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Iranian Journal of Neurology

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https://www.readbyqxmd.com/read/29736229/vertebral-artery-occlusion-after-anterior-cervical-discectomy-with-fusion
#1
Masatoshi Yunoki, Takahiro Kanda, Kenta Suzuki, Atsuhito Uneda, Koji Hirashita, Kimihiro Yoshino
No abstract text is available yet for this article.
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29736228/height-shape-and-anterior-posterior-diameter-of-pituitary-gland-on-magnetic-resonance-imaging-among-patients-with-multiple-sclerosis-compared-to-normal-individuals
#2
Mohammad Saba, Hossein Ali Ebrahimi, Habibeh Ahmadi-Pour, Mohammad Khodadoust
Background: Several studies indicate contribution of hypothalamus-pituitary-adrenal (HPA) axis in multiple sclerosis (MS) disease. This study was designed to determine whether there is an effective difference in pituitary height, shape, and anterior-posterior diameter (APD) between patients with MS and the control group. Methods: In this study, sagittal pituitary height and APD of 134 men and women (64 patients with MS and 70 healthy subjects as control group) were measured by T1 sequence magnetic resonance imaging (MRI)...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29736227/molecular-mechanisms-of-omega-3-fatty-acids-in-the-migraine-headache
#3
REVIEW
Neda Soveyd, Mina Abdolahi, Sama Bitarafan, Abbas Tafakhori, Payam Sarraf, Mansoureh Togha, Ali Asghar Okhovat, Mahsa Hatami, Mohsen Sedighiyan, Mahmoud Djalali, Niyaz Mohammadzadeh Honarvar
Migraine is a common chronic inflammatory neurological disease with the progressive and episodic course. Much evidence have shown a role of inflammation in the pathogenesis of migraine. Omega-3 fatty acids are an important components of cell membranes phospholipids. The intake of these fatty acids is related to decrease concentration of C-reactive protein (CRP), proinflammatory eicosanoids, cytokines, chemokines and other inflammation biomarkers. Many of clinical trials have shown the beneficial effect of dietary supplementation with omega-3 fatty acids in inflammatory and autoimmune diseases in human, including Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), multiple sclerosis (MS) and migraine headaches...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29736226/ten-year-trend-in-stroke-incidence-and-its-subtypes-in-isfahan-iran-during-2003-2013
#4
Ahmad Bahonar, Alireza Khosravi, Fariborz Khorvash, Mohammadreza Maracy, Shahram Oveisgharan, Noushin Mohammadifard, Mohammad Saadatnia, Fatemeh Nouri, Nizal Sarrafzadegan
Background: As there was no evidence of long-term studies on stroke trend, stroke subtypes and its relationships to stroke risk factors and demographic characteristics in Iran, we aimed to evaluate the 10-year trend of stroke incidence and stroke subtypes in Isfahan, Iran. Methods: In a hospital-based retrospective study, 24186 cases with the first-ever stroke were analyzed. We assessed the incidence trend of annual stroke and its subtypes [ischemic stroke (IS) subarachnoid hemorrhage (SAH), and intracranial hemorrhage (ICH)] during the years 2003 to 2013 by sex, and studied the association of demographic and major stroke risk factors with incidence and mortality rate of stroke...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29736225/molecular-changes-in-obese-and-depressive-patients-are-similar-to-neurodegenerative-disorders
#5
Laleh Habibi, Abbas Tafakhori, Rasoul Hadiani, Maryam Maserat-Mashhadi, Zeinab Kafrash, Shahla Torabi, Mohammad Azhdarzadeh, Seyed Mohammad Akrami, Morteza Mahmoudi, Rasoul Dinarvand
Background: Neurodegenerative disorders (NDs) are categorized as multifactorial conditions with different molecular and environmental causes. Disturbance of important signaling pathways, such as energy metabolism and inflammation induced by environmental agents, is involved in the pathophysiology of NDs. It has been proposed that changes in the lifestyle and nutrition (metabolism) during mid-life could trigger and accumulate cellular and molecular damages resulting in NDs during aging. Methods: In order to test the hypothesis, we investigated the expression level of two energy metabolism-related [forkhead box O1 (FOXO1) and forkhead box O3 (FOXO3A)] and two pro-inflammatory cytokines [interleukin 1β (IL-1β) and IL-6] genes, using quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR)...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29736224/prognostic-value-of-ictal-onset-patterns-in-postsurgical-outcome-of-temporal-lobe-epilepsy
#6
Jafar Mehvari-Habibabadi, Reza Basiratnia, Houshang Moein, Mohamad Zare, Majid Barakatain, Yahya Aghakhani, Nasim Tabrizi
Background: To investigate ictal onset patterns (IOP) in scalp electroencephalography (EEG) of patients with temporal lobe epilepsy (TLE) and their prognostic effect on the postoperative outcome. Methods: We conducted a retrospective cohort study between 2011 and 2015 in our referral Epilepsy Surgery Center enrolling adult patients with refractory TLE and a visible epileptogenic lesion in magnetic resonance imaging (MRI), who underwent epilepsy surgery. Demographic, clinical and MRI findings were collected and ictal findings during video-EEG monitoring were reviewed in detail...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29736223/the-effect-of-swallowing-rehabilitation-on-quality-of-life-of-the-dysphagic-patients-with-cortical-ischemic-stroke
#7
Kadir Bahcecı, Ebru Umay, Ibrahim Gundogdu, Eda Gurcay, Erhan Ozturk, Sibel Alıcura
Background: Swallowing and swallowing-related quality of life studies following stroke were almost always performed by including both patients with brainstem and cortical involvement. It was aimed in this study to show the presence of dysphagia in patients with only cortical ischemic stroke and to investigate the interaction between dysphagia and quality of life as well as to evaluate the effect of a rehabilitation program in the acute phase. Methods: Seventy-two patients with cortical stroke (between 0 and 30 days) and dysphagia were included...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29736222/analysis-of-apolipoprotein-e-genetic-variation-in-patients-with-alzheimer-disease-referred-to-imam-reza-clinic-rasht-iran-in-2015
#8
Amir Reza Ghayeghran, Maryam Akbarshahi, Zivar Salehi, Ali Davoudi-Kiakalayeh
Background: Alzheimer disease (AD) is a progressive neurological degenerative disorder and the most common form of dementia. There are about 100 genes linked to AD including apolipoprotein E (ApoE). This gene exists in the form of three allele polymorphisms of ε2 , ε3 and ε4 and six genotypes of ε2 ε3 , ε2 ε2 , ε3 ε3 , ε2 ε4 , ε3 ε4 , and ε4 ε4 . We aimed to study the association of ApoE polymorphism with AD in Guilan province, Iran. Methods: The study group consisted of 70 AD patients and 100 healthy individuals as a control group...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29736221/the-relationship-of-multiple-sclerosis-and-cerebral-developmental-venous-anomaly-with-an-advantageous-role-in-the-multiple-sclerosis-diagnosis
#9
Mohammad Reza Sasani, Ali Reza Dehghan, Nikseresht Ali Reza
Background: There is a suggestion for a role of abnormal cranial venous drainage in the etiopathogenesis of multiple sclerosis (MS). Moreover, it seems that cerebral developmental venous anomaly (DVA), a cerebrovascular malformation, is frequently seen in the magnetic resonance imaging (MRI) of MS patients. This study is set out to evaluate the relationship between MS and cerebral DVA, with its possible role in the MS diagnosis. Methods: We compared MRI of 172 MS patients and of 172 age- and sex-matched subjects without MS...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29736220/determination-of-cut-off-point-of-cross-sectional-area-of-median-nerve-at-the-wrist-for-diagnosing-carpal-tunnel-syndrome
#10
Majid Ghasemi, Sanaz Masoumi, Behnaz Ansari, Mahboobeh Fereidan-Esfahani, Seyed Morteza Mousavi
Background: The most common entrapment mononeuropathy of the upper extremity is carpal tunnel syndrome (CTS). It consists 90% of entrapment neuropathies. The purpose of this study was to compare cross-sectional area (CSA) of the median nerve at the wrist in CTS patients and healthy controls and define the best cut-off point of CSA to differentiate patients and controls in Iranian population. Methods: In this study, 45 patients with confirmed idiopathic CTS and 62 healthy controls were evaluated. Based on electrophysiological findings, patients were divided based on CTS severity into three groups of mild, moderate and severe...
October 7, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29114373/coiled-distal-internal-carotid-artery-ica-aneurysm-in-transcranial-sonography
#11
Masoud Mehrpour, Fahimeh Haji-Akhoundi, Babak Zamani
No abstract text is available yet for this article.
July 6, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29114372/churg-straus-syndrome-a-case-report
#12
Safa Najmi, Armaghan Ghareaghaji-Zare, Saeed Ghazanfari-Amlashi
No abstract text is available yet for this article.
July 6, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29114371/sarcoidosis-limbic-encephalitis-a-case-report
#13
Moussa Toudou-Daouda, Hamid Assadeck, Boubacar Efared
No abstract text is available yet for this article.
July 6, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29114370/taming-alzheimer-s-disease-new-perspectives-newer-horizons
#14
REVIEW
Debraj Sen, Anusree Majumder, Vijinder Arora, Neha Yadu, Ritwik Chakrabarti
Alzheimer's disease (AD) is the leading cause of dementia. However, current therapies do not prevent progression of the disease. New research into the pathogenesis of the disease has brought about a greater understanding of the "amyloid cascade" and associated receptor abnormalities, the role of genetic factors, and revealed that the disease process commences 10 to 20 years prior to the appearance of clinical signs. This greater understanding of the disease has prompted development of novel disease-modifying therapies (DMTs) which may prevent onset or delay progression of the disease...
July 6, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29114369/bimelic-symmetric-hirayama-disease-spectrum-of-magnetic-resonance-imaging-findings-and-comparative-evaluation-with-classical-monomelic-amyotrophy-and-other-motor-neuron-disease
#15
Deb Kumar Boruah, Shantiranjan Sanyal, Arjun Prakash, Sashidhar Achar, Dhabal D Dhingani, Binod Sarma
Background: The aim of the study was to evaluate the magnetic resonance imaging (MRI) findings in bilateral symmetrical Hirayama disease and find out MRI features which are probably more indicative of symmetrical Hirayama disease, thereby help in differentiating this entity from other motor neuron disease (MND). Methods: This prospective as well as retrospective study was carried out from December 2010 to September 2016 in a tertiary care center of northeast India on 92 patients with Hirayama disease. Only 19 patients having bilateral symmetric upper limb involvement at the time of presentation were included in this study sample...
July 6, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29114368/recurrent-isolated-optic-neuritis-a-study-on-22-patients
#16
Mahsa Arzani, Mohammad Ali Sahraian, Hamed Rezaei, Abdorreza Naser Moghadasi
Background: Isolated relapsing optic neuropathy is a recurrent painful optic nerve inflammation without any sign of other demyelinating diseases such as multiple sclerosis (MS) or neuromyelitis optica (NMO) spectrum disorders, and the attacks are purely responsive to steroid therapy. Methods: Recurrent isolated optic neuritis (RION) was diagnosed in patients who presented with at least two disseminating episodes of optic neuritis, and negative clinical, para-clinical, and radiological features of the demyelinating, infiltrative and vasculitis disorders involving optic nerve...
July 6, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29114367/the-comparison-of-anti-seizure-and-tocolytic-effects-of-phenytoin-and-magnesium-sulphate-in-the-treatment-of-eclampsia-and-preeclampsia-a-randomised-clinical-trial
#17
Maryam Khooshideh, Majid Ghaffarpour, Sama Bitarafan
Background: To date, magnesium sulphate (MgSO4 ) is the treatment of choice for prevention of seizure in eclampsia and preeclampsia. However, there are some limitations in the administration of MgSO4 due to its tocolytic effects. The aim of this study was to compare the anticonvulsant and tocolytic effects of MgSO4 and another drug, phenytoin, in patients with eclampsia and preeclampsia. Methods: This clinical trial was conducted on pregnant women hospitalised with eclampsia or preeclampsia, during 2014-2016...
July 6, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29114366/evaluation-of-non-motor-symptoms-and-their-impact-on-quality-of-life-in-patients-with-parkinson-s-disease-isfahan-iran
#18
Mehri Salari, Ahmad Chitsaz, Masoud Etemadifar, Mohammad Reza Najafi, Omid Mirmosayyeb, Maryam Bemanalizadeh, Fatemeh Panahi, Hosna Mirzajani
Background: Parkinson's disease (PD) is diagnosed on the basis of motor symptoms, but non-motor symptoms (NMS) have high prevalence in PD and often antecede motor symptoms for years and cause severe disability. This study was conducted to determine the prevalence of NMS in patients with PD. Methods: This cross-sectional study was performed in Isfahan, Iran, on patients with PD. The prevalence of NMS was evaluated by the NMS questionnaire, the NMS scale, and Parkinson's disease questionnaire-39 (PDQ-39). The Mini-Mental Status Examination (MMSE) was used for assessing cognition...
July 6, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29114365/stroke-subtypes-risk-factors-and-mortality-rate-in-northwest-of-iran
#19
Mehdi Farhoudi, Kaveh Mehrvar, Homayoun Sadeghi-Bazargani, Mazyar Hashemilar, Manouchehr Seyedi-Vafaee, Elyar Sadeghi-Hokmabad, Reza Rikhtegar, Babak Saber-Maroof, Mohammad Abutalebi, Mahsa Rezaei, Sahar Vaferi, Alireza Aghili, Omid Ebrahimi
Background: Stroke is the second most common cause of death and first cause of disability in adults in the world. About 80% of all stroke deaths occur in developing countries. So far, the data on stroke epidemiology have been limited in Iran. Therefore, this study was focused on stroke demographic data, risk factors, types and mortality. Methods: A retrospective study was done in two university tertiary referral hospitals in Tabriz, northwest of Iran, from March 2008 to April 2013. Patients diagnosed with stroke were enrolled in the study...
July 6, 2017: Iranian Journal of Neurology
https://www.readbyqxmd.com/read/29114364/outcome-of-subthalamic-nucleus-deep-brain-stimulation-on-long-term-motor-function-of-patients-with-advanced-parkinson-disease
#20
Gholam Ali Shahidi, Mohammad Rohani, Mansour Parvaresh, Bahram Haghi-Ashtiani, Maryam Saeedi, Romina Rashedi, Zeynab Noori-Motlagh
Background: The objective of our study was to assess Unified Parkinson Disease Rating Scale (UPDRS) score in Parkinson disease (PD) patients who underwent subthalamic nucleus (STN) deep brain stimulation (DBS) 6 years after their surgery and to compare their UPDRS score 6 years after DBS with their score before surgery and 6 months after their operation. Methods: In this cross sectional study which was carried out at Neurology Department of Rasool-e Akram Hospital, Tehran, Iran, affiliated to Iran University of Medical Sciences between 2008 and 2014, 37 patients with advanced PD were enrolled using non-randomized sampling method...
July 6, 2017: Iranian Journal of Neurology
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