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Progress in the Chemistry of Organic Natural Products

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https://www.readbyqxmd.com/read/27538412/erratum-to-dimeric-sesquiterpenoids
#1
Shang-Gao Liao, Jian-Min Yue
No abstract text is available yet for this article.
2016: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/27380407/the-laurencia-paradox-an-endless-source-of-chemodiversity
#2
Maria Harizani, Efstathia Ioannou, Vassilios Roussis
Nature, the most prolific source of biological and chemical diversity, has provided mankind with treatments for health problems since ancient times and continues to be the most promising reservoir of bioactive chemicals for the development of modern drugs. In addition to the terrestrial organisms that still remain a promising source of new bioactive metabolites, the marine environment, covering approximately 70% of the Earth's surface and containing a largely unexplored biodiversity, offers an enormous resource for the discovery of novel compounds...
2016: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/27380406/ingenane-diterpenoids
#3
Giovanni Appendino
Despite a more recent isolation and chemical characterization when compared to phorbol, along with its chemical instability, limited distribution in Nature, and scarce availability, ingenol is the only Euphorbia diterpenoid that has undergone successful pharmaceutical development, with ingenol 3-angelate (ingenol mebutate, Picato(®)) entering the pharmaceutical market in 2012 for the treatment of actinic keratosis. The phytochemical, chemical, and biological literature on members of the ingenane class of diterpenoids is reviewed from their first isolation in 1968 through 2015, highlighting unresolved issues both common to phorboids (biogenesis, relationship between molecular targets, and in vivo activity) and specific to ingenol derivatives (two-dimensional representation, in-out stereoisomerism, versatility of binding mode to PKC, and inconsistencies in the structural elucidation of some classes of derivatives)...
2016: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/26659109/acetogenins-from-annonaceae
#4
REVIEW
Chih-Chuang Liaw, Jing-Ru Liou, Tung-Ying Wu, Fang-Rong Chang, Yang-Chang Wu
In recent decades, annonaceous acetogenins have become highly studied plant secondary metabolites in terms of their isolation, structure elucidation, synthesis, biological evaluation, mechanism of action, and toxicity. The aim of the present contribution is to summarize chemical and biological reports published since 1997 on annonaceous acetogenins and synthetic acetogenin mimics. The compounds are considered biologically in terms of their cytotoxicity for cancer cell lines, neurotoxicity, pesticidal effects, and miscellaneous activities...
2016: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/26659108/dimeric-sesquiterpenoids
#5
REVIEW
Shang-Gao Liao, Jian-Min Yue
It is widely accepted that a large number of proteins that are responsible for cellular function exist as dimers or need to be activated by dimerization before mediating certain signaling pathways. Simultaneously targeting both monomeric moieties of the dimeric proteins has shown potential in the development of various therapeutic agents. As dimeric molecules might be able to act on both moieties of a dimeric protein, dimeric sesquiterpenoids (DSs), which are generated biogenetically from coupling of two sesquiterpenoid molecules, are in essence potential biologically active molecules, and have attracted in recent years great attention for their peculiar structures and biological activities...
2016: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/25632564/the-series-progress-in-the-chemistry-of-organic-natural-products-75-years-of-service-in-the-development-of-natural-product-chemistry
#6
Rudolf Werner Soukup, Klara Soukup
No abstract text is available yet for this article.
2015: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/25632563/vibrational-circular-dichroism-absolute-configuration-determination-of-natural-products
#7
Pedro Joseph-Nathan, Bárbara Gordillo-Román
No abstract text is available yet for this article.
2015: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/25632562/nuclear-magnetic-resonance-in-the-structural-elucidation-of-natural-products
#8
William F Reynolds, Eugene P Mazzola
No abstract text is available yet for this article.
2015: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/25632561/mass-spectrometry-in-natural-product-structure-elucidation
#9
Herbert Budzikiewicz
No abstract text is available yet for this article.
2015: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/25632560/structure-elucidation-of-natural-compounds-by-x-ray-crystallography
#10
Ulrike Wagner, Christoph Kratky
No abstract text is available yet for this article.
2015: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/25632559/foreword-methodology
#11
Kinghorn A D, Falk H, Kobayashi J
No abstract text is available yet for this article.
2015: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/25296440/genome-mining-concept-and-strategies-for-natural-product-discovery
#12
REVIEW
Markus Nett
No abstract text is available yet for this article.
2014: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/25296439/bioactive-heterocyclic-natural-products-from-actinomycetes-having-effects-on-cancer-related-signaling-pathways
#13
REVIEW
Masami Ishibashi
No abstract text is available yet for this article.
2014: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/25296438/a-colorful-history-the-evolution-of-indigoids
#14
REVIEW
Nicolas Gaboriaud-Kolar, Sangkil Nam, Alexios-Leandros Skaltsounis
No abstract text is available yet for this article.
2014: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/25296437/pharmacognosy-of-black-cohosh-the-phytochemical-and-biological-profile-of-a-major-botanical-dietary-supplement
#15
REVIEW
Feng Qiu, James B McAlpine, Elizabeth C Krause, Shao-Nong Chen, Guido E Pauli
No abstract text is available yet for this article.
2014: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/24597429/bilirubin-jekyll-and-hyde-pigment-of-life-pursuit-of-its-structure-through-two-world-wars-to-the-new-millenium
#16
David A Lightner
No abstract text is available yet for this article.
2013: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/23781707/progress-in-the-chemistry-of-organic-natural-products-the-chemistry-of-mycotoxins
#17
REVIEW
S Bräse, F Gläser, C S Kramer, S Lindner, A M Linsenmeier, K-S Masters, A C Meister, B M Ruff, S Zhong
No abstract text is available yet for this article.
2013: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/23556317/chemical-constituents-of-bryophytes-bio-and-chemical-diversity-biological-activity-and-chemosystematics
#18
Yoshinori Asakawa, Agnieszka Ludwiczuk, Fumihiro Nagashima
No abstract text is available yet for this article.
2013: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/23556316/asymmetric-organocatalysis-in-natural-product-syntheses
#19
Mario Waser
No abstract text is available yet for this article.
2012: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/21833839/withanolides-and-related-steroids
#20
REVIEW
Rosana I Misico, Viviana E Nicotra, Juan C Oberti, Gloria Barboza, Roberto R Gil, Gerardo Burton
No abstract text is available yet for this article.
2011: Progress in the Chemistry of Organic Natural Products
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