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Postȩpy Dermatologii i Alergologii

Diego Orsini, Andrea D'Arino, Flavia Pigliacelli, Chiara Assorgi, Alessandra Latini, Antonio Cristaudo
No abstract text is available yet for this article.
October 2018: Postȩpy Dermatologii i Alergologii
Alina Jankowska-Konsur, Karolina Kopeć-Pytlarz, Zdzisław Woźniak, Anita Hryncewicz-Gwóźdź, Joanna Maj
No abstract text is available yet for this article.
October 2018: Postȩpy Dermatologii i Alergologii
Katarzyna Osipowicz, Cezary Kowalewski, Katarzyna Woźniak
No abstract text is available yet for this article.
October 2018: Postȩpy Dermatologii i Alergologii
Justyna Emeryk-Maksymiuk, Anna Grzywa-Celińska, Sławomir Woźniak, Piotr Szkodziak, Michał Szczyrek
No abstract text is available yet for this article.
October 2018: Postȩpy Dermatologii i Alergologii
Marcello Albanesi, Attilio Di Girolamo, Vincenzo Aresta, Maria Pia Rossi, Lucia Giliberti, Tommasina Perrone, Danilo Di Bona, Maria Filomena Caiaffa, Giorgina Specchia, Luigi Macchia
No abstract text is available yet for this article.
October 2018: Postȩpy Dermatologii i Alergologii
Andrzej Namysłowski, Bolesław K Samoliński, Agnieszka Lipiec, Wojciech Zieliński, Adam J Sybilski, Artur Walkiewicz, Piotr Samel-Kowalik, Krzysztof Samoliński, Filip Raciborski
Introduction: Specific immunoglobulins E (sIgE) are important parameters to estimate severity of allergic diseases. Aim: To determine the influence of allergy risk factors on the concentration of specific IgE antibodies in serum. Material and methods: The concentration of sIgE antibodies against allergens Dermatophagoides pteronyssinus , cat dander, timothy grass, Alternaria alternata were determined in serum of 4077 respondents randomly selected from 9 regions (ECAP study)...
October 2018: Postȩpy Dermatologii i Alergologii
Songül Çildağ, Taşkın Şentürk
Introduction: Suppression of free immunoglobulin E (IgE) levels and an increase in total IgE levels are observed during omalizumab treatment. However, whether omalizumab has any effect on other immunoglobulins is unknown. Aim: To investigate the effect of omalizumab treatment on serum IgE and other immunoglobulins, and demonstrate any association with response to treatment in patients with chronic spontaneous urticaria (CSU). Material and methods: The study included 41 patients diagnosed with CSU...
October 2018: Postȩpy Dermatologii i Alergologii
Beáta Hutyrová, Jaromír Bystroň
Introduction: Omalizumab is indicated for the treatment of severe allergic asthma (SAA) and chronic spontaneous urticaria, although a number of studies have confirmed the effectiveness of this therapy also for other IgE-mediated diseases. Aim: To assess the impact of anti-IgE therapy on SAA and comorbid IgE-mediated allergic diseases in patients treated with omalizumab for SAA enrolled in the CAR (Czech Anti-IgE Registry). Material and methods: Three hundred and ten patients with SAA treated with omalizumab were enrolled in the CAR...
October 2018: Postȩpy Dermatologii i Alergologii
Anna Michalska-Bańkowska, Dominika Wcisło-Dziadecka, Beniamin Grabarek, Ligia Brzezińska-Wcisło, Urszula Mazurek, Natalia Salwowska, Mirosław Bańkowski
Introduction: Psoriasis is a chronic, immunologic, multi-factor inflammatory skin disease, strongly associated with a higher level of a number of cytokines, such as isoforms of transforming growth factor β (TGF-β1-3) and its receptors (TGF-βRI-III). One of the most popular and important drugs used to treat this disease is cyclosporin A (CsA). Aim: The aim of this study was to investigate the expression of genes encoding the transforming growth factor (TGF)-β isoforms and receptors of the cytokine TGF-βRs in psoriatic patients during an 84-day long observation of the effects of cyclosporin A therapy...
October 2018: Postȩpy Dermatologii i Alergologii
Mustafa Aksoy, Hakim Çelik
Introduction: Vitiligo is an acquired depigmentation disorder with melanocyte destruction. Aim: To examine the thiol/disulphide balance in vitiligo patients and to compare the results with a healthy control group. Material and methods: Thirty-two patients with vitiligo and 35 healthy individuals were included in the study. Native thiol, disulfide and total thiol levels in plasma were evaluated using a new and automated spectrophotometric method...
October 2018: Postȩpy Dermatologii i Alergologii
Krzysztof Pałgan, Magdalena Żbikowska-Götz, Kinga Lis, Elżbieta Chrzaniecka, Zbigniew Bartuzi
Introduction: Asthma is a multiphenotypic disease, and therapeutic managenment in patients with severe asthma is particulary difficult, with conventional treatment of severe asthma showing poor efficacy. Aim: To analyse forced expiratory volume in 1 s (FEV1 ) following the adminstration of omalizumab. Material and methods: Six patinents (mean age: 50 ±12.6) with severe, uncontrolled asthma according to the GINA guidelines were enrolled in the study...
October 2018: Postȩpy Dermatologii i Alergologii
Anna Moniuszko-Malinowska, Piotr Czupryna, Justyna Dunaj, Sławomir Pancewicz, Adam Garkowski, Maciej Kondrusik, Sambor Grygorczuk, Joanna Zajkowska
Introduction: Acrodermatitis chronica atrophicans (ACA) is probably the most common late and chronic manifestation of the Lyme borreliosis seen in European patients. Aim: To analyze epidemiological data, and to investigate the effects of treatment of patients with ACA. Material and methods: Nine patients were included in the study. All patients had serological examinations (ELISA and Western blot) and histopathological examination of the skin lesions performed...
October 2018: Postȩpy Dermatologii i Alergologii
Joanna Salomon, Łukasz Matusiak, Danuta Nowicka-Suszko, Jacek C Szepietowski
Introduction: Psoriasis is an inflammatory disease of a complex pathogenesis and arthritis is one of its most common complications. The biological role of chitinase-3-like protein 1 remains unknown. It is suggested that this protein takes part in processes such as proliferation, inflammation and tissue remodelling. Aim: To determine whether YKL-40 can be a useful biomarker in psoriatic arthritis. Material and methods: The study was performed on 42 patients with psoriatic arthritis: 28 men and 14 women, aged from 24 to 71 years...
October 2018: Postȩpy Dermatologii i Alergologii
Maciej Pastuszczak, Monika Bociąga-Jasik, Marek Sitko, Anna Wojas-Pelc
Introduction: Recent outbreaks of syphilis occurred predominantly in men who have sex with men (MSM). A significant proportion of syphilis cases occur in MSM who had more than one episode of syphilis. This group may play an important role in syphilis transmission. Aim: To identify factors associated with the risk of syphilis reinfection. Material and methods: Forty-four MSM patients with the first episode of syphilis who were treated at the Department of Dermatology at the Jagiellonian University School of Medicine in Krakow, Poland were included in this study...
October 2018: Postȩpy Dermatologii i Alergologii
Agnieszka Cegielska, Katarzyna A Lisowska, Alicja Dębska-Ślizień, Beata Imko-Walczuk, Aleksandra Okuniewska, Bolesław Rutkowski
Introduction: Immunosuppressive therapy, necessary for graft survival, has its clinical consequences with an increased risk of developing malignancies being one of them. It seems that the maintenance of a proper balance between cytotoxic and regulatory activity of the immune system may prevent graft rejection, and with a lower risk of cancer. Aim: To assess the quantitative changes in regulatory T cells (Tregs) in peripheral blood of kidney transplant recipients with post-transplantation skin neoplasm after conversion to mTOR inhibitors (mTORi) and to assess the incidence of secondary skin cancer in that group of patients...
October 2018: Postȩpy Dermatologii i Alergologii
Aleksandra Dańczak-Pazdrowska, Adriana Polańska, Joanna Synakiewicz, Edyta Gurgul, Marta Molińska-Glura, Marek Ruchała, Ryszard Żaba, Zygmunt Adamski
Introduction: Morphea, also known as localized scleroderma, is an autoimmune skin disease which is characterized by excessive accumulation of collagen that leads to the thickening of the dermis and subcutaneous tissue. There is an unclear relationship between morphea and other autoimmune diseases, especially related to the thyroid gland. Aim: To determine the occurrence of increased antithyroid antibodies in patients with morphea in relation to the clinical manifestations of the disease...
October 2018: Postȩpy Dermatologii i Alergologii
Magdalena Paplińska-Goryca, Elżbieta M Grabczak, Marta Dąbrowska, Joanna Hermanowicz-Salamon, Małgorzata Proboszcz, Patrycja Nejman-Gryz, Marta Maskey-Warzęchowska, Rafał Krenke
Introduction: Interleukin 25 is an epithelial-derived cytokine associated with allergic Th2 inflammation. However, little is known about the role of IL-25 in different asthma phenotypes and its relationship with disease severity. Aim: To evaluate and compare the mRNA and protein expression of IL-25 in patients with mild-to moderate/severe asthma and cough variant asthma (CVA). Material and methods: Thirty-eight patients with stable asthma (11 patients with mild-to-moderate asthma, 14 patients with severe asthma and 13 patients with CVA) and 14 control subjects were enrolled...
October 2018: Postȩpy Dermatologii i Alergologii
Patrycja Dolibog, Paweł T Dolibog, Andrzej Franek, Ligia Brzezińska-Wcisło, Beata Wróbel, Hubert Arasiewicz, Daria Chmielewska, Jacek Ziaja, Edward Błaszczak
Introduction: Venous insufficiency and venous leg ulcers each year affect more and more people, especially in developed countries. The challenge of our time is to find an effective method of treating venous leg ulcers, which will further shorten treatment time and reduce the cost of treatment. Aim: To compare the effects of treating venous leg ulcers using ultrasound therapy, radial shock wave therapy and standard care. Material and methods: Group A consisted of 17 patients...
October 2018: Postȩpy Dermatologii i Alergologii
Alessandra Latini, Carlo Cota, Diego Orsini, Antonio Cristaudo, Marinella Tedesco
Introduction: Lichen sclerosus (LS) is a chronic inflammatory disease affecting mainly the genital mucous membranes in both sexes. In the past, different terms were used to describe the disease, rendering a unique and specific clinical classification impossible. Aim: New therapeutic approaches are being defined, which may contribute to a proper clinical management, however, a stage classification is essential to better define appropriate treatment for every stage of the disease...
October 2018: Postȩpy Dermatologii i Alergologii
Kamila Tokarska, Sławomir Tokarski, Anna Woźniacka, Anna Sysa-Jędrzejowska, Jarosław Bogaczewicz
Cellulite (also known as gynoid lipodystrophy or orange peel syndrome) is one of the most common lipodystrophy syndromes, which affects millions of post-adolescent women. Cellulite is manifested by topographic disorders of subcutaneous tissue such as nodules, edema, and abnormal fibrosis. It is located mainly on the pelvic area, especially on the buttocks. Its pathogenesis is complexed and unclear. There are several theories about its pathophysiology. Hormonal disorders, endothelial dysfunction and genetic predispositions are taken under consideration...
October 2018: Postȩpy Dermatologii i Alergologii
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