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Postȩpy Dermatologii i Alergologii

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https://www.readbyqxmd.com/read/29610568/longer-ta-repeat-but-not-v89l-polymorphisms-in-the-srd5a2-gene-may-confer-acne-risk-in-the-chinese-population
#1
Xue Hu, Wei Ding, Xinye Jin, Jia Wang, Dajin Zou, Yue Chen
Introduction: Several studies have reported that the V89L and TA repeat polymorphisms [(TA)n] of the SRD5A2 gene were associated with SRD5A2 activity. The activity of dihydrotestosterone, which is converted from testosterone by SRD5A2, is responsible for sebum secretion and the formation of acne. We hypothesized that abnormalities in SRD5A2 action could contribute to the formation of acne. Aim: To study whether the structural change of the SRD5A2 gene may affect the risk of acne in patients with normal serum testosterone levels...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599684/occupational-exposure-as-a-presumable-cause-of-subcutaneous-sarcoidosis-in-a-tannery-worker-case-report-and-review-of-the-literature
#2
Małgorzata M Michalska-Jakubus, Katarzyna Zdeb, Beata Rymgayłło-Jankowska, Agnieszka Korolczuk, Tomasz Żarnowski, Dorota Krasowska
No abstract text is available yet for this article.
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599683/pityriasis-rosea-in-a-patient-with-retrovirus-infection-a-reply
#3
Giulia Ciccarese, Aurora Parodi, Francesca Drago, Astrid Herzum, Francesco Drago
No abstract text is available yet for this article.
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599682/paraneoplastic-pemphigus-with-anti-desmocollin-3-autoantibodies-and-chronic-lymphocytic-leukemia
#4
Alicja Adaszewska, Norito Ishii, Jadwiga Dwilewicz-Trojaczek, Katarzyna Woźniak, Takashi Hashimoto, Cezary Kowalewski
No abstract text is available yet for this article.
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599681/a-case-of-granuloma-faciale-successfully-treated-with-oral-prednisone-tranilast-and-thalidomide
#5
Chunyu Yuan, Wenbo Bu, Xu Chen, Heng Gu
No abstract text is available yet for this article.
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599680/the-first-case-of-drug-induced-pseudoscleroderma-and-eczema-craquel%C3%A3-related-to-nab-paclitaxel-pancreatic-adenocarcinoma-treatment
#6
Małgorzata Sokołowska-Wojdyło, Joanna Kłudkowska, Berenika Olszewska, Joanna Seredyńska, Wojciech Biernat, Izabela Błażewicz, Alicja Rustowska-Rogowska, Roman J Nowicki
No abstract text is available yet for this article.
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599679/seasonal-variation-of-asthma-control-lung-function-tests-and-allergic-inflammation-in-relation-to-vitamin-d-levels-a-prospective-annual-study
#7
Sehra Birgül Batmaz, Tuğba Arıkoğlu, Lülüfer Tamer, Gülçin Eskandari, Semanur Kuyucu
Introduction: There are scarce data about the role of vitamin D (vitD) in asthma control related to seasons and other confounders. Aim: To investigate the seasonal relationship between vitD levels and asthma control, lung function tests (LFTs) and cytokines during a 1-year period, among 7-17-year-old asthmatic children. Material and methods: Thirty patients with asthma with house dust mite monosensitization were evaluated 3 monthly about the previous month's health and vitD related lifestyle factors and asthma control test (ACT), spirometry and bronchial provocation test for a year...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599678/the-usefulness-of-the-basophil-activation-test-in-monitoring-specific-immunotherapy-with-house-dust-mite-allergens
#8
Ewa M Czarnobilska, Małgorzata Bulanda, Radosław Śpiewak
Introduction: In clinical practice, reliable tools for monitoring specific immunotherapy (SIT) are of utmost importance. Aim: To assess the usefulness of the basophil activation test (BAT) in monitoring SIT in paediatric patients with allergy to house dust mites (HDM). Material and methods: Thirty-one children qualified for SIT with HDM, of whom 21 completed the SIT during the observation period. The BAT was carried out prior to commencing the SIT (time point BAT1) and upon finishing the initial pack of allergy vaccine (cumulative dose of allergen 12487...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599677/venom-immunotherapy-and-pregnancy
#9
Krzysztof Pałgan, Magdalena Żbikowska-Götz, Elżbieta Chrzaniecka, Zbigniew Bartuzi
Introductions: The efficiency of venom immunotherapy (VIT) has been well documented by many studies. However, the most important for VIT is safety, particularly for a pregnant woman and a fetus. Aim: To establish the influence of continuation of VIT on pregnant women and offspring. Material and methods: The 6 women became pregnant during a specific immunotherapy. We retrospectively analyzed the influence of the immunotherapy on any complications for the pregnant women and their infants...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599676/cross-sensitization-to-artemisia-and-ambrosia-pollen-allergens-in-an-area-located-outside-of-the-current-distribution-range-of-ambrosia
#10
Łukasz Grewling, Dorota Jenerowicz, Paweł Bogawski, Matt Smith, Małgorzata Nowak, Agata Frątczak, Magdalena Czarnecka-Operacz
Introduction: The role of long-distance transported (LDT) Ambrosia pollen in inducing new sensitization and affecting sensitization rates in Artemisia -sensitized patients is unclear. Aim: The aim of this study was to estimate the degree of cross-sensitization to Ambrosia/Artemisi a allergens in citizens of Poznan (Western Poland). This area is covered by extensive Artemisia populations but does not currently have local Ambrosia populations. Material and methods: Sera of 119 patients were tested by fluoroenzyme immunoassay (CAP-FEIA system) against pollen allergen extracts of Artemisia vulgaris and Ambrosia artemisiifolia , an allergenic component of A...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599675/activity-of-antimicrobial-peptides-and-conventional-antibiotics-against-superantigen-positive-staphylococcus-aureus-isolated-from-patients-with-atopic-dermatitis
#11
Izabela Błażewicz, Maciej Jaśkiewicz, Lidia Piechowicz, Damian Neubauer, Roman J Nowicki, Wojciech Kamysz, Wioletta Barańska-Rybak
Introduction: Staphylococcus aureus causes a diverse array of diseases, ranging from relatively harmless localized skin infections to life-threatening systemic conditions. It secretes toxins directly associated with particular disease symptoms. Aim: To determine the prevalence of methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) colonization among patients with atopic dermatitis and to assess the antimicrobial susceptibility to conventional antibiotics and selected antimicrobial peptides among toxin-producing strains and nonproducing strains...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599674/epidemiology-of-urticaria-in-poland-nationally-representative-survey-results
#12
Filip Raciborski, Anna Kłak, Magdalena Czarnecka-Operacz, Dorota Jenerowicz, Adam Sybilski, Piotr Kuna, Bolesław Samoliński, Eup Wg
Introduction: The prevalence of urticaria is 15-20%. Women are twice as likely to be affected. Aim: To present the epidemiology of urticaria and angioedema in Poland. Material and methods: A questionnaire-based survey was conducted on a representative group of 4,897 individuals, aged 15-74 years. Results: A total of 11.2% of respondents reported at least one episode of urticaria symptoms in their life, and the frequency was higher in females (OR = 1...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599673/associations-between-site-of-skin-lesions-and-depression-social-anxiety-body-related-emotions-and-feelings-of-stigmatization-in-psoriasis-patients
#13
Patryk Łakuta, Kamil Marcinkiewicz, Beata Bergler-Czop, Ligia Brzezińska-Wcisło, Anna Słomian
Introduction: Research has demonstrated a link between psoriasis and a multitude of psychological impairments; however, relatively few studies have examined the importance of site of skin lesions for negative psychological outcomes in psoriasis patients. Aim: To investigate relationships between anatomical location of psoriatic lesions and experiences of stigmatization, negative emotional attitude towards the body, depression and social anxiety. Material and methods: Adult psoriasis patients ( N = 193) completed the Stigmatization Scale, the Body Emotions Scale, the Beck Depression Inventory and the Social Anxiety Questionnaire...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599672/the-effect-of-subcutaneous-methotrexate-on-markers-of-metabolic-syndrome-in-psoriatic-patients-preliminary-report
#14
Agnieszka Owczarczyk-Saczonek, Marek Drozdowski, Agata Maciejewska-Radomska, Dariusz Choszcz, Waldemar Placek
Introduction: Methotrexate (MTX) has anti-proliferative and anti-inflammatory effects in psoriasis. Moreover, low doses can reduce the risk of developing cardiovascular diseases. It turns out that psoriasis and atherosclerosis have a similar pathogenetic mechanism: the same pro-inflammatory cytokines, Th1 and Th17, are involved in both diseases. Aim: To evaluate the effects of metabolic markers, protective cytokines (interleukin 10 (IL-10), transforming growth factor β (TGF-β)) and a marker of endothelial damage (endocan) in patients with plaque psoriasis...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599671/trends-in-basal-cell-carcinoma-incidence-rates-a-16-year-retrospective-study-of-a-population-in-central-poland
#15
Magdalena Ciążyńska, Joanna Narbutt, Anna Woźniacka, Aleksandra Lesiak
Introduction: Basal cell carcinoma (BCC) is the most commonly occurring cancer worldwide, and the overall incidence is still rising. Unfortunately, the cancer registry in Poland does not record BCC individually. Thus, the incidence of BCC in a defined population is unknown. Aim: Analysis of incidence rates of primary BCC in central Poland during 16 years considering sex, site distribution and age to determine trends. Material and methods: We retrospectively included all cases of BCC which were diagnosed and treated in the Department of Dermatology and Venereology, Medical University of Lodz, during the 16-year period from 1999 to 2015...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599670/dermoscopic-assessment-of-skin-toxicities-in-patients-with-melanoma-during-treatment-with-vemurafenib
#16
Marcin Rajczykowski, Grazyna Kaminska-Winciorek, Elzbieta Nowara, Marzenna Samborska-Plewicka, Sebastian Giebel
Introduction: The use of vemurafenib in melanoma has improved the survival of patients; however, it is associated with skin toxicities. Aim: To assess skin toxicities by dermoscopy in patients treated with vemurafenib. Material and methods: Eight patients with BRAF V600 mutation positive metastatic melanoma were examined dermoscopically during vemurafenib treatment. All skin lesions occurring during therapy were assessed clinically and dermoscopically using a hand-held dermoscope with polarised and non-polarised light...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599669/x-linked-tlr7-gene-polymorphisms-are-associated-with-diverse-immunological-conditions-but-not-with-discoid-lupus-erythematosus-in-polish-patients
#17
Katarzyna Skonieczna, Anna Woźniacka, Rafał Czajkowski, Jan Styczyński, Anna Krenska, Ewa Robak, Mariusz Gawrych, Sebastian Kaszewski, Mariusz Wysocki, Tomasz Grzybowski
Introduction: Toll-like receptor 7 (TLR7) is an important molecule involved in the development of autoimmunity and the response to different pathogens. Several polymorphisms within the TLR7 gene were previously found to be associated with systemic lupus erythematosus (SLE). However, none of those studies investigated the TLR7 promoter flanking variants rs1634318 and rs1616583. TLR7 gene diversity has not been analyzed with respect to discoid lupus erythematosus (DLE) development, while its role in the human immunological response to fungal infection is not fully known...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599668/selected-presentations-of-lip-enlargement-clinical-manifestation-and-differentiation
#18
REVIEW
Katarzyna J Błochowiak, Bartłomiej Kamiński, Henryk Witmanowski, Jerzy Sokalski
Lip enlargement may be an important symptom of either systemic or local diseases. On the basis of selected age-matched clinical cases we present the possible causes of lip swelling. We describe the most representative symptoms and recommend treatment of these pathologies. We differentiate lip swelling in Miescher syndrome, monosymptomatic form of Melkersson-Rosenthal syndrome, lip swelling in erythema multiforme and Stevens-Johnson syndrome and lip hemangioma and mucous extravasation cyst. We compare different causes of lip edema and indicate the most helpful diagnostic and treatment methods...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599667/langerhans-cell-histiocytosis-in-children-a-disease-with-many-faces-recent-advances-in-pathogenesis-diagnostic-examinations-and-treatment
#19
REVIEW
Michalina Jezierska, Joanna Stefanowicz, Grzegorz Romanowicz, Wojciech Kosiak, Magdalena Lange
Langerhans cell histiocytosis is a rare clonal disease characterized by the proliferation of CD1a-positive immature dendritic cells. The purpose of this article was to present an updated review of recent advances in the pathogenesis, clinical features, imaging and treatment of this disease. The discovery of oncogenic BRAF mutations and the presence of proinflammatory cytokines and chemokines confirmed the unusual characteristics of this disease. Currently, children with organ involvement who do not have a good response to chemotherapy and have neurodegeneration or diabetes insipidus are the most problematic patients...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29599666/structure-and-function-of-the-epidermal-barrier-in-patients-with-atopic-dermatitis-treatment-options-part-one
#20
REVIEW
Jagoda Pelc, Magdalena Czarnecka-Operacz, Zygmunt Adamski
Atopic dermatitis is a chronic, recurrent inflammatory skin disease, which is frequently familial. The main cause of the disease seems to be a defect of the epidermal barrier resulting from a genetic predisposition concerning the epidermis, functioning of the immune system as well as environmental factors (which are not related to the immune system). Genes responsible for encoding protein S100, filaggrin, proteases and their inhibitors are the main genes related to the problem of epidermal barrier dysfunction...
February 2018: Postȩpy Dermatologii i Alergologii
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