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Blood Research

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https://www.readbyqxmd.com/read/28401110/the-first-case-report-of-a-patient-with-coexisting-hemophilia-b-and-down-syndrome
#1
Pulkit Rastogi, Narender Kumar, Jasmina Ahluwalia, Reena Das, Inusha Panigrahi
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401109/a-rare-case-of-erythrophagocytosis-by-neutrophils-on-the-peripheral-blood-smear
#2
Jong Ho Lee
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401108/a-case-of-lymphocytic-variant-hypereosinophilic-syndrome-with-sub-diagnostic-systemic-mastocytosis
#3
Preetesh Jain, Sa A Wang, C Cameron Yin, Yasmin Abaza, Srdan Verstovsek, Zeev Estrov
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401107/is-n-acetylcysteine-infusion-an-effective-treatment-option-in-l-asparaginase-associated-hepatotoxicity
#4
Zeynep Canan Özdemir, Ayşe Bozkurt Turhan, Makbule Eren, Özcan Bor
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401106/jak2-exon-12-mutation-positive-myeloproliferative-neoplasm-associated-with-recurrent-thromboembolism
#5
Vahid Tavakoli, Sundee Naing
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401105/hypercalcemia-multiple-osteolytic-lesions-and-acute-renal-failure-a-rare-presentation-of-b-cell-acute-lymphoblastic-leukemia
#6
Vandana Puri, Pooja Sharma, Sundaram Gopalakrishnan, Meera Sikka, Rajnish Avasthi
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401104/therapy-related-acute-promyelocytic-leukemia-in-plasma-cell-myeloma-treated-with-melphalan-a-case-report-and-literature-review
#7
Hyunjung Gu, Young Jin Kim, Woo-In Lee, Juhee Lee, Hwi-Joong Yoon, Tae Sung Park
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401103/characterization-of-clonal-immunoglobulin-heavy-igh-v-d-j-gene-rearrangements-and-the-complementarity-determining-region-in-south-indian-patients-with-precursor-b-cell-acute-lymphoblastic-leukemia
#8
Natarajan Sudhakar, Thangarajan Rajkumar, Kamalalayam Raghavan Rajalekshmy, Nirmala Karunakaran Nancy
BACKGROUND: This study characterized clonal IG heavy V-D-J (IGH) gene rearrangements in South Indian patients with precursor B-cell acute lymphoblastic leukemia (precursor B-ALL) and identified age-related predominance in VDJ rearrangements. METHODS: IGH rearrangements were studied in 50 precursor B-ALL cases (common ALL=37, pre-B ALL=10, pro-B ALL=3) by polymerase chain reaction (PCR) heteroduplex analysis. Twenty randomly selected clonal IGH rearrangement sequences were analyzed using the IMGT/V-QUEST tool...
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401102/human-parvovirus-b19-in-patients-with-beta-thalassemia-major-from-tehran-iran
#9
Seyed Ali Mohammad Arabzadeh, Farideh Alizadeh, Ahmad Tavakoli, Hamidreza Mollaei, Farah Bokharaei-Salim, Gharib Karimi, Mohammad Farahmand, Helya Sadat Mortazavi, Seyed Hamidreza Monavari
BACKGROUND: Due to the tropism of human parvovirus B19 to erythroid progenitor cells, infection in patients with an underlying hemolytic disorder such as beta-thalassemia major leads to suppression of erythrocyte formation, referred to as transient aplasia crisis (TAC), which may be life-threatening. We investigated the prevalence of parvovirus B19 among patients with beta thalassemia major attending the Zafar Adult Thalassemia Clinic in Tehran, Iran. METHODS: This cross-sectional study was performed to determine the presence of parvovirus B19 DNA in blood samples and parvovirus B19 genotypes in plasma samples of patients with thalassemia major...
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401101/warm-autoimmune-hemolytic-anemia-experience-from-a-single-referral-center-in-mexico-city
#10
Hernandez-Company Alonso, Anguiano-Alvarez Victor Manuel, Carmona Gonzalez Carlos Amir, Rodriguez-Rodriguez Sergio, Pomerantz Allan, Lopez-Karpovitch Xavier, Tuna-Aguilar Elena Juventina
BACKGROUND: Autoimmune hemolytic anemia (AIHA) is characterized by an autoimmune-mediated destruction of red blood cells. Warm AIHA (wAIHA) represents 60% of AIHA cases and is associated with the positive detection of IgG and C3d in the direct antiglobulin test (DAT). This study aimed to assess the clinical and laboratorial differences between primary and secondary wAIHA patients from a referral center in Mexico City. METHODS: All patients diagnosed with wAIHA in our institution from January 1992 to December 2015 were included and received corticosteroids as the first-line treatment...
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401100/generation-of-hematopoietic-stem-cells-from-human-embryonic-stem-cells-using-a-defined-stepwise-serum-free-and-serum-replacement-free-monolayer-culture-method
#11
So-Jung Kim, Ji-Won Jung, Hye-Yeong Ha, Soo Kyung Koo, Eung-Gook Kim, Jung-Hyun Kim
BACKGROUND: Embryonic stem cells (ESCs) can be expanded infinitely in vitro and have the potential to differentiate into hematopoietic stem cells (HSCs); thus, they are considered a useful source of cells for HSC production. Although several technical in vitro methods for engineering HSCs from pluripotent stem cells have been developed, clinical application of HSCs engineered from pluripotent stem cells is restricted because of the possibility of xenogeneic contamination resulting from the use of murine materials...
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401099/physicians-preferences-and-perceptions-regarding-donor-selection-in-allogeneic-stem-cell-transplantation-in-korea-when-a-matched-domestic-donor-is-not-available
#12
Min Kyung Shin, Sangjin Shin, Ja Youn Lee, Youngil Koh
BACKGROUND: A number of alternative donor options exist for patients who fail to find domestic HLA-matched donors for allogeneic hematopoietic stem cell transplantation (allo-HSCT). We assessed physicians' perspectives on allo-HSCT donor selection when a matched domestic donor is not available. METHODS: We administered a questionnaire survey to 55 hematologists (response rate: 28%) who attended the annual spring conference of the Korean Society of Haematology in 2015...
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401098/elevated-expression-of-dnmt1-is-associated-with-increased-expansion-and-proliferation-of-hematopoietic-stem-cells-co-cultured-with-human-mscs
#13
Moharram Ahmadnejad, Naser Amirizadeh, Roya Mehrasa, Ahmad Karkhah, Mahin Nikougoftar, Arezoo Oodi
BACKGROUND: Mesenchymal stem cells (MSCs) play an important role in hematopoietic stem cell (HSC) maintenance, proliferation, and apoptosis. DNA methyltransferase 1 (DNMT1) is considered an essential factor in the maintenance of HSCs in mammalian cells. Therefore, this study was conducted to evaluate the mRNA expression level of DNMT1 during cord blood (CB)-HSC ex vivo expansion with MSCs. METHODS: Ex vivo cultures of CB-HSCs were performed in three culture conditions for 7 days: cytokines, cytokines with MSCs, and only MSCs...
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401097/enhanced-differentiation-of-mesenchymal-stromal-cells-by-three-dimensional-culture-and-azacitidine
#14
Yoo-Jin Bae, Yong-Rim Kwon, Hye Joung Kim, Seok Lee, Yoo-Jin Kim
BACKGROUND: Mesenchymal stromal cells (MSCs) are useful for cell therapy because of their potential for multilineage differentiation. However, MSCs that are expanded in traditional two-dimensional (2D) culture systems eventually lose their differentiation abilities. Therefore, we investigated whether azacitidine (AZA) supplementation and three-dimensional culture (3D) could improve the differentiation properties of MSCs. METHODS: 2D- or 3D-cultured MSCs which were prepared according to the conventional or hanging-drop culture method respectively, were treated with or without AZA (1 µM for 72 h), and their osteogenic and adipogenic differentiation potential were determined and compared...
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401096/regulation-of-the-embryonic-erythropoietic-niche-a-future-perspective
#15
REVIEW
Ayako Yumine, Stuart T Fraser, Daisuke Sugiyama
The production of red blood cells, termed erythropoiesis, occurs in two waves in the developing mouse embryo: first primitive erythropoiesis followed by definitive erythropoiesis. In the mouse embryo, both primitive and definitive erythropoiesis originates in the extra-embryonic yolk sac. The definitive wave then migrates to the fetal liver, fetal spleen and fetal bone marrow as these organs form. The fetal liver serves as the major organ for hematopoietic cell expansion and erythroid maturation after mid-gestation...
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401095/a-neutrophil-phagocytosing-bacteria
#16
Fabio Miglietta, Claudio Palumbo, Maria Aguglia, Giambattista Lobreglio
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401094/refractory-anemia-with-ring-sideroblasts-and-thrombocytosis
#17
Sarita Pradhan
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401093/lymphoglandular-bodies-in-bone-marrow-aspirate-smears
#18
Swachi Jain, Smeeta Gajendra, Ritesh Sachdev
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401092/the-consortium-for-improving-survival-of-lymphoma-cisl-recent-achievements-and-future-perspective
#19
REVIEW
Cheolwon Suh, Byeong-Bae Park, Won Seog Kim
No abstract text is available yet for this article.
March 2017: Blood Research
https://www.readbyqxmd.com/read/28401091/alternative-approaches-to-preserve-msc-progenitor-potency
#20
EDITORIAL
Nayoun Kim, Seok-Goo Cho
No abstract text is available yet for this article.
March 2017: Blood Research
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