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Infectious Diseases of Poverty

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https://www.readbyqxmd.com/read/29137664/therapeutic-efficacy-of-artemether-lumefantrine-in-the-treatment-of-uncomplicated-plasmodium-falciparum-malaria-in-ethiopia-a-systematic-review-and-meta-analysis
#1
REVIEW
Mohammed Biset Ayalew
BACKGROUND: As Ethiopia is one of the sub-Saharan countries with a great burden of malaria the effectiveness of first line anti-malarial drugs is the major concern. The aim of this study was to synthesize the available evidence on the efficacy of artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Ethiopia. This was done by performing a meta-analysis of recent studies conducted in the country on this topic. METHODS: Studies published between January 2010 and January 2017 that reported on the efficacy of artemether-lumefantrine in the treatment of P...
November 15, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29137661/applying-tuberculosis-management-time-to-measure-the-tuberculosis-infectious-pool-at-a-local-level-in-ethiopia
#2
Senedu Bekele Gebreegziabher, Gunnar Aksel Bjune, Solomon Abebe Yimer
BACKGROUND: Measuring the size of the infectious pool of tuberculosis (TB) is essential to understand the burden and monitor trends of TB control program performance. This study applied the concept of TB management time to estimate and compare the size of the TB infectious pool between 2009 and 2014 in West Gojjam Zone of Amhara Region, Ethiopia. METHODS: New sputum smear-positive and smear-negative pulmonary TB (PTB) and retreatment cases who attended 30 randomly selected public health facilities in West Gojjam Zone from October 2013 to October 2014 were consecutively enrolled in the study...
November 15, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29110719/plague-risk-in-vulnerable-community-assessment-of-xenopsylla-cheopis-susceptibility-to-insecticides-in-malagasy-prisons
#3
Adélaïde Miarinjara, Jean Vergain, Jean Marcel Kavaruganda, Minoarisoa Rajerison, Sébastien Boyer
BACKGROUND: Prisons in Madagascar are at high risk of plague outbreak. Occurrence of plague epidemic in prisons can cause significant episode of urban plague through the movement of potentially infected humans, rodents and fleas. Rodent and flea controls are essential in plague prevention, by reducing human contact with plague reservoirs and vectors. Insecticide treatment is the key step available for the control of rat fleas which transmit the disease from infected rodents to human. The implementation of an adapted flea control strategy should rely on the insecticide susceptibility status of the targeted population...
November 7, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29110734/socioeconomic-and-behavioural-determinants-of-malaria-among-the-migrants-in-gold-mining-rubber-and-oil-palm-plantation-areas-in-myanmar
#4
Htin Zaw Soe, Aung Thi, Ni Ni Aye
BACKGROUND: Malaria is a major public health problem in Myanmar. Migrant populations are at high risk of contracting malaria and its control is more difficult than for settled population. Studies on malaria and migration are rare in Myanmar. This study was undertaken with the main objective of identifying socioeconomic and behavioural determinants of malaria among the migrant workers involved in gold mining, rubber and oil palm plantations. METHODS: A cross-sectional analytic study was conducted using pretested interview-administered questionnaires among internal migrants (n = 406) in the malaria endemic townships of Shwegyin, Bago Region, Thanbyuzayat, Mon State and Kawthaung, Taninthayi Region from August to November, 2015...
November 6, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29110722/molecular-markers-for-artemisinin-and-partner-drug-resistance-in-natural-plasmodium-falciparum-populations-following-increased-insecticide-treated-net-coverage-along-the-slope-of-mount-cameroon-cross-sectional-study
#5
Tobias O Apinjoh, Regina N Mugri, Olivo Miotto, Hanesh F Chi, Rolland B Tata, Judith K Anchang-Kimbi, Eleanor M Fon, Delphine A Tangoh, Robert V Nyingchu, Christopher Jacob, Roberto Amato, Abdoulaye Djimde, Dominic Kwiatkowski, Eric A Achidi, Alfred Amambua-Ngwa
BACKGROUND: Drug resistance is one of the greatest challenges of malaria control programmes, with the monitoring of parasite resistance to artemisinins or to Artemisinin Combination Therapy (ACT) partner drugs critical to elimination efforts. Markers of resistance to a wide panel of antimalarials were assessed in natural parasite populations from southwestern Cameroon. METHODS: Individuals with asymptomatic parasitaemia or uncomplicated malaria were enrolled through cross-sectional surveys from May 2013 to March 2014 along the slope of mount Cameroon...
November 6, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29096720/neglected-tropical-diseases-in-brazilian-children-and-adolescents-data-analysis-from-2009-to-2013
#6
Eduardo Brandão, Sebastián Romero, Maria Almerice Lopes da Silva, Fred Luciano Neves Santos
BACKGROUND: Neglected tropical diseases (NTDs) prevail in conditions of poverty and contribute to the maintenance of social inequality. Out of the NTDs prioritized by the Brazilian Ministry of Health, four parasitic infections require mandatory notification: acute Chagas disease, leishmaniasis, malaria, and schistosomiasis. Data on the behaviour of these NTDs in the young population are currently limited. This study seeks to analyse the epidemiological aspects of these parasitic infections in children and adolescents in Brazil...
November 3, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29092717/routinely-detected-indicators-in-plasma-have-a-predictive-effect-on-the-identification-of-hiv-infected-patients-with-non-tuberculous-mycobacterial-and-tuberculous-infections
#7
Ren-Tian Cai, Feng-Xue Yu, Zhen Tao, Xue-Qin Qian, Jun Chen, Hong-Zhou Lu
BACKGROUND: It is difficult to quickly distinguish non-tuberculous mycobacterial (NTM) infection from tuberculosis (TB) infection in human immunodeficiency virus (HIV)-infected patients because of many similarities between these diseases. A simple and effective way to determine the differences using routine blood tests is necessary in developing countries. METHODS: A retrospective cohort study was conducted to recruit HIV-infected patients with either NTM infection or TB infection diagnosed for the first time according to mycobacterial culture and microscopic identification from May 2010 to March 2016...
November 2, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29089064/utilizing-the-ultrasensitive-schistosoma-up-converting-phosphor-lateral-flow-circulating-anodic-antigen-ucp-lf-caa-assay-for-sample-pooling-strategies
#8
Paul L A M Corstjens, Pytsje T Hoekstra, Claudia J de Dood, Govert J van Dam
BACKGROUND: Methodological applications of the high sensitivity genus-specific Schistosoma CAA strip test, allowing detection of single worm active infections (ultimate sensitivity), are discussed for efficient utilization in sample pooling strategies. Besides relevant cost reduction, pooling of samples rather than individual testing can provide valuable data for large scale mapping, surveillance, and monitoring. METHOD: The laboratory-based CAA strip test utilizes luminescent quantitative up-converting phosphor (UCP) reporter particles and a rapid user-friendly lateral flow (LF) assay format...
November 1, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29065914/seroprevalence-of-toxoplasma-gondii-infection-in-arthritis-patients-in-eastern-china
#9
Ai-Ling Tian, Yuan-Lin Gu, Na Zhou, Wei Cong, Guang-Xing Li, Hany M Elsheikha, Xing-Quan Zhu
BACKGROUND: There is accumulating evidence for an increased susceptibility to infection in patients with arthritis. We sought to understand the epidemiology of Toxoplasma gondii infection in arthritis patients in eastern China, given the paucity of data on the magnitude of T. gondii infection in these patients. METHODS: Seroprevalence of T. gondii infection was assessed by enzyme-linked immunosorbent assay using a crude antigen of the parasite in 820 arthritic patients, and an equal number of healthy controls, from Qingdao and Weihai cities, eastern China...
October 25, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29032768/molluscicidal-effect-of-achyranthes-aspera-l-amaranthaceae-aqueous-extract-on-adult-snails-of-biomphalaria-pfeifferi-and-lymnaea-natalensis
#10
Belayhun Mandefro, Seid Tiku Mereta, Yinebeb Tariku, Argaw Ambelu
BACKGROUND: Intestinal schistosomiasis caused by Schistosoma mansoni is a wide spread disease in most parts of Ethiopian highlands. Snail control is one major strategy in schistosomiasis control. The use of molluscicidal plant products is becoming interesting due to their environmental friendliness, accessibility and easy application. This research is aimed to evaluate the molluscicidal effect of Achyranthes aspera on Biomphalaria pfeifferi and Lymnaea natalensis snails, which are of great medical and veterinary importance in Ethiopia...
October 16, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29020981/areas-with-evidence-of-equity-and-their-progress-on-mortality-from-tuberculosis-in-an-endemic-municipality-of-southeast-brazil
#11
Mellina Yamamura, Marcelino Santos Neto, Francisco Chiaravalloti Neto, Luiz Henrique Arroyo, Antônio Carlos Vieira Ramos, Ana Angélica Rêgo de Queiroz, Aylana de Souza Belchior, Danielle Talita Dos Santos, Juliane de Almeida Crispim, Ione Carvalho Pinto, Severina Alice da Costa Uchôa, Regina Célia Fiorati, Ricardo Alexandre Arcêncio
BACKGROUND: In Brazil, people still fall ill and die from tuberculosis (TB), and this can be explained by the significant impasse in the equity of distribution of therapeutic resources to the population as a whole. The aim was to identify geographical areas which have shown progress in terms of equity (of income, schooling and urban occupancy) and test its effect on mortality from TB in a municipality of southeast Brazil. METHODS: It is an ecological study considering TB as the basic cause for deaths registered between 2006 and 2013 on the Mortality Information System and other variables obtained through the Demographic Census of the Brazilian Institute of Geography and Statistics (2010)...
October 12, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29017610/hiv-among-people-who-inject-drugs-in-hungary
#12
András Ortutay, V Anna Gyarmathy, Zsuzsa Marjanek, Károly Nagy, József Rácz, István Barcs
BACKGROUND: Before 2014 (the year of closure of the two largest needle exchange programs in Hungary, which halved the number of available syringes in the country despite increased injecting risk practices) no HIV was reportedly acquired in Hungary among people who inject drugs (PWIDs) who were not also men who had sex with other men (MSM). In 2014, one and in 2015 two non-MSM PWIDs were newly diagnosed with HIV who supposedly became infected in Hungary, and both incident HIV cases in 2015 were diagnosed in the AIDS stage...
October 11, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29017587/the-perspective-of-gender-on-the-ebola-virus-using-a-risk-management-and-population-health-framework-a-scoping-review
#13
REVIEW
Miriam N Nkangu, Oluwasayo A Olatunde, Sanni Yaya
BACKGROUND: In the three decades since the first reported case of Ebola virus, most known index cases have been consistently traced to the hunting of "bush meat", and women have consistently recorded relatively high fatality rates in most catastrophic outbreaks. This paper discusses Ebola-related risk factors, which constantly interact with cultural values, and provides an insight into the link between gender and the risk of contracting infectious diseases, using Ebola virus as an example within Africa...
October 11, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29017597/estimating-the-economic-and-social-consequences-for-patients-diagnosed-with-human-african-trypanosomiasis-in-muchinga-lusaka-and-eastern-provinces-of-zambia-2004-2014
#14
Allan Mayaba Mwiinde, Martin Simuunza, Boniface Namangala, Chitalu Miriam Chama-Chiliba, Noreen Machila, Neil Anderson, Alexandra Shaw, Susan C Welburn
BACKGROUND: Acute human African trypanosomiasis (rHAT) caused by Trypanosoma brucei rhodesiense is associated with high mortality and is fatal if left untreated. Only a few studies have examined the psychological, social and economic impacts of rHAT. In this study, mixed qualitative and quantitative research methods were used to evaluate the socio-economic impacts of rHAT in Mambwe, Rufunsa, Mpika and Chama Districts of Zambia. METHODS: Individuals diagnosed with rHAT from 2004 to 2014 were traced using hospital records and discussions with communities...
October 10, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28992811/cholera-outbreak-caused-by-drinking-lake-water-contaminated-with-human-faeces-in-kaiso-village-hoima-district-western-uganda-october-2015
#15
David W Oguttu, A Okullo, G Bwire, P Nsubuga, A R Ario
BACKGROUND: On 12 October 2015, a cholera outbreak involving 65 cases and two deaths was reported in a fishing village in Hoima District, Western Uganda. Despite initial response by the local health department, the outbreak persisted. We conducted an investigation to identify the source and mode of transmission, and recommend evidence-led interventions to control and prevent cholera outbreaks in this area. METHODS: We defined a suspected case as the onset of acute watery diarrhoea from 1 October to 2 November 2015 in a resident of Kaiso Village...
October 10, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28988540/the-burden-of-and-risk-factors-for-active-trachoma-in-the-north-and-south-wollo-zones-of-amhara-region-ethiopia-a-cross-sectional-study
#16
Beselam Tadesse, Alemayehu Worku, Abera Kumie, Solomon Abebe Yimer
BACKGROUND: Trachoma is a disease of the eye, caused by the bacteria Chlamydia trachomatis, which can lead to blindness if left untreated. Ethiopia is one of the most trachoma-affected countries in the world. The objective of this study was to determine the prevalence of and associated risk factors for active trachoma among children in selected woredas of North and South Wollo Zones in Amhara Region, Ethiopia. METHODS: This study was a community-based, cross-sectional study, which was conducted from October to December 2014 among children aged 1-8...
October 9, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28988539/prevalence-and-determinants-of-active-trachoma-among-preschool-aged-children-in-dembia-district-northwest-ethiopia
#17
Ayanaw Tsega Ferede, Abel Fekadu Dadi, Amare Tariku, Akilew Awoke Adane
BACKGROUND: Trachoma is an infectious eye disease caused by Chlamydia trachomatis, which is the leading infectious cause of blindness worldwide. In areas where trachoma is endemic, active trachoma is common among preschool-aged children, with varying magnitude. This study aimed to estimate the prevalence of active trachoma and associated risk factors among preschool-aged children in Dembia District, northwest Ethiopia. METHODS: A community-based cross-sectional survey was conducted among preschool-aged children of northwest Ethiopia...
October 9, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28988538/high-prevalence-of-soil-transmitted-helminth-infections-among-primary-school-children-uttar-pradesh-india-2015
#18
Sandipan Ganguly, Sharad Barkataki, Sumallya Karmakar, Prerna Sanga, K Boopathi, K Kanagasabai, P Kamaraj, Punam Chowdhury, Rituparna Sarkar, Dibyendu Raj, Leo James, Shanta Dutta, Rakesh Sehgal, Priya Jha, Manoj Murhekar
BACKGROUND: Soil-transmitted helminth (STH) infections often affect the poorest and most deprived communities. In order to generate reliable data for planning a school based deworming program, we conducted a survey among primary school children studying in government schools in the Indian state of Uttar Pradesh. The objectives of our survey were to estimate the prevalence and intensity of STH infections. METHODS: We conducted a cross-sectional survey among children studying in 130 primary schools from 9 agro-climatic zones, during May - August 2015...
October 9, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28969698/sequencing-and-analysis-of-the-complete-mitochondrial-genome-in-anopheles-sinensis-diptera-culicidae
#19
Kai Chen, Yan Wang, Xiang-Yu Li, Heng Peng, Ya-Jun Ma
BACKGROUND: Anopheles sinensis (Diptera: Culicidae) is a primary vector of Plasmodium vivax and Brugia malayi in most regions of China. In addition, its phylogenetic relationship with the cryptic species of the Hyrcanus Group is complex and remains unresolved. Mitochondrial genome sequences are widely used as molecular markers for phylogenetic studies of mosquito species complexes, of which mitochondrial genome data of An. sinensis is not available. METHODS: An...
October 2, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28965490/study-roadmap-for-high-throughput-development-of-easy-to-use-and-affordable-biomarkers-as-diagnostics-for-tropical-diseases-a-focus-on-malaria-and-schistosomiasis
#20
Kokouvi Kassegne, Ting Zhang, Shen-Bo Chen, Bin Xu, Zhi-Sheng Dang, Wang-Ping Deng, Eniola Michael Abe, Hai-Mo Shen, Wei Hu, Takele Geressu Guyo, Solomon Nwaka, Jun-Hu Chen, Xiao-Nong Zhou
BACKGROUND: Interventions are currently being used against 'infectious diseases of poverty', which remain highly debilitating and deadly in most endemic countries, especially malaria, schistosomiasis, echinococcosis and African sleeping sickness. However, major limitations of current 'traditional' methods for diagnosis are neither simple nor convenient for population surveillance, and showed low sensitivity and specificity. Access to novel technologies for the development of adequate and reliable tools are expressly needed...
October 2, 2017: Infectious Diseases of Poverty
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