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Infection & Chemotherapy

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https://www.readbyqxmd.com/read/29299900/guidelines-for-the-antibiotic-use-in-adults-with-acute-upper-respiratory-tract-infections
#1
REVIEW
Young Kyung Yoon, Chan Soon Park, Jae Wook Kim, Kyurin Hwang, Sei Young Lee, Tae Hoon Kim, Do Yang Park, Hyun Jun Kim, Dong Young Kim, Hyun Jong Lee, Hyun Young Shin, Yong Kyu You, Dong Ah Park, Shin Woo Kim
These guidelines were developed as part of the 2016 Policy Research Servicing Project by the Korea Centers for Disease Control and Prevention. A multidisciplinary approach was taken to formulate this guideline to provide practical information about the diagnosis and treatment of adults with acute upper respiratory tract infection, with the ultimate aim to promote the appropriate use of antibiotics. The formulation of this guideline was based on a systematic literature review and analysis of the latest research findings to facilitate evidence-based practice, and focused on key questions to help clinicians obtain solutions to clinical questions that may arise during the care of a patient...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29299899/clinical-guidelines-for-the-antibiotic-treatment-for-community-acquired-skin-and-soft-tissue-infection
#2
Yee Gyung Kwak, Seong Ho Choi, Tark Kim, Seong Yeon Park, Soo Hong Seo, Min Bom Kim, Sang Ho Choi
Skin and soft tissue infection (SSTI) is common and important infectious disease. This work represents an update to 2012 Korean guideline for SSTI. The present guideline was developed by the adaptation method. This clinical guideline provides recommendations for the diagnosis and management of SSTI, including impetigo/ecthyma, purulent skin and soft tissue infection, erysipelas and cellulitis, necrotizing fasciitis, pyomyositis, clostridial myonecrosis, and human/animal bite. This guideline targets community-acquired skin and soft tissue infection occurring among adult patients aged 16 years and older...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29299898/a-case-of-community-acquired-pneumonia-caused-by-multidrug-resistant-acinetobacter-baumannii-in-korea
#3
Young Woong Son, In Young Jung, Mi Young Ahn, Yong Duk Jeon, Hea Won Ann, Jin Young Ahn, Nam Su Ku, Sang Hoon Han, Jun Young Choi, Young Goo Song, June Myung Kim
Acinetobacter baumannii is an aerobic Gram-negative coccobacillus that causes nosocomial pneumonia in patients on mechanical ventilation or previously treated with broad-spectrum antibiotics. Nevertheless, community-acquired pneumonia (CAP) caused by A. baumannii, especially multi-drug resistant (MDR) strains, is rare. We experienced the first case of CAP caused by MDR A. baumannii in Korea in a 78-year-old man. This case shows that MDR A. baumannii can cause CAP in Korea.
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29299897/successful-treatment-of-protothecal-tenosynovitis-in-an-immunocompetent-patient-using-amphotericin-b-deoxycholate
#4
Ji Eun Kim, Tae Hoon Oh, Kyung Hwa Lee, Jong Hee Shin, Sook In Jung
Protothecosis is an uncommon human infection caused by achlorophyllic algae of the genus Prototheca, especially P. wickerhamii. The skin is the most frequently involved organ and cases of protothecal tenosynovitis are very rare. A 71-year-old woman without prior medical history except hypertension presented with painful swelling of her right hand that did not improve despite receiving antibiotic treatment. She underwent tenosynovectomy and drainage. Histopathologic examination revealed necrotizing granulomatous inflammation and numerous spherical or morula-like organisms with a spoked wheel appearance...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29299896/infective-endocarditis-presenting-as-endogenous-endophthalmitis-secondary-to-streptococcus-agalactiae-in-a-healthy-adult-case-reports-and-literature-review
#5
Yu Ra Sim, Ye Jin Lee, Seung Woon Park, Sang Hyun Kim, Ju Hee Choi, Jung Yoon Choi, Min Ja Kim, Jang Wook Sohn, Jaemoon Ahn, Young Kyung Yoon
Endogenous endophthalmitis secondary to group B Streptococcus (GBS) is extremely rare, particularly in healthy adults. However, the visual prognosis is poor. We report the first South Korean case of GBS infective endocarditis presenting as endogenous endophthalmitis and skin and soft tissue infection. Cultures of blood, vitreous humor, and pus from skin aspirates yielded a penicillin-susceptible serotype V strain of Streptococcus agalactiae. After 6 weeks, the patient completely recovered from GBS infective endocarditis...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29299895/community-acquired-escherichia-coli-enteritis-in-korean-children-the-clinical-application-of-a-stool-polymerase-chain-reaction-assay
#6
Youie Kim, Hyo Jin Kim, Sooyeon Lim, Kil Seong Bae, Seung Beom Han, Dae Chul Jeong, Jin Han Kang, Gook Jae Shin, Gun Dong Lee, Yeon Joon Park
BACKGROUND: Although Escherichia coli is a common cause of bacterial enteritis in Korea, reports on community-acquired E. coli enteritis in Korean children are scarce. This study aimed to determine the clinical characteristics and pathotype distribution of community-acquired E. coli enteritis diagnosed by a multiplex polymerase chain reaction (PCR) assay in Korean children. MATERIALS AND METHODS: The medical records of children aged 18 years or less who were diagnosed with acute gastroenteritis by the attending physician between 2013 and 2016 were retrospectively reviewed...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29299894/human-immunodeficiency-virus-hiv-and-hepatitis-virus-coinfection-among-hiv-infected-korean-patients-the-korea-hiv-aids-cohort-study
#7
Yong Chan Kim, Jin Young Ahn, June Myung Kim, Youn Jeong Kim, Dae Won Park, Young Kyung Yoon, Joon Young Song, Shin Woo Kim, Jin Soo Lee, Bo Youl Choi, Yun Su Choi, Ju Yeon Choi, Myung Guk Han, Chun Kang, Jun Yong Choi
BACKGROUND: Despite declines in mortality and morbidity rates of patients with human immunodeficiency virus (HIV) infection as the result of highly active antiretroviral therapy, liver diseases due to chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are a leading cause of death among HIV-infected patients. However, HIV and HBV or HCV coinfection is still poorly documented, and more information is needed to better understand the characteristics of HIV-infected patients in Korea...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29299893/response-of-vancomycin-according-to-steroid-dosage-in-pediatric-patients-with-culture-proven-bacterial-meningitis
#8
Shin Ae Lee, Jin Kyu Kim, Dae Sun Jo, Sun Jun Kim
BACKGROUND: This study aimed to evaluate the efficacy of combined vancomycin and steroid therapy for the treatment of culture-proven bacterial meningitis in pediatric patients. MATERIALS AND METHODS: We identified a total of 86 pediatric patients with culture-positive cerebrospinal fluid who were treated at our facility between 2005 and 2015. Ten of these patients (5 boys and 5 girls) received first-line treatment with vancomycin as the initial form of therapy. All cultured bacteria were sensitive to vancomycin...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29299892/cytomegalovirus-infection-after-renal-transplantation-occurrence-clinical-features-and-the-cutoff-for-antigenemia-in-a-university-hospital-in-brazil
#9
Sócrates Bezerra de Matos, Roberto Meyer, Fernanda Washington de Mendonça Lima
BACKGROUND: Cytomegalovirus (CMV) is the main infectious agent causative of morbidity and mortality in transplant recipients. This study aimed to describe the occurrence and clinical features of CMV infection, and the optimum antigenemia assay cutoff associated with symptomatic infection. MATERIALS AND METHODS: This was a cohort study that investigated 87 patients undergoing renal transplantation. The patients were monitored with the CMV antigenemia assay performed weekly for the first 3 months post-transplantation and subsequently, when CMV infection was suspected clinically...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29299891/the-korean-influenza-national-immunization-program-history-and-present-status
#10
REVIEW
Jae Won Yun, Ji Yun Noh, Joon Young Song, Chaemin Chun, Yunju Kim, Hee Jin Cheong
The Korean influenza national immunization program was first established as an interim program in 1997, administering the influenza vaccine to low-income elderly adults. In 2005, the program assumed its present form of providing free influenza vaccination to adults aged ≥65 years. After turning over the influenza vaccination for elderly adults to the private sectors in 2015, the influenza vaccination coverage rate among this population increased to >80%. In addition, after the 2009 H1N1 influenza epidemic crisis, the vaccine was domestically produced...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29027392/summary-of-guidelines-for-the-use-of-pre-exposure-prophylaxis-for-hiv-in-korea
#11
REVIEW
(no author information available yet)
There are several guidelines for the use of pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) which are used in other countries. However, the implementation of such guidelines in each country should be modified according to the country's clinical and epidemiological situation. Therefore, The Korean Society for AIDS founded a committee in 2016 to develop guidelines for the use of PrEP for HIV that are optimal for Korea's clinical and epidemiological situation. These guidelines aim to provide comprehensive information for PrEP implementation in Korea...
September 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29027391/regional-experience-of-abacavir-valuable-but-still-has-unanswered-question
#12
EDITORIAL
Ji Hwan Bang
No abstract text is available yet for this article.
September 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29027390/renal-disease-in-persons-infected-with-human-immunodeficiency-virus-in-korea
#13
EDITORIAL
Pyoeng Gyun Choe
No abstract text is available yet for this article.
September 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29027389/biofilm-formation-and-antimicrobial-resistance-in-enterococcus
#14
EDITORIAL
Yangsoon Lee
No abstract text is available yet for this article.
September 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29027388/causes-of-hiv-drug-non-adherence-in-korea-korea-hiv-aids-cohort-study-2006-2015
#15
Min Jung Kim, Sang Ah Lee, Hyun Ha Chang, Min Ja Kim, Jun Hee Woo, Sang Il Kim, Chun Kang, Mee Kyung Kee, Ju Yeon Choi, Yunsu Choi, Bo Youl Choi, June Myung Kim, Jun Yong Choi, Hyo Youl Kim, Joon Young Song, Shin Woo Kim
We aimed to determine the initial adherence of HIV cohort patients to ART (antiretroviral therapy), and reasons for non-adherence. Patients who received ART at the time of enrollment in the Korea HIV/AIDS Cohort were included in this study. Treatment adherence was determined at the baseline interview by self-reported questionnaire. Eight-hundred thirty two HIV-infected patients received ART. Of these, 253 (30.4%) patients skipped ART more than once a month. The most common reason of skipping medication was "simply forgot" (60...
September 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29027387/safety-and-efficacy-of-ziagen-abacavir-sulfate-in-hiv-infected-korean-patients
#16
Heawon Ann, Ki Hyon Kim, Hyun Young Choi, Hyun Ha Chang, Sang Hoon Han, Kye Hyung Kim, Jin Soo Lee, Yeon Sook Kim, Kyung Hwa Park, Young Keun Kim, Jang Wook Sohn, Na Ra Yun, Chang Seop Lee, Young Wha Choi, Yil Seob Lee, Shin Woo Kim
BACKGROUND: Abacavir is a widely-used nucleoside reverse transcriptase inhibitor for the treatment of human immunodeficiency virus (HIV) infection. Mandatory postmarketing surveillance was conducted in Korea to monitor the safety and evaluate the effectiveness of Ziagen® (abacavir sulfate 300 mg; ViiV Healthcare, Middlesex, UK). MATERIALS AND METHODS: An open-label, multi-center, non-interventional postmarketing surveillance study was conducted from June 2010 to June 2016 to monitor the safety and effectiveness of Ziagen across 12 hospitals in Korea...
September 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29027386/the-prevalence-and-risk-factors-of-renal-insufficiency-among-korean-hiv-infected-patients-the-korea-hiv-aids-cohort-study
#17
Eun Jin Kim, Jin Young Ahn, Youn Jeong Kim, Seong Heon Wie, Dae Won Park, Joon Young Song, Hee Jung Choi, Hyun Ha Chang, Bo Youl Choi, Yunsu Choi, Ju Yeon Choi, Myung Guk Han, Chun Kang, June Myung Kim, Jun Yong Choi
BACKGROUND: Renal disease is one of the leading causes of morbidity and mortality among people infected with human immunodeficiency virus (HIV). However, there are very few published studies about renal insufficiency in HIV-infected persons in Asia, especially in South Korea. MATERIALS AND METHODS: A cross-sectional study was performed to investigate the prevalence and risk factors of renal insufficiency, defined as <60 mL/min/1.73 m², in subjects in the Korea HIV/AIDS Cohort Study enrolled from 19 institutions between December 2006 and July 2013...
September 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29027385/antimicrobial-susceptibilities-of-enterobacteriaceae-in-community-acquired-urinary-tract-infections-during-a-5-year-period-a-single-hospital-study-in-korea
#18
Jin Ju Park, Yu Bin Seo, Jacob Lee
BACKGROUND: Through investigating antimicrobial susceptibility patterns of Enterobacteriaceae in community-acquired urinary tract infection (CA-UTI), we provide basic evidence for the use of empirical antibiotics in CA-UTI. MATERIALS AND METHODS: We retrospectively reviewed the medical records of patients over the age of 19 years who visited a hospital in Seoul between January 2012 and December 2016 for a CA-UTI. Urine cultures were used to identify causative organisms...
September 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29027384/survey-for-correlation-between-biofilm-formation-and-virulence-determinants-in-a-collection-of-pathogenic-and-fecal-enterococcus-faecalis-isolates
#19
Fereshteh Saffari, Mohammad Sadegh Dalfardi, Shahla Mansouri, Roya Ahmadrajabi
BACKGROUND: Enterococcus faecalis is an opportunistic pathogen that causes most of the enterococcal infections. Among the different factors implicated in the pathogenesis of these organisms, biofilm formation and antibiotic resistance are the most important. The ability for biofilm formation has been attributed to the presence of some virulence genes. However, no definite correlation has been found. This study aimed to detect biofilm formation and antibiotic resistance patterns in E. faecalis isolates collected from clinical and fecal samples, and to investigate possible correlation between some virulence genes (esp, cyl, gelE) and biofilm formation...
September 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29027383/immunological-prediction-of-cytomegalovirus-cmv-replication-risk-in-solid-organ-transplantation-recipients-approaches-for-regulating-the-targeted-anti-cmv-prevention-strategies
#20
REVIEW
Sang Hoon Han
The current cytomegalovirus (CMV) prevention strategies in solid organ transplantation (SOT) recipients have contributed towards overcoming the detrimental effects caused by CMV lytic infection, and improving the long-term success rate of graft survival. Although the quantification of CMV in peripheral blood is the standard method, and an excellent end-point for diagnosing CMV replication and modulating the anti-CMV prevention strategies in SOT recipients, a novel biomarker mimicking the CMV control mechanism is required...
September 2017: Infection & Chemotherapy
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