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Interventional Medicine & Applied Science

Renato De Vecchis, Arturo Cesaro, Carmelina Ariano
[This retracts the article DOI: 10.1556/1646.9.2017.26.].
December 2017: Interventional Medicine & Applied Science
Vikash Kumar, Hema Chaudhary, Anjoo Kamboj
Our research objective was to develop, characterize, and optimize stable form of nano-colloidal carrier with Eudragit-coated solid lipid nanobioparticles (SLNbp) for oral delivery of isradipine (ISR). To achieve, a three factors, i.e., lipid-to-surfactant ratio (A, % w/w), Eudragit L100 (B, % w/w), and sonication time (C, minutes) at three levels (-1 and +1 levels of quality central level) was applied to develop SLNbp using response surface methodology at constant ratio of ISR and rutin. The second-order polynomial quadratic equations of responses [R1, R2, and R3; entrapment efficiency (EE), particle size, and drug release] were constructed and also plotted response surface (two- and three-dimensional) plots...
December 2017: Interventional Medicine & Applied Science
Andrii Demkovych, Yurii Bondarenko, Petro Anatoliyovych Hasiuk
The article reveals patterns of changes in the parameters of oxidative modification of proteins for different periods of the inflammatory process in periodontal tissues during periodontitis. Biochemical researches of phenylhydrazones, aldehyde-, and ketone derivatives of neutral and basic proteins were determined in the blood of white rats on the 7th, 14th, and 30th days of the experimental periodontitis development, as well as in intact animals. The method for determination of the oxidative modification of proteins was based on the interaction of oxidized amino acid residues with 2,4-dinitrophenylhydrazine to form 2,4-dinitrophenylhydrazones...
December 2017: Interventional Medicine & Applied Science
Veysel Ersan, Cuneyt Kayaalp, Aydin Aktas, Ersin Gundogan, Uygar Teomete, Fatih Sumer, Servet Karagul
The application of laparoscopic surgery via the vagina has been introduced at the beginning of this millennium. Here, we report a case of transvaginal extraction of a laparoscopic hepatectomy specimen. An exophytic liver mass originated from segment VI in a 24-year-old female was excised with laparoscopic technique using four trocars (0.5-1.2 cm sizes). The specimen (11 × 8.5 cm) was removed transvaginally instead of an abdominal incision. To the best of our knowledge, only six similar cases have been previously reported, with a patient age range of 32-74 years...
December 2017: Interventional Medicine & Applied Science
Erden Erol Unluer, Togay Evrin, Burak Katipoglu, Serdar Bayata
Fluid therapy is one of the main issues for hemodynamic resuscitation. Tissue Doppler imaging (TDI) of the right ventricle (RV) with bedside ultrasound (BUS) technique is a new dynamic method to identify fluid responsiveness in patients with hypotension. Here, we present the case of a hypotensive patient monitored with TDI measurements of RV. A 75-year-old male patient was admitted to the emergency department (ED) with the complaint of diarrhea. He was in severe hypovolemia, with hypotension, tachycardia, and tachypnea...
December 2017: Interventional Medicine & Applied Science
Oğuzhan Çelik, Lütfü Bekar, Mucahit Yetim, Tolga Doğan, Çağlar Alp, Macit Kalçık, Yusuf Karavelioğlu
Coronary pseudoaneurysms (CPAs) are rare complications developed after percutaneous coronary interventions. They may cause stent thrombosis, distal embolization, and coronary rupture leading to cardiac tamponade. Therefore, high-risk CPA should be promptly treated after diagnosis. They can be managed with percutaneous or surgical intervention. Herein, we aimed to present a patient who developed CPA 3 weeks after percutaneous coronary intervention and successfully treated with percutaneous intervention using a covered stent...
December 2017: Interventional Medicine & Applied Science
Mehri Seifoleslami
Thrombocytopenia occurs to approximately 8%-10% of pregnant women and this condition is a notable source of morbidity and mortality during pregnancy. In the recent years, our comprehension of thrombocytopenia has progressed on pregnancy. Nevertheless, there has not been adequate information about thrombocytopenia outcomes in obstetric patients. With regard to this topic, we reviewed published reports as an update from the managements on these cases. Nevertheless, recommendations for management of delivery in obstetric women with thrombocytopenia are based on several hypotheses requiring critical analysis...
December 2017: Interventional Medicine & Applied Science
Rozana Nazaryan, Liudmyla Kryvenko
Background and aims: Prevalence of atopic diseases is progressively increasing in children with unclear clinical picture in oral cavity. This study aimed to find correlation between the total antioxidant and periodontal status in the saliva of periodontally compromised with atopy. Materials and methods: The groups consisted of patients of atopic diseases and gingivitis (ADG), of atopic diseases without gingivitis (AD), and healthy controls (HC). The level of gingival inflammation was evaluated using the sulcus bleeding index (SBI) reported by Mühlemann and Son...
December 2017: Interventional Medicine & Applied Science
Kausar Jaha Yadwad, H R Veena, Sudhir R Patil, B M Shivaprasad
Introduction: Chronic periodontitis (CP) is an infectious disease resulting in inflammation of the supporting tissues of the teeth with progressive attachment loss and bone loss. This study aimed to evaluate the effect of 980-nm diode laser, as an adjunct to scaling and root planing (SRP) in the management of CP. Methodology: A total of 40 systemically healthy subjects diagnosed with CP were randomly assigned into two groups G1 (SRP and sham application of laser) and G2 (SRP and laser irradiation) with equal numbers in each...
December 2017: Interventional Medicine & Applied Science
Mehdi Mogharnasi, Kazem Cheragh-Birjandi, Sadegh Cheragh-Birjandi, Hossein TaheriChadorneshin
Background: Studies show that different types of training have a significant role in reducing both new and traditional risk factors of cardiovascular diseases, and the new risk factors are more sensitive and accurate in predicting such diseases. Objective: The aim of this study was to determine the effects of resistance and endurance exercises on risk factors of vascular inflammation and atherogenesis in non-athlete men. Methods: Thirty-six non-athlete male students (mean age: 20...
December 2017: Interventional Medicine & Applied Science
Hamid Arazi, Siavash Rahmati, Hosein Ghafoori
Background: Anabolic-androgenic steroids (AAS) are synthetic drugs derived from testosterone, the uncontrolled usage of which may lead to serious side effects. Previous studies have shown that resistance training (RT) is the main exercise modality practiced by AAS abusers. Thus, this work was carried out to evaluate the hepatotoxic effects of sustanon (Su) as an example of AAS in trained male rats. Methods: Rats were divided into sedentary/non-Su, sedentary/Su, RT/non-Su, and RT/Su...
September 2017: Interventional Medicine & Applied Science
Ludmila Davydova, Gennadii Tkach, Alexey Tymoshenko, Alexey Moskalenko, Vitalii Sikora, Ludmila Kyptenko, Mykola Lyndin, Dmytro Muravskyi, Olena Maksymova, Olga Suchonos
Purpose: The purpose of this paper is to describe the research results of the morphological structure of white laboratory rats' tongue at the macro-, micro-, and ultrastructural levels by scanning, light, and transmission electron microscopy. Results: Our results show that the tongue of these rats has a number of unique morphological features that are different from the tongue of other rodents consequently to allow identifying their species-specific features. Conclusions: Our findings have shown the features of the tongue structure of white laboratory rats at micro-, macro-, and ultrascopic levels...
September 2017: Interventional Medicine & Applied Science
Mansour Al-Askar
Introduction: Although several studies have investigated the relationship between ABO blood group and medical diseases, few reports have explored the association with oral diseases, including periodontal disease (PD). Aim: The aim of this literature review was to assess the association between the ABO blood grouping and PD. Methods: We searched PubMed and Google Scholar databases using the following terms in different combinations: "ABO blood group," "periodontitis," "aggressive periodontitis (AP)," "risk factor," and "Rhesus factor...
September 2017: Interventional Medicine & Applied Science
Petro Hasiuk, Anna Vorobets, Nataliya Hasiuk, Svitlana Rosolovska, Irina Bodnarchuk, Volodymyr Radchuk
Modern reconstructive methods of dentistry (stopping, restoration, and prosthetics with different types of orthopedic constructions) require detailed examination of the anatomical structure of the teeth crowns, especially examination of the knowledge about the relief of masticatory surface. That is why, we conducted a detailed examination of the features of odontoglyphics of molars, according to the sex and determination the odontometrical teeth indices of the citizens of Ternopil region. To achieve the goals, we use the following research methods, such as odontological, odontometrical, and statistical...
September 2017: Interventional Medicine & Applied Science
Oğuzhan Çelik, Erkan Demirci, Mustafa Aydın, Turgut Karabag, Macit Kalçık
Background: Ghrelin has recently been reported to have beneficial effects on cardiac contractile functions and coronary blood flow. The main purpose of this study was to investigate the role of ghrelin in the pathogenesis of coronary slow flow (CSF) together with endothelial functions. Methods: Twenty-five patients having normal coronary arteries with CSF and 25 controls with normal coronary flow were included into the study. The quantitative measurement of coronary blood flow was performed for each coronary artery using the thrombolysis in myocardial infarction (TIMI) frame count (TFC) method...
September 2017: Interventional Medicine & Applied Science
Macit Kalçık, Mahmut Yesin, Emrah Bayam, Mustafa Ozan Gürsoy, Ahmet Güner, Sabahattin Gündüz, Mehmet Özkan
Prosthetic valve thrombosis (PVT) is a life-threatening complication in pregnant women with mechanical prosthetic heart valves. Thrombolytic therapy (TT) has evolved as an effective treatment alternative to surgery, which is associated with very high maternal and fetal mortality and morbidity in these patients. Acute ischemic stroke may rarely occur during TT for PVT. Here, we present a pregnant patient who was complicated with cerebral thromboembolism during TT for PVT and successfully managed with continuation of TT...
September 2017: Interventional Medicine & Applied Science
Volodymyr M Kozko, Andriy V Bondarenko, Anatoliy V Gavrylov, Olga S Shevchenko, Vitalii V Gargin
Background and aims: One of the most severe manifestation displays of tuberculosis (TB) generalization is meningitis/meningoencephalitis. The purpose of this work was to improve the diagnostic efficiency of TB central nervous system (CNS) affection in human immunodeficiency virus (HIV)-infected persons. Materials and methods: Meninges and cerebral tissues, taken from died patients, who were HIV-infected and dead from TB of CNS affection, were investigated histologically...
September 2017: Interventional Medicine & Applied Science
Ahmed Al Kuwaiti
Background and aims: Few studies have reported the correlation between hand hygiene (HH) practices and infection rates in Saudi Arabia. This work was aimed to study the effect of a multicomponent HH intervention strategy in improving HH compliance and reducing infection rates at King Fahd Hospital of the University, Al-Khobar, Saudi Arabia between January 2014 and December 2016. Methods: A yearlong multicomponent HH intervention, which included various strategies recommended by the World Health Organization, was introduced...
September 2017: Interventional Medicine & Applied Science
Renato De Vecchis, Arturo Cesaro, Carmelina Ariano
Background: Phosphodiesterase-5 inhibitors (PDE5i) have been shown to be beneficial for patients with pulmonary arterial hypertension. However, several studies would have documented a useful effect of PDE5i even for pulmonary hypertension secondary to left-sided chronic heart failure (CHF). Methods: We performed a meta-analysis including randomized controlled trials (RCTs) which had compared PDE5i (mostly sildenafil) and placebo in CHF patients. Results: Fourteen studies enrolling a total of 928 patients were incorporated in the meta-analysis...
September 2017: Interventional Medicine & Applied Science
Nurzen Sezgin, Abdullah Tekin, Fatma Belgin Atac, Hasibe Verdi, Alpay Turan Sezgin
Background and aims: The aim of this study was to explore potential associations of the intron 4 variable number of tandem repeats (VNTR) and E298A polymorphisms of the endothelial nitric oxide synthase (eNOS) gene with slow coronary flow (SCF). The association between plasma nitrate and nitrite (NO x ) concentrations and eNOS gene polymorphisms was also assessed. Materials and methods: The intron 4 VNTR and E298A polymorphisms of the eNOS gene were evaluated in the isolated DNA blood samples obtained from the SCF patient group ( n  = 30) and healthy group consisted of age- and sex-matched controls ( n  = 61)...
September 2017: Interventional Medicine & Applied Science
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