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Medical Mycology Case Reports

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https://www.readbyqxmd.com/read/29034160/eosinophilic-plasmacytic-conjunctivitis-concurrent-with-gingival-fistula-caused-by-schizophyllum-commune-in-a-captive-cheetah-acinonyx-jubatus
#1
Madoka Yoshizawa, Shinpei Kawarai, Yoshiko Torii, Kaori Ota, Kiyoshi Tasaka, Kazuko Nishimura, Chieko Fujii, Nobuyuki Kanemaki
We describe for the first time the diagnosis of Schizophyllum commune infection in a captive cheetah. Eosinophilic plasmacytic conjunctivitis was detected histopathologically in a biopsy specimen. Both a second surgical specimen and drainage fluid from a gingival mass and fistula contained fungal hyphae in giant cells with granulomatous inflammation. Allergic S. commune mycosis was suspected at this point. A monokaryotic isolate was characterized morphologically, and then identified genetically. Treatment with itraconazole and pimaricin was effective...
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28970974/pediatric-gastrointestinal-basidiobolomycosis-mimicking-malignancy
#2
Zainab Almoosa, Mohammed Alsuhaibani, Sadeq AlDandan, Dayel Alshahrani
Basidiobolomycosis is a rare fungal infection with high prevalence in southwestern province of Saudi Arabia (Tohama region); it mainly causes subcutaneous infections and rarely gastrointestinal disease. Because of its indolent presentation, it is often misdiagnosed as IBD, tuberculosis or Malignancy. We are reporting a 7 year old Saudi girl with abdominal mass, fever and eosinophilia resembling malignancy on radiological and pathological picture fully recovered with only medical therapy in the form of oral Voriconazole 2012 Elsevier Ltd...
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28808616/periprosthetic-hip-joint-infection-with-aspergillus-terreus-a-clinical-case-and-a-review-of-the-literature
#3
Rachel Bartash, Yi Guo, John B Pope, Michael H Levi, Wendy Szymczak, Nidhi Saraiya, Priya Nori
Fungal periprosthetic joint infections due to Aspergillus species are rare but are associated with significant cost and morbidity. We present a case of Asperigillus terreus prosthetic joint infection of the hip. The patient was successfully treated with a prolonged course of systemic antifungals along with surgical management.
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28794961/feline-cutaneous-histoplasmosis-the-first-case-report-from-thailand
#4
L Larsuprom, L Duangkaew, C Kasorndorkbua, C Chen, A Chindamporn, N Worasilchai
A 2-year-old, neutered female domestic shorthaired cat presented with a history of multiple papules and nodules on pinnae, nodules on the nose, and chronic wound at the lateral surface of left radial area for four months. Skin biopsy demonstrated moderate numbers of small, oval-to-round, single-walled yeasts inside the macrophages. In addition, PCR confirmed the sequence of Histoplasma capsulatum. This is the first case report of feline cutaneous histoplasmosis in Thailand.
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28794960/gastric-perforation-after-duodenopancreatectomy
#5
Henrik Bäcker, Frank Jp Beeres, Marco Rossi, Andreas Scheiwiller
Fungal and bacterial infections are often which may cause sepsis. Mucormycosis is an unfrequent, but often life-threatening disease. A timely diagnosis and treatment is the cornerstone of success. An increase in incidence can be expected, given an aging population and increasing incidence of obesity, diabetes and cancer. We present a rare case where early diagnosis has helped to treat the patient mainly with antifungal therapy as surgical therapy has had high risk of complications.
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28794959/cutaneous-lesions-due-to-trichosporon-jirovecii-in-a-tortoise-testudo-hermanni
#6
Simona Nardoni, Marco Salvadori, Alessandro Poli, Guido Rocchigiani, Francesca Mancianti
Cutaneous mycoses have been rarely reported in Chelonians. A Testudo hermanni adult male showed a thick erosion of the dorsal neck covered by necrotic material. Trichosporon sp. was cultivated, while arthrospores and hyphae were observed in histological sections. The causative agent was identified as Trichosporon jirovecii by PCR. After a surgical intervention povidone iodine and Iruxol® ointment were daily administered through the drainage for 2 weeks, along with enrofloxacin 5 mg diluted in saline 0.5 ml via the intracelomatic route...
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28794958/saccharomyces-cerevisiae-var-boulardii-fungemia-following-probiotic-treatment
#7
Marcelo C Appel-da-Silva, Gabriel A Narvaez, Leandro R R Perez, Laura Drehmer, Jairo Lewgoy
Probiotics are commonly prescribed as an adjuvant in the treatment of antibiotic-associated diarrhea caused by Clostridium difficile. We report the case of an immunocompromised 73-year-old patient on chemotherapy who developed Saccharomyces cerevisiae var. boulardii fungemia in a central venous catheter during treatment of antibiotic-associated pseudomembranous colitis with the probiotic Saccharomyces cerevisiae var. boulardii. Fungemia was resolved after interruption of probiotic administration without the need to replace the central venous line...
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28761803/invasive-aspergillosis-in-a-patient-with-end-stage-renal-disease
#8
Neslihan Cicek, Nurdan Yildiz, Eda Kepenekli Kadayifci, Ibrahim Gokce, Harika Alpay
Invasive aspergillosis caused by A. Fumigatus, almost occurs in immunocompromised hosts and has a poor prognosis. We report a case of invasive Aspergillosis in a 15-year-old boy with ESRD. He was initially diagnosed as lobar pneumonia and peritonitis. When he complained for lower extremity weakness and had convulsions, a solid mass originated from right lung compresses the spinal cord and intracranial hemorrhagic abscesses were found on MRI. The biopsy specimen showed hypae of aspergillus-spp and he died on 12th day...
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28761802/a-case-of-tinea-incognita-and-differential-diagnosis-of-figurate-erythema
#9
Julia-Tatjana Maul, Philipp W Maier, Florian Anzengruber, Carla Murer, Philipp P Bosshard, Katrin Kerl, Lars E French, Alexander A Navarini
A patient with tinea incognita is presented together with a review of the literature of figurate erythema. Figurate lesions are emblematic for dermatology and perhaps the most picturesque efflorescences. The differential diagnosis can be broad and sometimes challenging. Many clinical entities with resembling primary and secondary efflorescences have to be considered as differentials and can be due to anti-infectious, paraneoplastic, allergic, autoimmune or other immune reactions.
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28725545/a-severe-transmissible-majocchi-s-granuloma-in-an-immunocompetent-returned-traveler
#10
James G Gallo, Marion Woods, Rikki M Graham, Amy V Jennison
Severe dermatophyte infection is rare in immunocompetent adults. Recently cases have been described in travelers returning from South East Asia (Luchsinger et al., 2015) [1]. These may be sexually transmitted and can have permanent sequelae. We describe the first reported case of Majocchi's granuloma (MG) in an Australian returned traveler and its subsequent transmission via sexual contact. Both patients were successfully treated with systemic antifungals. MG should be considered in patients with severe rash after travel to South East Asia...
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28725544/successful-haploidentical-stem-cell-transplantation-with-prophylactic-administration-of-liposomal-amphotericin-b-after-invasive-pulmonary-zygomycosis
#11
Testuro Ochi, Yuta Katayama, Takeshi Okatani, Ryota Imanaka, Kohei Kyo, Mitsuhiro Itagaki, Shinya Katsutani, Koji Iwato, Hideki Asaoku
A 54-year-old woman with acute myeloid leukemia (AML) achieved complete remission by induction chemotherapy, but developed zygomycosis after consolidation therapy. As zygomycosis could not be cured by liposomal amphotericin B and micafungin, left lower lobectomy was performed. As AML relapsed 7 months after onset, she received haploidentical stem cell transplantation under administration of liposomal amphotericin B. Despite experiencing severe acute graft-versus-host disease, she remains alive with no relapse of either zygomycosis or AML...
December 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28702318/aspergillus-nodules-in-chronic-granulomatous-disease-attributable-to-aspergillus-ochraceus
#12
Samihah Moazam, David W Denning
Aspergillus ochraceus is a rare pulmonary pathogen. A 39 year old male with COPD and chronic granulomatous disease presented with severe breathlessness and recurrent infections. CT scan demonstrated multiple pulmonary nodules diagnosed as chronic pulmonary aspergillosis. The patient's sputum grew Aspergillus ochraceus thrice over 6 months, alongside positive Aspergillus IgG and serum galactomannan. Despite treatment with itraconazole, the patient continued to be symptomatic. We present the first case associating A...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28702317/fungal-keratitis-caused-by-metarhizium-anisopliae-complex
#13
Mahmood J Showail, Julianne V Kus, George Kar Tsui, Hall F Chew
PURPOSE: To report a case of fungal keratitis caused by Metarhizium anisopliae complex. METHODS: Case report. RESULTS: Our patient presented with a central corneal infiltrate. Fungal culture yielded a Metarhizium species. She was started on antifungal agents with no significant improvement. A therapeutic corneal transplant was performed after perforation. At two years follow up, she was free of infection. CONCLUSION: Metarhizium anisopliae is a very rare cause of keratitis...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28702316/sporotrichosis-in-a-liver-transplant-patient-a-case-report-and-literature-review
#14
Renato Ferreira da Silva, Miguel Bonfitto, Francisco Inaldo Mendes da Silva Junior, Margarete Teresa Gottardo de Ameida, Rita de Cma da Silva
The liver transplant patient was admitted to the hospital with hyperemic, granulomatous, ulcerated lesion in the anterior compartment of the right lower limb with report of local trauma. The agent Sporothrix schenckii was isolated from biopsy of the lesion and lymph nodes of the right lower limb. In this case, the treatment was difficult because the patient has severe pulmonary hypertension and took the following drugs: warfarin, sildenafil, and tacrolimus. These medicines interact with the antifungal, which made it difficult...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28664030/disseminated-nannizziopsis-obscura-infection-in-a-renal-transplant-patient-the-first-reported-case
#15
Amy Baggott, Hugh McGann, Richard Barton, Jennifer Ratner
This is a presentation of a case of disseminated fungal infection in a renal transplant patient with Nannizziopsis obscura, a species not previously reported as having caused disseminated disease in humans and not previously reported in the UK. The fungus was isolated from a intramuscular collection and from a lymph node. The patient responded well to a course of posaconazole.
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28649485/scedosporium-apiospermum-brain-abscesses-in-a-patient-after-near-drowning-a-case-report-with-10-year-follow-up-and-a-review-of-the-literature
#16
Sandra C Signore, Christoph P Dohm, Gunther Schütze, Mathias Bähr, Pawel Kermer
Scedosporium apiospermum is known to be a fungal pathogen affecting immunocompromised as well as non-immunodeficient patients. Although this fungus is found rarely, an infection can lead to severe and even fatal disease. Here, we describe the case of a 41-year-old female who developed multiple Scedosporium apiospermum brain abscesses after near-drowning with aspiration of contaminated mud and water. She showed various neurological symptoms. The patient recovered after removal of abscesses in combination with long-term antifungal treatment...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28626627/tonsillar-ulceration-as-manifestation-of-disseminated-african-histoplasmosis-in-an-immunocompetent-portuguese-host
#17
L Cardoso, C Silva, N Marques, C Veríssimo
Histoplasmosis is a systemic mycosis caused by Histoplasma capsulatum. Rare in Europe but endemic in some regions of Brazil, United States, Africa and Asia. Most of the cases are asymptomatic. Disseminated form is defined by the presence of an extra-pulmonary focus, particularly associated with immunosuppression. We report a case of an unilateral persisted tonsillar ulceration, in an immunocompetent Portuguese host, as manifestation of disseminated African histoplasmosis 45 years later after living 3 years in Africa...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28580237/combination-liposomal-amphotericin-b-posaconazole-and-oral-amphotericin-b-for-treatment-of-gastrointestinal-mucorales-in-an-immunocompromised-patient
#18
Anthony Anderson, Dayna McManus, Sarah Perreault, Ying-Chun Lo, Stuart Seropian, Jeffrey E Topal
Mucormycosis is a life threatening infection caused by fungi in the order Mucorales. Mucormycosis can affect any organ system with rhino-orbital-cerebral and pulmonary infections being the most predominant infection types. Gastrointestinal mucormycosis is rare and accounts for only 4-7% of all cases. Here, we present a case of invasive gastrointestinal mucormycosis in an immunocompromised host treated with systemic and topical anti-mold therapy.
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28580236/penicillium-citrinum-opportunistic-pathogen-or-idle-bystander-a-case-analysis-with-demonstration-of-galactomannan-cross-reactivity
#19
Shayla E Hesse, Paul M Luethy, John H Beigel, Adrian M Zelazny
We present a case of an immunocompromised woman with fever, pulmonary infiltrates and multiple bronchoalveolar lavage (BAL) cultures positive for Penicillium citrinum with a concomitant high BAL galactomannan level. We report the results of Aspergillus galactomannan testing performed on culture supernatants from her P. citrinum strain that confirmed the suspected cross-reactivity. Finally, we discuss the clinical significance and antifungal susceptibility of P. citrinum in our case and review the literature...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28560131/fatal-invasive-aspergillosis-caused-by-aspergillus-niger-after-bilateral-lung-transplantation
#20
Enora Atchade, Sylvain Jean-Baptiste, Sandrine Houzé, Claire Chabut, Laurent Massias, Yves Castier, Olivier Brugière, Hervé Mal, Philippe Montravers
Aspergillus niger is usually considered to be a low virulence fungus, not commonly reported to cause invasive infections. Invasive pulmonary aspergillosis due to Aspergillus niger was diagnosed in a 43-year-old woman following bilateral lung transplantation. Intravenous voriconazole failed to control progression of the disease. Despite salvage therapy with a combination of voriconazole and caspofungin for 23 days, the patient developed massive hemoptysis leading to death. The authors report the clinical features and treatment of this case...
September 2017: Medical Mycology Case Reports
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