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Rhode Island Medical Journal

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https://www.readbyqxmd.com/read/27903003/surveillance-of-suicide-and-suicide-attempts-among-rhode-island-youth-using-multiple-data-sources
#1
Yongwen Jiang, Deborah N Pearlman, Jeffrey Hill, Samara Viner-Brown
No abstract text is available yet for this article.
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27903002/ten-years-and-growing-medical-marijuana-in-rhode-island-where-are-we-now
#2
James V McDonald, Mike Simoli
No abstract text is available yet for this article.
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27903001/right-in-front-of-our-eyes-evolution-of-streptococcal-toxic-shock-syndrome-with-ischemic-optic-neuropathy
#3
Salaheldin M Elhamamsy, Mazen O Al-Qadi, Taro Minami, Marguerite Neill
INTRODUCTION: Toxic shock syndrome occurs from dysregulation of host inflammatory responses. Toxin- producing strains of Group A streptococcus cause TSS. Ischemic optic neuropathy rarely complicates septic shock. We present a rare case of streptococcal pharyngitis complicated by septic arthritis and TSS with reversible blindness due to non-arteritic ischemic optic neuropathy. CASE: A 28-year-old man drove to our ED with exudative pharyngitis. A rapid streptococcal test was positive...
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27903000/fournier-s-gangrene-of-the-penis-in-a-12-year-old-patient-secondary-to-phimosis
#4
Luther Ward, Daniel Eisenson, Jean-Louis Fils
We report a case of Fournier's gangrene in a 12-year-old boy from St. Boniface Hospital in Fond-des-Blancs, Haiti. Fournier's gangrene, a fulminant necrotizing fasciitis of the penis and scrotum, is a rare and life-threatening infection that requires hospitalization, broad-spectrum antibiotics, and surgical debridement.1-3 It is usually associated with impaired cellular immunity due to systemic disorders such as diabetes and liver disease.4,5 This patient had none of those risk factors, but had severe, longstanding phimosis, for which circumcision had been recommended many years before...
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27902999/fibromyalgia-syndrome-a-geriatric-challenge
#5
Julio C Defillo-Draiby, John S Page
No abstract text is available yet for this article.
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27902998/autoimmune-cytopenias-diagnosis-management
#6
Christian P Nixon, Joseph D Sweeney
The autoimmune cytopenias are a related group of disorders in which differentiated hematopoietic cells are destroyed by the immune system. Single lineage disease is characterized by the production of autoantibodies against red cells (autoimmune hemolytic anemia [AIHA]), platelets (autoimmune thrombocytopenia [ITP]) and neutrophils (autoimmune neutropenia [AIN]) whereas multilineage disease may include various combinations of these conditions. Central to the genesis of this disease is the breakdown of central and/or peripheral tolerance, and the subsequent production of autoantibodies by both tissue and circulating self-reactive B lymphocytes with support from T helper lymphocytes...
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27902997/chronic-inflammatory-demyelinating-polyradiculoneuropathy-cidp-clinical-features-diagnosis-and-current-treatment-strategies
#7
Jacques Reynolds, George Sachs, Kara Stavros
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an acquired immune-mediated disorder characterized by weakness and sensory deficits that can lead to significant neurological disability. The diagnosis is based on a combination of clinical examination findings, electrodiagnostic studies, and other supportive evidence. Recognizing CIDP and distinguishing it from other chronic polyneuropathies is important because many patients with CIDP are highly responsive to treatment with immunosuppressive or immunomodulatory therapies...
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27902996/pemphigus-pathogenesis-to-treatment
#8
Christopher DiMarco
Pemphigus vulgaris (PV), pemphigus foliaceus (PF), and paraneoplastic pemphigus (PNP) are a group of rare and fatal blistering diseases involving autoantibodies that target desmosomal proteins. The pathogenesis of pemphigus involves the production of activated B-cells and IgG with stimulation by IL-4 by T-helper 2 cells. Clinically these diseases present most often with epidermal erosions of the mucosae and skin caused by rapid rupturing of flaccid bullae. These lesions correlate histologically with splits forming in the epidermis, leaving a blister roof composed of a few cell layers...
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27902995/systemic-lupus-erythematosus-a-review-of-the-clinical-approach-to-diagnosis-and-update-on-current-targeted-therapies
#9
Joanne Szczygiel Cunha, Katarzyna Gilek-Seibert
Systemic lupus erythematosus (SLE) is a chronic, complicated and challenging disease to diagnose and treat. The etiology of SLE is unknown, but certain risk factors have been identified that lead to immune system dysfunction with antibody formation and immune complex deposition. This immune system dysregulation causes organ injury, contributing to the variable manifestations and relapsing-remitting course of the disease. Criteria were created to aide in the diagnosis, focusing on clinical manifestations and antibody profiles specific to SLE...
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27902994/targeted-immunomodulatory-therapy-an-overview
#10
Ashley L Lefebvre, Laura McAuliffe
Monoclonal antibodies and other biologic response modifiers have allowed for targeted drug therapy in managing various autoimmune diseases. A number of immune pathways have been exploited in the development of targeted immunomodulatory therapies, including cytokine-directed therapies such as tumor necrosis factor-alpha and interleukins, integrins, B-cells, and co-stimulation modulators. With new targeted therapies in the pipeline, more options are becoming available for treatment of autoimmune diseases. [Full article available at http://rimed...
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27902993/newer-treatment-strategies-for-autoimmune-diseases
#11
Edward V Lally
No abstract text is available yet for this article.
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27902992/reconnecting-with-my-purpose-in-the-kingdom-of-bhutan
#12
Eric Cohen
No abstract text is available yet for this article.
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27902991/dickensian-diagnostics-the-diseases-of-christmas-past-what-ailed-scrooge-and-tiny-tim
#13
Herbert Rakatansky
No abstract text is available yet for this article.
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27902990/medical-tourism
#14
Joseph H Friedman
No abstract text is available yet for this article.
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27801923/health-equity-implications-of-past-year-quit-attempts-among-current-adult-smokers-rhode-island-2011-2015
#15
Elsa Larson, Dana McCants Derisier
No abstract text is available yet for this article.
November 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27801922/introducing-rhode-island-s-health-equity-zones
#16
Mia Patriarca, Christopher J Ausura
Many social and environmental factors contribute to the health - and unhealthiness - of a community, and the mix of these factors varies widely from one community to another. A persistent challenge to public health is just how to address so many variables, in so many combinations, in so many diverse communities. The Rhode Island Department of Health is exploring an innovative approach, its Health Equity Zone Initiative, to meet this challenge. [Full article available at http://rimed.org/rimedicaljournal-2016-11...
November 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27801921/a-case-of-ileus-and-st-segment-elevation
#17
Osama Siddique, Somwail Rasla, Seth Clark, Aravind Kokkirala
ST segment elevation is associated with non-cardiac pathologies but is not as well reported as myocardial infarction. We present a case of a 63-year-old man who was admitted for an overdose on cyclobenzaprine with signs of anti-cholinergic toxicity. He developed signs of ileus on imaging and became progressively obtunded. He was noted to have ST segment elevations on electrocardiogram (EKG) with no troponin elevation. Patient required urgent catheterization which showed normal coronary arteries. His bowel was decompressed subsequently resulting in resolution of the ST segment changes...
November 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27801920/hydralazine-induced-anca-vasculitis-in-the-setting-of-acute-clostridium-difficile-infection
#18
Somwail Rasla, Amr El Meligy, Dragos F Cucu
We report a rare case of Hydralazine-induced ANCA associated glomerulonephritis with alveolar hemorrhage in the setting of acute Clostridium Difficile Infection. A 71-year-old Caucasian woman with hypertension, who was being treated with hydralazine 25 mg twice a day for six years, presented to the hospital with diarrhea, nausea, vomiting and anemia. She had acute kidney injury and urinalysis showed proteinuria, dysmorphic RBCs, and rare RBC cast. She was found to have Clostridium difficile colitis which was successfully treated...
November 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27801919/the-role-of-the-state-health-laboratories-in-advancing-health-equity
#19
Ewa King, Cynthia Vanner, Henry Leibovitz, Robin Smith
While laboratories play an important and recognized role in many public health programs that require surveillance of disease spread or monitoring of environmental conditions, the role of public laboratories in assessing and advancing health equity is not well understood. Yet, public laboratories collect, provide or generate much of the data used to determine health equity status and monitor heath equity trends in multiple settings and disciplines. RI State Health Laboratories, a division of the RI Department of Health, operates programs that help measure and address health disparities...
November 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27801918/diabetes-and-bmi-health-equity-through-early-intervention-on-dysglycemia-and-how-providers-can-help
#20
Dora M Dumont, Lanette Baker, Elise George, Nancy Sutton
Like most states in the U.S., Rhode Island's rate of type 2 Diabetes Mellitus (DM) is rising as its population has both aged and become heavier. Risk of both BMI>=30 and DM has risen across almost all demographics, but disparities continue to exist in both conditions. We analyzed state health survey data to assess race/ethnicity-stratified DM and BMI and the age-adjusted rate of DM by weight status relative to the late 1990s. The prevalence of obesity increased across almost all demographic groups relative to 15 years ago, but the rise was greatest among non-Hispanic whites...
November 1, 2016: Rhode Island Medical Journal
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