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Journal of the International Association of Providers of AIDS Care

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https://www.readbyqxmd.com/read/27909114/conservative-treatment-of-chronic-subdural-hematoma-in-hiv-associated-thrombocytopenia-with-tranexamic-acid
#1
Raja K Kutty, Anil Kumar Peethambaran, Sunilkumar, M Anilkumar
Chronic subdural hematomas (CSDHs) and its management comprise a majority work in a neurosurgical specialty. The effectiveness of surgery is beyond doubt and sometimes even lifesaving in severe cases. However, the straightforward surgery is sometimes complicated by the associated comorbidities of the patient. Comorbidities in the form of coagulopathies secondary to chronic liver diseases, drugs (warfarin, ecosprin, clopidogrel), thrombocytopenia secondary to systemic illness are always a challenge to deal with in patients with CSDH...
December 1, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27903950/shout-it-now-a-mobile-hct-model-employing-technology-and-edutainment-in-south-africa
#2
Joseph Daniels, Arnost Komarek, Bruce Forgreive, Kathryn Pahl, Stephen Stafford, Laurie Campbell Bruns, Thomas Coates
BACKGROUND: Mobile HIV counseling and testing (HCT) has been effective in reaching men, women, and adolescents in South Africa. However, there is limited understanding of effective mobile HCT programs utilizing tools like technology and edutainment to increase HIV counseling and testing rates. The authors examine data from the Shout-It-Now (S-N) program that uses such tools in South Africa. METHODS: The S-N program utilizes various forms of technology and ongoing telephonic counseling within a 6-step program of HIV testing and linkage-to-care support, and program data were analyzed over an 18-month period...
November 30, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27903949/possible-drug-herb-interaction-between-herbal-supplement-containing-horsetail-equisetum-arvense-and-antiretroviral-drugs-report-of-2-cases
#3
Ezequiel Cordova, Laura Morganti, Claudia Rodriguez
The use of alternative medicines, including herbs, is common among HIV-positive patients, even in those on antiretroviral treatment. Equisetum arvense, known as "horsetail," is mainly used for its diuretic properties. There are limited data about the pharmacological properties of this compound and the potential drug-herb interactions. The authors report 2 cases in which a possible drug-herb interaction may have led to virological breakthrough in patients who were maintained on the same regimen for many years, including lamivudine (3TC)/zidovudine (ZDV)/efavirenz (EFV) and emtricitabine (FTC)/tenofovir (TDF)/EFV, respectively...
November 30, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27903948/characterizing-patients-with-very-low-level-hiv-viremia-a-community-based-study
#4
Elie Helou, Sheela Shenoi, Tassos Kyriakides, Marie-Louise Landry, Michael Kozal, Lydia Aoun Barakat
OBJECTIVE: Very-low-level viremia (VLLV) is a relatively new concept in the realm of human immunodeficiency virus (HIV) care. Newer generation assays are now able to detect plasma HIV RNA Viral Load (VL) levels as low as 20 copies/mL. The authors characterized patients with VLLV (VL between 20 and 50 copies/mL) in order to identify possible risk factors associated with virologic failure and poor clinical outcomes. METHODS: The authors reviewed 119 consecutive charts of patients with VLLV...
November 30, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27852944/retention-in-continuous-care-and-sustained-viral-suppression-examining-the-association-among-individuals-living-with-hiv
#5
Timothy N Crawford, Alice Thornton
OBJECTIVES: To examine the relationship between retention in continuous care and sustained viral suppression. METHODS: The authors retrospectively followed 653 persons who were virally suppressed and seeking care at an infectious disease clinic in Kentucky for an average of 6 years to determine the rates of retention in medical care (≥2 visits separated by ≥3 months within a 12-month period) and sustained viral suppression (<400 copies/mL). A generalized linear mixed model was used to determine an association between retention and suppression over time...
November 16, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27733639/strongyloidiasis-related-iris-a-case-report-and-literature-review
#6
Haggai Bar-Yoseph, Yaniv Zohar, Margalit Lorber
Helminthic infection and HIV have been reported to coexist, particularly in sub-Saharan African patients living with HIV. Strongyloidiasis is one of the most common helminths, usually leading to cutaneous and gastrointestinal (GI) symptoms. In the immunocompromised host, this infection can lead to strongyloidiasis hyperinfection syndrome (SHS), not common in HIV-infected patients. Immune reconstitution inflammatory syndrome (IRIS) can follow the initiation of antiretroviral therapy (ART), with a variety of presentations...
October 12, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27708115/changing-clinician-practices-and-attitudes-regarding-the-use-of-antiretroviral-therapy-for-hiv-treatment-and-prevention-results-from-the-hptn-065-study
#7
Kate Buchacz, Jennifer Farrior, Geetha Beauchamp, Laura McKinstry, Ann E Kurth, Barry S Zingman, Fred M Gordin, Deborah Donnell, Kenneth H Mayer, Wafaa M El-Sadr, Bernard Branson
As part of the HPTN065 study in the Bronx, New York and Washington, the authors, we surveyed clinicians to assess for shifts in their practices and attitudes around HIV treatment and prevention. Antiretroviral therapy (ART)-prescribing clinicians at 39 HIV care sites were offered an anonymous Web-based survey at baseline (2010-2011) and at follow-up (2013). The 165 respondents at baseline and 141 respondents at follow-up had similar characteristics-almost 60% were female, median age was 47 years, two-thirds were physicians, and nearly 80% were HIV specialists...
October 5, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27655836/diagnosis-and-management-of-a-pancreaticopleural-fistula-in-a-patient-with-aids-and-a-large-pleural-effusion
#8
Margaret J Blayney, Andy Nguyen, David M Aboulafia
Pleural effusions typically present with nonspecific pulmonary complaints in the setting of either acute or chronic diseases. In the general population, these illnesses include congestive heart failure, infection, and malignancy. However, in people living with HIV/AIDS (PLWHA), pleural effusions often result from opportunistic infections and AIDS-defining malignancies, such as Kaposi sarcoma and non-Hodgkin lymphoma. Since the introduction of highly active antiretroviral therapy, there has been a decline in the frequency of AIDS-defining opportunistic infections and AIDS-defining cancers and an increase in certain non-AIDS-defining malignancies including lung cancer...
September 21, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27655835/hiv-stigma-perspectives-from-kenyan-child-caregivers-and-adolescents-living-with-hiv
#9
Megan Song McHenry, Winstone M Nyandiko, Michael L Scanlon, Lydia J Fischer, Carole I McAteer, Josephine Aluoch, Violet Naanyu, Rachel C Vreeman
Stigma shapes all aspects of HIV prevention and treatment, yet there are limited data on how HIV-infected youth and their families are affected by stigma in sub-Saharan Africa. The authors conducted a qualitative study using focus group discussions among 39 HIV-infected adolescents receiving care at HIV clinics in western Kenya and 53 caregivers of HIV-infected children. Participants felt that while knowledge and access to treatment were increasing, many community members still held negative and inaccurate views about HIV, including associating it with immorality and believing in transmission by casual interactions...
September 21, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27644759/patterns-of-systemic-hypertension-among-adults-with-perinatally-acquired-hiv
#10
Patrick Ryscavage, Thomas Macharia, Lino R Trinidad, Susan Lovelace, Vicki Tepper, Robert Redfield
Patients with perinatally acquired HIV may be at risk for the development of age-related non-AIDS diseases. The primary aim of this study was to describe patterns of systemic hypertension among a cohort of adults (≥18 years) with perinatally acquired HIV. A retrospective cohort study was conducted among adults (≥18 years) with perinatally acquired HIV infection. Primary outcomes included documentation of systemic hypertension as well as several additional non-AIDS-associated illnesses. Systemic hypertension incidence rates and rate ratios (RRs) were calculated among groups aged ≥18 and <18 years at the time of hypertension diagnosis...
September 19, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27635015/factors-associated-with-returning-at-home-specimen-collection-kits-for-hiv-testing-among-internet-using-men-who-have-sex-with-men
#11
Alexandra V Ricca, Eric W Hall, Christine M Khosropour, Patrick S Sullivan
BACKGROUND: In the United States, men who have sex with men (MSM) are known to disproportionately have HIV. The authors sought to describe the acceptability of providing at-home dried blood spot specimen collection kits for HIV testing among MSM. METHODS: Between August 2010 and December 2010, the authors recruited Internet-using, HIV-negative or -unknown MSM to participate in a 12-month study of behavioral risks. Eligible participants were mailed an at-home HIV test...
September 15, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27629869/significant-improvements-are-needed-in-hiv-care-continuum-to-meet-90-90-90-targets-in-georgia
#12
Nikoloz Chkhartishvili, Otar Chokoshvili, Natia Dvali, Akaki Abutidze, Lali Sharvadze, Tengiz Tsertsvadze
The objective of this report was to assess Georgia's progress toward Joint United Nations Programme on HIV/AIDS 90-90-90 targets over the period between 2011 and 2015. The number of HIV-positive persons was estimated using Spectrum software. Number of persons diagnosed, on antiretroviral therapy (ART) and virally suppressed were quantified using data from the national AIDS health information system. By the end of 2015, out of the estimated 7100 persons living with HIV, 62% were diagnosed, 38% were on ART, and 32% were virally suppressed...
September 14, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27629868/prescription-of-pneumocystis-jiroveci-pneumonia-prophylaxis-in-hiv-infected-patients
#13
Xia Lin, Shikha Garg, Christine L Mattson, Qingwei Luo, Jacek Skarbinski
The US treatment guidelines recommend Pneumocystis jiroveci pneumonia (PCP) prophylaxis for all HIV-infected persons with a CD4 count <200 cells/mm(3) (ie, eligible for PCP prophylaxis). However, some studies suggest PCP prophylaxis may be unnecessary in virally suppressed patients. Using national data of HIV-infected adults receiving medical care in the United States during 2009 to 2012, the authors assessed the weighted percentage of eligible patients who were prescribed PCP prophylaxis and the independent association between PCP prophylaxis prescription and viral suppression...
September 14, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27629867/a-microfinance-program-targeting-people-living-with-hiv-in-uganda-client-characteristics-and-program-impact
#14
Sebastian Linnemayr, Lydia Buzaalirwa, James Balya, Glenn Wagner
HIV has disproportionately affected economically vulnerable populations. HIV medical care, including antiretroviral therapy, successfully restores physical health but can be insufficient to achieve social and economic health. It may therefore be necessary to offer innovative economic support programs such as providing business training and microcredit tailored to people living with HIV/AIDS. However, microfinance institutions have shown reluctance to reach out to HIV-infected individuals, resulting in nongovernment and HIV care organizations providing these services...
September 14, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27629866/understanding-determinants-of-racial-and-ethnic-disparities-in-viral-load-suppression-a-data-mining-approach
#15
Daniel J Feller, Bruce D Agins
Racial and ethnic disparities in viral load suppression (VLS) have been well documented among people living with HIV (PLWH). The authors hypothesized that a contemporary analytic technique could reveal factors underlying these disparities and provide more explanatory power than broad stereotypes. Classification and regression tree analysis was used to detect factors associated with VLS among 11 419 adult PLWH receiving treatment from 186 New York State HIV clinics in 2013. A total of 8885 (77.8%) patients were virally suppressed...
September 14, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27619537/the-relationship-of-social-support-and-neighborhood-perceptions-among-individuals-with-hiv
#16
Enbal Shacham, Julia D López, Nur F Önen, Edgar T Overton
Social support has been noted to improve health outcomes for individuals with HIV. Understanding how neighborhoods contribute to feelings of social support is beneficial to create environments where populations with HIV can be supported. This study assessed the relationship between neighborhood perceptions and social support with HIV management. A total of 201 individuals were recruited; individuals with HIV, 18 years or older, who were eligible to participate in the 2-hour interview. Psychiatric diagnostic interviews were conducted alongside assessments of social support and neighborhood perceptions; biomedical markers were abstracted from medical records...
September 12, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27502831/community-federally-qualified-health-centers-as-homes-for-hiv-preexposure-prophylaxis-perspectives-from-south-florida
#17
Susanne Doblecki-Lewis, Deborah Jones
Preexposure prophylaxis (PrEP) for HIV has the potential to reduce HIV incidence in highly affected areas. The Southeastern United States is disproportionately impacted by HIV, and 3 counties in South Florida have the highest incidence of new HIV infections in the United States. This study explored the feasibility, acceptability, and uptake of PrEP in South Florida. Focus groups consisting of providers, administrators, and case managers at HIV-servicing community health centers and federally qualified health centers in South Florida reported broad support but low implementation of PrEP...
November 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27000130/physician-preferences-for-physician-targeted-hiv-testing-campaigns
#18
Monisha Arya, Ashley L Phillips, Richard L Street, Thomas P Giordano
The U.S. Centers for Disease Control and Prevention and the U.S. Preventive Services Task Force issued HIV testing recommendations, encouraging physicians to routinely test all adult patients for HIV. Studies have found that not all physicians are abiding by these guidelines, but that physician recommendations for HIV testing could encourage patients to get tested. Our study sought to determine physician preferences for a physician-targeted campaign to encourage them to offer HIV tests to their patients. The study took place across 19 publicly-funded community health centers...
November 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/26497751/delivery-of-hiv-transmission-risk-reduction-services-by-hiv-care-providers-in-the-united-states-2013
#19
Linda Beer, John Weiser, Brady T West, Chris Duke, Garrett Gremel, Jacek Skarbinski
OBJECTIVES: Evidence-based guidelines have long recommended that HIV care providers deliver HIV transmission risk-reduction (RR) services, but recent data are needed to assess their adoption. METHODS: The authors surveyed a probability sample of 1234 US HIV care providers on delivery of 9 sexual behavior- and 7 substance use-related HIV transmission RR services and created an indicator of "adequate" delivery of services in each area, defined as performing approximately 70% or more of applicable services...
November 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/25146972/prevalence-and-risk-factors-for-overweight-and-obesity-among-hiv-infected-adults-in-dar-es-salaam-tanzania
#20
Helen Semu, Rachel M Zack, Enju Liu, Ellen Hertzmark, Donna Spiegelman, Kevin Sztam, Claudia Hawkins, Guerino Chalamila, Aisa Muya, Hellen Siril, Ramadhani Mwiru, Deo Mtasiwa, Wafaie Fawzi
BACKGROUND: Overweight and obesity are increasingly prevalent among HIV-infected populations. We describe their prevalence and associated risk factors among HIV-infected adults in Dar es Salaam, Tanzania. METHODS: A cross-sectional study was conducted to determine the proportion of patients who were overweight or obese at enrollment to care and treatment centres from 2004 to 2011. Multivariate relative risk regression models were fit to identify risk factors. RESULTS:  A total of 53 825 patients were included in the analysis...
November 2016: Journal of the International Association of Providers of AIDS Care
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