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Pediatric Gastroenterology, Hepatology & Nutrition

Josipa Unić, Matea Kovačić, Gordana Jakovljević, Ana Tripalo Batoš, Tonći Grmoja, Iva Hojsak
Inflammatory bowel disease (IBD) is a well-recognized risk factor for thrombotic events in adults but data on children are scarce. In the great majority of adult patients, thrombotic events are usually deep vein thrombosis and pulmonary embolism. Other sites such as jugular veins are extremely rare. We present a case of Lemierre syndrome in an adolescent girl with active ulcerative colitis and discuss possible risk factors. This is the first reported case of severe Lemierre syndrome with thrombus extension to cranial veins in a patient with ulcerative colitis...
July 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Sang-Eun Han, Jiyeon Chang, Seung Sam Paik, Yong Joo Kim
Most solitary gastrointestinal (GI) polyps in children are either inflammatory or hamartomatous. Solitary hyperplastic polyp, sentinel polyp and solitary adenomatous polyp have been occasionally diagnosed in adults, but very rarely reported in Korean children. We recently came across a case with adenomatous polyp in the colon, a case with hyperplastic polyp beneath the gastroesophageal junction, a case with hyperplastic polyp in the prepyloric area, and a case with sentinel polyp in the distal esophagus, which are unusual pathologic types in children...
July 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Young A Kim, Gyung Min Kim, Peter Chun, Eun Ha Hwang, Sang Wook Mun, Yeoun Joo Lee, Jae Hong Park
Purpose: The aim of this study was to describe our treatment experiences with patients who had acute abdomen (AA) with common bile duct (CBD) dilatation. Methods: The treatment outcomes in children with AA and CBD dilatation were retrospectively reviewed. According to the shape of the intrahepatic bile ducts on ultrasonography (US), the origin of the pain was estimated as choledochal cyst (CC) complication or choledocholithiasis in normal CBD. Patients with complicated CC underwent surgery, and patients with choledocholithiasis in a normal appearing CBD underwent symptomatic treatment initially...
July 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Amrita Sinha, Maroun Mhanna, Reema Gulati
Purpose: Treatment of chronic constipation and fecal impaction is usually outpatient and requires high or frequent doses of laxatives. However, there are children who fail outpatient treatments, sometimes repeatedly, and are ultimately hospitalized. We sought to compare the characteristics of the children who failed outpatient treatment and needed inpatient treatment vs those who achieved success with outpatient treatment, in an effort to identify attributes that might be associated with a higher likelihood towards hospitalization...
July 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Hyo-Jeong Jang, Jae Hyun Park, Chun Soo Kim, Sang Lak Lee, Won Mok Lee
Purpose: We investigated fecal calprotectin (FC) levels in preterm infants with and without feeding intolerance (FI), and compared the FC levels according to the type of feeding. Methods: The medical records of 67 premature infants were reviewed retrospectively. The fully enteral-fed infants were classified into two groups; the FI group (29 infants) and the control group (31 infants). Seven infants with necrotizing enterocolitis, sepsis, and perinatal asphyxia were excluded...
July 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Won Seok Jin, Ji Hyoung Park, Kyung In Lim, Hann Tchah, Eell Ryoo
Purpose: Despite the increasing incidence of pediatric Crohn disease (CD) in Korea, data on the characteristics of perianal lesions are scarce. Therefore, we aimed to investigate the characteristics of pediatric CD with accompanying perianal lesions in Korea. Methods: We retrospectively reviewed the medical records of children (age ≤18 years) with confirmed CD at Gachon University Gil Medical Center between 2000 and 2014. Patients were classified into two groups based on the presence or absence of any perianal lesions including skin tags...
July 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Ghassan Ghssein, Ali Salami, Lamis Salloum, Pia Chedid, Wissam H Joumaa, Hadi Fakih
Purpose: Acute gastroenteritis (AGE) is a major cause of morbidity and remains a major cause of hospitalization. Following the Syrian refugee crisis and insufficient clean water in the region, this study reviews the etiological and epidemiological data in Lebanon. Methods: We prospectively analyzed demographic, clinical and routine laboratory data of 198 children from the age of 1 month to 10 years old who were admitted with the diagnosis of AGE to a private tertiary care hospital located in the district of Nabatieh in south Lebanon...
July 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Michelle Li Nien Tan, Leilani Muhardi, Seksit Osatakul, Badriul Hegar, Yvan Vandenplas, Thomas Ludwig, Jacques Bindels, Eline M Van der Beek, Seng Hock Quak
Purpose: Lactose intolerance (LI) is perceived to be frequent in Asia and has been reported to have considerable impact on dietary intake, nutritional status and the quality of life. We aimed to gather information from healthcare professionals on the perceived incidence, diagnosis and management of LI in 1 to 5 year old children in Southeast Asia. Methods: An anonymous electronic survey was sent randomly among healthcare professionals registered in the database of the pediatric societies in Thailand, Indonesia, and Singapore between June and October 2016...
July 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Ahmet Basturk, Reha Artan, Aygen Yılmaz, Mustafa T Gelen
Purpose: The aim of this study is to determine the involvement of the upper gastrointestinal system (GIS) in patients diagnosed with Crohn's disease (CD), ulcerative colitis (UC), and non-inflammatory bowel disease (IBD) and to compare their differences. Methods: This study included patients aged between 2 and 18 years who underwent colonoscopy and esophagogastroduodenoscopy (EGD) for the first time due to the prediagnosis of IBD. In EGD, samples were taken from duodenum, antrum, corpus, and esophagus; and gastritis, duodenitis, and esophagitis were identified through histopathologic examination...
July 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Suk Jin Hong
Infant formula is classified into standard cow's milk-based and special formulas. This review aimed at summarizing the types of special milk formulas currently sold in Korea, and the appropriate indications for the use of these formulas; lactose free formula, soy-based formula, protein hydrolysate formula, amino acid-based formula, preterm formula, medium chain triglyceride formula, low-phosphorus formula, protein-energy-enriched formula, and formulas for inborn errors of metabolism.
July 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Ji Eun Jeong, Kyung Moon Kim, Hye Lim Jung, Jae Won Shim, Deok Soo Kim, Jung Yeon Shim, Moon Soo Park, Soo Kyung Park
Epstein-Barr virus (EBV) infection can be presented with various clinical manifestations and different levels of severity when infected. Infectious mononucleosis, which is most commonly caused by EBV infection in children and adolescents, is a clinical syndrome characterized by fatigue, malaise, fever, sore throat, and generalized lymphadenopathy. But rarely, patients with infectious mononucleosis may present with gastrointestinal symptoms and complicated by gastritis, splenic infarction, and splenic rupture...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Youngmin Youn, Sang Won Lee, Hyun-Hae Cho, Sanghui Park, Hae-Sun Chung, Jeong Wan Seo
Nowadays, Klebsiella oxytoca is described as a causative organism for antibiotic-associated hemorrhagic colitis (AAHC). Here we report two cases of pediatric AAHC, from which K. oxytoca was cultured after starting amoxicillin-clavulanate or amoxicillin treatment. The patients developed severe abdominal pain and a large amount of bloody diarrhea. K. oxytoca was obtained in intestinal fluid culture of a boy through the colonoscopy. On the other hand, colonic tissue culture and intestinal fluid culture were negative of the other patient...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Helena Ferreira, Raquel Nuñez Ramos, Cinthia Flores Quan, Susana Redecillas Ferreiro, Vanessa Cabello Ruiz, Javi Juampérez Goñi, Jesus Quintero Bernabeu, Oscar Segarra Cantón, Marina Álvarez Beltran
Chylomicron retention disease, also known as Anderson's disease, is a rare hereditary hypocholesterolemic disorder, recessive inherited, characterized by nonspecific symptoms as abdominal distension, steatorrhea, and vomiting associated with failure to thrive. We describe a patient with failure to thrive, chronic diarrhea and steatorrhea who the diagnosis of chylomicron retention disease was established after several months of disease progression. The genetic study confirmed a homozygosity mutation in SAR1B gene, identifying a mutation never previous described [c...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Eun Hye Park, Min-Su Oh, Sorina Kim, Juyeon Lee, Ki Soo Kang
Purpose: For 3 consecutive years from 2012-2014, we analyzed the causative factors for why the Jeju Island had the highest obesity prevalences of school children among the 15 provinces in Korea. Methods: From our analysis of 28,026 elementary school children with obesity or normal weight in the 15 provinces, we analyzed 12 factors related to eating habits, exercise habits, lifestyle, and mental health. The differences between the obese and normal weight children were researched...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
José Vicente Arcos-Machancoses, Cristina Molera Busoms, Ecaterina Julio Tatis, María Victoria Bovo, Jesús Quintero Bernabeu, Javier Juampérez Goñi, Vanessa Crujeiras Martínez, Javier Martin de Carpi
Purpose: Classical criteria for diagnosis of autoimmune hepatitis (AIH) are intended as research tool and are difficult to apply at patient's bedside. We aimed to study the accuracy of simplified criteria and the concordance with the expert diagnosis based on the original criteria. Methods: A cohort of children under study for liver disorder was selected through consecutive sampling to obtain the prevalence of AIH within the group of differential diagnoses. AIH was defined, based on classical criteria, through committee review of medical reports...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Fatih Battal, Hakan Türkön, Nilüfer Aylanç, Hakan Aylanç, Şule Yıldırım, Nazan Kaymaz, Sema Uysal
Purpose: The prevalence of obesity has significantly increased among children and adolescents worldwide and is becoming an important health care problem in parallel with the increased prevalence of obesity pediatric non-alcoholic fatty liver disease. Betatrophin is a newly define hormone that is commonly secreted by liver and plays role in glucose tolerance. This study aimed to investigate the relationship between serum betatrophin levels and non-alcoholic fatty liver disease in obese children...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Atchariya Chanpong, Seksit Osatakul
Purpose: Functional constipation (FC) is a common gastrointestinal (GI) problem affecting children's well-being and quality of life. Although polyethylene glycol (PEG) is recommended as the first line therapy, it is not always applicable in lower socioeconomic populations. Hence, this study aimed to compare clinical courses of FC in children treated with different medications in order to identify prognostic factors related to treatment outcomes. Methods: We reviewed the medical records of patients aged ≤15 years diagnosed with FC according to the Rome IV criteria from 2007 to 2015 at the GI clinic, Songklanagarind Hospital...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Reema Gulati, Arpitha Komuravelly, Stephen Leb, Maroun J Mhanna, Abdullah Ghori, Janeen Leon, Robert Needlman
Purpose: Rome criteria are considered the gold standard for diagnosing functional constipation. The modified Bristol stool form scale (m-BSFS) was validated to measure stool form in children. However, neither the potential use of the m-BSFS as a tool to facilitate the diagnosis of potential constipation, nor the agreement between m-BSFS and stool consistency by Rome has been studied. Our objective is to determine if m-BSFS is a reliable tool to facilitat detection of constipation; and the agreement between stool form by m-BSFS and hard stool criteria in Rome...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Pooja Semwal, Raj Kumar Gupta, Rahul Sharma, Kapil Garg
Purpose: Celiac disease is a common non-communicable disease with varied presentations. Purpose of this study was to find the duodeno-endoscopic features in celiac disease and to compare duodeno-endoscopic and histological findings between typical and atypical celiac disease in children. Methods: Hospital based observational study was conducted at Sir Padampat Mother and Child Health Institute, Jaipur from June 2015 to May 2016. Patients were selected and divided in two groups- typical and atypical celiac disease based upon the presenting symptoms...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
Yeoun Joo Lee
Increased awareness of the importance of nutrition among hospitalized children has increased the use of nutrition screening tool (NST). However, it is not well known the NST for hospitalized children. Therefore, the purpose of this study is to understand the past and present state of adult and child NST and discuss the pros and cons of each NST.
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
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