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Journal of Allergy and Clinical Immunology in Practice

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https://www.readbyqxmd.com/read/29226808/increased-tolerance-to-less-extensively-heat-denatured-baked-milk-products-in-milk-allergic-children
#1
Anna Nowak-Węgrzyn, Kaitie Lawson, Madhan Masilamani, Jacob Kattan, H T Bahnson, Hugh A Sampson
BACKGROUND: Most milk-allergic children tolerate baked milk. OBJECTIVE: To investigate the effect of more frequent versus less frequent introduction of higher doses of more allergenic (less heat-denatured) forms of milk (MAFM) on progression to tolerance. METHODS: Milk-allergic children were challenged with increasing doses of MAFM; baked foods were incorporated into the diet; challenges were repeated at 6- or 12-month intervals over 36 months...
December 6, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29226807/asthma-family-history-of-drug-allergy-and-age-predict-amoxicillin-allergy-in-children
#2
Yoram Faitelson, Mona Boaz, Ilan Dalal
BACKGROUND: Suspected adverse reactions to amoxicillin are common, but there are no known factors that can predict amoxicillin allergy in children. In addition, methods used for the diagnosis of amoxicillin allergy are not standardized and their role in diagnosis is not clear. OBJECTIVE: To identify predictive factors and to assess the role of skin test in the diagnosis of amoxicillin allergy in children. METHODS: Children with a history of immediate (excluding anaphylaxis) or nonimmediate reactions to amoxicillin were tested by skin prick test, followed by oral graded challenge with amoxicillin...
December 6, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29226806/underestimation-of-specific-ige-measurements-using-extract-based-assays-on-undiluted-sera-revealed-through-dilution
#3
Alexander J Schuyler, Anubha Tripathi, Lisa J Workman, Jeffrey M Wilson, Elizabeth A Erwin, Monica G Lawrence, Emily C McGowan, Robert G Hamilton, Thomas A E Platts-Mills
No abstract text is available yet for this article.
December 6, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29226805/anaphylaxis-to-invasive-chlorhexidine-administration-despite-tolerance-of-topical-chlorhexidine-use
#4
Anna Postolova, Jonathan T Bradley, David Parris, Janell Sherr, Sean A McGhee, Joseph D Hernandez
No abstract text is available yet for this article.
December 6, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29221919/impact-of-lifestyle-interventions-targeting-healthy-diet-physical-activity-and-weight-loss-on-asthma-in-adults-what-is-the-evidence
#5
Sharmilee M Nyenhuis, Anne E Dixon, Jun Ma
Unhealthy lifestyle factors such as poor diet quality, sedentary lifestyle, and obesity are associated with negative health consequences in asthma including poor asthma control, impaired quality of life, and greater health care utilization. Lifestyle modification is the cornerstone of behavioral treatments and has been effective in chronic diseases such as atherothrombotic vascular disease and diabetes. There is a critical need for lifestyle interventions in asthma care that address obesity and its intimately linked risk behaviors in terms of poor diet and physical inactivity...
December 5, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29221918/low-variability-in-peak-expiratory-flow-predicts-successful-inhaled-corticosteroid-step-down-in-adults-with-asthma
#6
Naomi Tsurikisawa, Chiyako Oshikata, Toshio Sato, Goro Kimura, Masami Mizuki, Takahiro Tsuburai, Shunsuke Shoji, Hiroshi Saito, Terufumi Shimoda
BACKGROUND: The prognosis for patients beyond 1 year after reduction of their inhaled corticosteroid (ICS) dose remains unknown. Predictive factors that can be evaluated before the initiation of asthma treatment or at ICS dose reduction are unknown. METHODS: We prospectively studied 223 patients in 6 hospitals in the National Hospital Organization of Japan during the 36 months after 50% reduction of their daily ICS dose. All patients recorded their morning and evening peak expiratory flows (PEFs) in their diaries...
December 5, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29198698/successful-intravenous-immunoglobulin-treatment-in-pediatric-severe-dress-syndrome
#7
Nufar Marcus, Keren Smuel, Moran Almog, Dario Prais, Rachel Straussberg, Daniel Landau, Oded Scheuerman
BACKGROUND: Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare, potentially life-threatening delayed drug-induced hypersensitivity reaction. The most frequently reported drugs causing DRESS are aromatic antiepileptic agents. Prompt withdrawal of the offending drug and administering systemic corticosteroids is the most widely accepted and used treatment. The treatment of severe DRESS not responsive to systemic corticosteroids is uncertain. OBJECTIVE: The objective of this study was to describe a case series of pediatric patients with DRESS who were treated successfully with intravenous immunoglobulins (IVIGs)...
November 30, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29196087/a-patient-with-anaphylaxis-to-diphenhydramine-without-cross-reactivity-to-loratadine
#8
Elaine Y L Au, Jaime S Rosa Duque, Chak Sing Lau, Eric Chan
No abstract text is available yet for this article.
November 29, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29196086/use-of-the-internet-by-patients-attending-allergy-clinics-and-its-potential-as-a-tool-that-better-meets-patients-needs
#9
Laura V Carpio-Escalona, David González-de-Olano
No abstract text is available yet for this article.
November 29, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29196085/technology-interventions-for-nonadherence-new-approaches-to-an-old-problem
#10
Bruce G Bender
Nonadherence to asthma medications is well recognized. Interventions to improve adherence, however, have been only moderately successful and are not often adopted because of limited provider time, training, or institutional support. The potential for mobile communication technology to improve adherence has gathered sharply growing interest. Technology-based adherence tracking devices have been in existence for almost 3 decades, but have only recently reached a level of reliability and utility to be considered in allergy practice...
November 29, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29175371/natural-history-of-benign-nonimmediate-allergy-to-beta-lactams-in-children-a-prospective-study-in-retreated-patients-after-a-positive-and-a-negative-provocation-test
#11
Aude Tonson la Tour, Marine Michelet, Philippe A Eigenmann, Jean-Christoph Caubet
BACKGROUND: The drug provocation test (DPT) is considered as the gold standard to diagnose drug allergy and is particularly important in the diagnosis of nonimmediate beta-lactam (BL) allergy in children. The natural history of BL allergy remains unknown. OBJECTIVE: Our main aim was to evaluate the natural history of nonimmediate BL hypersensitivity and the long-term tolerance acquisition, and our secondary objective was to determine the negative predictive value (NPV) of the DPT following a 2-day protocol...
November 23, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29175370/atopy-is-associated-with-age-at-asthma-onset-in-elderly-patients
#12
Rosana Câmara Agondi, Mayra Coutinho Andrade, Priscila Takejima, Marcelo Vivolo Aun, Jorge Kalil, Pedro Giavina-Bianchi
BACKGROUND: Asthma in the elderly population (60 years of age and older) is frequently underdiagnosed, as well as atopy. Atopy, although more prevalent in younger patients, can be a major cause of asthma in the elderly. Chronic obstructive pulmonary disease (COPD) and cardiovascular disease are common differential diagnoses, especially in elderly smokers. OBJECTIVE: The objective of this study was to assess atopy and comorbidities in elderly patients with asthma...
November 23, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29175369/serum-ige-as-an-immunological-marker-to-predict-response-to-omalizumab-treatment-in-symptomatic-chronic-urticaria
#13
Matthew D Straesser, Eric Oliver, Thamiris Palacios, Timothy Kyin, James Patrie, Larry Borish, Sarbjit S Saini, Monica G Lawrence
No abstract text is available yet for this article.
November 23, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29175008/recall-urticaria-in-adalimumab-hypersensitivity
#14
Philip H Li, Timothy J Watts, Mei-Shan Lui, Chak-Sing Lau, Ho-Yin Chung
No abstract text is available yet for this article.
November 22, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29174062/tiotropium-respimat-add-on-is-efficacious-in-symptomatic-asthma-independent-of-t2-phenotype
#15
Thomas B Casale, Eric D Bateman, Mark Vandewalker, J Christian Virchow, Hendrik Schmidt, Michael Engel, Petra Moroni-Zentgraf, Huib A M Kerstjens
BACKGROUND: Adding tiotropium to existing inhaled corticosteroid (ICS) maintenance therapy with or without a long-acting β2-agonist (LABA) has been shown to be beneficial in patients with symptomatic asthma. OBJECTIVE: To assess whether responses to tiotropium Respimat add-on therapy were influenced by patients' T2 status. METHODS: In this exploratory study, data from 4 phase III trials were analyzed: once-daily tiotropium 5 μg or placebo as add-on to ICS + LABA (PrimoTinA-asthma; 2 replicate trials; NCT00772538/NCT00776984; n = 912); once-daily tiotropium 5 μg or 2...
November 22, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29174063/health-care-resource-utilization-and-costs-among-adults-with-atopic-dermatitis-in-the-united-states-a-claims-based-analysis
#16
Aaron M Drucker, Abrar A Qureshi, Caroline Amand, Sara Villeneuve, Abhijit Gadkari, Jingdong Chao, Andreas Kuznik, Gaëlle Bégo-Le-Bagousse, Laurent Eckert
BACKGROUND: Data on health care resource utilization (HCRU) and costs for patients with atopic dermatitis (AD) are lacking. OBJECTIVE: The objective of this study was to determine HCRU and costs associated with AD in US adults. METHODS: This retrospective study identified patients with AD from the Truven Health Marketscan Commercial Claims and Encounters database during 2013 based on ≥2 claims with International Classification of Diseases, Ninth Revision code 691...
November 21, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29162426/current-status-and-unanswered-questions-for-food-allergy-treatments
#17
Rima Rachid, Corinne A Keet
Although there is no FDA approved therapy for food allergy, over the past decades, several routes of immunotherapy have been investigated for food allergy. Thus far, these therapies have shown variable levels of efficacy at desensitizing to foods, with oral immunotherapy (OIT) far more successful than sublingual immunotherapy (SLIT) or epicutaneous immunotherapy (EPIT). However, desensitization tends to be temporary, and safety remains a major concern with OIT. Moreover, although it seems logical that desensitization will result in fewer reactions, it is not clear whether OIT or other immunotherapies are associated with an overall lower or higher risk of reactions over the long term...
November 18, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29153881/relationship-of-blood-eosinophil-count-to-exacerbations-in-chronic-obstructive-pulmonary-disease
#18
Robert S Zeiger, Trung N Tran, Rebecca K Butler, Michael Schatz, Qiaowu Li, Deepak B Khatry, Ubaldo Martin, Aniket A Kawatkar, Wansu Chen
BACKGROUND: Eosinophilic airway inflammation characterizes a chronic obstructive pulmonary disease (COPD) phenotype that requires more study. OBJECTIVE: To investigate the relationship of blood eosinophil count to exacerbations in COPD. METHODS: Using administrative pharmacy and health care utilization data from 2009 to 2012, we retrospectively identified patients 40 years or older with a COPD diagnosis, postbronchodilator FEV1/forced vital capacity ratio of less than 0...
November 15, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29153880/food-allergy-is-an-important-risk-factor-for-childhood-asthma-irrespective-of-whether-it-resolves
#19
Evelien M Vermeulen, Jennifer J Koplin, Shyamali C Dharmage, Lyle C Gurrin, Rachel L Peters, Vicki McWilliam, Anne-Louise Ponsonby, Terence Dwyer, Adrian J Lowe, Mimi L K Tang, Katrina J Allen
BACKGROUND: The risk of developing asthma in those with early food allergy is unknown, particularly when early life food allergy has resolved. OBJECTIVE: To understand whether challenge-proven food allergy in infancy increases the risk of asthma at age 4 years, using data from a population-based cohort. METHODS: A total of 5,276 12-month-old infants were recruited using a population-based sampling frame. Infants underwent skin prick test to egg, peanut, and sesame and those with a detectable skin prick test result had oral food challenges...
November 15, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29150253/anti-ige-or-anti-il5-that-is-the-question
#20
REVIEW
Elliot Israel, Reynold A Panettieri
No abstract text is available yet for this article.
November 14, 2017: Journal of Allergy and Clinical Immunology in Practice
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