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Journal of Stroke

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https://www.readbyqxmd.com/read/28592785/multidisciplinary-approach-to-decrease-in-hospital-delay-for-stroke-thrombolysis
#1
Sang-Beom Jeon, Seung Mok Ryoo, Deok Hee Lee, Sun U Kwon, Seongsoo Jang, Eun-Jae Lee, Sang Hun Lee, Jung Hee Han, Mi Jeong Yoon, Soo Jeong, Young-Uk Cho, Sungyang Jo, Seung-Bok Lim, Joong-Goo Kim, Han-Bin Lee, Seung Chai Jung, Kye Won Park, Min-Hwan Lee, Dong-Wha Kang, Dae Chul Suh, Jong S Kim
BACKGROUND AND PURPOSE: Decreasing the time delay for thrombolysis, including intravenous thrombolysis (IVT) with tissue plasminogen activator and intra-arterial thrombectomy (IAT), is critical for decreasing the morbidity and mortality of patients experiencing acute stroke. We aimed to decrease the in-hospital delay for both IVT and IAT through a multidisciplinary approach that is feasible 24 h/day. METHODS: We implemented the Stroke Alert Team (SAT) on May 2, 2016, which introduced hospital-initiated ambulance prenotification and reorganized in-hospital processes...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28592784/nationwide-hospital-emergent-capability-accreditation-by-level-stroke-improves-stroke-treatment-in-taiwan
#2
Tain-Junn Cheng, Giia-Sheun Peng, Wei-Siang Jhao, Jiunn-Tay Lee, Tsung-Hsi Wang
BACKGROUND AND PURPOSE: Recombinant tissue plasminogen activator (rtPA) is one of the proven therapies that improve the outcome of patients with acute ischemic stroke (AIS). In 2009, the Ministry of Health and Welfare, Executive Yuan, Republic of China, launched the project "Hospital Emergent Capability Accreditation by Level-Stroke (HECAL-Stroke)" to improve AIS treatment in Taiwan. The current study was performed to determine whether the project launched by the government was effective in promoting rtPA therapy among AIS patients...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28592783/association-of-optimal-combination-drug-treatment-with-obesity-status-among-recent-ischemic-stroke-patients-results-of-the-vitamin-intervention-for-stroke-prevention-visp-trial
#3
Jong-Ho Park, Juneyoung Lee, Bruce Ovbiagele
BACKGROUND AND PURPOSE: One explanation for the 'obesity paradox', where obese patients seem to have better cardiovascular outcomes than lean patients, is that obese patients display an identifiable high cardiovascular risk phenotype that may lead to receiving or seeking earlier/more aggressive treatment. METHODS: We analyzed a clinical trial dataset comprising 3643 recent (<120 days) ischemic stroke patients followed up for 2 years. Subjects were categorized as lean (body mass index [BMI], <25 kg/m(2), n=1,006), overweight (25-29...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28592782/family-history-and-stroke-risk-in-china-evidence-from-a-large-cohort-study
#4
Tian Tian, Guangfu Jin, Canqing Yu, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Hongbing Shen, Zhengming Chen, Zhibin Hu, Liming Li
BACKGROUND AND PURPOSE: Large cohort studies on relationship between family history of stroke (FHS) and stroke risk are lacking in Asians. We aimed to systematically evaluate the association of FHS with stroke risk in a cohort study of 0.5 million Chinese adults. METHODS: Information about FHS was self-reported. The median follow-up time was 7.16 years and the end-point of follow-up was incident stroke, which was entered directly into the China Kadoorie Biobank system...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28592781/endovascular-therapy-the-second-round-begins
#5
Jin Soo Lee, Keun-Sik Hong
No abstract text is available yet for this article.
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28592780/response-to-letter-by-dr-cristina-brandolini
#6
Hyun-Ah Kim, Hyung Lee
No abstract text is available yet for this article.
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28592779/thrombectomy-in-acute-ischemic-stroke-challenges-to-procedural-success
#7
REVIEW
Albert J Yoo, Tommy Andersson
The overwhelming clinical benefit of intra-arterial stroke therapy owes to the major advance in revascularization brought on by the current generation of thrombectomy devices. Nevertheless, there remains a sizeable proportion of patients for whom substantial reperfusion cannot be achieved or is achieved too late. This article addresses the persistent challenges that face neurointerventionists and reviews technical refinements that may help to mitigate these obstacles to procedural success. Insights from in vitro modeling and clinical research are organized around a conceptual framework that examines the interaction between the device, the thrombus and the vessel wall...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28592778/diagnostic-and-therapeutic-strategies-for-acute-intracranial-atherosclerosis-related-occlusions
#8
REVIEW
Jin Soo Lee, Ji Man Hong, Jong S Kim
Intracranial atherosclerosis-related occlusion (ICAS-O) is frequently encountered at the time of endovascular revascularization treatment (ERT), especially in Asian countries. However, because baseline angiographic findings are similar between ICAS-O and embolism-related occlusion (EMB-O), it is difficult to differentiate the etiologies before the ERT procedure. Moreover, despite successful randomized trials on ERT, results from studies examining the optimal treatment protocol in ICAS-O patients remain unclear...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28592777/causes-and-solutions-of-endovascular-treatment-failure
#9
REVIEW
Byung Moon Kim
In a meta-analysis of individual patient data from 5 randomized controlled trials, endovascular treatment (EVT) mainly using a stent retriever achieved successful recanalization in 71.1% of patients suffering from acute stroke due to anterior circulation large artery occlusion (LAO). However, EVT still failed in 28.9% of LAO cases in those 5 successful trials. Stent retriever failure may occur due to anatomical challenges (e.g., a tortuous arterial tree from the aortic arch to a target occlusion site), a large quantity of clots, tandem occlusion, clot characteristics (fresh versus organized clots), different pathomechanisms (embolic versus non-embolic occlusion), etc...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28592776/audiovestibular-loss-of-a-vascular-cause-a-distinction-should-be-made-between-cochlear-and-vestibular-symptoms
#10
Antonio Pirodda, Maria Chiara Raimondi, Cristina Brandolini
No abstract text is available yet for this article.
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28592775/blood-pressure-management-for-stroke-prevention-and-in-acute-stroke
#11
REVIEW
Keun-Sik Hong
Elevated blood pressure (BP) is the leading modifiable risk factor for stroke and the benefit of BP lowering therapy on the stroke risk reduction is well established. The optimal BP target for preventing stroke and other vascular events have been controversial, but the evidences from epidemiological studies and randomized controlled trials (RCTs) support intensive BP lowering for greater vascular protection, particularly for stroke prevention. For secondary stroke prevention, the evidence of intensive BP lowering benefit is limited since only a single RCT for patients with lacunar infarctions was conducted and most data were driven by exploratory analyses...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28480877/emerging-roles-of-micrornas-in-ischemic-stroke-as-possible-therapeutic-agents
#12
REVIEW
Seyed Esmaeil Khoshnam, William Winlow, Yaghoob Farbood, Hadi Fathi Moghaddam, Maryam Farzaneh
Stroke is one of the leading causes of death and physical disability worldwide. The consequences of stroke injuries are profound and persistent, causing in considerable burden to both the individual patient and society. Current treatments for ischemic stroke injuries have proved inadequate, partly owing to an incomplete understanding of the cellular and molecular changes that occur following ischemic stroke. MicroRNAs (miRNA) are endogenously expressed RNA molecules that function to inhibit mRNA translation and have key roles in the pathophysiological processes contributing to ischemic stroke injuries...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28460496/blood-pressure-may-be-associated-with-arterial-collateralization-in-anterior-circulation-ischemic-stroke-before-acute-reperfusion-therapy
#13
Beisi Jiang, Leonid Churilov, Lasheta Kanesan, Richard Dowling, Peter Mitchell, Qiang Dong, Stephen Davis, Bernard Yan
BACKGROUND AND PURPOSE: Leptomeningeal collaterals maintain arterial perfusion in acute arterial occlusion but may fluctuate subject to arterial blood pressure (ABP). We aim to investigate the relationship between ABP and collaterals as assessed by computer tomography (CT) perfusion in acute ischemic stroke. METHODS: We retrospectively analyzed acute anterior circulation ischemic stroke patients with CT perfusion from 2009 to 2014. Collateral status using relative filling time delay (rFTD) determined by time delay of collateral-derived contrast opacification within the Sylvian fissure, from 0 seconds to unlimited count...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28460495/acute-ischemic-stroke-in-nonconvulsive-status-epilepticus-underestimated-results-from-an-eight-year-cohort-study
#14
Christopher Traenka, Gian Marco De Marchis, Lisa Hert, David J Seiffge, Alexandros Polymeris, Nils Peters, Leo H Bonati, Stefan Engelter, Philippe Lyrer, Stephan Rüegg, Raoul Sutter
No abstract text is available yet for this article.
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28460494/how-to-identify-patients-at-risk-of-silent-atrial-fibrillation-after-cryptogenic-stroke-potential-role-of-p-wave-dispersion
#15
Maurizio Acampa, Pietro Enea Lazzerini, Giuseppe Martini
No abstract text is available yet for this article.
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28460493/simple-estimates-of-symptomatic-intracranial-hemorrhage-risk-and-outcome-after-intravenous-thrombolysis-using-age-and-stroke-severity
#16
Hye Jung Lee, Ji Sung Lee, Jay Chol Choi, Yong-Jin Cho, Beom Joon Kim, Hee-Joon Bae, Dong-Eog Kim, Wi-Sun Ryu, Jae-Kwan Cha, Dae Hyun Kim, Hyun-Wook Nah, Kang-Ho Choi, Joon-Tae Kim, Man-Seok Park, Jeong-Ho Hong, Sung Il Sohn, Kyusik Kang, Jong-Moo Park, Wook-Joo Kim, Jun Lee, Dong-Ick Shin, Min-Ju Yeo, Kyung Bok Lee, Jae Guk Kim, Soo Joo Lee, Byung-Chul Lee, Mi Sun Oh, Kyung-Ho Yu, Tai Hwan Park, Juneyoung Lee, Keun-Sik Hong
No abstract text is available yet for this article.
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28460492/factors-influencing-oral-anticoagulant-prescribing-practices-for-atrial-fibrillation
#17
Lester Y Leung, Mark McAllister, Magdy Selim, Marc Fisher
No abstract text is available yet for this article.
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178414/isolated-medullary-hemorrhage-clinical-features-in-eleven-consecutive-patients
#18
Sun-Uk Lee, Hyo-Jung Kim, Bong-Su Kang, Ji-Soo Kim
No abstract text is available yet for this article.
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178413/spontaneous-intracerebral-hemorrhage-management
#19
REVIEW
Jun Yup Kim, Hee-Joon Bae
Spontaneous non-traumatic intracerebral hemorrhage (ICH) remains a significant cause of mortality and morbidity throughout the world. To improve the devastating course of ICH, various clinical trials for medical and surgical interventions have been conducted in the last 10 years. Recent large-scale clinical trials have reported that early intensive blood pressure reduction can be a safe and feasible strategy for ICH, and have suggested a safe target range for systolic blood pressure. While new medical therapies associated with warfarin and non-vitamin K antagonist oral anticoagulants have been developed to treat ICH, recent trials have not been able to demonstrate the overall beneficial effects of surgical intervention on mortality and functional outcomes...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178412/carotid-wall-imaging-with-routine-brain-mri-to-facilitate-early-detection-of-carotid-plaque-and-intraplaque-hemorrhage
#20
Hyo Sung Kwak, Hye Jin Yang, Seung Bae Hwang, Gyung Ho Chung
No abstract text is available yet for this article.
January 2017: Journal of Stroke
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