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Rambam Maimonides Medical Journal

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https://www.readbyqxmd.com/read/29215980/unilateral-vocal-cord-paralysis-of-a-great-jewish-opera-singer
#1
Irit Duek, Jacob T Cohen, Ziv Gil
George London was one of the most compelling vocal artists of the early twentieth century. At the age of 47, the great bass-baritone retired from singing. It has been suggested that the premature ending of his operatic career was due to unilateral vocal cord palsy (UVCP). When London retired, the common belief was that this UVCP was caused by viral hepatitis, although there is no evidence to support such an etiology. London's medical records eliminate the possible etiology of a neck neoplasm, and the long period of time between a heart attack he experienced and his diagnosis of UVCP makes a cardiovascular etiology an unlikely causative factor...
December 6, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29406849/abstracts-from-the-fourteenth-rambam-research-day-december-7-2017
#2
Shraga Blazer, Ehud Klein
No abstract text is available yet for this article.
January 29, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29406848/unilateral-vocal-cord-paralysis-of-a-great-jewish-opera-singer
#3
Irit Duek, Jacob T Cohen, Ziv Gil
George London was one of the most compelling vocal artists of the early twentieth century. At the age of 47, the great bass-baritone retired from singing. It has been suggested that the premature ending of his operatic career was due to unilateral vocal cord palsy (UVCP). When London retired, the common belief was that this UVCP was caused by viral hepatitis, although there is no evidence to support such an etiology. London's medical records eliminate the possible etiology of a neck neoplasm, and the long period of time between a heart attack he experienced and his diagnosis of UVCP makes a cardiovascular etiology an unlikely causative factor...
January 29, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29406847/outer-limits-of-biotechnologies-a-jewish-perspective
#4
John D Loike, Alan Kadish
A great deal of biomedical research focuses on new biotechnologies such as gene editing, stem cell biology, and reproductive medicine, which have created a scientific revolution. While the potential medical benefits of this research may be far-reaching, ethical issues related to non-medical applications of these technologies are demanding. We analyze, from a Jewish legal perspective, some of the ethical conundrums that society faces in pushing the outer limits in researching these new biotechnologies.
January 29, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29406846/six-values-never-to-silence-jewish-perspectives-on-nazi-medical-professionalism
#5
REVIEW
Jacob M Kolman, Susan M Miller
An ideological case study based on medical profession norms during the Third Reich will be used to exemplify the importance of diversity in the manifestations of professional ethics. The German professional medical community banned their Jewish colleagues from treating German citizens. This included legally mandated employment discrimination and outright censure which led to a professional ethic devoid of diverse voices. While the escalation to the T-4 program and medicalized genocide was influenced by many causes, the intentional, ethnocentric-based exclusion of voices was an important contributing element to the chronicled degradation of societal mores...
January 29, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29406845/learning-from-job-a-rare-genetic-disease-and-lessons-of-biblical-proportions
#6
REVIEW
Joshua D Milner
Dominant negative mutations in STAT3, a critical signaling molecule and transcription factor in multiple organ systems, lead to a rare monogenic disease called the STAT3 loss-of-function, autosomal dominant hyper-IgE syndrome (STAT3LOF AD-HIES). The original name for this syndrome, Job's syndrome, was derived from the observation that patients had a propensity to develop skin boils, reminiscent of the affliction cast upon the biblical Job. Many fascinating observations have been made regarding the pathogenesis of the disease and the role STAT3 plays in human health and disease...
January 29, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29406844/an-insight-into-the-effect-of-exercises-on-the-prevention-of-osteoporosis-and-associated-fractures-in-high-risk-individuals
#7
REVIEW
Helen Senderovich, Andrew Kosmopoulos
The purpose of this review was to investigate what type of exercises can potentially prevent osteoporosis (OP) and its associated fractures in high-risk populations. MEDLINE was searched for work relevant to various types of exercises used to prevent osteoporotic fractures in high-risk population, from the year 1995 onwards. Twelve articles were identified, and, from them, four were deemed suitable to the objective. The studies reviewed show that various types of exercise are effective and safe in preventing the onset of OP...
January 29, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29406843/factors-affecting-surgical-decision-making-a-qualitative-study
#8
Caroline Gunaratnam, Mark Bernstein
BACKGROUND: Guidelines and Class 1 evidence are strong factors that help guide surgeons' decision-making, but dilemmas exist in selecting the best surgical option, usually without the benefit of guidelines or Class 1 evidence. A few studies have discussed the variability of surgical treatment options that are currently available, but no study has examined surgeons' views on the influential factors that encourage them to choose one surgical treatment over another. This study examines the influential factors and the thought process that encourage surgeons to make these decisions in such circumstances...
January 29, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29406842/a-unique-publication-model-that-works
#9
EDITORIAL
Shraga Blazer
No abstract text is available yet for this article.
January 29, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29135419/the-risk-of-cancer-might-be-lower-than-we-think-alternatives-to-lifetime-risk-estimates
#10
Gilat L Grunau, Shay Gueron, Boris Pornov, Shai Linn
BACKGROUND: Estimates of lifetime cancer risk are commonly used in the clinical setting and in health-care evaluations. These measures are based on lifetime cancer risk estimates and may create an unrealistically frightening perception of cancer risk for an individual. We suggest using two new measures of cancer risk to complement the cancer lifetime risk measure, namely estimates of cancer risk from birth to a specific age or from a specific age to life expectancy. METHODS: We calculated risks using incidence density data from the Israel National Cancer Registry of 2013, applying a well-known formula for calculating risk, for a follow-up time...
October 16, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29059046/artificial-sperm-new-horizons-in-procreation
#11
REVIEW
Gilad Amiel, Valentin Shabataev, Raanan Tal
Azoospermia, the absence of any sperm cells from the ejaculated semen, poses a real challenge to the fertility urologist. While there are options to create happy families for azoospermic couples, such as the use of donor sperm and adoption, most couples still want to have genetically related offspring. Advances in urology, gynecology, and fertility laboratory technologies allow surgical sperm retrieval in azoospermic men and achievement of live births for many, but not all azoospermic couples. At present, there are extensive research efforts in several directions to create new fertility options by creating "artificial sperm cells...
October 16, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29059045/update-on-screening-for-urological-malignancies
#12
REVIEW
Gilad Amiel, Azik Hoffman, Elizabeth E Half
Urological malignancies are a major source of morbidity and mortality in men over 40. Screening for those malignancies has a potential benefit of reducing both. However, even after more than two decades of screening for prostate cancer, the implications of most resulting information are still a matter of debate. Controversy extends over several aspects of prostate cancer screening programs, including age of onset, defining populations at risk, most appropriate intervals, as well as the optimal methods to be used for screening...
October 16, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29059044/expanding-the-utilization-of-robotic-procedures-in-urologic-surgery
#13
REVIEW
Gilad Amiel, Tareq Aro, Michael Mullerad, Gilad E Amiel
Although the word "robot" was coined in 1921, only close to 70 years later were robotic devices developed to assist during surgery. Urology has always been at the forefront of endoscopic, minimally invasive, and robotic developments in medicine. Robotic prostatectomy signaled the emerging role of robotic surgery in urology, but since then it has been applied to every urologic laparoscopic procedure.
October 16, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29059043/the-urology-residency-program-in-israel-results-of-a-residents-survey-and-insights-for-the-future
#14
Arnon Lavi, Sharon Tzemah, Anan Hussein, Ibrahim Bishara, Nikolay Shcherbakov, Genady Zelichenko, Alon Mashiah, Michael Gross, Michael Cohen
OBJECTIVE: Urology practice has undergone several changes in recent years mainly related to novel technologies introduced. We aimed to get the residents' perspective on the current residency program in Israel and propose changes in it. METHODS: A web-based survey was distributed among urology residents. RESULTS: 61 residents completed the survey out of 95 to whom it was sent (64% compliance). A total of 30% replied that the 9 months of mandatory general surgery rotation contributed to their training, 48% replied it should be shortened/canceled, and 43% replied that the Step A exam (a mandatory written certifying exam) in general surgery was relevant to their training...
October 16, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28914602/initial-clinical-experience-with-a-modulated-holmium-laser-pulse-moses-technology-does-it-enhance-laser-lithotripsy-efficacy
#15
Gilad Amiel, Michael Mullerad, Jonatan R A Aguinaga, Tareq Aro, Alexander Kastin, Oleg Goldin, Alexander Kravtsov, Akram Assadi, Shadie Badaan, Gilad E Amiel
OBJECTIVE: The Lumenis(®) High-power Holmium Laser (120H) has a unique modulated pulse mode, Moses™ technology. Moses technology modulates the laser pulse to separate the water (vapor bubble), then deliver the remaining energy through the bubble. Proprietary laser fibers were designed for the Moses technology. Our aim was to compare stone lithotripsy with and without the Moses technology. METHODS: We designed a questionnaire for the urologist to fill immediately after each ureteroscopy in which the Lumenis 120H was used...
October 16, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28872454/review-of-the-clinical-approaches-to-the-use-of-urine-based-tumor-markers-in-bladder-cancer
#16
REVIEW
Timothy Clinton, Yair Lotan
Bladder cancer is a common disease with a stable incidence for the past few decades despite advancements in molecular and genetic determinants of cancer development and progression. Cystoscopy remains the standard for detection and surveillance of bladder cancer, but it is an invasive and potentially costly procedure. With the knowledge of molecular alterations associated with bladder cancer numerous urine-based tumor markers have become commercially available. These urine markers have been evaluated in all clinical scenarios for the detection of bladder cancer including screening, hematuria, atypical cytology evaluation, and surveillance, but given the relative lack of impactful trials they are not routinely utilized...
October 16, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28872453/allium-stents-a-novel-solution-for-the-management-of-upper-and-lower-urinary-tract-strictures
#17
REVIEW
Gilad Amiel, Zaher Bahouth, Boaz Moskovitz, Sarel Halachmi, Ofer Nativ
Stents are widely use in endoscopic urological procedures. One of the most important indications is the treatment of urinary tract strictures. Allium™ Medical has introduced several types of stents for the treatment of different types of urinary tract strictures, based on anatomic location. All the stents are made of nitinol and coated with a co-polymer that reduces encrustations. These stents are self-expandable and have a large caliber and a high radial force. They have different shapes, designed especially for the treatment of each type of stricture...
October 16, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28777073/multimodality-image-fusion-with-psma-pet-ct-and-high-intensity-focused-ultrasound-focal-therapy-for-primary-diagnosis-and-management-of-prostate-cancer-a-planned-research-initiative
#18
Gilad Amiel, Marcia C Javitt, Alexander Kravtsov, Zohar Keidar, Sobhi Abadi, Gilad E Amiel
Recent developments in diagnostic imaging herald a new approach to diagnosis and management of prostate cancer. Multimodality fusion that combines anatomic with functional imaging data has surpassed either of the two alone. This opens up the possibility to "find and fix" malignancy with greater accuracy than ever before. This is particularly important for prostate cancer because it is the most common male cancer in most developed countries. This article describes technical advances under investigation at our institution and others using multimodality image fusion of magnetic resonance imaging (MRI), transrectal ultrasound (TRUS), and PSMA PET/CT (defined as the combination of prostate-specific membrane antigen [PSMA], positron emission tomography [PET], and computed tomography [CT]) for personalized medicine in the diagnosis and focal therapy of prostate cancer with high-intensity focused ultrasound (HiFUS)...
October 16, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/29035696/the-reliability-of-surgical-apgar-score-in-predicting-immediate-and-late-postoperative-morbidity-and-mortality-a-narrative-review
#19
Abhijit Nair, Aanchal Bharuka, Basanth Kumar Rayani
Surgical Apgar Score is a simple, 10-point scoring system in which a low score reliably identifies those patients at risk for adverse perioperative outcomes. Surgical techniques and anesthesia management should be directed in such a way that the Surgical Apgar Score remains higher to avoid postoperative morbidity and mortality.
October 13, 2017: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/28786810/open-communication-and-discussion-facilitate-reconciliation-the-promise-fulfilled
#20
EDITORIAL
Shraga Blazer
No abstract text is available yet for this article.
July 31, 2017: Rambam Maimonides Medical Journal
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