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International Journal of Applied and Basic Medical Research

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https://www.readbyqxmd.com/read/29308372/a-case-of-oral-squamous-cell-carcinoma-in-a-nontobacco-habitu%C3%A3
#1
Karla Maria Carvalho, Poonam Ramnath Sawant, Anita Dhupar, Anita Spadigam
India is considered to be the oral cancer capital of the world. Oral squamous cell carcinoma is a multifactorial disease with tobacco and alcohol being considered major risk factors. However, there is a growing incidence of nonhabit (i.e., the absence of tobacco or alcohol) associated oral cancer. Difference is noted in demographics, site predilection, grade, and stage while comparing habit associated and nonhabit associated oral carcinoma. This warrants a need for a greater understanding of carcinogenesis without a known carcinogen...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308371/gingival-colored-porcelain-a-clinical-report-of-an-esthetic-prosthetic-paradigm
#2
Shital Jalandar Sonune, Shiv Kumar, Manish Shivaji Jadhav, Santosh Martande
Traditionally, periodontics has been instrumental in treating hard- and soft-tissue defect. Surgical and regenerative periodontal procedures can reconstruct the three-dimensional architecture of the hard- and soft-tissue defect. However, at times, these invasive procedures leave the patients with an esthetic problem. In such situations, the defects can be treated by the prosthetic approach. A predictable esthetically pleasing and functional outcome without any surgical procedure is being a choice of treatment for many...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308370/splenic-infarction-in-two-members-of-the-family-with-sickle-cell-trait-a-case-report-of-rare-complication
#3
Mithilesh Kumar Sinha, Babita Raghuwanshi, Nerbadyswari Deep Bag, Apurba Barman
Sickle cell trait is a highly prevalent condition. It is not a disease. However, it has been associated with few rare complications. Splenic infarction is one among them. The altitude-related hypoxia is the most common predisposing factor for this. The simultaneous occurrence of this complication in more than one member of a family is so rare that possibly, it is the only second such case report. We encountered this in two members of a family, the father and his son. They were on a religious visit to a 12,756 feet high mountain cave, when they developed pain left upper abdomen...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308369/intravascular-papillary-endothelial-hyperplasia-presenting-as-a-cystic-mass-in-the-scalp-with-underlying-bone-involvement-a-rare-entity
#4
Anshu Gupta, Sujata Chaturvedi, Karuna Jha, Wazid Nazir
Intravascular papillary endothelial hyperplasia (IPEH) also known as Masson's hemangioma is a rare benign reactive vascular lesion of the skin and subcutaneous tissue. It is usually confined to the lumen of preexisting vessels/vascular malformations. It is characterized histologically by papillary fronds lined by proliferating endothelial cells. This lesion is often misinterpreted as soft-tissue tumors and other benign and malignant lesions. We present a case of 13-year-old female with IPEH of scalp causing bony defect because of its rarity and diagnostic challenge, it posed due to nonspecific clinical and radiological findings...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308368/bilateral-three-headed-biceps-brachii-muscle-and-its-clinical-implications
#5
Sandeep Saluja, Sushant Swaroop Das, Dinesh Kumar, Preeti Goswami
Biceps brachii muscle frequently exhibits variant morphology in terms of origin, insertion, and mode of innervation. Nevertheless, the three-headed biceps brachii is described to be the most common variation. During routine cadaveric dissection, we came across a unique case of tricipital biceps brachii present on both the sides and variant course and branching pattern of musculocutaneous nerve. The third-headed biceps brachii emerged from the deep investing fascia of the brachialis muscle on both the sides...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308367/retinoic-acid-embryopathy
#6
Dipankar Mondal, Sreekanth R Shenoy, Santisena Mishra
Isotretinoin is a retinoid which is derived from Vitamin A. It is indicated for severe cystic acne treatment, but it has been classified as teratogenic. A wide spectrum of birth defects including craniofacial, heart, and nervous system malformations have been described with prenatal exposure to this drug. We report the case of a newborn with a history of prenatal exposure to isotretinoin with craniofacial defects, including left-sided anotia, right-sided microtia, complex congenital heart disease, and central nervous system malformation...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308366/a-rare-long-term-complication-of-physical-torture
#7
H K Ranil Sanjeewa, Muditha Vidanapathirana
The allegations made against custodians regarding ill treatments have been increased in Sri Lanka. However, their attention is grabbed by the immediate complications of torture, but not by late or delayed complications. A 35-year-old male was arrested for alleged housebreaking and kept under police custody. He alleged that he was hanged with his hands on several occasions. Six weeks after the incident, he presented to a tertiary care hospital with the weakness of his right shoulder. Examination revealed hyperpigmented scars over the left wrist and back of the left forearm with the right-sided medial winging of the scapula...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308365/neonatal-intramural-calcification-in-jejunal-atresia-case-report-of-a-rare-phenomenon
#8
S Suchitha, B N Kumarguru, Sunila, G V Manjunath
Intramural calcification in intestinal atresia is a rare type of intra-abdominal calcification. The exact etiology of intramural calcification remains obscure. A 1-day-old newborn male baby presented with signs of intestinal obstruction and was diagnosed to have jejunal atresia. The newborn underwent laparotomy with resection of atretic and dilated part of the small bowel. Histology of atretic part of jejunum and adjacent area revealed intramural calcification with extensive foreign-body giant cell reaction...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308364/tumor-infiltration-depth-as-a-prognostic-parameter-for-nodal-metastasis-in-oral-squamous-cell-carcinoma
#9
REVIEW
Padmaraj Hegde, Satadru Roy, Tripthi Shetty, B Rajendra Prasad, Urvashi Shetty
Oral squamous cell carcinoma (OSCC) has locoregional evolution, with frequent neck involvement. Significant number of studies have been undertaken to assess the parameters for treatment of N0 neck patients with a high likelihood of harboring occult node metastases. Many studies have indicated tumor infiltration depth (or tumor thickness) as one of the most important criteria in determining the further management. Growing evidence in the literature shows that tumor infiltration depth is a reliable parameter for predicting regional node involvement and patient survival in OSCC...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308363/association-of-glycemic-status-with-bone-turnover-markers-in-type-2-diabetes-mellitus
#10
Sweta Vilas Kulkarni, Suruthi Meenatchi, R Reeta, Ramasamy Ramesh, A R Srinivasan, C Lenin
Context: Type 2 diabetes mellitus has profound implications on the skeleton. Even though bone mineral density is increased in type 2 diabetes mellitus patients, they are more prone for fractures. The weakening of bone tissue in type 2 diabetes mellitus can be due to uncontrolled blood sugar levels leading to high levels of bone turnover markers in blood. Aims: The aim of this study is to find the association between glycemic status and bone turnover markers in type 2 diabetes mellitus...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308362/p53-codon-72-gene-polymorphism-studies-and-p53-expression-by-immunohistochemistry-in-oral-lesions-as-risk-factor-for-malignancy
#11
Nishi Tandon, Anand Narain Srivastava, Naseem Fatima, Syed Tasleem Raza, Vijay Kumar
Background: Wild-type p53 nuclear phosphoproteins are critical cell cycle regulatory tumor-suppressor gene. Genetic mutation of p53 gene is common in several head-neck cancers, usually associated with smoking and human papillomavirus (HPV) infection. In India, instead of HPV, tobacco/pan masala chewing is more commonly associated with oral cancer. Aim: The aim of this study was to investigate p53 codon 72 gene polymorphism and expression of p53 by immunohistochemistry (IHC) in oral lesions as a risk factor for its association with malignancy...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308361/piloting-direct-observation-of-procedural-skills-in-dental-education-in-india
#12
Gina Singh, Ravleen Kaur, Anushi Mahajan, Abi M Thomas, Tejinder Singh
Context: Direct observation of procedural skills (DOPS) and corrective feedback are one of the most important tools to promote skill learning. Authentic and pedagogically effective feedback can come out only when based on direct observation of the learners' performance. Use of DOPS, particularly in dental education in India is very uncommon. Aims: To pilot DOPS on undergraduate dental students in the specialty of periodontia. Materials and Methods: The faculty was oriented to the concept and use of this modality during a 1 h session, which included a video demonstration...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308360/influence-of-lactobacillus-acidophilus-and-lactobacillus-plantarum-on-wound-healing-in-male-wistar-rats-an-experimental-study
#13
Anupama M Gudadappanavar, Prashant R Hombal, Somling S Timashetti, S B Javali
Context and Aim: Probiotics have been documented with various pleotropic effects other than improving general gut health, but the potential benefits of strain-specific Lactobacillus on wound healing are unknown. Hence, the objective of the study is to evaluate and compare the wound healing property of Lactobacillus acidophilus and Lactobacillus plantarum on various wound models in male Wistar rats. Subjects and Methods: Excision wound, resutured incision wound, and dead space wounds were inflicted under light thiopentone anesthesia in male Wistar rats (n = 6, in each group)...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308359/evaluation-of-risk-factors-for-exchange-range-hyperbilirubinemia-and-neurotoxicity-in-neonates-from-hilly-terrain-of-india
#14
Deeksha A Singla, Seema Sharma, Milap Sharma, Sanjeev Chaudhary
Background and Aim: Neonatal hyperbilirubinemia continues to be the most common cause of hospital admissions and readmissions in the neonatal population worldwide and this pattern continues despite attempts to identify neonates at risk of pathological hyperbilirubinemia. Therefore, this study aimed to study the risk factors for severe hyperbilirubinemia in neonates. Materials and Methods: An observational prospective study was undertaken for 1 year in neonates with hyperbilirubinemia requiring double volume exchange transfusion in neonatology unit of a tertiary rural health care hospital...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308358/a-qualitative-and-quantitative-comparison-of-adverse-drug-reaction-data-in-different-drug-information-sources
#15
Gurpreet Kaur Randhawa, Rajeev Sharma, Navyug Raj Singh, Nidhi Sharma
Background: For safe use of medicines, awareness regarding the existing knowledge of adverse drug reactions (ADRs) is essential to prevent, identify, and manage them. Aim: The present study is planned to assess variation in documented ADRs of antihypertensive drugs in various sources of drug information. Material and Methods: A cross-sectional, observational study was undertaken to analyze the different sources of ADRs-related information...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308357/postoperative-analgesia-with-intravenous-paracetamol-and-dexmedetomidine-in-laparoscopic-cholecystectomy-surgeries-a-prospective-randomized-comparative-study
#16
Ridhima Sharma, Raghav Gupta, Ripon Choudhary, Sukhminder Jit Singh Bajwa
Background and Aim: Therapeutic use of nonopioid analgesic such as paracetamol (PCM) is an alternative to opioids, so to avoid the established side effects associated with opioids, PCM is commonly used due to its analgesic and antipyretic effects. Recently, dexmedetomidine has also emerged on the anesthesia front with a potential role of providing postoperative analgesia. The present study was conducted to compare and assess the quality and duration of analgesia with PCM and dexmedetomidine using visual analog scale (VAS)...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29308356/inclusion-of-medical-colleges-as-adverse-drug-reaction-monitoring-centers-under-pharmacovigilance-programme-of-india-missing-the-targets
#17
EDITORIAL
Rajiv Mahajan
No abstract text is available yet for this article.
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28904928/prenatal-sonographic-diagnosis-of-hypoplastic-left-heart-syndrome
#18
Raghu Teja Sadineni, B Santh Kumar, N B Chander, Durga Mahita Boppana
Hypoplastic left heart syndrome (HLHS) represents a variety of cardiac malformations that may result from errors in the early stages of cardiac development. HLHS includes a wide spectrum of cardiac malformations including hypoplasia of the left ventricle, ascending aorta, hypoplasia, or atresia of the aortic and mitral valves. Over the recent years, the improved resolution of advanced equipment with awareness and increased performance of second-trimester ultrasound examinations for the assessment of fetal anomalies have helped in understanding the spectrum and have expanded our knowledge of HLHS...
July 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28904927/cervical-lymph-nodes-harbinger-of-benign-inclusions-as-well-as-metastatic-deposits-of-thyroid-malignancy
#19
Samarth Shukla, Sourya Acharya
Lymph nodes can be harbinger to benign epithelial inclusions as well as metastatic deposits. Cervical lymph nodes are home to benign epithelial inclusions from thyroid better known as lateral aberrant thyroid as well as inclusions from salivary gland due to the unique embryologic origins of nodes with these organs. We present a case of a young female suspected of thyroid malignancy who was intraoperative diagnosed by frozen sections with papillary carcinoma of the thyroid along with bilateral cervical nodes (Level I-V) positive for reactive lymphadenopathy with Level II node being positive to benign salivary gland inclusions and Level VI node being positive to metastatic deposits of papillary carcinoma of the thyroid...
July 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28904926/toxic-brain-injury-with-nitrobenzene-poisoning
#20
Akshay Kumar, Chintan Bhavsar, Praveen Aggarwal, Nayer Jamshed
Acute methemoglobinemia secondary to nitrobenzene ingestion is a rare but well-known clinical entity. It is extremely important to identify such patients as rapid and effective management with methylene blue and other supportive measures will often save these lives. We present a rare and unfortunate case of a girl who developed acute toxic brain injury following nitrobenzene ingestion and succumbed.
July 2017: International Journal of Applied and Basic Medical Research
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