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Lancet Respiratory Medicine

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https://www.readbyqxmd.com/read/28215502/the-uncertain-science-of-predicting-tuberculosis
#1
Toyin Togun, Madhukar Pai
No abstract text is available yet for this article.
February 16, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28215501/serial-quantiferon-testing-and-tuberculosis-disease-risk-among-young-children-an-observational-cohort-study
#2
Jason R Andrews, Elisa Nemes, Michele Tameris, Bernard S Landry, Hassan Mahomed, J Bruce McClain, Helen A Fletcher, Willem A Hanekom, Robin Wood, Helen McShane, Thomas J Scriba, Mark Hatherill
BACKGROUND: The value of quantitative interferon-γ release assay results for predicting progression from Mycobacterium tuberculosis infection to active disease is unknown. We aimed to investigate the relation between QuantiFERON-TB Gold In-Tube (QFT) conversion interferon-γ values and risk of subsequent active tuberculosis disease and of QFT reversion. METHODS: We analysed data from a reported vaccine efficacy trial of the tuberculosis vaccine MVA85A in South Africa...
February 16, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28215638/libby-the-long-legacy-of-a-public-health-disaster
#3
Aaron van Dorn
No abstract text is available yet for this article.
February 15, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28219615/the-path-to-smoking-cessation-in-the-usa
#4
Aaron van Dorn
No abstract text is available yet for this article.
February 14, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28219614/palivizumab-prophylaxis-in-preterm-infants
#5
Paul Kiet Tang
No abstract text is available yet for this article.
February 14, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28219613/no-room-for-hyperoxia-or-hypertonic-saline-in-septic-shock
#6
Jean-Louis Vincent
No abstract text is available yet for this article.
February 14, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28219612/hyperoxia-and-hypertonic-saline-in-patients-with-septic-shock-hypers2s-a-two-by-two-factorial-multicentre-randomised-clinical-trial
#7
Pierre Asfar, Frédérique Schortgen, Julie Boisramé-Helms, Julien Charpentier, Emmanuel Guérot, Bruno Megarbane, David Grimaldi, Fabien Grelon, Nadia Anguel, Sigismond Lasocki, Matthieu Henry-Lagarrigue, Frédéric Gonzalez, François Legay, Christophe Guitton, Maleka Schenck, Jean Marc Doise, Jérôme Devaquet, Thierry Van Der Linden, Delphine Chatellier, Jean Philippe Rigaud, Jean Dellamonica, Fabienne Tamion, Ferhat Meziani, Alain Mercat, Didier Dreyfuss, Valérie Seegers, Peter Radermacher
BACKGROUND: There is insufficient research into the use of mechanical ventilation with increased inspiratory oxygen concentration (FiO2) and fluid resuscitation with hypertonic saline solution in patients with septic shock. We tested whether these interventions are associated with reduced mortality. METHODS: This two-by-two factorial, multicentre, randomised, clinical trial (HYPERS2S) recruited patients aged 18 years and older with septic shock who were on mechanical ventilation from 22 centres in France...
February 14, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28189522/effectiveness-of-seasonal-influenza-vaccination-in-community-dwelling-elderly-people-an-individual-participant-data-meta-analysis-of-test-negative-design-case-control-studies
#8
Maryam Darvishian, Edwin R van den Heuvel, Ange Bissielo, Jesus Castilla, Cheryl Cohen, Helene Englund, Giedre Gefenaite, Wan-Ting Huang, Sacha la Bastide-van Gemert, Iván Martinez-Baz, Johanna M McAnerney, Genevie M Ntshoe, Motoi Suzuki, Nikki Turner, Eelko Hak
BACKGROUND: Several aggregate data meta-analyses have provided estimates of the effectiveness of influenza vaccination in community-dwelling elderly people. However, these studies ignored the effects of patient-level confounders such as sex, age, and chronic diseases that could bias effectiveness estimates. We aimed to assess the confounder-adjusted effectiveness of influenza vaccines on laboratory-confirmed influenza among elderly people by conducting a global individual participant data meta-analysis...
February 8, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28189521/influenza-vaccine-effectiveness-using-the-test-negative-design-comparability-and-methodological-challenges-in-meta-analyses
#9
James E Fielding
No abstract text is available yet for this article.
February 8, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28169199/landmark-legal-ruling-sees-indian-girl-prescribed-bedaquiline-for-xdr-tb
#10
Tony Kirby
No abstract text is available yet for this article.
February 3, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28169198/lung-cancer-survival-only-increases-by-a-small-amount-despite-recent-treatment-advances
#11
Sanjeet Bagcchi
No abstract text is available yet for this article.
February 3, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28163021/calling-the-shots
#12
EDITORIAL
The Lancet Respiratory Medicine
No abstract text is available yet for this article.
February 2, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28163020/london-s-air-quality-crisis-reaches-new-heights
#13
Talha Khan Burki
No abstract text is available yet for this article.
February 2, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28161215/a-third-of-patients-diagnosed-with-asthma-have-no-current-symptoms-lending-support-to-guideline-recommendations
#14
Aaron van Dorn
No abstract text is available yet for this article.
February 1, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28159608/safety-and-efficacy-of-the-c-tb-skin-test-to-diagnose-mycobacterium-tuberculosis-infection-compared-with-an-interferon-%C3%AE-release-assay-and-the-tuberculin-skin-test-a-phase-3-double-blind-randomised-controlled-trial
#15
Morten Ruhwald, Henrik Aggerbeck, Rafael Vázquez Gallardo, Søren T Hoff, José I Villate, Bettine Borregaard, José A Martinez, Ingrid Kromann, Antón Penas, Luis L Anibarro, Maria Luiza de Souza-Galvão, Francisca Sánchez, Jose Ángel Rodrigo-Pendás, Antoni Noguera-Julian, Xavier Martínez-Lacasa, Maria Victoria Tuñez, Virginia Leiro Fernández, Joan P Millet, Antonio Moreno, Nazaret Cobos, José M Miró, Llanos Roldan, Angels Orcau, Peter Andersen, Joan A Caylá
BACKGROUND: Targeted screening and treatment of Mycobacterium tuberculosis infection substantially reduces the risk of developing active tuberculosis. C-Tb (Statens Serum Institute, Copenhagen, Denmark) is a novel specific skin test based on ESAT-6 and CFP10 antigens. We investigated the safety and diagnostic potential of C-Tb compared with established tests in the contact-tracing setting. METHODS: Negative controls, close contacts, occasional contacts, and patients with active pulmonary tuberculosis were enrolled at 13 centres in Spain...
January 31, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28159607/c-tb-a-latent-tuberculosis-skin-test-for-the-21st-century
#16
Ibrahim Abubakar, Charlotte Jackson, Molebogeng X Rangaka
No abstract text is available yet for this article.
January 31, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28109869/outcomes-infectiousness-and-transmission-dynamics-of-patients-with-extensively-drug-resistant-tuberculosis-and-home-discharged-patients-with-programmatically-incurable-tuberculosis-a-prospective-cohort-study
#17
Keertan Dheda, Jason D Limberis, Elize Pietersen, Jody Phelan, Aliasgar Esmail, Maia Lesosky, Kevin P Fennelly, Julian Te Riele, Barbara Mastrapa, Elizabeth M Streicher, Tania Dolby, Abdallah M Abdallah, Fathia Ben-Rached, John Simpson, Liezel Smith, Tawanda Gumbo, Paul van Helden, Frederick A Sirgel, Ruth McNerney, Grant Theron, Arnab Pain, Taane G Clark, Robin M Warren
BACKGROUND: The emergence of programmatically incurable tuberculosis threatens to destabilise control efforts. The aim of this study was to collect prospective patient-level data to inform treatment and containment strategies. METHODS: In a prospective cohort study, 273 South African patients with extensively drug-resistant tuberculosis, or resistance beyond extensively drug-resistant tuberculosis, were followed up over a period of 6 years. Transmission dynamics, infectiousness, and drug susceptibility were analysed in a subset of patients from the Western Cape using whole-genome sequencing (WGS; n=149), a cough aerosol sampling system (CASS; n=26), and phenotypic testing for 18 drugs (n=179)...
January 18, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28109868/management-of-extensively-drug-resistant-tuberculosis
#18
Rosella Centis, Giovanni Sotgiu, Giovanni Battista Migliori
No abstract text is available yet for this article.
January 18, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28089118/occupational-lung-diseases-from-old-and-novel-exposures-to-effective-preventive-strategies
#19
REVIEW
Paul Cullinan, Xavier Muñoz, Hille Suojalehto, Raymond Agius, Surinder Jindal, Torben Sigsgaard, Anders Blomberg, Denis Charpin, Isabella Annesi-Maesano, Mridu Gulati, Yangho Kim, Arthur L Frank, Metin Akgün, David Fishwick, Rafael E de la Hoz, Subhabrata Moitra
Occupational exposure is an important, global cause of respiratory disease. Unlike many other non-communicable lung diseases, the proximal causes of many occupational lung diseases are well understood and they should be amenable to control with use of established and effective approaches. Therefore, the risks arising from exposure to silica and asbestos are well known, as are the means of their prevention. Although the incidence of occupational lung disease has decreased in many countries, in parts of the world undergoing rapid economic transition and population growth-often with large informal and unregulated workforces-occupational exposures continue to impose a heavy burden of disease...
January 6, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28089117/respiratory-diseases-in-the-marginal-labour-sectors-a-call-to-action
#20
Subhabrata Moitra, Jesper Bælum, Nicola Murgia
No abstract text is available yet for this article.
January 6, 2017: Lancet Respiratory Medicine
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