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Urolithiasis

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https://www.readbyqxmd.com/read/28331937/whey-protein-and-albumin-effects-upon-urinary-risk-factors-for-stone-formation
#1
Camila Mithie Hattori, Hans-Göran Tiselius, Ita Pfeferman Heilberg
Protein supplements are consumed for an expected increase in muscle mass and improved exercise performance, but as their impact on lithogenic parameters are unknown, we aimed to evaluate the effects of Whey protein (WP) and Albumin upon the risk factors for nephrolithiasis. WP or Albumin supplements (one scoop/day) were administered for 3 days to 18 healthy volunteers, with 1-week washout period between them. Serum and 24-h urine samples were collected at baseline and after completing each intervention. All participants were asked to replicate their baseline diet during the subsequent urine collection...
March 22, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28324150/stress-stones-stress-recurrent-stones-a-self-propagating-cycle-difficulties-in-solving-this-dichotomy
#2
Montserrat Arzoz-Fabregas, Josep Roca-Antonio, Luis Ibarz-Servio, Dalielah Jappie-Mahomed, Allen Rodgers
Numerous studies have reported an association between stress and urolithiasis. Although urinary risk factors have been measured in several of these, compelling evidence of a causal relationship has not been established. A shortcoming is that alterations in single urinary parameters rather than ratios and quotients, which provide a more synergistic risk evaluation, have been measured. Recently, we speculated about a possible association between chronic stress and stone recurrence. This presents an intriguing dichotomy of whether stress causes stones or vice versa, or whether they are linked in a self-propagating stress-stones-stress-recurrence cycle...
March 21, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28314883/stone-former-urine-proteome-demonstrates-a-cationic-shift-in-protein-distribution-compared-to-normal
#3
Ann M Kolbach-Mandel, Neil S Mandel, Brian R Hoffmann, Jack G Kleinman, Jeffrey A Wesson
Many urine proteins are found in calcium oxalate stones, yet decades of research have failed to define the role of urine proteins in stone formation. This urine proteomic study compares the relative amounts of abundant urine proteins between idiopathic calcium oxalate stone forming and non-stone forming (normal) cohorts to identify differences that might correlate with disease. Random mid-morning urine samples were collected following informed consent from 25 stone formers and 14 normal individuals. Proteins were isolated from urine using ultrafiltration...
March 17, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28299446/do-renal-stones-that-fail-lithotripsy-require-treatment
#4
Ben Pullar, Catherine Lunter, Jane Collie, Syed Shah, Nimish Shah, Sami Hayek, Oliver J Wiseman
The rates of extracorporeal shock wave lithotripsy (SWL) appear stable in the UK. However, there is little evidence on the natural history of these calculi if SWL fails. We set to look at the effectiveness of SWL in patients with a single, previously untreated renal stone and the natural history of those stones that failed treatment. We retrospectively reviewed all data from our prospectively collected database of patients undergoing a first treatment for a single renal stone between October 2010 and November 2013...
March 15, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28286933/the-effect-of-nephrostomy-tract-infiltration-of-ketamine-on-postoperative-pain-and-peak-expiratory-flow-rate-in-patients-undergoing-tubeless-percutaneous-nephrolithotomy-a-prospective-randomized-clinical-trial
#5
Seyed Reza Hosseini, Farsad Imani, Golnar Shayanpour, Mohammad Reza Khajavi
Ketamine, as a systemic and local analgesic, has been used to reduce postoperative pain in many studies. The present study was designed to assess the analgesic efficacy of nephrostomy tract infiltration of ketamine in postoperative pain after tubeless percutaneous nephrolithotomy (PCNL). Sixty-six patients with renal stone who were candidates for PCNL were randomized to two groups with 33 patients in each group. In group K, 20 mL saline solution containing 1.5 mg/kg ketamine was infiltrated into the nephrostomy tract and in group C, 20 mL saline solution was infiltrated into the nephrostomy tract at the end of surgery...
March 12, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28275812/urinary-stone-disease-in-pediatric-and-adult-metabolic-bone-clinic-patients
#6
Andrew L Schwaderer, Abimbola Oduguwa, Kirsten Kusumi
Kidney stones are increasing in the pediatric and adult populations; similarly osteoporosis is increasingly recognized in children. While kidney stone formers are known to suffer from low bone density, metabolic bone patients have not been considered a high risk population for kidney stones. Retrospective chart review of Nationwide Children's Hospital Metabolic Bone Clinic patients from October 2009-2013. Patients were identified by ICD 9 codes for osteoporosis, osteopenia, low bone density and kidney stones...
March 8, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28260226/toward-a-new-insight-of-calcium-oxalate-stones-in-drosophila-by-micro-computerized-tomography
#7
Wen-Chi Chen, Huey-Yi Chen, Po-Chi Liao, Shih-Jing Wang, Ming-Yen Tsai, Yung-Hsiang Chen, Wei-Yong Lin
We previously developed an animal model of calcium oxalate (CaOx) deposition on the Malphigian tubules of Drosophila melanogaster as a model of urolithiasis. Here, we introduce a new tool for the study of anatomical structure for Drosophila. As a consequence of technical development, the invention of micro-computerized tomography (CT) has been introduced to the small animal, such as rat and mice. We used Drosophila as a model organism and fed the flies 0.5% lithogenic agent ethylene glycol for 3 weeks. Samples were simply prepared for further scanned by micro-CT to scan samples at 800 nm resolution...
March 4, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28258472/prevalence-of-renal-uric-acid-stones-in-the-adult
#8
Alberto Trinchieri, Emanuele Montanari
The aim of this study was to estimate uric acid renal stone prevalence rates of adults in different countries of the world. PubMed was searched for papers dealing with "urinary calculi and prevalence or composition" for the period from January 1996 to June 2016. Alternative searches were made to collect further information on specific topics. The prevalence rate of uric acid stones was computed by the general renal stone prevalence rate and the frequency of uric acid stones in each country. After the initial search, 2180 papers were extracted...
March 3, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28246885/biochemical-and-dietary-factors-of-uric-acid-stone-formation
#9
Alberto Trinchieri, Emanuele Montanari
The aim of this study was to compare the clinical characteristics of "pure" uric acid renal stone formers (UA-RSFs) with that of mixed uric acid/calcium oxalate stone formers (UC-RSFs) and to identify which urinary and dietary risk factors predispose to their formation. A total of 136 UA-RSFs and 115 UC-RSFs were extracted from our database of renal stone formers. A control group of 60 subjects without history of renal stones was considered for comparison. Data from serum chemistries, 24-h urine collections and 24-h dietary recalls were considered...
February 28, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28236022/complications-of-retrograde-intrarenal-surgery-classified-by-the-modified-clavien-grading-system
#10
Yong Xu, Zhiqian Min, Shaw P Wan, Haibo Nie, Guangjun Duan
The increase in the retrograde intrarenal surgery (RIRS) has been accompanied by the increase in complications. This study identified the factors that affected the severity of the complications using the modified Clavien classification system (MCCS). Three hundred and twenty-two consecutive RIRS performed by a single surgeon were analyzed. Data collection included demographics, clinical parameters, and perioperative and postoperative complications. The rate of adverse events for each of the Clavien grades was calculated, and statistical comparisons were made...
February 24, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28233025/emergent-versus-delayed-lithotripsy-for-obstructing-ureteral-stones-a-cumulative-analysis-of-comparative-studies
#11
Davide Arcaniolo, Marco De Sio, Jens Rassweiler, Jilian Nicholas, Estevão Lima, Giuseppe Carrieri, Evangelos Liatsikos, Vincenzo Mirone, Manoj Monga, Riccardo Autorino
OBJECTIVE: To analyze the current evidence on the use of ureteroscopy (URS) and extracorporeal shock wave lithotripsy (ESWL) for the management of obstructing ureteral stones in emergent setting. METHODS: A systematic literature review was performed up to June 2016 using Pubmed and Ovid databases to identify pertinent studies. The PRISMA criteria were followed for article selection. Separate searches were done using a combinations of several search terms: "laser lithotripsy", "ureteroscopy", "extracorporeal shock wave lithotripsy", "ESWL", "rapid", "immediate", "early", "delayed", "late", "ureteral stones", "kidney stones", "renal stones"...
February 23, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28229197/minimally-invasive-percutaneous-nephrolithotomy-vs-standard-pcnl-for-management-of-renal-stones-in-the-flank-free-modified-supine-position-single-center-experience
#12
Ahmed Sakr, Emad Salem, Mostafa Kamel, Esam Desoky, Ahmed Ragab, Mohamed Omran, Amr Fawzi, Ashraf Shahin
To assess the safety and efficacy of minimally invasive percutaneous nephrolithotomy (mPCNL) as compared to standard PCNL (sPCNL) for management of 2-3-cm renal stones in the flank-free modified supine position. Between September 2010 and December 2013, 150 patients (168 renal units) with 2-3-cm renal stones were prospectively randomized into two treatment groups; Group A (75 patients/87 renal units) treated by mPCNL and Group B (75 patients/81 renal units) treated by sPCNL. In both groups, the patients were placed in the flank-free modified supine position...
February 22, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28229196/the-impact-of-ureteral-stent-indwelling-time-on-the-treatment-of-acute-infection-caused-by-ureteral-calculi
#13
Yun-Feng Shi, Wen-Long Ju, Yi-Ping Zhu, Shu-Jie Xia, Xiao-Wen Sun
Ureteric stenting is an effective drainage method in patients with acute urinary tract infection caused by ureteral calculi; however, the optimal ureteral stent indwelling time has not been clearly defined. The aim of this study was to evaluate the effect of ureteric stent indwelling time on the treatment of acute infection secondary to urinary tract calculi. A total of 142 patients with acute infection caused by urinary tract calculi were identified retrospectively from January 2011 to August 2015 at our institution...
February 22, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28229195/predictors-for-uroseptic-shock-in-patients-who-undergo-minimally-invasive-percutaneous-nephrolithotomy
#14
Junhong Fan, Shawpong Wan, Luhao Liu, Zhijian Zhao, Zanlin Mai, Dong Chen, Wei Zhu, Zhou Yang, Lili Ou, Wenqi Wu
To identify risk factors that can predict which patient is likely to progress from systemic inflammatory response syndrome (SIRS) to uroseptic shock after minimally invasive percutaneous nephrolithotomy (MPCNL) for the upper urinary tract stones. We retrospectively reviewed 156 patients who suffered infectious complications after MPCNL from March 2014 to February 2016. Perioperative risk factors that could potentially contribute to uroseptic shock were compared to those of patients with only SIRS. 135 of the 156 patients developed to SIRS only, the remaining 21 patients progressed to uroseptic shock...
February 22, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28074231/development-of-a-novel-magnetic-resonance-imaging-acquisition-and-analysis-workflow-for-the-quantification-of-shock-wave-lithotripsy-induced-renal-hemorrhagic-injury
#15
Rajash K Handa, Paul R Territo, Philip M Blomgren, Scott A Persohn, Chen Lin, Cynthia D Johnson, Lei Jiang, Bret A Connors, Gary D Hutchins
The current accepted standard for quantifying shock wave lithotripsy (SWL)-induced tissue damage is based on morphometric detection of renal hemorrhage in serial tissue sections from fixed kidneys. This methodology is time and labor intensive and is tissue destructive. We have developed a non-destructive magnetic resonance imaging (MRI) method that permits rapid assessment of SWL-induced hemorrhagic lesion volumes in post-mortem kidneys using native tissue contrast to reduce cycle time. Kidneys of anesthetized pigs were targeted with shock waves using the Dornier Compact S lithotripter...
January 10, 2017: Urolithiasis
https://www.readbyqxmd.com/read/27999876/preface-physicochemical-biochemical-and-biological-mechanisms-of-stone-formation
#16
REVIEW
Allen L Rodgers
No abstract text is available yet for this article.
February 2017: Urolithiasis
https://www.readbyqxmd.com/read/27928586/physicochemical-mechanisms-of-stone-formation
#17
REVIEW
Allen L Rodgers
In this article, the term "physicochemical mechanism" is defined as a sequential series of steps culminating in the formation of a renal stone. Distinctions are drawn between physicochemical prerequisites for urinary supersaturation, crystallization, and stone formation. In particular, attention is focussed on the transition from crystal to stone. Emphasis is laid on crystal retention being the fundamental mechanism by which stones are formed, and mention is made of the different ways in which it can be achieved...
February 2017: Urolithiasis
https://www.readbyqxmd.com/read/27915396/accurate-stone-analysis-the-impact-on-disease-diagnosis-and-treatment
#18
REVIEW
Neil S Mandel, Ian C Mandel, Ann M Kolbach-Mandel
This manuscript reviews the requirements for acceptable compositional analysis of kidney stones using various biophysical methods. High-resolution X-ray powder diffraction crystallography and Fourier transform infrared spectroscopy (FTIR) are the only acceptable methods in our labs for kidney stone analysis. The use of well-constructed spectral reference libraries is the basis for accurate and complete stone analysis. The literature included in this manuscript identify errors in most commercial laboratories and in some academic centers...
February 2017: Urolithiasis
https://www.readbyqxmd.com/read/27915394/timelines-of-the-free-particle-and-fixed-particle-models-of-stone-formation-theoretical-and-experimental-investigations
#19
REVIEW
D J Kok, W Boellaard, Y Ridwan, V A Levchenko
Two major theories on renal stone formation will be reviewed, the "free-particle" and "fixed-particle" mechanisms. These theories combine data on intrinsic factors (inborn metabolic errors), extrinsic factors (diet), renal cell responses and the physico-chemistry and biochemistry of urine into mechanisms of stone formation. This paper describes the specific role of time in both mechanisms. The timeline of crystal- and stone formation was deducted from literature data and was measured for two stones using radioisotope decay analysis...
February 2017: Urolithiasis
https://www.readbyqxmd.com/read/27913855/what-can-the-microstructure-of-stones-tell-us
#20
REVIEW
James C Williams, Elaine Worcester, James E Lingeman
How stones are retained within the kidney while small in size is still not fully understood. In this paper, we show two examples of how stones are retained during early growth: one is growth on Randall's (interstitial) plaque, and the other is growth on mineral that has formed as a luminal plug in a terminal collecting duct. These two mechanisms of stone retention during early growth have distinctive morphologic features that can be seen by methods that show the microscopic structure of the stones. Stones growing on Randall's plaque display an apatite region that is typically not large in size (<0...
February 2017: Urolithiasis
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