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JACC. Heart Failure

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https://www.readbyqxmd.com/read/28711448/the-paradox-in-demonstrating-hydralazine-nitrate-efficacy
#1
EDITORIAL
Jay N Cohn
No abstract text is available yet for this article.
July 7, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28711451/atrial-fibrillation-in-heart-failure-with-preserved-mid-range-and-reduced-ejection-fraction
#2
Ulrik Sartipy, Ulf Dahlström, Michael Fu, Lars H Lund
OBJECTIVES: The study sought to assess the independent risk factors for, consequences of, and outcomes with atrial fibrillation (AF) compared with sinus rhythm (SR) in heart failure (HF) with preserved ejection fraction (HFpEF) versus HF with mid-range ejection fraction (HFmrEF) versus HF with reduced ejection fraction (HFrEF). BACKGROUND: AF is common in HF, but most data are from HFrEF. The importance of AF in HFpEF and MFmrEF is less well known. METHODS: In patients from 2000 to 2012 in the SwedeHF (Swedish Heart Failure Registry) registry, enriched with patient-level data from national health care registries, the authors assessed prevalence of, associations with and prognostic impact of AF in HFpEF versus HFmrEF versus HFrEF...
July 6, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28711450/atrial-fibrillation-in-heart-failure-a%C3%A2-common-and-deadly-combination
#3
EDITORIAL
Carolyn S P Lam, Bernadet T Santema, Adriaan A Voors
No abstract text is available yet for this article.
July 6, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28711449/intrarenal-flow-alterations-during-transition-from-euvolemia-to-intravascular-volume-expansion-in-heart-failure-patients
#4
Petra Nijst, Pieter Martens, Matthias Dupont, W H Wilson Tang, Wilfried Mullens
OBJECTIVES: The goal of this study was to assess: 1) the intrarenal flow in heart failure (HF) patients during the transition from euvolemia to intravascular volume overload; and 2) the relationship between intrarenal flow and diuretic efficiency. BACKGROUND: Intrarenal blood flow alterations may help to better understand impaired volume handling in HF. METHODS: Resistance index (RI) and venous impedance index (VII) were assessed in 6 healthy subjects, 40 euvolemic HF patients with reduced ejection fraction (HFrEF) and 10 HF patients with preserved ejection fraction (HFpEF)...
July 6, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28711447/the-transition-from-hypertension-to%C3%A2-heart%C3%A2-failure-contemporary-update
#5
REVIEW
Franz H Messerli, Stefano F Rimoldi, Sripal Bangalore
Longstanding hypertension ultimately leads to heart failure (HF), and as a consequence most patients with HF have a history of hypertension. Conversely, absence of hypertension in middle age is associated with lower risks for incident HF across the remaining life course. Cardiac remodeling to a predominant pressure overload consists of diastolic dysfunction and concentric left ventricular (LV) hypertrophy. When pressure overload is sustained, diastolic dysfunction progresses, filling of the concentric remodeled LV decreases, and HF with preserved ejection fraction ensues...
July 6, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28711446/clinical-effectiveness-of-hydralazine-isosorbide-dinitrate-in-african-american-patients-with-heart%C3%A2-failure
#6
Boback Ziaeian, Gregg C Fonarow, Paul A Heidenreich
OBJECTIVES: This study sought to evaluate the effectiveness of hydralazine-isosorbide dinitrate (H-ISDN) in African Americans with heart failure (HF) with reduced ejection fraction (HFrEF). BACKGROUND: Among African-American patients with HFrEF, H-ISDN was found to improve quality of life and lower HF-related hospitalization and mortality rates in the A-HEFT (African-American Heart Failure Trial). Few studies have evaluated the effectiveness of this therapy in clinical practice...
July 6, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28711445/the-fastest-way-to-the-failing-heart-is-through-the-kidneys
#7
EDITORIAL
Kevin Damman, Adriaan A Voors
No abstract text is available yet for this article.
July 6, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28624487/the-changing-landscape-of-atrial%C3%A2-fibrillation-time-to-target-heart-failure-prevention
#8
EDITORIAL
Darae Ko, Renate B Schnabel, Ludovic Trinquart, Emelia J Benjamin
No abstract text is available yet for this article.
June 14, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28624484/progression-to-stage-d-heart-failure-among-outpatients-with-stage-c-heart-failure-and-reduced-ejection-fraction
#9
Andreas P Kalogeropoulos, Ayman Samman-Tahhan, Jeffrey S Hedley, Andrew A McCue, Jonathan B Bjork, David W Markham, Kunal N Bhatt, Vasiliki V Georgiopoulou, Andrew L Smith, Javed Butler
OBJECTIVES: This study sought to estimate the rate of progression to Stage D heart failure (HF) among outpatients with Stage C HF and to identify risk factors for progression. BACKGROUND: The pool of patients who may be candidates for advanced HF therapies is growing. METHODS: We estimated 3-year progression to clinically determined Stage D HF and competing mortality among 964 outpatients with Stage C heart failure with reduced ejection fraction (HFrEF), where ejection fraction is ≤40%...
June 14, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28624485/time-to-take-the-failure-out%C3%A2-of%C3%A2-heart%C3%A2-failure-the-importance-of-optimism
#10
EDITORIAL
John G F Cleland, Pierpaolo Pellicori, Andrew L Clark, Mark C Petrie
No abstract text is available yet for this article.
June 1, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28624486/modifiable-risk-factors-for-incident-heart%C3%A2-failure-in-atrial-fibrillation
#11
Neal A Chatterjee, Claudia U Chae, Eunjung Kim, M Vinayaga Moorthy, David Conen, Roopinder K Sandhu, Nancy R Cook, I-Min Lee, Christine M Albert
OBJECTIVES: This study sought to identify modifiable risk factors and estimate the impact of risk factor modification on heart failure (HF) risk in women with new-onset atrial fibrillation (AF). BACKGROUND: Incident HF is the most common nonfatal event in patients with AF, although strategies for HF prevention are lacking. METHODS: We assessed 34,736 participants in the Women's Health Study who were free of prevalent cardiovascular disease at baseline...
May 31, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28624483/biomarker-profiles-of-acute%C3%A2-heart%C3%A2-failure%C3%A2-patients-with-a%C3%A2-mid-range-ejection%C3%A2-fraction
#12
Jasper Tromp, Mohsin A F Khan, Robert J Mentz, Christopher M O'Connor, Marco Metra, Howard C Dittrich, Piotr Ponikowski, John R Teerlink, Gad Cotter, Beth Davison, John G F Cleland, Michael M Givertz, Daniel M Bloomfield, Dirk J van Veldhuisen, Hans L Hillege, Adriaan A Voors, Peter van der Meer
OBJECTIVES: In this study, the authors used biomarker profiles to characterize differences between patients with acute heart failure with a midrange ejection fraction (HFmrEF) and compare them with patients with a reduced (heart failure with a reduced ejection fraction [HFrEF]) and preserved (heart failure with a preserved ejection fraction [HFpEF]) ejection fraction. BACKGROUND: Limited data are available on biomarker profiles in acute HFmrEF. METHODS: A panel of 37 biomarkers from different pathophysiological domains (e...
May 31, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28501521/associations-between-short-or-long-length%C3%A2-of-stay-and-30-day-readmission-and-mortality-in-hospitalized-patients-with-heart%C3%A2-failure
#13
Maneesh Sud, Bing Yu, Harindra C Wijeysundera, Peter C Austin, Dennis T Ko, Juarez Braga, Peter Cram, John A Spertus, Michael Domanski, Douglas S Lee
OBJECTIVES: This study sought to examine the associations between heart failure (HF)-related hospital length of stay and 30-day readmissions and HF hospital length of stay and mortality rates. BACKGROUND: Although reducing HF readmission and mortality rates are health care priorities, how HF-related hospital length of stay affects these outcomes is not fully known. METHODS: A population-level, multicenter cohort study of 58,230 patients with HF (age >65 years) was conducted in Ontario, Canada between April 1, 2003 and March 31, 2012...
May 10, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28501527/race-ethnic-differences-in-outcomes-among-hospitalized-medicare-patients-with-heart-failure-and-preserved-ejection%C3%A2-fraction
#14
Boback Ziaeian, Paul A Heidenreich, Haolin Xu, Adam D DeVore, Roland A Matsouaka, Adrian F Hernandez, Deepak L Bhatt, Clyde W Yancy, Gregg C Fonarow
OBJECTIVES: This study analyzed HFpEF patient characteristics and clinical outcomes according to race/ethnicity and adjusted for patient and hospital characteristics along with socioeconomic status (SES). BACKGROUND: The proportion of hospitalizations for heart failure with preserved ejection fraction (HFpEF) has increased over the last decade. Whether the short- and long-term outcomes differ between racial/ethnic groups is not well described. METHODS: The Get With The Guidelines-Heart Failure registry was linked to Medicare administrative data to identify hospitalized patients with HFpEF ≥65 years of age with left ventricular ejection fraction ≥50% between 2006 and 2014...
May 2, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28501524/holding-the-readmission-gates-incentivizing-quality-and-cost-effective-care-for-heart-failure
#15
EDITORIAL
Gregg C Fonarow, Boback Ziaeian
No abstract text is available yet for this article.
May 2, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28501522/long-term-effects-of-flosequinan-on-the-morbidity-and-mortality-of-patients-with-severe-chronic-heart-failure-primary-results-of-the-profile-trial-after-24-years
#16
Milton Packer, Bertram Pitt, Jean-Lucien Rouleau, Karl Swedberg, David L DeMets, Lloyd Fisher
OBJECTIVES: The objective of this clinical trial was to evaluate the long-term effects of flosequinan on the morbidity and mortality of patients with severe chronic heart failure. BACKGROUND: Flosequinan was the first oral vasodilator to be used in the clinic to augment the effects of digitalis, diuretics, and angiotensin-converting enzyme inhibitors in heart failure. However, the drug activated neurohormonal systems and exerted both positive inotropic and chronotropic effects, raising concerns about its safety during long-term use...
May 2, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28501520/can-heart-failure-with-preserved-ejection%C3%A2-fraction-shed-light-on-the-mortality-readmissions-paradox
#17
EDITORIAL
Jennifer E Ho
No abstract text is available yet for this article.
May 2, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28662939/a-decade-with-editorial%C3%A2-mentors-the-day-they-dropped-the-mic
#18
EDITORIAL
Christopher M O'Connor
No abstract text is available yet for this article.
July 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28662938/intersection-of-2-epidemics-asthma-and-cardiovascular-disease
#19
EDITORIAL
John S Gottdiener
No abstract text is available yet for this article.
July 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28662937/a-history-of-asthma-from-childhood-and%C3%A2-left-ventricular-mass-in-asymptomatic%C3%A2-young-adults-the-bogalusa-heart-study
#20
Dianjianyi Sun, Tiange Wang, Yoriko Heianza, Jun Lv, Liyuan Han, Felicia Rabito, Tanika Kelly, Shengxu Li, Jiang He, Lydia Bazzano, Wei Chen, Lu Qi
OBJECTIVES: This study aimed to examine whether a history of asthma from childhood is associated with left ventricular (LV) mass in adulthood. BACKGROUND: Asthma has been related to various cardiovascular risk factors affecting LV hypertrophy. The authors saw a need for a prospective study to analyze the relationship between a history of asthma from childhood and markers of LV mass among asymptomatic young adults. METHODS: Prospective analyses were performed among 1,118 Bogalusa Heart Study participants (average age at follow-up 36...
July 2017: JACC. Heart Failure
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