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Journal of Integrative Medicine

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https://www.readbyqxmd.com/read/30077645/protective-roles-of-vigna-subterranea-bambara-nut-in-rats-with-aspirin-induced-gastric-mucosal-injury
#1
Morufu Eyitayo Balogun, Elizabeth Enohnyaket Besong, Jacinta Nkechi Obimma, Ogochukwu Sophia Mbamalu, Fankou Serges Athanase Djobissie
OBJECTIVE: Vigna subterranea is widely consumed as a traditional staple food in Nigeria and some West African countries. The ethanolic seed extract of V. subterranea (EEVS) was investigated for its gastroprotective effects on aspirin plus pylorus ligation-induced gastric ulcerated rats using an in vivo assay. METHODS: Gastric mucosal ulceration was induced experimentally in Groups 2 to 5 using aspirin plus pylorus ligation. Rats in Group 1 were orally pretreated with 3% Tween 80 only as normal control...
August 1, 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/30100269/a-brief-illustration-of-the-official-national-standards-for-the-safe-use-of-cupping-therapy-hijama-in-saudi-arabia
#2
Tamer Aboushanab, Saud AlSanad
Cupping therapy (Hijama in Arabic) is a popular traditional treatment especially in Asia, the Middle East and Central Europe. Traditionally, cupping therapy has been one of the most used practices in Saudi Arabia. Standardization of the practice of cupping therapy is a very important step to eliminate or reduce any adverse events related to cupping. This article gives a brief illustration and highlights the important points of the first accredited Saudi Arabian standards for the safe use of cupping equipment and its applications...
July 31, 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/30007830/ethnomedicinal-phytochemical-and-pharmacological-updates-on-hygrophila-auriculata-schum-hiene-an-overview
#3
REVIEW
Neeraj K Sethiya, Nasir M Ahmed, Raeesh M Shekh, Vivek Kumar, Pawan Kumar Singh, Vipin Kumar
This article explores the most recent evidence-based information on ethnomedicinal, phytochemical and pharmacological understanding of Hygrophila auriculata for the treatment of various diseases and health conditions. Various ethnomedicinal writings suggest the use of the plant or its parts for the treatment of jaundice, oedema, gastrointestinal ailments, diarrhoea, dysentery, urinogenital disorder, gall stones, urinary calculi, kidney stone, leucorrhoea, rheumatism, tuberculosis, anaemia, body pain, constipation, skin disease, and as an aphrodisiac...
July 4, 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/30007829/evaluation-of-acute-and-subacute-toxicity-of-whole-plant-aqueous-extract-of-vernonia-mespilifolia-less-in-wistar-rats
#4
Jeremiah Oshiomame Unuofin, Gloria Aderonke Otunola, Anthony Jide Afolayan
OBJECTIVE: This study investigated the acute and subacute toxicity of whole-plant aqueous extract of Vernonia mespilifolia Less. (AEVM) in rats for evaluating its safety profile. METHODS: AEVM for the acute (2000 and 5000 mg/kg) and subacute (200, 400 and 600 mg/kg) toxicity studies was administered orally to rats according the guidelines 425 and 407 of Organization for Economic Cooperation and Development, respectively. Food and water intake as well as body and organ weight of animals were recorded...
July 4, 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/30006023/bioavailable-curcumin-formulations-a-review-of-pharmacokinetic-studies-in-healthy-volunteers
#5
REVIEW
Rohitash Jamwal
Curcumin is a widely studied natural compound which has shown tremendous in vitro therapeutic potential. Despite that, the clinical efficacy of the native curcumin is weak due to its low bioavailability and high metabolism in the gastrointestinal tract. During the last decade, researchers have come up with different formulations with a focus on improving the bioavailability of curcumin. As a result, a significant number of bioavailable curcumin-based formulations were introduced with the varying range of enhanced bioavailability...
July 4, 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/30007828/acupuncture-for-migraine-without-aura-a-systematic-review-and-meta-analysis
#6
REVIEW
Jia Xu, Fu-Qing Zhang, Jian Pei, Jun Ji
BACKGROUND: Migraine without aura (MWoA), the most common type of migraine, has great impacts on quality of life for migraineurs. Acupuncture is used in the treatment and prevention of migraine for its analgesic effects. OBJECTIVE: The aim of this systematic review and meta-analysis is to systematically assess the therapeutic and preventive effect of acupuncture treatment and its safety for MWoA. SEARCH STRATEGY: Nine electronic databases (PubMed, MEDLINE, Cochrane Library, Lilacs, Embase, China National Knowledge Infrastructure (CNKI), Chongqing VIP (CQVIP), Wanfang Data and Chinese Clinical Trial Registry (ChiCTR)) were systematically searched from their beginning through June 2017 using MeSH terms such as "acupuncture, acupuncture therapy, electro-acupuncture, ear acupuncture, acupuncture points, acupuncture analgesia," and "migraine disorders, cluster headache...
June 28, 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29929873/effects-of-vitamin-supplementation-on-inflammatory-markers-and-psychological-wellbeing-among-distressed-women-a-randomized-controlled-trial
#7
J M Oliver-Baxter, H S Whitford, D A Turnbull, M J Bond
BACKGROUND: Multivitamins are a popular supplement taken to promote physical and mental health. During periods of stress, they may have a protective role for health and wellbeing, although the current evidence of their efficacy is mixed. OBJECTIVE: To determine whether multivitamin supplementation impacts psychological and inflammatory markers of women who are experiencing psychological distress. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS: An 8-week randomized controlled trial was conducted to assess changes in both psychological state and pro-inflammatory markers of patients receiving multivitamins or placebo...
June 7, 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29891180/clinical-practice-guidelines-for-the-treatment-of-primary-liver-cancer-with-integrative-traditional-chinese-and-western-medicine
#8
Chang-Quan Ling, Jia Fan, Hong-Sheng Lin, Feng Shen, Zhen-Ye Xu, Li-Zhu Lin, Shu-Kui Qin, Wei-Ping Zhou, Xiao-Feng Zhai, Bai Li, Qing-Hui Zhou
Traditional Chinese medicine (TCM) is an important part of the treatment of primary liver cancer (PLC) in China; however, the current instructions for the integrative use of traditional Chinese and Western medicine for PLC are mostly based on expert opinion. There is no evidence-based guideline for clinical practice in this field. Therefore, the Shanghai Association of Chinese Integrative Medicine has established a multidisciplinary working group to develop this guideline, which focuses on the most important questions about the use of TCM during PLC treatment...
July 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29880257/kaempferia-parviflora-ethanol-extract-improves-self-assessed-sexual-health-in-men-a-pilot-study
#9
Richard A Stein, Kira Schmid, Jowell Bolivar, Andrew G Swick, Steven V Joyal, Steven P Hirsh
BACKGROUND: Sexual health positively correlates with overall wellbeing. Existing therapeutics to enhance male sexual health are limited by factors that include responsiveness, adherence and adverse effects. As the population ages, safe and effective interventions that preserve male sexual function are needed. Published research suggests that various preparations of Kaempferia parviflora, a plant in the Zingiberaceae (ginger) family, support cardiovascular health and may ameliorate erectile function...
July 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29866613/preliminary-optimization-of-a-chinese-herbal-medicine-formula-based-on-the-neuroprotective-effects-in-a-rat-model-of-rotenone-induced-parkinson-s-disease
#10
Xu-Xia Bao, Hui-Han Ma, Hao Ding, Wen-Wei Li, Min Zhu
OBJECTIVE: The main objective of this study was to preliminarily determine the optimum formulation of a Chinese herbal formula that may have neuroprotective effects against rotenone-induced Parkinson's disease (PD). METHODS: Seven recipes were made from Dihuang (DH, Rehmannia glutinosa Libosch), Roucongrong (RCR, Cistanche deserticola Y.C.Ma), Niuxi (NX, Achyranthes bidentata Bl.) and Shanzhuyu (SZY, Cornus officinalis Sieb. et Zucc) in different proportions, according to the principles of uniform design (4 factors 7 levels)...
July 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29866612/phytochemistry-and-biological-activities-of-heracleum-persicum-a-review
#11
REVIEW
Zahra Majidi, S N Sadati Lamardi
Heracleum persicum Desf. ex Fisch is used in Iranian traditional medicines, for the treatment of various diseases including neurological, gastrointestinal, respiratory, rheumatological and urinary tract diseases. In phytochemical analysis of H. persicum, several classes of natural chemicals including volatile (aliphatic esters, carbonyls, phenyl propenes and terpenes) and nonvolatile (flavonoids, furanocoumarins, tannins and alkaloids) constituents as well as different minerals have been identified. Scientific studies on H...
July 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29776838/hot-aqueous-leaf-extract-of-lasianthera-africana-icacinaceae-attenuates-rifampicin-isoniazid-induced-hepatotoxicity
#12
Lucky Legbosi Nwidu, Raphael Ellis Teme
OBJECTIVES: The aim of this study is to evaluate the hepatoprotective effect of Lasianthera africana (Icacinaceae) against isoniazid (INH) and rifampicin (RIF)-induced liver damage in rats. METHODS: The hepatoprotective effects of hot aqueous L. africana (HALA) leaf extract (0.1-1 g/kg) and silymarin (50 mg/kg) were assessed in a model of oxidative liver damage induced by RIF and INH (100 mg/kg each) in Wistar rats for 28 days. Biochemical markers of hepatic damage such as alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) were assessed...
July 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29759936/in-vitro-antioxidant-antilipoxygenase-and-antimicrobial-activities-of-extracts-from-seven-climbing-plants-belonging-to-the-bignoniaceae
#13
Carola Analía Torres, Cristina Marisel Pérez Zamora, María Beatriz Nuñez, Ana María Gonzalez
OBJECTIVES: This study aimed to evaluate the in vitro antioxidant capacity, to determine the anti-inflammatory effect due to lipoxygenase inhibition and to test the antimicrobial activity of ethanolic extracts from leaves of seven climbing species belonging to the Bignoniaceae family. These species are Adenocalymma marginatum (Cham.) DC., Amphilophium vauthieri DC., Cuspidaria convoluta (Vell.) A. H. Gentry, Dolichandra dentata (K. Schum.) L. G. Lohmann, Fridericia caudigera (S. Moore) L...
July 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29752140/feiji-recipe-inhibits-the-growth-of-lung-cancer-by-modulating-t-cell-immunity-through-indoleamine-2-3-dioxygenase-pathway-in-an-orthotopic-implantation-model
#14
Bin Luo, Zu-Jun Que, Zhi-Yi Zhou, Qing Wang, Chang-Sheng Dong, Yi Jiang, Bing Hu, Hui Shi, Yu Jin, Jian-Wen Liu, He-Gen Li, Lin Wang, Jian-Hui Tian
OBJECTIVE: Escape from the body's immune response is a basic characteristic of lung cancer, and indoleamine-2,3-dioxygenase (IDO) plays a key role in mediating immune escape of non-small-cell lung cancer, which leads to recurrence and metastasis. Feiji Recipe, a compound Chinese herbal medicine, has the effect of stabilizing lesions and prolonging survival in patients with lung cancer. The purpose of this study was to investigate the mechanisms underlying the anticancer properties of Feiji Recipe...
July 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29706573/evaluation-of-phenolic-composition-antioxidant-anti-inflammatory-and-anticancer-activities-of-polygonatum-verticillatum-l
#15
Sandeep Kumar Singh, Arjun Patra
OBJECTIVE: Polygonatum verticillatum (L.) All. (Ruscaceae), one of the Ashtawarga plants, is widely used for treatment of various ailments. The present study was undertaken to determine the phenolic composition, antioxidant, anti-inflammatory and anticancer activities of several extracts (petroleum ether, dichloromethane, chloroform, ethanol, and aqueous) from the rhizomes of the plant. METHODS: Coarsely powdered dry rhizome was successively extracted with different solvents of increasing polarity (petroleum ether, dichloromethane, chloroform, ethanol and water)...
July 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29691188/medicinal-plants-from-the-brazilian-amazonian-region-and-their-antileishmanial-activity-a-review
#16
REVIEW
Bruno José Martins Da Silva, Amanda Anastácia Pinto Hage, Edilene Oliveira Silva, Ana Paula Drummond Rodrigues
Leishmaniasis, a neglected disease caused by Leishmania protozoans, primarily affects people in tropical and subtropical areas. Chemotherapy based on the use of pentavalent antimonials, amphotericin B, paromomycin, miltefosine and liposomal amphotericin B is currently the only effective treatment. However, adverse effects, long-term treatment and the emergence of parasite resistance have led to the search for alternative treatments. Natural products used in traditional medicine provide an unlimited source of molecules for the identification of new drugs, and the Amazon region has abundant biodiversity that includes several species of plants and animals, providing a rich source of new products and compounds...
July 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29753429/patient-blinding-with-blunt-tip-placebo-acupuncture-needles-comparison-between-1-mm-and-2-mm-skin-press
#17
Nobuari Takakura, Miho Takayama, Morihiro Nasu, Masako Nishiwaki, Akiko Kawase, Hiroyoshi Yajima
OBJECTIVE: To investigate the influence of the depth of skin press in blunt tip placebo acupuncture needles on patient blinding and its relationship to needle diameter. METHODS: Forty healthy volunteers were enrolled as subjects for patient blinding. Four acupuncturists applied the following needles randomly at three points in each forearm: 0.18 mm and 0.25 mm diameter penetrating needles inserted to a depth of 5 mm, and 0.18 mm and 0.25 mm diameter skin-touch needles depressing the skin at the acupoint to a depth of 1 mm and 2 mm from the skin surface...
May 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29709412/phytochemical-profile-and-pharmacological-activity-of-aegle-marmelos-linn
#18
REVIEW
Bikash Manandhar, Keshav Raj Paudel, Biraj Sharma, Rajendra Karki
Aegle marmelos Linn. (Rutaceae), commonly known as "bael" in Nepal and India, is a valuable medicinal plant and is considered sacred by the Hindus. It is used to cure several diseases in the Indian traditional medicine system of Ayurveda and has had similar uses among many ethnic communities residing in Indian subcontinent for over 5000 years. Its leaves, bark, stem, fruits and seeds have been used for various medicinal purposes. Bael fruits are especially effective in the treatment of chronic diarrhea, dysentery and peptic ulcers, while they are also useful as a laxative and cure for respiratory infections...
May 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29706572/inhibitory-potentials-of-phenolic-rich-extracts-from-bridelia-ferruginea-on-two-key-carbohydrate-metabolizing-enzymes-and-fe-2-induced-pancreatic-oxidative-stress
#19
Olakunle Bamikole Afolabi, Omotade Ibidun Oloyede, Shadrack Oludare Agunbiade
OBJECTIVE: The current study was designed to evaluate the various antioxidant potentials and inhibitory effects of phenolic-rich leaf extracts of Bridelia ferruginea (BF) on the in vitro activities of some key enzymes involved in the metabolism of carbohydrates. METHODS: In this study, BF leaf free and bound phenolic-rich extracts were used. We quantified total phenolic and flavonoid contents, and evaluated several antioxidant activities using assays for ferric reducing antioxidant power, total antioxidant activity (phosphomolybdenum reducing ability), 1,1-diphenyl-2-picrylhydrazyl and thiobarbituric acid reactive species...
May 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29691190/noni-morinda-citrifolia-l-fruit-juice-delays-immunosenescence-in-the-lymphocytes-in-lymph-nodes-of-old-f344-rats
#20
Uday P Pratap, Hannah P Priyanka, Karthik R Ramanathan, Vishak Raman, Lalgi Hima, Srinivasan Thyagarajan
OBJECTIVE: Aging is associated with the development of diseases because of immunosuppression and altered functioning of the neuroendocrine system. The medicinal properties of Morinda citrifolia L. have been widely exploited for the treatment of age-associated diseases. This study aims to investigate the in vitro and in vivo effects of noni (M. citrifolia) fruit juice (NFJ) on neuro-immunomodulation in the lymph node lymphocytes of F344 rats. METHODS: Lymphocytes isolated from axillary and inguinal lymph nodes of young (3-4 months) and old (18-21 months) rats were treated in vitro with different concentrations (0...
May 2018: Journal of Integrative Medicine
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