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European Heart Journal. Acute Cardiovascular Care

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https://www.readbyqxmd.com/read/29451402/frailty-and-the-management-of-patients-with-acute-cardiovascular-disease-a-position-paper-from-the-acute-cardiovascular-care-association
#1
D M Walker, C P Gale, G Lip, F J Martin-Sanchez, H F McIntyre, C Mueller, S Price, J Sanchis, M T Vidan, C Wilkinson, U Zeymer, H Bueno
Frailty is increasingly seen among patients with acute cardiovascular disease. A combination of an ageing population, improved disease survival, treatable long-term conditions as well as a greater recognition of the syndrome has accelerated the prevalence of frailty in the modern world. Yet, this has not been matched by an expansion of research. National and international bodies have identified acute cardiovascular disease in the frail as a priority area for care and an entity that requires careful clinical decisions, but there remains a paucity of guidance on treatment efficacy and safety, and how to manage this complex group...
February 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29417828/early-heart-attack-care-as-a-prehospital-programme-designed-to-supplement-the-established-chest-pain-unit-concept-in-germany
#2
Frank Breuckmann, Tienush Rassaf
No abstract text is available yet for this article.
February 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29405734/mortality-in-patients-with-cardiogenic-shock-treated-with-the-impella-cp-microaxial-pump-for-isolated-left-ventricular-failure
#3
Jan-Thorben Sieweke, Dominik Berliner, Jörn Tongers, L Christian Napp, Ulrike Flierl, Florian Zauner, Johann Bauersachs, Andreas Schäfer
AIMS: Cardiogenic shock is still associated with high mortality rates of around 50%. Intra-aortic counterpulsation had been frequently used in cardiogenic shock, but was previously found to provide no mortality benefit. We investigated the effect of an interdisciplinary and multiprofessional routine strategy of early invasive haemodynamic support in combination with complete revascularization in patients with cardiogenic shock before admission to our intensive care unit. METHODS AND RESULTS: We analysed all cardiogenic shock patients (mean age 62±13 years) presenting at our institution between 2013 and mid 2016, who received an Impella CP microaxial pump for isolated left ventricle support ( n=61)...
February 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29392967/sedation-in-the-coronary-intensive-care-unit-an-adapted-algorithm-for-critically-ill-cardiovascular-patient
#4
A L Schenone, K Chen, K Andress, M Militello, L Cho
In the current era, cardiovascular intensive care units care for more complex patients who are far sicker than historical post-myocardial infarction patients, and sedation has become a common intervention in these units. Current sedation best practices derive mainly from non-cardiac units which limits their generalization to the critically ill cardiac patient. Thus, a great variability in sedation protocols, especially the selection of sedative agents, is commonly seen in daily practice across cardiac units...
February 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29381371/new-plots-in-the-partnerships-of-contemporary-stemi-care-revival-of-the-m%C3%A3-nage-%C3%A3-trois
#5
Marc A Brouwer, Menko-Jan de Boer
No abstract text is available yet for this article.
January 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29376399/effects-of-chronic-beta-blocker-treatment-on-admission-haemodynamics-in-stemi-patients-treated-with-primary-angioplasty
#6
Vincent Roolvink, Veemal V Hemradj, Jan Paul Ottervanger, Arnoud Wj van 't Hof, Jan-Henk E Dambrink, At Marcel Gosselink, Elvin Kedhi, Harry Suryapranata
BACKGROUND: The association between chronic beta-blocker treatment and haemodynamics at admission in patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention is not well studied. We investigated the impact of chronic beta-blocker treatment on the risk of cardiogenic shock and pre-shock at admission in patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention. METHODS AND RESULTS: A total of 4907 patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention were included in the study...
January 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29376398/spontaneous-coronary-artery-dissection-acute-findings-on-coronary-computed-tomography-angiography
#7
Marysia S Tweet, Nila J Akhtar, Sharonne N Hayes, Patricia Jm Best, Rajiv Gulati, Philip A Araoz
BACKGROUND: The coronary computed tomography angiography features of acute spontaneous coronary artery dissection, an important cause of acute coronary syndrome in young women, have not been assessed. METHODS: The "Virtual" Multicenter Mayo Clinic Spontaneous Coronary Artery Dissection Registry was established in 2010 and includes retrospective and prospective patient data. Retrospective assessment of acute coronary computed tomography angiography images was performed for 14 patients (16 vessels) who had images performed within two days of invasive coronary angiography diagnosis of acute spontaneous coronary artery dissection...
January 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29359586/change-of-bnp-between-admission-and-discharge-after-st-elevation-myocardial-infarction-killip-i-improves-risk-prediction-of-heart-failure-death-and-recurrent-myocardial-infarction-compared-to-single-isolated-measurement-in-addition-to-the-grace-score
#8
Luiz Sergio F Carvalho, Lauro Afonso C Bogniotti, Osorio Luis Rangel de Almeida, Jose C Quinaglia E Silva, Wilson Nadruz, Otavio Rizzi Coelho, Andrei C Sposito
OBJECTIVE: In ST-elevation myocardial infarction, 7-15% of patients admitted as Killip I will develop symptomatic heart failure or decreased ejection fraction. However, available clinical scores do not predict the risk of severe outcomes well, such as heart failure, recurrent myocardial infarction, and sudden death in these Killip I individuals. Therefore, we evaluated whether one vs two measurements of BNP would improve prediction of adverse outcomes in addition to the GRACE score in ST-elevation myocardial infarction/Killip I individuals...
January 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29350536/diagnostic-accuracy-of-functional-imaging-and-biochemical-tests-for-patients-presenting-with-chest-pain-to-the-emergency-department-a-systematic-review-and-meta-analysis
#9
Mario Iannaccone, Sebastiano Gili, Ovidio De Filippo, Salvatore D'Amico, Marco Gagliardi, Maurizio Bertaina, Silvia Mazzilli, Sara Rettegno, Federica Bongiovanni, Paolo Gatti, Fabrizio Ugo, Giacomo G Boccuzzi, Salvatore Colangelo, Silvia Prato, Claudio Moretti, Maurizio D'Amico, Patrizia Noussan, Roberto Garbo, David Hildick-Smith, Fiorenzo Gaita, Fabrizio D'Ascenzo
BACKGROUND: Non-invasive ischaemia tests and biomarkers are widely adopted to rule out acute coronary syndrome in the emergency department. Their diagnostic accuracy has yet to be precisely defined. METHODS: Medline, Cochrane Library CENTRAL, EMBASE and Biomed Central were systematically screened (start date 1 September 2016, end date 1 December 2016). Prospective studies (observational or randomised controlled trial) comparing functional/imaging or biochemical tests for patients presenting with chest pain to the emergency department were included...
January 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29313713/ischemic-and-bleeding-outcomes-after-coronary-artery-bypass-grafting-among-patients-initially-treated-with-a-p2y12-receptor-antagonist-for-acute-coronary-syndromes-insights-on-timing-of-discontinuation-of-ticagrelor-and-clopidogrel-prior-to-surgery
#10
Juan J Russo, Tyler E James, Marc Ruel, Jean-Yves Dupuis, Kuljit Singh, Daniel Goubran, Nikita Malhotra, Fraser Rubens, Aun-Yeong Chong, Benjamin Hibbert, Paul Boland, Diem Tt Tran, Jean-Francois Tanguay, Marie Lordkipanidzé, Louis Perrault, George A Wells, Michael Bourke, Vincent Chan, Derek Yf So
BACKGROUND: Clinical outcomes in acute coronary syndrome patients treated with P2Y12 inhibitors who require urgent coronary artery bypass grafting (CABG) have not been well studied. METHODS: We examined clinical outcomes in acute coronary syndrome patients in relation to the timing of CABG following P2Y12 inhibitor discontinuation (<72 h, 72 h to five days, >5 days). The primary ischemic outcome was a composite of death, reinfarction, need for revascularization, or stroke...
January 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29308660/gender-difference-with-the-use-of-percutaneous-left-ventricular-assist-device-in-patients-undergoing-complex-high-risk-percutaneous-coronary-intervention-from-pvad-working-group
#11
Rajkumar Doshi, Avneet Singh, Rajiv Jauhar, Perwaiz M Meraj
BACKGROUND: The interventional treatment of complex high-risk indicated patients is technically difficult and can result in poor outcomes. Thus, percutaneous left ventricular assist devices are being increasingly used to provide hemodynamic support. No data is available comparing male and female for Complex High-risk Indicated Patients treated with percutaneous left ventricular assist devices. Our goal was to evaluate in-hospital as well as short term outcomes comparing males and females...
January 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29283270/an-east-west-comparison-of-self-care-barriers-in-heart-failure
#12
Shir Lynn Lim, Siew Pang Chan, Kim Yee Lee, Anne Ching, Richard J Holden, Karen F Miller, Alan B Storrow, Carolyn Sp Lam, Sean P Collins
BACKGROUND: Barriers in heart failure self-care contribute to heart failure hospitalizations, but geographic differences have not been well-studied. We aimed to compare self-care barriers in heart failure patients managed at tertiary centers in an Eastern (Singapore) versus a Western (USA) nation. METHODS: Acute heart failure patients were prospectively assessed with a standardized instrument comprising of 47 distinct self-care barriers. The multi-equation generalized structural equation model was used to evaluate for geographic differences in barriers experienced, and association of barriers with outcomes...
December 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29278915/how-is-cardiac-troponin-released-from-injured-myocardium
#13
Johannes Mair, Bertil Lindahl, Ola Hammarsten, Christian Müller, Evangelos Giannitsis, Kurt Huber, Martin Möckel, Mario Plebani, Kristian Thygesen, Allan S Jaffe
Cardiac troponin I and cardiac troponin T are nowadays the criterion biomarkers for the laboratory diagnosis of acute myocardial infarction due to their very high sensitivities and specificities for myocardial injury. However, still many aspects of their degradation, tissue release and elimination from the human circulation are incompletely understood. Myocardial injury may be caused by a variety of different mechanisms, for example, myocardial ischaemia, inflammatory and immunological processes, trauma, drugs and toxins, and myocardial necrosis is preceded by a substantial reversible prelethal phase...
December 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29256635/trends-in-clinical-outcomes-and-survival-following-prehospital-thrombolytic-therapy-given-by-ambulance-clinicians-for-st-elevation-myocardial-infarction-in-rural-sub-arctic-norway
#14
Jan Mannsverk, Terje Steigen, Harald Wang, Pål Morten Tande, Birgitte Mannsverk Dahle, Maret Lajla Nedrejord, Ida Olsen Hokland, Mads Gilbert
BACKGROUND: Prehospital thrombolytic therapy given by ambulance emergency medical services to patients with acute ST-segment elevation myocardial infarction (STEMI) may produce earlier reperfusion than percutaneous coronary intervention. Clinical results from prehospital thrombolytic therapy in rural areas are scarce. METHODS: We studied outcomes during 11 years of a prehospital thrombolytic therapy system in rural sub-arctic Norway. Ambulance personnel gave protocol basic treatment and transmitted electrocardiograms to hospital physicians who made the decision for prehospital thrombolytic therapy...
December 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29249166/safety-and-efficacy-of-rivaroxaban-for-the-secondary-prevention-following-acute-coronary-syndromes-among-biomarker-positive-patients-insights-from-the-atlas-acs-2-timi-51-trial
#15
Serge Korjian, Eugene Braunwald, Yazan Daaboul, Freek Verheugt, Christoph Bode, Michal Tendera, Purva Jain, Alexei Plotnikov, Paul Burton, C Michael Gibson
BACKGROUND: Despite dual antiplatelet therapy, persistent thrombin generation and thrombin-mediated platelet activation account in part for the residual risk of atherothrombotic disease among patients with prior acute coronary syndrome (ACS). Inhibition of thrombin generation among high-risk ACS patients (biomarker-positive ACS) with the factor Xa inhibitor rivaroxaban may limit ongoing thrombus formation and myocardial necrosis and thereby improve clinical outcomes. OBJECTIVES AND METHODS: ATLAS ACS 2-TIMI 51 was a double-blind, placebo-controlled clinical trial that randomized ACS patients to either rivaroxaban 2...
December 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29206050/association-between-short-and-long-sleep-durations-and-cardiovascular-outcomes-a-systematic-review-and-meta-analysis
#16
Chayakrit Krittanawong, Anusith Tunhasiriwet, Zhen Wang, HongJu Zhang, Ann M Farrell, Sakkarin Chirapongsathorn, Tao Sun, Takeshi Kitai, Edgar Argulian
BACKGROUND: A shorter sleep duration has been identified as a risk factor for cardiovascular diseases and increased mortality. It has been hypothesized that a short sleep duration may be linked to changes in ghrelin and leptin production, leading to an alteration of stress hormone production. Here, we conducted a systematic review and meta-analysis to investigate the potential relationship between a sleep duration and cardiovascular disease mortality. METHODS: We conducted a comprehensive search of Ovid Medline In-Process and other non-indexed citations, Ovid MEDLINE, Ovid Embase, Ovid Cochrane Central Register of Controlled Trials, and Scopus from database inception to March 2017...
December 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29199434/a-single-centre-prospective-cohort-study-addressing-the-effect-of-a-rule-in-rule-out-troponin-algorithm-on-routine-clinical-practice
#17
Jack Marjot, Thomas E Kaier, Katherine Henderson, Laura Hunter, Michael S Marber, Divaka Perera
AIMS: In 2015, the European Society of Cardiology introduced new guidelines for the diagnosis of acute coronary syndromes in patients presenting without persistent ST-segment elevation. These guidelines included the use of high-sensitivity troponin assays for 'rule-in' and 'rule-out' of acute myocardial injury at presentation (using a '0 hour' blood test). Whilst these algorithms have been extensively validated in prospective diagnostic studies, the outcome of their implementation in routine clinical practice has not been described...
December 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29199427/predictive-value-of-routine-point-of-care-cardiac-troponin-t-measurement-for-prehospital-diagnosis-and-risk-stratification-in-patients-with-suspected-acute-myocardial-infarction
#18
Martin B Rasmussen, Carsten Stengaard, Jacob T Sørensen, Ingunn S Riddervold, Troels M Hansen, Matthias Giebner, Claus-Henrik Rasmussen, Hans E Bøtker, Christian J Terkelsen
OBJECTIVE: The purpose of this study was to determine the predictive value of routine prehospital point-of-care cardiac troponin T measurement for diagnosis and risk stratification of patients with suspected acute myocardial infarction. METHODS AND RESULTS: All prehospital emergency medical service vehicles in the Central Denmark Region were equipped with a point-of-care cardiac troponin T device (Roche Cobas h232) for routine use in all patients with a suspected acute myocardial infarction...
December 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29412021/cardiogenic-shock-the-next-frontier-in-acute-cardiovascular-care
#19
Christiaan Jm Vrints
No abstract text is available yet for this article.
February 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29219026/improving-long-term-outcomes-of-acute-cardiovascular-syndromes
#20
Christiaan Jm Vrints
No abstract text is available yet for this article.
December 2017: European Heart Journal. Acute Cardiovascular Care
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