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Clinical Medicine Insights. Ear, Nose and Throat

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https://www.readbyqxmd.com/read/30147388/how-does-smoking-change-the-clinicopathological-characteristics-of-human-papillomavirus-positive-oropharyngeal-squamous-cell-carcinoma-one-medical-center-experience
#1
Changxing Liu, Guy Talmor, Garren Mi Low, Tiffany V Wang, Daljit S Mann, Uttam K Sinha, Niels C Kokot
Introduction: Human papillomavirus (HPV)-positive and HPV-negative oropharyngeal squamous cell carcinomas (OPSCCs) are 2 distinct cancers, with HPV-positivity conferring a better prognosis. Smoking status is a complicating factor for both patient populations. There have been scattered literature that have reported on incomplete information regarding the profiles of their patient population. Details including age and sex distributions, TNM staging, histology grading, recurrence time and types, death rates, and the direct causes of deaths have been reported incompletely in the literature...
2018: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/30093799/effects-of-resonance-voice-therapy-on-hormone-related-vocal-disorders-in-professional-singers-a-pilot-study
#2
Laishyang Melody Ouyoung, Brenda Capobres Villegas, Changxing Liu, Guy Talmor, Uttam K Sinha
Background: Menstruation-related hormonal alteration can be detrimental to the professional singing voice of women. Resonance Voice Therapy (RVT) has been proven to improve vocal production. However, no research to date has been conducted examining the subjective, acoustic, and stroboscopic effects of RVT on professional female singers having premenstrual or postmenopausal voice disorders. Aim: The aim of this study is to compare the vocal effects of RVT with a control cervical-thoracic intervention in healthy female singers during the premenstrual phase as well as in postmenopausal singers and to evaluate which intervention will allow singers to improve vocal performance regardless of changes in hormonal status...
2018: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/30090023/characteristics-of-sinus-fungus-ball-a-unique-form-of-rhinosinusitis
#3
Rong-San Jiang, Wan-Chun Huang, Kai-Li Liang
Objective: The purpose of this study was to investigate the characteristics of this unique form of rhinosinusitis. Methods: Ninety-one patients with sinus fungus balls were evaluated for clinical characteristics. Nasal tissues obtained from 38 patients with sinus fungus ball, along with 26 controls were used for histopathological, cytokines/chemokines, western blotting, and genetic analyses. Results: Patients with fungus balls had significantly more females and their age was older...
2018: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/30013412/anterior-midline-glossotomy-approach-for-large-schwannoma-of-the-tongue-case-report
#4
Johanna Diplan, Paola Cavallo, Seyla de Los Santos
Schwannoma corresponds to a benign neurogenic tumor, derived from neural crest cells. It accounts for approximately 5% of all benign soft tissue tumors. These are the most common cause of peripheral nerve neoplasms of the oral cavity and oropharynx representing 1%. Isolated or solitary neurofibromas of the oral cavity usually involve the tongue or the labial mucosa. They appear as soft, painless, slow-growing masses that are tender to depression or palpation. The case of a 40-year-old woman is studied because of the presence of painless swelling, slow, and progressive growth of the oral language...
2018: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/29531480/prognostic-value-and-changes-of-auditory-brain-stem-response-in-children-with-bacterial-meningitis-in-luanda-angola
#5
Mariia Karppinen, Atte Sjövall, Tuula Pelkonen, Luis Bernardino, Irmeli Roine, Anne Pitkäranta, Antti A Aarnisalo, Päivi Nevalainen, Leena Lauronen
Objective: To assess the role of single and repeated auditory brain stem response (ABR) in predicting mortality and severe neurological injury among children having bacterial meningitis (BM) in Luanda, Angola. Methods: The morphology of ABR traces of 221 children (aged 2 months to 12 years) from admission day was analyzed and compared with age-matched normative data. Absence and delay of traces were compared with mortality and mortality or severe neurological injury in subgroup analyses...
2018: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/29531479/intraoperative-functional-endoscopic-sinus-surgery-training-efficient-teaching-techniques-a-new-method
#6
Henya Sandhaus, Philip G Chen
Introduction: Functional endoscopic sinus surgery is a complex procedure used by otorhinolaryngologists to treat a host of nasal sinus pathologies. Due to the involved nasal anatomy and the nature of the procedure, teaching residents to use an endoscope is challenging. Simulation labs have been helpful but intraoperative instruction can still present difficulty in communication between resident and attending physicians during the teaching process. The purpose of this is to hypothesize a method of teaching intraoperatively that can be used supplemental to or independently of virtual reality teaching...
2018: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/29348711/efficacy-of-empirical-therapy-with-combined-ciprofloxacin-versus-topical-drops-alone-in-patients-with-tubotympanic-chronic-suppurative-otitis-media-a-randomized-double-blind-controlled-trial
#7
Maisam Abbas Onali, Syeda Beenish Bareeqa, Sadaf Zia, Syed Ijlal Ahmed, Asneha Owais, Ahmad Nawaz Ahmad
Background: One of the prevailing otologic infections in our country is chronic suppurative otitis media, especially the tubotympanic type for which various treatment protocols are followed. Usually, oral and topical antibiotics (mainly quinolones) are given alone or in combination. There is a lack of consensus as to whether topical drops alone are effective or a combined oral and systemic therapy should be prescribed. In our study, we have attempted to observe the efficacy of empirical therapy with combined ciprofloxacin versus topical drops only in patients with tubotympanic chronic suppurative otitis media for control of infection...
2018: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/29343999/targeted-treatment-with-radio-frequency-ablation-for-lingual-tonsil
#8
Suvi Renkonen, Antti A Mäkitie, Leif Bäck
Objectives: Benign enlargement of the lingual tonsils due to various causes may cause symptoms that warrant treatment. Conventional lingual tonsillectomy remains a challenging procedure, and there is no established standard procedure. We aimed to review the patients receiving different methods of lingual tonsil surgery for various indications at our institute. Methods: Retrospective clinical data on all patients with an ablative operation of the tongue base during the 8-year period between 2007 and 2014 at the Helsinki University Hospital, Helsinki, Finland, were reviewed...
2018: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/29326537/total-ossicular-replacement-prosthesis-a-new-fat-interposition-technique
#9
Issam Saliba, Valérie Sabbah, Jackie Bibeau Poirier
Objective: To compare audiometric results between the standard total ossicular replacement prosthesis (TORP-S) and a new fat interposition total ossicular replacement prosthesis (TORP-F) in pediatric and adult patients and to assess the complication and the undesirable outcome. Study design: This is a retrospective study. Methods: This study included 104 patients who had undergone titanium implants with TORP-F and 54 patients who had undergone the procedure with TORP-S between 2008 and 2013 in our tertiary care centers...
2018: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/29276420/effects-of-minerva-orthosis-on-larynx-height-in-young-healthy-volunteers
#10
Pegah Saddat Hosseini, Mohammad Taghi Karimi, Saeideh Moayedfar, Marzieh Golabbakhsh, Fatemeh Abnavi
Background: During speech, larynx is higher in the neck for high-pitched sounds and lower for low-pitched sounds. Patients with different problems in cervical and cervicothoracic spine use cervical orthosis to limit cervical motion. This study aimed to evaluate the effects of Minerva orthosis on larynx height in young, healthy volunteers. Subjects and methods: This study included 18 subjects. Acoustic measurement of frequency variability has been assessed in 3 brace conditions: (1) without brace, (2) with brace, and (3) 30 minutes after wearing the brace...
2017: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/29276419/lessons-from-unilateral-loss-of-cilia-early-nasal-nitric-oxide-gas-mixing-and-the-role-of-sinus-patency-in-determining-nasal-nitric-oxide
#11
Kenneth Rodriguez, Benjamin Gaston, Jay Wasman, Nadzeya Marozkina
Nasal nitric oxide (nNO) measurement is a diagnostic test for primary ciliary dyskinesia (PCD). Here, we have shown the development of unilateral PCD-like symptoms associated with low nNO. A 60-year-old man had been previously healthy but developed unilateral, severe pansinusitis. He required surgical drainage of all left sinuses, and biopsies showed loss of the ciliated epithelium. At 4 weeks, he had unilateral (left-sided), profuse, clear rhinorrhea characteristic of PCD, and his surgical ostia were all patent endoscopically...
2017: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/29200896/methamphetamine-use-with-subsequent-thyrotoxicosis-thyroid-storm-agranulocytosis-and-modified-total-thyroidectomy-a-case-report
#12
Omar Viswanath, Deanna C Menapace, Don B Headley
Thyroid storm is a rare, potentially lethal condition involving collapse of the hypothalamic-pituitary-thyroid feedback loop. Thyroid storm carries a significant mortality rate, thus requiring prompt identification and treatment. A 47-year-old woman presented to the emergency department complaining of palpitations, shortness of breath, and emesis for 24 hours after using methamphetamine. Past medical history was significant for untreated hyperthyroidism. Physical examination revealed a prominent, palpable thyroid...
2017: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/29114160/clinical-characteristics-of-troublesome-pediatric-tinnitus
#13
Annett Szibor, Topi Jutila, Antti Mäkitie, Antti Aarnisalo
Objectives: The frequency of tinnitus in children and adults is practically the same. However, although adults reveal their symptoms and seek for medical aid, the suffering often remains unrecognized in the young. This is due to both the inability of children to properly describe their symptoms and the lack of recognition. Materials and methods: Among 5768 patients entering our department with complaints of tinnitus between 2010 and 2015, there were only 112 children...
2017: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/28979177/yellow-nail-syndrome-with-dramatic-improvement-of-nail-manifestations-after-endoscopic-sinus-surgery
#14
Yu Hosokawa, Akihito Kuboki, Aya Mori, Hiroaki Kanaya, Tsuguhisa Nakayama, Shinichi Haruna
OBJECTIVES: Yellow nail syndrome (YNS) is a rare disease of unknown cause characterized by the triad of yellow nails, respiratory manifestations, and lymphedema. Although several therapies for YNS have been reported, there is no common consensus in the treatment. In this case report, we present a case of 56-year-old woman with YNS, whose nail manifestation was dramatically improved after endoscopic sinus surgery for the treatment of chronic rhinosinusitis. METHODS: Endoscopic sinus surgery involving middle meatal antrostomy was performed for the case of YNS with chronic rhinosinusitis and bronchiectasis resistant to antibacterial drugs...
2017: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/28904526/a-case-of-a-very-elongated-styloid-process
#15
YaLi Liu, Huaian Yang, Xiangguo Cui
Eagle syndrome is characterized by recurrent pain in the oropharynx and face due to an elongated styloid process or calcified stylohyoid ligament. In this article, we experienced a case of an elongated styloid process which is very rare in size and detailed treatment process. The patient was a 53-year-old Chinese woman with a chief complaint of frequent episodes of radiating pain in left preauricular region for 2 years. An intraoral approach was chosen to shorten part of her styloid process, and the chief complaint disappeared immediately after the operation...
2017: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/28835738/is-outpatient-thyroid-surgery-for-everyone
#16
REVIEW
Dale Butler, Sarah Oltmann
Thyroidectomy is a common surgical procedure. Traditionally, surgeons have performed thyroidectomy on an inpatient basis. However, consistent with current trends in surgery, some practices are transitioning thyroidectomy to an outpatient setting. Although concerns for hypocalcemia and postoperative bleeding exist regardless of surgeon experience, multiple studies demonstrate that outpatient thyroidectomy is safe in the hands of high-volume surgeons. Indeed, experienced thyroid surgeons who perform thyroidectomy in an outpatient setting experience excellent patient outcomes and reduced costs...
2017: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/28757800/case-report-recurrent-mucoepidermoid-carcinoma-of-the-tongue-in-adult-female-patient-with-lung-cancer
#17
Arielle Rubin, John Davis, Karim Jreije, Henry Wu, Randy Oppenheimer
There is a steady rise in incidence of malignant salivary gland tumors in the United States, with mucoepidermoid carcinoma (MEC) the most frequent. Although 40% of MECs are found in the parotid gland, these lesions possess the capacity to develop anywhere along the aerodigestive tract. Here, we present a case of recurrent tongue MEC in a young adult female patient with history of lung malignancy and multiple brain metastases. Without a universally accepted management protocol for recurrent MECs, the current clinical practice uses tumor grade, location, and clinical progression to determine both prognosis and goals of care...
2017: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/27773997/electronic-cigarette-role-in-the-primary-prevention-of-oral-cavity-cancer
#18
Teresa Franco, Serena Trapasso, Lidia Puzzo, Eugenia Allegra
BACKGROUND: Cigarette smoke has been identified as the main cause of oral cavity carcinoma. Recently, the electronic cigarette, a battery-operated device, was developed to help smokers stop their tobacco addiction. This study aimed to evaluate the safety of electronic cigarettes and to establish the possible role of such device in the primary prevention of oral cavity cancer. SUBJECTS AND METHODS: This study included 65 subjects who were divided into three groups (smokers, e-cigarette smokers, and nonsmokers)...
2016: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/27721662/a-novel-digital-patient-reported-outcome-platform-for-head-and-neck-oncology-patients-a-pilot-study
#19
Maria K Peltola, Joel S Lehikoinen, Lauri T Sippola, Kauko Saarilahti, Antti A Mäkitie
INTRODUCTION: The patient's role in toxicity reporting is increasingly acknowledged. There is also a need for developing modern communication methods between the patient and the medical personnel. Furthermore, the increasing number of head and neck cancer (HNC) patients is reflected in the volume of treatment follow-up visits, which remains a challenge for the health care. Electronic patient-reported outcome (ePRO) measures may provide a cost-efficient way to organize follow-up for cancer patients...
2016: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/26124693/the-relationship-between-stapes-prosthesis-length-and-rate-of-stapedectomy-success
#20
Cinzia L Marchica, Issam Saliba
OBJECTIVES: To identify whether measurement of the prosthesis length is mandatory in patients requiring otosclerosis surgeries and to assess their postoperative audiometric outcomes. In addition, evaluation of prosthesis length used in revision compared to primary stapedectomy was carried out. STUDY DESIGN: Case series with chart review. METHODS: Chart review of 393 patients undergoing primary (321) versus revision stapedectomy (72) was performed in a tertiary referral center...
2015: Clinical Medicine Insights. Ear, Nose and Throat
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