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Hyun Joo Chung, Sang Jun Lee, Ara Jang, Chae Eun Lee, Da Won Lee, Soon Chul Myung, Jin Wook Kim
This corrects the article on p. 446 in vol. 41, PMID: 36649918.
April 2024: World Journal of Men's Health
#22
JOURNAL ARTICLE
Giorgio Ivan Russo, Ramadan Saleh, Federica Finocchi, Almas Ramadhani Juma, Damayanthi Durairajanayagam, Oguzhan Kahraman, Emrullah Söğütdelen, Ioannis Sokolakis, Ranjit B Vishwakarma, Fahmi Bahar, Ahmed M Harraz, Parviz Kavoussi, Widi Atmoko, Eric Chung, Naveen Kumar, Wael Zohdy, Amarnath Rambhatla, Mohamed Arafa, Nguyen Ho Vinh Phuoc, Gianmaria Salvio, Aldo E Calogero, Tuncay Toprak, Germar-Michael Pinggera, Rossella Cannarella, Giovanni Colpi, Taha Abo-Almagd Abdel-Meguid Hamoda, Rupin Shah, Ashok Agarwal
PURPOSE: Varicocele has been associated with high seminal oxidative stress (OS), impaired semen quality, and reduced male fertility potential. However, the exact mechanism(s) underlying the development of varicocele-mediated infertility and the cause-effect relationship between varicocele and testicular dysfunction are not fully understood. The aim of this systematic review and meta-analysis (SRMA) is to investigate the impact of varicocele on testicular OS markers and sperm parameters in experimental animals with varicocele as compared to animals without varicocele...
February 7, 2024: World Journal of Men's Health
#23
JOURNAL ARTICLE
Rubén Fernández-Rodríguez, Vicente Martínez-Vizcaíno, Sara Reina-Gutiérrez, Bruno Bizzozero-Peroni, Ana Torres-Costoso, Eva Rodríguez-Gutiérrez, Valentina Díaz-Goñi, Cristina Cadenas-Sánchez
PURPOSE: Our objective was to synthesize and determine whether there are sex differences in physical function following exercise interventions in older adults. MATERIALS AND METHODS: A systematic search was conducted in four databases from inception to July 8th, 2023 searching for prospective trials that conducted exercise interventions in older adults and results for physical function were reported by sex. Pooled standardized mean differences (SMDs) with their 95% confidence intervals (CIs) were estimated using a randomeffects method...
February 7, 2024: World Journal of Men's Health
#24
JOURNAL ARTICLE
Mee Young Kim, Min Soo Jo, Sun Geum Choi, Hyong Woo Moon, Jaesung Park, Ji Youl Lee
PURPOSE: To evaluate the therapeutic effect of repeated injections of mesenchymal stem cell (MSC)-derived exosomes on the erectile dysfunction (ED) of bilateral cavernous nerve injury (BCNI) rat model and to identify potential target genes of these injections. MATERIALS AND METHODS: MSC-derived exosomes were isolated using an aqueous two-phase system. Rats were randomly assigned into four groups: Normal, BCNI, exosome once, and exosome-repeat groups. After four weeks, we measured the intracavernosal pressure (ICP)/mean arterial pressure (MAP) ratio to evaluate erectile function and examined cavernous nerve tissues for histological and molecular analyses...
February 1, 2024: World Journal of Men's Health
#25
JOURNAL ARTICLE
Ilter Alkan, Begum Durkut, Melike Ucak, Muammer Bozkurt, Halil Lutfi Canat, Ciler Celik-Ozenci
PURPOSE: To evaluate the expression of core molecular clock genes/proteins in penile cavernous tissue from healthy male subjects and to determine whether their expression has circadian variation. MATERIALS AND METHODS: Corpus cavernosum biopsy samples were obtained from 10 healthy males with penile deviation or fracture who underwent surgical intervention during the day and night. The daytime group (n=5) underwent corpus cavernosum tissue sampling during zeitgeber time (ZT) 8-12, while the nighttime group (n=5) underwent sampling during ZT 20-24...
January 29, 2024: World Journal of Men's Health
#26
JOURNAL ARTICLE
Ionel Valentin Popeneciu, Mirjam Naomi Mohr, Arne Strauß, Conrad Leitsmann, Lutz Trojan, Mathias Reichert
PURPOSE: To evaluate the morbidity, functional and oncological outcome of irreversible electroporation (IRE) as a focal therapy for prostate cancer (PCa) when used in "active surveillance (AS)" candidates refusing standard treatment options. MATERIALS AND METHODS: IRE was performed under general anaesthesia, and the transurethral catheter was removed one day after intervention in all patients. Pre- and post-interventional voiding parameters (measured by International Prostate Symptom Score Questionnaire [IPSS], uroflowmetry and post-void residue) were compared...
January 18, 2024: World Journal of Men's Health
#27
JOURNAL ARTICLE
Hao Peng, Hanlin Zhang, Sheng Xin, Hao Li, Xiaming Liu, Tao Wang, Jihong Liu, Yucong Zhang, Wen Song
PURPOSE: Erectile dysfunction (ED) is associated with several vascular disorders, but the associations between ED and vascular parameters are still unclear. MATERIALS AND METHODS: We analyzed and synthesized a comprehensive range of studies from PubMed, Web of Science, and Scopus regarding the associations between ED and the following measures: ankle-brachial index (ABI), pulse wave velocity (PWV), intima-media thickness (IMT), nitrate-mediated dilation (NMD), flow-mediated dilation (FMD), augmentation index (AI), endothelial progenitor cells (EPCs) and other vascular parameters...
January 15, 2024: World Journal of Men's Health
#28
JOURNAL ARTICLE
Tianle Zhu, Xi Liu, Peng Yang, Yukuai Ma, Pan Gao, Jingjing Gao, Hui Jiang, Xiansheng Zhang
PURPOSE: Explore the causal relationship between the gut microbiota and erectile dysfunction (ED) at phylum, class, order, family, and genus levels, and identify specific pathogenic bacteria that may be associated with the onset and progression of ED. MATERIALS AND METHODS: The genetic variation data of 196 human gut microbiota incorporated in our study came from the human gut microbiome Genome Wide Association Studies (GWAS) dataset released by the MiBioGen Consortium...
January 4, 2024: World Journal of Men's Health
#29
JOURNAL ARTICLE
Marco-Jose Rivero, Rohit Reddy, Akhil Muthigi, Raghuram Reddy, Sunwoo Han, Isildinha M Reis, Mehul Patel, Ranjith Ramasamy
PURPOSE: To evaluate patient satisfaction and symptom control in hypogonadal men transitioning from other testosterone therapies to oral testosterone undecanoate (TU). MATERIALS AND METHODS: In this open-label clinical trial, men aged 18 to 75 years with hypogonadism were switched to oral TU after a sufficient washout of previous testosterone therapies. Treatment satisfaction and symptom control were primarily measured using the 9-item Treatment Satisfaction Questionnaire for Medication (TSQM-9) and quantitative androgen deficiency in aging males (qADAM) questionnaires, respectively...
January 2, 2024: World Journal of Men's Health
#30
JOURNAL ARTICLE
Tzu Shuang Chen, Hui Ying Liu, Yin Lun Chang, Yao Chi Chuang, Yen Ta Chen, Yu Li Su, Chun Chieh Huang, Yen Ting Wu, Hung Jen Wang, Hao Lun Luo
PURPOSE: Numerous studies have produced conflicting findings regarding the efficacy of statins in prostate cancer treatment. Our objective was to examine the correlation between statin usage and clinical outcomes in Taiwanese men with de novo metastatic prostate cancer. MATERIALS AND METHODS: We identified patients diagnosed with de novo metastatic prostate cancer from the Chang Gung Research Database spanning the years 2007 to 2020. To minimize confounding bias, we employed the inverse probability of treatment weighting (IPTW) method...
January 2, 2024: World Journal of Men's Health
#31
JOURNAL ARTICLE
Daoyuan Hu, Yunlong Ge, Yuhang Xi, Jialiang Chen, Hua Wang, Chi Zhang, Yubin Cui, Lizhao He, Ying Su, Jun Chen, Cheng Hu, Hengjun Xiao
PURPOSE: The poor retention and ambiguous differentiation of stem cells (SCs) within corpus cavernosum (CC) limit the cell application in erectile dysfunction (ED). Herein, the effects and mechanism of microRNA-145 (miR-145) gene modification on modulating the traits and fate of bone marrow-derived mesenchymal stem cells (BMSCs) were investigated. MATERIALS AND METHODS: The effects of miR-145 on cell apoptosis, proliferation, migration, and differentiation were determined by flow cytometry, cell counting kit-8, transwell assays and myogenic induction...
January 2, 2024: World Journal of Men's Health
#32
JOURNAL ARTICLE
Rossella Cannarella, Rupin Shah, Ramadan Saleh, Florence Boitrelle, Taha Abo-Almagd Abdel-Meguid Hamoda, Rajender Singh, Gianmaria Salvio, Tuncay Toprak, Marco Falcone, Murat Gul, Fotios Dimitriadis, Amarnath Rambhatla, Giorgio I Russo, Edmund Ko, Armand Zini, Parviz Kavoussi, Nguyen Ho Vinh Phuoc, Hussein Kandil, Ramy Abou Ghayda, Ponco Birowo, Nazim Gherabi, Erman Ceyhan, Jie Dong, Vineet Malhotra, Damayanthi Durairajanayagam, Bircan Kolbasi, Fahmi Bahar, Gokhan Calik, Selahittin Çayan, Germar-Michael Pinggera, Aldo E Calogero, Osvaldo Rajmil, Taymour Mostafa, Widi Atmoko, Ahmed M Harraz, Tan V Le, Jean de la Rosette, Lukman Hakim, Edoardo Pescatori, Oleg Sergeyev, Ayman Rashed, Pallavi Saini, Ashok Agarwal
PURPOSE: Varicoceles can be a source of elevated seminal oxidative stress (OS) and sperm DNA fragmentation (SDF). However, it remains unclear whether varicocele repair (VR) could reduce these parameters. This systematic review and meta-analysis (SRMA) aims to investigate the impact of VR on SDF and seminal malondialdehyde (MDA). MATERIALS AND METHODS: A literature search was performed in Scopus, PubMed, Ovid, Embase, and Cochrane databases. This SRMA included randomized controlled trials and observational studies reporting the pre- and postoperative levels of SDF and seminal OS in infertile men with clinical varicocele that underwent VR...
January 2, 2024: World Journal of Men's Health
#33
JOURNAL ARTICLE
Juan Víctor Ariel Franco, Leonel Fabrizio Trivisonno, Nadia Sgarbossa, Gustavo Ariel Alvez, Cecilia Fieiras, Camila Micaela Escobar Liquitay, Jae Hung Jung
PURPOSE: To assess the effects of Serenoa repens in the treatment of men with lower urinary tract symptoms (LUTS) consistent with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: We performed a comprehensive search using multiple databases up to September 2022 with no language or publication status restrictions. We included parallel-group randomized controlled trials of participants with BPH who were treated with Serenoa repens or placebo/no treatment...
January 2, 2024: World Journal of Men's Health
#34
JOURNAL ARTICLE
Jong Hyun Pyun, Nak-Hoon Son, Young Hwii Ko, Sang Won Kim, Hoseob Kim, Yoon-Jong Bae
PURPOSE: To investigate the long-term effects of taking 5-alpha reductase inhibitors (5ARIs) on the development of bladder cancer (BC) and the implementation of radical cystectomy (RC), a standard procedure for advanced BC. MATERIALS AND METHODS: From the National Health Insurance Sharing Service database, males aged over 40 years who underwent serum prostate-specific antigen testing from 2006 through 2017 were identified, which is required for the prescription of 5ARIs...
January 2, 2024: World Journal of Men's Health
#35
JOURNAL ARTICLE
Arturo Lo Giudice, Maria Giovanna Asmundo, Sebastiano Cimino, Giuseppe Morgia, Andrea Cocci, Marco Falcone, Ioannis Sokolakis, Paolo Capogrosso, Afonso Morgado, Giorgio Ivan Russo
PURPOSE: Augmented adiposity may negatively impact sexual sphere through its metabolic effects and its detrimental impact on reproductive hormones. Moreover, a dysregulated metabolic pathway may promote apoptosis among spermatogenic cells. Based on these premises, a relation between weights loss and ameliorate semen parameters seems beneficial. To investigate if physical activity may affect semen parameters and fertility rate, a systematic literature search on major dataset has been performed...
January 2, 2024: World Journal of Men's Health
#36
REVIEW
Murat Gül, Giorgio Ivan Russo, Hussein Kandil, Florence Boitrelle, Ramadan Saleh, Eric Chung, Parviz Kavoussi, Taymour Mostafa, Rupin Shah, Ashok Agarwal
There have been many significant scientific advances in the diagnostics and treatment modalities in the field of male infertility in recent decades. Examples of these include assisted reproductive technologies, sperm selection techniques for intracytoplasmic sperm injection, surgical procedures for sperm retrieval, and novel tests of sperm function. However, there is certainly a need for new developments in this field. In this review, we discuss advances in the management of male infertility, such as seminal oxidative stress testing, sperm DNA fragmentation testing, genetic and epigenetic tests, genetic manipulations, artificial intelligence, personalized medicine, and telemedicine...
January 2, 2024: World Journal of Men's Health
#37
JOURNAL ARTICLE
Longlong Fu, Fang Fang, Ying Guo, Jing Ma, Shusong Wang, Yiqun Gu, Xiangming Yan, Wenhong Lu, Ying Liu
PURPOSE: This study aimed to identify the altered pathways and genes associated with freezing damage in human sperm during cryopreservation by multiomics analysis. MATERIALS AND METHODS: Fifteen fresh human semen samples were collected for transcriptomic analysis, and another 5 fresh human semen samples were obtained for metabolomic analysis. For each semen sample, 1 mL was cryopreserved, and another 1 mL was left untreated for paired design. The results were then combined with previously published proteomic results to identify key genes/pathways...
January 2, 2024: World Journal of Men's Health
#38
JOURNAL ARTICLE
Dong Jin Park, Tae Gyun Kwon, Jae Young Park, Jae Young Joung, Hong Koo Ha, Seong Soo Jeon, Sung-Hoo Hong, Sungchan Park, Seung Hwan Lee, Jin Seon Cho, Sung-Woo Park, Se Yun Kwon, Jung Ki Jo, Hong Seok Park, Sang-Cheol Lee, Dong Deuk Kwon, Sun Il Kim, Sang Hyun Park, Soodong Kim, Chang Wook Jeong, Cheol Kwak, Seock Hwan Choi
PURPOSE: This study aimed to compare the short-term outcomes and safety profiles of androgen-deprivation therapy (ADT)+abiraterone/prednisone with those of ADT+docetaxel in patients with de novo metastatic hormone-sensitive prostate cancer (mHSPC). MATERIALS AND METHODS: A web-based database system was established to collect prospective cohort data for patients with mHSPC in Korea. From May 2019 to November 2022, 928 patients with mHSPC from 15 institutions were enrolled...
January 2, 2024: World Journal of Men's Health
#39
JOURNAL ARTICLE
Simone Cilio, Giuseppe Fallara, Maria Teresa Lupo Stanghellini, Fabio Ciceri, Francesco Montorsi, Francesca Lunghi, Andrea Salonia
PURPOSE: Hydroxyurea (HU) is a cytoreductive agent used as standard treatment option for sickle cell anaemia/disease (SCD), essential thrombocythemia (ET), and polycythaemia vera (PV). Despite its overall good safety profile, its use also in relatively young patients raises an interest on its potential impact on spermatogenesis. To perform a systematic review of all published articles investigating fertility in male patients affected by SCD, ET, and PV and treated with HU. Two paradigmatic case reports of patients affected by PV and ET, respectively, have been also reported...
January 2, 2024: World Journal of Men's Health
#40
JOURNAL ARTICLE
Walid El Ansari, Mohamed Arafa, Merilyn Lock, Rupin Shah, Ashok Agarwal
PURPOSE: This is the first study to assess the impact of an online microsurgical testicular sperm extraction (mTESE) masterclass. We: 1) describe the masterclass's scientific content; 2) appraise the participants' acquisition of knowledge; 3) gauge whether the extent of improvement of the participants' knowledge/skills was influenced by demographic/professional attributes; and 4) evaluate the participants' satisfaction. MATERIALS AND METHODS: This masterclass comprised five didactic lectures followed by 4 case discussions...
January 2, 2024: World Journal of Men's Health
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