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Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology

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https://www.readbyqxmd.com/read/28294102/fms-like-tyrosine-kinase-3-flt3-and-nucleophosmin-1-npm1-in-iranian-adult-acute-myeloid-leukemia-aml-patients-with-normal-karyotype-mutation-status-and-clinical-and-laboratory-characteristics
#1
Narges Rezaei, Nargess Arandi, Behnaz Valibeigi, Sezaneh Haghpanah, Mehdi Khansalar, Mani Ramzi
No abstract text is available yet for this article.
March 15, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28294101/screening-of-intron-1-inversion-of-factor-viii-gene-in-130-patients-with-severe-haemophilia-a-from-pakistani-cohort
#2
Azhar Sattar, Shabbir Hussain, Muhammad Ikram Ullah, Saqib Mahmood, Shahida Mohsin
No abstract text is available yet for this article.
March 15, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28270377/psychogenic-purpura-successfully-treated-with-antidepressant-therapy
#3
Şeyda Çelik Göksoy, Ayse Kılınçaslan, İlyas Kaya
No abstract text is available yet for this article.
March 8, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28270376/antioxidants-attenuate-oxidative-stress-induced-hidden-blood-loss-in-rats
#4
Hong Qian, Tao Yuan, Jian Tong, Wen Shuang Sun, Jiajia Jin, Wen Xiang Chen, Jia Meng, Nirong Bao, Jianning Zhao
Hidden blood loss (HBL), commonly seen post total knee or hip arthroplasty, causes postoperative anemia even after reinfusion or blood transfusion based on the visible blood loss volume. Recent studies demonstrated oxidative stress might be involved in HBL. However, whether antioxidants proanthocyanidin (PA) or hydrogen water (HW) can ameliorate HBL remains poorly understood. The aim of the study was to evaluate the effect of PA and HW on HBL. Rat HBL model was established through administration of linoleic acid with or without treatment of PA or HW...
March 8, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28270375/the-elusive-diagnosis-of-primary-esophageal-lymphoma
#5
Rachel Abou Mrad, Nadim El-Majzoub, Ali Shamseddine, Assaad Soweid
No abstract text is available yet for this article.
March 8, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28270374/the-assessment-of-cd56-and-cd117-expressions-at-the-time-of-the-diagnosis-in-multiple-myeloma-patients
#6
Funda Ceran, Mesude Falay, Simten Dağdaş, Gülsüm Özet
OBJECTIVE: The purpose of this study is to investigate the relationship between the CD56 and CD117 expressions and the clinical and laboratory findings in multiple myeloma (MM) patients. MATERIALS AND METHODS: Analysis of multi-parametric flow cytometry (MFC) data obtained from the diagnostic bone marrow aspirations of a total of 34 newly diagnosed MM patients were assessed retrospectively. CD56 and CD117 expressions of the patients were compared with their stages and the clinical parameters...
March 8, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28270373/phenotype-report-on-patients-with-congenital-factor-v-deficiency-in-southern-iran-in-the-recent-ten-years-experience
#7
Mohammad Mostafa Safarpour, Sezaneh Haghpanah, Aidin Meshksar, Mehran Karimi
OBJECTIVE: To investigate clinical symptoms in patients with congenital FV deficiency and the relationship between phenotype and factor activity level. MATERIAL AND METHODS: Thirteen patients with congenital FV deficiency were investigated and factor activity level and first clinical presentations were studied for each patient. RESULTS: The most common first signs and symptoms were post-surgery, post-partum, post -circumcision and post-traumatic bleeding (30...
March 8, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28270371/an-unusual-giant-leg-ulcer-as-a-rare-presentation-of-sweet-s-syndrome-in-a-patient-with-hairy-cell-leukemia-succesfully-managed-by-splenectomy
#8
Hakan Özdoğu, Mahmut Yeral, Can Boğa
No abstract text is available yet for this article.
March 8, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28270370/autoantibodies-against-carbonic-anhydrase-i-and-ii-in-patients-with-acute-myeloid-leukemia
#9
Ahmet Menteşe, Nergiz Erkut, Selim Demir, Serap Özer Yaman, Aysegül Sümer, Seniz Doğramacı, Ahmet Alver, Mehmet Sönmez
OBJECTIVE: Cancer, one of the principal causes of death, is a global social health problem. Autoantibodies developed against the organism's self-antigens are detected in the sera of subjects with cancer. In recent years carbonic anhydrase (CA) I and II autoantibodies have been shown in some autoimmune diseases and carcinomas, but the mechanisms underlying this immune response have not yet been explained. The aim of this study was to evaluate CA I and II autoantibodies in patients with acute myeloid leukemia (AML) and to provide a novel perspective regarding the autoimmune basis of the disease...
March 8, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28270368/clinical-outcomes-related-to-the-use-of-bendamustine-therapy-for-multiple-myeloma-patients-relapsed-refractory-to-imids-and-proteasome-inhibitors
#10
Fevzi Fırat Yalnız, Nihan Akkoç, Ayşe Salihoğlu, M Cem Ar, Seniz Aydın, A Emre Eşkazan, Teoman Soysal, Yıldız Aydın
Multiple myeloma (MM) patients who are relapsed or refractory to both proteasome inhibitory (PIs) and immunomodulatory drugs (IMiDs) have been reported to have poor outcome. Bendamustine has been reported to have an antitumor effect in newly diagnosed as well as relapsed refractory multiple myeloma (RRMM). The aim of this retrospective study was to evaluate the efficacy of bendamustine therapy in heavily pretreated MM patients, who were refractory to PIs and IMiDs. Nineteen RRMM patients treated either with bendamustine and steroid (n=13) or a combination of bendamustine in with novel drugs (n=6) were included...
March 8, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28218607/tet2-asxl1-idh1-and-idh2-single-nucleotide-polymorphisms-in-turkish-patients-with-chronic-myeloproliferative-neoplasms
#11
Nur Soyer, Burçin Tezcanlı Kaymaz, Melda Cömert Özkan, Çağdaş Aktan, Ali Şahin Küçükaslan, Fahri Şahin, Buket Kosova, Güray Saydam
We aimed to determine the genotype distribution, allele frequency and prognostic impact of IDH1/2(Isocitrate dehydrogenase), TET2(Ten-Eleven-Translocation2) and ASXL1(Additional Sex Combs-Like 1) single nucleotide polymorphisms (SNPs) in MPNs. TET2(rs763480), ASXL1(rs2208131) and IDH1(rs11554137) variant homozygous genotype frequencies were 1.5%, 9.2% and 2.3%, respectively. No IDH2 SNP was identified. IDH1 and TET2 frequencies were 5% in ET and 1.7% in ET, 5% in PMF, respectively. ASXL1 frequencies were 8...
February 20, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28218069/concomitant-presence-of-cd5-positive-diffuse-large-b-lymphoma-and-monoclonal-b-cells-with-cll-immunophenotype-is-it-richter-s-transformation
#12
Sabina Langer, Jasmita Dass, Suchi Mittal, Shyam Aggarwal
No abstract text is available yet for this article.
February 20, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28183687/leukemic-phase-of-cd5-diffuse-large-b-cell-lymphoma
#13
Hui Hua Hsiao, Hui Ching Wang, Yu Fen Tsai, Chien Hsiao, Shih Feng Cho, Yi Chang Liu, Sheng Fung Lin, Ta Chih Liu
No abstract text is available yet for this article.
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28183686/non-leukemic-granulocytic-sarcoma-presenting-with-multiple-lymphadenopathy
#14
Ayfer Gedük, Esra T Demirsoy, Süheyla U Bozkurt, Zafer Gülbaş, Serkan İşgören
No abstract text is available yet for this article.
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28183685/a-case-of-leukemia-cutis-with-acute-myeloid-leukemia-on-azacitidine-therapy
#15
Asude Kara, Aslı Akın Belli, Volkan Karakuş, Yelda Dere, Erdal Kurtoğlu
No abstract text is available yet for this article.
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28179213/juvenile-myelomonocytic-leukemia-in-turkey-a-retrospective-analysis-of-65-patients
#16
Özlem Tüfekçi, Ülker Koçak, Zühre Kaya, İdil Yenicesu, Canan Albayrak, Davut Albayrak, Şebnem Yılmaz Bengoa, Türkan Patıroğlu, Musa Karakükçü, Ekrem Ünal, Elif Ünal İnce, Talia İleri, Mehmet Ertem, Tiraje Celkan, Gül Nihal Özdemir, Nazan Sarper, Dilek Kaçar, Neşe Yaralı, Namık Yaşar Özbek, Alphan Küpesiz, Tuba Karapınar, Canan Vergin, Ümran Çalışkan, Hüseyin Tokgöz, Melike Sezgin Evim, Birol Baytan, Adalet Meral Güneş, Deniz Yılmaz Karapınar, Serap Karaman, Vedat Uygun, Gülsun Karasu, Mehmet Akif Yeşilipek, Ahmet Koç, Erol Erduran, Berna Atabay, Haldun Öniz, Hale Ören
OBJECTIVE: To define the status of juvenile myelomonocytic leukemia (JMML) patients in Turkey, in terms of time of diagnosis, clinical characteristics, mutational studies, clinical course and treatment strategies. MATERIALS AND METHODS: Data including clinical and labarotory characteristics and treatment strategies of JMML patients were collected retrospectively from pediatric hematology-oncology centers in Turkey. RESULTS: Sixty-five children with JMML diagnosed between 2002 and 2016 in 18 institutions throughout Turkey were enrolled into the study...
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28179212/association-between-n363s-and-bcli-polymorphisms-of-the-glucocorticoid-receptor-gene-nr3c1-and-glucocorticoid-side-effects-during-childhood-acute-lymphoblastic-leukemia-treatment
#17
Meriç Kaymak Cihan, Halil Gürhan Karabulut, Nüket Yürür Kutlay, Hatice Ilgın Ruhi, Ajlan Tükün, Lale Olcay
OBJECTIVE: Glucocorticoids (GCs) are the key drugs for the treatment of pediatric acute lymphoblastic leukemia (ALL). Herein, investigation of the relationship between the N363S and BclI polymorphisms of the GC receptor gene (NR3C1) and the side effects of GCs during pediatric ALL therapy was aimed. MATERIALS AND METHODS: N363S and BclI polymorphisms were analyzed in 49 patients with ALL treated between 2000 and 2012. Control group consisted 46 patients with benign disorders...
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28179211/primary-thrombophilia-in-m%C3%A3-xico-xii-miscarriages-are-more-frequent-in-persons-with-the-sticky-platelet-syndrome-sps
#18
Guillermo J Ruiz-Delgado, Yahveth Cantero-Fortiz, Mariana A Mendez-Huerta, Mónica Leon-Gonzalez, Ana K Nuñez-Cortes, Andrés A Leon-Peña, Juan Carlos Olivares-Gazca, Guillermo J Ruiz-Argüelles
BACKGROUND: The sticky platelet syndrome (SPS) is an inherited condition which leads into arterial and venous thrombosis. There is scant information about the association between the SPS and obstetric complications. OBJECTIVE: To assess the relationship of the SPS and fetal loss in a single institution. MATERIALS AND METHODS: The obstetric history of all the consecutive female patients prospectively studied along a 324 month period, in a single institution with a history of thrombosis and a clinical marker of primary thrombophilia was reviewed...
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28148470/diagnostic-accuracy-of-interleukin-6-interleukin-8-and-interleukin-10-for-predicting-bacteremia-in-children-with-febrile-neutropenia
#19
Zümrüt Şahbudak Bal, Nihal Karadaş Özdemir, Semra Şen, Deniz Yılmaz Karapınar, Elif Azarsız, Şöhret Aydemir, Fadıl Vardar
Despite improvements in diagnosis and treatment, infections are still major cause of morbidity and mortality in children with febrile neutropenia. In majority of febrile episodes, infection source cannot be defined. In this study, we aim to identify the earlier predictors of bacteremia/fungemia and a useful cytokine identify the source of infections and to discriminate the patients with culture-confirmed bacterial/fungal infection. The most sensitive cytokine was IL (Interleukin)-10 and the most specific was IL-8 in predicting culture-confirmed...
February 1, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28148469/prognostic-value-of-mirna-155-expression-in-b-cell-non-hodgkin-s-lymphoma
#20
Ahmed M L Bedewy, Shereen M Elmaghraby, Ahmed A Shehata, Noha S Kandil
OBJECTIVE: miRNA-155 resides within the B-cell Integration Cluster [BIC] gene on chromosome 21. It can act either as oncogene or as tumor suppressor gene, depending on the cell background in which miRNA-155 is performing its specific target gene controlling function. Therefore, the aim of this study was to investigate miRNA-155 expression in patients with B-cell Non Hodgkin's lymphoma (NHL) and its relation to disease prognosis in diffuse large B cell lymphoma (DLBCL) patients. MATERIALS AND METHODS: RT-PCR assay was performed to evaluate the expression levels of miRNA-155 in 84 patients with newly diagnosed B-NHL and 15 normal controls...
February 1, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
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