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Journal of Diabetes and Metabolic Disorders

Bagher Larijani, Arash Hossein-Nezhad, Elham Feizabad, Zhila Maghbooli, Hossein Adibi, Majid Ramezani, Eghbal Taheri
BACKGROUND: This cross-sectional population-based study was conducted to elucidate the prevalence of vitamin D deficiency, bone turnover marker's variation and its influencing factors among adolescents of Tehran. METHODS: Totally 444 middle and high school (53.6 % in high school) students (both girls and boys) were recruited. A short food frequency questionnaire designed to estimate dietary calcium and vitamin D consumption. Serum levels of calcium, phosphorus, parathyroid hormone (PTH), bone specific alkaline phosphates, 25 (OH) vitamin D, osteocalcin, cross-linked C-telopeptide (CTX), total protein, albumin and creatinine were determined...
2016: Journal of Diabetes and Metabolic Disorders
Sardar Sindhu, Merin Koshy, Areej Abu Al-Roub, Nadeem Akhter, Saad Al Zanki, Shamsha Ali, Sriraman Devarajan, Rasheed Ahmad
[This corrects the article DOI: 10.1186/s40200-016-0264-4.].
2016: Journal of Diabetes and Metabolic Disorders
Mohsen Mehrabzadeh, Parvin Pasalar, Mostafa Karimi, Maryam Abdollahi, Maryam Daneshpour, Effat Asadolahpour, Farideh Razi
BACKGROUND: Diabetic nephropathy (DN) is one of the leading causes of death in patients with type 2 diabetes mellitus (T2DM). Several genome-wide association studies have introduced Engulfment and Cell Motility 1 (ELMO1) as a candidate gene which is associated with DN. This study assessed the association of ELMO1 gene polymorphisms with DN in order to investigate the effects of ELMO1 gene on susceptibility to DN in an Iranian population. METHODS: In the present study, 100 patients with T2DM, 100 patients with DN and 100 healthy subjects who were matched for sex were selected...
2015: Journal of Diabetes and Metabolic Disorders
Hossein Fakhrzadeh, Farshad Sharifi, Mahtab Alizadeh, Seyed Masoud Arzaghi, Yaser Tajallizade-Khoob, Ali Tootee, Sudabeh Alatab, Mojde Mirarefin, Zohre Badamchizade, Hadi Kazemi
BACKGROUND: Insulin resistance is of utmost importance as an underlying mechanism for increased risk of cardiovascular disease (CVD). We assessed the association between Homeostatic Model Assessment (HOMA-IR) and two surrogate subclinical atherosclerosis markers (SCA) among individuals with and without type 2 diabetes (DM), those who did not have any clinical presentation of the CVD. METHODS: In a cross-sectional study, 208 participants (105 diabetics and 103 non-diabetics) were enrolled from referred patients with diabetes to an academic outpatient clinic and their non-diabetic relatives in-law...
2015: Journal of Diabetes and Metabolic Disorders
Ramin Heshmat, Zahra Abdollahi, Farzaneh Sadeghi Ghotbabadi, Mahsa Rostami, Gita Shafiee, Mostafa Qorbani, Mohsen Rezaei Homami, Bagher Larijani, Forouzan Salehi
BACKGROUND: Healthy diet for maintaining a healthy weight and prevention of chronic disease is vital at all stages of life. The purpose of this study was to determine the nutritional knowledge, attitude, and practice among urban and rural households in Iran. METHODS: In this nation-wide study, 14,136 subjects were selected using a multistage cluster sampling method from 31 provinces of Iran. This study was on the households in rural and urban areas in Iran. Participants of this study were mothers or other members who were responsible for preparing meals for the whole family...
2015: Journal of Diabetes and Metabolic Disorders
Sardar Sindhu, Merin Koshy, Areej Abu Al-Roub, Nadeem Akhter, Saad Al Zanki, Shamsha Ali, Sriraman Devarajan, Rasheed Ahmad
BACKGROUND: Chronic inflammation is a hallmark of type-2 diabetes (T2D) and asthma. Monocyte chemoattractant protein (MCP)-1 or CCL-2 is a key regulator of monocytic infiltration into the sites of inflammation. The changes in systemic MCP-1 levels and its relationship with other inflammatory/immune markers in T2D patients with asthma remain unclear and have been addressed in this study. METHODS: Plasma samples from 10 asthmatic T2D patients (Group I: BMI = 37...
2015: Journal of Diabetes and Metabolic Disorders
Akbar Soltani, Farzane Saeidifard, Abbasali Keshtkar, Fatemeh Shakki Katouli
BACKGROUND: Incorrect estimation of pretest probability and misinterpretation of test results can change post-test probability in medical decision making. The aim of this study was to evaluate how physicians assess weight of findings of congestive heart failure (CHF) and how much their estimation is correlated with findings' Diagnostic Odd Ratio (DOR). METHODS: The participants were asked to answer a questionnaire based on a scenario of a patient having dyspnea...
2015: Journal of Diabetes and Metabolic Disorders
Marie Laurette Agbre-Yace, Elizabeth Eberechi Oyenusi, Abiola Olufunmilayo Oduwole, Michèle Dominique Ake, Jacko Rhedoor Abodo
BACKGROUND: World Health Organization has predicted a worldwide rise in the prevalence of diabetes mellitus. Cote d'Ivoire is not exempted as evidenced by such factors as obesity and sedentary life style amongst others. The objective of the study was to determine the prevalence of diabetes mellitus (DM) among children and adolescents in the district of Abidjan in Cote d'Ivoire. METHODS: A cross-sectional descriptive survey using a multi-stage sampling approach was conducted from March to April 2013...
2015: Journal of Diabetes and Metabolic Disorders
Fatemeh Sadat Haghighi, Masoud Rahmanian, Nasim Namiranian, Seyed Masoud Arzaghi, Farzane Dehghan, Fahime Chavoshzade, Fariba Sepehri
BACKGROUND: Migraine headache prevalence and triggers in type2 diabetes mellitus (T2DM) were investigated in previous studies but the results are contradictory. Therefore, in this study we examined the prevalence of migraine headache in diabetic patients in comparison with non-diabetic persons and its predisposing factors in 2014. METHODS: We enrolled 147 volunteer patients with T2DM and 150 healthy persons referred to the Yazd Diabetes Research Center and the Central Laboratory of Yazd, respectively, in 2014...
2015: Journal of Diabetes and Metabolic Disorders
Faeze Gohari, Hamid Reza Baradaran, Morteza Tabatabaee, Shabnam Anijidani, Fatemeh Mohammadpour Touserkani, Rasha Atlasi, Maryam Razmgir
OBJECTIVE: To determine the quality of randomized controlled clinical trial (RCT) reports in diabetes research in Iran. DESIGN: Systematized review. METHODS: We included RCTs conducted on diabetes mellitus in Iran. Animal studies, educational interventions, and non-randomized trials were excluded. We excluded duplicated publications reporting the same groups of participants and intervention. Two independent reviewers identify all eligible articles specifically designed data extraction form...
2015: Journal of Diabetes and Metabolic Disorders
Zhila Maghbooli, Solaleh Emamgholipour, Arash Hossein-Nezhad, Mahmood Shirzad, Sattar Gorgani Firuzjaee
BACKGROUND: We aimed to investigate the bone turnover markers in coronary artery disease (CAD) patients with and without type 2 diabetes (T2DM) in comparison with control subjects without CAD and T2DM. METHODS: This cross-sectional study was performed on 45 subjects undergoing elective heart surgery; either for coronary artery bypass grafting or for valve surgery. According to angiographic results, participants were grouped in two groups with CAD (n = 33) and without CAD (n = 12)...
2015: Journal of Diabetes and Metabolic Disorders
Alok Sharma, Geetanjali Paliwal, Nisha Upadhyay, Archana Tiwari
[This retracts the article DOI: 10.1186/s40200-015-0143-4.].
2015: Journal of Diabetes and Metabolic Disorders
Mojgan Sanjari, Akbar Soltani, Abdolrahim Habibi Khorasani, Maryam Zareinejad
BACKGROUND: To investigate the effect of supplementation of standard treatment (inhaled long-acting β2 agonists, anticholinergics and corticosteroids) with vitamin D on C reactive protein and pulmonary function tests in patients with COPD exacerbation. METHODS: HASH(0x3c0f0a0) DESIGN: Randomized, single-center, double-blind, placebo-controlled parallel trial. One teaching hospital Participants: 135 patients in pulmonary ward with moderate to severe COPD and exacerbations...
2015: Journal of Diabetes and Metabolic Disorders
Mohammad Reza Mohajeri Tehrani, Ali Ghorbani Abdehgah, Behnam Molavi, Salma Sefidbakht, Ali Reza Maleki, Amir Reza Radmard
BACKGROUND: Tumor induced hypoglycemia (TIH) is a rare clinical entity that can be caused by different mechanisms such as secretion of various substances, autoimmune disorders, massive tumoral infiltration of liver, and pituitary or adrenal glands destruction by tumors. Furthermore, any type of neoplasms can cause TIH. CASE PRESENTATION: The patient presented with a case of classic biphasic pulmonary blastoma (CBPB) with hypoglycemia. Chest CT scan showed 2 huge masses in the right hemi-thorax and multiple smaller masses located in the left hemi-thorax...
2015: Journal of Diabetes and Metabolic Disorders
Sai Yi Pan, Margaret de Groh, Alfred Aziz, Howard Morrison
BACKGROUND: Insulin resistance is a pathogenic factor for type II diabetes and has been associated with metabolic abnormalities and adverse clinical outcomes. The purpose of this study was to examine the relationship between insulin resistance and socio-demographics, adiposity and behavioral factors in the general, non-diabetic adult Canadian population. METHODS: Data for 3515 non-diabetic adults aged 18 to 79 years from the Canadian Health Measures Survey (cycles 1 and 2, 2007-2011) were analyzed...
2015: Journal of Diabetes and Metabolic Disorders
Mohammed M M Al-Haj Mohd, Hai Phung, Jing Sun, Donald E Morisky
BACKGROUND: Diabetes is a chronic medical condition and adherence to medication in adults with diabetes is important. Identifying predictors to medication adherence in adults with diabetes would help identify vulnerable patients who are likely to benefit by improving their adherence levels. METHODS: We conducted a cross-sectional study at the Dubai Police Health Centre between February 2015 and November 2015. Questionnaires were used to collect socio-demographic, clinical and disease related variables and the primary measure of outcome was adherence levels as measured by the Morisky Medication Adherence Scale (MMAS-8©)...
2015: Journal of Diabetes and Metabolic Disorders
Eman Sheshah, Amal Madanat, Fahad Al-Greesheh, Dalal Al-Qaisi, Mohammad Al-Harbi, Reem Aman, Abdul Aziz Al-Ghamdi, Khaled Al-Madani
BACKGROUND: Sudomotor dysfunction is manifested clinically as abnormal sweating leading to dryness of feet skin and increased risk of foot ulceration. The aim of this study was to test the performance of foot electrochemical skin conductance (ESC) to detect diabetic peripheral neuropathy and the risk of foot ulceration against traditional methods in Saudi patients with diabetes mellitus. METHODS: This cross-sectional study was conducted on 296 Saudi patients with diabetes mellitus...
2015: Journal of Diabetes and Metabolic Disorders
Thomas Wilke, Sabrina Mueller, Antje Groth, Bjoern Berg, Niklas Hammar, Katherine Tsai, Andreas Fuchs, Stephanie Stephens, Ulf Maywald
BACKGROUND: We compared all-cause mortality, major macrovascular events (MACE) and diabetes-related hospitalizations in T2DM-incident patients newly treated with metformin (MET) versus sulphonylureas (SU) monotherapy and in T2DM-prevalent patients newly treated with MET+SU versus MET+DPP4-inhibitor combination therapy. METHODS: We analysed anonymized data obtained from a German health fund. Patients were included when they had started MET versus SU therapy or MET+SU versus MET+DPP4 therapy between 01/07/2010 and 31/12/2011...
2015: Journal of Diabetes and Metabolic Disorders
Zhila Najafpour, Mohamadreza Jafary, Morteza Saeedi, Alireza Jeddian, Hossein Adibi
BACKGROUND: One of the most important concerns of health care systems in the world is the patient safety issues. Root Cause Analysis is a systematic process for identifying root causes and contributory factors of problems or events. The objective of this study is to review RCA reports to determine the effect size of contributory factors on adverse events through an organizational perspective. METHODS: This study was conducted in a tertiary care teaching hospital in 2014...
2015: Journal of Diabetes and Metabolic Disorders
George Patrick Akabwai, Davis Kibirige, Levi Mugenyi, Mark Kaddu, Christopher Opio, Rejani Lalitha, Edrisa Mutebi, Martha Sajatovic
BACKGROUND: Vitamin B12 deficiency is highly prevalent among adult individuals with diabetes yet screening is infrequent in Uganda. There are currently no published data regarding the prevalence of vitamin B12 deficiency and its associated factors among adult individuals with diabetes in sub-Saharan Africa. This study aimed at describing the prevalence and factors associated with vitamin B12 deficiency among this patient population in a resource constrained setting in sub-Saharan Africa...
2015: Journal of Diabetes and Metabolic Disorders
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