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Ophthalmic Surgery, Lasers & Imaging Retina

Aditya Modi, Ruchir A Mehta, Naresh Kumar Yadav
This case report aims to study active cone regeneration and its functional correlation in optic disc pit maculopathy (ODPM) with a large outer macular defect treated with autologous internal limiting membrane (ILM) "chunk" transplantation. Outcome analysis was done using spectral-domain optical coherence tomography (SD-OCT), adaptive optics, and microperimetry. Visual acuity improved from counting fingers at 2 meters to 6/18 Snellen equivalent postoperatively, whereas SD-OCT demonstrated closure of outer subfoveal defect...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Swarup S Swaminathan, Fang Zheng, Andrew R Miller, Giovanni Gregori, Janet L Davis, Philip J Rosenfeld
A 30-year-old woman with photopsias and decreased vision was diagnosed with multiple evanescent white dot syndrome (MEWDS) with an atypical inflammatory subfoveal retinal pigment epithelial detachment (PED) and imaged using swept-source optical coherence tomography (SS-OCT) during several visits. SS-OCT imaging revealed a focal area of attenuated choriocapillaris underneath the PED. An attempt to treat the presumed macular inflammatory lesion with corticosteroids resulted in bilateral exudation consistent with central serous chorioretinopathy...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Brandon Menke, Alex Walters, John F Payne
An 11-year-old boy presented for central vision blurring in each eye. Visual acuity was 20/80 and examination revealed spoke-wheel foveal schisis and peripheral elevated diaphanous inner retina in each eye. Spectral-domain optical coherence tomography showed inner-retinal, flat-topped cysts in each eye. Electrophysiologic testing was refused, but a clinical diagnosis of X-linked retinoschisis was made. Three months after topical dorzolamide (Trusopt; Santen Pharmaceutical, Osaka, Japan) was started, the macular cysts worsened significantly...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Swarup S Swaminathan, Parth Shah, Fang Zheng, Giovanni Gregori, Philip J Rosenfeld
A patient previously diagnosed with Alport Syndrome was evaluated using multimodal imaging. Optical coherence tomography (OCT) demonstrated significant thinning of the inner retina within the macula, and inner retinal cysts were found in the peripheral macula. OCT angiography demonstrated loss of the choriocapillaris. Abnormal collagen appears to have multiple deleterious effects on the retinal and choroidal structure and vasculature. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:138-141.].
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Adam R Sweeney, Qinqin Zhang, Ruikang K Wang, Kasra A Rezaei
Optical coherence tomography angiography (OCTA) is a new imaging technology capable of providing three-dimensional (3-D) retinal and choroidal microvascular maps without a need for exogenous dye. In this study, the authors evaluate the retinal and choroidal microvascular architecture of the macula in a patient with choroidal hemangioma using OCTA. Widefield OCTA with tracking capability and segmentation was performed to provide images with a field of view at 9 × 9 mm2. The en face maximum projection was used to generate 2-D angiograms of different layers with color-coded images...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Avni P Finn, Lejla Vajzovic
BACKGROUND AND OBJECTIVE: As an increasing number of vitreoretinal surgeons are implanting retinal prosthesis devices, the need to share surgical techniques to ease implantation in challenging scenarios grows. The authors share a technique to aide in overcoming a challenge associated with uveal prolapse in a patient undergoing Argus II retinal prosthesis (Second Sight Medical Products, Sylmar, CA) implantation. PATIENTS AND METHODS: A surgical technique is discussed and demonstrated using a video (Video available at www...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Tiffany A Chen, Ira H Schachar, Darius M Moshfeghi
BACKGROUND AND OBJECTIVE: To investigate the outcomes of infants with treatment-warranted retinopathy of prematurity (TW-ROP) who received intravitreal bevacizumab (Avastin; Genentech, South San Francisco, CA) (IVB) injections as compared to diode laser photocoagulation (DLP). PATIENTS AND METHODS: Data from the Stanford University Network for Diagnosis of Retinopathy of Prematurity database and inpatients at Stanford Children's Hospital were retrospectively reviewed for premature newborns with TW-ROP treated with DLP or 0...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Khalil Ghasemi Falavarjani, David Sarraf, Irena Tsui
BACKGROUND AND OBJECTIVE: To evaluate the fovea microvasculature in adult subjects with history of preterm birth using optical coherence angiography (OCTA). PATIENTS AND METHODS: In this retrospective study, macular OCTA images were obtained from adult subjects with a history of preterm birth. The presence of the foveal avascular zone (FAZ) and its size was determined. RESULTS: Ten eyes from six subjects with ages ranging from 26 years old to 65 years old were evaluated...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Zofia Michalewska, Jerzy Nawrocki
BACKGROUND AND OBJECTIVE: To evaluate swept-source optical coherence tomography angiography (SS-OCTA) images in full-thickness macular holes (FTMHs). PATIENTS AND METHODS: SS-OCTA of FTMHs was performed before or after surgery. Vitrectomy with the temporal inverted internal limiting membrane flap technique was used. The authors measured the diameter and area of the foveal avascular zone (FAZ) in superficial and deep retina vasculature. RESULTS: In 88 patients, two artifact types were observed...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Cassie A Ludwig, Natalia F Callaway, Mark S Blumenkranz, Douglas R Fredrick, Darius M Moshfeghi
BACKGROUND AND OBJECTIVE: The validity of the red reflex exam has yet to be tested against new methods of wide-angle imaging that may improve early detection of neonatal ocular pathology. The authors aimed to determine the validity of the pediatrician's red reflex exam using 130° wide-angle external and fundus digital imaging as a gold standard. PATIENTS AND METHODS: This was a prospective cohort study of 194 healthy, term newborns enrolled in the Newborn Eye Screening Test study at Lucile Packard Children's Hospital from July 25, 2013, to July 25, 2014...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Chen D Lu, Nadia K Waheed, Andre Witkin, Caroline R Baumal, Jonathan J Liu, Benjamin Potsaid, Anthony Joseph, Vijaysekhar Jayaraman, Alex Cable, Kinpui Chan, Jay S Duker, James G Fujimoto
BACKGROUND AND OBJECTIVE: To demonstrate the feasibility of retinal and anterior segment intraoperative widefield imaging using an ultrahigh-speed, swept-source optical coherence tomography (SS-OCT) surgical microscope attachment. PATIENTS AND METHODS: A prototype post-objective SS-OCT using a 1,050-nm wavelength, 400 kHz A-scan rate, vertical cavity surface-emitting laser (VCSEL) light source was integrated to a commercial ophthalmic surgical microscope after the objective...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Katja Hatz, Frank Zimmermann, Dimitrios Kardamakis, Emmanouil Lazaridis, Cengiz Türksever, Jörg Binder, Alexandros Papachristofilou, Christian Prünte
BACKGROUND AND OBJECTIVE: To evaluate the effectiveness and safety of low-energy stereotactic radiotherapy (SRT) combined with anti-vascular endothelial growth factor (VEGF) treatment following a treat-and-extend regimen (TER) in wet age-related macular degeneration (AMD). PATIENTS AND METHODS: Before/after SRT, the authors compared retrospective consecutive case series of 50 patients requiring frequent anti-VEGF treatment (every 4 or 6 weeks) in wet AMD, treated with a single session of SRT and TER (same manner pre/post-SRT)...
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Sidney Schechet, Seenu M Hariprasad, Asadolah Movahedan, Dimitra Skondra
No abstract text is available yet for this article.
February 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Heloisa Nascimento, Jacqueline M Sousa, Délia González Fernández, Gustavo H A Salomão, Elcio H Sato, Cristina Muccioli, Rubens Belfort
In a prospective case series of patients with Blau-Jabs syndrome (BJS) conducted in the Ophthalmology Department/Federal University of Sao Paulo, seven patients with clinical and ophthalmologic manifestations of the disease and a positive genetic test result for the presence of a mutation in the CARD15/NOD2 gene were followed for a minimal period of 1 year. All patients had uveitis, five had nummular corneal subepithelial opacities, and four had multifocal choroiditis. Oral prednisolone was administered to all patients; inflammation was controlled in six patients with at least one immunosuppressive drug...
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Sevil Ari Yaylali, Nedim Bromand, Guler Kilic
The authors report a new spectral-domain optical coherence tomography (SD-OCT) appearance observed in two patients with Purtscher-like retinopathy. In this prospective case series of three eyes of two patients with Purtscher-like retinopathy, the patients were assessed with biomicroscopy, fluorescein angiography (FA), and SD-OCT. The last examinations of the patients were performed at 3 months and 12 months, respectively. Both patients presented with decreased visual acuity. Fundus examination revealed a whitish-appearing parafoveal retina and scattered cotton-wool spots in the posterior retina...
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Ravi Sharma, Sandeep Randhawa
A 12-year-old Indian boy presented with acute and severe vision loss in his right eye. He was being treated for scalp alopecia areata and rashes behind the ears and above the brow. The eye examination revealed unilateral hemorrhagic retinal vasculitis. The lab work was normal except for a positive HLA-B27 result. The patient was treated with intravitreal bevacizumab (Avastin; Genentech, South San Francisco, CA) and systemic immunosuppression. The retinal vasculitis improved with treatment, but visual acuity only mildly improved...
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Dilek Güven, Mehmet Demir, Delil Özcan, Hakan Kaçar, Semra Tiryaki Demir, Saniye Üke Uzun
A 58-year-old man with end-stage retinitis pigmentosa (RP) and visual acuity of light perception in both eyes received simultaneous phacoemulsification with intraocular lens implantation and implantation of the Argus II Retinal Prosthesis System (Second Sight Medical Products, Sylmar, CA) to his right eye 1 year ago. He accomplished the fitting and rehabilitation sessions, and no extraocular or intraocular complications were encountered perioperatively, postoperatively, or during the follow-up. The patient used the prosthesis actively for 2...
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Ismini Koulouri, Eric D Gaier, Dean Eliott, Demetrios G Vavvas
A rare case of a woman in her thirties with double optic disc pits involving opposing sectors is reported. Significantly decreased vision due to macular schisis was noted. Wide-field optical coherence tomography revealed distinct laminar defects and glial tufts associated with each pit. This case illustrates a rare view into the pathogenesis of optic disc pits. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:52-54.].
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Ali Dirani, Marina Ravagnani Ciongoli, Mark R Lesk, Flavio Rezende
BACKGROUND AND OBJECTIVE: Pars plana glaucoma drainage implant (GDI) occlusion is mainly related to entrapment of residual anterior vitreous gel in the implant. The aim of the present report is to describe a new surgical technique to induce pneumatic anterior hyaloid detachment in eyes with GDI. PATIENTS AND METHODS: This is a description of the surgical technique used to induce pneumatic anterior hyaloid detachment. RESULTS: The technique was used in two cases...
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Yasin Sakir Goker, Kemal Yuksel, Miray Faiz Turan, Kenan Sonmez, Kemal Tekin, Pelin Yilmazbas
BACKGROUND AND OBJECTIVE: To determine possible changes in thickness profiles of retinal layers in patients with rhegmatogenous retinal detachment (RRD) treated with perfluoropropane (C3F8) or silicon oil (SiO). PATIENTS AND METHODS: Seventy-two eyes of 36 patients were enrolled in this retrospective comparative study. Patients were divided into two groups according to intraocular tamponade: C3F8 or SiO. All study eyes were compared with fellow eyes via spectral-domain optical coherence tomography segment analysis at 6 months postoperatively...
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
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