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Journal of the International Association of Providers of AIDS Care

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https://www.readbyqxmd.com/read/28090799/national-hiv-care-continua-for-key-populations
#1
Somya Gupta, Reuben Granich
We reviewed published national HIV care continua for men who have sex with men (MSM), people who inject drugs (PWID), and female sex workers (FSWs) to track progress toward the 90-90-90 target. We searched the Internet, PubMed, surveillance reports, United Nations Programme on HIV/AIDS country reports, US President's Emergency Plan for AIDS Relief country/regional operational plans, and conference abstracts for the continua and graded them on quality. We found 12 continua for MSM, 7 for PWID, and 5 for FSW from 12 countries...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28088870/fatal-relapse-of-myelodysplastic-syndrome-in-a-patient-with-hiv-hepatitis-c-coinfection-treated-with-simeprevir-sofosbuvir
#2
Efemena Michael Diejomaoh, Joseph Clayton Gathe, Carl Craig Mayberry, John Benjamin Clemmons, Bernie Miguel, Alan Glombicki, Benjamin Daquioag
Registrational studies and observational cohorts clearly suggest sustained virologic response (SVR) rates in HIV-/hepatitis C-coinfected patients are similar to monoinfected patients when utilizing interferon-free regimens, and this can be accomplished with agents that are well tolerated with minimal adverse events. These randomized trials that led to the approval of several of our new direct-acting antiviral agents, however, specifically excluded patients who had significant comorbidities and none to our knowledge accepted patients with a history of cancer...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28088869/moving-from-public-health-failure-to-opportunity
#3
Reuben Granich, José M Zuniga
No abstract text is available yet for this article.
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28074681/community-based-exercise-in-the-context-of-hiv
#4
Anna Li, Taylor McCabe, Erin Silverstein, Stephanie Dragan, Nancy M Salbach, Mehdi Zobeiry, Sarah Beldick, Chris Godi, Kelly K O'Brien
OBJECTIVE: To identify factors to consider for developing and implementing a community-based exercise (CBE) program for people living with HIV (PLWH). METHODS: We conducted a qualitative descriptive study using semi-structured interviews with PLWH, rehabilitation professionals, and recreation providers from Canada and the United Kingdom. We asked participants to describe their experience with exercise, facilitators, and barriers to accessing and participating in exercise, and factors to consider in developing a CBE program for PLWH...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28071205/long-term-liver-diseases-after-initiation-of-antiretroviral-therapy-in-hiv-infected-patients-with-and-without-hbv-or-hcv-coinfection
#5
Sithakom Phusanti, Kwanhatai Manosudprasit, Somnuek Sungkanuparph
Coinfection of hepatitis B virus (HBV) or hepatitis C virus (HCV) with HIV is common and associated with increased mortality and increased risk of progression to chronic liver disease. We aimed to study long-term liver diseases after initiation of antiretroviral therapy (ART) in HIV-infected patients with and without HBV or HCV coinfection. A retrospective cohort of 92 patients (32 patients with HBV and/or HCV coinfection) was analyzed. Overall mean age was 38.3 years, and 54.3% were males. Immunological and virological responses were similar between the 2 groups ( P > ...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28050923/incidence-of-opportunistic-infections-among-hiv-positive-adults-on-highly-active-antiretroviral-therapy-in-a-teaching-hospital-india
#6
Nandita Shenoy, John T Ramapuram, Ashok Shenoy, Junaid Ahmed, N Srikant
Oral manifestations in HIV infections are numerous and some of these are acknowledged as being of great importance in the early diagnosis of the disease. Many HIV-associated oral infections occur early in HIV disease, not infrequently as the presenting sign or symptom. Thus, early detection of the associated oral opportunistic infections should, in many cases, result in earlier diagnosis of HIV infection. Cytology, a simple, painless, and inexpensive method, has become a preferred method and was used in our study for early diagnosis of certain lesions...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28043197/zidovudine-versus-tenofovir-based-antiretroviral-therapy-for-the-initial-treatment-of-hiv-infection-in-the-ethnic-minority-region-of-liangshan-prefecture-sichuan-province-china
#7
Cedric P Cheung, Wen Hong Lai, Jonathan Shuter
BACKGROUND: Tenofovir (TDF)-based highly active antiretroviral therapy (HAART), as recommended by the World Health Organization guidelines for HIV-naive patients, has been limited in resource-constrained settings. The aim of this study was to evaluate the effectiveness of zidovudine-(ZDV) versus TDF-based HAART in the Yi minority region of Sichuan Province, China at a single HIV treatment center. METHODS: The primary end point was the attainment of an HIV viral load <50 copies/mL...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28043196/clinico-epidemiological-profile-of-viral-sexually-transmitted-infections-in-seropositive-patients-attending-a-tertiary-care-hospital-in-north-india
#8
Shikha Chugh, Vijay Kumar Garg, Rashmi Sarkar, Kabir Sardana
Sexually transmitted diseases are a major public health problem both in developing and in developed countries, and especially with the co-synergy with HIV infection, there is an increasing need to have a proper understanding of the clinicodemographic patterns of sexually transmitted infections (STIs) for planning and implementing control strategies. Worldwide, there is an increased preponderance of viral STIs. Increasing incidence and altered clinical presentation of viral STIs in patients with HIV pose a diagnostic challenge; thereby, we studied the demographic profile of HIV-seropositive patients and compared clinical manifestations of viral STIs in HIV-seropositive patients to those in seronegative individuals...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27909114/conservative-treatment-of-chronic-subdural-hematoma-in-hiv-associated-thrombocytopenia-with-tranexamic-acid
#9
Raja K Kutty, Anil Kumar Peethambaran, Sunilkumar, M Anilkumar
Chronic subdural hematomas (CSDHs) and its management comprise a majority work in a neurosurgical specialty. The effectiveness of surgery is beyond doubt and sometimes even lifesaving in severe cases. However, the straightforward surgery is sometimes complicated by the associated comorbidities of the patient. Comorbidities in the form of coagulopathies secondary to chronic liver diseases, drugs (warfarin, ecosprin, clopidogrel), thrombocytopenia secondary to systemic illness are always a challenge to deal with in patients with CSDH...
December 1, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27903950/shout-it-now-a-mobile-hct-model-employing-technology-and-edutainment-in-south-africa
#10
Joseph Daniels, Arnost Komarek, Bruce Forgreive, Kathryn Pahl, Stephen Stafford, Laurie Campbell Bruns, Thomas Coates
BACKGROUND: Mobile HIV counseling and testing (HCT) has been effective in reaching men, women, and adolescents in South Africa. However, there is limited understanding of effective mobile HCT programs utilizing tools like technology and edutainment to increase HIV counseling and testing rates. The authors examine data from the Shout-It-Now (S-N) program that uses such tools in South Africa. METHODS: The S-N program utilizes various forms of technology and ongoing telephonic counseling within a 6-step program of HIV testing and linkage-to-care support, and program data were analyzed over an 18-month period...
November 30, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27903949/possible-drug-herb-interaction-between-herbal-supplement-containing-horsetail-equisetum-arvense-and-antiretroviral-drugs-report-of-2-cases
#11
Ezequiel Cordova, Laura Morganti, Claudia Rodriguez
The use of alternative medicines, including herbs, is common among HIV-positive patients, even in those on antiretroviral treatment. Equisetum arvense, known as "horsetail," is mainly used for its diuretic properties. There are limited data about the pharmacological properties of this compound and the potential drug-herb interactions. The authors report 2 cases in which a possible drug-herb interaction may have led to virological breakthrough in patients who were maintained on the same regimen for many years, including lamivudine (3TC)/zidovudine (ZDV)/efavirenz (EFV) and emtricitabine (FTC)/tenofovir (TDF)/EFV, respectively...
November 30, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27903948/characterizing-patients-with-very-low-level-hiv-viremia-a-community-based-study
#12
Elie Helou, Sheela Shenoi, Tassos Kyriakides, Marie-Louise Landry, Michael Kozal, Lydia Aoun Barakat
OBJECTIVE: Very-low-level viremia (VLLV) is a relatively new concept in the realm of human immunodeficiency virus (HIV) care. Newer generation assays are now able to detect plasma HIV RNA Viral Load (VL) levels as low as 20 copies/mL. The authors characterized patients with VLLV (VL between 20 and 50 copies/mL) in order to identify possible risk factors associated with virologic failure and poor clinical outcomes. METHODS: The authors reviewed 119 consecutive charts of patients with VLLV...
November 30, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27852944/retention-in-continuous-care-and-sustained-viral-suppression-examining-the-association-among-individuals-living-with-hiv
#13
Timothy N Crawford, Alice Thornton
OBJECTIVES: To examine the relationship between retention in continuous care and sustained viral suppression. METHODS: The authors retrospectively followed 653 persons who were virally suppressed and seeking care at an infectious disease clinic in Kentucky for an average of 6 years to determine the rates of retention in medical care (≥2 visits separated by ≥3 months within a 12-month period) and sustained viral suppression (<400 copies/mL). A generalized linear mixed model was used to determine an association between retention and suppression over time...
November 16, 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28084190/depression-at-treatment-initiation-predicts-hiv-antiretroviral-adherence-in-uganda
#14
Glenn J Wagner, Mary Slaughter, Bonnie Ghosh-Dastidar
We examined the relationship between depression (symptom type, diagnostic severity, and change over time) and adherence to HIV antiretroviral therapy (ART) with data from 3 longitudinal studies (N = 1021) of patients starting ART in Uganda. The Patient Health Questionnaire was used to assess depressive symptoms (total score; somatic and cognitive subscales) and categorize severity level. At baseline, 9% had major depression and 30% had minor depression; 82% were adherent (reported no missed ART doses in the past 7 days) at month 6 and 85% at month 12...
January 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28084189/impact-of-unplanned-care-interruption-on-cd4-response-early-after-art-initiation-in-a-nigerian-cohort
#15
Aimalohi A Ahonkhai, Juliet Adeola, Bolanle Banigbe, Ifeyinwa Onwuatuelo, Abdulkabir B Adegoke, Ingrid V Bassett, Elena Losina, Kenneth A Freedberg, Prosper Okonkwo, Susan Regan
The authors conducted a retrospective cohort study of unplanned care interruption (UCI) among adults initiating antiretroviral therapy (ART) from 2009 to 2011 in a Nigerian clinic. The authors used repeated measures regression to model the impact of UCI on CD4 count upon return to care and rate of CD4 change on ART. Among 2496 patients, 83% had 0, 15% had 1, and 2% had ≥2 UCIs. Mean baseline CD4 for those with 0, 1, or ≥2 UCIs was 228/cells/mm(3), 355/cells/mm(3), and 392/cells/mm(3) ( P < .0001), respectively...
January 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/25331222/prevalence-of-hiv-associated-neurocognitive-disorder-hand-among-patients-attending-a-tertiary-health-facility-in-northern-nigeria
#16
Abdulkareem Jika Yusuf, Abdulaziz Hassan, Aisha Indo Mamman, Haruna Mohammed Muktar, Aishatu Maude Suleiman, Olusegun Baiyewu
BACKGROUND: HIV-associated neurocognitive disorder (HAND) is a great source of morbidity in sub-Saharan African region. However, the magnitude of this problem remains largely uninvestigated despite having the largest number of population with HIV/AIDS. The aim of this study is to determine the prevalence of HAND among patients attending a tertiary health facility in Nigeria. METHOD: We conducted a cross-sectional study among HIV-positive patients on antiretroviral therapy (ART) for at least 1 year...
January 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/21852689/substance-abuse-and-hiv-aids-in-the-caribbean
#17
Iliana Alexandra Angulo-Arreola, Francisco I Bastos, Steffanie A Strathdee
The Caribbean and Central America represent a formidable challenge for researchers and policy makers in the HIV field, due to their pronounced heterogeneity in terms of social, economic, and cultural contexts and the different courses the HIV epidemic has followed in the region. Such contrasting contexts and epidemics can be exemplified by 2 countries that share the island of Hispaniola, the French Creole-speaking Haiti, and the Spanish-speaking Dominican Republic. Haiti has experienced the worst epidemics outside of sub-Saharan Africa...
January 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27502831/community-federally-qualified-health-centers-as-homes-for-hiv-preexposure-prophylaxis-perspectives-from-south-florida
#18
Susanne Doblecki-Lewis, Deborah Jones
Preexposure prophylaxis (PrEP) for HIV has the potential to reduce HIV incidence in highly affected areas. The Southeastern United States is disproportionately impacted by HIV, and 3 counties in South Florida have the highest incidence of new HIV infections in the United States. This study explored the feasibility, acceptability, and uptake of PrEP in South Florida. Focus groups consisting of providers, administrators, and case managers at HIV-servicing community health centers and federally qualified health centers in South Florida reported broad support but low implementation of PrEP...
November 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/27000130/physician-preferences-for-physician-targeted-hiv-testing-campaigns
#19
Monisha Arya, Ashley L Phillips, Richard L Street, Thomas P Giordano
The U.S. Centers for Disease Control and Prevention and the U.S. Preventive Services Task Force issued HIV testing recommendations, encouraging physicians to routinely test all adult patients for HIV. Studies have found that not all physicians are abiding by these guidelines, but that physician recommendations for HIV testing could encourage patients to get tested. Our study sought to determine physician preferences for a physician-targeted campaign to encourage them to offer HIV tests to their patients. The study took place across 19 publicly-funded community health centers...
November 2016: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/26497751/delivery-of-hiv-transmission-risk-reduction-services-by-hiv-care-providers-in-the-united-states-2013
#20
Linda Beer, John Weiser, Brady T West, Chris Duke, Garrett Gremel, Jacek Skarbinski
OBJECTIVES: Evidence-based guidelines have long recommended that HIV care providers deliver HIV transmission risk-reduction (RR) services, but recent data are needed to assess their adoption. METHODS: The authors surveyed a probability sample of 1234 US HIV care providers on delivery of 9 sexual behavior- and 7 substance use-related HIV transmission RR services and created an indicator of "adequate" delivery of services in each area, defined as performing approximately 70% or more of applicable services...
November 2016: Journal of the International Association of Providers of AIDS Care
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