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World Journal of Men's Health

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https://www.readbyqxmd.com/read/29774671/is-it-worth-treating-non-bothering-nocturia-results-of-a-multicenter-prospective-observational-study
#1
Kwangsung Park, Hyoung Keun Park, Sae Woong Kim, Dae Yul Yang, Jong Kwan Park, Hyun Jun Park, Ki Hak Moon, Du Geon Moon, Kweon Sik Min, Hwancheol Son, Sung Won Lee, Jae Seog Hyun, Woo Suk Choi, Sang Kuk Yang
PURPOSE: The purpose of this study was to evaluate the efficacy of treatment in patients with non-bothering nocturia. MATERIALS AND METHODS: In this prospective multicenter study, patients who visited hospitals for treatment of voiding symptoms were enrolled. Inclusion criteria were: 1) men >45 years, and 2) nocturia ≥2 confirmed by a three-day voiding diary. Subjects were divided into non-bothering and bothering groups based on International Consultation on Incontinence Questionnaire Nocturia (ICIQ-N) question 2b...
May 17, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29774670/corrigendum-improvement-of-persistent-detrusor-overactivity-through-treatment-with-a-phytotherapeutic-agent-wsy-1075-after-relief-of-bladder-outlet-obstruction
#2
Su Jin Kim, Seung Hwan Jeon, Eun Bi Kwon, Hyun Cheol Jeong, Sae Woong Choi, Woong Jin Bae, Hyuk Jin Cho, U Syn Ha, Sung Hoo Hong, Ji Youl Lee, Sung Yeoun Hwang, Sae Woong Kim
This corrects the article on p. 153 in vol. 36, PMID: 29076300.
May 16, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29774669/obstructive-sleep-apnea-and-testosterone-deficiency
#3
REVIEW
Sung Dong Kim, Kyu Sup Cho
Obstructive sleep apnea (OSA) is a common disorder characterized by intermittent hypoxia and sleep fragmentation. OSA in middle-aged men is often associated with decreased testosterone secretion, together with obesity and aging. Although OSA treatment does not reliably increase testosterone levels in most studies, OSA treatment with testosterone replacement therapy (TRT) may not only improve hypogonadism, but can also alleviate erectile/sexual dysfunction. However, because TRT may exacerbate OSA in some patients, patients should be asked about OSA symptoms before and after starting TRT...
May 16, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29774668/varicocele-and-testicular-pain-a-review
#4
REVIEW
Sunghyun Paick, Woo Suk Choi
Varicocele is the dilatation of the scrotal portion of pampiniform plexus and the internal spermatic venous system. About 15% of men suffer from scrotal varicocele and 2% to 10% of them complain of pain. The probable mechanisms for pain include compression of the surrounding neural fibers by the dilated venous complex, elevated testicular temperature, increased venous pressure, hypoxia, oxidative stress, hormonal imbalances, and the reflux of toxic metabolites of adrenal or renal origin. Testicular pain associated with varicoceles is typically described as a dull, aching, or throbbing pain in the testicle, scrotum, or groin; rarely, it can be acute, sharp, or stabbing...
May 16, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29756419/growth-hormone-and-aging-updated-review
#5
REVIEW
Andrzej Bartke
Role of growth hormone (GH) in mammalian aging is actively explored in clinical, epidemiological, and experimental studies. The age-related decline in GH levels is variously interpreted as a symptom of neuroendocrine aging, as one of causes of altered body composition and other unwelcome symptoms of aging, or as a mechanism of natural protection from cancer and other chronic diseases. Absence of GH signals due to mutations affecting anterior pituitary development, GH secretion, or GH receptors produces an impressive extension of longevity in laboratory mice...
May 11, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29756418/statins-and-erectile-dysfunction
#6
EDITORIAL
John B Kostis, Jeanne M Dobrzynski
No abstract text is available yet for this article.
May 11, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29756417/dehydroepiandrosterone-and-erectile-function-a-review
#7
REVIEW
Ahmed I El-Sakka
To review the contemporary knowledge regarding the dehydroepiandrosterone and erectile function. Medline was reviewed for English-language journal articles spanning the time between January 1990 and December 2017, using the terms 'erectile function', 'dehydroepiandrosterone'. We used Journal Articles and review articles that found to be relevant to the purpose of this review. Criteria included all pertinent review articles, randomized controlled trials with tight methodological design, cohort studies and retrospective analyses...
May 11, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29756416/testosterone-and-sarcopenia
#8
REVIEW
Myung Jun Shin, Yun Kyung Jeon, In Joo Kim
Aging affects metabolism, leading to physiological and functional impairments, and is also related to changes in body composition, including reduced skeletal muscle mass and increased body fat. These changes are correlated with the pathophysiology of sarcopenia, which is defined as age-related loss of skeletal muscle mass and strength. Low testosterone levels are associated with unfavorable body composition changes, and sex hormones decrease with aging. Androgen deficiency, along with lack of exercise and poor nutrition, may be among the modifiable contributors to sarcopenia...
May 11, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29756415/the-expression-of-androgen-receptor-and-its-variants-in-human-prostate-cancer-tissue-according-to-disease-status-and-its-prognostic-significance
#9
Sung Woo Park, Jung Hee Kim, Hyun Jung Lee, Dong Hoon Shin, Sang Don Lee, Sik Yoon
PURPOSE: To evaluate changes in the expression of androgen receptor (AR) and its variants (ARVs) in human prostate cancer (PCa) tissues according to disease status, and its prognostic significance following radical prostatectomy (RP). MATERIALS AND METHODS: A total of 282 PCa cases were evaluated, which included 252 localized PCa, 8 metastatic castration resistant prostate cancer (CRPC), and 22 benign prostatic hyperplasia (BPH) cases. Samples were collected from patients who underwent RP or transurethral resection and were stored in ethically approved tissue banks...
April 16, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29623703/penile-reconstructive-surgery-in-peyronie-disease-challenges-in-restoring-normal-penis-size-shape-and-function
#10
REVIEW
Eric Chung
PURPOSE: To provide an overview of current approaches to penile reconstructive surgery in Peyronie disease (PD), and to discuss the challenges in restoring normal penile size and function. METHODS: A systematic literature search was conducted to identify the published literature relevant to PD and penile reconstructive surgery. A summary of the published guidelines from major organisations is included in this review paper. DISCUSSION: Penile plication is simple and minimally invasive, and tends to preserve potency in most patients...
March 29, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29623701/let-s-take-advantage-of-mixtures-of-bupivacaine-or-ropivacaine-in-urologic-inguinal-and-scrotal-surgery
#11
Yu Seob Shin, A Ram Doo, Jong Kwan Park
No abstract text is available yet for this article.
March 22, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29623700/the-relationship-between-neonatal-circumcision-urinary-tract-infection-and-health
#12
REVIEW
Michael L Eisenberg, Deron Galusha, William A Kennedy, Mark R Cullen
The risk-benefit profile of neonatal circumcision is not clear. Most studies have focused on urinary tract infections but other health sequelae have not been evaluated. While evidence supports benefits of circumcision, a lack of randomized trials has been cited as a weakness. National guidelines provide mixed recommendations regarding neonatal circumcision. We review the weight of evidence and utilize current statistical methodology on observational data to examine the risks and benefits of neonatal circumcision...
March 22, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29623698/shifting-the-paradigm-of-testosterone-replacement-therapy-in-prostate-cancer
#13
REVIEW
Michael A Bell, Jeffrey D Campbell, Gregory Joice, Nikolai A Sopko, Arthur L Burnett
Historically, testosterone and prostate cancer have been demonstrated to have a positive association leading providers to forgo testosterone replacement therapy (TRT) in men with concurrent histories of hypogonadism and prostate cancer. This paradigm has been gradually shifting with our evolving understanding of the relationship between testosterone and prostate cancer and the gaining popularity of the saturation model. Newer data suggests improved quality of life for men with hypogonadism after TRT leading to a more tempered view of the effects of this treatment and its risk in prostate cancer...
March 22, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29623697/efficacy-and-safety-of-a-mixed-extract-of-trigonella-foenum-graecum-seed-and-lespedeza-cuneata-in-the-treatment-of-testosterone-deficiency-syndrome-a-randomized-double-blind-placebo-controlled-clinical-trial
#14
Hyun Jun Park, Kyeong Soo Lee, Eun Kyoung Lee, Nam Cheol Park
PURPOSE: The aim of this study was to investigate the efficacy and safety of a mixed extract of Trigonella foenum-graecum seed and Lespedeza cuneata (TFGL) for the treatment of testosterone deficiency syndrome (TDS). MATERIALS AND METHODS: Patients were instructed to take a placebo or 200 mg TFGL capsule twice per day for 8 weeks. The primary efficacy variable was the change from baseline in the Aging Males' Symptoms scale (AMS), as well as levels of serum total and free testosterone...
March 22, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29706035/silencing-histone-deacetylase-7-alleviates-transforming-growth-factor-%C3%AE-1-induced-profibrotic-responses-in-fibroblasts-derived-from-peyronie-s-plaque
#15
Dong Hyuk Kang, Guo Nan Yin, Min Ji Choi, Kang Moon Song, Kalyan Ghatak, Nguyen Nhat Minh, Mi Hye Kwon, Do Hwan Seong, Ji Kan Ryu, Jun Kyu Suh
PURPOSE: Epigenetic modifications, such as histone acetylation/deacetylation and DNA methylation, play a crucial role in the pathogenesis of inflammatory disorders and fibrotic diseases. The aim of this study was to study the differential gene expression of histone deacetylases (HDACs) in fibroblasts isolated from plaque tissue of Peyronie's disease (PD) or normal tunica albuginea (TA) and to examine the anti-fibrotic effect of small interfering RNA (siRNA)-mediated silencing of HDAC7 in fibroblasts derived from human PD plaque...
May 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29706034/emerging-evidences-in-the-long-standing-controversy-regarding-testosterone-replacement-therapy-and-cardiovascular-events
#16
REVIEW
Jonathan Clavell-Hernández, Run Wang
The increasing rate of late-onset hypogonadism has led to an exceptional growth in the use of testosterone therapy (TTh). Even though TTh has been used for more than 70 years, there has been an emerging controversy in the past several years regarding its safety due to a suggested increased risk of cardiovascular (CV) disease among its users. Given the growing prevalence of testosterone deficiency in our population and the increased use of TTh, the goal of this review is to present the history and emerging evidence in regards to this controversy...
May 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29623702/testosterone-replacement-muscle-strength-and-physical-function
#17
REVIEW
You Seon Nam, Gyeongsil Lee, Jae Moon Yun, Belong Cho
Muscle strength and physical function decrease in older men, as do testosterone levels. Nonetheless, the effects of testosterone replacement therapy on muscle strength and physical function remain inconclusive and equivocal. We conducted a rapid systematic review, the results of which showed that testosterone replacement does not affect muscle strength (measured by hand grip strength and leg muscle strength), although it may increase physical function (measured by the 6-minute walk test, Physical Activity Scale for the Elderly score, and other physical performance tests)...
May 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29623699/current-issues-in-adolescent-varicocele-pediatric-urological-perspectives
#18
REVIEW
Jae Min Chung, Sang Don Lee
While varicocele is the most common cause of surgically correctable infertility in adult males, with repair resulting in improved semen parameters in 60% to 80% of men and a higher likelihood of conception in up to 60% of men, the rationale for varicocele repair in the pediatric population is less clear. Additionally, prepubertal varicoceles are much less common and their management is controversial. Adolescents with a varicocele are often in the midst of a progressive disease process. Despite the high prevalence of varicocele and its association with progressive disease processes, the indications for adolescent varicocele repair and the effects thereof on paternity have been persistently challenging to study...
May 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29076300/improvement-of-persistent-detrusor-overactivity-through-treatment-with-a-phytotherapeutic-agent-wsy-1075-after-relief-of-bladder-outlet-obstruction
#19
Su Jin Kim, Seung Hwan Jeon, Eun Bi Kwon, Hyun Cheol Jeong, Sae Woong Choi, Woong Jin Bae, Hyuk Jin Cho, U Syn Ha, Sung Hoo Hong, Ji Youl Lee, Sung Yeoun Hwang, Sae Woong Kim
PURPOSE: Many patients with benign prostatic hyperplasia need treatment for remaining storage symptoms after surgery. Therefore, we evaluated the effect of the phytotherapeutic agent WSY-1075 on persistent detrusor overactivity (DO) after the relief of bladder outlet obstruction (BOO). MATERIALS AND METHODS: Rats were assigned to 3 groups: control (n=6), persistent DO (n=6), and persistent DO treated with the phytotherapeutic agent WSY-1075 (n=6). Persistent DO after relief of partial BOO was generated in the rat model, and 6 of the rats with this condition were orally administered WSY-1075...
May 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29623696/sperm-bank-from-laboratory-to-patient
#20
EDITORIAL
Nam Cheol Park
No abstract text is available yet for this article.
February 7, 2018: World Journal of Men's Health
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