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JACC. Heart Failure

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https://www.readbyqxmd.com/read/28396043/body-mass-index-and-cardiorespiratory-fitness-in-mid-life-and-risk-of-heart-failure%C3%A2-hospitalization-in-older-age-findings-from-the-cooper-center-longitudinal-study
#1
Ambarish Pandey, William K Cornwell, Benjamin Willis, Ian J Neeland, Ang Gao, David Leonard, Laura DeFina, Jarett D Berry
OBJECTIVES: This study evaluated the contributions of obesity and changes in body mass index (BMI) in mid-life to long-term heart failure (HF) risk independent of cardiorespiratory fitness (CRF) levels. BACKGROUND: Obesity and low CRF are well-established risk factors for HF. However, given the inverse association between CRF and obesity, the independent contributions of BMI toward HF risk are not fully understood. METHODS: We included 19,485 participants from the Cooper Center Longitudinal Study who survived to receive Medicare coverage, from 1999 to 2009...
March 30, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28396042/promise-of-a-new-role-for-heart-rate-variability-in-the-clinical-management-of-patients-with-heart-failure
#2
EDITORIAL
Philip F Binkley
No abstract text is available yet for this article.
March 30, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28396041/association-of-holter-derived-heart-rate-variability-parameters-with-the-development-of-congestive-heart-failure-in-the-cardiovascular-health-study
#3
Vaiibhav N Patel, Brian R Pierce, Rohan K Bodapati, David L Brown, Diane G Ives, Phyllis K Stein
OBJECTIVES: This study sought to determine whether Holter-based parameters of heart rate variability (HRV) are independently associated with incident heart failure among older adults in the CHS (Cardiovascular Health Study) as evidenced by an improvement in the predictive power of the Health Aging and Body Composition Heart Failure (Health ABC) score. BACKGROUND: Abnormal HRV, a marker of autonomic dysfunction, has been associated with multiple adverse cardiovascular outcomes but not the development of congestive heart failure (CHF)...
March 30, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28396040/risk-assessment-and-comparative-effectiveness-of-left-ventricular-assist-device-and-medical-management-in-ambulatory-heart-failure-patients-the-roadmap-study-2-year-results
#4
Randall C Starling, Jerry D Estep, Douglas A Horstmanshof, Carmelo A Milano, Josef Stehlik, Keyur B Shah, Brian A Bruckner, Sangjin Lee, James W Long, Craig H Selzman, Vigneshwar Kasirajan, Donald C Haas, Andrew J Boyle, Joyce Chuang, David J Farrar, Joseph G Rogers
OBJECTIVES: The authors sought to provide the pre-specified primary endpoint of the ROADMAP (Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients) trial at 2 years. BACKGROUND: The ROADMAP trial was a prospective nonrandomized observational study of 200 patients (97 with a left ventricular assist device [LVAD], 103 on optimal medical management [OMM]) that showed that survival with improved functional status at 1 year was better with LVADs compared with OMM in a patient population of ambulatory New York Heart Association functional class IIIb/IV patients...
March 30, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28396039/therapeutic-cardiorespiratory-fitness-to-prevent-and-treat-heart-failure
#5
EDITORIAL
Carl J Lavie, Steven J Keteyian, Hector O Ventura
No abstract text is available yet for this article.
March 30, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28285120/unraveling-the-relationship-between-aging-and-heart-failure-with-preserved%C3%A2-ejection-fraction-the-importance-of-exercise-and-normative-reference-standards
#6
EDITORIAL
Dalane W Kitzman, Thomas J O'Neill, Peter H Brubaker
No abstract text is available yet for this article.
March 7, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28285119/fitness-in-young-adulthood-and-long-term-cardiac-structure-and-function-the-cardia-study
#7
Ambarish Pandey, Norrina B Allen, Colby Ayers, Jared P Reis, Henrique T Moreira, Stephen Sidney, Jamal S Rana, David R Jacobs, Lisa S Chow, James A de Lemos, Mercedes Carnethon, Jarett D Berry
OBJECTIVES: This study sought to evaluate the association between early-life cardiorespiratory fitness (CRF) and measures of left ventricular (LV) structure and function in midlife. BACKGROUND: Low CRF in midlife is associated with a higher risk of heart failure. However, the unique contributions of early-life CRF toward measures of LV structure and function in middle age are not known. METHODS: CARDIA (Coronary Artery Risk Development in Young Adults) study participants with a baseline maximal treadmill test and an echocardiogram at year 25 were included...
March 5, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28285118/dynamic-changes-in-aortic-vascular-stiffness-in-patients-bridged-to-transplant%C3%A2-with-continuous-flow-left%C3%A2-ventricular-assist-devices
#8
Amit C Patel, R Blair Dodson, William K Cornwell, Kendall S Hunter, Joseph C Cleveland, Andreas Brieke, JoAnn Lindenfeld, Amrut V Ambardekar
OBJECTIVES: The aim of this study was to measure aortic vascular stiffness from orthotopic heart transplant (OHT) patients exposed to varying types of flow as a result of the presence or absence of left ventricular assist device (LVAD) support pre-OHT. BACKGROUND: The effects of continuous-flow LVADs (CF-LVADs) on vascular properties are unknown, but may contribute to the pathophysiology of CF-LVAD complications such as stroke, hypertension, and bleeding. METHODS: Echocardiograms were reviewed from 172 OHT patients immediately before LVAD and at 3 time points post-OHT: baseline, 6 months, and 1 year...
March 4, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28285117/acute-heart-failure-alternatives-to-hospitalization
#9
REVIEW
Reka Zsilinszka, Robert J Mentz, Adam D DeVore, Zubin J Eapen, Peter S Pang, Adrian F Hernandez
Acute heart failure (HF) is a major public health problem with substantial associated economic costs. Because most patients who present to hospitals are admitted irrespective of their level of risk, novel approaches to manage acute HF are needed, such as the use of same-day access clinics for outpatient diuresis and observation units from the emergency department. Current published data lacks a comprehensive overview of the present state of acute HF management in various clinical settings. This review summarizes the strengths and limitations of acute HF care in the outpatient and emergency department settings...
March 4, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28189578/meta-analysis-of-soluble-suppression-of%C3%A2-tumorigenicity-2-and-prognosis-in-acute-heart-failure
#10
Alberto Aimo, Giuseppe Vergaro, Andrea Ripoli, Antoni Bayes-Genis, Domingo A Pascual Figal, Rudolf A de Boer, Johan Lassus, Alexandre Mebazaa, Etienne Gayat, Tobias Breidthardt, Zaid Sabti, Christian Mueller, Hans-Peter Brunner-La Rocca, W H Wilson Tang, Justin L Grodin, Yuhui Zhang, Paulo Bettencourt, Alan S Maisel, Claudio Passino, James L Januzzi, Michele Emdin
OBJECTIVES: The aim of this study was to perform a meta-analysis of currently available data regarding the prognostic significance of soluble suppression of tumorigenecity-2 (sST2) concentration in acute heart failure (AHF). BACKGROUND: Concentration of sST2 may have prognostic value in AHF. A comprehensive assessment of all available studies regarding sST2 in AHF is lacking. METHODS: Three databases (MEDLINE, Cochrane Library, and Scopus) were searched...
February 8, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28285121/a-novel-rehabilitation-intervention-for%C3%A2-older-patients-with-acute%C3%A2-decompensated%C3%A2-heart-failure-the-rehab-hf-pilot-study
#11
Gordon R Reeves, David J Whellan, Christopher M O'Connor, Pamela Duncan, Joel D Eggebeen, Timothy M Morgan, Leigh Ann Hewston, Amy Pastva, Mahesh J Patel, Dalane W Kitzman
OBJECTIVES: This study sought to assess a novel physical rehabilitation intervention in older patients hospitalized for acute decompensated heart failure (ADHF). BACKGROUND: After ADHF, older patients, who are frequently frail with multiple comorbidities, have prolonged and incomplete recovery of physical function and remain at high risk for poor outcomes. METHODS: The REHAB-HF (Rehabilitation Therapy in Older Acute Heart Failure Patients) pilot study was a 3-site, randomized, attention-controlled pilot study of a tailored, progressive, multidomain physical rehabilitation intervention beginning in the hospital and continuing for 12 weeks post-discharge in patients ≥60 years hospitalized with ADHF...
May 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28359423/correction
#12
(no author information available yet)
No abstract text is available yet for this article.
April 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28359422/data-sharing-from-the-editors-perspective-our-hope-with-limitations
#13
EDITORIAL
Christopher M O'Connor, Dirk J van Veldhuisen
No abstract text is available yet for this article.
April 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28359421/amiodarone-and-beta-blockers-in-patients-with-heart-failure-and-atrial-fibrillation
#14
LETTER
Julia Cadrin-Tourigny, Azadeh Shohoudi, Denis Roy, Paul Khairy
No abstract text is available yet for this article.
April 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28359420/reply-factors-that-may-affect-body-change-during-and-after-hospitalization-for-acute-heart-failure
#15
LETTER
Lukasz P Cerbin, Andrew P Ambrosy, Robert J Mentz
No abstract text is available yet for this article.
April 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28359419/factors-that-may-affect-body-change-during-and-after-hospitalization-for-acute-heart-failure
#16
LETTER
Somwail Rasla, Amr El Meligy, Roy Souaid, Aaron Wheeler
No abstract text is available yet for this article.
April 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28359418/partnering-with-patients-to-develop-better-heart-failure-trials
#17
LETTER
Cynthia Chauhan
No abstract text is available yet for this article.
April 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28359417/early-adoption-of-sacubitril-valsartan-for-patients-with-heart-failure-with-reduced-ejection-fraction-insights-from-get-with-the-guidelines-heart-failure-gwtg-hf
#18
Nancy Luo, Gregg C Fonarow, Steven J Lippmann, Xiaojuan Mi, Paul A Heidenreich, Clyde W Yancy, Melissa A Greiner, Bradley G Hammill, N Chantelle Hardy, Stuart J Turner, Warren K Laskey, Lesley H Curtis, Adrian F Hernandez, Robert J Mentz, Emily C O'Brien
OBJECTIVES: The aim of this study was to assess the prevalence and variation in angiotensin receptor/neprilysin inhibitor (ARNI) prescription among a real-world population with heart failure with reduced ejection fraction (HFrEF). BACKGROUND: The U.S. Food and Drug Administration approved sacubitril/valsartan for patients with HFrEF in July 2015. Little is known about the early patterns of use of this novel therapy. METHODS: The study included patients discharged alive from hospitals in Get With the Guidelines-Heart Failure (GWTG-HF), a registry of hospitalized patients with heart failure, between July 2015 and June 2016 who had documentation of whether ARNIs were prescribed at discharge...
April 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28359416/prognostic-outcomes-in-patients-with-heart-failure-a-new-supar-biomarker-for-risk-prediction
#19
EDITORIAL
Christopher Pemberton
No abstract text is available yet for this article.
April 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28359415/soluble-urokinase-type-plasminogen-activator-receptor-improves-risk%C3%A2-prediction-in-patients-with-chronic%C3%A2-heart%C3%A2-failure
#20
Lorenz Koller, Stefan Stojkovic, Bernhard Richter, Patrick Sulzgruber, Christos Potolidis, Florian Liebhart, Deddo Mörtl, Rudolf Berger, Georg Goliasch, Johann Wojta, Martin Hülsmann, Alexander Niessner
OBJECTIVES: This study investigated the predictive value of soluble urokinase-type plasminogen activator receptor (suPAR) in patients with chronic heart failure (CHF). BACKGROUND: SuPAR originates from proteolytic cleavage of the membrane-bound receptor from activated immune and endothelial cells and reflects the level of immune activation. As inflammation plays a crucial role in the complex pathophysiology of CHF, we hypothesized that suPAR might be a suitable prognostic biomarker in patients with CHF...
April 2017: JACC. Heart Failure
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