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Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology

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https://www.readbyqxmd.com/read/28218607/tet2-asxl1-idh1-and-idh2-single-nucleotide-polymorphisms-in-turkish-patients-with-chronic-myeloproliferative-neoplasms
#1
Nur Soyer, Burçin Tezcanlı Kaymaz, Melda Cömert Özkan, Çağdaş Aktan, Ali Şahin Küçükaslan, Fahri Şahin, Buket Kosova, Güray Saydam
We aimed to determine the genotype distribution, allele frequency and prognostic impact of IDH1/2(Isocitrate dehydrogenase), TET2(Ten-Eleven-Translocation2) and ASXL1(Additional Sex Combs-Like 1) single nucleotide polymorphisms (SNPs) in MPNs. TET2(rs763480), ASXL1(rs2208131) and IDH1(rs11554137) variant homozygous genotype frequencies were 1.5%, 9.2% and 2.3%, respectively. No IDH2 SNP was identified. IDH1 and TET2 frequencies were 5% in ET and 1.7% in ET, 5% in PMF, respectively. ASXL1 frequencies were 8...
February 20, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28218069/concomitant-presence-of-cd5-positive-diffuse-large-b-lymphoma-and-monoclonal-b-cells-with-cll-immunophenotype-is-it-richter-s-transformation
#2
Sabina Langer, Jasmita Dass, Suchi Mittal, Shyam Aggarwal
No abstract text is available yet for this article.
February 20, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28183687/leukemic-phase-of-cd5-diffuse-large-b-cell-lymphoma
#3
Hui Hua Hsiao, Hui Ching Wang, Yu Fen Tsai, Chien Hsiao, Shih Feng Cho, Yi Chang Liu, Sheng Fung Lin, Ta Chih Liu
No abstract text is available yet for this article.
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28183686/non-leukemic-granulocytic-sarcoma-presenting-with-multiple-lymphadenopathy
#4
Ayfer Gedük, Esra T Demirsoy, Süheyla U Bozkurt, Zafer Gülbaş, Serkan İşgören
No abstract text is available yet for this article.
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28183685/a-case-of-leukemia-cutis-with-acute-myeloid-leukemia-on-azacitidine-therapy
#5
Asude Kara, Aslı Akın Belli, Volkan Karakuş, Yelda Dere, Erdal Kurtoğlu
No abstract text is available yet for this article.
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28179213/juvenile-myelomonocytic-leukemia-in-turkey-a-retrospective-analysis-of-65-patients
#6
Özlem Tüfekçi, Ülker Koçak, Zühre Kaya, İdil Yenicesu, Canan Albayrak, Davut Albayrak, Şebnem Yılmaz Bengoa, Türkan Patıroğlu, Musa Karakükçü, Ekrem Ünal, Elif Ünal İnce, Talia İleri, Mehmet Ertem, Tiraje Celkan, Gül Nihal Özdemir, Nazan Sarper, Dilek Kaçar, Neşe Yaralı, Namık Yaşar Özbek, Alphan Küpesiz, Tuba Karapınar, Canan Vergin, Ümran Çalışkan, Hüseyin Tokgöz, Melike Sezgin Evim, Birol Baytan, Adalet Meral Güneş, Deniz Yılmaz Karapınar, Serap Karaman, Vedat Uygun, Gülsun Karasu, Mehmet Akif Yeşilipek, Ahmet Koç, Erol Erduran, Berna Atabay, Haldun Öniz, Hale Ören
OBJECTIVE: To define the status of juvenile myelomonocytic leukemia (JMML) patients in Turkey, in terms of time of diagnosis, clinical characteristics, mutational studies, clinical course and treatment strategies. MATERIALS AND METHODS: Data including clinical and labarotory characteristics and treatment strategies of JMML patients were collected retrospectively from pediatric hematology-oncology centers in Turkey. RESULTS: Sixty-five children with JMML diagnosed between 2002 and 2016 in 18 institutions throughout Turkey were enrolled into the study...
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28179212/association-between-n363s-and-bcli-polymorphisms-of-the-glucocorticoid-receptor-gene-nr3c1-and-glucocorticoid-side-effects-during-childhood-acute-lymphoblastic-leukemia-treatment
#7
Meriç Kaymak Cihan, Halil Gürhan Karabulut, Nüket Yürür Kutlay, Hatice Ilgın Ruhi, Ajlan Tükün, Lale Olcay
OBJECTIVE: Glucocorticoids (GCs) are the key drugs for the treatment of pediatric acute lymphoblastic leukemia (ALL). Herein, investigation of the relationship between the N363S and BclI polymorphisms of the GC receptor gene (NR3C1) and the side effects of GCs during pediatric ALL therapy was aimed. MATERIALS AND METHODS: N363S and BclI polymorphisms were analyzed in 49 patients with ALL treated between 2000 and 2012. Control group consisted 46 patients with benign disorders...
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28179211/primary-thrombophilia-in-m%C3%A3-xico-xii-miscarriages-are-more-frequent-in-persons-with-the-sticky-platelet-syndrome-sps
#8
Guillermo J Ruiz-Delgado, Yahveth Cantero-Fortiz, Mariana A Mendez-Huerta, Mónica Leon-Gonzalez, Ana K Nuñez-Cortes, Andrés A Leon-Peña, Juan Carlos Olivares-Gazca, Guillermo J Ruiz-Argüelles
BACKGROUND: The sticky platelet syndrome (SPS) is an inherited condition which leads into arterial and venous thrombosis. There is scant information about the association between the SPS and obstetric complications. OBJECTIVE: To assess the relationship of the SPS and fetal loss in a single institution. MATERIALS AND METHODS: The obstetric history of all the consecutive female patients prospectively studied along a 324 month period, in a single institution with a history of thrombosis and a clinical marker of primary thrombophilia was reviewed...
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28148470/diagnostic-accuracy-of-interleukin-6-interleukin-8-and-interleukin-10-for-predicting-bacteremia-in-children-with-febrile-neutropenia
#9
Zümrüt Şahbudak Bal, Nihal Karadaş Özdemir, Semra Şen, Deniz Yılmaz Karapınar, Elif Azarsız, Şöhret Aydemir, Fadıl Vardar
Despite improvements in diagnosis and treatment, infections are still major cause of morbidity and mortality in children with febrile neutropenia. In majority of febrile episodes, infection source cannot be defined. In this study, we aim to identify the earlier predictors of bacteremia/fungemia and a useful cytokine identify the source of infections and to discriminate the patients with culture-confirmed bacterial/fungal infection. The most sensitive cytokine was IL (Interleukin)-10 and the most specific was IL-8 in predicting culture-confirmed...
February 1, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28148469/prognostic-value-of-mirna-155-expression-in-b-cell-non-hodgkin-s-lymphoma
#10
Ahmed M L Bedewy, Shereen M Elmaghraby, Ahmed A Shehata, Noha S Kandil
OBJECTIVE: miRNA-155 resides within the B-cell Integration Cluster [BIC] gene on chromosome 21. It can act either as oncogene or as tumor suppressor gene, depending on the cell background in which miRNA-155 is performing its specific target gene controlling function. Therefore, the aim of this study was to investigate miRNA-155 expression in patients with B-cell Non Hodgkin's lymphoma (NHL) and its relation to disease prognosis in diffuse large B cell lymphoma (DLBCL) patients. MATERIALS AND METHODS: RT-PCR assay was performed to evaluate the expression levels of miRNA-155 in 84 patients with newly diagnosed B-NHL and 15 normal controls...
February 1, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28120779/genotype-phenotype-correlations-of-%C3%AE-thalassemia-mutations-in-azerbaijani-population
#11
Chingiz Asadov, Eldar Abdulalimov, Tahira Mammadova, Surmaya Gafarova, Yegana Guliyeva, Gunay Aliyeva
OBJECTIVE: β-Thalassemia is the most common inherited disorder in Azerbaijan. The aim of our study was to reveal genotype-to-phenotype correlations of the most common β-thalassemia mutations in Azerbaijani population. Patients with Codon 8 (-AA), IVS-I-6 (T>C) and IVS-II-1 (G>A) mutations, which are reportedly the most common β-globin gene mutations among local population were tested for hematologic parameters. MATERIALS AND METHODS: 55 previously tested patients with known genotypes were included to the study...
January 25, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28120778/flaming-plasma-cell-leukemia
#12
Reza Ranjbaran, Habibollah Golafshan
No abstract text is available yet for this article.
January 25, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28077343/disappearance-of-acquired-hemophilia-a-after-complete-remission-in-a-multiple-myeloma-patient
#13
Vanessa Innao, Alessandro Allegra, Rosalba Morreale, Sabina Russo, Caterina Musolino
No abstract text is available yet for this article.
January 12, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28052839/the-second-and-third-hemoglobin-kansas-cases-in-the-turkish-population
#14
Zeynep Kayra Tanrıverdi, Arzu Akyay, Aşkın Şen, Çağatay Taşkapan, Ünsal Özgen
No abstract text is available yet for this article.
January 2, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28044994/influence-of-l-carnitine-on-stored-rat-blood-a-study-on-plasma
#15
Carl Hsieh, Vani Rajashekharaiah
OBJECTIVE: Plasma acts as a good indicator of oxidative stress in blood. L-carnitine is an antioxidant that reduces metabolic stress in cells, thereby providing a protective effect against oxidative stress. L-carnitine as an additive in storage has not been explored. Thus, this study attempts to analyze the role of L-carnitine in blood storage solution, Citrate Phosphate Dextrose Adenine (CPDA)-1 through oxidative stress (OS) markers - antioxidant enzymes, lipid peroxidation and protein oxidation...
December 30, 2016: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28044992/assesment-quality-of-life-for-chronic-myeloid-leukemia-patients-by-using-eortcqol-c30
#16
Mehmet Can Uğur, Yaşar Bekir Kutbay, Özge Özer Kaya, Cengiz Ceylan
No abstract text is available yet for this article.
December 30, 2016: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28008859/subcutaneous-myeloma-deposit-in-the-region-of-arteriovenous-fistula
#17
Petar Djuric, Aleksandar Jankovic, Zoran Milojevic, Katarina Markovic, Slavisa Sekulic, Milan Pantelic, Jelena Tosic Dragovic, Ana Bulatovic, Nada Dimkovic
No abstract text is available yet for this article.
December 23, 2016: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28008858/refractory-leukaemic-cutaneous-cd3-tcr-phenotype-t-cell-lymphoma-with-complete-remission-after-allogeneic-stem-cell-transplantation
#18
Hatice Şanlı, Bengü Nisa Akay, Seçil Saral, Aylin Okçu Heper, Pervin Topçuoğlu
No abstract text is available yet for this article.
December 23, 2016: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/27956374/current-review-of-iron-overload-and-related-complications-in-hematopoietic-stem-cell-transplantation
#19
Erden Atilla, Selami K Toprak, Taner Demirer
Iron overload is an adverse prognostic factor for patients undergoing hematopoietic stem cell transplantation (HSCT). In HSCT setting, pretransplant and early posttransplant ferritin and transferrin saturation were found to be highly elevated due to high transfusion requirements. In addition to that, post-HSCT iron overload had shown to be related with infections, hepatic sinusoidal obstruction syndrome (SOS), mucositis, liver dysfunction and acute GVHD. Hyperferritinemia causes decreased survival rates in both pre and post transplant setting...
December 12, 2016: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/27956373/acute-myocardial-infarction-due-to-eltrombopag-therapy-in-a-patient-with-immune-thrombocytopenic-purpura
#20
Sena Sert, Hasan Özdil, Murat Sünbül
No abstract text is available yet for this article.
December 12, 2016: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
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