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Caspian Journal of Internal Medicine

Kazem Anvari, Masoumeh Gharib, Amir Hossein Jafarian, Amin Saburi, Seyed Alireza Javadinia
Background: Melanoma is a neoplasm derived commonly from melanocytic cells of skin. Although coetaneous presentation of malignant melanoma is easily recognizable, the presentation of melanoma in other organs is so confusing. In particular, when it metastasizes to other organs, many bizarre figures and unusual organs may be involved. In this report, we present a case of primary duodenal malignant melanoma. Case Presentation: A 68-year-old man presented with a history of iron deficiency anemia...
2018: Caspian Journal of Internal Medicine
Ali Torkaman, Alireza Yousof Gomrokchi, Omid Elahifar, Pooyan Barmayoon, Seyedeh Fahimeh Shojaei
Background: Bilateral rupture of the patellar tendon is a very rare injury, which takes place in relation to chronic systemic diseases. These injuries are known causes. Some of these causes are particular in patellar tendon rupture and another are in quadriceps tendon rupture. Case presentation: 70-year-old diabetic man with simultaneous bilateral patellar tendon disruption of proximal insertion without trauma, receiving long-term hemodialysis. Conclusions: In the present study, we report a case of patellar tendon rupture that has two differences with literature: first, renal failure is a known risk factor for quadriceps tendon rupture, and secondly, the prevalent age of patellar tendon rupture is less than 40 years...
2018: Caspian Journal of Internal Medicine
Kaouther Maatallah, Ines Mahmoud, Safa Belghali, Kawther Ben Abdelghani, Olfa Saidane, Elyes Bouajina, Ahmad Laatar, Rawdha Tekaya, Leila Abdelmoula
Background: Hip involvement in ankylosing spondylitis (AS) is a common extraspinal arthritic manifestation, which is associated to a worse functional outcome. Little data are available on the effectiveness of conservative treatment strategies. The TNF inhibitors have been proven effective on AS activity parameters. Their structural effect on hip disease however, little is studied. Case presentation: We describe four new cases of reparative changes of a damaged hip joint after treatment with TNF inhibitors...
2018: Caspian Journal of Internal Medicine
Belma Kalaycı, Turgut Karabag, Turgay Erten, Tunahan Akgun
Background: Lead-related infections that might develop after pacemaker implantation associated with high mortality and morbidity rates are challenging to manage and pose high-cost. Patients with lead-related infections usually present with fever, chills and fatigue and the treatment can be challenging unless the implant system is extracted. Case presentation: A 66-year old male patient who underwent dual chamber pacemaker and implantable cardioverter defibrillator was admitted to the emergency service with a six-week history of complaints of hiccups and fever...
2018: Caspian Journal of Internal Medicine
Hamdi Shafi, Masomeh Ilkhani, Zeinab Darabi Ahangar, Masomeh Bayani
Background: One of the lithotripsy complications is urinary tract infection (UTI) and sepsis after extracorporeal shock wave lithotripsy (ESWL). The aim was to study the prophylactic effect of antibiotics on UTI after ESWL. Methods: This randomized double-blind clinical trial was carried out on 600 patients admitted to Babol Clinic hospital in 2014-2015. Patients were randomly divided into treatment group (receiving 200 mg ofloxacin and control group (receiving placebo...
2018: Caspian Journal of Internal Medicine
Hadi Sorkhi, Raheleh Behzadi, Neda Joghtaei, Mohammad Poornasrollah, Ali Bijani
Background: Measurement of glomerular filtration rate (GFR) and monitoring of it in any patient on nephrotoxic drugs is very important. Recently, cystatin C (cys-C) has been introduced as a better marker for determining and monitoring renal function than creatinine especially in a mild decrease of GFR. This study was done to assess the change of GFR measurement based on serum Cys-C and creatinine and their comparison in children with acute pyelonephritis on amikacin. Methods: All children with acute pyelonephritis who were admitted in Nephrology ward were enrolled in this study...
2018: Caspian Journal of Internal Medicine
Ghadam Ali Talebi, Payam Saadat, Yahya Javadian, Mohammad Taghipour
Background: Generally, conservative interventions including physiotherapy modalities and manual therapy have been recommended in the management of carpal tunnel syndrome (CTS), but this subject has not been studied in diabetic patients with CTS. Therefore the aim of this study was to investigate the effects of manual therapy on diabetic patients with CTS. Methods: Thirty diabetic patients with CTS were randomly divided into two equal groups: modality group and manual therapy group...
2018: Caspian Journal of Internal Medicine
Ali Vasheghani-Farahani, Fatemeh Kazemnejad, Khosro Sadeghniiat-Haghighi, Soleil Saadat, Parya Tavakolipoor, Tahereh Yazdani, Mohammad Alidoosti, Vahid Ghasem-Amooeian, Haleh Ashraf
Background: It has been implicated that obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular disease including stroke, myocardial infarction, coronary artery disease (CAD) and hypertension. The aim of this study was to investigate the correlation between OSA and severity of atherosclerosis assessed by angiography. Methods: This study included 337 patients undergoing diagnostic coronary angiography at Tehran Heart Center, Iran. The Gensini score was obtained from each patient for coronary angiogram, and OSA were assessed by using Multivariable apnea prediction (MAP) risk index on the day of cardiac catheterization...
2018: Caspian Journal of Internal Medicine
Samaneh Akbarpour, Davood Khalili, Hojjat Zeraati, Mohammad Ali Mansournia, Azra Ramezankhanim, Akbar Fotouhi
Background: The present study evaluated the lifestyle behavior patterns and its associations with demographic factors in the Iranian population. Methods: A total of 8244 people aged 25-70 years who participated in a national survey in 2011 were included in the study. Factors related to lifestyle (such as diet, physical activity, and tobacco use) have been collected using a questionnaire. A self-organizing map was used for cluster analysis and a multinomial logistic model was used for assessment of associations...
2018: Caspian Journal of Internal Medicine
Maryam Gholinezhad, Masoumeh Gholsorkhtabaramiri, Sedigheh Esmaeilzadeh, Azita Ghanbarpour
Background: Polycystic ovary syndrome (PCOs) is an endocrine-metabolic disorder. This study intends to determine the comparison of insulin resistance (IR) and metabolic disturbance in overweight/obese and normal-weight of young women with polycystic ovary syndrome. Methods: Using a comparative cross-sectional study design in 2015, 27 normal weight (18<BMI<25) and 85 overweight/obese (BMI≥25) aged 18 and 35 underwent clinical measures of HOMA (IR) as insulin resistance and QUICKI as insulin sensitivity tools in Fatemezahra Infertility Research Center of Babol...
2018: Caspian Journal of Internal Medicine
Afsaneh Bakhtiari, Karimollah Hajian-Tilaki, Azita Ghanbarpour
Background: Current literature has been focused on types of obesity with normal BMI (body mass index), but metabolically unhealthy.This study evaluates the prevalence of metabolical phenotypes of obesity. We also identified the best obesity index in predicting the components of metabolic syndrome (MetS). Methods: A cross-sectional s tudy has been conducted on 164 women over 60 years. Anthropometric parameters, body fat percentage (%BF), and biologic criteria were measured to assess the types of obesity...
2018: Caspian Journal of Internal Medicine
Shahnaz Shahrbanian, Pierre Duquette, Nancy E Mayo
Background: Identifying the predictors of pain is important for both health professionals and researchers, because pain has repeatedly been found to be a strong predictor of activity limitations and participation restrictions. The objective of this study was to determine the predictors of pain presence and severity in a large, well-designed sample of community dwelling individuals with multiple sclerosis (MS). Methods: This was a cross-sectional study. A center-stratified random sample including 188 persons with MS were recruited from three major MS clinics in the Greater Montreal, Canada...
2018: Caspian Journal of Internal Medicine
Ali-Akbar Hajiaghamohammadi, Mohammad-Mahdi Daee, Ali Zargar, Somayeh Ahmadi-Gooraji, Alfred Rahban, Fereshte Attaran
Background: Cirrhosis as the final stage of progressive fibrosis of liver can affect other organs such as lungs, kidneys and heart. "Cirrhotic cardiomyopathy" involves the electrophysiological abnormalities such as QT interval prolongation. We assessed correlation between corrected QT interval prolongation and severity of cirrhosis based on Child Classification in each ECG lead. Methods: In this case-control study, the patients attending the outpatient clinic and inpatient department of internal medicine of Velayat Hospital in Qazvin were enrolled from September 2014 to July 2015...
2018: Caspian Journal of Internal Medicine
Mansour Babaei, Ali Bijani, Parnaz Heidari, Seyyed Reza Hosseini, Behzad Heidari
Background: Iron overload influences negatively on bone mineral density (BMD) but the results of studies regarding serum ferritin (SF) and BMD are conflicting.This study aimed to determine the association of SF and BMD in the elderly. Methods: All participants of the Amirkola cohort selected between 2011-2012, aged > 60 years were classified as high or normal (<200ng/ml) SF. BMD at femoral neck and lumbar spine was determined by dual energy x-ray absorptiometry (DXA) and the results were expressed as BMD g/cm2 and BMDT-score...
2018: Caspian Journal of Internal Medicine
Fatih Uzer, Omer Ozbudak
Background: Asthma is one of the most common chronic diseases and may cause psychiatric disorders affecting the patients' quality of life. In our study, we evaluated the effect of omalizumab treatment on anxiety disorder and depression using Beck Depression Scale (BDS) and State Trait Anxiety Inventory (STAI). Methods: Anxiety level was determined with STAI, whereas depression level was evaluated by BDS. Patients were asked to mark the questionnaires to reflect their emotional state before treatment, and to reflect their emotions they are feeding in the current moment...
2018: Caspian Journal of Internal Medicine
Farzan Kheirkhah, Gooya Tayyebi, Seyed Mozaffar Rabiee, Ali-Akbar Moghadamnia, Ali Bijani
Background: Major depressive disorder is a severe, heterogeneous, common medical illness and a leading cause of disability throughout the world that poses a significant public health issue. Previous studies have shown rapid antidepressant effects following a single administration of ketamine. This study aimed to assess the impact of route of administration and dose of ketamine for the reduction of depressive symptoms and compare the effects of different doses and methods. Methods: A double-blind clinical controlled trial was done on 100 patients with a primary diagnosis of major depressive disorder who were assigned into two groups of 50 subjects at a dose of 0...
2018: Caspian Journal of Internal Medicine
Zahra Geraili, Seyed Mohammad Riahi, Soghra Khani, Ali Rostami, Masomeh Bayani, Karimollah Hajian-Tilaki, Malihe Nourollahpour Shiadeh
Background: Cytomegalovirus (CMV) infection is one of the most common infectious diseases in pregnant women in terms of global impact and is related with many adverse health consequences during pregnancy. For the first time, we performed a systematic review and meta-analysis study to evaluate the possible association between CMV infection and preeclampsia (PE). Methods: A comprehensive literature search to identify the relevant papers published earlier than February 2018 was performed in PubMed, ISI (Web of Science), Google Scholar and SCOPUS databases...
2018: Caspian Journal of Internal Medicine
Sahar Rostami, Mohammad-Sajad Emami-Aleagha, Maryam Ghasemi-Kasman, Abdolamir Allameh
Multiple sclerosis (MS) is an inflammatory demyelinating disease, which is considered as a common autoimmune disorder in young adults. A growing number of evidences indicated that the impairment in non-neural tissues plays a significant role in pathology of MS disease. There are bidirectional relationship, metabolic activities and functional similarity between central nervous system (CNS) and kidneys which suggest that kidney tissue may exert remarkable effects on some aspects of MS disorder and CNS impairment in these patients compels the kidney to respond to central inflammation...
2018: Caspian Journal of Internal Medicine
Saeid Komasi, Ali Soroush, Mozhgan Saeidi
No abstract text is available yet for this article.
2018: Caspian Journal of Internal Medicine
Kaveh Gharaei Nejad, Hojat Eftekhari, Rana Rafiei, Abbas Darjani, Narges Alizadeh
Background: Darier disease (DD) is an autosomal dominant genetic disorder which develops from a mutation in the ATP2A2 gene. Inflammatory myopathies (IM) are the largest group of potentially treatable myopathies. In this case, we report development of IM in a patient with DD for the second time in the literature. Case presentation: The patient is a 59-year-old female, a known case of DD, who developed proximal muscle weakness 2 weeks prior to admission. Elevated muscle-enzymes, as well as typical electromyographic and radiologic confirmed the diagnosis of IM...
2018: Caspian Journal of Internal Medicine
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