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JACC. Heart Failure

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https://www.readbyqxmd.com/read/30007559/hvad-the-endurance-supplemental-trial
#1
Carmelo A Milano, Joseph G Rogers, Antone J Tatooles, Geetha Bhat, Mark S Slaughter, Emma J Birks, Nahush A Mokadam, Claudius Mahr, Jeffrey S Miller, David W Markham, Valluvan Jeevanandam, Nir Uriel, Keith D Aaronson, Thomas A Vassiliades, Francis D Pagani
OBJECTIVES: The aim of this study was to prospectively evaluate the impact of blood pressure management on stroke rates in patients receiving the HeartWare HVAD System. BACKGROUND: The ENDURANCE trial demonstrated noninferiority of the HeartWare HVAD System versus control (HeartMate II) in patients with advanced heart failure ineligible for heart transplantation. However, stroke was more common in HVAD subjects. Post hoc analyses demonstrated increased mean arterial blood pressure as a significant independent risk factor for stroke...
July 6, 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30007556/ambulatory-inotrope-infusions-in-advanced-heart-failure-a-systematic-review-and-meta-analysis
#2
Tiana Nizamic, M Hassan Murad, Larry A Allen, Colleen K McIlvennan, Sara E Wordingham, Daniel D Matlock, Shannon M Dunlay
OBJECTIVES: This study sought to systematically review the available evidence of risks and benefits of ambulatory intravenous inotrope therapy in advanced heart failure (HF). BACKGROUND: Ambulatory inotrope infusions are sometimes offered to patients with advanced Stage D HF; however, an understanding of the relative risks and benefits is lacking. METHODS: On August 7, 2016, we searched SCOPUS, Web of Science, Ovid EMBASE, and Ovid MEDLINE for studies of long-term use of intravenous inotropes in outpatients with advanced HF...
July 6, 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30007555/ambulatory-inotrope-infusions-the-importance-of-historical-perspective
#3
EDITORIAL
Carl V Leier
No abstract text is available yet for this article.
July 6, 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/29885951/trying-to-make-progress-on-survival-in-a-complicated-area-sudden-death-in-hfpef
#4
EDITORIAL
Peter E Carson
No abstract text is available yet for this article.
May 31, 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/29803553/left-atrial-pressure-the-key-to-understand-and-treat-hfpef
#5
EDITORIAL
Gerd Hasenfuss
No abstract text is available yet for this article.
May 21, 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/29803552/hemodynamic-correlates-and-diagnostic-role-of-cardiopulmonary-exercise-testing-in-heart-failure-with-preserved-ejection-fraction
#6
Yogesh N V Reddy, Thomas P Olson, Masaru Obokata, Vojtech Melenovsky, Barry A Borlaug
OBJECTIVES: The authors sought to define the invasive hemodynamic correlates of peak oxygen consumption (Vo2 ) in both supine and upright exercise in heart failure with preserved ejection fraction (HFpEF) and evaluate its diagnostic role as a method to discriminate HFpEF from noncardiac etiologies of dyspnea (NCD). BACKGROUND: Peak Vo2 is depressed in patients with HFpEF. The hemodynamic correlates of reduced peak Vo2 and its role in the clinical evaluation of HFpEF are unclear...
May 21, 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30078394/fat-female-fatigued-features-of-the-obese-hfpef-phenotype
#7
EDITORIAL
Carolyn S P Lam, Chanchal Chandramouli
No abstract text is available yet for this article.
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30078393/mineralocorticoid-receptor-antagonism-for-the-treatment-of-af-and-hfpef-preserving-hope
#8
EDITORIAL
Adam D DeVore, Jonathan P Piccini
No abstract text is available yet for this article.
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30071957/reply-time-to-diuretic-in-acute-heart-failure
#9
LETTER
Jin Joo Park, Dong-Ju Choi
No abstract text is available yet for this article.
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30071956/chronic-heart-failure-care-and-costs-what-is-the-efficiency-of-investing-in-quality
#10
LETTER
Miguel Cainzos-Achirica, Marta Trapero-Bertran, Usama Bilal, Xavier Corbella, Josep Comin-Colet
No abstract text is available yet for this article.
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30071955/time-to-diuretic-in-acute-heart-failure
#11
LETTER
Desiree Wussler, Joan Walter, Jeanne du Fay de Lavallaz, Ivo Strebel, Christian Mueller
No abstract text is available yet for this article.
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30071954/reply-catecholamine-mediated-pathways-in-takotsubo-syndrome-does-it-matter-if-it-is-a-serotonin-norepinephrine-reuptake-inhibitor-or-a-selective-serotonin-reuptake-inhibitor
#12
LETTER
Daniel Woronow, Courtney Suggs, Robert Levin, Ida-Lina Diak, Cindy Kortepeter
No abstract text is available yet for this article.
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30071953/catecholamine-mediated-pathways-in-takotsubo-syndrome-does-it-matter-if-it-is-a-serotonin-norepinephrine-reuptake-inhibitor-or-a-selective-serotonin-reuptake-inhibitor
#13
LETTER
Andre Dias, Emiliana Franco, Vincent M Figueredo
No abstract text is available yet for this article.
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30071952/hfpef-from-early-observations-to-worldwide-awareness
#14
EDITORIAL
Christopher M O'Connor
No abstract text is available yet for this article.
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30071951/weighty-matters-in-hfpef-and-aging
#15
EDITORIAL
Daniel E Forman, Bret H Goodpaster
No abstract text is available yet for this article.
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30071950/heart-failure-with-preserved-ejection-fraction-expert-panel-report-current-controversies-and-implications-for-clinical-trials
#16
REVIEW
Kishan S Parikh, Kavita Sharma, Mona Fiuzat, Howard K Surks, Jyothis T George, Narimon Honarpour, Christopher Depre, Patrice Desvigne-Nickens, Richard Nkulikiyinka, Gregory D Lewis, Mardi Gomberg-Maitland, Christopher M O'Connor, Norman Stockbridge, Robert M Califf, Marvin A Konstam, James L Januzzi, Scott D Solomon, Barry A Borlaug, Sanjiv J Shah, Margaret M Redfield, G Michael Felker
The number of persons with heart failure has continued to rise over the last several years. Approximately one-half of those living with heart failure have heart failure with preserved ejection fraction, but critical unsolved questions remain across the spectrum of basic, translational, clinical, and population research in heart failure with preserved ejection fraction. In this study, the authors summarize existing knowledge, persistent controversies, and gaps in evidence with regard to the understanding of heart failure with preserved ejection fraction...
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30007560/temporal-trends-in-the-incidence-of-and-mortality-associated-with-heart-failure-with-preserved-and-reduced-ejection-fraction
#17
Connie W Tsao, Asya Lyass, Danielle Enserro, Martin G Larson, Jennifer E Ho, Jorge R Kizer, John S Gottdiener, Bruce M Psaty, Ramachandran S Vasan
OBJECTIVES: This study aimed to determine temporal trends in the incidence of and mortality associated with heart failure (HF) and its subtypes (heart failure with reduced ejection fraction [HFrEF] and heart rate with preserved ejection fraction [HFpEF]) in the community. BACKGROUND: Major shifts in cardiovascular disease risk factor prevalence and advances in therapies may have influenced HF incidence and mortality. METHODS: In the FHS (Framingham Heart Study) and CHS (Cardiovascular Health Study), for participants who were ≥60 years of age and free of HF (n = 15,217; 60% women; 2,524 incident HF cases; 115,703 person-years of follow-up), we estimated adjusted incidence rate ratios of HF, HFrEF, and HFpEF from 1990 to 1999 and 2000 to 2009...
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30007558/regional-adipose-distribution-and-its-relationship-to-exercise-intolerance-in-older-obese-patients-who-have-heart-failure-with-preserved-ejection-fraction
#18
Mark J Haykowsky, Barbara J Nicklas, Peter H Brubaker, W Gregory Hundley, Tina E Brinkley, Bharathi Upadhya, J Thomas Becton, Michael D Nelson, Haiying Chen, Dalane W Kitzman
OBJECTIVES: This study sought to test the hypothesis that older obese patients with heart failure with preserved ejection fraction (HFpEF) have significantly greater abdominal, cardiac, and intermuscular fat than healthy, age-matched controls, out of proportion to total body fat, and that these abnormalities are associated with objective measurements of physical function. BACKGROUND: Recent studies indicate that excess total body adipose tissue contributes to exercise intolerance in patients with HFpEF...
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30007557/atrial-fibrillation-in-heart-failure-with-preserved-ejection-fraction-the-topcat-trial
#19
Maja Cikes, Brian Claggett, Amil M Shah, Akshay S Desai, Eldrin F Lewis, Sanjiv J Shah, Inder S Anand, Eileen O'Meara, Jean L Rouleau, Nancy K Sweitzer, James C Fang, Sanjeev Saksena, Bertram Pitt, Marc A Pfeffer, Scott D Solomon
OBJECTIVES: This study assessed the relationship between atrial fibrillation (AF) and outcomes in the TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) trial, to evaluate whether AF modified the treatment response to spironolactone and whether spironolactone influenced post-randomization AF. BACKGROUND: AF is common in heart failure with preserved ejection fraction (HFpEF) and likely contributes to increased risk of adverse outcomes...
August 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/30007554/the-association-of-obesity-and-cardiometabolic-traits-with-incident-hfpef-and-hfref
#20
Nazir Savji, Wouter C Meijers, Traci M Bartz, Vijeta Bhambhani, Mary Cushman, Matthew Nayor, Jorge R Kizer, Amy Sarma, Michael J Blaha, Ron T Gansevoort, Julius M Gardin, Hans L Hillege, Fei Ji, Willem J Kop, Emily S Lau, Douglas S Lee, Ruslan Sadreyev, Wiek H van Gilst, Thomas J Wang, Markella V Zanni, Ramachandran S Vasan, Norrina B Allen, Bruce M Psaty, Pim van der Harst, Daniel Levy, Martin Larson, Sanjiv J Shah, Rudolf A de Boer, John S Gottdiener, Jennifer E Ho
OBJECTIVES: This study evaluated the associations of obesity and cardiometabolic traits with incident heart failure with preserved versus reduced ejection fraction (HFpEF vs. HFrEF). Given known sex differences in HF subtype, we examined men and women separately. BACKGROUND: Recent studies suggest that obesity confers greater risk of HFpEF versus HFrEF. Contributions of associated metabolic traits to HFpEF are less clear. METHODS: We studied 22,681 participants from 4 community-based cohorts followed for incident HFpEF versus HFrEF (ejection fraction ≥50% vs...
August 2018: JACC. Heart Failure
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