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Journal of Diabetes and Metabolic Disorders

Tejaskumar R Kalaria, Habibunnisha B Sirajwala, Mukesh G Gohel
BACKGROUND: Glycation of serum proteins has been proposed as an important mechanism of complications of diabetes but whether there are differences in glycation of different serum proteins and whether it has any correlation with development of microvascular complications has not been studied in depth. This study aimed to assess level of serum fructosamine, glycated albumin and glycated β-lipoprotein in type 2 diabetes mellitus patients with and without microvascular complications and to find out their correlation with diabetes complications...
2016: Journal of Diabetes and Metabolic Disorders
Maryam Ghodsi, Bagher Larijani, Abbass Ali Keshtkar, Ensieh Nasli-Esfahani, Sudabeh Alatab, Mohammad Reza Mohajeri-Tehrani
Many studies have shown that change in metabolism caused by diabetes can influence the bone metabolism in a way that quality and strength of bone is decreased. A 6 times and 2 times increased risk of fracture is reported in patients with type 1 and type 2 diabetes, respectively. There are several mechanisms by which diabetes can affect the bone. The fact that some of these mechanisms are acting in opposite ways opens the door for debate on pathways by which diabetes affects the bones. On the other hand, bone is not a simple organ that only get influence from other organs, but it is an endocrine organ that by secreting the agents such as osteocalcin, adiponectin and visfatin which can affect the insulin sensitivity and metabolism...
2016: Journal of Diabetes and Metabolic Disorders
Zhila Maghbooli, Parisa Shabani, Sattar Gorgani-Firuzjaee, Arash Hossein-Nezhad
BACKGROUND: Global epidemic of diabetes is a serious health care concern because of its complications and consequently reduced life expectancy and increased morbidity. However, the bone turnover and thus bone health may be affected or even compromised by diabetes and its complications. The aim of this study was to assess whether bone turnover markers are associated with diabetes micro-vascular complications. METHODS: A total of 204 type 2 diabetes patients (104 patients with diabetic micro-vascular complications (retinopathy and/or nephropathy) as a case group and 100 patients without retinopathy and/or nephropathy) as a control group were recruited in this case-control study...
2016: Journal of Diabetes and Metabolic Disorders
Elamin I E Abdelgadir, Mohamed M Hassanein, Alaaeldin M K Bashier, Sulaf Abdelaziz, Salwa Baki, Asma Chadli, Sara Askaoui, El Ansari Nawal, Ines S Slim, El Mghari Ghizlane, Khadija Hafidh, Fatheya Alawadi
BACKGROUND: 1.7 billion Muslims worldwide obey divine commands of fasting for a month. This may increase the probability of the acute complications of diabetes during the fasting period. DESIGN AND METHODS: We primarily aimed to compare the incidences and duration of Diabetic ketoacidosis (DKA) admissions during Ramadan compared to the month before (Shaaban) and the month after (Shawal) as well as the average pre-Ramadan six months' admissions. Our secondary objective was to assess the different incidence of DKA between Ramadan and the other months regarding precipitating factors, fasting practices in people admitted with DKA and gender differences...
2016: Journal of Diabetes and Metabolic Disorders
Ozra Tabatabaei-Malazy, Amir Ramezani, Rasha Atlasi, Bagher Larijani, Mohammad Abdollahi
BACKGROUND: Scientometric analysis is increasingly used for research assessment. We aimed to perform a scientometric analysis of research productivity in field of antioxidative hypoglycemic herbal medicine and diabetes. METHODS: Some of search terms were "type 2 diabetes", "antioxidant", "herb", "phytotherapy", "ethnopharmacology", "Chinese medicine", "traditional medicine", in Scopus web databases until January 2015, and limited to human. The collected data were used to generate the specific features such as publication year, main journal in the field, citation, subject area, and co-authorship network of authors and institutes...
2016: Journal of Diabetes and Metabolic Disorders
Hamid Najafipour, Mostafa Shokoohi, Gholamreza Yousefzadeh, Behzad Sarvar Azimzadeh, Gholamreza Moshtaghi Kashanian, Mohamad Mehdi Bagheri, Ali Mirzazadeh
BACKGROUND: Despite the importance of identifying and screening dyslipidemia to prevent coronary artery diseases CAD(Coronary Artery Disease), little information is available on dyslipidemia in our large area. So the present study aimed to assess the management status of lipid abnormalities and its association with other CAD risk factors in an urban population of southeast of Iran. METHODS: This cross-sectional study was a part of the Kerman coronary artery disease risk factor study KERCADRS (Kerman coronary artery disease risk study) as a population-based, epidemiological research among 5900 individuals aged 15 to 75 years who were residents of Kerman city, the largest city in Southeast of Iran...
2016: Journal of Diabetes and Metabolic Disorders
Claudia Boucher-Berry, Elaine A Parton, Ramin Alemzadeh
BACKGROUND: While higher total daily dose (TDD) of insulin has been associated with excess weight gain on insulin pump therapy, the role of higher total basal dose (TBD) of insulin on weight gain has not been studied. We evaluated the impact of higher TBD on weight gain in relationship to glycosylated hemoglobin (HbA1c), hypoglycemic episodes, and change in body mass index (BMI) z score in a group of pediatric patients with type 1 diabetes mellitus (T1DM). METHODS: One-year data from 91 (54 Female/37 Male) patients (2...
2016: Journal of Diabetes and Metabolic Disorders
Kwame Yeboah, Eric Kyei-Baafour, Daniel A Antwi, Henry Asare-Anane, Ben Gyan, Albert G B Amoah
BACKGROUND: Impaired angiogenesis is amongst the underlining mechanisms of organ damage in diabetes and hypertensive patients. In diabetes and hypertensive patients without proteinuria and overt CVDs, we studied the levels of angiogenic growth factors, angiopoietin (Ang)-1, Ang-2 and vascular endothelial growth factor (VEGF), and the relationship between these angiogenic growth factors and renal function, measured as estimated glomerular filtration rate (eGFR). METHOD: In a case control design, 107 type 2 diabetes (T2DM) patients and 93 non-diabetes controls were recruited into the study...
2016: Journal of Diabetes and Metabolic Disorders
Bagher Larijani, Arash Hossein-Nezhad, Elham Feizabad, Zhila Maghbooli, Hossein Adibi, Majid Ramezani, Eghbal Taheri
BACKGROUND: This cross-sectional population-based study was conducted to elucidate the prevalence of vitamin D deficiency, bone turnover marker's variation and its influencing factors among adolescents of Tehran. METHODS: Totally 444 middle and high school (53.6 % in high school) students (both girls and boys) were recruited. A short food frequency questionnaire designed to estimate dietary calcium and vitamin D consumption. Serum levels of calcium, phosphorus, parathyroid hormone (PTH), bone specific alkaline phosphates, 25 (OH) vitamin D, osteocalcin, cross-linked C-telopeptide (CTX), total protein, albumin and creatinine were determined...
2016: Journal of Diabetes and Metabolic Disorders
Sardar Sindhu, Merin Koshy, Areej Abu Al-Roub, Nadeem Akhter, Saad Al Zanki, Shamsha Ali, Sriraman Devarajan, Rasheed Ahmad
[This corrects the article DOI: 10.1186/s40200-016-0264-4.].
2016: Journal of Diabetes and Metabolic Disorders
Mohsen Mehrabzadeh, Parvin Pasalar, Mostafa Karimi, Maryam Abdollahi, Maryam Daneshpour, Effat Asadolahpour, Farideh Razi
BACKGROUND: Diabetic nephropathy (DN) is one of the leading causes of death in patients with type 2 diabetes mellitus (T2DM). Several genome-wide association studies have introduced Engulfment and Cell Motility 1 (ELMO1) as a candidate gene which is associated with DN. This study assessed the association of ELMO1 gene polymorphisms with DN in order to investigate the effects of ELMO1 gene on susceptibility to DN in an Iranian population. METHODS: In the present study, 100 patients with T2DM, 100 patients with DN and 100 healthy subjects who were matched for sex were selected...
2015: Journal of Diabetes and Metabolic Disorders
Hossein Fakhrzadeh, Farshad Sharifi, Mahtab Alizadeh, Seyed Masoud Arzaghi, Yaser Tajallizade-Khoob, Ali Tootee, Sudabeh Alatab, Mojde Mirarefin, Zohre Badamchizade, Hadi Kazemi
BACKGROUND: Insulin resistance is of utmost importance as an underlying mechanism for increased risk of cardiovascular disease (CVD). We assessed the association between Homeostatic Model Assessment (HOMA-IR) and two surrogate subclinical atherosclerosis markers (SCA) among individuals with and without type 2 diabetes (DM), those who did not have any clinical presentation of the CVD. METHODS: In a cross-sectional study, 208 participants (105 diabetics and 103 non-diabetics) were enrolled from referred patients with diabetes to an academic outpatient clinic and their non-diabetic relatives in-law...
2015: Journal of Diabetes and Metabolic Disorders
Ramin Heshmat, Zahra Abdollahi, Farzaneh Sadeghi Ghotbabadi, Mahsa Rostami, Gita Shafiee, Mostafa Qorbani, Mohsen Rezaei Homami, Bagher Larijani, Forouzan Salehi
BACKGROUND: Healthy diet for maintaining a healthy weight and prevention of chronic disease is vital at all stages of life. The purpose of this study was to determine the nutritional knowledge, attitude, and practice among urban and rural households in Iran. METHODS: In this nation-wide study, 14,136 subjects were selected using a multistage cluster sampling method from 31 provinces of Iran. This study was on the households in rural and urban areas in Iran. Participants of this study were mothers or other members who were responsible for preparing meals for the whole family...
2015: Journal of Diabetes and Metabolic Disorders
Sardar Sindhu, Merin Koshy, Areej Abu Al-Roub, Nadeem Akhter, Saad Al Zanki, Shamsha Ali, Sriraman Devarajan, Rasheed Ahmad
BACKGROUND: Chronic inflammation is a hallmark of type-2 diabetes (T2D) and asthma. Monocyte chemoattractant protein (MCP)-1 or CCL-2 is a key regulator of monocytic infiltration into the sites of inflammation. The changes in systemic MCP-1 levels and its relationship with other inflammatory/immune markers in T2D patients with asthma remain unclear and have been addressed in this study. METHODS: Plasma samples from 10 asthmatic T2D patients (Group I: BMI = 37...
2015: Journal of Diabetes and Metabolic Disorders
Akbar Soltani, Farzane Saeidifard, Abbasali Keshtkar, Fatemeh Shakki Katouli
BACKGROUND: Incorrect estimation of pretest probability and misinterpretation of test results can change post-test probability in medical decision making. The aim of this study was to evaluate how physicians assess weight of findings of congestive heart failure (CHF) and how much their estimation is correlated with findings' Diagnostic Odd Ratio (DOR). METHODS: The participants were asked to answer a questionnaire based on a scenario of a patient having dyspnea...
2015: Journal of Diabetes and Metabolic Disorders
Marie Laurette Agbre-Yace, Elizabeth Eberechi Oyenusi, Abiola Olufunmilayo Oduwole, Michèle Dominique Ake, Jacko Rhedoor Abodo
BACKGROUND: World Health Organization has predicted a worldwide rise in the prevalence of diabetes mellitus. Cote d'Ivoire is not exempted as evidenced by such factors as obesity and sedentary life style amongst others. The objective of the study was to determine the prevalence of diabetes mellitus (DM) among children and adolescents in the district of Abidjan in Cote d'Ivoire. METHODS: A cross-sectional descriptive survey using a multi-stage sampling approach was conducted from March to April 2013...
2015: Journal of Diabetes and Metabolic Disorders
Fatemeh Sadat Haghighi, Masoud Rahmanian, Nasim Namiranian, Seyed Masoud Arzaghi, Farzane Dehghan, Fahime Chavoshzade, Fariba Sepehri
BACKGROUND: Migraine headache prevalence and triggers in type2 diabetes mellitus (T2DM) were investigated in previous studies but the results are contradictory. Therefore, in this study we examined the prevalence of migraine headache in diabetic patients in comparison with non-diabetic persons and its predisposing factors in 2014. METHODS: We enrolled 147 volunteer patients with T2DM and 150 healthy persons referred to the Yazd Diabetes Research Center and the Central Laboratory of Yazd, respectively, in 2014...
2015: Journal of Diabetes and Metabolic Disorders
Faeze Gohari, Hamid Reza Baradaran, Morteza Tabatabaee, Shabnam Anijidani, Fatemeh Mohammadpour Touserkani, Rasha Atlasi, Maryam Razmgir
OBJECTIVE: To determine the quality of randomized controlled clinical trial (RCT) reports in diabetes research in Iran. DESIGN: Systematized review. METHODS: We included RCTs conducted on diabetes mellitus in Iran. Animal studies, educational interventions, and non-randomized trials were excluded. We excluded duplicated publications reporting the same groups of participants and intervention. Two independent reviewers identify all eligible articles specifically designed data extraction form...
2015: Journal of Diabetes and Metabolic Disorders
Zhila Maghbooli, Solaleh Emamgholipour, Arash Hossein-Nezhad, Mahmood Shirzad, Sattar Gorgani Firuzjaee
BACKGROUND: We aimed to investigate the bone turnover markers in coronary artery disease (CAD) patients with and without type 2 diabetes (T2DM) in comparison with control subjects without CAD and T2DM. METHODS: This cross-sectional study was performed on 45 subjects undergoing elective heart surgery; either for coronary artery bypass grafting or for valve surgery. According to angiographic results, participants were grouped in two groups with CAD (n = 33) and without CAD (n = 12)...
2015: Journal of Diabetes and Metabolic Disorders
Alok Sharma, Geetanjali Paliwal, Nisha Upadhyay, Archana Tiwari
[This retracts the article DOI: 10.1186/s40200-015-0143-4.].
2015: Journal of Diabetes and Metabolic Disorders
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