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Iranian Journal of Child Neurology

Sedigheh Rafiei Tabatabei, Roxana Azma, Manijeh Kahbazi, Abdonaser Farzan, Maryam Kazemi Aghdam, Kimia Seifi, Negin Nahanmoghaddam
Gram-negative meningitis can occurssubsequent to dura-arachnoid barrier disruption because of trauma, surgery and rarely an infected dermoid cyst. Association of neurosurgical procedures with Gram-negative meningitis was described for the first time in 1940. Intracranial infections from gram-negative bacilli like Enterobacter are serious and difficult to treat as many antibiotics fail to achieve bactericidal concentrations in the cerebrospinal fluid. Here in, we report a rare case of pediatric Enterobacter meningitis in a patient with a dermoid cyst that had been manipulated...
2018: Iranian Journal of Child Neurology
Amiereza Vafaee, Taghi Baghdadi, Sara Norouzzadeh
A 7-yr-old patient was referred to pediatric orthopedic clinic of Imam hospital (2016) with the diagnosis of cerebral palsy (CP). His parents were concerned about some inconsistency of his disease progression. After initial evaluations, the diagnosis of CP was incorrect. The true diagnosis was suspected and confirmed with molecular genetic analysis. A rare autosomal recessive disorder -Cockayne syndrome- was diagnosed. Although untreatable, it can be prevented by appropriate prenatal diagnostic tests for their future children...
2018: Iranian Journal of Child Neurology
Zarrin Keihanidost, Aydin Tabrizi, Elahe Amini, Mojtaba Sedaghat, AmirAli Ghahremani, Mamak Shariat, Zeinab Kavyani
Objectives: Hearing loss is one of the most important disabilities in neonates. Delay in the detection of hearing loss leads to impaired development and may prevent the acquisition of speech. We aimed to determine the risk factors associated with hearing loss in neonatal patients aged more than 6 months with a history of hospitalization in Neonatal Intensive Care Unit (NICU). Methods: In this case-control study, screening for hearing loss was carried out on 325 neonates aged 6-12 months referred to Pediatric Neurology Office of Vali-e-Asr Hospital, Tehran, Iran up to 2011...
2018: Iranian Journal of Child Neurology
Sousan Salehi, Ahmad Reza Khatoonabadi, Mahmoud Reza Ashrafi, Ghasem Mohammadkhani, Saman Maroufizadeh, Fatemeh Majdinasab
Objectives: Emotion is a key component in language processing, but emotional words processing in children is still controversial. We aimed to investigate the relationship between emotional dimensions, arousal and valence, word familiarity, comprehension, use, and emotional content recognition. Eventually, a list of emotional content words for this age was prepared in Persian. Materials&Methods: The study was conducted in selected elementary schools in Tehran, Iran from April to June 2017...
2018: Iranian Journal of Child Neurology
Zahra Babaei, Talieh Zarifian, Atieh Ashtari, Enayatollah Bakhshi, Mona Ebrahimpour
Objectives: Human beings can use gestures such as pointing and reaching to communicate with others before they have the ability to use verbal communication to produce speech. Given the importance of children's communication development and the key role of gestures development in communicating, the main purpose of this study was to analyze the normal development of pointing and reaching gestures and their relationship in 12-16-month-old children speaking Farsi. Materials & Methods: In this prospective, observational and longitudinal study the gestures of 11 monolingual Farsi-speaking children (7 boys and 4 girls, from Oct 2015 to Jan 2017 in the homes of participants across Tehran, Iran) were evaluated via non-randomized sampling method...
2018: Iranian Journal of Child Neurology
Abolfazl Mahyar, Parviz Ayazi, Elaheh Azimi, Reza Dalirani, Ameneh Barikani, Shiva Esmaeily
Objectives: Febrile seizure is the most common type of seizure among children. Identification of factors involved in febrile seizure is highly critical. The present study was conducted to determine the association between children's urinary tract infection and febrile seizure. Materials & Methods: In this case-control study, 165 children with simple febrile seizure (case group) were compared with 165 children with fever and without seizure (control group) in terms of urinary tract infection (UTI) in Qazvin, central Iran in 2015-2016...
2018: Iranian Journal of Child Neurology
Kolsoum Saeidi, Nasrollah Saleh Gohari, Seyed Ebrahim Mansouri Nejad
Objectives: Ataxia telangiectasia (AT) is a rare autosomal recessive disorder caused by mutation in the Ataxia telangiectasia mutated (ATM) gene. This disorder is characterized by progressive cerebellar ataxia, telangiectasia, immunodeficiency and a predisposition to leukemia/lymphoma. In this study, we investigated a family with a new mutation in ATM, confirmed by molecular genetic test. Materials&Methods: Four members of a family including a symptomatic AT patient, his parents and sibling were examined for ATM gene defects at Kerman University Hospital, Kerman, Iran in 2016...
2018: Iranian Journal of Child Neurology
Mohsen Mollamohammadi, Zeinab Sadat Amirhoseini, Alireza Saadati, Zahra Pirzadeh, Masoud Hassan Amouzadeh
Objective: Seizure is the most common signs of nervous system disease in neonates. The first line of treatments in neonatal seizures (after ruling out and emergency treatment of electrolyte imbalance and hypoglycemia) are phenobarbital and phenytoin. We aimed to evaluate drugs that are more effective on neonatal seizure. Materials & Methods: Patients admitted to neonatal wards & NICUs (level   IIa&  IIb) in Qom hospitals (2015-2017), central Iran with presentation of seizure, were enrolled in this clinical trial study...
2018: Iranian Journal of Child Neurology
Nasrin Baraheni, Seifollah Heidarabady, Shahrooz Nemati, Morteza Ghojazadeh
Objective: The main aim of the current research was evaluation of concurrent validity of the Goodenough-Harris Draw-A-Man Test (GHDAMT) with the problem-solving subscale of ASQ2 among children between 54-60 months old in Tabriz City, northwestern Iran. Materials & Methods: In this cross-sectional study, 136 males and 105 females were selected by simple random sampling from nursery schools in Tabriz City, northwestern Iran in 2014 and tested with GHDAMT and ASQ2 to compare the concurrent validity of these tests in evaluation of cognition...
2018: Iranian Journal of Child Neurology
Ali Khajeh, Fariba Yaghoubinia, Saeedeh Yaghoubi, Afshin Fayyazi, Ghasem Miri Aliabad
Objectives: Acute prolonged seizure is the most common neurological emergency in children. This research was conducted to compare the effect of intravenous phenobarbital and Sodium valproate in control of seizure in children with status epilepticus, referred to emergency ward from Mar to Nov 2013. Materials & Methods: In this randomized clinical trial, registered with the code number IRCT2015051722300N1, 80 children aged 6 months to 10 years with prolonged seizure and with no response to one dose of diazepam (0...
2018: Iranian Journal of Child Neurology
Zahra Nobakht, Mehdi Rassafiani, Seyed Ali Hosseini
Objectives: Caregivers of children with cerebral palsy (CP) have to spend a long time to take care of their children. We aimed to develop a user-friendly web-based intervention for training parents of children with CP and evaluate the process of development using modified CeHRes roadmap. Materials & Methods: The study was conducted from September 2016 to September 2017 in Tehran, Iran. We did it in four main steps including determining the needs of users, content development, design, operational development and evaluation...
2018: Iranian Journal of Child Neurology
Zahra Khodagholi, Talieh Zarifian, Farin Soleimani, Maryam Khoshnood Shariati, Enayatollah Bakhshi
Objectives: Given the positive effects of stimulation with breast milk odor and non-nutritive sucking (NNS) on preterm feeding skills, we examined the effect of NNS and milk odor, on the time of achieving independent oral feeding in preterm infants. Materials & Methods: This study was conducted at two Neonatal Intensive Care Units of Tehran, Iran in 2016. Overall, 32 neonates with gestational ages of 28-32 wk were enrolled in two groups; NNS with and without olfactory stimuli (breast milk odor)...
2018: Iranian Journal of Child Neurology
Fatemeh Cheraghi, Farshid Shamsaei, Afshin Fayyazi, Fahimeh Molaaei Yeganeh, Godratolah Roshanaei
Objectives: Headache and sleep problems are commonly reported in children, and both can adversely impact the child's life. We aimed to compare the sleep quality and intensity of headache between school-age children with migraine as well as tension headache and healthy children. Materials & Methods: In this cross-sectional study, 198 children 6-12 yr old in three groups were enrolled from Aug 2015 to Mar 2016. Migraine and tension headache groups from the Outpatient Clinic of Imam Khomeini of Hamadan, western Iran and healthy group from elementary schools were randomly selected (66 children in each group)...
2018: Iranian Journal of Child Neurology
Asmika Asmika, Lirista Dyah Ayu Oktafiani, Kusworini Kusworini, Hidayat Sujuti, Sri Andarini
Objective: This research was an experimental study that was aimed to detect differences response of tactile sensory stimulus between normal children and children with sensory brain development disorders such as Autism Spectrum Disorder (ASD). Materials & Methods: A total of 134 children, in two groups including 67 healthy children (control) and 67 children with autism were studied. Tactile sensory stimulus responses in children were tested directly using a Reflex Hammer...
2018: Iranian Journal of Child Neurology
Razieh Fallah, Shiva Eiliaei, Farzad Ferdosian
Objectives: We aimed to answer the question whether or not previous antiepileptic drugs with combination of omega-3 and risperidone are more efficient than previous antiepileptic drugs with risperidone alone in decreasing of seizures monthly frequency of children with refractory epilepsy and attention-deficit/hyperactivity disorder (ADHD). Material & Methods: In a randomized clinical trial (IRCT201604212639N18), participants referred to Pediatric Neurology Clinic of Shahid Sadoughi Hospital, Yazd, Iran from Jun 2015 were distributed randomly into two groups...
2018: Iranian Journal of Child Neurology
Ali Reza Jamali, Malek Amini
Objectives: Constraint-Induced Movement Therapy (CIMT) is an intervention method that can enhance cerebral palsy (CP) children's hand function. CP is a pervasive and common disorder which affects many aspects of a child life. Hemiplegic CP affects one side of a child's hand and has great effect on child's independence. We investigated the CIMT's studies conducted in Iran, and indicated the effectiveness of CIMT on duration and children age? Materials & Methods: This systematic review was conducted using the electronic databases such as Medline PubMed, CINAHL, etc...
2018: Iranian Journal of Child Neurology
Nahid Khosroshahi, Ali Nikkhah
Macrocephaly is one of the most frequent reasons for referral to a pediatric neurologist. Benign enlargement of subarachnoid space (BESS) in infancy is the most common cause of macrocephaly and characterized clinically with large head circumference, normal or mildly motor and language delay and increased cerebrospinal fluid (CSF) in the subarachnoid space with normal ventricles or mild ventriculomegaly. In this review, we describe the etiology, epidemiology, clinical presentation, pathogenesis, neuroimaging, differential diagnosis, treatment and outcome of this entity from current literature with emphasis on diagnostic work-up...
2018: Iranian Journal of Child Neurology
Liqin Zhu, Huayu Wang
No abstract text is available yet for this article.
2018: Iranian Journal of Child Neurology
Ivan Baltadzhiev, Ina Geneva, Nedialka Popivanova
Guillain-Barré syndrome (GBS) belongs to the group of peripheral immune-mediated neuropathies often preceded by an inflammatory episode. GBS is rarely associated with hepatitis A virus (HAV) infection, the latter as a rule antecedent of the neurological disorders. This association is quite rare in childhood, and so far, only isolated cases have been described. We report an unusual case of pediatric GBS which development coincided with the development of HAV IgM (+) viral hepatitis A. From the second to the 14th day after admission to the hospital for mild jaundice of the skin and sclera in a 12-yr-old boy, the following neurological disorders have developed: absent Achilles and knee-jerk reflexes, diminished brachioradialis reflex, moderately decreased muscle power in the upper extremities and more pronounced power loss in the lower extremities...
2018: Iranian Journal of Child Neurology
Amir Hossein Babaei, Soroor Inaloo, Mitra Basiratnia, Ali Derakhshan
Schimke Immuno-osseous Dysplasia (SIOD) is a rare autosomal recessive disease caused by a biallelic mutation in SMARCAL1 gene. Typical findings in SIOD include spondylo-epiphyseal dysplasia, steroid resistance nephrotic syndrome, progressive renal failure, T-cell immunodeficiency, bone marrow failure, and cerebral infarction. In this case report, we describe a 9-yr-old girl who presented with failure to thrive in infancy. Nephrotic syndrome was diagnosed at the age of four years. She had three episodes of admission with cerebral stroke due to moyamoya syndrome...
2018: Iranian Journal of Child Neurology
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