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World Journal of Clinical Cases

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https://www.readbyqxmd.com/read/29204429/acid-suppressive-therapy-improved-symptoms-due-to-circumferential-cervical-inlet-patch-with-proton-pumps-h-k-atpase
#1
Takanori Yamada, Atsushi Tsuji, Shunya Onoue, Masanao Kaneko, Fumihiko Tanioka, Satoshi Osawa, Yasuhiko Saida
Cervical inlet patch (CIP), also referred to as esophageal heterotopic gastric mucosa, is regarded as the residue of columnar epithelium of the embryonic esophagus. Narrow band imaging increases the detection rate of CIP. Herein, we present a 55-year-old man with symptomatic circumferential inlet patch. He exhibited globus and dysphagia, and esophagogastroduodenoscopy found cir-cumferential CIP, where im-munohistochemistry revealed the existence of pro-ton pumps (H+, K+-ATPase). His throat symptoms were relieved by acid suppressive therapy with pump inhibitors...
November 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29204428/case-of-gastric-neuroendocrine-carcinoma-showing-an-interesting-tumorigenic-pathway
#2
Noriyuki Uesugi, Ryo Sugimoto, Makoto Eizuka, Yasuko Fujita, Mitsumasa Osakabe, Keisuke Koeda, Takashi Kosaka, Shunichi Yanai, Kazuyuki Ishida, Akira Sasaki, Takayuki Matsumoto, Tamotsu Sugai
Here, we report a case of gastric neuroendocrine carcinoma showing an interesting tumorigenic pathway. A 57-year-old Japanese woman presented with epigastric tenderness, and distal gastrectomy was performed. In the surgical specimen, histologically, the tumor tissue was composed of three subtypes of tumor components showing different histological architecture and cellular atypia, diagnosed as neuroendocrine tumor (NET) G2, NET G3, and neuroendocrine carcinoma (NEC) components. Immunohistochemically, the Ki-67-positive rates of NET G2, NET G3, and NEC components were 6...
November 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29204427/natural-killer-cells-activity-in-a-metastatic-colorectal-cancer-patient-with-complete-and-long-lasting-response-to-therapy
#3
Alessandro Ottaiano, Maria Napolitano, Monica Capozzi, Salvatore Tafuto, Antonio Avallone, Stefania Scala
Here we report a case of a 70-year-old man who received adjuvant chemotherapy with fluorouracile, folinic acid and oxaliplatin after a left hemicolectomy for a stage IIIb adenocarcinoma in May 2009. During follow-up he de-veloped abdominal lymphnodes metastases evidenced by positron emission tomography- computed tomography (PET-CT) scan and increase of carcinoembryonic antigen (CEA) level. Chemotherapy with capecitabine, oxaliplatin and bevacizumab was started in April 2012. Restaging showed a complete response and normalization of CEA...
November 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29085830/prosthodontic-management-of-hemimandibulectomy-patients-to-restore-form-and-function-a-case-series
#4
Deenadayalan Lingeshwar, Rajendran Appadurai, Ujjayanthi Sswedheni, Challa Padmaja
Surgical resection of mandible owing to benign, malignant neoplasm, osteoradionecrosis is common. The resection can be total or segmental depending on the lesion. Loss of mandibular continuity causes deviation of remaining mandibular segment towards the resected side and rotation inferiorly due to muscle pull and scar contracture affecting mastication and esthetics. Surgical reconstruction may not be always possible. Prosthetic rehabilitation plays a major role in these patients. This case series describes different types of guiding flange (GF) prosthesis with modifications for three hemimandibulectomy patients at different time interval after surgery...
October 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29085829/juvenile-hemochromatosis-hamp-mutation-and-severe-iron-overload-treated-with-phlebotomies-and-deferasirox
#5
Manuel A Lescano, Letícia C Tavares, Paulo C J L Santos
Juvenile hemochromatosis (JH) is a rare condition classified as an autosomal recessive disorder that leads to severe iron absorption. JH usually affects people under the age of 30 and presents symptoms such as chronic liver damage, hypogonadotropic hypogonadism, cardiac diseases and endocrine dysfunctions. The present case reports a 29-year-old Brazilian woman with JH condition due to HAMP mutation (g.47G>A), treated with phlebotomies and deferasirox. She presented symptoms such as weakness, skin hyperpigmentation, joint pain in the shoulders and hands and amenorrhea...
October 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29085828/hydrogen-peroxide-ingestion-with-injury-to-upper-gastrointestinal-tract
#6
Jonathan V Martin, Choichi Sugawa
Hydrogen peroxide is a common over-the-counter solution that has developed a growing body of literature regarding toxic ingestion. Intentional ingestion of high concentration hydrogen peroxide for health purposes has gained popularity in certain patient populations; purported benefits are due to the increased oxygen released into the blood stream. We present for evaluation one such case with associated imaging that presented to our urban medical center. A brief review of the literature was also performed noting current recommendations regarding both outcomes and indications for endoscopy as well as hyperbaric oxygen therapy following ingestion of hydrogen peroxide...
October 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29085827/adrenal-ganglioneuroma-what-you-need-to-know
#7
REVIEW
Konstantinos S Mylonas, Dimitrios Schizas, Konstantinos P Economopoulos
Adrenal ganglioneuromas (GNs) constitute rare, differentiated tumors which originate from neural crest cells. GNs are usually hormonally silent and tend to be discovered incidentally on imaging tests. Adrenalectomy is the gold standard for the treatment of primary adrenal GNs. Nevertheless, preoperative differential diagnosis of GNs remains extremely challenging, and thus histopathological examination is required in order to confirm the diagnosis of GN. Overall, prognosis after surgical resection seems to be excellent, without any recurrences or need for adjuvant therapy...
October 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29026836/anti-n-methyl-d-aspartate-receptor-encephalitis-that-aggravates-after-acinetobacter-baumannii-pneumonia-a-case-report
#8
Cheng C Wang, Da J Li, Yi Q Xia, Kai Liu
We report an atypical case of anti-N-methyl-D-aspartate receptor encephalitis (ANMDARE). A 27-year-old man diagnosed with ANMDARE received immunotherapy and had a good recovery. However, within one month, he developed severe status epilepticus and decreased level of conscience with new hyperpyrexia and dyspnea, and was admitted to the emergency intensive care unit. Acinetobacter baumanii were found in the sputum culture; and anti-NMDAR antibodies were positive (titer: 1/80) in the cerebrospinal fluid. Repeated immunotherapy was administered with antibacterial agents, and the patient recovered except for mild psychiatric sequelae...
September 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29026835/recurrent-aneurysmal-bone-cyst-of-talus-resulted-in-tibiotalocalcaneal-arthrodesis
#9
Amir R Vosoughi, Kamran Mozaffarian, Mohammad A Erfani
Aneurysmal bone cyst (ABC), a locally benign aggressive lytic lesion of either primary or secondary origin, seldom involves the talus. Herein, we present a 25-year-old man with recurrent ABC of the talus after curettage and bone grafting, which was managed by total resection followed by filling the defect using fibular graft and finally tibiotalocalcaneal arthrodesis due to articular surface involvement. At 18 mo postoperatively, no recurrence was detected. Arthrodesis might be a good option in cases with recurrent ABC of the talus especially with articular surface involvement...
September 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29026834/conservative-approach-to-the-acute-management-of-a-large-mesenteric-cyst
#10
Billy C Leung, Ruth Sankey, Matteo Fronza, Mohamed Maatouk
Mesenteric cysts are rare, benign gastrointestinal cystic lesions, which are often non-troublesome and present as an incidental radiological finding. However, surgery is often performed in the acute setting to remove lesions that are symptomatic. This report highlights the case of a large, symptomatic mesenteric cyst managed successfully with initial conservative measures followed by planned elective surgery. A 44-year-old female presented with a four-day history of generalised abdominal pain associated with distension, fever, diarrhoea and vomiting...
September 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29026833/primary-prevention-of-cardiovascular-disease-in-older-adults-in-china
#11
REVIEW
Jian Yong, Dong Lin, Xue-Rui Tan
Over the past two decades, the percentage of Chinese who is 60 years or older has increased from 5.2% in 1995 to 10.5% in 2015. Approximately 16% of the population in China was 60 years old and above in 2015. Since 1990, cardiovascular disease (CVD) has been the leading cause of death in China. Cardiovascular medications of older adults are usually more complicated than younger age groups due to polypharmacy, the presence of comorbidities and more susceptible to treatment-related adverse outcomes. Therefore, effective primary prevention of CVD for older adults is important in sustaining the health of older adults and reducing the burden of the healthcare system...
September 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28868307/atlanto-axial-langerhans-cell-histiocytosis-in-a-child-presented-as-torticollis
#12
Miniar Tfifha, Mehdi Gaha, Nadia Mama, Mohamed Taher Yacoubi, Saoussen Abroug, Hela Jemni
Langerhans cell histiocytosis (LCH) is a rare condition mostly seen in children and adolescents. Eosinophilic granuloma (EG) is one of its three clinical entities and is considered as a benign osteolytic lesion. Many reports of patients with spine histiocytosis are well documented in the literature but it is not the case of atlantoaxial localization. We report here a new observation of atlantoaxial LCH in a 4-year-old boy revealed by persistent torticollis. He was successfully treated with systemic chemotherapy and surgery...
August 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28868306/pseudotumoral-acute-cerebellitis-associated-with-mumps-infection-in-a-child
#13
Houda Ajmi, Mehdi Gaha, Sameh Mabrouk, Saida Hassayoun, Noura Zouari, Jalel Chemli, Saoussen Abroug
Pseudotumoral cerebellitis in childhood is an uncommon presentation of cerebellitis mimicking a brain tumor. It often follows an inflammatory or infectious event, particularly due to varicella virus. Patients could have a wide clinical spectrum on presentation. Some patients may be asymptomatic or present at most with mild cerebellar signs, whereas others may suffer severe forms with brainstem involvement and severe intracranial hypertension mimicking tumor warranting surgical intervention. Imaging techniques especially multimodal magnetic resonance imaging represent an interesting tool to differentiate between posterior fossa tumors and acute cerebellitis...
August 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28868305/vertebroplasty-and-delayed-subdural-cauda-equina-hematoma-review-of-literature-and-case-report
#14
Maria Pia Tropeano, Biagia La Pira, Lorenzo Pescatori, Manolo Piccirilli
Vertebroplasy is considered an alternative and effective treatment of painful oncologic spine disease. Major complications are very rare, but with high morbidity and occur in less than 1% of patients who undergo vertebroplasty. Spinal subdural hematoma (SDH) is an extremely rare complication, usual developing within 12 h to 24 h after the procedure. We report the case of a tardive SDH in an oncologic patient who underwent VP for Myxoid Liposarcoma metastasis. Trying to explain the pathogenesis, we support the hypothesis that both venous congestion of the vertebral venous plexus of the vertebral body and venous congestion due to a traumatic injury can provoke SDH...
August 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28868304/treatment-of-sepsis-what-is-the-antibiotic-choice-in-bacteremia-due-to-carbapenem-resistant-enterobacteriaceae
#15
REVIEW
Fatema Alhashem, Nicolette Leonie Tiren-Verbeet, Emine Alp, Mehmet Doganay
Sepsis is one of the major challenges of today. Although gram-positive bacteria related infections are more prevalent in hospital setting, the highest mortality rate is associated with gram-negative microorganisms especially Enterobacteriaceae. Enterobacteriaceae, including Escherichia coli, Klebsiella spp., Proteus spp., Enterobacter spp. and Serratia spp. Resistance to β-lactams in Enterobacteriaceae is primarily attributed to the production of B-lactamase enzymes with subsequent antibiotic hydrolysis and to a lesser extent by alteration of efflux pump or porins expression...
August 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28868303/adjuvants-to-local-anesthetics-current-understanding-and-future-trends
#16
EDITORIAL
Amlan Swain, Deb Sanjay Nag, Seelora Sahu, Devi Prasad Samaddar
Although beneficial in acute and chronic pain management, the use of local anaesthetics is limited by its duration of action and the dose dependent adverse effects on the cardiac and central nervous system. Adjuvants or additives are often used with local anaesthetics for its synergistic effect by prolonging the duration of sensory-motor block and limiting the cumulative dose requirement of local anaesthetics. The armamentarium of local anesthetic adjuvants have evolved over time from classical opioids to a wide array of drugs spanning several groups and varying mechanisms of action...
August 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28798927/is-dengue-emerging-as-important-cause-of-acute-liver-failure-in-endemic-regions
#17
Lavleen Singh, Amitabh Singh, Mitali Agarwal, Sataroopa Mishra
Dengue virus infection continues to be major public health problem in large part of world. The epidemiology of dengue viral infection is becoming increasingly complex and has substantially changed over almost past six decades not only in terms of prevalent strains and geographical locations but also in terms of disease severity and atypical presentations. Though liver is the most common organ affected but is generally asymptomatic. We present a case of infant with severe dengue who died of fulminant hepatic failure and showed pan lobular necrosis on post mortem liver biopsy...
July 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28798926/rare-case-of-cryptogenic-brain-abscess-caused-by-raoultella-ornithinolityca
#18
Marianna Luongo
Cerebral abscess is a potentially fatal neurosurgical condition, despite improvements in technology, new antimicrobial agents and modern neurosurgical instruments and techniques. I report the case of a 64-year-old woman, affected by a right frontobasal brain abscess, compressing the homolateral frontal horn of lateral ventricle, with a second mass partially occupying the right orbital cavity. She presented also with inflammatory sinusopathy involving the right maxillary, ethmoid and frontal sinuses. After 14 d of clinical observation and antimicrobial therapy, the patient received a computed tomography scan, which showed growth of the cerebral mass, with a ring of peripheral contrast enhancement and surrounding edema...
July 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28798925/post-traumatic-dural-sinus-thrombosis-following-epidural-hematoma-literature-review-and-case-report
#19
Lorenzo Pescatori, Maria Pia Tropeano, Cristina Mancarella, Emiliano Prizio, Giorgio Santoro, Maurizio Domenicucci
Dural sinus thrombosis following a head trauma is a rare condition, described in literature along with the lack of consensus regarding diagnosis and management. We present a case of a fifty-year-old man with a head injury and combined supratentorial-subtentorial epidural hematoma who was treated conservatively through the administration of low molecular weight heparin. The diagnosis and management of this condition are discussed based on a literature review. The early diagnosis may prevent potentially treatable poor outcomes...
July 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28798924/diagnostic-performance-of-high-resolution-computed-tomography-in-otosclerosis
#20
Todd Kanzara, Jagdeep Singh Virk
AIM: To determine the sensitivity and specificity of high resolution computed tomography (HRCT) in the diagnosis of otosclerosis. METHODS: A systematic literature review was undertaken to include Level I-III studies (Oxford Centre for Evidenced based Medicine) that utilised HRCT to detect histology confirmed otosclerosis. Quantitative synthesis was then performed. RESULTS: Based on available level III literature, HRCT has a relatively low sensitivity of 58% (95%CI: 49...
July 16, 2017: World Journal of Clinical Cases
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