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Rambam Maimonides Medical Journal

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https://www.readbyqxmd.com/read/28459665/roderigo-lopez-physician-in-chief-to-queen-elizabeth-i-of-england
#1
George M Weisz, Donatella Lippi
Roderigo Lopez, former Physician-in-Chief to Queen Elizabeth I of England, was a controversial figure in his time and continues to be the subject of controversy. Much has been written about his religious practice, politics, and guilt, or lack thereof, with regard to charges of treason to the Crown. However, the fact remains that Lopez was the only physician to the Crown to be sentenced to death. All evidence points to an anti-Semitic mindset that played in the background. Yet Lopez so endeared himself to the Queen that although he was indeed sentenced to death, almost all of his property was restored to his family...
May 1, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28459664/the-development-of-robotic-technology-in-cardiac-and-vascular-interventions
#2
Ali Pourdjabbar, Lawrence Ang, Ryan R Reeves, Mitul P Patel, Ehtisham Mahmud
Robotic technology has been used in cardiovascular medicine for over a decade, and over that period its use has been expanded to interventional cardiology and percutaneous coronary and peripheral vascular interventions. The safety and feasibility of robotically assisted interventions has been demonstrated in multiple studies ranging from simple to complex coronary lesions, and in the treatment of iliofemoral and infrapopliteal disease. These studies have shown a reduction in operator exposure to harmful ionizing radiation, and the use of robotics has the intuitive benefit of alleviating the occupational hazard of operator orthopedic injuries...
April 26, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28448252/hypothyroidism-in-carcinoma-of-the-tongue-with-adjuvant-treatment
#3
Sabita Kumari, Jonathan Gondi, Hemantkumar Nemade, L M Chandra Sekhara Rao, Deleep Gudipudi, T Subramanyeshwar Rao
OBJECTIVE: The objective of this study was to evaluate the incidence of hypothyroidism with adjuvant treatment in oral tongue carcinoma patients treated primarily with surgery. MATERIALS AND METHODS: A retrospective review was carried out to analyze hypothyroidism incidence and its relation to adjuvant treatment (radiation/radio-chemotherapy) in oral tongue carcinoma after the primary surgical ablation and neck dissection. Hypothyroidism was analyzed in relation with dose of radiation, gender, and adjuvant treatment modality...
March 29, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467769/fear-of-vaginal-penetration-in-the-absence-of-pain-as-a-separate-category-of-female-sexual-dysfunction-a-conceptual-overview
#4
David Rabinowitz, Lior Lowenstein, Ilan Gruenwald
Functional sexual pain disorders in women are a particular challenge to the gynecologist, inasmuch as phobic avoidance and guarding on the part of the patient lead to difficulties in the gynecological examination and diagnosis. In some such cases examination may even be impossible. Vaginismus is the commonly diagnosed etiology of such cases. This article offers an overview of vaginismus and approaches to its treatment but also examines a subset of penetration-avoidant patients who do not appear to have a pain component...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467768/gnrh-agonist-triggering-of-ovulation-replacing-hcg-a-30-year-old-revolution-in-ivf-practice-led-by-rambam-health-care-campus
#5
REVIEW
Shahar Kol, Ofer Fainaru
Final oocyte maturation is a crucial step in in vitro fertilization, traditionally achieved with a single bolus of human chorionic gonadotropin (hCG) given 36 hours before oocyte retrieval. This bolus exposes the patient to the risks of ovarian hyperstimulation syndrome (OHSS), particularly in the face of ovarian hyper-response to gonadotropins. Although multiple measures were developed to prevent OHSS, gonadotropin-releasing hormone (GnRH) agonist triggering is now globally recognized as the best approach to achieve this goal...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467767/impact-of-endometrial-preparation-protocols-for-frozen-embryo-transfer-on-live-birth-rates
#6
Maria Cerrillo, Leyre Herrero, Alfredo Guillén, Mercedes Mayoral, Juan Antonio García-Velasco
BACKGROUND: It has been reported that a natural cycle (NC) is similar to or even better than hormone replacement therapy (HRT) in patients with regular cycles who undergo frozen embryo transfer (FET). Hundreds of FETs are managed yearly in our clinic. Scheduling these cycles is critical in a busy unit like ours. This is why we have to prove if a NC really shows a better outcome than other endometrium preparation protocols. METHODS: Hence we carried out a prospective study between June 2011 and June 2012, which included 530 patients (570 FET cycles) randomly allocated to two study groups: Group 1 (n=280 cycles), artificial cycle (HRT); or group 2 (n=290 cycles), natural cycle...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467766/was-the-military-operation-protective-edge-a-risk-factor-for-pregnancy-complications
#7
Ohad Gluck, Yossi Mizrachi, Sophia Leytes, Jacob Bar, Michal Kovo
OBJECTIVE: During July-August 2014, the military operation "Protective Edge" presented Israel with a threat of missile attacks. We aimed to investigate the influence of the "Protective Edge" operation on the rate of pregnancy complications among the population exposed to missile attacks, compared to the population not exposed. STUDY DESIGN: This was a retrospective study. Pregnancy outcomes were compared between women who during pregnancy were exposed to the stress of the military operation (exposed group, n=4,673) and gave birth at the Wolfson Medical Center, and women who gave birth in the previous year (unexposed group, n=4,735)...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467765/rambam-hospital-is-the-birthplace-of-the-modern-version-of-transvaginal-ultrasound
#8
Ilan E Timor-Tritsch
The worldwide use of the transvaginal scanning route has revolutionized obstetrical and gynecologic imaging. The long, slow, and at times challenging aspects of its acceptance by the obstetrical and gynecologic community are the subject of this article. From its inception to its recent use, the dedicated doctors in the Department of Obstetrics and Gynecology at Rambam Medical Center, Haifa, Israel, were instrumental in conceiving and then collaborating with an Israeli manufacturer in the construction and worldwide use of the transvaginal ultrasound probe, resulting in the now well-known field of transvaginal sonography...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467764/anovulatory-patients-demonstrate-a-sharp-decline-in-lh-levels-upon-gnrh-antagonist-administration-during-ivf-cycles
#9
Linoy Segal, Ofer Fainaru, Shahar Kol
To evaluate the decrease in luteinizing hormone (LH) levels following gonadotropin-releasing hormone (GnRH) antagonist administration in in vitro fertilization (IVF) cycles, data were retrospectively collected from 305 consecutive IVF or intracytoplasmic sperm injection (ICSI) cycles of patients who underwent ovarian stimulation with gonadotropins and were treated with GnRH antagonist for the prevention of premature luteinization. We compared the percent change in LH concentration from stimulation start to that observed before ovulation triggering in patients with or without anovulation...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467763/surgical-updates-in-the-treatment-of-pelvic-organ-prolapse
#10
REVIEW
Julia Geynisman-Tan, Kimberly Kenton
Pelvic organ prolapse affects approximately 8% of women, and the demand for pelvic organ prolapse surgery is expected to increase by nearly 50% over the next 40 years. The surgical techniques used to correct pelvic organ prolapse have evolved over the last 10 years, with multiple well-designed studies addressing the risks, outcomes, reoperation rates, and optimal surgical approaches. Here we review the most recent evidence on the route of access, concomitant procedures, and synthetic materials for augmenting the repair...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467762/is-a-blanket-elective-single-embryo-transfer-policy-defensible
#11
REVIEW
Eli Y Adashi, Norbert Gleicher
For the purpose of reducing maternal and neonatal morbidity, elective single transfer (eSET) in in vitro fertilization (IVF) was first proposed in 1999. The purpose of this review is to summarize recent oral debate between a proponent and an opponent of expanded eSET utilization in an attempt to determine whether a blanket eSET policy, as is increasingly considered, is defensible. While eSET is preferable when possible, and agreed upon by provider and patient, selective double embryo transfer (DET) must be seriously entertained if deemed more appropriate or is desired by the patient...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467761/review-of-robotic-surgery-in-gynecology-the-future-is-here
#12
REVIEW
Roy Lauterbach, Emad Matanes, Lior Lowenstein
The authors present a systematic review of randomized and observational, retrospective and prospective studies to compare between robotic surgery as opposed to laparoscopic, abdominal, and vaginal surgery for the treatment of both benign and malignant gynecologic indications. The comparison focuses on operative times, surgical outcomes, and surgical complications associated with the various surgical techniques. PubMed was the main search engine utilized in search of study data. The review included studies of various designs that included at least 25 women who had undergone robotic gynecologic surgery...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467760/obstetric-anal-sphincter-injuries-oasis-in-israel-a-review-of-the-incidence-and-risk-factors
#13
REVIEW
Shimon Ginath, Yossi Mizrachi, Jacob Bar, Alexander Condrea, Michal Kovo
Obstetric anal sphincter injuries (OASIs) following vaginal deliveries are the main reason for subsequent development of anal incontinence in women. The diagnosis of such tears is crucial for treating and preventing such a grave sequela. The reported rate of OASIs in Israel was between 0.1% and 0.6%, out of all vaginal births, which is 10-fold lower than that reported in Europe and the United States. Structured hands-on training in repair of OASIs in seven medical centers in Israel significantly increased the detection rate of third-degree perineal tears...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467759/nucleated-red-blood-cells-as-a-marker-of-acute-and-chronic-fetal-hypoxia-in-a-rat-model
#14
Victoria K Minior, Brian Levine, Asaf Ferber, Seth Guller, Michael Y Divon
OBJECTIVE: To examine the relationship between duration of fetal hypoxia, nucleated red blood cell (NRBC) count, and fetal growth. METHODS: Pregnant rats were exposed to a severe hypoxia (9.5%-10% O2) for varying time intervals (2, 6, 12, 24, 48, and 120 hours; n=4 for each time interval) immediately prior to delivery at term. Normoxic controls were exposed to room air (21% O2) and matched for all other study variables (n=4 rats for each time interval). Pups were delivered via hysterotomy while maintaining exposure gas concentrations...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467758/protective-effect-of-n-acetyl-cysteine-nac-in-lipopolysaccharide-lps-associated-inflammatory-response-in-rat-neonates
#15
Nizar Khatib, Zeev Weiner, Yuval Ginsberg, Nibal Awad, Ron Beloosesky
OBJECTIVE: Increased inflammatory response may be associated with adverse clinical outcomes, especially in the neonatal period. The aims of this study were to determine whether N-acetyl-cysteine (NAC), an anti-inflammatory agent, attenuates the inflammatory response in young rats and to determine the most effective route of administration. METHODS: Four groups of Sprague-Dawley rats (in each group four rats) were studied at 30 days of age. One hour following intraperitoneal (IP) injection of lipopolysaccharide 50 μg/kg, the rats were randomized to subcutaneous (SC), per os (PO), or intraperitoneal (IP) injection of NAC 300 mg/kg, or saline...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467757/the-female-urinary-microbiota-microbiome-clinical-and-research-implications
#16
Linda Brubaker, Alan J Wolfe
The changing science of the urinary microbiota and microbiome has both clinical and research implications. This review paper provides an overview of the state of this science, as well as a discussion of the potential for prevention, diagnosis, and treatment of human disease. The history of techniques used for clinical detection of infection are placed into context along with the modern methods of bacterial detection and identification.
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28467756/maternal-inflammation-fetal-brain-implications-and-suggested-neuroprotection-a-summary-of-10-years-of-research-in-animal-models
#17
REVIEW
Yuval Ginsberg, Nizar Khatib, Zeev Weiner, Ron Beloosesky
A growing body of evidence implies that maternal inflammation during pregnancy is associated with increased risk of neurodevelopmental disorders in the offspring. The pathophysiological mechanisms by which maternal inflammation evokes fetal brain injury and contributes to long-term adverse neurological outcomes are not completely understood. In this review, we summarize 10 years of our research experience on maternal inflammation and the implications upon the fetal/offspring brain. We review our findings regarding the underlying mechanisms that connects maternal inflammation and fetal brain injuries (e...
April 28, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28178444/remembering-eliahu-de-luna-montalto-1567-1616
#18
George M Weisz, Donatella Lippi
Born in Portugal and the son of Marranos (Christianized Jews from Spain), Eliahu de Luna Montalto lived during a particularly harsh period for the Jewish people. Throughout Europe, the situation for Jews was unfavorable; laws had been passed forbidding them to live in England for the past 300 years, and for the past 200 years in France. Additionally, in France, while Jews were permitted to study at some universities, the practice of medicine was forbidden to them. It is within this context that Eliahu de Luna Montalto, who had returned to his original faith (Judaism), was recruited to the French court...
January 30, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28178443/abstracts-from-the-thirteenth-rambam-research-day-december-22-2016
#19
(no author information available yet)
No abstract text is available yet for this article.
January 30, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28178442/author-s-reply-to-a-few-suggestions-for-preventing-failure-of-ultrasound-guided-blocks-for-below-the-shoulder-surgery
#20
LETTER
Anatoli Stav
No abstract text is available yet for this article.
January 30, 2017: Rambam Maimonides Medical Journal
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