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International Journal of Endocrinology and Metabolism

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https://www.readbyqxmd.com/read/28144252/endocrinology-is-fascinating
#1
EDITORIAL
Fereidoun Azizi
No abstract text is available yet for this article.
October 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28144251/permanent-and-transient-congenital-hypothyroidism-in-hamadan-west-province-of-iran
#2
Zahra Razavi, Lida Mohammadi
BACKGROUND: Primary congenital hypothyroidism (CH) is the most common treatable cause of mental retardation and can be classified into permanent and transient types. The purpose of this study was to determine the prevalence of permanent and transient congenital hypothyroidism (CH) in Hamadan, West province of Iran. METHODS: The study population included all cases with primary congenital hypothyroidism, which were confirmed by thyroid function tests (TSH levels ≥ 10 mIU/L)...
October 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28123438/a-rare-and-severe-complication-following-thyroid-fine-needle-aspiration-retropharyngeal-cellulitis
#3
Roberto Cesareo, Anda Naciu, Antonio Barberi, Valerio Pasqualini, Giuseppe Pelle, Silvia Manfrini, Gaia Tabacco, Angelo Lauria Pantano, Giuseppe Campagna, Roberto Cianni, Andrea Palermo
INTRODUCTION: Fine needle aspiration (FNA) is the most accurate and cost-effective method for evaluating thyroid nodules. We have reported a rare complication related to the procedure: severe retropharyngeal cellulitis. CASE PRESENTATION: A thirty-five-year-old female was admitted to hospital with hoarseness, laryngeal stridor and dyspnea without fever that emerged about 3 days after a first diagnostic FNA. After the procedure, the patient felt her voice became hoarse and 1 day before presentation began to have dyspnea, without fever...
October 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28123437/a-case-series-congenital-hyperinsulinism
#4
Mohammad Reza Alaei, Susan Akbaroghli, Mohammad Keramatipour, Ali Alaei
INTRODUCTION: Congenital hyperinsulinism is a rare inherited disease caused by mutations in genes responsible for β-cell's function in glucose hemostasis leading to profound and recurrent hypoglycemia. The incidence of the disease is about 1 in 50000 newborns. Mutations in at least 8 genes have been reported to cause congenital hyperinsulinism. Mutations in ABCC8 gene are the most common cause of the disease that account for approximately 40% of cases. Less frequently KCNJ11 gene mutations are responsible for the disease...
October 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28123436/review-of-the-mechanisms-and-effects-of-noninvasive-body-contouring-devices-on-cellulite-and-subcutaneous-fat
#5
REVIEW
Zahra Alizadeh, Farzin Halabchi, Reza Mazaheri, Maryam Abolhasani, Mastaneh Tabesh
CONTEXT: Today, different kinds of non-invasive body contouring modalities, including cryolipolysis, radiofrequency (RF), low-level laser therapy (LLLT), and high-intensity focused ultrasound (HIFU) are available for reducing the volume of subcutaneous adipose tissue or cellulite. Each procedure has distinct mechanisms for stimulating apoptosis or necrosis adipose tissue. In addition to the mentioned techniques, some investigations are underway for analyzing the efficacy of other techniques such as whole body vibration (WBV) and extracorporeal shockwave therapy (ESWT)...
October 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28123435/transforming-growth-factor-%C3%AE-1-tgf-%C3%AE-1-in-the-sera-of-postmenopausal-osteoporotic-females
#6
Aazam Faraji, Shabnam Abtahi, Abbas Ghaderi, Alamtaj Samsami Dehaghani
BACKGROUND: Postmenopausal osteoporosis is a major cause of morbidity in postmenopausal females. Transforming growth factor β1 (TGF-β1) and interleukin 18 (IL-18) play complex roles in normal bone metabolism, and in pathophysiology of postmenopausal osteoporosis. OBJECTIVES: The aim of this study was to design an analytic cross sectional study in order to further clarify the role of TGF-β1 and IL-18 in osteoporosis of postmenopausal females. METHODS: A cross sectional study including 65 postmenopausal osteoporotic females as cases and 69 postmenopausal females of similar age without osteoporosis as controls was conducted...
October 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28123434/asymmetric-dimethylarginin-adma-as-a-marker-of-endothelial-dysfunction-in-primary-aldosteronism
#7
Joanna Matrozova, Vladimir Vasilev, Silvia Vandeva, Atanaska Elenkova, Georgi Kirilov, Sabina Zaharieva
BACKGROUND: Recent studies have revealed a higher rate of cardiovascular complications in primary aldosteronism (PA) compared to patients with essential hypertension (EH). Asymmetric dimethylarginine (ADMA) is a marker of endothelial dysfunction that could contribute to increased cardiovascular risk in patients with PA. OBJECTIVES: The aim of this study was to compare the levels of ADMA among patients with PA, controls with EH and healthy participants. Methods: Serum ADMA levels were determined, using commercially available competitive enzyme-linked immunosorbent assay...
October 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28115967/precision-medicine-for-endocrinology
#8
EDITORIAL
Fereidoun Azizi
No abstract text is available yet for this article.
July 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28115966/the-effect-of-walnut-oil-consumption-on-blood-sugar-in-patients-with-diabetes-mellitus-type-2
#9
Mohammadjavad Zibaeenezhad, Kamran Aghasadeghi, Hossein Hakimi, Hassan Yarmohammadi, Farzad Nikaein
BACKGROUND: Prevalence of diabetes mellitus type 2 (DM) is increasing globally. Considering the potential role of poly-unsaturated fatty acids in prevention of DM type 2 and lipid profiles improvement, some studies have been carried out on walnut. However, there are no studies on control of blood sugar in DM type 2 patients using walnut. OBJECTIVES: The current study aimed to evaluate the effect of walnut oil on blood sugar in DM type 2 patients. METHODS: This randomized control clinical trial was performed on 100 patients with DM type 2...
July 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27942265/correlations-between-changes-in-undercarboxylated-osteocalcin-and-muscle-function-in-hypoparathyroidism
#10
Torben Harslof, Tanja Sikjaer, Leif Mosekilde, Bente L Langdahl, Lars Rejnmark
BACKGROUND: Muscles and bones are interconnected. Recent studies suggest that undercarboxylated osteocalcin from bone may affect muscle mass and strength. There are, however, no prospective human data on this relationship. METHODS: We previously treated patients with hypoparathyroidism with intact Parathyroid Hormone (PTH) or placebo in a six-month randomized, placebo-controlled trial and demonstrated a marked increase in undercarboxylated osteocalcin (ucOC) in the PTH-treated group...
July 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27942264/the-relationship-between-increased-epicardial-fat-thickness-and-left-ventricular-hypertrophy-and-carotid-intima-media-thickness-in-patients-with-nonfunctional-adrenal-incidentaloma
#11
Nasiroglu Narin Imga, Ozgul Ucar Elalmis, Mazhar Muslum Tuna, Bercem Aycıcek Dogan, Deniz Sahin, Dilek Berker, Serdar Guler
BACKGROUND: Emerging evidences indicate that patients diagnosed with Adrenal Incidentaloma (AI) may present cardiovascular complications. Epicardial fat thickness (EFT) has recently been described as a new risk factor and an active player in metabolic syndrome and cardiovascular disease. OBJECTIVES: We aimed to evaluate the relationship between EFT and left ventricular hypertrophy and carotid intima-media thickness, which are both strong predictors of cardiovascular morbity and mortality, in patients with nonfunctioning AI...
July 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27942263/the-association-between-physical-activity-during-pregnancy-and-gestational-diabetes-mellitus-a-case-control-study
#12
Fatemeh Nasiri-Amiri, Afsaneh Bakhtiari, Mahbobeh Faramarzi, Hajar Adib Rad, Hajar Pasha
BACKGROUND: Gestational diabetes mellitus is one of the most common complications of pregnancy. Physical activity is associated with a lower risk of type 2 diabetes mellitus. A recent meta-analysis study suggested that more research is needed to investigate the type, duration and intensity of physical activity that can help to reduce the risk of gestational diabetes mellitus. OBJECTIVES: The present study aimed to understand the association between physical activity and gestational diabetes mellitus through comparing the type and intensity of physical activity performed by pregnant females with gestational diabetes and healthy pregnant females in the first 20 weeks of their pregnancy...
July 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27942262/association-between-obstructive-sleep-apnea-and-osteoporosis-a-systematic-review-and-meta-analysis
#13
REVIEW
Sikarin Upala, Anawin Sanguankeo, Soontharee Congrete
CONTEXT: Hypoxia reduces osteoblast growth resulting in bone thinning and osteoporosis. Although obstructive sleep apnea (OSA) with recurrent hypoxia might be a contributing factor for osteoporosis development, whether OSA is a risk or protective factor for osteoporosis has not been demonstrated. OBJECTIVES: This systematic review and meta-analysis evaluated the association between OSA and osteoporosis using published observational studies. DATA SOURCES: PubMed/MEDLINE and EMBASE databases...
July 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27942261/congenital-hypothyroidism-optimal-initial-dosage-and-time-of-initiation-of-treatment-a-systematic-review
#14
REVIEW
Khaled Rahmani, Shahin Yarahmadi, Koorosh Etemad, Ahmad Koosha, Yadollah Mehrabi, Nasrin Aghang, Hamid Soori
CONTEXT: Appropriate management of neonates, tested positive for congenital hypothyroidism (CH), in particular, the initial dosage of levothyroxine and the time of initiation of treatment is a critical issue. The aim of this study was to assess all current evidence available on the subject to ascertain the optimal initial dose and optimal initiation time of treatment for children with CH. EVIDENCE ACQUISITION: In this study, all published research related to the initiation treatment dose and the onset time of treatment in congenital hypothyroidism were reviewed...
July 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27942260/effect-of-infrared-radiation-on-the-healing-of-diabetic-foot-ulcer
#15
Ashrafalsadat Hakim, Ali Sadeghi Moghadam, Abdalali Shariati, Hamid Karimi, Mohamad Hossien Haghighizadeh
BACKGROUND: Diabetic foot ulcer is a worldwide health care concern affecting tens of thousands of patients. If these ulcers left untreated, they can create severe complications. OBJECTIVES: This study was designed to examine the effect of infrared radiation on the healing of diabetic foot ulcer. PATIENTS AND METHODS: This clinical trial was performed on 50 patients referred to Dr. Ganjavian hospital in Dezful city, Iran, with diabetic foot ulcer degree 1 and 2 (based on Wegener Scale)...
July 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28058053/survival-regression-modeling-strategies-in-cvd-prediction
#16
Mahnaz Barkhordari, Mojgan Padyab, Mahsa Sardarinia, Farzad Hadaegh, Fereidoun Azizi, Mohammadreza Bozorgmanesh
BACKGROUND: A fundamental part of prevention is prediction. Potential predictors are the sine qua non of prediction models. However, whether incorporating novel predictors to prediction models could be directly translated to added predictive value remains an area of dispute. The difference between the predictive power of a predictive model with (enhanced model) and without (baseline model) a certain predictor is generally regarded as an indicator of the predictive value added by that predictor...
April 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27761144/obesity-paradox-and-recurrent-coronary-heart-disease-in-a-population-based-study-tehran-lipid-and-glucose-study
#17
Samaneh Asgari, Maryam Barzin, Farhad Hosseinpanah, Farzad Hadaegh, Fereidoun Azizi, Davood Khalili
BACKGROUND: Although current data shows a positive association between obesity and development of coronary heart disease (CHD) in general population, there is limited data on the important protective role of central or general obesity in patients with prevalent CHD or the "obesity paradox", from this region. OBJECTIVES: The objective of the present investigation was to describe the relationship between BMI categories and the recurrence of CHD in patients with a history of CHD using data from a large population-based study, the Tehran lipid and glucose study (TLGS)...
April 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27761143/altered-concentrations-of-copper-zinc-and-iron-are-associated-with-increased-levels-of-glycated-hemoglobin-in-patients-with-type-2-diabetes-mellitus-and-their-first-degree-relatives
#18
Somayeh Atari-Hajipirloo, Neda Valizadeh, Mohammad-Hassan Khadem-Ansari, Yousef Rasmi, Fatemeh Kheradmand
BACKGROUND: The altered levels of some essential trace elements and antioxidant minerals have been observed in diabetic patients. OBJECTIVES: The aim of the present study was to compare the concentrations of essential trace elements, copper (Cu), zinc (Zn), and iron (Fe) in the serum of patients who have type 2 diabetes mellitus (T2DM) with those of their non-diabetic first-degree relatives (FDR) and control subjects. The association between glycated hemoglobin (HbA1c) and levels of metals was also evaluated...
April 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27679652/care-of-the-athlete-with-type-1-diabetes-mellitus-a-clinical-review
#19
REVIEW
William B Horton, Jose S Subauste
CONTEXT: Type 1 diabetes mellitus (T1DM) results from a highly specific immune-mediated destruction of pancreatic β cells, resulting in chronic hyperglycemia. For many years, one of the mainstays of therapy for patients with T1DM has been exercise balanced with appropriate medications and medical nutrition. Compared to healthy peers, athletes with T1DM experience nearly all the same health-related benefits from exercise. Despite these benefits, effective management of the T1DM athlete is a constant challenge due to various concerns such as the increased risk of hypoglycemia...
April 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27679651/recurrence-of-hyperparathyroid-hypercalcemia-in-a-patient-with-the-hrpt-2-mutation-and-a-previous-parathyroid-carcinoma-in-hyperparathyroidism-jaw-tumor-syndrome
#20
Marco Mele, Lars Rolighed, MarieLouise Jespersen, Lars Rejnmark, Peer Christiansen
INTRODUCTION: Cancer in the parathyroid gland is rare, but parathyroid cancer is occasionally seen in relation to genetic abnormalities. Due to a limited amount of evidence, the optimal handling of these cases is not clear. Furthermore, the presence of a malignant parathyroid tumor is rarely known at the time of the initial operation; therefore, re-operations are often necessary. The aim of this study was to present the case of a patient with a previously diagnosed jaw tumor and parathyroid carcinoma that presents as a recurrence of hyperparathyroid hypercalcemia...
April 2016: International Journal of Endocrinology and Metabolism
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