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JACC. Heart Failure

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https://www.readbyqxmd.com/read/28089314/heart-failure-complicated-by-atrial%C3%A2-fibrillation-don-t-bury-the-beta-blockers-just-yet
#1
EDITORIAL
Jonathan P Piccini, Larry A Allen
No abstract text is available yet for this article.
January 6, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28089316/decreased-mortality-with-beta-blockers-in%C3%A2-patients-with-heart-failure-and-coexisting-atrial-fibrillation-an-af-chf-substudy
#2
Julia Cadrin-Tourigny, Azadeh Shohoudi, Denis Roy, Mario Talajic, Rafik Tadros, Blandine Mondésert, Katia Dyrda, Léna Rivard, Jason G Andrade, Laurent Macle, Peter G Guerra, Bernard Thibault, Marc Dubuc, Paul Khairy
OBJECTIVES: The impact of beta-blockers on mortality and hospitalizations was assessed in the largest randomized trial of patients with both atrial fibrillation (AF) and heart failure with a reduced ejection fraction (HFrEF): the Atrial Fibrillation-Congestive Heart Failure trial. BACKGROUND: Although beta-blockers are the cornerstone of therapy for HFrEF, a recent patient-level meta-analysis cast doubt on their efficacy in patients with coexisting AF. METHODS: From a total of 1,376 subjects randomized in the AF-CHF trial, those without beta-blockers at baseline were propensity matched to a maximum of 2 exposed patients...
January 4, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28089315/racial-tension-in-hypertension-divergent-effects-of-african-and-european-ancestry-on-cardiac-remodeling
#3
EDITORIAL
Walter J Paulus, Mark T Waddingham
No abstract text is available yet for this article.
January 4, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28089313/optimism-pessimism-and-pragmatism-musings-on-the-cost-of-medical-innovation
#4
EDITORIAL
Joseph G Rogers
No abstract text is available yet for this article.
January 4, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017356/race-related-differences-in-left%C3%A2-ventricular-structural-and-functional%C3%A2-remodeling-in-response%C3%A2-to%C3%A2-increased-afterload-the-aric-study
#5
Miguel M Fernandes-Silva, Amil M Shah, Sheila Hegde, Alexandra Goncalves, Brian Claggett, Susan Cheng, Wilson Nadruz, Dalane W Kitzman, Suma H Konety, Kunihiro Matsushita, Thomas Mosley, Carolyn S P Lam, Barry A Borlaug, Scott D Solomon
OBJECTIVES: The aim of this study was to evaluate racial differences in arterial elastance (Ea), which reflects the arterial afterload faced by the left ventricle, and its associations with cardiac structure and function. The hypothesis under study was that the left ventricle in blacks displays heightened afterload sensitivity compared with whites. BACKGROUND: Chronic increasing in arterial afterload may be an important trigger for left ventricular (LV) remodeling and dysfunction that lead to heart failure...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017355/atrial-fibrillation-in-heart-failure-with-preserved-ejection-fraction-association-with-exercise-capacity-left-ventricular-filling-pressures-natriuretic-peptides-and-left-atrial-volume
#6
Carolyn S P Lam, Michiel Rienstra, Wan Ting Tay, Licette C Y Liu, Yoran M Hummel, Peter van der Meer, Rudolf A de Boer, Isabelle C Van Gelder, Dirk J van Veldhuisen, Adriaan A Voors, Elke S Hoendermis
OBJECTIVES: This study sought to study the association of atrial fibrillation (AF) with exercise capacity, left ventricular filling pressure, natriuretic peptides, and left atrial size in heart failure with preserved ejection fraction (HFpEF). BACKGROUND: The diagnosis of heart failure with preserved ejection fraction (HFpEF) in patients with AF remains a challenge because both contribute to impaired exercise capacity, and increased natriuretic peptides and left atrial volume...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017354/does-size-matter-with-continuous-left%C3%A2-ventricular-assist-devices
#7
EDITORIAL
Eileen M Hsich
No abstract text is available yet for this article.
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017353/significance-of-residual-mitral-regurgitation-after-continuous-flow-left%C3%A2-ventricular-assist-device-implantation
#8
Hayah Kassis, Krishna Cherukuri, Richa Agarwal, Manreet Kanwar, Subbarao Elapavaluru, George G Sokos, Robert J Moraca, Stephen H Bailey, Srinivas Murali, Raymond L Benza, Amresh Raina
OBJECTIVES: This study hypothesized that the presence of residual mitral regurgitation (MR) post-continuous flow (CF) left ventricular assist device (LVAD) implantation based on quantitative assessment would be negatively associated with right ventricular (RV) size and function and clinical outcomes. BACKGROUND: MR is associated with elevated left atrial pressure, secondary pulmonary hypertension and RV dysfunction. Implantation of a LVAD leads to mechanical unloading of the left ventricle and generally improves MR...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017352/the-influence-of-age-on-hemodynamic-parameters-during-rest-and-exercise-in%C3%A2-healthy-individuals
#9
Emil Wolsk, Rine Bakkestrøm, Jacob H Thomsen, Louise Balling, Mads J Andersen, Jordi S Dahl, Christian Hassager, Jakob E Møller, Finn Gustafsson
OBJECTIVES: The authors sought to obtain hemodynamic estimates across a wide age span and in both sexes for future reference and compare these estimates with current guideline diagnostic hemodynamic thresholds for abnormal filling pressure and pulmonary hypertension. BACKGROUND: At present, the influence of age on hemodynamic function is largely unknown. Because many diseases with proposed cardiac impact are more prevalent in the older population, it is pivotal to know how hemodynamic parameters are affected by age itself to discern the influence of disease from that of physiological aging...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017351/cost-effectiveness-of-left-ventricular-assist-devices-in-ambulatory-patients-with-advanced-heart-failure
#10
Jacqueline Baras Shreibati, Jeremy D Goldhaber-Fiebert, Dipanjan Banerjee, Douglas K Owens, Mark A Hlatky
OBJECTIVES: This study assessed the cost-effectiveness of left ventricular assist devices (LVADs) as destination therapy in ambulatory patients with advanced heart failure. BACKGROUND: LVADs improve survival and quality of life in inotrope-dependent heart failure, but data are limited as to their value in less severely ill patients. METHODS: We determined costs of care among Medicare beneficiaries before and after LVAD implantation from 2009 to 2010...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017350/myocardial-injury-obesity-and-the-obesity-paradox-the-aric-study
#11
Yashashwi Pokharel, Wensheng Sun, Salim S Virani, Vijay Nambi, Ron C Hoogeveen, Patricia P Chang, Chiadi E Ndumele, Scott D Solomon, Biykem Bozkurt, Elizabeth Selvin, Christie M Ballantyne, Anita Deswal
OBJECTIVES: This study sought to determine whether pre-heart failure (HF) myocardial injury explains the differential mortality after HF across weight categories. BACKGROUND: Obesity is a risk factor for HF, but pre-HF obesity is associated with lower mortality after incident HF. High-sensitivity cardiac troponin T (hs-cTnT) is a sensitive marker of myocardial injury, and predicts incident HF and mortality. METHODS: Stratifying 1,279 individuals with incident HF hospitalizations by their pre-HF hs-cTnT levels (< and ≥ 14 ng/l), we examined the association of pre-HF body mass index (BMI) with mortality after incident HF hospitalization in the ARIC (Atherosclerosis Risk In Communities) study...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017349/predictors-and-prognostic-implications-of-incident-heart-failure-in-patients-with-prevalent-atrial-fibrillation
#12
Ambarish Pandey, Sunghee Kim, Curtiss Moore, Laine Thomas, Bernard Gersh, Larry A Allen, Peter R Kowey, Kenneth W Mahaffey, Elaine Hylek, Eric D Peterson, Jonathan P Piccini, Gregg C Fonarow
OBJECTIVES: The purpose of this study was to determine the significant clinical predictors of incident heart failure (HF) and its prognostic effect on long-term outcomes among community-based patients with established atrial fibrillation (AF). BACKGROUND: AF is associated with an increased risk of HF. However, in this population, little focus is placed on risk stratification for and the prevention of HF. METHODS: Patients with AF but without HF at baseline enrolled in the ORBIT-AF (Outcomes Registry for Informed Treatment of Atrial Fibrillation) registry were included...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017348/late-gadolinium-enhancement-and-the%C3%A2-risk-for-ventricular-arrhythmias-or-sudden%C3%A2-death-in-dilated-cardiomyopathy-systematic-review-and-meta-analysis
#13
Andrea Di Marco, Ignasi Anguera, Matthias Schmitt, Igor Klem, Thomas Neilan, James A White, Marek Sramko, Pier Giorgio Masci, Andrea Barison, Peter Mckenna, Ify Mordi, Kristina H Haugaa, Francisco Leyva, Jorge Rodriguez Capitán, Hiroshi Satoh, Takeru Nabeta, Paolo Domenico Dallaglio, Niall G Campbell, Xavier Sabaté, Ángel Cequier
OBJECTIVES: The aim of this study was to evaluate the association between late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging and ventricular arrhythmias or sudden cardiac death (SCD) in patients with dilated cardiomyopathy (DCM). BACKGROUND: Risk stratification for SCD in DCM needs to be improved. METHODS: A systematic review and meta-analysis were conducted. A systematic search of PubMed and Ovid was performed, and observational studies that analyzed the arrhythmic endpoint (sustained ventricular arrhythmia, appropriate implantable cardioverter-defibrillator [ICD] therapy, or SCD) in patients with DCM, stratified by the presence or absence of LGE, were included...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017347/prevalence-and-clinical-significance-of%C3%A2-diabetes-in-asian-versus-white-patients%C3%A2-with-heart-failure
#14
Ingrid E M Bank, Crystel M Gijsberts, Tiew-Hwa K Teng, Lina Benson, David Sim, Poh Shuan Daniel Yeo, Hean Yee Ong, Fazlur Jaufeerally, Gerard K T Leong, Lieng H Ling, A Mark Richards, Dominique P V de Kleijn, Ulf Dahlström, Lars H Lund, Carolyn S P Lam
OBJECTIVES: The study sought to compare the prevalence, clinical correlates and prognostic impact of diabetes in Southeast Asian versus white patients with heart failure (HF) with preserved or reduced ejection fraction. BACKGROUND: Diabetes mellitus is common in HF and is associated with impaired prognosis. Asia is home to the majority of the world's diabetic population, yet data on the prevalence and clinical significance of diabetes in Asian patients with HF are sparse, and no studies have directly compared Asian and white patients...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28017346/body-weight-change-during-and-after%C3%A2-hospitalization-for-acute-heart%C3%A2-failure-%C3%A2-patient-characteristics-markers-of-congestion-and-outcomes-findings-from-ascend-hf
#15
Andrew P Ambrosy, Lukasz P Cerbin, Paul W Armstrong, Javed Butler, Adrian Coles, Adam D DeVore, Mark E Dunlap, Justin A Ezekowitz, G Michael Felker, Marat Fudim, Stephen J Greene, Adrian F Hernandez, Christopher M O'Connor, Philip Schulte, Randall C Starling, John R Teerlink, Adriaan A Voors, Robert J Mentz
OBJECTIVES: This study sought to examine the relationships between in-hospital and post-discharge body weight changes and outcomes among patients hospitalized for acute heart failure (AHF). BACKGROUND: Body weight changes during and after hospitalization for AHF and the relationships with outcomes have not been well characterized. METHODS: A post hoc analysis was performed of the ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure) trial, which enrolled patients admitted for AHF regardless of ejection fraction...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/27816512/prognostic-value-of-soluble-suppression-of-tumorigenicity-2-in-chronic-heart-failure-a-meta-analysis
#16
Alberto Aimo, Giuseppe Vergaro, Claudio Passino, Andrea Ripoli, Bonnie Ky, Wayne L Miller, Antoni Bayes-Genis, Inder Anand, James L Januzzi, Michele Emdin
OBJECTIVES: The purpose of this study was to perform the first meta-analysis of currently available data. BACKGROUND: Soluble suppression of tumorigenesis 2 (sST2) plasma concentration is elevated in chronic heart failure (CHF) and helps to predict prognosis in this setting, although the evidence is limited. METHODS: Three databases (Medline, Cochrane Library, and Scopus) were searched. Inclusion criteria were: follow-up studies; papers published in English; enrollment of CHF outpatients; available data on hazard ratio (HR) for the log2 ST2 (so that the reported HRs represent the risk per doubling of sST2) and 95% confidence interval (CI) for all-cause death, and possibly also for cardiovascular (CV) death; and use of standardized sST2 assay...
October 27, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/27816511/does-small-size-matter-with-continuous%C3%A2-flow-devices-analysis-of-the-intermacs-database-of-adults-with-bsa%C3%A2-%C3%A2-1-5-m-2
#17
Farhan Zafar, Chet R Villa, David L Morales, Elizabeth D Blume, David N Rosenthal, James K Kirklin, Angela Lorts
OBJECTIVES: This study investigated how small patient size affects clinical outcomes in patients implanted with a continuous flow left ventricular assist device (CFLVAD). BACKGROUND: The development of smaller CFLVADs has allowed ventricular assist device (VAD) use in anatomically smaller patients; however, limited outcome data exist regarding CFLVAD use in patients with a body surface area (BSA) ≤1.5 m(2). METHODS: All CFLVAD patients entered in the Interagency Registry for Mechanically Assisted Circulatory Support registry April 2008 to September 2013 and with BSA data were included...
October 27, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/28034383/correction
#18
(no author information available yet)
No abstract text is available yet for this article.
January 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28034382/reply-is-counting-one-s-chickens-before-they-are-hatched-an-inevitable-ending
#19
LETTER
Chance M Witt, Yong-Mei Cha
No abstract text is available yet for this article.
January 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28034381/is-counting-one-s-chickens-before-they%C3%A2-are-hatched-an-inevitable-ending
#20
LETTER
Levent Cerit, Hamza Duygu
No abstract text is available yet for this article.
January 2017: JACC. Heart Failure
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