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Journal of Stroke

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https://www.readbyqxmd.com/read/27733033/journal-of-stroke-jos-receives-high-impact-factor
#1
Jong S Kim
No abstract text is available yet for this article.
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733032/adult-stem-cell-therapy-for-stroke-challenges-and-progress
#2
Oh Young Bang, Eun Hee Kim, Jae Min Cha, Gyeong Joon Moon
Stroke is one of the leading causes of death and physical disability among adults. It has been 15 years since clinical trials of stem cell therapy in patients with stroke have been conducted using adult stem cells like mesenchymal stem cells and bone marrow mononuclear cells. Results of randomized controlled trials showed that adult stem cell therapy was safe but its efficacy was modest, underscoring the need for new stem cell therapy strategies. The primary limitations of current stem cell therapies include (a) the limited source of engraftable stem cells, (b) the presence of optimal time window for stem cell therapies, (c) inherited limitation of stem cells in terms of growth, trophic support, and differentiation potential, and (d) possible transplanted cell-mediated adverse effects, such as tumor formation...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733031/post-stroke-mood-and-emotional-disturbances-pharmacological-therapy-based-on-mechanisms
#3
Jong S Kim
Post-stroke mood and emotional disturbances are frequent and diverse in their manifestations. Out of the many post-stroke disturbances, post-stroke depression, post-stroke anxiety, post-stroke emotional incontinence, post-stroke anger proneness, and post-stroke fatigue are frequent and important symptoms. These symptoms are distressing for both the patients and their caregivers, and negatively influence the patient's quality of life. Unfortunately, these emotional disturbances are not apparent and are therefore often unnoticed by busy clinicians...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733030/herbs-and-rehabilitation-after-stroke-study-a-multi-center-double-blinded-randomized-trial-in-hong-kong
#4
Raymond Cheung, Li Xiong, Shek Kwan Chang, Choi Ting Tse, Yin Yu Pang, Vincent Mok, Thomas Leung, Tak Hong Tsoi, Richard Li, May Mok, Chee My Chang, Kwok Kwong Lau, Bun Sheng, Terrence Li, Jonas Yeung, Ping Chung Leung, Ping Chook, Ka Sing Wong
No abstract text is available yet for this article.
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733029/direct-thrombus-imaging-in-stroke
#5
Jongseong Kim, Jung E Park, Matthias Nahrendorf, Dong-Eog Kim
There is an emergent need for imaging methods to better triage patients with acute stroke for tissue-plasminogen activator (tPA)-mediated thrombolysis or endovascular clot retrieval by directly visualizing the size and distribution of cerebral thromboemboli. Currently, magnetic resonance (MR) or computed tomography (CT) angiography visualizes the obstruction of blood flow within the vessel lumen rather than the thrombus itself. The present visualization method, which relies on observation of the dense artery sign (the appearance of cerebral thrombi on a non-enhanced CT), suffers from low sensitivity...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733028/traditional-risk-factors-for-stroke-in-east-asia
#6
Young Dae Kim, Yo Han Jung, Gustavo Saposnik
Stroke is one of the leading causes of death and morbidity worldwide. The occurrence of stroke is strongly dependent on well-known vascular risk factors. After rapid modernization, urbanization, and mechanization, East Asian countries have experienced growth in their aged populations, as well as changes in lifestyle and diet. This phenomenon has increased the prevalence of vascular risk factors among Asian populations, which are susceptible to developing cardiovascular risk factors. However, differing patterns of stroke risk factor profiles have been noted in East Asian countries over the past decades...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733027/difference-in-the-location-and-risk-factors-of-cerebral-microbleeds-according-to-ischemic-stroke-subtypes
#7
Bum Joon Kim, Youngshin Yoon, Hoyon Sohn, Dong-Wha Kang, Jong S Kim, Sun U Kwon
BACKGROUND AND PURPOSE: The location of cerebral microbleeds (CMBs) may differ according to ischemic stroke subtype, and the underlying pathomechanism may differ by their location. Here, we investigated the characteristics of CMBs according to various ischemic stroke subtypes to verify this issue. METHODS: Patients with acute ischemic stroke were consecutively included. The presence of CMBs was determined by gradient echo image sequence. The distribution of CMBs was classified as deep, lobar, or diffuse (both deep and lobar)...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733026/association-of-left-atrial-enlargement-with-cortical-infarction-in-subjects-with-patent-foramen-ovale
#8
Mi Ji Lee, Sung-Ji Park, Chang Hyo Yoon, Ji-Won Hwang, Sookyung Ryoo, Suk Jae Kim, Gyeong-Moon Kim, Chin-Sang Chung, Kwang Ho Lee, Oh Young Bang
BACKGROUND AND PURPOSE: Left atrial dysfunction has been reported in patients with patent foramen ovale (PFO). Here we investigated the role of left atrial dysfunction in the development of embolic stroke in patients with PFO. METHODS: We identified consecutive patients with embolic stroke of undetermined sources except for PFO (PFO+ESUS). Healthy subjects with PFO served as controls (PFO+control). A stratified analysis by 10-year age group and an age- and sex- matching analysis were performed to compare echocardiographic markers between groups...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733025/reduction-of-midline-shift-following-decompressive-hemicraniectomy-for-malignant-middle-cerebral-artery-infarction
#9
Sang-Beom Jeon, Sun U Kwon, Jung Cheol Park, Deok Hee Lee, Sung-Cheol Yun, Yeon-Jung Kim, Jae-Sung Ahn, Byung-Duk Kwun, Dong-Wha Kang, H Alex Choi, Kiwon Lee, Jong S Kim
BACKGROUND AND PURPOSE: Hemicraniectomy is a decompressive surgery used to remove a large bone flap to allow edematous brain tissue to bulge extracranially. However, early indicators of the decompressive effects of hemicraniectomy are unclear. We investigated whether reduction of midline shift following hemicraniectomy is associated with improved consciousness and survival in patients with malignant middle cerebral artery infarctions. METHODS: We studied 70 patients with malignant middle cerebral artery infarctions (MMI) who underwent hemicraniectomies...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733024/prestroke-antiplatelet-effect-on-symptomatic-intracranial-hemorrhage-and-functional-outcome-in-intravenous-thrombolysis
#10
Jay Chol Choi, Ji Sung Lee, Tai Hwan Park, Yong-Jin Cho, Jong-Moo Park, Kyusik Kang, Kyung Bok Lee, Soo Joo Lee, Jae Guk Kim, Jun Lee, Man-Seok Park, Kang-Ho Choi, Joon-Tae Kim, Kyung-Ho Yu, Byung-Chul Lee, Mi-Sun Oh, Jae-Kwan Cha, Dae-Hyun Kim, Hyun-Wook Nah, Dong-Eog Kim, Wi-Sun Ryu, Beom Joon Kim, Hee-Joon Bae, Wook-Joo Kim, Dong-Ick Shin, Min-Ju Yeo, Sung Il Sohn, Jeong-Ho Hong, Juneyoung Lee, Keun-Sik Hong
BACKGROUND AND PURPOSE: About 30%-40% of stroke patients are taking antiplatelet at the time of their strokes, which might increase the risk of symptomatic intracranial hemorrhage (SICH) with intravenous tissue plasminogen activator (IV-TPA) therapy. We aimed to assess the effect of prestroke antiplatelet on the SICH risk and functional outcome in Koreans treated with IV-TPA. METHODS: From a prospective stroke registry, we identified patients treated with IV-TPA between October 2009 and November 2014...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27488981/prevalence-and-characteristics-of-unruptured-cerebral-aneurysms-in-ischemic-stroke-patients
#11
Ji Hwa Kim, Sang Hyun Suh, Joonho Chung, Yeo-Jin Oh, Sung Jun Ahn, Kyung-Yul Lee
BACKGROUND AND PURPOSE: The prevalence of unruptured cerebral aneurysms (UCAs) in ischemic stroke patients is not clearly defined. This study aimed to measure the prevalence and characteristics of UCAs in patients with acute ischemic stroke (AIS) and to compare our findings with those of the general population. In addition, we investigated the factors associated with cerebral aneurysms in AIS patients. METHODS: We retrospectively reviewed the brain magnetic resonance angiography images of 955 patients with AIS and 2,118 controls who had received a brain magnetic resonance angiography as part of a health check-up...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27488980/association-between-aortic-atheroma-and-cerebral-small-vessel-disease-in-patients-with-ischemic-stroke
#12
Tae-Jin Song, Young Dae Kim, Joonsang Yoo, Jinkwon Kim, Hyuk-Jae Chang, Geu Ru Hong, Chi Young Shim, Dongbeom Song, Ji Hoe Heo, Hyo Suk Nam
BACKGROUND AND PURPOSE: Cerebral small vessel disease (SVDs) are related with large artery atherosclerosis. However, the association between aortic atheroma (AA) and cerebral small vessel disease has rarely been reported. This study evaluated the relationship between presence and burden of AAs and those of SVDs in patients with acute ischemic stroke. METHODS: We included 737 consecutive patients who underwent transesophageal echocardiography (TEE) and brain magnetic resonance imaging (MRI) for evaluation of acute stroke...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27488979/neural-stem-cells-and-ischemic-brain
#13
Zhenggang Zhang, Michael Chopp
Stroke activates neural stem cells in the ventricular-subventricular zone (V/SVZ) of the lateral ventricle, which increases neuroblasts and oligodendrocyte progenitor cells (OPCs). Within the ischemic brain, neural stem cells, neuroblasts and OPCs appear to actively communicate with cerebral endothelial cells and other brain parenchymal cells to mediate ischemic brain repair; however, stroke-induced neurogenesis unlikely plays any significant roles in neuronal replacement. In this mini-review, we will discuss recent findings how intercellular communications between stroke-induced neurogenesis and oligodendrogenesis and brain parenchymal cells could potentially facilitate brain repair processes...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27488978/extended-use-of-hypothermia-in-elderly-patients-with-malignant-cerebral-edema-as-an-alternative-to-hemicraniectomy
#14
Han-Yeong Jeong, Jun-Young Chang, Kyu Sun Yum, Jeong-Ho Hong, Jin-Heon Jeong, Min-Ju Yeo, Hee-Joon Bae, Moon-Ku Han, Kiwon Lee
BACKGROUND AND PURPOSE: The use of decompressive hemicraniectomy (DHC) for the treatment of malignant cerebral edema can decrease mortality rates. However, this benefit is not sufficient to justify its use in elderly patients. We investigated the effects of therapeutic hypothermia (TH) on safety, feasibility, and functional outcomes in elderly patients with malignant middle cerebral artery (MCA) infarcts. METHODS: Elderly patients 60 years of age and older with infarcts affecting more than two-thirds of the MCA territory were included...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27488977/imaging-predictors-for-atherosclerosis-related-intracranial-large-artery-occlusions-in-acute-anterior-circulation-stroke
#15
Hong Il Suh, Ji Man Hong, Kyu Sun Lee, Miran Han, Jin Wook Choi, Jong S Kim, Andrew M Demchuk, Jin Soo Lee
No abstract text is available yet for this article.
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27488976/multiple-embolic-infarction-due-to-a-primary-aortic-intimal-sarcoma
#16
Heejung Mo, Hyung-Min Kwon, Jae-Sung Choi, Seon Jae Ahn, Yong-Seok Lee
No abstract text is available yet for this article.
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27488975/overall-and-gender-specific-associations-between-c-reactive-protein-and-stroke-occurrence-a-cross-sectional-study-in-us
#17
Yang Peng, Bin Dong, Zhiqiang Wang
No abstract text is available yet for this article.
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27283284/decision-making-support-using-a-standardized-script-and-visual-decision-aid-to-reduce-door-to-needle-time-in-stroke
#18
Hye-Yeon Choi, Eun Hye Kim, Joonsang Yoo, Kijeong Lee, Dongbeom Song, Young Dae Kim, Han-Jin Cho, Hyo Suk Nam, Kyung Yul Lee, Hye Sun Lee, Ji Hoe Heo
No abstract text is available yet for this article.
May 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27283283/location-of-cerebral-microbleeds-may-predict-subsequent-stroke-after-transient-ischemic-attack
#19
Jae-Sung Lim, Hyung-Min Kwon, Young-Seok Lee
No abstract text is available yet for this article.
May 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27283282/transcranial-magnetic-stimulation-and-diffusion-tensor-tractography-for-evaluating-ambulation-after-stroke
#20
Bo-Ram Kim, Won-Jin Moon, Hyuntae Kim, Eunhwa Jung, Jongmin Lee
BACKGROUND AND PURPOSE: We aimed to investigate the usefulness of combining transcranial magnetic stimulation (TMS) and diffusion tensor tractography (DTT) to evaluate corticospinal tract (CST) integrity and subsequently predict ambulatory function after middle cerebral artery (MCA) stroke. METHODS: Forty-three patients with first MCA stroke underwent TMS and DTT to evaluate CST integrity. Patients were classified into four groups according to the presence of motor-evoked potentials (MEPs) obtained from the tibialis anterior muscle and CST integrity...
May 2016: Journal of Stroke
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