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Ophthalmic Surgery, Lasers & Imaging Retina

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https://www.readbyqxmd.com/read/28195625/8-questions-with-dr-moshfeghi
#1
Scott Cousins, Darius M Moshfeghi
No abstract text is available yet for this article.
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195624/spontaneous-closure-of-full-thickness-macular-hole-with-epiretinal-membrane-in-vitrectomized-eyes-case-series-and-review-of-literature
#2
Wenlan Zhang, Dilraj S Grewal, Glenn J Jaffe, Tamer H Mahmoud, Sharon Fekrat
The authors describe three vitrectomized eyes that each subsequently developed a full-thickness macular hole (FTMH) that then spontaneously closed and summarize the current literature reporting these rare events. Clinical history, imaging, and course of three patients were reviewed and compiled. All three cases in this series developed a FTMH less than 7 months following vitrectomy (for epiretinal membrane [ERM], n = 1) and retinal detachment (n = 2) that demonstrated spontaneous resolution within 2 months of symptom onset, without intervention...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195623/internal-limiting-membrane-peeling-by-23-gauge-endoscopy-for-macular-hole-retinal-detachment-in-a-pathological-myopic-eye
#3
Yiqi Chen, Lijun Shen, Shixin Zhao, Lin Wang, Changbiao Xu
Endoscopic vitrectomy can uniquely circumvent anterior segment opacities and is applied to a wide spectrum of retina diseases with media opacities. However, endoscopic internal limiting membrane (ILM) peeling has not been described. The authors present one case of a retinal detachment caused by a macular hole in a pathological myopic eye combined with severe keratoleukoma. The 1-year outcome after 23-gauge endoscopic ILM peeling was good. This case report demonstrates that ILM peeling with a 23-gauge endoscope, which requires subtle and difficult macular manipulation, is feasible and effectively treats macular holes complicated with anterior segment opacities...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195622/optical-coherence-tomography-angiography-of-paracentral-acute-middle-maculopathy-associated-with-primary-antiphospholipid-syndrome
#4
Matthew G J Trese, Aristomenis Thanos, Yoshihiro Yonekawa, Sandeep Randhawa
The authors present the first case of paracentral acute middle maculopathy as a manifestation of primary antiphospholipid syndrome (APS) with multimodal imaging, including optical coherence tomography angiography (OCTA). The association between APS and ophthalmic sequela is well-known. Recent advances in multimodal imaging, specifically OCTA, allow for better characterization of the mechanism and extent by which retinal arterial thrombosis can cause vision loss. Using advanced imaging modalities, the authors provide a comprehensive assessment of retinal ischemia, which showed not only localized capillary occlusion, but also ischemia of the deep retinal capillary plexus...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195621/histopathologic-analysis-of-the-posterior-segment-for-terson-s-syndrome-the-giobiopsy-technique
#5
Jerome V Giovinazzo, Vincent J Giovinazzo, Codrin Iacob, Richard B Rosen, Paul T Finger
The purpose of this study was to report on a case of Terson's syndrome (TS) using a novel instrument and technique to harvest posterior pole pathology from a postmortem eye. A modified ocular clamp was used to remove the posterior pole from the postmortem enucleated eye. Gross photographs were taken and an ocular sample of the posterior pole was sent to The New York Eye and Ear Pathology Laboratory. TS was identified from gross pathology and histologic examinations. The case history was consistent with that diagnosis...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195619/efficacy-of-the-intravitreal-sustained-release-dexamethasone-implant-for-diabetic-macular-edema-refractory-to-anti-vascular-endothelial-growth-factor-therapy-meta-analysis-and-clinical-implications
#6
Zainab Khan, Robin K Kuriakose, Maryam Khan, Eric K Chin, David R P Almeida
BACKGROUND AND OBJECTIVE: To assess the effect on best-corrected visual acuity (BCVA) and efficacy of the intravitreal sustained-release 0.7 mg dexamethasone implant (Ozurdex; Allergan, Irvine, CA) in patients with recalcitrant diabetic macular edema (DME). PATIENTS AND METHODS: Meta-analysis utilizing the MOOSE framework and a random effects model. Studies included adults undergoing treatment with Ozurdex for DME. The methodologic quality of each study was assessed using the MINORS and the Cochrane Collaboration Risk of Bias for randomized studies...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195618/preclinical-acute-ocular-safety-study-of-combined-intravitreal-carboplatin-and-etoposide-phosphate-for-retinoblastoma
#7
Brian G Mohney, Victor M Elner, Andrew B Smith, J William Harbour, Brian D Smith, David C Musch, Stephen J Smith
BACKGROUND AND OBJECTIVE: To describe the ocular toxicity of intravitreal carboplatin and etoposide phosphate (VP16P) in Dutch-Belted rabbits. MATERIALS AND METHODS: Twenty-two adult male Dutch-Belted rabbits (Cohort 1) each received a single, bilateral intravitreal injection (0.05 mL). For Cohort 1, safety was assessed via electroretinograms (ERGs) and ocular examination. Of nine total groups in Cohort 1, the first five received the following single agents: Group 1: normal saline; Group 2: VP16P 75 µg; Group 3: VP16P 100 µg; Group 4: carboplatin 4 µg; and Group 5: carboplatin 8 µg...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195617/pediatric-traumatic-retinal-detachments-clinical-characteristics-and-outcomes
#8
Sabahattin Sul, Gökhan Gurelik, Safak Korkmaz, Sengül Ozdek, Berati Hasanreisoglu
BACKGROUND AND OBJECTIVE: To compare clinical characteristics and surgical outcomes of retinal detachment (RD) after open globe injuries (OGIs) and closed globe injuries (CGIs). PATIENTS AND METHODS: One hundred ten eyes of 110 patients aged 17 years or younger who underwent primary RD repair after OGI and CGI between 2010 and 2013 were reviewed retrospectively. RESULTS: Cataract (59.8% vs. 21.7%; P = .002) and vitreous hemorrhage (54% vs...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195616/clinical-features-and-management-of-subretinal-abscesses-secondary-to-methicillin-resistant-staphylococcus-aureus-endogenous-endophthalmitis
#9
Jorge Fortun, Yasha S Modi, Angela Bessette, Jordan Heffez, Petros Carvounis, Daniel S Petkovsek, Nicholas G Anderson, Daniel Martin, Sunil Srivastava
BACKGROUND AND OBJECTIVE: To describe the clinical features, management, and immediate outcomes of patients with subretinal abscesses secondary to methicillin-resistant Staphylococcus aureus (MRSA) endogenous endophthalmitis. PATIENTS AND METHODS: Eleven eyes of seven patients were identified by retrospective chart review. Demographics, initial presentation, examination findings, imaging, cultures, treatments, and short-term outcomes were reviewed. RESULTS: Eleven eyes of seven patients presented with subretinal abscesses secondary to MRSA endogenous endophthalmitis...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195615/quantitative-analysis-of-en-face-spectral-domain-optical-coherence-tomography-imaging-in-polypoidal-choroidal-vasculopathy
#10
Joseph M Simonett, Errol W Chan, Jonathan Chou, Dimitra Skondra, Daniel Colon, Caroline K Chee, Gopal Lingam, Amani A Fawzi
BACKGROUND AND OBJECTIVE: Spectral-domain optical coherence tomography (SD-OCT) imaging can be used to visualize polypoidal choroidal vasculopathy (PCV) lesions in the en face plane. Here, the authors describe a novel lesion quantification technique and compare PCV lesion area measurements and morphology before and after anti-vascular endothelial growth factor (VEGF) treatment. PATIENTS AND METHODS: Volumetric SD-OCT scans in eyes with PCV before and after induction anti-VEGF therapy were retrospectively analyzed...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195614/omega-sign-a-distinct-optical-coherence-tomography-finding-in-macular-combined-hamartoma-of-retina-and-retinal-pigment-epithelium
#11
Vinod Kumar, Rohan Chawla, Koushik Tripathy
BACKGROUND AND OBJECTIVE: To report a distinct optical coherence tomography (OCT) appearance of macular combined hamartoma of retina and retinal pigment epithelium (CHRRPE). PATIENTS AND METHODS: This is a retrospective case series of four eyes of four patients with macular CHRRPE who were assessed with the help of color fundus photographs, swept-source OCT (SS-OCT), and fundus fluorescein angiography wherever required. RESULTS: All four patients presented with decreased visual acuity...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195613/functional-and-morphological-evaluation-of-traumatized-eyes-with-berlin-s-edema-affecting-the-macula-using-mferg-microperimetry-and-sd-oct
#12
Joseph Daniel Boss, Joaquin Tosi, Inna Glybina, Asheesh Tewari, Gary W Abrams
BACKGROUND AND OBJECTIVE: To describe the structural and functional changes that occur in traumatic Berlin's edema involving the macula through assessment with multifocal electroretinogram (mfERG), microperimetry, fundus photography, and spectral-domain optical coherence tomography (SD-OCT). PATIENTS AND METHODS: Retrospective case series of five eyes from four patients with macular traumatic Berlin's edema. Patients underwent baseline mfERG (three eyes), MP1 microperimetry (three eyes), fundus photography (five eyes), and SD-OCT (five eyes)...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195612/relationships-between-spatial-contrast-sensitivity-and-parafoveal-cone-density-in-normal-subjects-and-patients-with-retinal-degeneration
#13
Masakazu Hirota, Takeshi Morimoto, Hiroyuki Kanda, Tibor Karl Lohmann, Suguru Miyagawa, Takao Endo, Tomomitsu Miyoshi, Takashi Fujikado
BACKGROUND AND OBJECTIVE: To investigate the relationship between spatial contrast sensitivity (CS) and parafoveal cone density (PCD). PATIENTS AND METHODS: Fifteen healthy individuals (mean age: 26.1 years ± 4.5 years) and nine patients with hereditary retinal degeneration (mean age: 31.6 years ± 13.4 years) without media opacities were studied. The CS was measured by CSV-1000 (VectorVision, Greenville, OH). The cone mosaic was photographed with an adaptive optics scanning laser ophthalmoscope (AOSLO) with a 1° × 1° field of view centered on the fovea...
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195611/an-overview-of-the-fovista-and-rinucumab-trials-and-the-fate-of-anti-pdgf-medications
#14
Evan N Dunn, Seenu M Hariprasad, Veeral S Sheth
No abstract text is available yet for this article.
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195610/hydroxychloroquine-screening-alert-change-is-in-the-wind
#15
EDITORIAL
Michael F Marmor
Recent studies have changed the management of hydroxychloroquine retinopathy. This editorial outlines a new standard. Estimate dose by real weight, staying below 5 mg/kg. Asian patients may show initial damage outside the parafovea. Renal disease, maculopathy, and tamoxifen are major risk factors. Proper screening allows long usage and avoids bull's eye retinopathy.
February 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28195620/significant-bilateral-response-in-diabetic-macular-edema-after-single-unilateral-intravitreal-aflibercept-injection
#16
Ehsan Rahimy, Omondi Nyong'o, Theodore Leng
A 61-year-old patient with bilateral, treatment-naïve, diffuse diabetic macular edema (DME) that had been progressing during the previous 12 months received a single intravitreal injection of aflibercept (Eylea; Regeneron, Tarrytown, NY) to the left eye. At 2-week follow-up, noticeable bilateral improvement of the DME was observed by spectral-domain optical coherence tomography imaging with commensurate improvement of visual acuity to 20/30 bilaterally. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:167-169...
1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28060402/8-questions-with-darius-moshfeghi
#17
Justis P Ehlers, Darius M Moshfeghi
No abstract text is available yet for this article.
January 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28060401/choroidal-osteoma-deossification-visualized-by-enhanced-depth-imaging-spectral-domain-optical-coherence-tomography
#18
Meleha Ahmad, Edmund Tsui, R Theodore Smith
Choroidal osteoma (CO) is a rare, benign ossifying lesion of the choroid found in otherwise healthy patients. Although associated with good visual prognosis, tumor deossification in choroidal osteoma has been linked with vision loss, presumably due to overlying photoreceptor degeneration. Here the authors present a case of CO in an elderly male demonstrating tumor deossification and photoreceptor atrophy during a 3-year follow-up using enhanced depth imaging optical coherence tomography (EDI-OCT). Visual acuity was maintained due to the tumor's noncentral location...
January 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28060400/retinal-detachment-in-a-combined-case-of-stickler-syndrome-and-x-linked-retinoschisis
#19
Neesurg S Mehta, Nicolas A Yannuzzi, Ryan Young, Andrew J McClellan, Sarah P Read, Audina M Berrocal
A 12-year-old boy presented with a total rhegmatogenous retinal detachment and a giant retinal tear in the right eye. Clinical examination, optical coherence tomography, and fundus images showed an optically empty vitreous, lattice degeneration, and retinoschisis of the macula. Genetic testing revealed mutations in the COL2A1 and RS1 genes, confirming a dual diagnosis of Stickler syndrome and X-linked retinoschisis, respectively. This represents the first published account of a patient with both Stickler syndrome and X-linked retinoschisis...
January 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28060399/are-multiple-retinal-arterial-macroaneurysms-considered-a-sign-of-cerebral-aneurysms
#20
Serhad Nalcaci, Zafer Oztas, Cenk Eraslan, Cezmi Akkin
The aim of this study is to report the coexistence of retinal arterial macroaneurysms (RAMs) and cerebral aneurysms (CAs) in a 58-year-old woman with hypertension. She was noted as having a 1-week history of vision loss in her left eye, along with a 2-month history of a nonspecific headache. Visual acuity was 20/32 in her left eye and 20/20 in her right eye. A fundus examination revealed multiple areas of retinal hemorrhages that were surrounded by circinate exudation in her left eye, as well as the generalized attenuation of the retinal arteries in both of her eyes...
January 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
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