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European Heart Journal. Acute Cardiovascular Care

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https://www.readbyqxmd.com/read/28984467/the-9p21-rs-1333040-polymorphism-is-associated-with-coronary-microvascular-obstruction-in-st-segment-elevation-myocardial-infarction-treated-by-primary-angioplasty
#1
Francesco Fracassi, Giampaolo Niccoli, Vincenzo Vetrugno, Michele Cauteruccio, Antonino Buffon, Ilaria Gatto, Igor Giarretta, Paolo Tondi, Roberto Pola, Filippo Crea
BACKGROUND: Microvascular obstruction (MVO) after primary percutaneous coronary intervention (pPCI) leads to higher incidence of both early and late complications. A number of single nucleotide polymorphisms in 9p21 chromosome have been shown to affect angiogenesis in response to ischaemia. In particular, Rs1333040 with its three genotypic vriants C/C, T/C and T/T might influence the occurrence of MVO after pPCI. METHODS: We enrolled ST-elevation myocardial infarction (STEMI) patients undergoing pPCI...
October 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28980483/clinical-outcomes-following-primary-percutaneous-coronary-intervention-for-st-elevation-myocardial-infarction-according-to-sex-and-race
#2
Arvindra Krishnamurthy, Claire Keeble, Natalie Burton-Wood, Kathryn Somers, Michelle Anderson, Charlotte Harland, Paul D Baxter, James M McLenachan, Jonathan M Blaxill, Daniel J Blackman, Christopher J Malkin, Stephen B Wheatcroft, John P Greenwood
BACKGROUND: Female sex and South Asian race have been associated with poor clinical outcomes following primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) but remain understudied in large real-world series. We therefore investigated the association of sex and race with clinical outcomes following PPCI. METHODS: We conducted a prospective study of all patients undergoing PPCI for STEMI between January 2009 and December 2011 at a large UK cardiac centre...
October 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28948850/the-impact-of-airway-strategy-on-the-patient-outcome-after-out-of-hospital-cardiac-arrest-a-propensity-score-matched-analysis
#3
Patrick Sulzgruber, Philip Datler, Fritz Sterz, Michael Poppe, Elisabeth Lobmeyr, Markus Keferböck, Sebastian Zeiner, Alexander Nürnberger, Andreas Schober, Pia Hubner, Peter Stratil, Christian Wallmueller, Christoph Weiser, Alexandra-Maria Warenits, Andreas Zajicek, Florian Ettl, Ingrid Magnet, Thomas Uray, Christoph Testori, Raphael van Tulder
BACKGROUND: While guidelines mentioned supraglottic airway management in the case of out-of- hospital cardiac arrest, robust data of their impact on the patient outcome remain scare and results are inconclusive. METHODS: To assess the impact of the airway strategy on the patient outcome we prospectively enrolled 2224 individuals suffering cardiac arrest who were treated by the Viennese municipal emergency medical service. To control for potential confounders, propensity score matching was performed...
September 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28927294/treatment-of-patients-with-myocardial-infarction-depends-on-history-of-cancer
#4
Sabine Rohrmann, Fabienne Witassek, Paul Erne, Hans Rickli, Dragana Radovanovic
BACKGROUND: Although cancer treatment considerably affects cardiovascular health, little is known about how cancer patients are treated for an acute myocardial infarction. We aimed to investigate whether acute myocardial infarction patients with a history of cancer received the same guideline recommended treatment as those acute myocardial infarction patients without and whether they differ with respect to inhospital outcome. METHODS: All patients with ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction, enrolled between 2002 and mid-2015 in the acute myocardial infarction in Switzerland (AMIS Plus) registry with comorbidity data based on the Charlson comorbidity index were analysed...
September 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28920703/prognostic-usefulness-of-an-age-adapted-equation-for-renal-function-assessment-in-older-patients-with-acute-coronary-syndrome
#5
Lucía Rioboo Lestón, Emad Abu-Assi, Sergio Raposeiras-Roubin, Rafael Cobas-Paz, Berenice Caneiro-Queija, Jose Manuel Rodríguez-Rodríguez, Andres Íñiguez-Romo
BACKGROUND: Renal dysfunction negatively impacts survival in acute coronary syndrome patients. The Berlin Initiative Study creatinine-based (BIScrea) equation has recently been proposed for renal function assessment in older persons. However, up to now it is unknown if the superiority of the new BIScrea equation, with respect to the most recommended chronic kidney disease epidemiology collaboration creatinine-based (CKD-EPIcrea) formula, would translate into better risk prediction of adverse events in older patients with acute coronary syndrome...
September 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28895425/predictors-of-subsequent-myocardial-infarction-stroke-and-death-in-stable-post-myocardial-infarction-patients-a-nationwide-cohort-study
#6
Dong-Yi Chen, Chen-Yu Li, Ming-Jer Hsieh, Chun-Chi Chen, I-Chang Hsieh, Tien-Hsing Chen, Shao-Wei Chen, Chao-Yung Wang, Shang-Hung Chang, Cheng-Hung Lee, Ming-Lung Tsai, Ming-Yun Ho, Jih-Kai Yeh, Chee-Jen Chang, Ming-Shien Wen
BACKGROUND: This study investigated the predictors of subsequent cardiovascular events in stable post-myocardial infarction patients in Taiwan. METHODS: A total of 11,183 patients were recruited who had survived one year post-myocardial infarction without subsequent events of recurrent myocardial infarction or stroke from the Taiwan National Health Insurance Research Database. Their composite cardiovascular event rates were identified. RESULTS: The composite cardiovascular events rate in three year follow-up in the post-myocardial infarction population was 13...
September 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28879778/percutaneous-extracorporeal-membrane-oxygenation-in-electrical-storm-five-case-reports-addressing-efficacy-transferring-allowance-or-radiofrequency-ablation-support
#7
Aitor Uribarri, Loreto Bravo, Javier Jimenez-Candil, Javier Martin-Moreiras, Eduardo Villacorta, Pedro L Sanchez
Extracorporeal membrane oxygenation systems have undergone rapid technological improvements and are now feasible options for medium-term support of severe cardiac or pulmonary failure. We report five cases of electrical storm that was rescued by the insertion of peripheral veno-arterial extracorporeal membrane oxygenation systems. This device could help to restore systemic circulation as well as permitting organ perfusion in patients with cardiogenic shock in relation to electrical storm thus achieving greater electrical stability...
September 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28879773/association-of-admission-and-discharge-anemia-status-with-outcomes-in-patients-hospitalized-for-acute-decompensated-heart-failure-differences-between-patients-with-preserved-and-reduced-ejection-fraction
#8
Katsuya Kajimoto, Yuichiro Minami, Shigeru Otsubo, Naoki Sato
BACKGROUND: In acute decompensated heart failure patients with a preserved or reduced ejection fraction, the association of admission and discharge anemia status with outcomes remains unclear. METHODS AND RESULTS: Of the 4842 patients enrolled in the Acute Decompensated Heart Failure Syndromes (ATTEND) registry, 4433 patients (2017 with a preserved and 2416 with a reduced ejection fraction) were examined to investigate associations among the anemia status at admission and discharge (no anemia, developed anemia, resolved anemia, or persistent anemia), a preserved or reduced ejection fraction and the primary endpoint (all-cause death and readmission for heart failure)...
September 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28868906/therapeutic-application-of-contrast-ultrasound-in-st-elevation-myocardial-infarction-role-in-coronary-thrombosis-and-microvascular-obstruction
#9
Jeroen Slikkerveer, Lynda Jm Juffermans, Niels van Royen, Yolande Appelman, Thomas R Porter, Otto Kamp
In the past few decades, cardiac ultrasound has become a widely available, easy-to-use diagnostic tool in many scenarios in acute cardiac care. The introduction of microbubbles extended its diagnostic value. Not long thereafter, several investigators explored the therapeutic potential of contrast ultrasound on thrombus dissolution. Despite large improvements in therapeutic options, acute ST elevation myocardial infarction remains one of the main causes of mortality and morbidity in the western world. The therapeutic effect of contrast ultrasound on thrombus dissolution might prove to be a new, effective treatment strategy in this group of patients...
September 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28862032/heparin-pre-treatment-in-patients-with-st-segment-elevation-myocardial-infarction-and-the-risk-of-intracoronary-thrombus-and-total-vessel-occlusion-insights-from-the-taste-trial
#10
Sofia Karlsson, Pontus Andell, Moman A Mohammad, Sasha Koul, Göran K Olivecrona, Stefan K James, Ole Fröbert, David Erlinge
BACKGROUND: Pre-treatment with unfractionated heparin is common in ST-segment elevation myocardial infarction (STEMI) protocols, but the effect on intracoronary thrombus burden is unknown. We studied the effect of heparin pre-treatment on intracoronary thrombus burden and Thrombolysis in Myocardial Infarction (TIMI) flow prior to percutaneous coronary intervention in patients with STEMI. METHODS: The Thrombus Aspiration in ST-Elevation Myocardial Infarction in Scandinavia (TASTE) trial angiographically assessed intracoronary thrombus burden and TIMI flow, prior to percutaneous coronary intervention, in patients with STEMI...
August 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28849947/what-do-small-serum-creatinine-changes-tell-us-about-outcomes-after-acute-myocardial-infarction
#11
Johann Auer, Frederik H Verbrugge, Gudrun Lamm
Acute kidney injury (AKI), mostly defined as a rise in serum creatinine concentration of more than 0.5 mg/dl, is a common, serious, and potentially preventable complication of percutaneous coronary intervention and is associated with adverse outcomes including an increased risk of inhospital mortality. Recent data from the National Cardiovascular Data Registry/Cath-PCI registry including 985,737 consecutive patients undergoing percutaneous coronary intervention suggest that approximately 7% experienced AKI with a reported incidence of 3-19%...
August 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28849946/intravenous-vernakalant-in-comparison-with-intravenous-flecainide-in-the-cardioversion-of-recent-onset-atrial-fibrillation
#12
Hanna Pohjantähti-Maaroos, Harri Hyppölä, Maria Lekkala, Emma Sinisalo, Antti Heikkola, Juha Hartikainen
BACKGROUND: Pharmacological cardioversion of atrial fibrillation is a reasonable alternative for electrical cardioversion in acute atrial fibrillation. We compared the efficacy and safety of intravenous vernakalant and intravenous flecainide in patients with recent-onset (< 48 h) atrial fibrillation. METHODS: A total of 200 consecutive patients, 100 patients undergoing cardioversion with intravenous vernakalant and 100 patients undergoing cardioversion with intravenous flecainide, were included in this single centre non-randomized retrospective study...
August 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28841028/clinical-impact-and-predictors-of-complete-st-segment-resolution-after-primary-percutaneous-coronary-intervention-a-subanalysis-of-the-atlantic-trial
#13
Enrico Fabris, Arnoud van 't Hof, Christian W Hamm, Frédéric Lapostolle, Jens F Lassen, Shaun G Goodman, Jurriën M Ten Berg, Leonardo Bolognese, Angel Cequier, Mohamed Chettibi, Christopher J Hammett, Kurt Huber, Magnus Janzon, Béla Merkely, Robert F Storey, Uwe Zeymer, Warren J Cantor, Anne Tsatsaris, Mathieu Kerneis, Abdourahmane Diallo, Eric Vicaut, Gilles Montalescot
BACKGROUND: In the ATLANTIC (Administration of Ticagrelor in the catheterization laboratory or in the Ambulance for New ST elevation myocardial Infarction to open the Coronary artery) trial the early use of aspirin, anticoagulation, and ticagrelor coupled with very short medical contact-to-balloon times represent good indicators of optimal treatment of ST-elevation myocardial infarction and an ideal setting to explore which factors may influence coronary reperfusion beyond a well-established pre-hospital system...
August 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28828881/correlates-and-prognostic-impact-of-new-onset-heart-failure-after-st-segment-elevation-myocardial-infarction-treated-with-primary-percutaneous-coronary-intervention-insights-from-the-infuse-ami-trial
#14
Gennaro Giustino, Björn Redfors, Sorin J Brener, Ajay J Kirtane, Philippe Généreux, Akiko Maehara, Dariusz Dudek, Thomas Neunteufl, D Christopher Metzger, Aaron Crowley, Roxana Mehran, C Michael Gibson, Gregg W Stone
BACKGROUND: The determinants and significance of early (30-day) heart failure symptoms after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction (STEMI) remain unclear. We investigated the clinical and imaging correlates of early post-discharge heart failure in patients with STEMI, and evaluated its impact on clinical outcomes. METHODS: Patients from the INFUSE-AMI trial were categorized according to New York Heart Association (NYHA) functional classification at their 30-day visit (NYHA class ≥2 versus 1)...
August 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28816063/acute-cardiovascular-care-association-position-paper-on-intensive-cardiovascular-care-units-an-update-on-their-definition-structure-organisation-and-function
#15
Eric Bonnefoy-Cudraz, Hector Bueno, Gianni Casella, Elia De Maria, Donna Fitzsimons, Sigrun Halvorsen, Christian Hassager, Zaza Iakobishvili, Ahmed Magdy, Toomas Marandi, Jorge Mimoso, Alexander Parkhomenko, Susana Price, Richard Rokyta, Francois Roubille, Pranas Serpytis, Avi Shimony, Janina Stepinska, Diana Tint, Elina Trendafilova, Marco Tubaro, Christiaan Vrints, David Walker, Doron Zahger, Endre Zima, Robert Zukermann, Maddalena Lettino
Acute cardiovascular care has progressed considerably since the last position paper was published 10 years ago. It is now a well-defined, complex field with demanding multidisciplinary teamworking. The Acute Cardiovascular Care Association has provided this update of the 2005 position paper on acute cardiovascular care organisation, using a multinational working group. The patient population has changed, and intensive cardiovascular care units now manage a large range of conditions from those simply requiring specialised monitoring, to critical cardiovascular diseases with associated multi-organ failure...
August 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28777005/predicting-two-year-mortality-from-discharge-after-acute-coronary-syndrome-an-internationally-based-risk-score
#16
Stuart J Pocock, Yong Huo, Frans Van de Werf, Simon Newsome, Chee Tang Chin, Ana Maria Vega, Jesús Medina, Héctor Bueno
BACKGROUND: Long-term risk of post-discharge mortality associated with acute coronary syndrome remains a concern. The development of a model to reliably estimate two-year mortality risk from hospital discharge post-acute coronary syndrome will help guide treatment strategies. METHODS: EPICOR (long-tErm follow uP of antithrombotic management patterns In acute CORonary syndrome patients, NCT01171404) and EPICOR Asia (EPICOR Asia, NCT01361386) are prospective observational studies of 23,489 patients hospitalized for an acute coronary syndrome event, who survived to discharge and were then followed up for two years...
August 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29039990/update-on-st-elevation-myocardial-infarction
#17
Christiaan Jm Vrints
No abstract text is available yet for this article.
October 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/27821790/patient-delay-in-patients-with-st-elevation-myocardial-infarction-time-patterns-and-predictors-for-a-prolonged-delay
#18
Christel Ga Nielsen, Kristina G Laut, Lisette O Jensen, Jan Ravkilde, Christian J Terkelsen, Steen D Kristensen
BACKGROUND AND AIMS: To improve treatment success of ST-elevation myocardial infarction, a minimal delay from symptom onset to reperfusion therapy is crucial. The patient's response to initial symptoms (patient delay) substantially affects the delay. We investigated time patterns of patient delay during a seven-year time period, and aimed to identify key predictors that affect the length of the patient delay. METHODS: Data on 5848 patients hospitalized with ST-elevation myocardial infarction and treated with primary percutaneous intervention during the period 2003-2009 were obtained from Danish registry databases...
October 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/27655918/editor-s-choice-impact-of-immediate-multivessel-percutaneous-coronary-intervention-versus-culprit-lesion-intervention-on-1-year-outcome-in-patients-with-acute-myocardial-infarction-complicated-by-cardiogenic-shock-results-of-the-randomised-iabp-shock-ii-trial
#19
Uwe Zeymer, Karl Werdan, Gerhard Schuler, Ralf Zahn, Franz-Josef Neumann, Georg Fürnau, Suzanne de Waha, Steffen Schneider, Holger Thiele
BACKGROUND: Current guidelines recommend immediate multivessel percutaneous coronary intervention (PCI) in patients with cardiogenic shock, despite the lack of randomised trials. We sought to investigate the use and impact on outcome of multivessel PCI in comparison to culprit lesion only PCI in a retrospective analysis in patients with cardiogenic shock complicating acute myocardial infarction. METHODS AND RESULTS: In the randomised IABP-SHOCK II trial, investigating the effect of intra-aortic balloon pump on outcome, 451 (75%) of the total of 600 patients had multivessel coronary artery disease and underwent PCI...
October 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/27485141/editor-s-choice-sex-differences-in-young-patients-with-acute-myocardial-infarction-a-virgo-study-analysis
#20
Emily M Bucholz, Kelly M Strait, Rachel P Dreyer, Stacy T Lindau, Gail D'Onofrio, Mary Geda, Erica S Spatz, John F Beltrame, Judith H Lichtman, Nancy P Lorenze, Hector Bueno, Harlan M Krumholz
AIMS: Young women with acute myocardial infarction (AMI) have a higher risk of adverse outcomes than men. However, it is unclear how young women with AMI are different from young men across a spectrum of characteristics. We sought to compare young women and men at the time of AMI on six domains of demographic and clinical factors in order to determine whether they have distinct profiles. METHODS AND RESULTS: Using data from Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients (VIRGO), a prospective cohort study of women and men aged ⩽55 years hospitalized for AMI ( n = 3501) in the United States and Spain, we evaluated sex differences in demographics, healthcare access, cardiovascular risk and psychosocial factors, symptoms and pre-hospital delay, clinical presentation, and hospital management for AMI...
October 2017: European Heart Journal. Acute Cardiovascular Care
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