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European Heart Journal. Acute Cardiovascular Care

Paul M Haller, Kris G Vargas, Maria C Haller, Edita Piackova, Johann Wojta, Mariann Gyöngyösi, Bernard J Gersh, Attila Kiss, Bruno K Podesser, Kurt Huber
BACKGROUND: The efficacy of remote ischaemic conditioning in clinical trials of ST-segment elevation myocardial infarction (STEMI) or elective percutaneous coronary intervention is controversial. We aimed to systematically review and meta-analyse whether remote ischaemic conditioning reduces myocardial damage in those patients. METHODS: We searched PubMed, Embase and Web of Science from inception until December 2017 for randomised clinical trials evaluating remote ischaemic conditioning versus a control group...
June 1, 2018: European Heart Journal. Acute Cardiovascular Care
Carlos L Alviar, Alejandra Gutierrez, Leslie Cho, Amar Krishnaswamy, Amr Saleh, Michael A Lincoff, Eric Roselli, Michael Militello, Venu Menon
BACKGROUND: Sodium nitroprusside is the preferred agent for the treatment of high blood pressure during acute aortic syndrome if blood pressure remains elevated after heart rate control with beta-blockers. The increasing cost of sodium nitroprusside in the USA led us to assess the efficacy and safety of intravenous clevidipine, a calcium channel blocker with quick onset of action, short half-life and significantly lower costs than sodium nitroprusside, in patients presenting with acute aortic syndrome...
June 1, 2018: European Heart Journal. Acute Cardiovascular Care
Baris Gencer, Fabio Rigamonti, David Nanchen, Roland Klingenberg, Lorenz Räber, Elisavet Moutzouri, Reto Auer, David Carballo, Dik Heg, Stephan Windecker, Thomas Felix Lüscher, Christian M Matter, Nicolas Rodondi, François Mach, Marco Roffi
BACKGROUND: Controversy remains regarding the prevalence of hyperglycaemia in non-diabetic patients hospitalised with acute coronary syndrome and its prognostic value for long-term outcomes. METHODS AND RESULTS: We evaluated the prevalence of hyperglycaemia (defined as fasting glycaemia ⩾10 mmol/l) among patients with no known diabetes at the time of enrolment in the prospective Special Program University Medicine-Acute Coronary Syndromes cohort, as well as its impact on all-cause death, myocardial infarction, stroke and incidence of diabetes at one year...
June 1, 2018: European Heart Journal. Acute Cardiovascular Care
Patrick Sulzgruber, Sebastian Schnaubelt, Lorenz Koller, Georg Goliasch, Jan Niederdöckl, Alexander Simon, Feras El-Hamid, David-Jonas Rothgerber, Johann Wojta, Alexander Niessner
BACKGROUND: The development of cardiac arrhythmias resulting in cardiac arrest represents a severe complication in patients with acute myocardial infarction. While the worsening of the prognosis in this vulnerable patient collective is well known, less attention has been paid to its age-specific relevance from a long-term perspective. METHODS: Based on a clinical acute myocardial infarction registry we analysed 832 patients with acute myocardial infarction within the current analysis...
June 1, 2018: European Heart Journal. Acute Cardiovascular Care
Jan-Thorben Sieweke, Tobias Jonathan Pfeffer, Dominik Berliner, Tobias König, Maximiliane Hallbaum, L Christian Napp, Jörn Tongers, Christian Kühn, Jan D Schmitto, Denise Hilfiker-Kleiner, Andreas Schäfer, Johann Bauersachs
INTRODUCTION: Acute peripartum cardiomyopathy complicated by cardiogenic shock is a rare but life-threatening disease. A prolactin fragment is considered causal for the pathogenesis of peripartum cardiomyopathy. This analysis sought to investigate the role of early percutaneous mechanical circulatory support with micro-axial flow-pumps and/or veno-arterial extracorporeal membrane oxygenation in combination with the prolactin inhibitor bromocriptine in refractory cardiogenic shock complicating peripartum cardiomyopathy...
May 1, 2018: European Heart Journal. Acute Cardiovascular Care
Jamie R Privratsky, Sebastian Diaz, Alina Nicoara, Mani A Daneshmand
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is an increasingly utilized life-saving measure. However, left-ventricular distention from inadequate left-ventricular off-loading can lead to unwanted pulmonary and cardiac complications. We are writing to indicate our agreement with a recent article by Brechot et al. published in the June 2017 issue where the authors demonstrated that intra-aortic balloon pump provides mechanical support to off-load the left ventricle during VA-ECMO, which prevents pulmonary edema...
May 1, 2018: European Heart Journal. Acute Cardiovascular Care
Kenji Sadamatsu, Susumu Takase, Shuichiro Sagara, Kensuke Ohe, Jun-Ichiro Nishi, Hideki Tashiro, Tomokazu Kosuga, Hiroshi Yasunaga
BACKGROUND: The feasibility of medical management for select patients with acute type A aortic dissection has been reported from a few institutions. In this study, we retrospectively investigated the safety and feasibility of our conservative approach for patients with type A aortic dissection in daily practice. METHODS: From January 2013 to December 2017, 131 consecutive patients were admitted to our institution for acute aortic dissection, including 58 patients of type A...
May 1, 2018: European Heart Journal. Acute Cardiovascular Care
Neil Beri, Lori B Daniels, Allan Jaffe, Christian Mueller, Inder Anand, W Frank Peacock, Judd E Hollander, Christopher DeFilippi, Donald Schreiber, James McCord, Alexander T Limkakeng, Alan H B Wu, Fred S Apple, Deborah B Diercks, John T Nagurney, Richard M Nowak, Chad M Cannon, Paul Clopton, Sean-Xavier Neath, Robert H Christenson, Christopher Hogan, Gary Vilke, Alan Maisel
BACKGROUND: Copeptin in combination with troponin has been shown to have incremental value for the early rule-out of myocardial infarction, but its performance in Black patients specifically has never been examined. In light of a potential for wider use, data on copeptin in different relevant cohorts are needed. This is the first study to determine whether copeptin is equally effective at ruling out myocardial infarction in Black and Caucasian races. METHODS: This analysis of the CHOPIN trial included 792 Black and 1075 Caucasian patients who presented to the emergency department with chest pain and had troponin-I and copeptin levels drawn...
May 1, 2018: European Heart Journal. Acute Cardiovascular Care
Nariman Sepehrvand, Wendimagegn Alemayehu, Padma Kaul, Rick Pelletier, Aminu K Bello, Robert C Welsh, Paul W Armstrong, Justin A Ezekowitz
BACKGROUND: Despite guideline recommendations, the majority of patients with symptoms suggestive of acute coronary syndrome do not use emergency medical services to reach the emergency department (ED). The aim of this study was to investigate the factors associated with EMS utilisation and subsequent patient outcomes. METHODS: Using administrative data, all patients who presented to an ED in the metropolitan areas of Edmonton and Calgary in the years of 2007-2013 with main ED diagnosis of acute coronary syndrome, stable angina or chest pain were included...
April 1, 2018: European Heart Journal. Acute Cardiovascular Care
(no author information available yet)
No abstract text is available yet for this article.
April 1, 2018: European Heart Journal. Acute Cardiovascular Care
Martin Reindl, Hans-Josef Feistritzer, Sebastian Johannes Reinstadler, Lukas Mueller, Christina Tiller, Christoph Brenner, Agnes Mayr, Benjamin Henninger, Johannes Mair, Gert Klug, Bernhard Metzler
BACKGROUND: Adverse left ventricular remodeling is one of the major determinants of heart failure and mortality in patients surviving ST-segment elevation myocardial infarction (STEMI). The hypothalamic-pituitary-thyroid axis is a key cardiovascular regulator; however, the relationship between hypothalamic-pituitary-thyroid status and post-STEMI left ventricular remodeling is unclear. We aimed to investigate the association between thyroid-stimulating hormone concentrations and the development of left ventricular remodeling following reperfused STEMI...
April 1, 2018: European Heart Journal. Acute Cardiovascular Care
Julien Magne, Claire Serena, Baptiste Salerno, Dania Mohty, Jean-Philippe Marsaud, Jean-David Blossier, Alessandro Piccardo, Elisabeth Cornu, Alexandre Le Guyader, Victor Aboyans
OBJECTIVE: To assess the performance of transthoracic echocardiographic parameters to predict operative mortality and morbidity in patients undergoing coronary artery bypass grafting, and to assess its incremental prognostic value as compared to the Society of Thoracic Surgeons (STS) score. MATERIALS AND METHODS: We prospectively collected the clinical and biological data required to calculate the STS score in patients hospitalised for coronary artery bypass grafting...
April 1, 2018: European Heart Journal. Acute Cardiovascular Care
Max Lenz, Konstantin A Krychtiuk, Georg Goliasch, Klaus Distelmaier, Johann Wojta, Gottfried Heinz, Walter S Speidl
BACKGROUND: Patients treated at medical intensive care units suffer from various pathologies and often present with elevated troponin T (TnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels. Both markers may reflect different forms of cardiac involvement in critical illness. Therefore, the aim of our study was to examine the synergistic prognostic potential of NT-proBNP and high-sensitivity TnT (hs)TnT in unselected critically ill patients. METHODS: We included all consecutive patients admitted to our intensive care unit within one year, excluding those suffering from acute myocardial infarction or undergoing cardiac surgery and measured NT-proBNP and TnT plasma levels on the day of admission and 72 hours thereafter...
April 1, 2018: European Heart Journal. Acute Cardiovascular Care
Ilia Litovchik, David Pereg, Nir Shlomo, Dina Vorobeichik, Roy Beigel, Zaza Iakobishvili, Zvi Vered, Ilan Goldenberg, Sa'ar Minha
BACKGROUND: Readmissions following acute myocardial infarction are associated with poor outcomes and a heavy economic burden. There are few evidence-based data on the characteristics and outcomes of patients readmitted following acute coronary syndrome. We explored the incidence and outcomes of patients readmitted after an acute coronary syndrome in the past decade. METHODS: The study population comprised all acute coronary syndrome patients who were enrolled and prospectively followed up in the biennial Acute Coronary Syndrome Israeli Survey from 2000 to 2013...
April 1, 2018: European Heart Journal. Acute Cardiovascular Care
Thomas Lindow, Olle Pahlm, Charles W Olson, Ardavan Khoshnood, Ulf Ekelund, Marcus Carlsson, Cees A Swenne, Sumche Man, Henrik Engblom
Electrocardiographic Decision Support - Myocardial Ischaemia (EDS-MI) is a graphical decision support for detection and localization of acute transmural ischaemia. A recent study indicated that EDS-MI performs well for detection of acute transmural ischaemia. However, its performance has not been tested in patients with non-ischaemic ST-deviation. We aimed to optimize the diagnostic accuracy of EDS-MI in patients with verified acute coronary occlusion as well as patients with non-ischaemic ST deviation and compare its performance with STEMI criteria...
April 1, 2018: European Heart Journal. Acute Cardiovascular Care
Uwe Zeymer, Lieven Annemans, Nicolas Danchin, Stuart Pocock, Simon Newsome, Frans Van de Werf, Jesús Medina, Héctor Bueno
BACKGROUND: Atrial fibrillation (AF) is associated with increased morbidity in acute coronary syndrome patients, but impact on outcomes beyond 1 year is unclear. METHODS: This was a post-hoc analysis from the long-tErm follow-uP of antithrombotic management patterns In acute CORonary syndrome patients (EPICOR) registry (NCT01171404), a prospective, observational study conducted in Europe and Latin America, which enrolled acute coronary syndrome survivors at discharge...
April 1, 2018: European Heart Journal. Acute Cardiovascular Care
Christiaan Jm Vrints
No abstract text is available yet for this article.
June 2018: European Heart Journal. Acute Cardiovascular Care
Frederik H Verbrugge
Diuretic resistance is a powerful predictor of adverse outcome in acute heart failure (AHF), irrespectively of underlying glomerular filtration rate. Metrics of diuretic efficacy such as natriuresis, urine output, weight loss, net fluid balance, or fractional sodium excretion, differ in their risk for measurement error, convenience, and biological plausibility, which should be taken into account when interpreting their results. Loop diuretic resistance in AHF has multiple causes including altered drug pharmacokinetics, impaired renal perfusion and effective circulatory volume, neurohumoral activation, post-diuretic sodium retention, the braking phenomenon and functional as well as structural adaptations in the nephron...
June 2018: European Heart Journal. Acute Cardiovascular Care
Christiaan J M Vrints
No abstract text is available yet for this article.
April 2018: European Heart Journal. Acute Cardiovascular Care
Sergio Leonardi, Hector Bueno, Ingo Ahrens, Christian Hassager, Eric Bonnefoy, Maddalena Lettino
No abstract text is available yet for this article.
April 2018: European Heart Journal. Acute Cardiovascular Care
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