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Iranian Journal of Child Neurology

Liqin Zhu, Huayu Wang
No abstract text is available yet for this article.
2018: Iranian Journal of Child Neurology
Ivan Baltadzhiev, Ina Geneva, Nedialka Popivanova
Guillain-Barré syndrome (GBS) belongs to the group of peripheral immune-mediated neuropathies often preceded by an inflammatory episode. GBS is rarely associated with hepatitis A virus (HAV) infection, the latter as a rule antecedent of the neurological disorders. This association is quite rare in childhood, and so far, only isolated cases have been described. We report an unusual case of pediatric GBS which development coincided with the development of HAV IgM (+) viral hepatitis A. From the second to the 14th day after admission to the hospital for mild jaundice of the skin and sclera in a 12-yr-old boy, the following neurological disorders have developed: absent Achilles and knee-jerk reflexes, diminished brachioradialis reflex, moderately decreased muscle power in the upper extremities and more pronounced power loss in the lower extremities...
2018: Iranian Journal of Child Neurology
Amir Hossein Babaei, Soroor Inaloo, Mitra Basiratnia, Ali Derakhshan
Schimke Immuno-osseous Dysplasia (SIOD) is a rare autosomal recessive disease caused by a biallelic mutation in SMARCAL1 gene. Typical findings in SIOD include spondylo-epiphyseal dysplasia, steroid resistance nephrotic syndrome, progressive renal failure, T-cell immunodeficiency, bone marrow failure, and cerebral infarction. In this case report, we describe a 9-yr-old girl who presented with failure to thrive in infancy. Nephrotic syndrome was diagnosed at the age of four years. She had three episodes of admission with cerebral stroke due to moyamoya syndrome...
2018: Iranian Journal of Child Neurology
Ali Khajeh, Ghasem Miri Aliabad, Afshin Fayyazi, Gholamreza Soleimani, Reza Keikha
When a child presents with cranial nerve palsy and a bulging fontanel, a pediatric neurologist is often consulted to determine the cause of increased intracranial pressure. This report describes an infant with chronic myelogenous leukemia (CML) referred to Ali-bin-Abitaleb Hospital, Zahedan, eastern Iran in 2013 who presented with seventh cranial nerve palsy and bulging fontanel. Chromosomal analysis and peripheral blood smear confirmed the diagnosis of CML.
2018: Iranian Journal of Child Neurology
Rahim Vakili, Somayyeh Hashemian
Beta-ketothiolase deficiency is a rare autosomal recessive disorder characterized by an inborn error of isoleucine catabolism and affecting ketone body metabolism. Clinical features characterized by intermittent keto acidotic episodes are associated with clinical signs and symptoms of toxic encephalopathy such as lethargy, hypotonia, vomiting, tachypnea, and coma in some patients, with an onset during infancy or toddler-hood. A two months old girl presented to pediatric ward of Imam Reza Hospital in Mashhad City, Northwestern Iran in October 2016, with acute episode of fever and toxic encephalopathy with attack of vomiting, hypotonia, lethargy, tonic-clonic seizures and then a day in coma, few days after vaccination...
2018: Iranian Journal of Child Neurology
Ghazal Zahed, Marjan Shakiba, Kimia Seifi
Objective: As there were a few studies on the mental disorders resulting from diabetes in children, this study aimed at investigating the prevalence of psychological disorders among children. Materials & Methods: We enrolled 323 children with diabetes type 1 aged 5-12 yr old referring to Endocrinology Clinic of Mofid Hospital, Tehran, Iran in 2014-2015. In addition, 317 healthy children were considered as control group. The materials used for data analysis were information form and questionnaire CSI-4 filled out by their parents...
2018: Iranian Journal of Child Neurology
Mohammad Ghofrani, Mohammad Mehdi Nasehi, Sasan Saket, Mohsen Mollamohammadi, Mohammad Mahdi Taghdiri, Parvaneh Karimzadeh, Seyed Hassan Tonekaboni, Mohsen Javadzadeh, Narjes Jafari, Azadeh Zavehzad, Masoud Hasanvand Amouzadeh, Mahsa Beshrat, Meysam Babaei
Objective: This study was conducted to predict the response to treatment in patients treated with anti-epilepsy drugs. Material and Methods: This analytical questionnaire-based study was conducted in 2014 among 128 patients with epilepsy admitted to Mofid Children's Hospital, Tehran, Iran. The inclusion criteria were children 2 months to 12 yr of age with epilepsy and patients who experienced fever and seizure attacks at least once were excluded from the study. Patients were followed up for 6 months and the response to their treatment was recorded...
2018: Iranian Journal of Child Neurology
Fahimeh Soheilipoor, Azita Tavasoli, Zeinab Babasafari Renani
Objectives: Febrile seizure is the most common seizure disorder in childhood. Anemia or failure to thrive can predispose children to febrile seizure by affecting the nervous system function. The current study investigated the association between febrile seizures and anemia or failure to thrive. Materials and Methods: This case-control study was performed on 307 children 6 months to 6 yr old age hospitalized at the Ali Asghar Children`s Hospital, Tehran, Iran from 2011 to 2014 divided into two groups as follows: A case group including 158 children with febrile seizures and a control group including 149 febrile children without seizure...
2018: Iranian Journal of Child Neurology
Abdulrasool AlAEE, Ali Abbaskhanian, Maedeh Azimi, Mohammadreza Azimi
Objective: Migraine is a common headache associated with structural changes in brain. The purpose of this study was to evaluate brain MRI findings in children with migraine. Materials & Methods: This cross-sectional study was conducted at Booali Hospital, Mazandaran University of Medical Sciences, Sari, Iran. Participants with headache and age between 5 and 15 yr were evaluated with MRI and their headache type was diagnosed by the standard criteria. The findings of the MRI were interpreted by a radiologist blinded to the diagnoses...
2018: Iranian Journal of Child Neurology
Afshin Fayyazi, Ali Khajeh, Ashraf Baghbani
Objective: Febrile seizures are the most common type of convulsions. Medicinal prophylaxis is sometimes used for children at high risk of recurrent febrile seizure. In certain circumstances, conventional drugs such as diazepam and phenobarbital cannot be used and the need for alternative medicines is felt. This study compared the effectiveness of topiramate and diazepam in preventing the risk of recurrent febrile seizure in children under 2 yr old. Materials and Methods: This randomized controlled trial, in Besat Hospital in Hamedan, Iran from 22 Nov 2013 to 22 Nov 2015 (Registered code: IRCT Number: IRCT2015010120527N1), included 54 patients, at risk of recurrent febrile seizure, inhibited from taking phenobarbital...
2018: Iranian Journal of Child Neurology
Hamid Nemati, Parvaneh Karimzadeh, Minoo Fallahi
Objective: Neonatal seizures are common, difficult to diagnose and treat, and associated with a great mortality rate and long-term risk of neurodevelopmental impairments. We aimed to determine the etiology, clinical presentation, and neurodevelopmental outcome of neonatal seizures. Materials and Methods: In this cross-sectional study, 88 neonates, aged < 28 days, admitted to Mofid Children's Hospital, Tehran, Iran, from September 2011 to 2013 with the initial diagnosis of seizure were enrolled by convenient sampling method...
2018: Iranian Journal of Child Neurology
Parvin Raji, Afsoon Hassani Mehraban, Faranak Aliabadi, Maryam Ahmadi, Veronica Schiariti
Objectives: Comprehensive ICF Core Set of cerebral palsy (CP) includes a set of functions of children with CP has been created recently. This study determined the content validity of this version based on Iranian Occupational Therapists' perspectives to explore whether the ICF Core Sets for CP include the areas of function of CP in Occupational Therapy practice. Materials & Methods: This qualitative study conducted from Feb 2015 to Apr 2016 in Tehran, Iran. Experts were the academic staffs selected through convenience sampling...
2018: Iranian Journal of Child Neurology
Hossein Zeraati, Fatemeh Nasimi, Akram Rezaeian, Javad Shahinfar, Maryam Ghorban Zade
Objectives: Preterm birth is considered as a risk factor for developmental disabilities, which can lead to long-term effects on the nervous system of children. The aim of this study was to determine the effect of multi-sensory stimulation on neurodevelopment of premature infants. Materials and Methods: In this two-group double-blind clinical trial in Jahrom Hospital, Jahrom, Iran from Jun to Aug 2016, 80 preterm infants were randomly divided. The intervention group received multisensory stimulation for 12 min per session, 5 sessions per wk along with routine NICU care and the control group received ward's routine care...
2018: Iranian Journal of Child Neurology
Mahmoud Reza Ashrafi, Reza Azizi Malamiri, Sedigheh Shams, Neda Rashidi Ranjbar, Sara Ebrahimi Nasrabadi, Mohammadtaghi Haghi Ashtiani, Nargess Saladjegheh, Varasteh Vakili Zarch
Objectives: This case-control study was carried out to compare serum total antioxidant capacity (TAC) in the newly diagnosed children with epilepsy and that of a control group of healthy children at the same age and probable effects of antiepileptic drugs (AEDs) prescription on it. Materials & Methods: Overall, 130 participants (65 in each group) aged between 1 and 17 yr old were enrolled. The study was conducted in Children's Medical Center, the Pediatrics Center of Excellence, Tehran, Iran in 2010...
2018: Iranian Journal of Child Neurology
Zahra Chavoshzadeh, Amir Hashemitari, Sepideh Darougar
Objective: Primary immunodeficiencies (PID) are a heterogeneous group of disorders with a variable clinical spectrum of manifestations. The central nervous system may be involved in PID with symptoms which may present initially or develop at later stages. The purpose of this study was to review the neurological manifestations of different PID syndromes. Materials & Methods: We focused on 104 selected studies on PID with certain neurological abnormalities which may accompany these disorders or may later signify a PID in their course...
2018: Iranian Journal of Child Neurology
Marzieh Parhoudeh, Soroor Inaloo, Mozhgan Zahmatkeshan, Zahra Seratishirazi, Saeedeh Haghbin
Objective: We aimed to investigate the blood lead level (BLL) in children with neurologic disorders of unknown causes and compare with normal children. Materials & Methods: In this prospective case-control study, 68 patients aged 1 to 18 yr with neurologic disorders of unknown causes, were referred to pediatric neurology clinics and wards, Shiraz, Iran selected during a 12 months period from Sep 2013. They were compared with 1:1 ratio, age, and sex-matched healthy children...
2018: Iranian Journal of Child Neurology
Azadeh Ghaheri, Saman Maroufizadeh
No abstract text is available yet for this article.
2018: Iranian Journal of Child Neurology
Afagh Assanzadehrad, Vahid Aminzadeh
Gait disturbance is a common presentation of neurologic disease in children. Limping is a kind of gait dysfunction that occurs due to neurologic & skeletal diseases. Diskitis is an inflammatory process noted as one of the significant causes of limping especially in children aged less than 3 yr. Here we report case of diskitis and limping as the significant manifestation of Gait disturbance in A 22 months old boy from 17 Shahrivar Hospital in 2016, Rasht, northern Iran. Regarding normal neurologic exam, nervous system involvement was less possible...
2018: Iranian Journal of Child Neurology
Mehran Beiraghi Toosi, Javad Akhondian, Farah Ashraf Zadeh, Nahid Donyadideh, Asma Javid
Wilson's disease (WD) is a rare autosomal recessive disease due to copper metabolism disturbance. The clinical presentation spectrum of Wilson's disease is wide and initial findings of the disease depend on the organ involved. Neurologic disorders can develop insidiously or precipitously with intention tremor, dysarthria, rigid dystonia, Parkinsonism, deterioration in school performance or behavioral changes. This article is presenting an 11-yr old boy with chief complaint of falling and upper limb spasm. He referred to the Neurology Department, Ghaem Hospital, Mashhad, northeastern Iran in 2016...
2018: Iranian Journal of Child Neurology
Sangeetha Yoganathan, SniyaVALSA Sudhakar, Maya Thomas, Atanu Kumar Dutta, Sumita Danda, Mahalakshmi Chandran
Molybdenum cofactor deficiency is a rare metabolic disorder manifesting with early onset seizures, developmental delay, microcephaly, and spasticity. In this report, we describe a three-month-old infant with neonatal onset, poorly controlled seizures, developmental delay, microcephaly, spastic quadriparesis and visual insufficiency. Magnetic resonance imaging of brain had shown cystic encephalomalacia involving bilateral parieto-occipital lobe and elevated lactate in magnetic resonance spectroscopy. Restricted diffusion noted along the corticospinal tract in our case is a novel imaging finding in patients with molybdenum cofactor deficiency...
2018: Iranian Journal of Child Neurology
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