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Infectious Diseases of Poverty

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https://www.readbyqxmd.com/read/28238285/urogenital-schistosomiasis-and-soil-transmitted-helminthiasis-sth-in-cameroon-an-epidemiological-update-at-barombi-mbo-and-barombi-kotto-crater-lakes-assessing-prospects-for-intensified-control-interventions
#1
Suzy J Campbell, J Russell Stothard, Faye O'Halloran, Deborah Sankey, Timothy Durant, Dieudonné Eloundou Ombede, Gwladys Djomkam Chuinteu, Bonnie L Webster, Lucas Cunningham, E James LaCourse, Louis-Albert Tchuem-Tchuenté
BACKGROUND: The crater lakes of Barombi Mbo and Barombi Kotto are well-known transmission foci of schistosomiasis and soil-transmitted helminthiasis having had several important control initiatives previously. To collect contemporary epidemiological information, a cross-sectional survey was undertaken inclusive of: signs and symptoms of disease, individual treatment histories, local water, sanitation and hygiene (WASH)-related factors and malacological surveillance, with molecular characterisation of specimens...
February 27, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28222792/seroprevalence-of-hepatitis-b-hepatitis-c-human-immunodeficiency-virus-treponema-pallidum-and-co-infections-among-blood-donors-in-kyrgyzstan-a-retrospective-analysis-2013-2015
#2
Bakyt B Karabaev, Nurgul J Beisheeva, Aiganysh B Satybaldieva, Aikul D Ismailova, Frank Pessler, Manas K Akmatov
BACKGROUND: Post-Soviet Kyrgyzstan has experienced a major surge in blood-borne infections, but data from adequately powered, up-to-date studies are lacking. We thus examined a) the seroprevalences of hepatitis B virus surface antigen (HBsAg), HIV-1 p24 antigen and antibodies against hepatitis C virus (anti-HCV), human immunodeficiency viruses (anti-HIV-1/2, HIV-1 group O), and Treponema pallidum among blood donors in Kyrgyzstan and assess their distribution according to sex, age, and provinces of residence; b) trends in the respective seroprevalences; and c) co-infection rates among the pathogens studied...
February 21, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28219411/using-the-hierarchical-ordinal-regression-model-to-analyse-the-intensity-of-urinary-schistosomiasis-infection-in-school-children-in-lusaka-province-zambia
#3
Christopher Simoonga, Lawrence N Kazembe
BACKGROUND: Urinary schistosomiasis has been a major public health problem in Zambia for many years. However, the disease profile may vary in different locale due to the changing ecosystem that contributes to the risk of acquiring the disease. The objective of this study was to quantify risk factors associated with the intensity of urinary schistosomiasis infection in school children in Lusaka Province, Zambia, in order to better understand local transmission. METHODS: Data were obtained from 1 912 school children, in 20 communities, in the districts of Luangwa and Kafue in Lusaka Province...
February 21, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28219418/new-insights-on-serodiagnosis-of-trichinellosis-during-window-period-early-diagnostic-antigens-from-trichinella-spiralis-intestinal-worms
#4
Zhong-Quan Wang, Ya-Li Shi, Rou-Dan Liu, Peng Jiang, Ya-Yi Guan, Ying-Dan Chen, Jing Cui
The clinical diagnosis of trichinellosis is difficult because its clinical manifestations are nonspecific. Detection of anti-Trichinella IgG by ELISA using T. spiralis muscle larval excretory-secretory (ES) antigens is the most commonly used serological method for diagnosis of trichinellosis, but the main disadvantage is false negativity during the early stage of infection. There is an obvious window period between Trichinella infection and antibody positivity.During the intestinal stage of Trichinella infection, the ES antigens of intestinal worms (intestinal infective larvae and adults) are exposed to host's immune system at the earliest time and elicit the production of specific anti-Trichinella antibodies...
February 20, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28219412/moving-from-control-to-elimination-of-schistosomiasis-in-sub-saharan-africa-time-to-change-and-adapt-strategies
#5
REVIEW
Louis-Albert Tchuem Tchuenté, David Rollinson, J Russell Stothard, David Molyneux
Schistosomiasis is a water borne parasitic disease of global importance and with ongoing control the disease endemic landscape is changing. In sub-Saharan Africa, for example, the landscape is becoming ever more heterogeneous as there are several species of Schistosoma that respond in different ways to ongoing preventive chemotherapy and the inter-sectoral interventions currently applied. The major focus of preventive chemotherapy is delivery of praziquantel by mass drug administration to those shown to be, or presumed to be, at-risk of infection and disease...
February 20, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28209208/food-safety-in-vietnam-where-we-are-at-and-what-we-can-learn-from-international-experiences
#6
Hung Nguyen-Viet, Tran Thi Tuyet-Hanh, Fred Unger, Sinh Dang-Xuan, Delia Grace
Food-borne diseases are attracting a lot of attention in Vietnam as a result of repeated episodes of adulterated and unsafe food. In this paper, we provide some perspectives on food safety in Vietnam from the point of view of an international research institution working on food safety with partners in the country. We argue that one of the key issues of food safety in Vietnam is that certain food value chain stakeholders lack ethics, which leads to the production and trading of unsafe foods in order to make profits irrespective of adverse health effects on consumers...
February 16, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28196511/antiretroviral-therapy-related-adverse-effects-can-sub-saharan-africa-cope-with-the-new-test-and-treat-policy-of-the-world-health-organization
#7
Jobert Richie N Nansseu, Jean Joel R Bigna
BACKGROUND: Recent studies have shown that early antiretroviral therapy (ART) initiation results in significant HIV transmission reduction. This is the rationale behind the "test and treat" policy of the World Health Organization (WHO). Implementation of this policy will lead to an increased incidence of ART-related adverse effects, especially in sub-Saharan Africa (SSA). Is the region yet ready to cope with such a challenging issue? MAIN BODY: The introduction and widespread use of ART have drastically changed the natural history of HIV/AIDS, but exposure to ART leads to serious medication-related adverse effects mainly explained by mitochondrial toxicities, and the situation will get worse in the near future...
February 15, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28190399/a-community-based-survey-of-toxoplasma-gondii-infection-among-pregnant-women-in-rural-areas-of-taiz-governorate-yemen-the-risk-of-waterborne-transmission
#8
Mohammed A K Mahdy, Lina M Q Alareqi, Rashad Abdul-Ghani, Samira M A Al-Eryani, Abdullah A Al-Mikhlafy, Abdulsalam M Al-Mekhlafi, Fawzya Alkarshy, Rohela Mahmud
BACKGROUND: Toxoplasma gondii is a zoonotic coccidian parasite causing morbidity and mortality. In Yemen, T. gondii infection has been reported among pregnant women seeking healthcare in the main cities. However, no data are available on the prevalence of T. gondii infection and its associated risk factors among pregnant women in the rural communities of the country. Thus, the present study aimed to determine the seroprevalence of T. gondii and identify its risk factors among pregnant women in the rural communities of Taiz governorate, Yemen...
February 13, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28187780/levels-of-insecticide-resistance-to-deltamethrin-malathion-and-temephos-and-associated-mechanisms-in-aedes-aegypti-mosquitoes-from-the-guadeloupe-and-saint-martin-islands-french-west-indies
#9
Daniella Goindin, Christelle Delannay, Andric Gelasse, Cédric Ramdini, Thierry Gaude, Frédéric Faucon, Jean-Philippe David, Joël Gustave, Anubis Vega-Rua, Florence Fouque
BACKGROUND: In the Guadeloupe and Saint Martin islands, Aedes aegypti mosquitoes are the only recognized vectors of dengue, chikungunya, and Zika viruses. For around 40 years, malathion was used as a mosquito adulticide and temephos as a larvicide. Since the European Union banned the use of these two insecticide molecules in the first decade of the 21st century, deltamethrin and Bacillus thuringiensis var. israelensis are the remaining adulticide and larvicide, respectively, used in Guadeloupe...
February 10, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28179024/impact-of-single-annual-treatment-and-four-monthly-treatment-for-hookworm-and-ascaris-lumbricoides-and-factors-associated-with-residual-infection-among-kenyan-school-children
#10
RANDOMIZED CONTROLLED TRIAL
Stella Kepha, Charles S Mwandawiro, Roy M Anderson, Rachel L Pullan, Fred Nuwaha, Jorge Cano, Sammy M Njenga, Maurice R Odiere, Elizabeth Allen, Simon J Brooker, Birgit Nikolay
BACKGROUND: School-based deworming is widely implemented in various countries to reduce the burden of soil-transmitted helminths (STHs), however, the frequency of drug administration varies in different settings. In this study, we compared the impact of a single annual treatment and 4-monthly treatment over a follow-up among Kenyan school children, and investigated the factors associated with residual infection. METHODS: We performed a secondary analysis of data from a randomized trial investigating whether deworming for STHs alters risk of acquiring malaria...
February 9, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28179020/hepatitis-b-virus-infection-in-undocumented-immigrants-and-refugees-in-southern-italy-demographic-virological-and-clinical-features
#11
MULTICENTER STUDY
Nicola Coppola, Loredana Alessio, Luciano Gualdieri, Mariantonietta Pisaturo, Caterina Sagnelli, Carmine Minichini, Giovanni Di Caprio, Mario Starace, Lorenzo Onorato, Giuseppe Signoriello, Margherita Macera, Italo Francesco Angelillo, Giuseppe Pasquale, Evangelista Sagnelli
BACKGROUND: The data on hepatitis b virus (HBV) infection in immigrants population are scanty. The porpoise of this study was to define the demographic, virological, and clinical characteristics of subjects infected with HBV chronic infection in a cohort of immigrants living in Naples, Italy. METHODS: A screening for HBV infection was offered to 1,331 immigrants, of whom 1,212 (91%) (831 undocumented immigrants and 381 refugees) accepted and were screened for hepatitis B surface antigen (HBsAg) and anti-hepatitis B core antibody (HBc)...
February 9, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28173858/mortality-trends-for-neglected-tropical-diseases-in-the-state-of-sergipe-brazil-1980-2013
#12
Marcos Antônio Costa de Albuquerque, Danielle Menezes Dias, Lucas Teixeira Vieira, Carlos Anselmo Lima, Angela Maria da Silva
BACKGROUND: Neglected Tropical Diseases are a set of communicable diseases that affect the population so low socioeconomic status, particularly 1.4 billion people who are living below the poverty level. This study has investigated the magnitude and mortality time trends for these diseases in the state of Sergipe, Northeast Region of Brazil. METHODS: We conducted an ecological study of time series, based on secondary data derived from the Mortality Information System of the Ministry of Health...
February 8, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28173839/characterisation-of-larval-habitats-species-composition-and-factors-associated-with-the-seasonal-abundance-of-mosquito-fauna-in-gezira-sudan
#13
Mostafa M Mahgoub, Eliningaya J Kweka, Yousif E Himeidan
BACKGROUND: Larval source management (LSM), which requires an understanding of the ecology and composition of the local mosquito fauna, is an important parameter in successful vector control programmes. The present study was conducted to understand the distribution of larval habitats, species composition and factors associated with the seasonal abundance of mosquito larvae in Gezira irrigation Scheme in Gezira state, central Sudan. METHODS: Cross-sectional larval surveys were carried out in the communities of Barakat (urban) and El-Kareiba (semi-urban), in Wad Madani, Gezira...
February 8, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28173857/understanding-the-strategies-employed-to-cope-with-increased-numbers-of-aids-orphaned-children-in-families-in-rural-settings-a-case-of-mbeya-rural-district-tanzania
#14
Nelsensius Klau Fauk, Silivano Edson Mwakinyali, Sukma Putra, Lillian Mwanri
BACKGROUND: The purpose of this study was to understand the strategies employed by families that adopt Acquired Immune Deficiency Syndrome (AIDS)-orphaned children (Adoptive families) for coping with and mitigating the impact of AIDS in Mbeya Rural District, Tanzania. High numbers of AIDS-orphaned children aged below 18 years in Mbeya Region have led to increasing the burden of families caring for them. Understanding the coping strategies and impact mitigation activities employed by adoptive families is important in order to develop programmes to help them...
February 7, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28173853/therapeutic-efficacy-and-effects-of-artemisinin-based-combination-treatments-on-uncomplicated-plasmodium-falciparum%C3%A2-malaria-associated-anaemia-in-nigerian-children-during-seven-years-of-adoption-as-first-line-treatments
#15
Akintunde Sowunmi, Kazeem Akano, Godwin Ntadom, Adejumoke I Ayede, Folasade O Ibironke, Temitope Aderoyeje, Elsie O Adewoye, Bayo Fatunmbi, Stephen Oguche, Henrietta U Okafor, Ismaila Watila, Martin Meremikwu, Philip Agomo, William Ogala, Chimere Agomo, Onikepe A Folarin, Grace O Gbotosho, Christian T Happi
BACKGROUND: Artemisinin-based combination treatments (ACTs) are the first-line treatments of uncomplicated Plasmodium falciparum malaria in many endemic areas but there are few evaluation of their efficacy in anaemic malarious children. METHODS: Therapeutic efficacy of 3-day regimens of artesunate-amodiaquine and artemether-lumefantrine was evaluated in 437 anaemic and 909 non-anaemic malarious children following treatment during a seven-year period (2008-2014)...
February 7, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28166826/socio-ecological-dynamics-and-challenges-to-the-governance-of-neglected-tropical-disease-control
#16
REVIEW
Edwin Michael, Shirin Madon
The current global attempts to control the so-called "Neglected Tropical Diseases (NTDs)" have the potential to significantly reduce the morbidity suffered by some of the world's poorest communities. However, the governance of these control programmes is driven by a managerial rationality that assumes predictability of proposed interventions, and which thus primarily seeks to improve the cost-effectiveness of implementation by measuring performance in terms of pre-determined outputs. Here, we argue that this approach has reinforced the narrow normal-science model for controlling parasitic diseases, and in doing so fails to address the complex dynamics, uncertainty and socio-ecological context-specificity that invariably underlie parasite transmission...
February 6, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28166813/hidden-reservoir-of-resistant-parasites-the-missing-link-in-the-elimination-of-falciparum-malaria
#17
Rashad Abdul-Ghani, Mohammed A K Mahdy, John C Beier, Leonardo K Basco
BACKGROUND: To successfully eliminate malaria, an integrated system that includes a number of approaches and interventions-aimed at overcoming the threat of antimalarial drug resistance-is required. Significant progress has been made in reducing malaria incidence through large-scale use of artemisinin-based combination therapies and insecticide-treated nets. To consolidate these gains, attention should be paid to the missing links in the elimination of malaria. One of these gaps is the residual reservoir of submicroscopic resistant parasites, which remains after case management or other control measures have been carried out...
February 6, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28162096/intestinal-schistosomiasis-in-uganda-at-high-altitude-1400%C3%A2-m-malacological-and-epidemiological-surveys-on-mount-elgon-and-in-fort-portal-crater-lakes-reveal-extra-preventive-chemotherapy-needs
#18
Michelle C Stanton, Moses Adriko, Moses Arinaitwe, Alison Howell, Juliet Davies, Gillian Allison, E James LaCourse, Edridah Muheki, Narcis B Kabatereine, J Russell Stothard
BACKGROUND: Intestinal schistosomiasis is of public health importance in Uganda but communities living above 1400 m are not targeted for control as natural transmission is thought unlikely. To assess altitudinal boundaries and at-risk populations, conjoint malacological and epidemiological surveys were undertaken on Mount Elgon (1139 m-3937 m), in Fort Portal crater lakes and in the Rwenzori Mountains (1123 m-4050 m). METHODS: Seventy freshwater habitats [Mount Elgon (37), Fort Portal crater lakes (23), Rwenzori Mountains (8) and Lake Albert (2)] were inspected for Biomphalaria species...
February 6, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28162095/hepatitis-e-infection-among-ghanaians-a-systematic-review
#19
REVIEW
Richard Ofori-Asenso, Akosua Adom Agyeman
BACKGROUND: Hepatitis E virus (HEV) infection is considered to be of significant public health importance in many developing countries. In this review, we aim to summarise studies on HEV with the aim of providing a further understanding of the epidemiology of the disease in Ghana. METHODS: A systematic review was conducted by following the recommendations outlined in the PRISMA statement. Studies on HEV infection among Ghanaians were identified by searching for articles (published up until 4th August 2016) in the PubMed, ISI Web of Science, African Journals Online, Google Scholar and the WHO African Index Medicus databases...
February 6, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28162093/evaluating-the-impact-of-targeting-livestock-for-the-prevention-of-human-and-animal-trypanosomiasis-at-village-level-in-districts-newly-affected-with-t-b-rhodesiense-in-uganda
#20
Louise Hamill, Kim Picozzi, Jenna Fyfe, Beatrix von Wissmann, Sally Wastling, Nicola Wardrop, Richard Selby, Christine Amongi Acup, Kevin L Bardosh, Dennis Muhanguzi, John D Kabasa, Charles Waiswa, Susan C Welburn
BACKGROUND: Uganda has suffered from a series of epidemics of Human African Trypanosomiasis (HAT), a tsetse transmitted disease, also known as sleeping sickness. The area affected by acute Trypanosoma brucei rhodesiense HAT (rHAT) has been expanding, driven by importation of infected cattle into regions previously free of the disease. These regions are also affected by African Animal Trypanosomiasis (AAT) demanding a strategy for integrated disease control. METHODS: In 2008, the Public Private Partnership, Stamp Out Sleeping Sickness (SOS) administered a single dose of trypanocide to 31 486 head of cattle in 29 parishes in Dokolo and Kaberamaido districts...
February 6, 2017: Infectious Diseases of Poverty
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