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Contemporary Oncology Współczesna Onkologia

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https://www.readbyqxmd.com/read/28947891/co-existence-of-mucin-producing-urothelial-type-adenocarcinoma-of-the-prostate-and-inverted-papilloma-of-the-bladder
#1
Xiao-Nan Mu, Si-Jun Wang, Zhi-Gang Sun, Min Zhang, Zhe Li, Long-Yang Zhang
Adenocarcinoma of prostate with mucinous differentiation arising in the male urethra is extremely rare, with only 21 cases reported in the previous literature. A diagnosis of mucin-producing urothelial carcinoma of the prostate is based on the pathology, immunohistochemistry, and clinical examination by excluding the secondary adenocarcinoma of the prostate. We present a case of unexpected mucinous urothelial carcinoma of prostate with co-existing inverted papilloma of bladder in a 57-year-old man. The patient underwent transurethral resection of the prostate (TURP) and transurethral resection of a bladder tumour (TUR-Bt), and the pathologic result showed mucinous prostate carcinoma and bladder inverted papilloma...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947890/the-prevalence-of-squamous-cell-carcinoma-in-different-sites-of-oral-cavity-at-our-rural-health-care-centre-in-loni-maharashtra-a-retrospective-10-year-study
#2
Parul Tandon, Anuj Dadhich, Harish Saluja, Shilpa Bawane, Shivani Sachdeva
AIM OF THE STUDY: Oral cancer ranks in the top three of all cancers in India and is quickly becoming a global health priority. More than 90% of oral and oropharyngeal cancers are squamous cell carcinoma. The purpose of this study was to document its incidence depending upon the involvement of different sites of oral cavity, and its variation with age and gender. MATERIAL AND METHODS: Histopathologically proven oral squamous cell carcinoma cases were collected from the department of oral and maxillofacial surgery RDC, PIMS...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947889/laparoscopic-distal-resection-of-the-pancreas-can-be-all-resections-of-body-and-tail-of-the-pancreas-called-the-same
#3
Audrius Šileikis, Augustas Beiša, Virgilijus Beiša, Mindaugas Kvietkauskas, Marius Kryžauskas, Kęstutis Strupas
INTRODUCTION: Distal resection of the pancreas is a routine procedure in high-volume centres. However, the volume of this procedure can vary. This variation plays a very important role in laparoscopic approach of pancreatic surgery and can be a real challenge if the anatomical situation is underestimated. AIM OF THE STUDY: To present our experience in minimally invasive treatment of the pancreatic tumours and to discuss different approaches to different anatomical situations...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947888/ct-mri-accuracy-in-detecting-and-determining-preoperative-stage-of-gastric-adenocarcinoma-in-albania
#4
Altin Malaj, Fatmir Bilaj, Albana Shahini, Marjeta Miraka
AIM OF THE STUDY: Gastric adenocarcinoma is among most frequent among cancers in Albania. Early detection and staging is helped by imaging methods, including CT and MRI. This study provides evidence on the CT and MRI accuracy in detecting and pre-operative staging of gastric adenocarcinoma in 62 patients in a diagnostic clinic in Albania. The correct staging of the gastric adenocarcinoma helps decide on the next treatment options. MATERIAL AND METHODS: Sixty-two patients with gastric adenocarcinoma, confirmed with biopsy, underwent both CT and MRI examination at a clinic in Tirana during same week...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947887/link-between-diet-and-chemotherapy-related-gastrointestinal-side-effects
#5
Marcin Mardas, Radosław Madry, Marta Stelmach-Mardas
AIM OF THE STUDY: To evaluate an association between food products consumption, dietary intake and the incidence of selected gastrointestinal symptoms (nausea, vomiting, diarrhea and constipation) in cancer patients undergoing chemotherapy. MATERIAL AND METHODS: Fifty six women receiving chemotherapy for ovarian cancer were eligible for the study. Anthropometrical measurements were assessed. The dietary intake was evaluated by 24-hours food records. The association between the consumption of selected food products and gastrointestinal symptoms incidences was assessed by modified semi-quantitative food frequency questionnaire including 77-different food items that was developed and applied in cancer patients undergoing chemotherapy...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947886/nutritional-status-assessment-in-colorectal-cancer-patients-qualified-to-systemic-treatment
#6
Monika Ziętarska, Joanna Krawczyk-Lipiec, Leszek Kraj, Renata Zaucha, Sylwia Małgorzewicz
AIM OF THE STUDY: Cancer is usually associated with impaired nutritional status, which is one of the factors contributing to the deterioration of the results of surgery, chemotherapy, or radiotherapy. The aim of this study was the assessment of the nutritional status of patients with CRC qualified to chemotherapy. MATERIAL AND METHODS: Seventy-five persons aged 40-86 years with colorectal cancer were examined. To evaluate the nutritional status NRS 2002, SGA, SCRINIO Working Group classification, VAS scale for appetite, and FAACT questionnaire were used...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947885/the-safety-of-low-molecular-weight-heparins-in-the-prevention-of-venous-thromboembolism-in-surgically-treated-cancer-patients-results-of-a-multicentre-observational-study
#7
Tomasz Olesiński, Anna Fijałkowska, Andrzej Rutkowski
AIM OF THE STUDY: Despite widespread use of pharmacological prophylaxis, venous thromboembolism (VTE) still constitutes a common complication in cancer patients. The aim of the study was to analyse the safety of low-molecular-weight heparins (LMWH) in the prevention of VTE in surgically-treated cancer patients. MATERIAL AND METHODS: A total of 5207 cancer patients (44.5% men and 55.5% women) aged 16-97 years participated in a prospective observational study conducted in 13 Polish cancer centres in 2005-2008...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947884/expression-of-vitamin-d-receptor-and-vitamin-d-status-in-patients-with-oral-neoplasms-and-effect-of-vitamin-d-supplementation-on-quality-of-life-in-advanced-cancer-treatment
#8
Akshay Anand, Suyash Singh, Abhinav A Sonkar, Nuzhat Husain, Kul Ranjan Singh, Sudhir Singh, Jitendra K Kushwaha
AIM OF THE STUDY: Vitamin D receptor (VDR) expression and serum vitamin D scores in oral premalignant lesions and oral cancer have not been widely analyzed. The role of vitamin D supplementation in advanced oral cancer for improving quality of life (QOL) is also a matter of research. MATERIAL AND METHODS: Vitamin D receptor expression and vitamin D scores were analyzed in normal oral mucosa (n = 95), leukoplakia (n = 23) and oral cancer (n = 87). 45 patients with advanced oral cancer subjected to chemoradiation were evaluated for the effect of vitamin D supplementation on most observable QOL parameters such as oral mucositis, swallowing performance and overall QOL...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947883/network-analysis-based-on-tcga-reveals-hub-genes-in-colon-cancer
#9
Fenzan Wu, Guoping Yuan, Junjie Chen, Chengzu Wang
Colorectal cancer (CRC) is the third most widespread cancer in the world. Although many advances have been made in molecular biology, novel approaches are still required to reveal molecular mechanisms for the diagnosis and therapy of colon cancer. In this study, we aimed to determine and analyse the hub genes of CRC. First, we explored the mRNA and microRNA (miRNA) expression profiles of colon carcinoma, then we screened target genes of differentially expressed miRNAs and obtained the intersection between differently expressed genes and target genes...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947882/the-problem-of-fatigue-in-patients-suffering-from-neoplastic-disease
#10
REVIEW
Agnieszka Kolak, Marzena Kamińska, Elwira Wysokińska, Dariusz Surdyka, Dariusz Kieszko, Magdalena Pakieła, Franciszek Burdan
Modern therapeutic management of patients with cancer is associated with many adverse side effects, including fatigue defined as weariness, burnout, lassitude, malaise, apathy, impatience, and/or inability to perform daily activities. It occurs frequently before the diagnosis of cancer and may persist for a long time after the end of cancer therapy. It is a common problem that occurs regardless of the type of cancer and applied therapeutic procedure. The appearance of this symptom significantly affects the quality of life of patients and often reduces the effectiveness of implemented treatment...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947881/post-glossectomy-in-lingual-carcinomas-a-scope-for-sign-language-in-rehabilitation
#11
REVIEW
Arvind Babu Rajendra Santosh, Keren Cumberbatch, Thaon Jones
The treatment option for cancers of the tongue is glossectomy, which may be partial, sub-total, or total, depending on the size of the tumour. Glossectomies result in speech deficits for these patients, and rehabilitative therapy involving communication modalities is highly recommended. Sign language is a possible therapeutic solution for post-glossectomy oral cancer patients. Patients with tongue cancers who have undergone total glossectomy as a surgical treatment can utilise sign language to replace their loss of speech production and maintain their engagement in life...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947880/current-treatment-options-for-gastroenteropancreatic-neuroendocrine-tumors-with-a-focus-on-the-role-of-lanreotide
#12
REVIEW
Beata Kos-Kudła, Jarosław Ćwikła, Marek Ruchała, Alicja Hubalewska-Dydejczyk, Barbara Jarzab, Jolanta Krajewska, Grzegorz Kamiński
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a large and very diverse group of neoplasms. Clinical presentation of NETs depends on the site of the primary tumor and whether the tumor is functioning (i.e., secreting peptides or neuroamines that produce symptoms). The diagnosis of GEP-NET is further complicated by symptomatic differences that occur depending on the type of secreted peptide or neuroamine. Due to their heterogeneity and unique characteristics, early diagnosis of GEP-NETs is difficult, which increases the likelihood of metastatic disease and reduces the scope of therapeutic possibilities...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947879/the-role-of-fdg-pet-in-hodgkin-lymphoma
#13
REVIEW
Edyta Subocz, Janusz Hałka, Mirosław Dziuk
18-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) is currently the most valuable imaging technique in Hodgkin lymphoma. Since its first use in lymphomas in the 1990s, it has become the gold standard in the staging and end-of-treatment remission assessment in patients with Hodgkin lymphoma. The possibility of using early (interim) PET during first-line therapy to evaluate chemosensitivity and thus personalize treatment at this stage holds great promise, and much attention is now being directed toward this goal...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947878/diagnostic-methods-for-detection-of-bone-metastases
#14
REVIEW
Bartosz Łukaszewski, Jerzy Nazar, Maciej Goch, Marta Łukaszewska, Adrian Stępiński, Mieczysława U Jurczyk
Skeletal metastases are severe complications in the course of cancer, and they indicate a worse prognosis. The use of modern imaging techniques allows rapid diagnosis of bone metastases. Properly selected diagnostic imaging (scintigraphy, positron emission tomography, whole body MRI) allows us to evaluate the number of metastatic foci in the skeletal system. Complementary imaging examinations (X-ray, computed tomography, magnetic resonance imaging) determine the extent of metastasis and its character: osteolytic, osteoblast, mixed)...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28947877/crosstalk-between-mesenchymal-stem-cells-and-macrophages-in-inflammatory-bowel-disease-and-associated-colorectal-cancer
#15
Fei Mao, Jing-Jing Kang, Xiu Cai, Ning-Feng Ding, Yun-Bing Wu, Yong-Min Yan, Hui Qian, Xu Zhang, Wen-Rong Xu
Mesenchymal stem cells (MSCs) are attractive seed cells for immunotherapy, tissue engineering and regenerative medicine due to their self-renewal and multidirectional differentiation abilities, diverse immunoregulatory functions and ease of isolation from a wide range of tissues. MSCs exert their immunoregulatory effect on immune cells via cell-to-cell contact and paracrine mechanisms. In turn, MSCs can also be modulated by immune cells. Macrophages are constantly present in the mucosa of the intestinal tract of mammals and play an important role in the development and progression of inflammatory bowel disease (IBD), a chronic and recurrent inflammatory disease of the gastrointestinal tract characterized by idiopathic mucosal inflammation...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28435404/phase-ii-study-of-adjuvant-docetaxel-and-carboplatin-with-without-doxorubicin-and-cyclophosphamide-in-triple-negative-breast-cancer-a-randomised-controlled-clinical-trial
#16
Safa Najafi, Mehrdad Payandeh, Masoud Sadeghi, Vahideh Shafaei, Fateme Shojaiyan, Fereshte Abbasvandi
AIM OF THE STUDY: The aim of this trial was to compare overall survival (OS), disease-free survival (DFS), and toxicity of two adjuvant regimens in triple negative patients with Iranian ethnicity. MATERIAL AND METHODS: In a phase II trial, patients with previously untreated triple negative breaststroke cancer were randomly assigned by using docetaxel 70 mg/m(2) and carboplatin AUC = 7 every three weeks with granulocyte colony-stimulating factor for sin courses (arm A) or doxorubicin hydrochloride 60 mg/m(2) and cyclophosphamide 600 mg/m(2) every three weeks with G-CSF for four courses followed by docetaxel 70 mg/m(2) and carboplatin AUC = 7 every three weeks with G-CSF for four courses (arm B)...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28435403/comparative-analysis-of-the-incidence-of-head-and-neck-cancer-in-south-eastern-poland-and-in-poland-in-the-years-1990-2012
#17
Jan Gawełko, Marek Cierpiał-Wolan, Andrzej Kawecki, Konrad Wilk, Danuta B Pięciak-Kotlarz, Damian Sikorski
AIM OF THE STUDY: To present the changes in the incidence of cancers of the head and neck organs in south-eastern Poland and in the whole country in the years 1990-2012. MATERIAL AND METHODS: A retrospective analysis the incidence of cancers of the head and neck organs in south-eastern Poland in the years 1990-2012. Statistical methods used for cancers of ICD-10 C00-C14 and C30-C32. RESULTS: For Poland, the absolute number of cases was 123,120 in the years 1990-2012...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28435402/synchronous-bilateral-testis-cancer-clinical-and-oncological-management
#18
Davide Campobasso, Stefania Ferretti, Antonio Frattini
Synchronous bilateral testis cancer (SBTC) is a rare event. It represents only 0.5-1% of all new cases of testicular cancer. Patients with this disease require careful management for psychological, oncological, and medical problems. We performed a PubMed search for all series that reported SBTC. We considered only articles in English, reporting on more than three cases. We also performed an analysis of the reported evidence regarding testosterone replacement and surgical treatment. We found 10 studies satisfying inclusion criteria for a total of 73 patients...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28435401/head-and-neck-lymphomas-a-retrospective-ten-year-observation
#19
Marcelina Niemiec, Grażyna Stryjewska-Makuch, Małgorzata Janik, Bogdan Kolebacz, Grażyna Lisowska, Wojciech Ścierski
AIM OF THE STUDY: Lymphomas are a heterogeneous group of tumours of lymphoid tissue in which there is an abnormal proliferation of cells of the lymphatic system. The literature notes a gradual increase in the incidence of this type of cancer in the whole population. The aim of the study was to evaluate whether the above tendency occurs in the head and neck area. MATERIAL AND METHODS: In the years 2005-2014, at the Otolaryngology and Laryngological Oncology Department of the Upper Silesian Medical Centre in Katowice, 77 cases of lymphoma were recorded, 58 of which were analysed in terms of location, histological type, age and sex of the patient, and the presence of risk factors...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/28435400/neoadjuvant-sequential-chemoradiotherapy-versus-radiotherapy-alone-for-treatment-of-high-risk-extremity-soft-tissue-sarcoma-a-single-institution-experience
#20
Leyla Kılıç, Meltem Ekenel, Senem Karabulut, Fulya Ağaoğlu, Emin Darendeliler
AIM OF THE STUDY: Patients with large and high-grade extremity soft-tissue sarcoma are at significant risk for distant metastasis and sarcoma-related death. There is no randomized trial comparing chemoradiotherapy to radiotherapy in the neoadjuvant setting for high risk extremity soft-tissue sarcoma. The aim of this study is to evaluate the outcomes of patients treated with two different modalities (neoadjuvant sequential chemoradiotherapy vs. radiotherapy alone) in a single center. MATERIAL AND METHODS: Data of 67 patients were analyzed retrospectively...
2017: Contemporary Oncology Współczesna Onkologia
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