
A 24-year-old male was referred to a tertiary hospital for a possible prostatic abscess. The patient went into acute urinary retention. Transurethral drainage was performed. MRI pelvis three days post-operatively identified the prostatic cystic structure as a müllerian duct cyst. Several other phenotypical features were noted on examination as well as findings on investigations. From these diagnosis of hepatocyte nuclear factor-1β (HNF-1β) gene deletion was made.
May 2016: Current Urology
Petar Bajic, Jessica Wetterlin, Larissa Bresler
Urinary tract fungus balls are a rare pathologic entity which may be asymptomatic or have variable presentations. To date, there have been no documented cases of fungus balls presenting as painful bladder syndrome. Painful bladder syndrome is a constellation of symptoms which may include pelvic pain, urgency and frequency not explained by other causes. Here, we present the first case of these two entities concurrently. Our patient had a longstanding history of diabetes, nephrolithiasis and recurrent urinary tract infections...
May 2016: Current Urology
Nikhil Vasdev, Samita Agarwal, Bhavan P Rai, Arany Soosainathan, Gregory Shaw, Sebastian Chang, Venkat Prasad, Gowrie Mohan-S, James M Adshead
INTRODUCTION: Nerve sparing during robotic radical prostatectomy (RRP) considerably improves post-operative potency and urinary continence as long as it does not compromise oncological outcome. Excision of the neurovascular bundle (NVB) is often performed in patients with intermediate and high risk prostate cancer to reduce the risk of positive surgical margin raising the risk of urinary incontinence and impotence. We present the first UK series outcomes of such patients who underwent an intra-operative frozen section (IOFS) analysis of the prostate during RRP allowing nerve sparing...
May 2016: Current Urology
Antonio B Porcaro, Giovanni Novella, Daniele Mattevi, Leonardo Bizzotto, Giovanni Cacciamani, Nicolò De Luyk, Irene Tamanini, Maria A Cerruto, Matteo Brunelli, Walter Artibani
OBJECTIVES: To investigate associations of chronic inflammatory infiltrate (CII) with prostate cancer (PCa) risk and the number of positive cores in patients elected to a first set of biopsies. MATERIALS AND METHODS: Excluding criteria were as follows: active surveillance, prostate specific antigen (PSA) ≥ 30 ng/l, re-biopsies, incidental PCa, less than 14 cores, metastases, or 5-alpha reductase inhibitors. The cohort study was classified as negative (control group) and positive cores between 1 and 2 or > 2...
May 2016: Current Urology
Shohei Tobu, Mitsuru Noguchi, Kohei Takahara, Yuka Ichibagase, Saya Ikoma, Kazuma Udo, Maki Nanri, Jiro Uozumi
INTRODUCTION: In this study, we investigated the effects of treatment with a transurethral incision (TUI) for congenital urethral stenosis, which was accompanied by diurnal and nocturnal enuresis. METHODS: We recruited 21 young males who presented to our department for the treatment of diurnal and nocturnal enuresis from January 2010 to March 2014. All patients underwent TUI due to urethral stricture found by a close investigation. We surveyed each case to evaluate the improvement of diurnal and/or nocturnal enuresis after TUI...
May 2016: Current Urology
Constantinos Tsompos, Constantinos Panoulis, Konstantinos Toutouzas, George Zografos, Apostolos Papalois
OBJECTIVE: The aim of this experimental study was to examine the effect of the antioxidant drug "U-74389G" on a rat model using an ischemia reperfusion protocol. The effect of U-74389G was studied biochemically by measuring mean blood creatinine levels. MATERIALS AND METHODS: Forty rats were used in the study. Creatinine levels were measured at 60 min of reperfusion (groups A and C) or at 120 min of reperfusion (groups B and D), where groups A and B were controls and groups C and D received U-74389G administration...
May 2016: Current Urology
Junya Furukawa, Hideaki Miyake, Taka-Aki Inoue, Takayoshi Ogawa, Hirokazu Tanaka, Masato Fujisawa
BACKGROUND: The objective of this study was to review our experience with radical prostatectomy (RP) as monotherapy for men with high-risk prostate cancer (PCa). PATIENTS AND METHODS: This study included 382 consecutive patients who were diagnosed with high-risk PCa according to the D'Amico definition and subsequently underwent RP without neoadjuvant therapy. Biochemical recurrence (BR) was defined as a serum prostate-specific antigen (PSA) level ≥ 0.2 ng/ml on two consecutive measurements, and none of the patients received any adjuvant therapies until their serum PSA levels reached ≥ 0...
May 2016: Current Urology
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