Jiaxin Cai, Yang Li, Baichen Liu, Zhixi Wu, Shengjun Zhu, Qiliang Chen, Qing Lei, Hongyan Hou, Zhibin Guo, Hewei Jiang, Shujuan Guo, Feng Wang, Shengjing Huang, Shunzhi Zhu, Xionglin Fan, Shengce Tao
OBJECTIVE: The clinical course of COVID-19, as well as the immunological reaction, is notable for its extreme variability. Identifying the main associated factors might help understand the disease progression and physiological status of COVID-19 patients. The dynamic changes of the antibody against Spike protein are crucial for understanding the immune response. This work explores a temporal attention (TA) mechanism of deep learning to predict COVID-19 disease severity, clinical outcomes, and Spike antibody levels by screening serological indicators over time...
April 2, 2024: IEEE Journal of Biomedical and Health Informatics