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Journal of the Pediatric Infectious Diseases Society

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https://www.readbyqxmd.com/read/30010914/continuous-monitoring-and-feedback-optimizes-blood-volume-inoculated-into-culture-bottles-in-the-pediatric-intensive-care-unit
#1
Kensuke Shoji, Norihiko Tsuboi, Ritsuro Arakawa, Kentaro Ide, Masashi Mikami, Akira Kato, Isao Miyairi
In this quasi-experimental study that included 3489 blood culture bottles, interventions that included the distribution of simple weight-stratified guidelines for recommended blood volume and monthly feedback to physicians were effective in optimizing blood volume for culture in a pediatric intensive care unit.
July 16, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/30016451/kingella-kingae-septic-arthritis-in-an-older-than-expected-child
#2
Sean Shahrestani, Amanda Evans, Erin McElvania Tekippe, Lawson A B Copley
Kingella kingae typically causes musculoskeletal infection in young children between the ages of 6 months and 4 years who may be in close contact with other similarly aged children who are colonized with the organism in their oropharynx. Kingella infections have rarely been described in older individuals with chronic medical conditions or immune compromise. This is a case report of a healthy, older child who developed an invasive infection due to Kingella kingae. Clinical and laboratory details are provided of an otherwise healthy 11-year-old female who developed an acute onset of septic arthritis of her shoulder...
July 14, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/30011009/increasing-clindamycin-and-trimethoprim-sulfamethoxazole-resistance-in-pediatric-staphylococcus-aureus-infections
#3
Dina F Khamash, Annie Voskertchian, Pranita D Tamma, Ibukunoluwa C Akinboyo, Karen C Carroll, Aaron M Milstone
The epidemiology of Staphylococcus aureus infection in children is dynamic. We conducted a retrospective observational study on pediatric clinical cultures, performed between 2005 and 2017, that grew S aureus to determine temporal trends in antibiotic resistance. Although methicillin resistance declined, clindamycin and trimethoprim-sulfamethoxazole resistance increased significantly, especially among community-onset isolates.
July 13, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/30010886/neonatal-bacteremia-and-cutaneous-lesions-caused-by-photorhabdus-luminescens-a-rare-gram-negative-bioluminescent-bacterium
#4
Ankhi Dutta, Anthony R Flores, Paula A Revell, Lisa Owens
Photorhabdus luminescens is a rare bacterium that causes human disease. In this report, we describe the case of a neonate with Photorhabdus luminescens bacteremia, including clinical presentation and treatment; we also report a literature review of rare human diseases.
July 13, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/30007329/treatment-of-neonatal-chlamydial-conjunctivitis-a-systematic-review-and-meta-analysis
#5
Andrew Zikic, Holger Sch√ľnemann, Teodora Wi, Ornella Lincetto, Nathalie Broutet, Nancy Santesso
Background: With the continued high prevalence of chlamydia worldwide and high risk of transfer from mothers to their infant during delivery, a need for safe and effective therapies for infants who acquire a chlamydial infection remains. We conducted a systematic review and meta-analysis of antibiotic treatments, including oral erythromycin, azithromycin, and trimethoprim, for neonatal chlamydial conjunctivitis. Methods: We searched Medline, Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) from their inception to July 14, 2017...
July 10, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29986059/evaluating-facility-infrastructure-for-prevention-of-mother-to-child-transmission-of-hiv-a-2015-assessment-of-major-delivery-hospitals-in-atlanta-georgia
#6
Somer L Smith, Ann M Chahroudi, Andres F Camacho-Gonzalez, Scott Gillespie, Bridget A Wynn, Martina L Badell, Andrea Swartzendruber, Rohan Hazra, Pascale Wortley, Rana Chakraborty
Objective: Our goal was to evaluate the infrastructure of programs for the prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) in major delivery units in the Atlanta, Georgia, metropolitan statistical area and to assess the knowledge, attitude, and practice of providers in these facilities around PMTCT. Methods: Hospital assessments and individual knowledge and practices were surveyed among 71 healthcare providers from March 2015 to March 2016 in 11 hospitals that deliver 40000 infants annually, which represents 70% of all deliveries in the Atlanta metropolitan statistical area...
July 6, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29982621/group-a-streptococcal-virulence-new-lessons
#7
Stanford T Shulman, James B Dale
No abstract text is available yet for this article.
July 6, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29982613/the-influenza-vaccine-mess
#8
Stanley A Plotkin
No abstract text is available yet for this article.
July 4, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29961833/update-from-the-advisory-committee-on-immunization-practices
#9
Sean T O'Leary, David W Kimberlin
The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts, meets 3 times per year to develop recommendations for vaccine use in the United States. There are 15 voting members, and their terms are for 4 years. ACIP members and Centers for Disease Control and Prevention staff discuss the epidemiology of vaccine-preventable diseases and vaccine research, effectiveness, safety data, and clinical trial results. Representatives from the American Academy of Pediatrics (including D...
June 28, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29939314/safety-and-tolerability-of-moxifloxacin-in-children
#10
Avika Dixit, Manjiree V Karandikar, Sarah Jones, Mari M Nakamura
Objectives: Moxifloxacin is not approved by the US Food and Drug Administration for pediatric use. Although its use might be indicated under certain conditions, data regarding its safety and tolerability in pediatric patients are limited. The primary objective of this study was to evaluate the safety of systemic moxifloxacin therapy in children. Methods: We conducted a retrospective observational study of patients aged <18 years who received oral or intravenous moxifloxacin at our institution between January 2011 and July 2016...
June 25, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29931284/performance-of-surveillance-case-definitions-in-detecting-respiratory-syncytial-virus-infection-among-young-children-hospitalized-with-severe-respiratory-illness-south-africa-2009-2014
#11
Brian Rha, Rebecca M Dahl, Jocelyn Moyes, Alison M Binder, Stefano Tempia, Sibongile Walaza, Daoling Bi, Michelle J Groome, Ebrahim Variava, Fathima Naby, Kathleen Kahn, Florette Treurnicht, Adam L Cohen, Susan I Gerber, Shabir A Madhi, Cheryl Cohen
Background: Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection (ALRTI) in young children, but data on surveillance case definition performance in estimating burdens have been limited. Methods: We enrolled children aged <5 years hospitalized for ALRTI (or neonatal sepsis in young infants) through active prospective surveillance at 5 sentinel hospitals in South Africa and collected nasopharyngeal aspirates from them for RSV molecular diagnostic testing between 2009 and 2014...
June 21, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29912364/intervention-and-acceptance-rates-support-handshake-stewardship-strategy
#12
Amanda L Hurst, Jason Child, Sarah K Parker
We instituted a new antimicrobial stewardship approach that involves review of all antimicrobial agents and communication of interventions in person by a pharmacist-physician team termed handshake stewardship. The acceptance rate in this study was 86%, intervention rates were higher with a physician, and interventions on antibiotics not reviewed by other strategies were made frequently.
June 15, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29912428/fever-and-back-pain-in-a-9-year-old
#13
Patrick Gavigan, Stacey Evans, Bindiya Bagga
No abstract text is available yet for this article.
June 14, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29905839/continuous-infusion-vancomycin-teaching-an-old-dog-new-tricks
#14
Kevin J Downes
No abstract text is available yet for this article.
June 14, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29897511/mycobacterium-abscessus-infections-in-children-a-review-of-current-literature
#15
Gabriella S Lamb, Jeffrey R Starke
There is limited literature on Mycobacterium abscessus infections in children and limited data about its diagnosis and management. The incidence of infections due to M abscessus appears to be increasing in certain populations and can be a significant cause of morbidity and mortality.Management of these infections is challenging and relies on combination antimicrobial therapy and debridement of diseased tissue, depending on the site and extent of disease. Treatment regimens often are difficult to tolerate, and the antimicrobials used can cause significant adverse effects, particularly given the long duration of therapy needed...
June 12, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29893957/outcomes-of-human-adenovirus-infection-and-disease-in-a-retrospective-cohort-of-pediatric-hematopoietic-cell-transplant-recipients
#16
Brian T Fisher, Craig L K Boge, Hans Petersen, Alix E Seif, Matthew Bryan, Richard L Hodinka, Ana Maria Cardenas, Dale R Purdy, Brandon Loudon, Adriana E Kajon
Background: Human adenoviruses (HAdVs) are associated with significant morbidity and death after hematopoietic cell transplantation (HCT). In this study, we sought to determine the incidence of HAdV infection among pediatric HCT recipients in the polymerase chain reaction (PCR) testing era, identify risk factors for viremia among patients undergoing HAdV surveillance, and assess the effectiveness of preemptive cidofovir. Methods: A single-center retrospective cohort of patients who underwent a transplant within a 10-year period was assembled...
June 8, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29889243/corrigendum
#17
(no author information available yet)
No abstract text is available yet for this article.
June 7, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29878238/cutaneous-leishmaniasis-in-an-american-adolescent-returning-from-israel
#18
Kimia G Ganjaei, Kira Lawton, Sunanda Gaur
We present here the case of a healthy 16-year-old American girl who returned from an organized trip to Israel with cutaneous leishmaniasis caused by Leishmania major; the infection was treated successfully with paromomycin-gentamicin ointment. She was initially misdiagnosed with staphylococcal and pseudomonal cellulitis. Although cutaneous leishmaniasis is seen only rarely in the United States, it should be considered when diagnosing new skin lesions after travel to affected countries.
June 6, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29860410/viral-loads-in-congenital-cytomegalovirus-infection-from-a-highly-immune-population
#19
Aiqiang Xu, Shiwen Wang, Wenqiang Zhang, Xiaofang Wang, Tongzhan Wang, Xiaolin Liu, Haiyan Wang, Wei Ma, Minal Amin, Sheila Dollard, Chengbin Wang
Among newborns with congenital cytomegalovirus (CMV) infection from China, there was no difference in CMV viral load in saliva specimens dried and stored at room temperature compared with those kept wet and stored cold, even after longer storage time for the former than the later (74 vs 58 days, P = .02).
June 1, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29850828/factors-associated-with-pneumonia-severity-in-children-a-systematic-review
#20
Preston Dean, Todd A Florin
Community-acquired pneumonia in children is associated with significant morbidity and mortality; however, data are limited in predicting which children will have negative outcomes, including clinical deterioration, severe disease, or development of complications. The Pediatric Infectious Diseases Society/Infectious Diseases Society of America (PIDS/IDSA) pediatric pneumonia guideline includes criteria that were modified from adult criteria and define pneumonia severity to assist with resource allocation and site-of-care decision-making...
May 30, 2018: Journal of the Pediatric Infectious Diseases Society
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