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Current Urology

Jeremy M West, Andrew J Goates, James A Brown
Intermittent testicular torsion presents with recurrent episodes of severe unilateral testicular pain with resolution of symptoms between episodes. We present a case of a 26-year-old man with a 14-year history of intermittent testicular pain presenting to the urology clinic for elective surgical evaluation. He reported monthly symptoms for many years and had learned to manually reduce the torsion with each episode. Diagnosis of intermittent testicular torsion was made based on patient history and treatment with bilateral orchiopexy resulted in complete symptom resolution and without any loss of testicular function...
March 2018: Current Urology
Vishnu R Mani, Aleksandr Kalabin, Ankita Mishra, Brian Davis-Joseph
We present an incidental finding and management of a urethral diverticulum containing mixed composition of struvite and ammonium urate stones. Status post sleeve gastrectomy, patient presented to our bariatric clinic with epigastric pain associated with nausea and vomiting. A computed tomography scan was performed to rule out any complications of the procedure in which urethral stones were reported contained within a diverticulum. This finding, in retrospect, correlated with patient's past history of recurrent urinary tract infections...
March 2018: Current Urology
Ahmed Adam, Jayveer Sookram
Background: To describe a novel bladder fixation technique for use during endoscopic vesicostomy button insertion. Methods: After standard cystoscopic visualization of the bladder, a standard 18 G intravenous cannula was inserted into the bladder. A non-absorbable suture thread was placed through this intravenous cannula under cystoscopic vision. The proximal end of the suture was then removed using standard ureteroscopic grasping forceps (3 Fr) through another needle (15 G) inserted next to the initial puncture site (following a path at 30 degrees from the initial puncture tract) into the bladder...
March 2018: Current Urology
Rabea A Gadelkareem
Objective: Presentation of our center's experience in the management of intracorporeally-retained urological surgical items. Materials and Methods: Retrospective search of our center's data for cases of retained surgical items during the period July 2006 to June 2016. Each case was studied for the demographic and clinical variables including types, presentation, and management. Results: Out of more than 55,000 different urological interventions, only 39 cases (28 males and 11 females) had retained surgical items...
March 2018: Current Urology
Denglu Zhang, Kailin Li, Chao Sun, Guangshang Cao, Yuanfu Qi, Zhaomin Lin, Yanxia Guo, Zhiyong Liu, Yuan Chen, Jiaxin Liu, Guanghui Cheng, Peng Wang, Lu Zhang, Jianye Zhang, Jiliang Wen, Dawei Xu, Feng Kong, Shengtian Zhao
Objective: To evaluate the potential anti-prostate cancer effects of Paris polyphylla ethanol extract (PPEE) and its underlying mechanisms. Materials and Methods: The anti-proliferation activity of PPEE was tested on PC3 and DU145 cells using Cell Counting Kit-8 assay. The pro-apoptotic and cell cycle arrest effects of PPEE were confirmed by flow cytometry. Apoptosis of prostate cancer cells was induced by PPEE through endogenous and exogenous pathways. A mouse xenograft model was used to examine its anti-prostate cancer effects in vivo ...
March 2018: Current Urology
Geoffrey S Gaunay, Robert G Berkenblit, Christian H Tabib, Jeffrey R Blitstein, Manoj Patel, David M Hoenig
Objective: To expand the diagnostic armamentarium for medullary sponge kidney (MSK), we evaluate the use of high-resolution multidetector computed tomography (MDCT) for MSK diagnosis and compare to the standard intravenous urography (IVU). Despite a significant prevalence amongst stone formers, diagnosis of this well described condition has declined. IVU, the gold standard in MSK diagnosis, has largely been replaced by CT, which has previously been shown unable to demonstrate signs of MSK...
March 2018: Current Urology
Yanxia Guo, Zhiyong Liu, Kailin Li, Guangshang Cao, Chao Sun, Guanghui Cheng, Denglu Zhang, Wei Peng, Jiaxin Liu, Yuanfu Qi, Lu Zhang, Peng Wang, Yuan Chen, Zhaomin Lin, Yong Guan, Jianye Zhang, Jiliang Wen, Fang Wang, Feng Kong, Dawei Xu, Shengtian Zhao
Objectives: Paris polyphylla var. yunnanensis (PPVY), a Chinese herb, has long been used for cancer treatment, and its steroidal saponins are suggested to exert an anti-tumor activity, however, the underlying mechanism is incompletely understood and their effect on bladder cancer (BC) remains unknown. The present study is thus designed to address these issues. Material and Methods: Total steroidal saponins were extracted with ethanol from PPVY and used to treat BC cells (HT1197 and J82 carrying mutant p53)...
March 2018: Current Urology
Victor G Ilie, Vlad I Ilie
Background: The aim of the study is to comprehensively report on a single tertiary referral center experience with the use of ureteric stents, assess complication burden and determine risk factors to further inform institutional practice. Materials and Methods: The retrospectively analyzed cohorts includes 529 patients treated over a 12 months period. Data regarding details of the index pathology, stent characteristics and complications were collected retrospectively...
March 2018: Current Urology
Elad Leron, Adi Y Weintraub, Salvatore A Mastrolia, Polina Schwarzman
Overactive bladder (OAB) syndrome is a chronic medical condition which has a major influence on the quality of life in a significant amount of the population. OAB affects performance of daily activities and has an estimated prevalence of 16.5%. Many sufferers do not seek medical help. Moreover, many family physicians and even gynecologists are not familiar with this issue. Usually patients suffer from OAB in advanced age. Nocturia is reported as the most bothersome symptom in the elderly population. The aim of our review was to discuss all aspects of this challenging disorder and suggest tools for assessment and management strategies...
March 2018: Current Urology
Senol Tonyali, Ahmet M Aydin
Objective: To investigate the clinical consequences of neglected risk of urolithiasis in deceased kidney donors in routine clinical practice, this study focused on different management options for transplanted allograft stones, and tried to find new solutions for more accurate detection of urolithiasis in deceased kidney donors prior to renal transplantation. Methods and Results: The overall prevalence of stone disease in endemic countries is between 7 and 29%. Because of the increased risk for stone disease in epidemic countries, screening renal grafts from deceased donors necessitates more sensitive imaging tests...
March 2018: Current Urology
Umar Karaman, Faye B Serkin, Jennifer M Taylor, Michael Constantinescu
Testicular yolk sac tumor (YST) is a nonseminomatous germ cell tumor that predominantly affects prepubescent boys. Pure endometrioid variant YST is rare, with only 1 report in the literature. We present the first reported case of en-dometrioid variant YST with mature teratoma in the retro-peritoneal specimen.
February 2018: Current Urology
Priyanka Rai, Alok Srivastava, Ishwar R Dhayal, Sanjeet Singh
Objectives: To compare bipolar vaporization of prostate (BPVP) with photoselective vaporization (PVP) of prostate in the surgical management of benign prostatic hyperplasia in terms of safety, efficacy and cost effectiveness. Methods: Data was analyzed retrospectively for patients who underwent either PVP or BPVP between August 2012 to July 2014 for prostate size ≤ 80 ml. Preoperative and postoperative period values along with details like operative time, blood loss, hospitalization days, catheter removal time, blood transfusion and etc...
February 2018: Current Urology
Charles J Paul, Nathan A Brooks, George M Ghareeb, Chad R Tracy
Background/Aims: Many providers elect to place a stent following ureteroscopy for nephrolithiasis, but little data exists on the optimal duration to leave a stent. We sought to determine whether there are any differences in post-operative outcomes for patients with a 3 versus 7-day stent following ureteroscopy. Methods: We retrospectively reviewed 247 patients who underwent unilateral ureteroscopy with lithotripsy, 79 of whom removed a stent with an extraction string at 3 or 7 days post-operatively...
February 2018: Current Urology
Javanmard Babak, Fadavi Behruz, Yousefi Mohammadreza, Fallah-Karkan Morteza
Introduction: To study the stimulating effect of human chorionic gonadotropin (hCG) on spermatogenesis in patients with varicocele and infertility undergoing varicocelectomy. Materials and Methods: In the study, 188 infertile patients with varicocele were included. Open inguinal varicocelectomy was performed. They were randomized into 2 groups and hCG (91 patients) was administered intramuscularly by dosage of 5,000 international units every week for 3 months. A semen analysis was obtained at 6 months, post-operatively and cases were followed for 2 years for pregnancy report...
February 2018: Current Urology
Antonio B Porcaro, Daniele Mattevi, Giovanni Novella, Nicolò De Luyk, Paolo Corsi, Leonardo Bizzotto, Davide De Marchi, Marco Sebben, Alessandro Tafuri, Davide Inverardi, Tania Processali, Maria A Cerruto, Matteo Brunelli, Salvatore Siracusano, Walter Artibani
Objectives: To investigate associations of the transitional zone volume (TZV) with intraprostatic chronic inflammatory infiltrate (CII) and prostate cancer (PCa) risk in patients undergoing a first random biopsy set. Materials and Methods: The study included a homogenous population of 596 patients. The volume of the prostate and TZV were separately measured. Independent associations were investigated by multivariate logistic regression analysis. Results: The median TZV was 18 ml, CII was detected in 157 cases (26...
February 2018: Current Urology
Aditya K Singh, Pushpendra K Shukla, Sartaj W Khan, Vazir S Rathee, Udai Shankar Dwivedi, Sameer Trivedi
Purpose: A modified Clavien classification system has been proposed to grade perioperative complications. We share our experience in grading the complications of percutaneous nephrolithotomy (PNL), according to this new classification. Methods: A total of 809 PNLs performed between 2010 and 2014 were reviewed retrospectively. The modified Clavien classification system, which classifies the perioperative complications into 5 grades, was applied. Grade wise comparison of complications between the patients with simple and complex calculi was done...
February 2018: Current Urology
Rabea A Gadelkareem
Introduction: Surgical never events are preventable harmful non-intentional human errors. Urology is a common surgical specialty for their occurrence. Patients and Methods: A retrospective search of our center's data was done during the period 2006-2016 for surgical never events. Each included case was studied for the primary diagnosis, procedure, and subspecialty, never event type and timing, needed extra-interventions, urologist/procedure proportioning, outcomes, and possible underlying causes of the event...
February 2018: Current Urology
Brian M Inouye, Francis M Hughes, Stephanie J Sexton, J Todd Purves
Irritative voiding symptoms (e.g. increased frequency and urgency) occur in many common pathologic conditions such as urinary tract infections and bladder outlet obstruction, and these conditions are well-established to have underlying inflammation that directly triggers these symptoms. However, it remains unclear as to how such diverse stimuli individually generate a common inflammatory process. Jürg Tschopp provided substantial insight into this conundrum when, working with extracts from THP-1 cells, he reported the existence of the inflammasome...
February 2018: Current Urology
Philip Alexandrov, Wei Phin Tan, Lev Elterman
Dermatillomania is a rare disease that seldom affects the genitals. Genital dermatillomania has not yet been recognized as a separate entity within the disease. The purpose of the report is to highlight a new facet of dermatillomania and inform urologists that dermatillomania could be a potential reason for genital ulcers. This report documents 2 cases of genital dermatillomania which vary in severity from mild (case 1), where the patient's ulcers healed after extensive counseling, to extremely dire (case 2), where the patient lost his penis after recurring ulcers and multiple reconstructive surgeries...
November 2017: Current Urology
Ayse V Dikmen, Cagri Guneri, Serdar Yalcin, Onur Acikgoz, Esat Ak, Sadettin Cetiner
A 74-year-old male patient with prostate cancer under remission was admitted with left inguinoscrotal swelling. He underwent scrotal ultrasound demonstrating a giant in-guinoscrotal hernia. Contrast-enhanced computerized tomography of the abdomen and pelvis demonstrated a left pelvic kidney associated with severe hydroureteronephrosis secondary to a ureteral inguinoscrotal hernia. Upon exploration with left inguinal incision, a paraperitoneal ureteral in-guinoscrotal hernia and a hypertrophic left spermatic cord were observed...
November 2017: Current Urology
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