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Current Urology

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https://www.readbyqxmd.com/read/29234267/incidental-detection-of-occult-thyroid-carcinoma-with-11c-choline-pet-ct-for-high-risk-prostate-cancer
#1
Adama Ouattara, Tiago Ribeiro de Oliveira, Serge Holz, Hannes Van den Bossche, David Strybol, Christophe Assenmacher, Wouter Everaerts, Gert De Meerleer, Steven Joniau
We report a case of a 65-year-old male patient with high-risk prostate cancer, re-staged with 11C-choline positron emission tomography/computed tomography (PET/CT) for prostate specific antigen recurrences 3 years after radical prostatectomy and adjuvant radiation therapy. In addition to 2 suspicious presacral lymph nodes which were resected and proven to be metastatic, PET/CT revealed a very high uptake in a calcified thyroid nodule. Evaluation with fine needle aspiration was suspicious for thyroid carcinoma and the patient underwent total thyroidectomy, confirming a non-metastatic encapsulated follicular variant of papillary thyroid carcinoma...
November 2017: Current Urology
https://www.readbyqxmd.com/read/29234266/glomus-tumor-of-the-scrotum-a-case-report-and-mini-review
#2
Kareim Khalafalla, Abdulla Al-Ansari, Abdelfftah Omran, Hanan Farghaly, Abdulqadir Alobaidy
Glomus tumor in the genital area is extremely rare, with an extensive search in the medical literature revealing only 1 case arising in the scrotum. They can be easily mistaken, both clinically and radiologically, for skin neoplasms or primary testicular tumors involving the scrotum. This report presents a case of a 54-year-old man who presented with a painful right scrotal swelling. Ultrasound suggested the possibility of an epidermal inclusion cyst. The excised mass was diagnosed as a benign glomus tumor...
November 2017: Current Urology
https://www.readbyqxmd.com/read/29234265/the-benefit-of-a-surgical-resection-of-a-solitary-pulmonary-metastasis-of-prostate-cancer-after-radical-prostatectomy
#3
Dries Mortier, Evert Baten, Kurt Vandeurzen, Koenraad van Renterghem
Historically, a solitary pulmonary metastasis of prostate cancer was considered as metastatic or disseminated disease and could only be treated systemically. However, some patients may benefit from surgical metastasectomy of a solitary pulmonary metastasis. We present an uncommon case of resection of a solitary pulmonary metastasis of prostate cancer after previous radical prostatectomy, resulting in un-detectable prostate specific antigen.
November 2017: Current Urology
https://www.readbyqxmd.com/read/29234264/use-of-a-modified-continent-ileovesicostomy-in-adults-with-prior-enterocystoplasty
#4
Juzar Jamnagerwalla, Ali-Reza Sharif-Afshar, Andrew Freedman
Background/Aims: To describe our initial experience with a novel modification of the Mitrofanoff conduit technique utilizing the Yang-Monti ileovesicostomy and the serosa lined extramural tunnel of the T-pouch to create a continent catheterizable stoma in patients with a prior enterocystoplasty. Methods: A 14 cm segment of bowel was harvested, and the distal 4 cm was divided and reconfigured utilizing the Yang-Monti technique. The remaining segment was folded into a U and secured with a serosal basting stitch...
November 2017: Current Urology
https://www.readbyqxmd.com/read/29234263/atypical-small-acinar-proliferation-and-high-grade-prostatic-intraepithelial-neoplasia-should-we-be-concerned-an-observational-cohort-study-with-a-minimum-follow-up-of-3-years
#5
Vinaya Srirangam, Bhavan Prasad Rai, Ahmed Abroaf, Samita Agarwal, Sergey Tadtayev, Charlotte Foley, Tim Lane, Jim Adshead, Nikhil Vasdev
Introduction: Atypical small acinar proliferation (ASAP) and high grade prostatic intraepithelial neoplasia (HGPIN) are considered precancerous. We aimed to measure the rate of repeat biopsy and adenocarcinoma in patients with ASAP and HGPIN and identify any clinico-pathologic parameters at diagnosis of ASAP/HGPIN that are predictive of adenocarcinoma. Materials and Methods: Patients with a diagnosis of ASAP/HGPIN with no previous or concomitant cancer were identified...
November 2017: Current Urology
https://www.readbyqxmd.com/read/29234262/physical-activity-decreases-kidney-cancer-mortality
#6
Michael Liss, Loki Natarajan, Aws Hasan, Jonathan L Noguchi, Martha White, J Kellogg Parsons
Background: To investigate associations of kidney cancer mortality with modifiable risk factors of obesity, physical activity, and smoking. Methods: We evaluate baseline data from US National Health Information Survey from 1998 through 2004 linked to mortality data reporting deaths through 2006. The primary outcome variable was kidney cancer-specific mortality and primary exposure variables were self-reported physical activity and body mass index (BMI). We utilized multivariable adjusted Cox proportional hazards regression models, with delayed entry to account for age at survey interview...
November 2017: Current Urology
https://www.readbyqxmd.com/read/29234261/the-inverse-association-between-the-baseline-renal-function-and-overall-survival-in-patients-with-metastatic-renal-cell-carcinoma-treated-with-molecular-targeted-agents
#7
Hideaki Miyake, Satoshi Imai, Seiichiro Ozono, Masato Fujisawa
Background: The objective of this study was to investigate the prognostic significance of the baseline renal function in metastatic renal cell carcinoma (mRCC) patients treated with molecular-targeted agents. Patients and Methods: This study included 408 consecutive mRCC patients receiving molecular-targeted therapy, consisting of 124 patients in group A and 284 patients in group B who had baseline estimated glomerular filtration rates ≥ 60 ml/min/1.73 m2 and < 60 ml/min/1...
November 2017: Current Urology
https://www.readbyqxmd.com/read/29234260/can-anterior-prostatic-fat-harbor-prostate-cancer-metastasis-a-prospective-cohort-study
#8
Mohannad Hosny, Bhavan Rai, Feras Aljaafari, Samita Agarwal, Thomas McNicholas, Gregory Boustead, Thimothy Lane, James Adshead, Nikhil Vasdev
Objectives: Traditionally anterior prostatic fat (APF) hasn't been included in pelvic lymph node (LN) dissection templates following radical prostatectomy. In this study we evaluate the incidence of lymphoid tissue in the APF and the incidence of LN metastasis in APF in patients who have undergone robotic-assisted laparoscopic radical prostatectomy (RALP). Methods: A prospective database of RALP has been maintained between January 2010 and September 2015. APF is routinely excised and sent separately for histopathological evaluation to identify lymphoid tissue and metastatic prostate cancer...
November 2017: Current Urology
https://www.readbyqxmd.com/read/29234259/simultaneous-measurements-of-follicle-stimulating-hormone-and-total-testosterone-and-associations-in-clinically-localized-prostate-cancer
#9
Antonio B Porcaro, Salvatore Siracusano, Nicolò de Luyk, Paolo Corsi, Marco Sebben, Alessandro Tafuri, Tania Processali, Davide Inverardi, Giovanni Cacciamani, Daniele Mattevi, Maria A Cerruto, Matteo Brunelli, Claudio Ghimenton, Carmelo Monaco, Walter Artibani
Objectives: To evaluate the potential relations of simultaneous measurements of basal levels of follicle stimulating hormone (FSH) and total testosterone (TT) in clinically localized prostate cancer (PCa). Materials and Methods: The study included 126 patients who had simultaneous measurements of prostate specific antigen (PSA), FSH, and TT before undergoing radical prostatectomy for clinically localized PCa. Correlations and independent associations between clinical and pathological factors were investigated by statistical methods...
November 2017: Current Urology
https://www.readbyqxmd.com/read/29234258/toxicity-adverse-events-and-quality-of-life-associated-with-the-treatment-of-metastatic-castration-resistant-prostate-cancer
#10
REVIEW
Senol Tonyali, Hakan Bahadir Haberal, Emrullah Sogutdelen
Objectives: Among males, prostate cancer (PCa) is the most common cancer in Europe and the second most common cancer worldwide, especially in those aged > 70 years. With the advent of novel alternative treatments, survival in patients with advanced PCa has increased. PCa is now considered a chronic disease. Survival is an important endpoint in advanced PCa, as is quality of life (QoL). The effects of the disease and its treatment on patient health-related QoL must be taken into account when selecting the most appropriate treatment options...
November 2017: Current Urology
https://www.readbyqxmd.com/read/28878604/the-effects-of-different-doses-and-patterns-of-docetaxel-chemotherapy-in-japanese-patients-with-castration-resistant-prostate-cancer
#11
EDITORIAL
Tomoyuki Tatenuma, Takashi Kawahara, Yasuhide Miyoshi, Kiyoshi Fujinami, Junichi Ohta, Kazuki Kobayashi, Takeshi Kishida, Masahiro Yao, Hiroji Uemura
No abstract text is available yet for this article.
August 2017: Current Urology
https://www.readbyqxmd.com/read/28878603/abdominal-mass-after-robotic-assisted-laparoscopic-prostatectomy-spigelian-type-trocar-hernia
#12
Seyed Behzad Jazayeri, Johnson F Tsui, David B Samadi
Prostate cancer is the most common cancer in men. Men are diagnosed at early stages of prostate cancer with the use of prostate specific antigen. Surgical removal of the prostate is the standard treatment in localized prostate cancer. Complications after surgical procedures are inevitable. Although robotic prostatectomy has resulted in decreased complications compared to open surgery, complications occur. After an uneventful robotic assisted laparoscopic prostatectomy in a 71-year-old gentleman, with history of chronic cough and continued low dose glucocorticoid use, the patient returned to hospital with complain of a tender abdominal mass in right lower quadrant...
August 2017: Current Urology
https://www.readbyqxmd.com/read/28878602/post-traumatic-isolated-ureteropelvic-junction-avulsion-in-a-child
#13
Tanveer I Dar, Muddasar H Rather, Abdul R Khawaja, Mujahid A Mir, Syed S Nazir
Isolated ureteropelvic junction injuries due to blunt trauma are very rare and are missed at initial presentation in more than 50% patients. Hence they need high index of suspicion for diagnosis which is the main aim of reporting this case.
August 2017: Current Urology
https://www.readbyqxmd.com/read/28878601/an-atypical-presentation-of-retroperitoneal-fibrosis
#14
Wei Phin Tan, Thomas Hwang, Robert Medairos, Dennis A Pessis
A 69-year-old man with a psoriatic arthritis treated with infliximab for 1 month presented to the urology clinic for lower urinary tract symptoms. He was found to have a new diagnosis of elevated creatinine. Computed tomography of the abdomen and pelvis revealed bilateral severe hydronephrosis with abnormal soft tissue thickening of the right renal pelvis and proximal ureter. Bilateral stents were placed after ureteroscopy demonstrated no abnormalities. A computed tomography-guided biopsy of the peri-ureteral lesions revealed fibroadipose tissue with sclerosis and extensive chronic inflammation consistent with retroperitoneal fibrosis...
August 2017: Current Urology
https://www.readbyqxmd.com/read/28878600/kenalog-injection-into-hunner-s-lesions-as-a-treatment-for-interstitial-cystitis-bladder-pain-syndrome
#15
Lauren Rittenberg, Darlene Morrissey, Dominique El-Khawand, Kristene Whitmore
INTRODUCTION: This study aims to evaluate the effectiveness of kenalog injection into Hunner's lesions. MATERIALS AND METHODS: All patients had cystoscopy and bladder hydrodistention with corticosteroid injection into Hunner's lesions over a 2.5-year period. Data include patient characteristics and pre- and post-operative validated questionnaires. Spearman Correlation and Wilcoxon t-tests were used for analysis. RESULTS: One hundred patients were reviewed retrospectively...
August 2017: Current Urology
https://www.readbyqxmd.com/read/28878599/clinical-importance-of-histopathological-inflammation-in-patients-with-lower-urinary-tract-symptoms-due-to-benign-prostatic-hyperplasia-a-prospective-study-of-222-patients
#16
Thibault Meert, Evert Baten, Koenraad van Renterghem
OBJECTIVE: To investigate the relationship between the severity of histopathological prostatic inflammation with lower urinary tract symptoms and prostate specific antigen (PSA) levels. METHODS: We prospectively included 222 consecutive patients eligible for transurethral resection of the prostate in a non-academic referral center by a single surgeon. Patients with proven urinary tract infection or prostate cancer were excluded. Preoperative assessment included PSA levels, International Prostate Symptom Score (IPSS), mean peak flow, mean resected prostate weight and post-residual volume...
August 2017: Current Urology
https://www.readbyqxmd.com/read/28878598/bladder-neck-contracture-following-radical-retropubic-versus-robotic-assisted-laparoscopic-prostatectomy
#17
Benjamin L Spector, Nathan A Brooks, Michael E Strigenz, James A Brown
INTRODUCTION: Radical retropubic prostatectomy (RRP) and robotic-assisted laparoscopic prostatectomy (RALP) are co-standard surgical therapies for localized prostatic adenocarcinoma. These surgical modalities offer similar outcomes; however, lower rate of bladder neck contracture (BNC) is amongst the touted benefits of RALP. The differences between approaches are largely elucidated through multiple-surgeon comparisons, which can be biased by differential experience and practice patterns...
August 2017: Current Urology
https://www.readbyqxmd.com/read/28878597/the-advantages-of-transurethral-resection-of-the-prostate-in-patients-with-an-elevated-or-rising-prostate-specific-antigen-mild-or-moderate-lower-urinary-tract-symptoms-bladder-outlet-obstruction-and-negative-prostate-cancer-imaging-or-prostate-biopsies-a-prospective
#18
Evert Baten, Koenraad van Renterghem
OBJECTIVE: To investigate elevated or rising prostate specific antigen (PSA) as a marker for bladder outlet obstruction (BOO) in patients with minor lower urinary tract symptoms (LUTS) and without prostate cancer. MATERIALS AND METHODS: One hundred and five consecutive patients were prospectively analyzed between 2005 and 2013. All patients were referred to the principal investigator by their general practitioner as a result of an elevated and/or rising PSA. Only patients with minor LUTS [International Prostate Symptom Score (I-PSS) 0-19] and without suspicion for prostate cancer were included...
August 2017: Current Urology
https://www.readbyqxmd.com/read/28878596/nucleotide-transition-390c-t-in-the-wilms-tumor-1-gene-a-risk-factor-of-hypospadias
#19
Gergely Buglyó, Ágnes Magyar, Sándor Biró, István Csízy, Dániel Beyer, Kinga Molnár, Éva Oláh
INTRODUCTION: The gene Wilms' tumor 1 (WT1) encodes a unique transcription factor. Its defects are known to cause a wide range of complex genitourinary malformations and may contribute to non-syndromic forms of hypospadias. MATERIALS AND METHODS: We performed WT1 mutation analysis and copy number analysis of WT1-interacting protein in 13 Hungarian patients diagnosed with isolated hypospadias. RESULTS: Sequencing of WT1 revealed a high frequency of heterozygosity for transition 390C-T (5 heterozygotes out of 13 patients, including 2 brothers)...
August 2017: Current Urology
https://www.readbyqxmd.com/read/28878595/neoadjuvant-platinum-based-chemotherapy-is-an-independent-predictor-for-preoperative-thromboembolic-events-in-bladder-cancer-patients-undergoing-radical-cystectomy
#20
Cliodhna Browne, Niall F Davis, William J Nolan, Eoin D MacCraith, Gerald M Lennon, David W Mulvin, David J Galvin, David M Quinlan
INTRODUCTION: Neoadjuvant chemotherapy (NAC) confers a significant survival benefit in patients with muscle invasive bladder cancer. Platinum-based chemotherapy increases the risk of thromboembolic events (TEE). We determined the effect of cisplatin-based NAC on the incidence of preoperative TEEs in radical cystectomy patients. MATERIALS AND METHODS: A retrospective matched case-control study was performed on 55 patients undergoing radical cystectomy for muscle invasive bladder cancer...
August 2017: Current Urology
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