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European Heart Journal. Acute Cardiovascular Care

Edward Koifman, Roy Beigel, Zaza Iakobishvili, Nir Shlomo, Yitschak Biton, Avi Sabbag, Elad Asher, Shaul Atar, Shmuel Gottlieb, Ronny Alcalai, Doron Zahger, Amit Segev, Ilan Goldenberg, Rafael Strugo, Shlomi Matetzky
BACKGROUND: Ischemic time has prognostic importance in ST-elevation myocardial infarction patients. Mobile intensive care unit use can reduce components of total ischemic time by appropriate triage of ST-elevation myocardial infarction patients. METHODS: Data from the Acute Coronary Survey in Israel registry 2000-2010 were analyzed to evaluate factors associated with mobile intensive care unit use and its impact on total ischemic time and patient outcomes. RESULTS: The study comprised 5474 ST-elevation myocardial infarction patients enrolled in the Acute Coronary Survey in Israel registry, of whom 46% ( n=2538) arrived via mobile intensive care units...
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
Maycel Ishak, Danish Ali, Marion J Fokkert, Robbert J Slingerland, Rudolf T Tolsma, Erik Badings, Aize van der Sluis, Fred van Eenennaam, Arend Mosterd, Jurriën M Ten Berg, Arnoud Wj van 't Hof
BACKGROUND: The first study of the FamouS Triage project investigates the feasibility of ruling out a myocardial infarction in pre-hospital chest pain patients without electrocardiographic ST-segment elevation by using the modified HEART score at the patient's home, incorporating only a single highly sensitive troponin T measurement. METHODS: A venous blood sample was drawn in the ambulance from 1127 consecutive chest pain patients for measurement of the pre-hospital highly sensitive troponin T levels, in order to establish a pre-hospital HEART score (i...
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
Julien Magne, Baptiste Salerno, Dania Mohty, Claire Serena, Florence Rolle, Alessandro Piccardo, Najmeddine Echahidi, Alexandre Le Guyader, Victor Aboyans
OBJECTIVE: Postoperative atrial fibrillation is a major complication following coronary artery bypass graft. We hypothesized that, beyond clinical and electrocardiogram (ECG) data, transthoracic echocardiography could improve the prediction of postoperative atrial fibrillation. METHODS: We prospectively studied 169 patients in sinus rhythm who underwent isolated coronary artery bypass graft in our institution. Clinical, biological, ECG and transthoracic echocardiography data were collected within 24 h before surgery...
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
Benedikt Schrage, Hanno Grahn, Florian M Wagner, Alexander Bernhardt, Meike Rybczynski, Stefan Blankenberg, Hermann Reichenspurner, Markus J Barten
BACKGROUND: Pump thrombosis is a major complication of the continuous flow left ventricular assist device. Pump exchange is seen as the therapeutic gold standard. In this study, we report on our experience with using tissue-type plasminogen activator thrombolysis for therapy of pump thrombosis. METHODS: We report on our experience with treatment of continuous flow left ventricular assist device pump thrombosis with the HVAD using tissue-type plasminogen activator thrombolysis in nine patients with 16 thrombotic events...
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
Michał Mazurek, Gregory Yh Lip
No abstract text is available yet for this article.
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
Matilde Winther-Jensen, Jesper Kjaergaard, Jens F Lassen, Lars Køber, Christian Torp-Pedersen, Steen M Hansen, Freddy Lippert, Kristian Kragholm, Erika F Christensen, Christian Hassager
AIM: The purpose of this study was to describe the implantation of implantable cardioverter defibrillator after out-of-hospital cardiac arrest caused by myocardial infarction in Denmark 2001-2012 and subsequent survival. METHODS: The Danish Cardiac Arrest Registry was used to identify patients ⩾18 years surviving to discharge without prior implantable cardioverter defibrillator. Information on cardioverter defibrillator implantation was obtained from the National Patient Registry...
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
Trygve Husebye, Jan Eritsland, Reidar Bjørnerheim, Geir Ø Andersen
BACKGROUND: Echocardiography is recommended for assessment of left ventricular systolic function in patients with acute heart failure but few randomised trials have validated techniques like tissue Doppler (TDI) and speckle tracking (STE) in patients with acute heart failure following ST-elevation myocardial infarction. METHODS: This was a substudy from the LEAF (LEvosimendan in Acute heart Failure following myocardial infarction) trial (NCT00324766 ), which randomised 61 patients developing acute heart failure, including cardiogenic shock, within 48 hours after ST-elevation myocardial infarction, double-blind to a 25-hour infusion of levosimendan or placebo...
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
Raphael Wurm, Anna Cho, Henrike Arfsten, Raphael van Tulder, Christian Wallmüller, Philipp Steininger, Fritz Sterz, Kristina Tendl, Csilla Balassy, Klaus Distelmaier, Martin Hülsmann, Gottfried Heinz, Christopher Adlbrecht
BACKGROUND AND AIM OF THE STUDY: Non-occlusive mesenteric ischaemia (NOMI) is characterised by hypoperfusion of the intestines without evidence of mechanical obstruction, potentially leading to extensive ischaemia and necrosis. Low cardiac output appears to be a major risk factor. Cardiopulmonary resuscitation aims at restoring blood flow after cardiac arrest. However, post restoration of spontaneous circulation, myocardial stunning limits immediate recovery of sufficient cardiac function...
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
Juan J Russo, Tyler E James, Benjamin Hibbert, F Daniel Ramirez, Trevor Simard, Christina Osborne, Jordan Bernick, George A Wells, Michel R Le May
BACKGROUND: The optimal blood glucose target during the early hospitalisation of comatose survivors of out-of-hospital cardiac arrest (OHCA) has not been established. METHODS: In a retrospective cohort study, we examined clinical outcomes in relation to mean blood glucose during the first 96 hours of hospital admission in comatose survivors of OHCA with an initial shockable rhythm. Mean blood glucose was assessed as a continuous (primary analysis) and categorical variable: <6 mmol/L, 6 to <8 mmol/L and ⩾8 mmol/L...
December 1, 2016: European Heart Journal. Acute Cardiovascular Care
Roland Klingenberg, Soheila Aghlmandi, Lorenz Räber, Baris Gencer, David Nanchen, Dik Heg, Sebastian Carballo, Nicolas Rodondi, François Mach, Stephan Windecker, Peter Jüni, Arnold von Eckardstein, Christian M Matter, Thomas F Lüscher
BACKGROUND: Clinical scores and biomarkers improve risk stratification of patients with acute coronary syndromes. However, little is known about their value in patients referred for coronary angiography. METHODS: Consecutive patients admitted at four Swiss university hospitals with a diagnosis of acute coronary syndrome were enrolled into the SPUM-ACS Biomarker Cohort between 2009 and 2012. Patients were followed at 30 days and 1 year with assessment of adjudicated events including all-cause mortality and the composite of all-cause mortality or non-fatal recurrent myocardial infarction...
December 1, 2016: European Heart Journal. Acute Cardiovascular Care
Arturo Evangelista, José Manuel Rabasa, Victor X Mosquera, Antonio Barros, Ruben Fernández-Tarrio, Francisco Calvo-Iglesias, Carlos Ferrera, Jose Rozado, Jordi López-Ayerbe, Carmen Garrote, Jose-Alberto Sanroman, Francisco Nistal, Violeta Sanchez, Jose-Antonio García Robles, Francisco Valera, Carlos Ballester, Oscar Gil-Albarova, Francisco Domínguez, Ricardo Vivancos, Alicia Mateo-Martinez, Pastora Gallego, Mercedes González-Molina, Covadonga Fernández-Golfin, Miguel Josa, Aquilino Hurlé, Ibon Rodríguez-Sanchez, Jose Rodríguez-Palomares
BACKGROUND: Recent advances in the diagnosis and treatment of acute aortic syndrome should improve the outcome of this disease. The Spanish Registry of Acute Aortic Syndrome aimed to assess current results in acute aortic syndrome management in a wide cohort of hospitals in the same geographical area. METHODS: From January 2012 to January 2014, 26 tertiary hospitals included 629 consecutive patients with acute aortic syndrome: 73% men, mean age 64.7±14 years (range 22-92), 443 type A (70...
December 1, 2016: European Heart Journal. Acute Cardiovascular Care
Maximilian Tscharre, Christina Hauser, Miklos Rohla, Matthias K Freynhofer, Johann Wojta, Kurt Huber, Thomas W Weiss
AIMS: We investigated the association between epicardial adipose tissue (EAT) thickness and cardiovascular outcomes in a cohort of high-risk patients with acute coronary syndrome undergoing percutaneous coronary intervention. METHODS: Of 1198 patients undergoing percutaneous coronary intervention, transthoracic echocardiography was performed in 438 patients during the index hospitalization. EAT thickness was measured in the parasternal long-axis view perpendicularly on the free wall of the right ventricle at end-systole in three consecutive cardiac cycles and then averaged...
November 18, 2016: European Heart Journal. Acute Cardiovascular Care
François Schiele, Michel Farnier, Michel Krempf, Eric Bruckert, Jean Ferrières
In patients admitted for acute coronary syndrome (ACS), the guidelines of the European Society of Cardiology give a Class I, Level A recommendation for the prescription of high-intensity statins to be initiated as early as possible, regardless of the low-density lipoprotein cholesterol (LDL-C) level. Although statins are widely prescribed after ACS, the intensity of therapy and the proportion of patients achieving target LDL-C values are often not in line with recommendations due to a lack of compliance with guidelines by the physicians, a lack of compliance with treatment or poor tolerance by patients, and poor dose adaptation...
November 17, 2016: European Heart Journal. Acute Cardiovascular Care
Akram Y Elgendy, Islam Y Elgendy, Hend Mansoor, Ahmed N Mahmoud
BACKGROUND: Evidence remains inconsistent regarding the incidence and prognosis of Takotsubo syndrome in the setting of subarachnoid hemorrhage. Thus, we aimed to evaluate the clinical presentation and in-hospital mortality of these patients. METHODS: A systematic review of the electronic databases was conducted for studies involving patients with spontaneous subarachnoid hemorrhage and concomitant findings of classical Takotsubo syndrome on transthoracic echocardiogram...
November 16, 2016: European Heart Journal. Acute Cardiovascular Care
Christel Ga Nielsen, Kristina G Laut, Lisette O Jensen, Jan Ravkilde, Christian J Terkelsen, Steen D Kristensen
BACKGROUND AND AIMS: To improve treatment success of ST-elevation myocardial infarction, a minimal delay from symptom onset to reperfusion therapy is crucial. The patient's response to initial symptoms (patient delay) substantially affects the delay. We investigated time patterns of patient delay during a seven-year time period, and aimed to identify key predictors that affect the length of the patient delay. METHODS: Data on 5848 patients hospitalized with ST-elevation myocardial infarction and treated with primary percutaneous intervention during the period 2003-2009 were obtained from Danish registry databases...
November 7, 2016: European Heart Journal. Acute Cardiovascular Care
Nadia Bouabdallaoui, Guillaume Lebreton, Pierre Demondion, Ahmed Charfeddine, Pascal Leprince
BACKGROUND: Left ventricular assist devices are valuable options for mechanical circulatory support in patients with severe heart failure as a bridge to cardiac transplantation, to recovery, or as destination therapy. Transoesophageal echocardiography plays a key role in the management of left ventricular assist device patients; either in guiding the device implantation or in post-operative haemodynamic assessment. The aim of this observational study is to investigate the usefulness of a miniaturized transoesophageal echocardiography probe designed for continuous haemodynamic monitoring (haemodynamic transoesophageal echocardiography; ImaCor, Garden City, NY) in the haemodynamic assessment of patients undergoing left ventricular assist device implantation...
December 2016: European Heart Journal. Acute Cardiovascular Care
Philipp Bahrmann, Michael Christ, Benjamin Hofner, Anke Bahrmann, Stefan Achenbach, Cornel Christian Sieber, Thomas Bertsch
BACKGROUND: Risk stratification of elderly patients presenting with heart failure (HF) to an emergency department (ED) is an unmet challenge. We prospectively investigated the prognostic performance of different biomarkers in unselected older patients in the ED. METHODS: We consecutively enrolled 302 non-surgical patients ⩾70 years presenting to the ED with a wide range of cardiovascular and non-cardiovascular comorbid conditions. N-terminal pro-B-type natriuretic peptide (NT-proBNP), mid-regional pro-adrenomedullin (MR-proADM), mid-regional pro-atrial natriuretic peptide (MR-proANP), C-terminal pro-endothelin-1 (CT-proET-1), ultrasensitive C-terminal pro-arginine-vasopressin (Copeptin-us) and high-sensitivity cardiac troponin T (hs-cTnT) were measured at admission...
December 2016: European Heart Journal. Acute Cardiovascular Care
Hans-Josef Feistritzer, Sebastian J Reinstadler, Gert Klug, Christian Kremser, Andrea Rederlechner, Johannes Mair, Silvana Müller, Wolfgang-Michael Franz, Bernhard Metzler
BACKGROUND: Aortic stiffness is associated with increased left ventricular (LV) afterload, a process which is accompanied by a release of natriuretic peptides. Aortic pulse wave velocity (PWV) has been demonstrated to be the functional surrogate of aortic stiffness. We sought to investigate the impact of aortic PWV on N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations in patients with acute myocardial infarction (AMI). METHODS: This prospective observational study included 86 consecutive patients undergoing percutaneous coronary intervention for AMI...
December 2016: European Heart Journal. Acute Cardiovascular Care
Rasmus Rørth, Emil L Fosbøl, Ulrik M Mogensen, Kasper Iversen, Martin Iversen, Henning Kelbæk, Frants Pedersen, Thomas Engstrøm, Christian Torp-Pedersen, Gunnar Gislason, Lars Køber
PURPOSE: β2-Agonists are widely used for relief of respiratory symptoms. Studies so far have reported conflicting results regarding use of β2-agonists and risk of myocardial infarction (MI). Yet, coronary angiographical data and longitudinal outcomes data are sparse and could help explain if there is an association between use of β2-agonists and MI. METHODS: Using a novel data-linkage of the Eastern Danish Heart Registry and nationwide administrative registries we identified a cohort of patients referred for acute coronary angiography due to ST-elevation MI (STEMI)...
December 2016: European Heart Journal. Acute Cardiovascular Care
Hesham R Omar
INTRODUCTION: Electrocardiographic (ECG) abnormalities are seen in 70%-80% of patients with acute pulmonary embolism (APE). Rarely, APE presents with ST-segment elevation (STE) in leads V1-V4, mimicking ST-segment elevation myocardial infarction (STEMI). Herein, we describe a case of APE presenting with STE in V1-V3, along with a comprehensive review of the literature. METHODS: We reviewed Pubmed/Medline indexed articles from 1950 to 2014 reporting cases of APE presenting with STE in V1-V3 or V4 (V1-V3/V4)...
December 2016: European Heart Journal. Acute Cardiovascular Care
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