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Biomedical Journal

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https://www.readbyqxmd.com/read/29433839/an-accurate-emotion-recognition-system-using-ecg-and-gsr-signals-and-matching-pursuit-method
#1
Atefeh Goshvarpour, Ataollah Abbasi, Ateke Goshvarpour
BACKGROUND: The purpose of the current study was to examine the effectiveness of Matching Pursuit (MP) algorithm in emotion recognition. METHODS: Electrocardiogram (ECG) and galvanic skin responses (GSR) of 11 healthy students were collected while subjects were listening to emotional music clips. Applying three dictionaries, including two wavelet packet dictionaries (Coiflet, and Daubechies) and discrete cosine transform, MP coefficients were extracted from ECG and GSR signals...
December 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29433838/preliminary-asian-experience-of-using-perampanel-in-clinical-practice
#2
Hsing-I Chiang, Siew-Na Lim, Hsiang-Yao Hsieh, Mei-Yun Cheng, Chun-Wei Chang, Wei-En Johnny Tseng, Han-Tao Li, Chin-Yin Lin, Tony Wu
BACKGROUND: To analyze the efficacy and safety of perampanel over a 3-month period in a sample of Asian people with epilepsy. METHODS: The efficacy and safety of perampanel as an adjunctive therapy for patients with epilepsy were retrospectively reviewed and analyzed. Patients were categorized according to seizure type, concomitant antiepileptic drug usage, and perampanel dosage. RESULTS: A total of 210 patients were included in the study and 131 patients completed 3 months of perampanel treatment...
December 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29433837/effect-of-enzymatic-pre-treatment-of-microalgae-extracts-on-their-anti-tumor-activity
#3
Asma Jabeen, Brandon Reeder, Soleiman Hisaindee, Salman Ashraf, Naeema Al Darmaki, Sinan Battah, Sulaiman Al-Zuhair
BACKGROUND: There is an increasing need to find natural bioactive compounds for pharmaceutical applications, because they have less harmful side effects compared to their chemical alternatives. Microalgae (MA) have been identified as a promising source for these bioactive compounds, and this work aimed to evaluate the anti-proliferative effects of semi-purified protein extracted from MA against several tumor cell lines. METHODS: Tested samples comprised MA cell extracts treated with cellulase and lysozyme, prior to extraction...
December 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29433836/multiresolution-image-registration-for-multimodal-brain-images-and-fusion-for-better-neurosurgical-planning
#4
Siddeshappa Nandish, Gopalakrishna Prabhu, Kadavigere V Rajagopal
BACKGROUND: Imaging modalities in medicine gives complementary information. Inadequacy in clinical information made single imaging modality insufficient. There is a need for computer-based system that permits rapid acquisition of digital medical images and performs multi-modality registration, segmentation and three-dimensional planning of minimally invasive neurosurgical procedures. In this regard proposed article presents multimodal brain image registration and fusion for better neurosurgical planning...
December 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29433835/towards-automated-detection-semi-quantification-and-identification-of-microbial-growth-in-clinical-bacteriology-a-proof-of-concept
#5
Antony Croxatto, Raphaël Marcelpoil, Cédrick Orny, Didier Morel, Guy Prod'hom, Gilbert Greub
BACKGROUND: Automation in microbiology laboratories impacts management, workflow, productivity and quality. Further improvements will be driven by the development of intelligent image analysis allowing automated detection of microbial growth, release of sterile samples, identification and quantification of bacterial colonies and reading of AST disk diffusion assays. We investigated the potential benefit of intelligent imaging analysis by developing algorithms allowing automated detection, semi-quantification and identification of bacterial colonies...
December 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29433834/gasdermin-a-new-player-to-the-inflammasome-game
#6
Erivan S Ramos-Junior, Ana Carolina Morandini
Pyroptosis is a lytic type of programmed cell death that was traditionally associated with the involvement of inflammatory caspases, such as caspase-1. These inflammatory caspases are activated within multi-protein complexes called inflammasomes that are assembled in response to invading pathogens and/or danger signals. Pyroptotic cell death was suggested to evolve via the formation of pores in the plasma membrane, but the exact mechanism underlying the formation of these pores remained unclear. Recently, gasdermin D, a member of the gasdermin protein family was identified as a caspase substrate and essential effector of pyroptosis, being identified as the protagonist of membrane pore formation...
December 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29433833/macrophage-phagocytosis-cracking-the-defect-code-in-copd
#7
REVIEW
Jamil Jubrail, Nisha Kurian, Florence Niedergang
In the normal non-diseased lung, various macrophage populations maintain homeostasis and sterility by ingesting and clearing inhaled particulates, pathogens and apoptotic cells from the local environment. This process of phagocytosis leads to the degradation of the internalized material, coordinated induction of gene expression, antigen presentation and cytokine production, implicating phagocytosis as a central regulator of innate immunity. Phagocytosis is extremely efficient and any perturbation of this function is deleterious...
December 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29433832/microbes-are-off-the-menu-defective-macrophage-phagocytosis-in-copd
#8
EDITORIAL
Emma Louise Walton
In this issue of the Biomedical Journal, we learn about the pathophysiology of chronic obstructive pulmonary disease and how defective macrophage phagocytosis may lead to the build up of microbes and pollutants in inflamed lungs. We also focus on new findings that may take us a step closer to full automation in diagnostic bacteriology laboratories. Finally, we highlight the anti-tumor properties of microalgae and the application of algorithms to predict human emotion from electrocardiogram.
December 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29179885/bilaterality-of-ovarian-endometriomas-does-not-affect-the-outcome-of-in%C3%A2-vitro-fertilization-intracytoplasmic-sperm-injection-in-infertile-women-after-laparoscopic-cystectomy
#9
Hsing-Tse Yu, Hong-Yuan Huang, Hsiao-Jung Tseng, Chin-Jung Wang, Chyi-Long Lee, Yung-Kuei Soong
BACKGROUND: To assess whether the unilateral or bilateral lesions can affect ovarian reserve and pregnancy outcome in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) in infertility patients underwent laparoscopic cystectomy. METHODS: A total of 148 IVF/ICSI cycle in patients who had undergone laparoscopic cystectomy for unilateral or bilateral endometriomas were reviewed retrospectively. There were 103 cycles where laparoscopic cystectomy had been carried out for unilateral endometriomas and 45 cycles after bilateral-side surgery...
October 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29179884/mortality-pattern-in-otorhinolaryngology-ward-a-5-years%C3%A2-retrospective-study-at-an-urban-tertiary-health-care-center-in-india
#10
Vivek Kumar, Satish Kumar, Naresh Chandra Sharma, Badal Kumar
BACKGROUND: To recognize deaths in the otorhinolaryngology indoor wards, determine the reason behind the mortalities and recommend modifications for betterment of patient care and surgical outcomes. METHOD: Data was collected from the mortality register, operation theatre registers, ward registers and case notes of patients declared dead at an urban tertiary health care center in India for a period of 5 years; from January 2012 to December 2016. The data included date of admission, age, sex, educational status, residence, and clinical diagnosis, course of hospital stay and medical cause of death...
October 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29179883/shifting-trend-of-tubercular-lymphadenitis-over-a%C3%A2-decade-a-study-from-eastern-region-of-india
#11
Senjuti Dasgupta, Sudipta Chakrabarti, Supriya Sarkar
BACKGROUND: The incidence of tuberculosis (TB) is changing in India. The commonest extra pulmonary manifestation of TB is tuberculous lymphadenitis. AIMS AND OBJECTIVES: To detect changes in occurrence of TB lymphadenitis by comparing current data with that from 10 years back. METHODS: Fine Needle Aspiration Cytology (FNAC) findings of patients presenting with lymphadenopathy between January 2014 and December 2015 were included in the study as current data...
October 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29179882/probiotic-potential-of-lactobacilli-with-antagonistic-activity-against-pathogenic-strains-an-in-vitro-validation-for-the-production-of-inhibitory-substances
#12
Chidre Prabhurajeshwar, Revanasiddappa Kelmani Chandrakanth
BACKGROUND: Probiotics, live cells with different beneficiary characteristics, have been extensively studied and explored commercially in many different products in the world. Their benefits to human and animal health have proven in hundreds of scientific studies. Based on rich bibliographic material, Curd is the potential source of probiotic Lactobacilli. METHOD: The aim of the present study was to observe Lactobacilli with probiotic potential activities from different curd samples for isolation, identification and characterization of Lactobacillus species...
October 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29179881/chang-gung-research-database-a-multi-institutional-database-consisting-of-original-medical-records
#13
Ming-Shao Tsai, Meng-Hung Lin, Chuan-Pin Lee, Yao-Hsu Yang, Wen-Cheng Chen, Geng-He Chang, Yao-Te Tsai, Pau-Chung Chen, Ying-Huang Tsai
BACKGROUND: The Chang Gung Research Database (CGRD) is a de-identified database derived from original medical records of Chang Gung Memorial Hospital (CGMH), which comprises seven medical institutes located from the northeast to southern regions of Taiwan. The volume of medical services performed in CGMH is large, and clinical and scientific studies based on the CGRD are reported to be of high quality. However, the CGRD as a useful database for research has not been analyzed before. The objective of the study was to analyze the CGRD with regard to its characteristics and coverage of Taiwan's population...
October 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29179880/the-etiology-of-oxidative-stress-in-insulin-resistance
#14
Samantha Hurrle, Walter H Hsu
Insulin resistance is a prevalent syndrome in developed as well as developing countries. It is the predisposing factor for type 2 diabetes mellitus, the most common end stage development of metabolic syndrome in the United States. Previously, studies investigating type 2 diabetes have focused on beta cell dysfunction in the pancreas and insulin resistance, and developing ways to correct these dysfunctions. However, in recent years, there has been a profound interest in the role that oxidative stress in the peripheral tissues plays to induce insulin resistance...
October 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29179879/p2x4-a-fast-and-sensitive-purinergic-receptor
#15
REVIEW
Jaanus Suurväli, Pierre Boudinot, Jean Kanellopoulos, Sirje Rüütel Boudinot
Extracellular nucleotides have been recognized as important mediators of activation, triggering multiple responses via plasma membrane receptors known as P2 receptors. P2 receptors comprise P2X ionotropic receptors and G protein-coupled P2Y receptors. P2X receptors are expressed in many tissues, where they are involved in a number of functions including synaptic transmission, muscle contraction, platelet aggregation, inflammation, macrophage activation, differentiation and proliferation, neuropathic and inflammatory pain...
October 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29179878/oxidative-stress-and-diabetes-glucose-response-in-the-crossfire
#16
EDITORIAL
Emma Louise Walton
In this issue of the Biomedical Journal, we discuss the emerging role of reactive oxygen species (ROS) in the development of insulin resistance and ultimately type 2 diabetes. We focus also on research investigating the outcome of in vitro fertilization after laproscopic surgery for ovarian endometriosis. Finally, we learn the results of a study on the hunt for new probiotic bacteria.
October 2017: Biomedical Journal
https://www.readbyqxmd.com/read/28918913/understanding-the-dr-jekyll-and-mr-hyde-nature-of-apoptosis-inducing-factor-future-perspectives
#17
LETTER
Giulio Preta
Apoptosis-inducing factor (AIF) is emerging as a key protein in regulation of basic physiological processes including phagocytosis, mitophagy and regulation of the redox state. Recent evidences suggest that the enzymatic activity of AIF may play an active role in tumor progression controlling energy metabolism and redox balance. The present manuscript briefly describes the story of this protein from its initial discovery as caspase-independent apoptotic protein, throughout its role in oxidative phosphorylation and lately involvement in tumor progression...
August 2017: Biomedical Journal
https://www.readbyqxmd.com/read/28918912/evaluation-of-the-root-and-canal-systems-of%C3%A2-maxillary-molars-in-taiwanese-patients-a%C3%A2-cone%C3%A2-beam-computed-tomography-study
#18
Yu-Hua Lin, Hsiu-Na Lin, Chien-Chih Chen, May-Show Chen
BACKGROUND: This study evaluated variations in root canal configuration in the maxillary permanent molars of Taiwanese patients by analyzing patients' cone beam computed tomography (CBCT) images. Comparisons were made among these configurations and those previously reported. This information may serve as a basis for improving the success rate of endodontic treatment. METHODS: The root canal systems of 114 Taiwanese patients with bilateral maxillary first or second molars were examined using CBCT images...
August 2017: Biomedical Journal
https://www.readbyqxmd.com/read/28918911/mortality-of-severe-septic-patients-between-physician-s-high-and-low-care-volumes
#19
Chun-Yao Lin, Jo-Chi Tseng, Chih-Yu Huang, Chien-Ming Chu, Huang-Pin Wu
BACKGROUND: Patients with severe sepsis frequently require intensive care unit (ICU) admission and different ICU care models may influence their outcomes. The mortality of severe septic patients between physician's high and low care volume remains unclear. METHODS: We analyzed the data from a three-year prospective observation study, which was performed in an adult medical ICU of Chung Gung Memorial Hospital, Keelung. The data included initial bundle therapies based on the Surviving Sepsis Campaign (SSC) guidelines for patients with severe sepsis...
August 2017: Biomedical Journal
https://www.readbyqxmd.com/read/28918910/pet-and-mri-image-fusion-based-on-combination-of-2-d-hilbert-transform-and-ihs-method
#20
Mozhdeh Haddadpour, Sabalan Daneshavar, Hadi Seyedarabi
BACKGROUND: The process of medical image fusion is combining two or more medical images such as Magnetic Resonance Image (MRI) and Positron Emission Tomography (PET) and mapping them to a single image as fused image. So purpose of our study is assisting physicians to diagnose and treat the diseases in the least of the time. METHODS: We used Magnetic Resonance Image (MRI) and Positron Emission Tomography (PET) as input images, so fused them based on combination of two dimensional Hilbert transform (2-D HT) and Intensity Hue Saturation (IHS) method...
August 2017: Biomedical Journal
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