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Journal of Stroke

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https://www.readbyqxmd.com/read/28178414/isolated-medullary-hemorrhage-clinical-features-in-eleven-consecutive-patients
#1
Sun-Uk Lee, Hyo-Jung Kim, Bong-Su Kang, Ji-Soo Kim
No abstract text is available yet for this article.
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178413/spontaneous-intracerebral-hemorrhage-management
#2
REVIEW
Jun Yup Kim, Hee-Joon Bae
Spontaneous non-traumatic intracerebral hemorrhage (ICH) remains a significant cause of mortality and morbidity throughout the world. To improve the devastating course of ICH, various clinical trials for medical and surgical interventions have been conducted in the last 10 years. Recent large-scale clinical trials have reported that early intensive blood pressure reduction can be a safe and feasible strategy for ICH, and have suggested a safe target range for systolic blood pressure. While new medical therapies associated with warfarin and non-vitamin K antagonist oral anticoagulants have been developed to treat ICH, recent trials have not been able to demonstrate the overall beneficial effects of surgical intervention on mortality and functional outcomes...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178412/carotid-wall-imaging-with-routine-brain-mri-to-facilitate-early-detection-of-carotid-plaque-and-intraplaque-hemorrhage
#3
Hyo Sung Kwak, Hye Jin Yang, Seung Bae Hwang, Gyung Ho Chung
No abstract text is available yet for this article.
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178411/computed-tomography-based-thrombus-imaging-for-the-prediction-of-recanalization-after-reperfusion-therapy-in-stroke
#4
REVIEW
Ji Hoe Heo, Kyeonsub Kim, Joonsang Yoo, Young Dae Kim, Hyo Suk Nam, Eung Yeop Kim
The prediction of successful recanalization following thrombolytic or endovascular treatment may be helpful to determine the strategy of recanalization treatment in acute stroke. Thrombus can be detected using noncontrast computed tomography (CT) as a hyperdense artery sign or blooming artifact on a T2(*)-weighted gradient-recalled image. The detection of thrombus using CT depends on slice thickness. Thrombus burden can be determined in terms of the length, volume, and clot burden score. The thrombus size can be quantitatively measured on thin-section CT or CT angiography/magnetic resonance angiography...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178410/strategies-to-extend-thrombolytic-time-window-for-ischemic-stroke-treatment-an-unmet-clinical-need
#5
REVIEW
Ike Dela Peña, Cesar Borlongan, Guofang Shen, Willie Davis
To date, reperfusion with tissue plasminogen activator (tPA) remains the gold standard treatment for ischemic stroke. However, when tPA is given beyond 4.5 hours of stroke onset, deleterious effects of the drug ensue, especially, hemorrhagic transformation (HT), which causes the most significant morbidity and mortality in stroke patients. An important clinical problem at hand is to develop strategies that will enhance the therapeutic time window for tPA therapy and reduce the adverse effects (especially HT) of delayed tPA treatment...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178409/smartphone-applications-providing-information-about-stroke-are-we-missing-stroke-risk-computation-preventive-applications
#6
Melvyn Wb Zhang, Roger Cm Ho
No abstract text is available yet for this article.
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178408/epidemiology-risk-factors-and-clinical-features-of-intracerebral-hemorrhage-an-update
#7
REVIEW
Sang Joon An, Tae Jung Kim, Byung-Woo Yoon
Intracerebral hemorrhage (ICH) is the second most common subtype of stroke and a critical disease usually leading to severe disability or death. ICH is more common in Asians, advanced age, male sex, and low- and middle-income countries. The case fatality rate of ICH is high (40% at 1 month and 54% at 1 year), and only 12% to 39% of survivors can achieve long-term functional independence. Risk factors of ICH are hypertension, current smoking, excessive alcohol consumption, hypocholesterolemia, and drugs. Old age, male sex, Asian ethnicity, chronic kidney disease, cerebral amyloid angiopathy (CAA), and cerebral microbleeds (CMBs) increase the risk of ICH...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178407/predictive-factors-for-good-outcome-and-mortality-after-stent-retriever-thrombectomy-in-patients-with-acute-anterior-circulation-stroke
#8
Woong Yoon, Seul Kee Kim, Man Seok Park, Byung Hyun Baek, Yun Young Lee
BACKGROUND AND PURPOSE: Predictive factors associated with stent-retriever thrombectomy for patients with acute anterior circulation stroke remain to be elucidated. This study aimed to investigate clinical and procedural factors predictive of good outcome and mortality after stent-retriever thrombectomy in a large cohort of patients with acute anterior circulation stroke. METHODS: We analyzed clinical and procedural data in 335 patients with acute anterior circulation stroke treated with stent-retriever thrombectomy...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178406/haemorrhagic-transformation-after-ischaemic-stroke-in-patients-taking-non-vitamin-k-antagonist-oral-anticoagulants
#9
Jan C Purrucker, Kirsten Haas, Marcel Wolf, Timolaos Rizos, Shujah Khan, Peter Kraft, Sven Poli, Rainer Dziewas, Johannes Meyne, Frederick Palm, Sebastian Jander, Markus Möhlenbruch, Peter U Heuschmann, Roland Veltkamp
BACKGROUND AND PURPOSE: To evaluate the frequency and outcome of haemorrhagic transformation (HT) after ischaemic stroke in patients treated with non-vitamin K antagonist oral anticoagulants (NOACs). METHODS: Patients with stroke on treatment with a NOAC were prospectively enrolled in this multicentre observational study between February 2012 and 2015. Brain imaging at admission and follow-up imaging until day 7 were reviewed for HT. Functional outcome was assessed by the modified Rankin scale (mRS) before the index event, at discharge, and at 3-months...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178405/statin-and-ezetimibe-combination-therapy-decreases-mean-platelet-volume-compared-to-statin-monotherapy
#10
Jun-Beom Lee, Gyeong-Seon Kim, Han-Na Cho
No abstract text is available yet for this article.
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178404/intracerebral-hemorrhage-large-disease-burden-but-less-therapeutic-progress
#11
Dong-Wha Kang
No abstract text is available yet for this article.
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28178403/smartphone-applications-providing-information-about-stroke-are-we-missing-stroke-risk-computation-preventive-applications
#12
Amod Amritphale, Nupur Amritphale, Divyanshu Dubey
No abstract text is available yet for this article.
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28030895/imaging-of-intracranial-hemorrhage
#13
REVIEW
Jeremy J Heit, Michael Iv, Max Wintermark
Intracranial hemorrhage is common and is caused by diverse pathology, including trauma, hypertension, cerebral amyloid angiopathy, hemorrhagic conversion of ischemic infarction, cerebral aneurysms, cerebral arteriovenous malformations, dural arteriovenous fistula, vasculitis, and venous sinus thrombosis, among other causes. Neuroimaging is essential for the treating physician to identify the cause of hemorrhage and to understand the location and severity of hemorrhage, the risk of impending cerebral injury, and to guide often emergent patient treatment...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28030894/hypercoagulability-and-mortality-of-patients-with-stroke-and-active-cancer-the-oasis-cancer-study
#14
Mi Ji Lee, Jong-Won Chung, Myung-Ju Ahn, Seonwoo Kim, Jin Myoung Seok, Hye Min Jang, Gyeong-Moon Kim, Chin-Sang Chung, Kwang Ho Lee, Oh Young Bang
BACKGROUND AND PURPOSE: Patients with active cancer are at an increased risk for stroke. Hypercoagulability plays an important role in cancer-related stroke. We aimed to test whether 1) hypercoagulability is a predictor of survival, and 2) correction of the hypercoagulable state leads to better survival in patients with stroke and active cancer. METHODS: We recruited consecutive patients with acute ischemic stroke and active systemic cancer between January 2006 and July 2015...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28030893/recent-advances-in-understanding-audiovestibular-loss-of-a-vascular-cause
#15
REVIEW
Hyun-Ah Kim, Hyung Lee
Acute audiovestibular loss is characterized by abrupt onset of prolonged (lasting days) vertigo and hearing loss. Acute ischemic stroke in the distribution of the anterior inferior cerebellar artery (AICA) is known to be the leading cause of acute audiovestibular loss. So far, eight subgroups of AICA territory infarction have been identified according to the patterns of audiovestibular dysfunctions, among which the most common pattern is the combined loss of auditory and vestibular functions. Unlike inner ear dysfunction of a viral cause, which can commonly present as an isolated vestibular (i...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28030892/non-vitamin-k-oral-anticoagulants-in-stroke-patients-practical-issues
#16
Konark Malhotra, Monica Khunger, David S Liebeskind
No abstract text is available yet for this article.
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28030891/impact-of-slow-blood-filling-via-collaterals-on-infarct-growth-comparison-of-mismatch-and-collateral-status
#17
Jeong Pyo Son, Mi Ji Lee, Suk Jae Kim, Jong-Won Chung, Jihoon Cha, Gyeong-Moon Kim, Chin-Sang Chung, Kwang Ho Lee, Oh Young Bang
BACKGROUND AND PURPOSE: Perfusion-diffusion mismatch has been evaluated to determine whether the presence of a target mismatch helps to identify patients who respond favorably to recanalization therapies. We compared the impact on infarct growth of collateral status and the presence of a penumbra, using magnetic resonance perfusion (MRP) techniques. METHODS: Consecutive patients who were candidates for recanalization therapy and underwent serial diffusion-weighted imaging (DWI) and MRP were enrolled...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/27733033/journal-of-stroke-jos-receives-high-impact-factor
#18
Jong S Kim
No abstract text is available yet for this article.
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733032/adult-stem-cell-therapy-for-stroke-challenges-and-progress
#19
REVIEW
Oh Young Bang, Eun Hee Kim, Jae Min Cha, Gyeong Joon Moon
Stroke is one of the leading causes of death and physical disability among adults. It has been 15 years since clinical trials of stem cell therapy in patients with stroke have been conducted using adult stem cells like mesenchymal stem cells and bone marrow mononuclear cells. Results of randomized controlled trials showed that adult stem cell therapy was safe but its efficacy was modest, underscoring the need for new stem cell therapy strategies. The primary limitations of current stem cell therapies include (a) the limited source of engraftable stem cells, (b) the presence of optimal time window for stem cell therapies, (c) inherited limitation of stem cells in terms of growth, trophic support, and differentiation potential, and (d) possible transplanted cell-mediated adverse effects, such as tumor formation...
September 2016: Journal of Stroke
https://www.readbyqxmd.com/read/27733031/post-stroke-mood-and-emotional-disturbances-pharmacological-therapy-based-on-mechanisms
#20
REVIEW
Jong S Kim
Post-stroke mood and emotional disturbances are frequent and diverse in their manifestations. Out of the many post-stroke disturbances, post-stroke depression, post-stroke anxiety, post-stroke emotional incontinence, post-stroke anger proneness, and post-stroke fatigue are frequent and important symptoms. These symptoms are distressing for both the patients and their caregivers, and negatively influence the patient's quality of life. Unfortunately, these emotional disturbances are not apparent and are therefore often unnoticed by busy clinicians...
September 2016: Journal of Stroke
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