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Pathogens and Disease

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https://www.readbyqxmd.com/read/28204474/recombinant-protein-cpsit_0846-induces-protective-immunity-against-chlamydia-psittaci-infection-in-balb-c-mice
#1
O Ran, M X Liang, J Yu, M J Yu, Y Song, Y M Wu
No abstract text is available yet for this article.
February 15, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28204467/the-surface-displayed-chaperones-groel-and-dnak-of-mycoplasma-pneumoniae-interact-with-human-plasminogen-and-components-of-the-extracellular-matrix
#2
Lisa Hagemann, Anne Gründel, Enno Jacobs, Roger Dumke
No abstract text is available yet for this article.
February 15, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28175297/borrelia-primed-and-infected-mice-deficient-of-interleukin-17-develop-arthritis-after-neutralization-of-gamma-interferon
#3
Joseph Kuo, Thomas F Warner, Ronald F Schell
No abstract text is available yet for this article.
February 8, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28175294/mirnas-that-associate-with-conjunctival-inflammation-and-ocular-chlamydia-trachomatis-infection-do-not-predict-progressive-disease
#4
Tamsyn Derrick, Athumani M Ramadhani, Karim Mtengai, Patrick Massae, Matthew J Burton, Martin J Holland
No abstract text is available yet for this article.
February 8, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28175285/the-sum-of-all-defenses-tolerance-resistance
#5
Brooke A Napier, Denise M Monack
No abstract text is available yet for this article.
February 8, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28175274/the-effects-of-cpg-odns-and-chitosan-adjuvants-on-the-elicitation-of-immune-responses-induced-by-the-hiv-1-tat-based-candidate-vaccines-in-mice
#6
Samira Alipour, Atiyeh Mahdavi, Asghar Abdoli
No abstract text is available yet for this article.
February 8, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28158586/antimicrobial-activity-of-lactobacillus-salivarius-and-lactobacillus-fermentum-against-staphylococcus-aureus
#7
Mi-Sun Kang, Hae-Soon Lim, Jong-Suk Oh, You-Jin Lim, Karin Wuertz-Kozak, Janette M Harro, Mark E Shirtliff, Yvonne Achermann
No abstract text is available yet for this article.
February 2, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28158541/cholesterol-uptake-in-the-mouse-aorta-increases-during-chlamydia-pneumoniae-infection
#8
Marie Edvinsson, Jonas Tallkvist, Christina Nyström-Rosander, Nils-Gunnar Ilbäck
No abstract text is available yet for this article.
February 2, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28158534/neisserial-surface-lipoproteins-structure-function-and-biogenesis
#9
Yogesh Hooda, Hyejin E Shin, Thomas J Bateman, Trevor F Moraes
No abstract text is available yet for this article.
February 2, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28158464/activation-dependent-modulation-of-streptococcus-pneumoniae-mediated-death-in-human-lymphocytes
#10
Kristina M Grayson, Lance K Blevins, Melissa B Oliver, David Ornelles, W Edward Swords, Martha A Alexander-Miller
No abstract text is available yet for this article.
February 2, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28158456/the-proline-residue-at-position-319-of-bvgs-is-essential-for-bvgas-activation-in-bordetella-pertussis
#11
Yukihiro Hiramatsu, Shuji Yoshino, Yoshiko Yamamura, Nao Otsuka, Keigo Shibayama, Mineo Watanabe, Kazunari Kamachi
No abstract text is available yet for this article.
February 2, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28158404/escherichia-coli-diseases-in-latin-america-a-one-health-multidisciplinary-approach
#12
Alfredo G Torres
No abstract text is available yet for this article.
February 2, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28115360/saccharomyces-boulardii-administration-can-inhibit-the-formation-of-gastric-lymphoid-follicles-induced-by-helicobacter-suis-infection
#13
Lin Yang, Zi-Bin Tian, Ya-Nan Yu, Cui-Ping Zhang, Xiao-Yu Li, Tao Mao, Xue Jing, Wen-Jun Zhao, Xue-Li Ding, Ruo-Ming Yang, Shuai-Qing Zhang
Helicobacter suis has a greater tendency to induce gastric mucosa-associated lymphoid tissue (MALT) lymphoma compared with other Helicobacter species in humans and animals. Saccharomyces (S.) boulardii has been established as an adjunct to Helicobacter pylori eradication treatment, but the effect of S. boulardii administration alone on Helicobacter infection remains unclear. Here, we found that S. boulardii administration effectively decreased the bacterial load of Helicobacter suis and inhibited the formation of lymphoid follicles in the stomach post-infection...
January 22, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28115359/involvement-of-matrix-metalloproteinases-and-their-inhibitors-in-endometrial-extracellular-matrix-turnover-in-chlamydia-trachomatis-infected-recurrent-spontaneous-aborters
#14
Namita Singh, Priya Prasad, Banashree Das, Sangita Rastogi
Mechanism underlying Chlamydia trachomatis disease pathology is not completely understood. It was hypothesized that dysregulation of extracellular matrix by matrix metalloproteinases (MMPs) might be involved in sequelae of events leading to abortion in C. trachomatis-infected women. Hence present study was undertaken to elucidate the expression of MMP-2/ MMP-9/ TIMP-1/ TIMP-3 in infected recurrent spontaneous aborters (RSA) and simultaneously ascertain effect of few cytokines (TNF-α, TGF-β1, TGF-β2)/ cyclooxygenase-2 (Cox-2) on MMPs...
January 22, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28104617/staphylococcus-aureus-pathogenesis-in-diverse-host-environments
#15
Divya Balasubramanian, Lamia Harper, Bo Shopsin, Victor J Torres
Staphylococcus aureus (S. aureus) is an eminent human pathogen that can colonize the human host and cause severe, life-threatening illnesses. This bacterium can reside in and infect a wide range of host tissues, ranging from superficial surfaces like the skin to deeper tissues such as in the gastrointestinal tract, heart and bones. Due to its multifaceted lifestyle, S. aureus uses complex regulatory networks to sense diverse signals that enable it to adapt to different environments and modulate virulence. In this mini-review, we explore well-characterized environmental and host cues that S...
January 18, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28104616/sequential-colonization-of-periodontal-pathogens-in-induction-of-periodontal-disease-and-atherosclerosis-in-ldlrnull-mice
#16
Sasanka S Chukkapalli, Meena Easwaran, Mercedes F Rivera-Kweh, Irina M Velsko, Sriram Ambadapadi, Jiayin Dai, Hannu Larjava, Alexandra R Lucas, Lakshmyya Kesavalu
Periodontal disease (PD) and atherosclerotic vascular disease (ASVD) are both chronic inflammatory diseases with a polymicrobial etiology and have been epidemiologically associated. The purpose is to examine whether periodontal bacteria that infect the periodontium, can also infect vascular tissues and enhance pre-existing early aortic atherosclerotic lesions in LDLR(null) mice. Mice were orally infected with intermediate bacterial colonizer Fusobacterium nucleatum for the first 12 weeks followed by late bacterial colonizers (Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia) for the remaining 12 weeks mimicking the human oral microbiota ecological colonization...
January 18, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28087650/simkania-negevensis-may-produce-long-lasting-infections-in-human-pneumocytes-and-endometrial-cells
#17
Manon Vouga, David Baud, Gilbert Greub
Simkania negevensis is a novel Chlamydia-related bacterium and the founding member of the Simkaniaceae family within the Chlamydiales order. Little is known about the biology and pathogenesis of this bacterium. So far, S. negevensis has been considered as an amoebal symbiont, but its natural host remains unknown. Moreover, evidence of human exposition has been reported worldwide and an association with pneumonia and bronchiolitis is suspected. Here, we evaluated the ability of S. negevensis to replicate in potential environmental reservoirs, namely amoebae and arthropods, as well as in mammalian cells (Vero cells, pneumocytes and endometrial cells) and further evaluated the characteristics of its replicative vacuole...
January 12, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28087649/identification-of-unique-essential-proteins-from-a-m-tuberculosis-f15-lam4-kzn-phage-secretome-library
#18
Thamsanqa Emmanuel Chiliza, Manormoney Pillay, Balakrishna Pillay
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis disease (TB), the leading cause of death from bacterial infection worldwide. Although treatable, the resurgence of multi- and extensively-drug resistance TB is a major setback for the fight against TB globally. Consequently, there is an urgent need for new Mtb derived biomarkers for use in the design of new drugs and rapid point-of-care diagnostic or prognostic tools for management of TB transmission. Therefore, the present study aimed to identify unique Mtb secreted proteins from the extensively drug resistant Mtb F15/LAM4/KZN phage secretome library...
January 12, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28087648/effect-of-in-vivo-neutralisation-of-tumor-necrosis-factor-alpha-on-the-efficacy-of-antibiotic-treatment-in-systemic-salmonella-enterica-infections
#19
Omar Rossi, Andrew J Grant, Pietro Mastroeni
Immunity can co-operate with antibiotics, but can also antagonize drug efficacy by segregating the bacteria to areas of the body that are less accessible to antimicrobials, and by selecting for subpopulations with low division rates that are often difficult to eradicate. We studied the effect of an anti-inflammatory/immunosuppressive anti-TNFα treatment, which accelerates bacterial growth in the tissues and inhibits or reverses the formation of granulomas, on the efficacy of ampicillin and ciprofloxacin during a systemic Salmonella enterica infection of the mouse...
January 12, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28057727/indoleamine-2-3-dioxygenase-activity-is-associated-with-regulatory-t-cell-response-in-acute-puumala-hantavirus-infection
#20
Tuisku-Tuulia Koivula, Anni Tuulasvaara, Iivo Hetemäki, Mikko Hurme, Satu Mäkelä, Jukka Mustonen, Antti Vaheri, T Petteri Arstila
High indoleamine 2,3-dioxygenase (IDO) activity is associated with clinically severe acute infection caused by Puumala hantavirus. The immunoregulatory effects of IDO can be mediated either through metabolic control of effector T cells, caused by depletion of the essential amino acid tryptophan, or intercellular signaling and activation of regulatory T cell responses. Here we have studied 24 patients with acute PUUV infection to distinguish between these possibilities. Maximum IDO activity showed a significant positive correlation with FOXP3 expression levels in regulatory T cells, a quantitative surrogate marker for suppressive capability...
January 5, 2017: Pathogens and Disease
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