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International Journal of Applied and Basic Medical Research

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https://www.readbyqxmd.com/read/28251114/a-rare-case-of-primary-urachal-actinomycosis-mimicking-malignancy
#1
T Ayeesha Sithika, Hemalatha Ganapathy, A R Subashree
Primary actinomycosis occurring in urachal remnants is rarely documented in literature and may mislead the clinicians to diagnose urachal carcinoma. A 50-year-old man came with complaints of lower abdominal pain, dysuria, and dribbling of urine for 2 months. A vague mass of 7 cm was palpable in the suprapubic region. Imaging of the abdomen revealed an irregular mass seen superior to fundus of the urinary bladder appearing adherent to mesentery and bowel loops, suggesting an urachal remnant associated lesion with infiltration...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251113/rh-isoimmunized-pregnancy-managed-noninvasively-a-report-of-two-cases
#2
Deepti Jain
Pregnancy with Rh isoimmunization is a grave situation. Two women with indirect Coombs test (ICT) positive were managed conservatively with a favorable outcome. Peak systolic velocity (PSV) of middle cerebral artery (MCA) was measured every 2 weeks, and pregnancy continued till the value remained <1.5 mean of median. In one woman, the pregnancy could be prolonged to 37 weeks when delivery was induced and the neonate did not develop hyperbilirubinemia. In the second woman with bad obstetric history, when a highly positive ICT was reported, intravenous immunoglobulin (IVIG) was given in a single dose of 5 g every 2 weeks starting at 27 weeks, for a total of three doses, along with measurement of PSV of MCA...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251112/in-vitro-anticancer-activity-of-ethanolic-extracts-of-piper-nigrum-against-colorectal-carcinoma-cell-lines
#3
Akila Prashant, Chandini Rangaswamy, Anshu Kumar Yadav, Varun Reddy, M N Sowmya, Subbarao Madhunapantula
BACKGROUND: Piper nigrum (PN) is well known for its cytotoxic and pharmacological benefits. However, there is minimal documented evidence about its cytotoxic efficacy against colorectal carcinoma. We therefore sought to procure a precisely quantitative and qualitative result, pertaining the efficacy of an ethanolic extract of PN (EEPN) against colorectal carcinoma. MATERIALS AND METHODS: EEPN was prepared by subjecting dried PN seeds to gradient ethanol fractionation...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251111/treatment-of-dentinal-hypersensitivity-using-low-level-laser-therapy-and-5-potassium-nitrate-a-randomized-controlled-three-arm-parallel-clinical-study
#4
Ruchi Pandey, Pradeep Koppolu, Butchibabu Kalakonda, Bolla Vijaya Lakshmi, Ashank Mishra, Pathakota Krishnajaneya Reddy, Appaiah Chowdary Bollepalli
AIM: The present randomized study was aimed to compare the efficacy 5% potassium nitrate (KNO3) toothpaste, low-level laser therapy (LLLT), and LLLT with 5% KNO3 toothpaste in the treatment of dentinal hypersensitivity (DH). MATERIALS AND METHODS: Total of 45 patients complaining of DH with visual analog scale (VAS) score being ≥2 were recruited and were divided into three groups. Group A was treated with 5% KNO3 toothpaste, Group B using LLLT along with the application of 5% KNO3 toothpaste, and Group C using LLLT alone...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251110/correlation-of-friedewald-s-calculated-low-density-lipoprotein-cholesterol-levels-with-direct-low-density-lipoprotein-cholesterol-levels-in-a-tertiary-care-hospital
#5
Sunil Kumar Nanda, M Bharathy, Asha Dinakaran, Lopamudra Ray, K Ravichandran
BACKGROUND: One of the risk factors for the development of coronary heart disease is high low-density lipoprotein (LDL) cholesterol levels. National Cholesterol Education Program ATP III guidelines suggest drug therapy to be considered at LDL-cholesterol levels >130 mg/dl. This makes accurate reporting of LDL cholesterol crucial in the management of Coronary heart disease. Estimation of LDL cholesterol by direct LDL method is accurate, but it is expensive. Hence, We compared Friedewald's calculated LDL values with direct LDL values...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251109/effect-of-hydroalcoholic-extract-of-echinacea-purpurea-in-combination-with-meglumine-antimoniate-on-treatment-of-leishmania-major-induced-cutaneous-leishmaniasis-in-balb-c-mice
#6
Bahador Sarkari, Mobin Mohseni, Mahmoud Reza Moein, Reza Shahriarirad, Qasem Asgari
CONTEXT: Progressive resistance of Leishmania parasite to available drugs including, meglumine antimoniate, has been reported from various regions of the world, especially Iran. AIMS: This study was conducted to evaluate the effect of hydroalcoholic extract of Echinacea purpurea in a combination therapy with glucantime in the treatment of cutaneous leishmaniasis caused by Leishmania major. MATERIALS AND METHODS: Hydroalcoholic extract of E...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251108/effect-of-zoledronic-acid-on-fracture-healing-in-osteoporotic-patients-with-intertrochanteric-fractures
#7
Prabhnoor Singh Hayer, Anit Kumar Samuel Deane, Atul Agrawal, Rajesh Maheshwari, Anil Juyal
AIMS: To assess the effect of zoledronic acid (ZOL) on fracture healing in osteoporotic patients with intertrochanteric fracture based on radiological evaluation and to study the correlations between severity of osteoporosis, age, gender, and time taken to fracture union. SETTINGS AND DESIGN: An open label study was conducted on 43 patients at a tertiary care center. SUBJECTS AND METHODS: The osteoporosis status of all the included patients was documented using a double-energy X-ray absorptiometry scan...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251107/effect-of-different-phases-of-menstrual-cycle-on-brainstem-auditory-evoked-response
#8
Meenal Batta, Shashi Kant Dhir, Avnish Kumar, K D Singh
INTRODUCTION: The change in the hormonal levels during the three phases of menstrual cycle, namely, menstrual phase (hormonal withdrawal), proliferative phase (estrogen peak), and secretory phase (progesterone peak), influences the conduction velocities in the central auditory pathways. Variable findings of brainstem auditory evoked response (BAER) have been reported during different phases of menstrual cycle by different researchers. AIM: To study the effect of different phases of menstrual cycle on BAER...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251106/the-recurrence-frequency-of-breast-cancer-and-its-prognostic-factors-in-iranian-patients
#9
Ali Shahriari-Ahmadi, Mohsen Arabi, Mehrdad Payandeh, Masoud Sadeghi
BACKGROUND: Recurrent breast cancer (BC) after initial treatments is usually associated with poor outcome. The objective of this study is to evaluate baseline characteristics of BC patients to determine their prognostic influence of recurrences. MATERIALS AND METHODS: In this retrospective study of 481 BC patients, 182 patients who had recurrence within the first, second, or third 5 years after diagnosis were included in the study. The significant prognostic factors associated with late or very late recurrence were selected according to the Akaike Information Criterion...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251105/carbapenemase-producing-enterobacteriaceae-risk-factors-for-infection-and-impact-of-resistance-on-outcomes
#10
Shanthi Mariappan, Uma Sekar, Arunagiri Kamalanathan
BACKGROUND: Carbapenemase-producing Enterobacteriaceae (CPE) have increased in recent years leading to limitations of treatment options. The present study was undertaken to detect CPE, risk factors for acquiring them and their impact on clinical outcomes. METHODS: This retrospective observational study included 111 clinically significant Enterobacteriaceae resistant to cephalosporins subclass III and exhibiting a positive modified Hodge test. Screening for carbapenemase production was done by phenotypic methods, and polymerase chain reaction was performed to detect genes encoding them...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251104/effect-of-dipeptidyl-peptidase-4-inhibitors-on-acute-and-subacute-models-of-inflammation-in-male-wistar-rats-an-experimental-study
#11
Urmila Anil Kagal, Netravathi Basavaraj Angadi, Somnath Mallikarjun Matule
INTRODUCTION: The prevalence of Type 2 diabetes mellitus (T2DM) has reached alarming proportions due to the rapidly increasing rates of this disease worldwide. Preclinical and clinical studies have revealed elevated levels of inflammatory markers in a vast number of illnesses such as T2DM, obesity, and atherothrombosis collectively called metabolic syndrome leading to adverse cardiovascular events. Dipeptidyl peptidase 4 (DPP-4) inhibitors which are the enhancers of glucagon-like peptide 1 (GLP -1), could have anti-inflammatory potential which could help in reducing cardiovascular complications of diabetes and benefit patients suffering from the metabolic syndrome...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251103/correlation-of-enhanced-oxidative-stress-with-altered-thyroid-profile-probable-role-in-spontaneous-abortion
#12
Kaur Ramandeep, Gupta Kapil, Kaur Harkiran
BACKGROUND: Spontaneous abortion or miscarriage is defined as the loss of a clinically recognized pregnancy that occurs before 20 weeks of gestational age. Changes in thyroid function can impact greatly on reproductive function before, during, and after conception. Oxidative stress affects both implantation and early embryo development by modifying the key of transcription. Malondialdehyde (MDA) is a major breakdown product of split off from lipid peroxidation. Superoxide dismutase (SOD) is responsible for detoxification of superoxide anion and required for normal health and reproduction...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251102/incidence-of-distal-caries-in-mandibular-second-molars-due-to-impacted-third-molars-nonintervention-strategy-of-asymptomatic-third-molars-causes-harm-a-retrospective-study
#13
Nikhil Srivastava, Akshay Shetty, Rahul Dev Goswami, Vijay Apparaju, Vivek Bagga, Saurabh Kale
BACKGROUND: Removal of impacted third molars is the most common oral surgical procedure. Many investigators have questioned the necessity of removal in patients who are free of symptoms or associated pathologies. AIM: The aim of this retrospective study was to evaluate the incidence of caries on distal aspect of mandibular second molars in patients referred for corresponding third molar assessment and to identify its association with angular position and depth of the impacted mandibular third molars based on the classification of Pell and Gregory...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251101/comparative-analysis-of-colorectal-carcinoma-staging-using-operative-histopathology-and-computed-tomography-findings
#14
Subhash Chander Singla, Dhawal Kaushal, Harinder Singh Sagoo, Nalini Calton
BACKGROUND: The staging of colorectal carcinoma using 3 modalities viz operative, histopathology and CT scan has been subject of interest in accurately defining the extent of disease. This retrospective as well as prospective study was carried out at CMC, Ludhiana, Punjab from November 2011 to May 2014. AIM: The objective of this study was to assess the usefulness and accuracy of CT scan findings to state the extent and spread of colorectal malignancy and to correlate these findings with histopathological diagnosis...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251100/quantitative-nucleic-acid-amplification-methods-and-their-implications-in-clinical-virology
#15
REVIEW
Mini P Singh, Shipra Galhotra, Karnika Saigal, Archit Kumar, Radha Kanta Ratho
Recently, a number of techniques have been approved for quantification of viral nucleic acids in clinical samples. Viral load (VL) tests have considerable importance in the management of patients and are widely used in routine diagnosis. In clinical virology, VL testing are important to monitor the antiviral treatment, to initiate preemptive therapy, to understand pathogenesis, and to evaluate the infectivity. These tests have now become a part of many diagnostic and treatment guidelines. Considering the various challenges for in-house viral testing related to the standardization, validation, and precision; they are gradually being replaced by the United States Food and Drug Administration (US FDA) cleared tests...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28251099/xtandi-versus-indian-patent-laws-a-persepective
#16
EDITORIAL
Aditi Mridul Panditrao
No abstract text is available yet for this article.
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/27857904/successful-pregnancy-after-excision-of-cesarean-scar-endometriosis-with-uterovesicocutaneous-fistula-a-rare-case-report
#17
Sunil Kumar Juneja, Pooja Tandon, Isha Chopra
Scar endometriosis is an infrequent type of extrapelvic endometriosis. The most common extrapelvic form of endometriosis is cutaneous endometriosis, involving scar tissues occurring after obstetric or gynecologic procedures such as episiotomy, hysterotomy, cesarean section, and even laparoscopic surgery. The clinical presentation of scar endometriosis, i.e., tender swellings, mimics other dermatological and/or surgical conditions and delays the diagnosis. Scar endometriosis very rarely can get complicated with uterocutaneous fistula with a reported incidence of very few cases in world literature...
October 2016: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/27857903/orthokeratinized-odontogenic-cyst-masquerading-as-dentigerous-cyst
#18
Devi Charan Shetty, Ajit Singh Rathore, Anshi Jain, Natasha Thokchom, Neha Khurana
The orthokeratinized odontogenic cyst (OOC) is a rare developmental odontogenic cyst that has been considered as a variant of the keratocystic odontogenic tumor until Wright (1981) defined it as a different entity. Recognition of OOC as a unique entity has long been due, yet its inexplicable clinical, radiographic presentation resembling dentigerous cyst due to its association to an impacted tooth, and its histological features makes it rather perplexing. This is the report of a case of OOC in relation to an impacted maxillary canine and its immunohistochemical analysis with Ki-67...
October 2016: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/27857902/severe-congenital-cyclic-neutropenia-a-case-report
#19
Vidyavathi H Patil, Shivayogi M Hugar, Girish Balikai, Sudha Patil
Congenital cyclic neutropenia syndrome is a constitutional genetic disorder which is characterized by very low number of neutrophils (neutropenia). Patients suffering from this disorder clinically present with neutropenia at early age, history of recurrent fever, ulcerations in the oral cavity, gingivitis, and other recurrent infections. This paper describes a case report of a child with recurrent mouth ulcers, fever, and later diagnosed with severe congenital cyclic neutropenia. This also emphasizes the importance of identification of rare causes of immunosuppressive conditions in children presenting with recurrent oral ulcers and poor dental hygiene, to prevent long-term complications of oral cavity and also morbidity and mortality secondary to neutropenic sepsis...
October 2016: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/27857901/complete-agenesis-of-the-dorsal-pancreas-a-rare-clinical-entity
#20
Ambooken P Robert, Showkathali Iqbal, Mathew John
Complete agenesis of the dorsal pancreas (ADP) is an exceedingly rare congenital anomaly, compatible with life. The first case was reported in 1911 and so far around 100 cases have been reported in the world literature. Majority of the patients with this anomaly are asymptomatic or associated with abdominal pain, hyperglycemia, diabetes mellitus, and acute or chronic pancreatitis. We present a case report of a 34-year-old male with ADP, diagnosed incidentally during radiological evaluation for abdominal pain...
October 2016: International Journal of Applied and Basic Medical Research
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