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Journal of Allergy and Clinical Immunology in Practice

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https://www.readbyqxmd.com/read/29037819/drug-induced-paradoxical-vocal-fold-motion
#1
Marlene Garcia-Neuer, Donna Marie Lynch, Kathleen Marquis, Jayme Dowdall, Mariana Castells, David Edward Sloane
Vocal cord dysfunction, also known as paradoxical vocal fold motion (PVFM), is a disorder characterized by abnormal vocal cord adduction during inspiration. PVFM is commonly misdiagnosed as asthma because of the similarity of symptoms: cough, wheezing, chest pain, and dyspnea. We present the clinical vignette of a 36-year-old woman with juvenile rheumatoid arthritis and multiple adverse drug reactions who presented with recurrent episodes of unrecognized PVFM during skin testing for drug allergy, omalizumab treatment, and tocilizumab desensitization...
October 13, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29033258/persistent-tryptase-elevation-in-a-patient-with-gaucher-disease
#2
Edith Schussler, Amy Yang, Jonathan J Lyons, Joshua D Milner, Julie Wang
No abstract text is available yet for this article.
October 12, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29033257/chromogranin-a-is-not-a-biomarker-of-mastocytosis
#3
Pahul Hanjra, Chyi-Chia R Lee, Irina Maric, Melody Carter, Ana Olivera, Dean D Metcalfe, Hirsh D Komarow
No abstract text is available yet for this article.
October 12, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29030000/occupational-asthma-from-biological-pest-control-in-greenhouses
#4
Irmeli Lindström, Heidi Karvonen, Katri Suuronen, Hille Suojalehto
No abstract text is available yet for this article.
October 10, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29017833/cross-reactivity-in-%C3%AE-lactam-allergy
#5
Robert J Zagursky, Michael E Pichichero
β-Lactam drugs (penicillins, amoxicillin, and cephalosporins) account for 42.6% of all severe drug-induced anaphylaxis. In this review, we focus on clinically significant immunologic cross-reactivity in patients with confirmed penicillin allergy to cephalosporins, and the structural involvement of the R1 and R2 chemical side chains of the cephalosporins causing IgE-mediated cross-reactivity with penicillin and other cephalosporins. Skin tests predict IgE-mediated reactions and showed cross-reactivity between penicillins and early generation cephalosporins that shared side chains, but confirmatory challenge data are lacking...
October 7, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29017832/impact-of-rhinitis-on-work-productivity-a-systematic-review
#6
Olivier Vandenplas, Denis Vinnikov, Paul D Blanc, Ioana Agache, Claus Bachert, Michael Bewick, Lars-Olaf Cardell, Paul Cullinan, Pascal Demoly, Alexis Descatha, Joao Fonseca, Tari Haahtela, Peter W Hellings, Jacques Jamart, Juha Jantunen, Ömer Kalayci, David Price, Boleslaw Samolinski, Joaquin Sastre, Longxiu Tian, Antonio L Valero, Xinyi Zhang, Jean Bousquet
BACKGROUND: Allergic rhinitis (AR) is increasingly acknowledged as having a substantial socioeconomic impact associated with impaired work productivity, although available information remains fragmented. OBJECTIVE: This systematic review summarizes recently available information to provide a quantitative estimate of the burden of AR on work productivity including lost work time (ie, absenteeism) and reduced performance while working (ie, presenteeism). METHODS: A Medline search retrieved original studies from 2005 to 2015 pertaining to the impact of AR on work productivity...
October 7, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28988786/omalizumab-for-severe-chronic-spontaneous-urticaria-real-life-experiences-of-280-patients
#7
Zahava Vadasz, Yuval Tal, Menachem Rotem, Vered Shichter-Confino, Keren Mahlab-Guri, Yael Graif, Aharon Kessel, Nancy Agmon-Levin, Ramit Maoz-Segal, Shmuel Kivity, Shira Benor, Idit Lachover-Roth, Yuri Zeldin, Migel Stein, Ori Toker, Gamal Hassoun, Shira Bezalel-Rosenberg, Elias Toubi, Ilan Asher, Zev Sthoeger
No abstract text is available yet for this article.
October 4, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28988785/chronic-ocular-complications-of-stevens-johnson-syndrome-associated-with-causative-medications-in-korea
#8
Hyo Kyung Lee, Kyung Chul Yoon, Kyoung Yul Seo, Mayumi Ueta, Mee Kum Kim
No abstract text is available yet for this article.
October 4, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28988784/risk-of-immediate-type-allergy-to-local-anesthetics-is-overestimated-results-from-5%C3%A2-years-of-provocation-testing-in-a-danish-allergy%C3%A2-clinic
#9
Ask D Kvisselgaard, Holger F Mosbech, Sara Fransson, Lene H Garvey
BACKGROUND: Local anesthetics (LAs) are used in many health care settings and exposure during a lifetime is almost inevitable. Immediate-type allergy to LAs is considered rare among allergy experts but is commonly suspected by health care workers from other specialties, and by patients. OBJECTIVE: The main aim of this study was to investigate the incidence of immediate-type allergy to LAs in our regional allergy clinic over the 5-year period 2010 to 2014. METHODS: This was a retrospective single-center study of patients referred to a regional allergy clinic (excluding patients with perioperative reactions) with suspected immediate allergy to LAs, who had undergone subcutaneous provocation with 1 or more LAs...
October 4, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28986120/acetyl-salicylic-acid-challenge-in-children-with-hypersensitivity-reactions-to-nonsteroidal-anti-inflammatory-drugs-differentiates-between-cross-intolerant-and-selective-responders
#10
Natalia Blanca-López, Elisa Haroun-Diaz, Francisco Javier Ruano, Diana Pérez-Alzate, María Luisa Somoza, María Vázquez de la Torre Gaspar, Francisco Rivas-Ruiz, Elena García-Martin, Miguel Blanca, Gabriela Canto
BACKGROUND: Hypersensitivity reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) in children are becoming a great concern. Most studies have focused on adults, with noted discrepancies observed in the classification of hypersensitivity reactions to NSAIDs in children when compared with adults. OBJECTIVE: To phenotype a group of children with hypersensitivity reactions to NSAIDs, including paracetamol, and analyze the degree of agreement with the entities reported in adults and how they fit the proposed classifications...
October 3, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28986119/utility-of-risk-stratification-for-paclitaxel-hypersensitivity-reactions
#11
Iris M Otani, Timothy Lax, Aidan A Long, Benjamin R Slawski, Carlos A Camargo, Aleena Banerji
BACKGROUND: Hypersensitivity reactions (HSRs) are a common impediment to paclitaxel therapy. Management strategies to guide care after a paclitaxel-induced HSR are needed. OBJECTIVE: The objective was to evaluate the utility and safety of risk stratification on the basis of severity of the initial HSR. METHODS: A risk stratification pathway was developed on the basis of a retrospective review of the management and outcome of 130 patients with paclitaxel-induced HSRs at Massachusetts General Hospital...
October 3, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28974350/a-novel-2-day-desensitization-protocol-to-oral-mesalamine
#12
Christine Marie Panganiban, Deena Pourang, Shefali Anil Samant
No abstract text is available yet for this article.
September 30, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28974349/step-down-therapy-for-asthma-well-controlled-on-inhaled-corticosteroid-and-long-acting-beta-agonist-a-randomized-clinical-trial
#13
Linda Rogers, Elizabeth A Sugar, Kathryn Blake, Mario Castro, Emily Dimango, Nicola A Hanania, Kyle I Happel, Stephen P Peters, Joan Reibman, Joy Saams, W Gerald Teague, Robert A Wise, Janet T Holbrook
BACKGROUND: Stepping down therapy when asthma is well controlled on combination inhaled corticosteroids (ICSs) and long-acting beta-agonists (LABAs) is recommended, but it is not known whether lowering the ICS dose or stopping LABA is superior. OBJECTIVE: To evaluate whether step-down therapy with LABA is superior to one without; and, secondarily, to evaluate whether reducing the ICS dose while maintaining LABA is noninferior to remaining on stable-ICS/LABA. METHODS: The study was a randomized, double-masked 3-arm parallel group trial in participants aged 12 years or older...
September 30, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28970087/where-do-children-die-from-asthma-national-data-from-2003-to-2015
#14
Anna J Chen Arroyo, Christine Pal Chee, Carlos A Camargo, N Ewen Wang
No abstract text is available yet for this article.
September 29, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28970086/a-case-of-flagellate-dermatitis-after-ingestion-of-shiitake-mushrooms
#15
Natacha Santos, Pedro Morais Silva, Maria Antónia São Bráz
No abstract text is available yet for this article.
September 29, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28970085/use-of-a-disposable-valved-holding-chamber-spacer-in-a-school-based-asthma-trial
#16
James L Goodwin, Lynn B Gerald, Jennifer L H Johnson, Joe K Gerald
No abstract text is available yet for this article.
September 29, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28970084/expert-perspectives-on-management-of-moderate-to-severe-atopic-dermatitis-a-multidisciplinary-consensus-addressing-current-and-emerging-therapies
#17
REVIEW
Mark Boguniewicz, Andrew F Alexis, Lisa A Beck, Julie Block, Lawrence F Eichenfield, Luz Fonacier, Emma Guttman-Yassky, Amy S Paller, David Pariser, Jonathan I Silverberg, Mark Lebwohl
Atopic dermatitis (AD) is a common, chronic, relapsing, inflammatory skin disease that affects children and adults. Until recently, the only Food and Drug Administration-approved systemic treatment option for patients with moderate-to-severe AD was systemic steroids, which are not recommended by current guidelines and are commonly associated with disease rebound. Instead, clinicians choose from several off-label immunosuppressants, which can have serious adverse effects. A significant number of these patients go untreated...
September 29, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28970083/safety-and-allergic-reaction-profiles-of-children-undergoing-baked-milk-and-egg-challenges-a-6-year-experience-from-a-pediatric-tertiary-referral-center
#18
Mohammad Al Enezi, Gideon Lack, Adam T Fox, Katherine Anagnostou
No abstract text is available yet for this article.
September 29, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28964705/use-of-the-basophil-activation-test-may-reduce-the-need-for-drug-provocation-in-amoxicillin-clavulanic-allergy
#19
María Salas, Rubén Fernández-Santamaría, Cristobalina Mayorga, Esther Barrionuevo, Adriana Ariza, Teresa Posadas, Jose Julio Laguna, María Isabel Montañez, Noemi Molina, Tahia Diana Fernández, María José Torres
BACKGROUND: Reports of selective reactions to clavulanic acid (CLV) have increased in recent decades because of its increased prescription in combination with amoxicillin (AX) as AX-CLV. Basophil activation test (BAT) is used for diagnosing beta-lactam immediate hypersensitivity and is the only available in vitro assay for diagnosing patients with immediate hypersensitivity to CLV. However, few studies, and with limited numbers of patients have been published. OBJECTIVE: The aim of this study was to establish the sensitivity, specificity, and negativization rates of BAT to AX and CLV...
September 27, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28964704/t-cell-lymphopenia-in-22q11-2-deletion-syndrome-relationship-to-cardiac-disease
#20
Kathleen E Sullivan, T Blaine Crowley, Kelly Maurer, Elizabeth Goldmuntz, J William Gaynor, Elaine Zackai, Donna McDonald-McGinn
No abstract text is available yet for this article.
September 27, 2017: Journal of Allergy and Clinical Immunology in Practice
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